LOCUS       DAVBOH010000001        75363 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOH010000001 DAVBOH010000000
VERSION     DAVBOH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.001"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ873_000001"
     CDS             complement(141..1010)
                     /locus_tag="VQ873_000001"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3106351.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ873_000002"
     CDS             complement(1012..2298)
                     /locus_tag="VQ873_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3106352.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ873_000003"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ873_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3106353.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ873_000004"
     CDS             complement(3386..4420)
                     /locus_tag="VQ873_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3106354.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ873_000005"
     CDS             complement(4449..5882)
                     /locus_tag="VQ873_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3106355.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ873_000006"
     CDS             complement(5898..6884)
                     /locus_tag="VQ873_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3106356.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ873_000007"
     CDS             complement(6886..7989)
                     /locus_tag="VQ873_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3106357.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ873_000008"
     CDS             complement(7979..8824)
                     /locus_tag="VQ873_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3106358.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ873_000009"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ873_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3106359.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ873_000010"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ873_000010"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3106360.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ873_000011"
     CDS             complement(11219..11695)
                     /locus_tag="VQ873_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3106361.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ873_000012"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ873_000012"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3106362.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ873_000013"
     CDS             complement(13063..13401)
                     /locus_tag="VQ873_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3106363.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ873_000014"
     CDS             complement(13412..14515)
                     /locus_tag="VQ873_000014"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3106364.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ873_000015"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ873_000015"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3106365.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ873_000016"
     CDS             complement(15701..16768)
                     /locus_tag="VQ873_000016"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3106366.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ873_000017"
     CDS             complement(16787..17641)
                     /locus_tag="VQ873_000017"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3106367.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ873_000018"
     CDS             complement(17631..18308)
                     /locus_tag="VQ873_000018"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3106368.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ873_000019"
     CDS             complement(18305..19468)
                     /locus_tag="VQ873_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3106369.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ873_000020"
     CDS             complement(20155..21789)
                     /locus_tag="VQ873_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106370.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ873_000021"
     CDS             complement(21770..22519)
                     /locus_tag="VQ873_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106371.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ873_000022"
     CDS             22698..24152
                     /locus_tag="VQ873_000022"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3106372.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ873_000023"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ873_000023"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3106373.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ873_000024"
     CDS             complement(26881..27366)
                     /locus_tag="VQ873_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3106374.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ873_000025"
     CDS             complement(27641..27880)
                     /locus_tag="VQ873_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106375.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ873_000026"
     CDS             complement(28141..29211)
                     /locus_tag="VQ873_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3106376.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ873_000027"
     CDS             complement(29208..29981)
                     /locus_tag="VQ873_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3106377.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ873_000028"
     CDS             complement(29978..30784)
                     /locus_tag="VQ873_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3106378.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ873_000029"
     CDS             complement(30765..31922)
                     /locus_tag="VQ873_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106379.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ873_000030"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ873_000030"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3106380.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ873_000031"
     CDS             complement(33099..33851)
                     /locus_tag="VQ873_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3106381.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ873_000032"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ873_000032"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3106382.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ873_000033"
     CDS             34734..36005
                     /locus_tag="VQ873_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3106383.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36840)
                     /locus_tag="VQ873_000034"
     CDS             complement(36025..36840)
                     /locus_tag="VQ873_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3106384.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANVVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(36997..37650)
                     /gene="phoU"
                     /locus_tag="VQ873_000035"
     CDS             complement(36997..37650)
                     /gene="phoU"
                     /locus_tag="VQ873_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3106385.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37662..38420)
                     /gene="pstB"
                     /locus_tag="VQ873_000036"
     CDS             complement(37662..38420)
                     /gene="pstB"
                     /locus_tag="VQ873_000036"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3106386.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38433..39236)
                     /gene="pstB"
                     /locus_tag="VQ873_000037"
     CDS             complement(38433..39236)
                     /gene="pstB"
                     /locus_tag="VQ873_000037"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3106387.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39247..40131)
                     /gene="pstA"
                     /locus_tag="VQ873_000038"
     CDS             complement(39247..40131)
                     /gene="pstA"
                     /locus_tag="VQ873_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3106388.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40121..41038)
                     /gene="pstC"
                     /locus_tag="VQ873_000039"
     CDS             complement(40121..41038)
                     /gene="pstC"
                     /locus_tag="VQ873_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3106389.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41038..41916)
                     /gene="pstS"
                     /locus_tag="VQ873_000040"
     CDS             complement(41038..41916)
                     /gene="pstS"
                     /locus_tag="VQ873_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3106390.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42490..43794)
                     /locus_tag="VQ873_000041"
     CDS             complement(42490..43794)
                     /locus_tag="VQ873_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3106391.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43795..44568)
                     /locus_tag="VQ873_000042"
     CDS             complement(43795..44568)
                     /locus_tag="VQ873_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3106392.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44558..44836)
                     /locus_tag="VQ873_000043"
     CDS             complement(44558..44836)
                     /locus_tag="VQ873_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3106393.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44836..45237)
                     /locus_tag="VQ873_000044"
     CDS             complement(44836..45237)
                     /locus_tag="VQ873_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3106394.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45447..46064)
                     /locus_tag="VQ873_000045"
     CDS             complement(45447..46064)
                     /locus_tag="VQ873_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3106395.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46054..46827)
                     /locus_tag="VQ873_000046"
     CDS             complement(46054..46827)
                     /locus_tag="VQ873_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3106396.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46838..47575)
                     /locus_tag="VQ873_000047"
     CDS             complement(46838..47575)
                     /locus_tag="VQ873_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3106397.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47580..48710)
                     /locus_tag="VQ873_000048"
     CDS             complement(47580..48710)
                     /locus_tag="VQ873_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3106398.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     YGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48794..49183)
                     /locus_tag="VQ873_000049"
     CDS             complement(48794..49183)
                     /locus_tag="VQ873_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3106399.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49199..49582)
                     /locus_tag="VQ873_000050"
     CDS             complement(49199..49582)
                     /locus_tag="VQ873_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3106400.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49583..50371)
                     /locus_tag="VQ873_000051"
     CDS             complement(49583..50371)
                     /locus_tag="VQ873_000051"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3106401.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50364..51299)
                     /locus_tag="VQ873_000052"
     CDS             complement(50364..51299)
                     /locus_tag="VQ873_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3106402.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51429..51605)
                     /locus_tag="VQ873_000053"
     CDS             complement(51429..51605)
                     /locus_tag="VQ873_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3106403.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51745..52452)
                     /locus_tag="VQ873_000054"
     CDS             complement(51745..52452)
                     /locus_tag="VQ873_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3106404.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52603..53631
                     /gene="queA"
                     /locus_tag="VQ873_000055"
     CDS             52603..53631
                     /gene="queA"
                     /locus_tag="VQ873_000055"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3106405.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54292..54681)
                     /locus_tag="VQ873_000056"
     CDS             complement(54292..54681)
                     /locus_tag="VQ873_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3106406.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54735..55426)
                     /locus_tag="VQ873_000057"
                     /pseudo
     CDS             complement(54735..55426)
                     /locus_tag="VQ873_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56141..56692)
                     /locus_tag="VQ873_000058"
     CDS             complement(56141..56692)
                     /locus_tag="VQ873_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106407.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57042..57866)
                     /gene="nadE"
                     /locus_tag="VQ873_000059"
     CDS             complement(57042..57866)
                     /gene="nadE"
                     /locus_tag="VQ873_000059"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3106408.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57863..59323)
                     /locus_tag="VQ873_000060"
     CDS             complement(57863..59323)
                     /locus_tag="VQ873_000060"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3106409.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59439..59927)
                     /locus_tag="VQ873_000061"
     CDS             complement(59439..59927)
                     /locus_tag="VQ873_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106410.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59917..60126)
                     /locus_tag="VQ873_000062"
     CDS             complement(59917..60126)
                     /locus_tag="VQ873_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3106411.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60512..60992)
                     /locus_tag="VQ873_000063"
                     /pseudo
     CDS             complement(60512..60992)
                     /locus_tag="VQ873_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61152..61886)
                     /locus_tag="VQ873_000064"
     CDS             complement(61152..61886)
                     /locus_tag="VQ873_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106412.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62221..62691)
                     /locus_tag="VQ873_000065"
     CDS             complement(62221..62691)
                     /locus_tag="VQ873_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3106413.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HEAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(62712..62951)
                     /locus_tag="VQ873_000066"
     CDS             complement(62712..62951)
                     /locus_tag="VQ873_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3106414.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            complement(63200..63511)
                     /locus_tag="VQ873_000067"
     CDS             complement(63200..63511)
                     /locus_tag="VQ873_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106415.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63526..64812)
                     /locus_tag="VQ873_000068"
     CDS             complement(63526..64812)
                     /locus_tag="VQ873_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3106416.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65435..65617
                     /locus_tag="VQ873_000069"
     CDS             65435..65617
                     /locus_tag="VQ873_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3106417.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            65627..65977
                     /locus_tag="VQ873_000070"
     CDS             65627..65977
                     /locus_tag="VQ873_000070"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3106418.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            65985..67175
                     /locus_tag="VQ873_000071"
     CDS             65985..67175
                     /locus_tag="VQ873_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3106419.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67690..68682)
                     /locus_tag="VQ873_000072"
     CDS             complement(67690..68682)
                     /locus_tag="VQ873_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3106420.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68842..70596
                     /locus_tag="VQ873_000073"
     CDS             68842..70596
                     /locus_tag="VQ873_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106421.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70580..72301
                     /locus_tag="VQ873_000074"
     CDS             70580..72301
                     /locus_tag="VQ873_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106422.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72312..72896
                     /locus_tag="VQ873_000075"
     CDS             72312..72896
                     /locus_tag="VQ873_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3106423.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72896..73591
                     /locus_tag="VQ873_000076"
     CDS             72896..73591
                     /locus_tag="VQ873_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3106424.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            73579..74943
                     /locus_tag="VQ873_000077"
     CDS             73579..74943
                     /locus_tag="VQ873_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106425.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        23221 a        16031 c        13685 g        22426 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttggtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaaattaca taaaacaaat atccattttt ttgatttcat
    36841 aaataaacaa cctttctgtt aattttgtat aattataacg atatccaagt tacttgtcaa
    36901 gtgtttttta aatttttatc tcaaaaatat tttttcgttc aaaaaaagga gccatcagtt
    36961 gatttcaagc tcctttttat acagaattaa actattttat agttcgacaa tcttacctgt
    37021 ttcaaagtag acaacccatt cacagatatt tttagcataa tcaccgatac gctccaagta
    37081 ggaaataact tggaaataat cacgacccgt aacaatggct tctggatttt tcttaatctc
    37141 ttcagtcgca aggtcacgga tagtttcaaa atagtggtta atttgctcat ccatggaggc
    37201 cacccggtat gcgtcgtcaa cagaaccatt aagataaaga tcaagtgctg cttcaacaac
    37261 gcttttaact tcacgtccca tttttttaat ttcttcctct acagctggga tgcgttcttc
    37321 ccccttcata cggatggttg cctgggcaat ggctacagcg tgatccccca tacgctccac
    37381 atctgataca gccttaagga cagtcaagac tgtacgcaaa tcttgagaga ctggttgttg
    37441 gagtgcgatc atttcaaatg atttcttttc cagtttcact tcgtattcat ttacttctgc
    37501 atcatcttct atgacctctt ttgccaggtc acggtcatgc gtgacaaaag cacgtaccgt
    37561 acgattgatt tgtgagagca cttcttgtcc catagcgtag aactggttat gtaatttctc
    37621 taaatcttct tcaaattgag atcgtaacat ctttcatctc cttatccaaa ttttcctgta
    37681 atatagtctt ccgtttcctt gtgttgggga tcaaggaaca tctgcttggt atcattaaat
    37741 tcaatcaaat ctccatctag gaaaaatcct gtcttatcag agatacgtga agcttgctgc
    37801 atggaacggg ttaccagaag catggtgtac ttgtctttta gaccatacaa ggtttcctca
    37861 attttaccag ctgaaatcgg atccaaagcc gaagttggct catccaagag gatgatttta
    37921 ggactagttg ccaagacacg ggccacgcag acacgctgct gttgaccacc tgacaatcca
    37981 atagctgaat catatagacg atccttgacc tcatcccaga tagaggcacc ttgcaaggct
    38041 ttttctacgg cttcatccag aacctgctta tccttaattc cattgatacg aagcccgtag
    38101 acaacattct catagatagt catagggaaa ggattaggtt gttggaaaac cattccgatt
    38161 tccttacgta attcaaccgt atctgtacgc ggactgtaga tgttgtgacc attgtacacc
    38221 acggatccag ttgtggtcac ctctggattg agatctccca tgcggttgag agacttgagg
    38281 agggttgact tccctgatcc agatggacca atcaaggctg taatttcctt aggttggaaa
    38341 gatagggaaa cactattcaa agccttcttt ttattataat aaacggacag gtctgatacc
    38401 tgtaaaatcg catctgtcat acggtttcct ttctaaccaa agtgaccaga tacatagtca
    38461 ttggtggact gtagcttggc attttggaaa atagttgcag tcttatcata ctcaatcaaa
    38521 tcacccaagt aaaagaagcc tgtatagtca cttgcacgag cagcctgctg catattatgc
    38581 gttacaatga tgatggtaaa gtttttcttg agctcaaaca tggtctcttc tagttgcatg
    38641 gtcgcaatcg gatccaaggc tgaggctggc tcatccatta agaggatatc tggcttaaca
    38701 gagatggcac gagcgataca gagacgttgt tgctgaccac ctgataaggt caaggctgac
    38761 ttgtggagat cgtctttaac ctgatcccag agggcagcct gacgaaggga ggtttctacg
    38821 atttcatcta ggacttgctt atccttaact ccagcacgtt catgcgcaaa ggtgatatta
    38881 cggtaaattg acttagcaaa tggattgggg cgttgaaaaa ccattccaat gtgtttacgc
    38941 atttcataaa cgttgatttc tggacggttg acatcaattc cacgatagag aatctgccca
    39001 gttactttag caatatcaat agtatcattc atgcgattga gactgcgtaa gtaggtagat
    39061 ttccccgacc ccgacggacc aatcaaagct gtaattttat ttctttcaaa ttgcatatca
    39121 atccccttaa tggattcatt tttaccatag taaacatgga catccttagt agaaagggct
    39181 actttttctt caggaaaggt aaggatatgc ttctcatccc agttatatgt tgacatggct
    39241 tctcctttag gcagcggtta atttcttgtg tagatagctt ccgaacttac gagctccaaa
    39301 gttaaaaatc aggataaaga tcaggagcac agcggcagaa cctgctgata caatggttcc
    39361 atctggaata gtgccttcac tattgacttt ccagatatgg acagccaagg tttctgcttg
    39421 acggaagata gagatggggc tagtcacact gaggatattc cagttagacc agtcaagagc
    39481 tggcgccgat tgccctgctg tatagatcag agctgcagct tcgccaaaga tacgaccaga
    39541 tgccaagacg acacccgtta caatacctgg aagcgcttct ggaataacaa catgaaccac
    39601 tgtctcccag cgagaaatcc caagagccag accagcctca cgttgggtat ggtgaacgtg
    39661 tttcaaacta tcctctacat tacgcgtcat ctgaggcaaa ttaaagactg tcaaggccaa
    39721 ggcacctgaa atgattgaaa atccatactc aaactggact acaaagatca agtaaccaaa
    39781 gagacccacc accactgatg gtaaagagga caagatttca atacaagtcc gcacaaagtt
    39841 ggtaacagga ccttttttag catattcagc caagtaaatc ccagctccca tagaaagagg
    39901 tacagaaata atcaaggtaa tgaccaatag gaaaaaggaa ttgtaaagct gaatgccaat
    39961 cccaccacct gcttgaaaag cagaagacct tccagtcaag aaagaccaag agatatgggg
    40021 caagccccga accaagatat agagaatcaa ggaagccaag attgtcacaa tgatgctagc
    40081 aatcgtatag aggacagctg ttgcaagttt atctaatttc ttagcgcgca taatttttct
    40141 ttcctctttc tttcgtaatc aatttaatca cactgttaaa aactaaactc atcaagagca
    40201 gtaccaaggc cagtgaccag agaacattat tatttacagt tcccatgaca gtgttcccaa
    40261 ttcccatagt taatatagaa gttaaagttg cagctggtgt ggtcaaggaa gttgggataa
    40321 cagctgagtt tccgacaacc atctggatag ctaaagcctc accaaaggca cgcgccatcc
    40381 caaagaccac tgcagtgaaa ataccagaac gggccgcctt caagatcaca cgccagatag
    40441 tctgccagcg agtggctccc atagcgaaac ttgcctcacg ataataacga ggaaccgcac
    40501 gcaagctatc cgttgtcata aaggttacgg tcggcaaaat catgacaaag aggacggaaa
    40561 tccctgacaa aatcccaaaa ccagtcccac caaagacact gcgaacaaag ggaacgacga
    40621 cttgcaagcc aataaatccg tacactactg aaggaatccc aaccaggagt tcaatagctg
    40681 gttgcaaaat cttcgcccct tttggtgata cttcggtcat aaaaactgct gcaccaatag
    40741 caaagggtgt tgcgataagg gctgagagaa tggtaacgat aaaggaaccc aaaatcatag
    40801 gaagggcacc aaattcttta ctagaaggat tccaagttcc tcccaaaaga aagtcaaaga
    40861 tattcacacc attgacaaag aaggtcgaca agcctttttg cgctacgaaa accaaaatca
    40921 tggccacaag gatgactatc aaagaaagac aggcaaaggt caaacctttt cctaatttct
    40981 ccagacgaga attctttgat ggaagcaaca ttttcttagc taattcttct tgattcatta
    41041 ttgtctccct tccaacactg tcacagttcc ggcagcatct ttttcaacct tcatttcctt
    41101 aatcggaata tacttcaatc ctttgacaat cccttcttgg gtctcatccg agagaacaaa
    41161 attgagaaat tctgcagcta actcattggg ctgccccaat gtatacatat gctcataaga
    41221 ccacaagggc caattattgc tacttatatt ttctggactt aagtcatagc cattcaactt
    41281 catgcttttg accgaatcat ctatataggt aagagataaa taagagatag ctcctggact
    41341 ttttgatacg attgatttta ccgctccatt tgaatcctgc tcctgacttt gcatggcaga
    41401 ctgaccttcc ataatgacag tatcaaaggt agcacgagag ccagagccgg ctgcccgatt
    41461 gataacagag atgggtaagt ccttaccacc aacctctttc caattggtta cctcacctat
    41521 gaagatttga cgaagttgct ctgtcgttag attatcaaca tcaacctcct tattgacaat
    41581 cagagccaag ccagctaccg cgaccttgtg gtcaacaaga gcagaagcat caattccgtc
    41641 tttttcctca gcaaatacat ctgagtttcc tatatcaact gccccagact gaacctggga
    41701 caagcctgta ccagaacctc ccccttggac attgaccgtt tttccaacat ggatcgtgcc
    41761 aaattcatct gccgctactt caaccaaggg ttgcaaggca gttgagccaa cagccgttat
    41821 ggattctcca cgatcaatcc agctagcaca gcctactaaa caagccgtca gccaaaaagc
    41881 gataagagac agagcaagct tttttctttt tttcactgtt tttctcctcg aaaataatta
    41941 tgaatactgt gaatttttta agtagttctt tatgagttga cgcatgaatt cttaccaaat
    42001 ttctgcgcaa ttgattattt atataatata ggctatatta ctctttccta acctcctttt
    42061 ttcatatgtg gataaaatct cttgtctatc ccttccccca ttgtcaccca ttatagtcat
    42121 ttcgtgtctc tttttcccct ttttaatgca agggaaatta ctctccttag atgataatct
    42181 aaaagctaga aaggtatctc aaatctctct actctcccag actagtttac aactaaaagg
    42241 aaaagattct attttatgag aaatctagtt tacaagcggt aagaacgcta ataactaaac
    42301 ttcttgtact ctttgaaaat ctcttcaaag cagtgttttg agctatctat ggctagcttc
    42361 ctagtttgct ctttgatttt catcgagtag taaaactaca tgtgatggca atcaagatat
    42421 caagaatcat cctactaaaa aaatccatac tttcactata acatagaata agatatttga
    42481 ctagcatttt catttgaatc tgaggccttt tggaaaataa tttttcaaaa catttccagt
    42541 aacctttgca aagcccaagc cattgccttt aaccaaaact tggtaccaac catttggcag
    42601 actttctgcc agctgaacgg tttctccagc cgcatacttg acaaactctt cttggccaat
    42661 ttcaaccgac tgttcgacct gactcggttt caaggctaaa ccaagagcga aactgggctc
    42721 aaagcgtttc ttcttaaaag tacccagatg cagtccattg cgagcaatct tgagcttccc
    42781 taaatctggc aaaagttctg gcaagagata aagctggtct ccaaaaatct gcaagatacc
    42841 cggtagattg accttcaaat ggttttgggc aaattcctgc cacaaggcaa cttgttcacg
    42901 gctgaggtta ctcttacttg ccttaaattt aggagctgga ttgttaccct taaactgtag
    42961 atgggcaaca aactgaccct ctcccttaaa ctgatgaggg tacatccgag ccgtttctgg
    43021 caggtcaata ccagctacca ttccattgat atgctctact ggcaacaagt caaaatcata
    43081 ctcttccagc aaccaattga caatctcttc gttttcctcg ggtgcccagg tacaggtcga
    43141 ataaaccaga cgaccacctt cagctaacat ggtcactgca tcctccagaa tttctctttg
    43201 caagctagca cattgactcg gataatctaa gctccaatag tccatagcat caggttgctt
    43261 acgaaacatt ccttcaccag agcaaggggc atcaagaacg attaagtcaa aatagccttt
    43321 aaagaccttg accaagcggt cggcagattc attggtcacc acgacatttg tcgctccaaa
    43381 acgctccatg ttttcaacca aaatcttagc ccgtttgctt gaaatttcat tggaaacaag
    43441 tagcccctcc cctgctagat aggctgccag ttgagttgat ttgccccccg gtgcagcagc
    43501 caagtccaag accttcatac caggactggg ttgggctact tgagccacca tttgagcagc
    43561 aggttcttgc gaataaacta aacctgtagc atgctcaggc gatttccctg aaaccttccc
    43621 atagtggccc caaggggttt gagtaatggc atcagaaaag gaaagttgct cttcttttaa
    43681 gggattgacc cgaaaggccg aaaccgcttc ctcctcaaaa gaggcaagaa aatctcttgc
    43741 ctcatctcct agtatttctt tatatttttc aacaaatcct tctggaaatt tcatttaagt
    43801 tcttttcctt tcgtaaatat aggactgaat ttcctcctgc atctcaagag gcaccatcat
    43861 gaccggctgt ctggtttgaa aatcaggagc ttcaccaaaa agggtcacaa cccgatagcc
    43921 cagactttcc cctaaaatac tagctgcggc ataatcccat ggttgcagat aggtgagata
    43981 ggtcaacaaa cgccctgaca aaatcttggc aaaactaatg gccgcacttc catagacacg
    44041 aacaccaaga accgctcggc tcaaatcagc cagcccccat tcattggttt ccagcatacc
    44101 actattccct gcaatgagaa aatctccaag tggtttagtt ttaaaagaag ctaggggcct
    44161 atcatttaga caaactggaa attccccacc accgtggtaa caatcccctt tgaccacatc
    44221 ataaatcaga ccaaactgtc cctgaccatt ttcaaaataa gccatcataa cagcaaaatc
    44281 ttcctgctgg gctacaaaat tattggtacc atcaatggga tcaatgaccc aaaccttgcc
    44341 ctcttgaacc gaggctcgca gacaaccttc ttcagcacaa atcttatcct caggataacg
    44401 ggacaaaatc tcaccaacca agagttcctg aacttctttg tccagtctgg tcaccaaatc
    44461 tgttggagag gacttggttt caacacgcaa gtcttcctgc atatggtcaa gaatgtactg
    44521 acctgctttc ttaacaagct ctttagcaaa ttcaaattta ctttccaaga gaaatctttc
    44581 cttccccttt ttctttggca gcctgaactg ctcggtaaag tgaatagcca ctaaccgttt
    44641 caaattctcg tcccaaacgt ttctcttcgc tcttgcttgg cacgaccgct ttgaatccct
    44701 tataggagtc cagtaacttt ttagcctcta ctttgccttc ataggcagct tcaacatcat
    44761 taaaaaaaga aagcactgaa gcaagttctt cagtgctcca cgacaaatct agtgggtaac
    44821 tatactgttt gttcattaac taataccagc tctcattctt gcttctttta gttcttgctt
    44881 acgataacta cgagggagaa aagcacgaat ctcatcttca ttaaaaccga tttgcatacg
    44941 cttggcatca ataataattg gacgacgcaa aagactagga tactgctcaa tcaaatgaag
    45001 caattccgat accgaaatac tctctacatc aatattcaat ttttgaaaaa tttttgaacg
    45061 agttgaaatg atgtcatcag taccattttc ggtcaaggaa aggatttgtt gcaattcttt
    45121 tcttgttaaa ggactggtca taatattgtg ttccacaaag ggaaccttat gtttttctaa
    45181 ccaggcctta gccttacgac atgatgtaca gctcggtgat agaaatagtg taatcatgct
    45241 tttctcttct tatctatact ttgctacttc tattatacaa aaaaataagg cgcttgacta
    45301 gggattttta gaaaaaaaag cctatttttc aagaaaaata ggctgtttgc gaacgattga
    45361 cacaattgga tttggttaat tcactcttaa cgatggtttt aaacgatata tatttttata
    45421 tatgcaaatt aaaaacatct ttcatttcat ttcctacgac ttttcagaca cagatagcca
    45481 aagaagcttt catagagggc aaaaaagagg aggaaggcat gaagaaagaa ggtctctggc
    45541 aaaatcataa taacaggatc cttggctgga tcaaaaagcc aggtatcatc tcccacaaag
    45601 agaatttgat ggaaaagagt aaagaattgg tcaaaaccaa tcaaaactcc cccaagtcca
    45661 atcatcacag gtaagactac tagagtcagg agactttttc gataaagaga caaaaagtcc
    45721 tttttcacaa ttctattgac aaagacatag aaacttggca gtgtcactag agctactagc
    45781 tgaaccaaat gaaagagatt cttgaccact gcgaaatggt gcagaccagc tgctgacgaa
    45841 cgaaaatcag gcatctgtaa gacctgacta aaaggattgg tcagataatt catcaagata
    45901 tgaaaattgt attgaatggt ttctggtttt agatagactc gattcgttaa gtttagccac
    45961 tgaatctcca taggatagaa aatccaagcc agataaatgg tcagaaggat tgagagggag
    46021 aggagaaaga gcatagagcc ccaaaaggtc aatttagttt tcatcaaaat cccactccgc
    46081 aaggctagaa accacatgtg tcggtgcgat tggcaggcca gctacttctt ctgccttagt
    46141 aaaacctgtc gtcaccaaga gcgttggaat gccattgtca atcccagccc ggatatcagt
    46201 caaataattg tccccaacca tgattaactc ttcacgttcc aaacctaagt gctcaaccgc
    46261 cttgtccata atgatggcat tgggttttcc gatataaacc ggcttcactc gtgtcgctac
    46321 ttcaagcagc gtaatcagtg agccagcacc tggcaaaaga ccgcgttccg tcgggatgtt
    46381 gaggtcagga ttggttccga taaaatgggc acccttttga atagcaagag ttgctgtggc
    46441 aaatttttca tagtcgactt gccaatccag accaactacc acgtaggcag ggttttcctt
    46501 gtcttccaca taaccagccg ccttgatggc ttccttgagt cctgcttctc cgacgacata
    46561 gacggtcttt tcaagcccca aatcattcat atagtcgatg gttgctaaag tcgctgtgta
    46621 gacagtcgat aggggcgtat cgatattaaa attctgagcc aacatctcct taacactctc
    46681 tggagtgcgg gttgtattgt tggttacaaa gagataggga atgtcccgct tttgcaattc
    46741 atgaacaaaa gtctctccag cagggattcg gtctttcccc ttataaatgg ttccgtctaa
    46801 atcaattaaa tagcctttat atttcatcta tttctcccta agcctttttt atttcttgcc
    46861 aagtaatgat tgcttgggca ttgataaccc catcacttgt aatttcatgc ttgctttcca
    46921 gtccagtccg ttcaacagcc gatgtaatca ccccacctgg tcgaacttcc ttgacatact
    46981 tgaggttgat tttcttggga atatagtggg tcaaaaaatc cgctcccatg acctcaaaaa
    47041 tccagtccaa gtatttactg ttattgacat gaccattcat atccaagtcg taaaaacgaa
    47101 catggtaatc cttgctgatc ggctcttcca aggattcata cttcggtcca cggataagtt
    47161 ttttatcaaa atcagactgg taaggagcca caatctcagg ttcaacaaca tggacttttc
    47221 gactgtcgcg gtccatgaga acaaaggtcg ccatcatgtg gatgagctcc tgccccgctt
    47281 cattataaat agtaaagcga cggtagcaaa aaagtcgatt gtagctcaag gcttccgttt
    47341 cgatggtaat ttcttccgca aaacgaggca aacgaaccac ctcaatatca tattctgcga
    47401 taatccagac cagattatag tcttccaaaa tggccttatc actaactccc agttcaatcg
    47461 attgcatccc tgaaacttgc agtgacagca aaatcacatc tggaagtttg atatgaccgt
    47521 tcatatcagc catatcaaaa ggaattttca ttttcatttg ataagttaag cccatgatcc
    47581 tactccaaaa taaatcgttc tgctacagta tctcccaaaa agagacctct ctttgtcatg
    47641 cgaacgtggt caccctcaat ctgcatgagg ccttgttgaa ccaagtctct gacaatttct
    47701 ccataaagtc cagcaaaaga ctgtccaaat ttttcctcaa atcgcgccat ggaaaccccg
    47761 gatttcttgc ggagtcccaa gaacatttct tcttccattt gctccttttg actcaggtga
    47821 tcttctgtaa tacaagcatt gccttcctca accgcactga gataatgacg aatgggacca
    47881 taatttttat aacgtactcc attgacataa ccagatgccc ctgcaccaat accatagtat
    47941 tcagcattgt cccagtacat gagattatga cgactttcaa agccgggttt ggagaaatta
    48001 gaaatctcat aatgctcaaa acccgctcgc tccagctctg caatgatgta ctcaaacatc
    48061 tccgcttcta gttcctcctt aggcagaggc aatttcccac gtcgcatccg gttcataaag
    48121 accgtatggt tttctaaaat caaactatac aaactcatgt ggggaatatc caatccaatg
    48181 gctttagcca cattttcctt tacttgctcc atggtctgac caggcagagc ataaatcaaa
    48241 tcaatggaga tgttgtcaaa accagccagt ttcaggcgat cgatattttc ataaatatcc
    48301 ttctccaaat gactgcgccc aatctttttc aacatcttat catcaaaggt ctggacacct
    48361 agcgaaacac gattgacagc cgaatttttc aaaacagcta tcttatccgc atccaaatcg
    48421 cctggattgg cttcaatggt caactcttcc aagacagaca aatccaagtt tttagtcaag
    48481 ccattcagta acacctccag ttgcggagcc gacagggctg tcggtgttcc accaccgata
    48541 taaagggttg acaacttttc aatatcataa gaacgaaact cttccagcag atgctctaaa
    48601 tagctgtcga ctggctgatt tttgatgaag acctttgaaa aatcacaata ataacaaatc
    48661 tgggtacaaa atgggatgtg cacataggct gacgttggtt ttttctgcat agtaattatt
    48721 ataccacaaa gactagattc cagataaaaa tcaccatccc cagatacata gtccgttcgg
    48781 agatggtgat ggtttattct tctgttatat caatcacaat ctcttctgag tcatcaagag
    48841 cttcggcttt ttcttgccat tgttccttga gattatttaa ttgatttttt gatgcttctg
    48901 tcgcttgaaa agcataggat ttagcttgag caagtatact gtccacagtg atttcacctg
    48961 actcaacctg ttcttttgtt ttcagaacaa aatctgtagc ctgctcctta acttctgtca
    49021 gtttttcaca gacttgctcc ttggcatact ccggatcttc tctcaaatca tctagaaaat
    49081 cttgagcctg actgcaaact tgtttgccct tatcacttgt taaaaacaag gcaagagctg
    49141 cacctgaaac ggttcctaaa aggattgagg ataatttacc cataaggatt ctcctttttt
    49201 attttttgaa aaatttactt gcaagacgaa gagctgacag acttgcacca gtcttgagtg
    49261 tttttgaacc agctgatgaa gctttcttgc tcaagacacg cgcatggtca ttgaggtctg
    49321 aaacagatag agataaatct gcaacagcac tgaagagtgg atcaatcgta gccaccttga
    49381 cattgatatc atctgccaag acattgacct tagccaacaa ctcattggta tgatgcaagg
    49441 tcacatccac atctgaagtc aaggttttaa tcgtcttttc tgtttcatcg atgacacgac
    49501 caagcttttg tacagtaatg atcagataga ccaaaaagac aatcaaagct agggcaacaa
    49561 gaatatatgc aacttctaac atttagtttt cctcctctgt aatatagtaa ggggccttct
    49621 ttcgattttg ataaataacg atcattatac cgagaccgat aaggacaact gacagccatt
    49681 gggacactcg aaggccgaag aacatgagac tatctgttcg cataccttcg atgaccatac
    49741 gaccgaaacc ataccaaatc aagtaaaagg ccgtgatatg acctcgtctg agactcttcc
    49801 atttccgtct aaaaatcaga atcaaggcaa agccaagcag attccataga gactcataaa
    49861 ggaaagtcgg ttgacggtag ctcccctcaa tatacatctg gtcacggata aagccaggta
    49921 gataatcaag attatccact gttgcaccat aagcttcttg gttaaagaaa ttaccccaac
    49981 gccccaaact ttgagcaatc ataacgctag gcgccgcaat atctagaaaa tcccaagtat
    50041 tgatgagttt acggtcagca aagatataga gcacaagagc cccagttatc aaaccaccgt
    50101 aaatggccaa accaccattc caaatggcaa aaatctctcc taaattctga ctatagtaat
    50161 caaatcggaa aataacatag tagagacgag ctcctaaaat agccaaggga aaggctacta
    50221 agataaaatc taaaatatcg tctggtatga tcttctttct aggtgcttct ttcatggtca
    50281 aataaaccgc aagaatcaag cctgtcacaa tacataaggc ataccaacga atggctaggg
    50341 gtcctagttg aatagcaatt ggatcaagca ttttgcacct catttcgagc gattagactt
    50401 gtcagtcgtt cgtcgaacaa acgggtcgca tcaaagccca tttccttggc acgataattc
    50461 atggcagctg cctcaatcac aacagagata ttacgacctg ttttaactgg aatacgaata
    50521 cgaggaatgg ctacgccaga aacttcaagt tcctctgcat tgtttccaag acgatcaaag
    50581 gtcttatgtg tatcgtaatt ttccaaatag acagcaagct gaacctgtga agaatccttg
    50641 acagcactcg caccgtagag actcataaca tcgataatac caaccccacg aatttcaatc
    50701 aagtgtttca aaatttcagc tggttcaccc cagagagtaa tctcatcctt ggcaaagata
    50761 tcgacacggt catcggctac caaacggtga ccacgtttga caagctcaag acctgtctcg
    50821 ctcttaccaa ttccactatc tccctgaatc aagacgccca tcccataaat atccatcaag
    50881 acaccgtgca cactggtacg ttctgccaaa cgagaatcca gatagctaga taactctcca
    50941 gataaacgac tggtagctgc acggctggtt aaaatagcaa tcttacattc tctagcagcc
    51001 tttaacatct cctctggaac caccaaacca cgggcaacaa tgactgctgg tgtctcaggt
    51061 agaaacattt ttttcaaaac ttcataacgg ctgttggaag gcatgctgat cagataagac
    51121 cactccttca tccccaaaag ttgaatccgc tctggtgtat agtagtcaaa atagcctgtc
    51181 atttcaagac caggtcgcgt aatatccgct atattgattt ccttttcaag caattctggt
    51241 tcaccataga caatgtctag tctaagcttt tcaatcactt cttttactaa aaccgacatc
    51301 atttcctcct tcaaatgagt tcttctctct attatatcaa attgtaggag gaagtttcag
    51361 atttttgcag gctttggagt atttatttaa aagaaaaagg actagatttc tctagccttt
    51421 cattccaatt agaatttttt acgtttacga gctacttctg atttacgttt acgttttaca
    51481 gaaggttttt catagaattc acgtttgcgt gtttcttgaa gagtaccagc tttagtaacc
    51541 gcacgtttga aacggcgaag tgcgtcgtca agagattcat tcttacgtac tactgtttta
    51601 gacatttttt tcactccctt caagttcaat atctatttca ttctacacgt aaaaggaata
    51661 attgtcaagc aaaaatgcgg tttaattttg attttttctt ccatttatac aagagttgaa
    51721 agcgttcaat agaacattgc ttttttattt ttcgagtaag ctaagcgctt cagcatctgc
    51781 gatgatggtt acatcagggt gattttggag gctacttgca ggtaggttct cagtcactgg
    51841 gccagatact gttccggcaa tggcttctgc tttcgactca ccgtaagcaa aaagaataat
    51901 agacttggca tccaaaatgt ttttaatccc cattgaaata gcttgggttg ggacgtcttc
    51961 aatcttggca aagaagcgtg cattggcttc aatagtagac tggtcaagtt ctactagatg
    52021 cgtttgactg tcaaatggag taccaggctc attaaagccg atatgcccat tgcgaccaat
    52081 tcccaagatt tggaggtcaa ctggatggtc agccaaaatt tggttgtagc gttcaacttc
    52141 agcttcagca ttgtccttaa caccacgagg caagaaactt tctttaaatg gtttttggtt
    52201 gaacaagttt tcttgcatga agtaacgata agactgtgga ttgtccccat caaggcccac
    52261 atactcatca aggttgacac tggttagatt tgaaaaatca aggtcactct caacaatttc
    52321 cttgtaaaat tcaagtgggc tacttcctgt cgcaagtcct agagtttgag ctccattagc
    52381 caatttttcc ttcaaaatct caaaagcaac ttttccacct tgaacttggt tttcaacttt
    52441 aataactttc atcttttcat cctccatttc tgtctatatt tattatatgg tatagaccaa
    52501 tttttgtcaa gtgaaaacga tttaatttct aaaaaaagag cgtccaaact tgaaacgtgt
    52561 tataatggat aggattataa cttagaaaga atgaacaaat atatgaatac agctgatttt
    52621 gatttccact tgccagagga attgattgcc caaacgcccc ttgaaaaacg tgatgcctcc
    52681 aaactcctca tcgtcaaccg tgagacagga gaaatgcaag ataaacattt ccactctatt
    52741 attgatatgc tggaacctgg tgatgccctt gtcatgaacg acacccgagt tctccctgcc
    52801 cgcctctatg gtcaaaaaat ggagacagga ggtcatgtgg aacttctcct ccttaagaac
    52861 actagtggag acgagtggga agttctggct aaacctgcca aacgcctcaa ggtcggtact
    52921 cgtatcagct ttggtgatgg ccgcctcagc gctgtcgtta cagaagaatt gacccacggg
    52981 ggacgcattg tccgctttga ataccaagga attttcctag aagtcttgga aagtctggga
    53041 gaaatgcctc tgccacctta tatccacgaa aaattagatg accgtgaacg ttatcaaacc
    53101 gtctacgcca aggaaagcgg ctctgctgca gcaccgactg ctggtcttca cttcaccaaa
    53161 gaactgctgg cagaaatcca agctaagggt gttcatctag tctatctgac tctccatgtc
    53221 ggactcggaa cctttagacc tgtttctgtg gataatctgg acgaacacga aatgcactca
    53281 gagttctatc aactttctga ggaagctgct gccacccttc gctctgtcaa agaaaatggt
    53341 ggtcgcgtca tcgctgtcgg aaccacttct atccgcacct tggaaactat tggttccaag
    53401 tttgatgggc aaatccaagc agattctggt tggaccaata tctttatcaa acctgggtat
    53461 gagtggaagg tcgtggatgc cttctcaacc aacttccatc tgccaaaatc aactctggtc
    53521 atgttggttt ctgcctttgc aggccgtgaa ttagtcttag atgcctacca ccatgccatc
    53581 caagaacact accgcttctt cagttttggt gacgccatgt ttatttattg agaaagaatt
    53641 tctctaattc ttctaatacc aataaatcgc taagatatta tttcaaagaa catctacaat
    53701 tgaaactcta gctagctgta gaagacgcct agtacattga aattaaaatg cttcccccta
    53761 gcttcgaaaa tattgccata gattgcgttg actctccaaa ttgattcatc tatattttat
    53821 ttcagcttcc tatattttct tcgctgtttg taaatcaaaa tgcaagacac atgagtagca
    53881 ccatatttgt tactcttatc tgtcctctca agagactatt atgagttatt tcagaatcat
    53941 tcactacttt gaccctgact ctccttagtc tcaaaatcaa agacttatac tcttcaaaaa
    54001 tctcttcaaa ccgcgtcaac gtcaccttgg attatatatg tgactgactt cgtcagttct
    54061 atctacaacc tcaaagcagt actttgagca acctgcgact agttttctag tttgctcttt
    54121 gattttcatt gagtattaaa caaaaagtga acaaatctga attctaatgt acagaagact
    54181 aggcttgttc acttttttat agtcgctata agatgacctt atctatagct ttttatatat
    54241 aattatatat tcagacatac tattatcaat tttgtcgcag ggaggaatct gttaacgcac
    54301 ccattcacca ttatcattga ctctatagcc atctatactt gtattgaccg ctaactcacc
    54361 cgatgcattt acataatacc atttaccacc aacttggaac cattgattga ctttcataga
    54421 accgttgctg ttgaggtagt accatgaacc attaacttgt acccaacctg ttgccatgga
    54481 accatcagta ttataaaaat accacatacc attttcttgt ttccagtctg ttgttggagc
    54541 aactgcttta gctggttcta ctgctacatc tgttccttgg ttagatgtaa cagatacagg
    54601 atacgaagga atagatgatt gctcaggaac aacaactttt tcaggttctc tcgtccctct
    54661 ccttatacgt ctttttacca tctctttagt aatttgacga gaagtagttt cttcaattgt
    54721 tccatcacgt tcatctacag tatagattgt agtaagagta atttaccaat ttctcctact
    54781 tcttctactt cttgactttt atcaagagtt gggccatcga gatattctgt ttcgattgga
    54841 atttcttgga caagaacttg gggcttggtt ctttttttaa caactcttgt ttgagagtct
    54901 ttttttgact taaagtactc tcagttactt gtccactctt tccatctaca ttataagtta
    54961 tcgttgtaac tgttttccca ttctttccta gagtaatctc ttgctcctgt cctgcagaaa
    55021 ggtcattgtc tgcttcatat ttagtagcaa atggaacaag aacttcttca accttgcttt
    55081 tagctggaac tttgataact gtatccgtgg cttcttttct atcaacagta acctgttcgg
    55141 taacataacc agtctctgga ttaacatcgt aggtccttgt cgtagttaca tagccatcct
    55201 ctccatcaat tgtaacagga ttttcactac ggtcttttgt ttcatctttt tcataacgaa
    55261 ttcgcgtact tgaaattttc ttggttacta ccttaggttt agtcgctact tttacaataa
    55321 tatccccatt gtcagcgtca tcatactcta ttccctcttc tttatctcta gtatcatctc
    55381 tgacatattg aatcccatca gcagcatgaa caaaacttgt attcagattc ctcctaaaaa
    55441 taaagttagc ccgattaccg cagaaccaaa aatctttccg agtttacgta ttgcatagcg
    55501 cttattagta ttagattttg ccattacatc ctacttctag tatagcatct tttctatcaa
    55561 acgttaaaca atatacttta tatataaaat agacttagaa tgatatattg attattgaac
    55621 taacacttta actatatcgt aatcaatctc atatataaag gattgcagac atcttatcta
    55681 aatacatgct aatatattta gatacaaaca ttccaacttg ataattttca ctcatctttc
    55741 atcattcctt atacaactat gcagtataaa tagaatagtt ttctcatcag aatgagacta
    55801 ttttaatatt agataatttg atagaaaaaa catgaataaa attggttgaa tttaattccc
    55861 taactcgata gaggattcta ttttaaattt aacaacagct aggattacac tataaaaagt
    55921 acattaccac ctgttcggct ggagaatcta gtcgattagc tccctcttag ttacaagctt
    55981 caagcgattt tttaactaac actaaaccag attaaagaag gaactagaac atctgtcttg
    56041 tactaatcaa tatgctattt taaagtttca aataaacttg gaatgctaat tattatattt
    56101 acaataaata gttgacttcg atagaaacag aaaatagaat tcaacattct tccctactta
    56161 taccataata aataagatcc gcaagatagc cttttctctc tacaccatta acaatggttt
    56221 gtagatagga cattccagcc ttttccatga cacgacctga agctgggttg agactggcat
    56281 aacgtgctct gaccttttga aaacctgctt gagtaaaaca aaagtccaag atagctttca
    56341 aagtctctgt catcatacca tttccccagt aagccttgcc taacacatag ccaatttcac
    56401 agcttaaatc agcctcgtct atcttaacaa tgctgatatc tcctattact tgctctgggt
    56461 tttcttttag acaaatggcc catttataat agttgagatt agtataggaa gcaacccaat
    56521 tgcaaatcga gtttcgagtg atttcgacat caggatgggg atcccaggta acataggtca
    56581 gattctcagc ggatgaagcc caattttgaa acatggcttc tgcatcactc tccacaaatc
    56641 ttcttaaaat caaacgttct gtctgtaata tttgcgtacc gatagatttc atgatgctac
    56701 ctcacttcct tatttctata ctcgtagtaa aaaggctcaa ctcagtaaca gctagaaaac
    56761 gagtttgtct tctaatttct tgacgcagtt gctgcctggt ttgaaatgcg ctctagcaag
    56821 ctttttcaaa cctagtcatc gttgcagggg taagacgatg aaatcgaact cttcgagtta
    56881 ctgaatctgc ctcattttct tatttctaaa ctcggggttc aagatccccc agaccttctc
    56941 tcactttctt atttcaagat gagaggctga aaacctccag tggaggtttt tcttgctttt
    57001 taatttcagg gcaagaagct aaaaaggtcc cccggacctt tttactccca aaagtcatca
    57061 aatacggtga tgggtaagtg gcgtttgtgt tggcctttgt gccaccagtt ttcaatggtc
    57121 gcttgagctt ctgggctgat tgttttgcct tctaggtagt cgtcaatctc tgcgtaggtg
    57181 actccaagtg cgacttcgtc agctaggcct ggtttatctt cttctaggtc tgccgttggg
    57241 attttttcat aaagggctgg ctctgcgcca agtttctgca agagctgttt tccttggcgt
    57301 ttattgaggc ggtaaagagg gagaatatcc gcaccgccgt caccaaactt ggtaaagaaa
    57361 cctgtgatat tttccgcggc gtggtctgtt ccaatgaccg ctccgctatg ggaaccagca
    57421 agggcatact gagcaatcat acggcaacgt gccttgatat tccccttgtt gaagtctgaa
    57481 acaggactac ctgtcgcttc aactgcagct gtcatggcat cagctgattc cttgatattc
    57541 acaaccaagc tgacatctgg ctggatgaag gctagggctt tttgagcatc tgcttcatca
    57601 gcttgcactc cgtatggcag gcggacagcg ataaatttgt agctatcgtc tcccgtttca
    57661 gctcgcagtt cttccatagc taattgcgcc aaacgtcctg ccaaggttga gtcttgtccc
    57721 ccagaaatcc ctagtacaaa ggtttttagg aagggatgtt ttttcagata tctttttaag
    57781 aaatcaatag aacgacggat ttcttcctgg gcatcaatca ctggtttgac acccagctct
    57841 tggataatcg tttcttgcaa actcattctt cttctccttc accaagggct tccttgcgca
    57901 tcttatcaat caagtccatc ttatcttgcc atacatcacg cgccaaatcc actggatagt
    57961 gctgcggatt gagcacacgc ttatactcat cccacaactt gtcaaattcc ttacgggcat
    58021 aatcctgaat gtcagtcaaa ctaggcaagt tgtaaactaa tattccttct ttgaagatat
    58081 ccaccaagag aggaacggca tcaaaattac gaaccgtctt cttgatgtat gtataggtcg
    58141 gatggaacat cttgatttct gtcatgtcgc taatatccac accatcataa gtgatatagt
    58201 cgccttctga cttgcctttt tcacgactgg taatgcgcca cacctgcttc ttacctggcg
    58261 tagaaacttt ttcagcatta ttagacagct taatcgtatt gcgcatctga ccagtttcat
    58321 cttcgattgc aacaatcttg taaaccgccc caagagccgg ctggtcatag gctgtaatca
    58381 gcttggtacc cacaccccag acatcaatct tggccttttg catcttgagg ttaaggatgg
    58441 tattttcatc tagatcatta gaagcataaa tcttagcctc tgtaaatcca gcctcatcca
    58501 gttgctgacg gactttctta gaaatgtagg caatatcccc agagtcaatc cgcacaccca
    58561 taaagttaat ctgatcaccc agctcacgcg ccacctgaat ggcagctggt acaccgatgc
    58621 gaagggtgtc ataggtatcc acaagaaaga cacaattttt gtgggtcgca gcgtaagcct
    58681 tgaaagcttc atagtcattg ccataaacct gtaccaaggc atgggcatgg gttcccaaaa
    58741 caggaatgtc aaagagctta cccgcacgca cgttgctagt tccattggcg ccaccaatca
    58801 cagctgcgcg tgttccccag atggccgcat ccatttcttg agcccgacgt gtcccaaact
    58861 ccatcaaggg ttcatcttcg ataaccgaac gaatacgagc tgccttcgtc gccaccaagg
    58921 tctggtagtt gacgatgttc aaaagagccg tttcgaccaa ctgacattgg gctagaggtc
    58981 cttccacctg cacaatcggt tcattagcaa aaaccaaatc cccttcttgg gcagaacgaa
    59041 cggtcaactc caacttgaaa ttgcgaaggt aatccaagaa cgccccatga taaccaagcg
    59101 actccaaata ggctatatca ctatctgaaa aacgcaagtc ttcaagatag ttcacaattc
    59161 tttccaaacc tgcaaaaacc gcatagccgt tcttaaaagg ctgttggcgg aaatacacct
    59221 caaagaccgc cttcttattg tgaatccctt ggtcaaagta aacctgcatc atgttgatct
    59281 ggtacaagtc cgtgtgcaat gtcaaactat catctggata catacttttc ctacttcctt
    59341 agctagaaac ccatgaaaat tttcaagaac tttcatgtat tccaataaat tagtactatt
    59401 atatcacatt ttagctggat tgagaaaaga gtaacaagct attctccact ctccaattca
    59461 tccatatctt gttcaaattt tttctgagcc cattcgccat agctcttaag accaagattg
    59521 ccaataaaga tccacggaag gtaaatgata taagtaatga cccaagcaga caggtattta
    59581 aaattcaaag gattgtgctg ataaatttct atgttgaatt gataattctg caacatcaaa
    59641 agagccgtaa tagccaaggt taggaaaaaa caacccaaaa tcgtaaaatg aaaacgacta
    59701 tagtaggtca ctcccagata acgggcacga ttgaaaaagt aaaatgtccc tatgatgata
    59761 acgattagca gcatattaga attaaaaagg cttggtgcta atactgaaat gatataagat
    59821 aggagcgaca aagcgatgca gatatagaaa ctttcagagc ccgctttatt gaacagttgt
    59881 tcttctcttt cgtctagtaa ttgataataa taaaatctat ttttcatctt cttcctccca
    59941 aaatagttgg tctagggttt tccctaaaca tctgcaaatg gactggcaga gcgagagact
    60001 gggattgtat ttccccgctt ctatcaaacc aatagtctgg cgcgtcaccc cgacagcctc
    60061 tgccagttga ccttgtgtta aatcacgctc tacccgagct aattttaatt ttaaattttt
    60121 agccaccttc gtcctcctta tagttttaat actcatctac tcttaaaaaa tccaaaacca
    60181 acacaagcta tcagctattt attataaccc cattaatttg cactccagta ttatcttcag
    60241 ccgaaaatca gtattttagg ttgtttgaaa taaacttcct agtttactct tttattttta
    60301 tttagtatta gctttagtag gatcttttaa acgagttttt attgcttata tttcttgttt
    60361 agtttagttg gtttcatatc actattatat aatgcttttg gaaatgagcc tagtataagt
    60421 caaaaacgtg ttgaatagtg aaagcaggag cataccaaga tgactgattt ttttattgta
    60481 ttttaggtat gcaaaataat actaaatgaa actaaaatga atacttcttg cttttcttga
    60541 gagtgaaaaa gtacaataaa atgattgtag tgattagcac aagatactga ctaatagaca
    60601 tcgtatttga agccacaaat acaggtaaag aataaaaaag gaagaagttc aattgctttg
    60661 ataaacaaat cattactagt attcatcatc atcgtattta atatattaga gataaagagt
    60721 agtaaagcta ctaaaatacc aaataccaag ccacttttca atttgtataa atagaaaatg
    60781 taagataata gaaaataaaa caggactaac aaaattgtat tgactacaat agctactata
    60841 aaatttaatc ctaaatcacc tggaataccc aatttactta ctatgactag taacacaatg
    60901 ccattcaaag cataaataat ggaaactgag atagcatata gaaaattaga caagacgtaa
    60961 atcatccgat tcttctgttt atttaatttc atgattataa ccttccttta ttttgaacga
    61021 tttaggtaaa tatctttaag cgtctctttt ttagtttcaa aatcaactac tttaatagag
    61081 ttttcgttaa aaaatttaaa aagctcacta ttttgaatat tcccagacat agtaattctc
    61141 aatccctctt cctaaacaat atcccaaaat tcttgtttgg taatgaaaat gtctctatct
    61201 gtagctgatg aaaaagctat ctcaaacaag aaattatgac tatcttttcc tactttttga
    61261 aatgtcaaaa gcccgttctc caagaaaaga actctctcac aaatttcttc aatgtcttct
    61321 aatttatgac tcgatattaa aattcccaca ttttcatgta aagctaattt ttttagaacc
    61381 gctaaaacta tttgtgatga ttcaatatct aaaccattag tcggttcatc taaaatcaat
    61441 atatcaggtt ccgtaacgag agttagaagc aaagctaatt tttgttttgt acccaaagaa
    61501 taggtcttta cttttttatt aatagactga gtcaaatcta actcttggat caaacatcta
    61561 aatctttctt gattgtagtc aacaccatat aaatttgaca aatattttaa attctctaaa
    61621 cctgttttag ataaaaataa ttttggttct tcgattaaat acccaacatt atcactgctt
    61681 ataatattac ctgaagtcgg ttgattattc tgaacaagaa ttttcatcaa cgtactctta
    61741 ccaactccat ttctccctgc tagaccaaca atttcaccct tgttaagtgc aaaatttata
    61801 tctttgagaa tgattgaatg accataatgc ttacttacat tttttattcc tccattaata
    61861 ttattggttt tctctttgat tctcattaat tttaaaaagt tgcgcctctt tttaacaata
    61921 ttatatcata tatctaactt aatgcaatat ataaatgtca ttttgtgaaa ttttattaac
    61981 aaaaaactct ctacaacaaa ataatagaga gttttctgct tattaatttt tttcaaaata
    62041 tctaagacat cacttctttg tttaatttga taggctttga tacctgagct ccgactttat
    62101 cacttaaaaa ataaaaaaga cagctaatct cttgcgcatc aagggatttc gccattcttt
    62161 aatctcgttt aagtgttgta tatggagctt tgcataattt tttaaaacta aacaactaca
    62221 ttaagcacga actgtgacgc tggttccatc ttccttataa agattgataa gcccctcttt
    62281 aagagctcga accatgtctc cagcttgaac aggttgtggg actttaatag tcaatagttc
    62341 cattggattt ggagcgcggt cgattttatt gcctttggcc tcatgcaaat cttcaatata
    62401 ggtttcaaaa tgacggaaac ctggaccata aaactcaact tggtcccctt cgttaatgac
    62461 gttccgttga cgaatggttg ctgtttgtgt cgcatcatca taagaaatca cttcagcgac
    62521 aaacttgtac tcaggaattt tacgacgagc accaaacaac tgctcatttt cagatggtat
    62581 accatagtaa aatcctgtag ccagttcacg ttgggcaacc ttccacatct cgtccaccaa
    62641 gtcttgtttg atagcttcaa acttttcagg actttcaaga taggcatcca cagccgcctt
    62701 gtagcagttg gttactgttg atacgtagtg aatagactcc actccatacg tccttcgatt
    62761 tttagattgt ccacaccatt ttcaatcata tctggaatgt ggtcaatcat agacatgtca
    62821 acggctgaca ttgaaaattc ttctggaatc tcaccctgca aactcttacg ttctttccca
    62881 aatggcatat cgtaaaggtc gtatttccaa cggcatgact gagaacatcc accacggttg
    62941 gcatcacgca tactctagac ggattgtttt gacaattcta atcttttaga ctttgcataa
    63001 taactgttaa acagtcgaaa attaccccag ttttaacaag tagtcaaaat accagataaa
    63061 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
    63121 tatgcgtttt attgtgggaa gatttacttc attttctctt gaaattgagt tttctcctac
    63181 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
    63241 taaagcgaga aaaacaaaag gggcaactta aactttcttt atattgctta tatgttagta
    63301 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
    63361 caaaagggtg attttctaat gaatcatgac accgataaca agcataatac tttttacaat
    63421 catagcattg taaagcaata atatccagct tgctatggta atgaatgcat cttgtttgct
    63481 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag ctcgaactgt
    63541 gacgctggtt ccatcttcct tataaaaatt gatgagtcct tcttttaatg cacgaaccat
    63601 gtctccagct tgaacgggtt gtgggacttt aatagtcaat agttccattg gatttggagc
    63661 gcggtcgatt ttattgcctt tggcatcatg caaatcttca atataggttt caaaatgacg
    63721 gaaacctgga ccataaaact caacttggtc cccttcgtta atgacgtttc gttgacgaat
    63781 ggttgctgtt tgtgtcgcat catcataaga aaccacttca gcgacaaact tgtactcagg
    63841 gattttacgg cgagcaccaa acaactgctc attttcagat ggtataccgt agtagaaacc
    63901 tgttgccaat tcacgttggg caaccttcca catctcgtcc actaagtctt gtttgatagc
    63961 ttcaaacttt tcaggacttt caagataggc atccacagcc gccttgtagc agttggttac
    64021 tgttgatacg tagtgaatag acttcatacg tccttcgatt tttagactgt ccacaccatt
    64081 ttcaatcata tctggaatgt ggtcaatcat agacatgtca acggctgaca ttgaaaattc
    64141 ttctggaatc tcaccctgca aactcttacg ttctttccca aatggcatat cgtaaaggtc
    64201 gtatttccaa cggcatgact gagaacatcc accacggttg gcatcacgca tactcatgtg
    64261 gtttgaaaga gtacaacgtc cagagtatga aatacacata gctccatgga caaaggcttc
    64321 aatttcaaca tctgtacgtt tgcggatctc agctaattct tccattgaaa cctcacgcgc
    64381 taaaacgaca cgagtcaagc ctagctcttt ccagaactca agggtttcat agttagtggc
    64441 actggcttgg gtagaaaggt ggatttcaag gcctggtgct tcagtcgctg caatcataat
    64501 caaggctggg tcagatacga taactgctgc aatcccgata tcacgcagtt tacggaacca
    64561 ctcaccagca ccagcttcat ttccttcgtg cataaccata ttagccgcta catagacctt
    64621 ggcaccatac ttggccgcaa actgcacgcc ttcttccatc tgttcgaaag taaagtttcc
    64681 cgcacggcta cgaagaccat aggcctgacc accgataaag acagcatctg ctccatactg
    64741 aacagctacc tttagcttct ctaaagtccc tgcaggtgat aaaacctcag gacgttttaa
    64801 tgtttttgtc atgatttctc ctatttgcaa tataaaagtt tgacattttt ccttctcatt
    64861 ttatagtaaa taaaggataa aatcaagcct agacggattg ttttgacaat tctaatcttt
    64921 tagactttgc ataataactg ttaaacagtc gaaaattatc ccagttttaa caagtagtca
    64981 aaaagtctag aaaagtaaaa accagtatcc aaagatactg actcgtaaaa atacataaat
    65041 tagtccttag atgactactc ccactctgtt gctcctataa tggaaaagga ttgatacagt
    65101 ctagaatatc gcttttttat ttattattct gatataaaac tgttagaatt gattttttgt
    65161 tttataccca aatatgaata gagacgtagc taataagttg aataacatat ttggaaaaat
    65221 gagaaatagc aatattacta gaacttttag aaacaatcaa tatttaaaaa gaaaaagctc
    65281 aaagaattta ttaaaccatg ttataataga tatagctata attttattta taacaagagg
    65341 atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat attctgataa
    65401 cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata agagccatta
    65461 tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg atttgtatca
    65521 aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag ctgcagtact
    65581 atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc ctaattctga
    65641 aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac acgcatacga
    65701 aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac acactagaat
    65761 aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact atccaaatag
    65821 aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta ttggagggaa
    65881 atattatgga gattctgcct gggaagattt aagagcagtg accggtattg atttacttag
    65941 tattctaaca gatattgcaa ataaaaaaca ggggtaaaat caaaatgaca gtattaaaag
    66001 gagataactt agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg
    66061 accctccttt ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt
    66121 cattcgaaga tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag
    66181 aagaatgcaa aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg
    66241 caaatcatca tattagatta attttagata atatctttgg agcagatatg tttcaaagcg
    66301 aaattatatg gaactataaa cggtggtcta attcaaaaaa gggattattg aacaatcatc
    66361 aaaacattta cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt
    66421 attcttctac tacaaatatc gaccaaatac tagtggaacg aaaacgagat ggaaactcta
    66481 aaactatata taaagttgat aataatggta actatattct agcaaaagag aaaaatggag
    66541 ttcccctttc agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag
    66601 gttatcctac acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata
    66661 aaaatgatat agttttagac ccgttctgtg gaagtggaac tactttagta gcctccaaga
    66721 ttttgaatag aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc
    66781 aacgtctgga aaatgttata aaaacaagtt cagatttatt gaataaagga atcgaagcat
    66841 atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc
    66901 aaagaaataa aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta
    66961 taaaaattca aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta
    67021 taaactccaa aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat
    67081 ttgattttga tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg
    67141 aaaaatggtt aagtaaaagt caacagttac tatagtttgc aaattattta cagaaagaac
    67201 aaaaaatgct ctgaaacact gatttcaagg cattttttgt tagtttaaaa ttactcccat
    67261 tcttcttttc caaacataca atatatccaa aaccattcaa aatactagat tctatttttt
    67321 ataatatcac taaatccacc taattatagg acgttttcag atttttagtc ccgtcccagt
    67381 cccagtaccg gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa
    67441 aagcaaaaga acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa
    67501 aaagctttaa gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag
    67561 agagataaat attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa
    67621 atttattcag actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa
    67681 aaaattactt taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg
    67741 gacttcactt ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga
    67801 tgaatatcca acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt
    67861 ttcagctaca ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc
    67921 cttaaataaa ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg
    67981 atttacattc gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc
    68041 atcatcaatt tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat
    68101 ccattcattt gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt
    68161 taatatttcc attgccactc tttctaaggc ctttgtaagt attatttgat tcgattgaag
    68221 caaggttgaa taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag
    68281 ctctttttta aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac
    68341 aaaatcatct tttatattat caaaatcaaa agtacataaa gagtttgcgg taatagtttg
    68401 atacggatta aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata
    68461 gtctgacata ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat
    68521 atcgataatg aagctgcctc cttcataaaa ccaatatagg ccttctgcat aagttgaatt
    68581 ctcttttttc caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc
    68641 atctactttc atataatctt ttacaaaatc ataatatgac ataacacact atccctttta
    68701 gacaatattc caattagcct tattaattca aaactattgt attagtaatt ataacagatg
    68761 tataatagaa aagcaatgat agatattatc aattaagcga atttatatct aaaagggata
    68821 ttaaagaaag gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat
    68881 aagaaatatc ttggggtttt ggccataatt ttttctgcta tatctgctgc acttacagta
    68941 tatggatatt atttaatcta caaatttcta gataagttaa taattaattc aaacttatcc
    69001 ggtgcagaga gtatagcatt aaaatctgtt attacactaa caagtggagc gatattttat
    69061 tttgtctcag gaatgttttc acatatcttg ggatttaggc ttgaaacaaa tttaagaaaa
    69121 aggggaatcg atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt
    69181 caaataagaa agatcataga tgataatgca gcacaaactc atcaggtggt agcacacatg
    69241 attcccgata gttctcaggc aataatcaca cccgtacttg tacttgcact tggctttata
    69301 gtaagtataa gggttggcat aattttgctt gctcttacta taattggtgg cttaatttta
    69361 ggggcaatga tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta
    69421 agtgctgaaa ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat
    69481 gtagagtctt ttaaaagctt ttataaggcg ataaaagatt actcaaagta tgcttatgat
    69541 tattccctat cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt
    69601 gcaattttaa ttattcctat agtttatttt atgactagct tagctagcgc aaaggtgatt
    69661 ttacttgagc ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga
    69721 atgatgtggt actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg
    69781 ctttacgaag atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac
    69841 tataatatag aatttgagaa tgttagcttt gcttataatg ataaagctgt cattgaaaat
    69901 ttatccttta atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc
    69961 aaatcaacag tagcaaaact tatatcaggt ttttacaatg ttaataaagg aagcataaag
    70021 ataggcggga tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt
    70081 gtttttcaag attcaaaatt attcaagaag agcatttatg ataatgtagc tttagctaat
    70141 aaagatgcga cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata
    70201 ttagacaaat tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc
    70261 ggtggagaaa aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt
    70321 attatggatg aagcatcagc atctattgac ccagataacg agtttgaatt gcaaaaagct
    70381 tttaaaaatc ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt
    70441 aaagaccttg atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac
    70501 aaagaattaa tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg
    70561 aatgaatgga gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg
    70621 aggagcaaga aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat
    70681 gcttcctgcc atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag
    70741 caatggcttt tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc
    70801 tatcgaatac gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag
    70861 gacagcggag aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga
    70921 catttcacaa acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat
    70981 accaaaggtg ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg
    71041 caatgtcaag atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc
    71101 tttatctaaa aaatatcagg ttaatggaca gaatagatat tatgatgtct taagaaaaaa
    71161 ctcagaaagc tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc
    71221 gaaggatatt aaagatgact tatataaaaa aatggaagat agtgagagag tacacttaaa
    71281 ggcggaagta actacaattt taactttgtc tatatcttca atatttagct ttatatctct
    71341 tgctgttgtg atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta
    71401 ccttatagga tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga
    71461 gggcttgatg gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa
    71521 tcaagatcta caagaaggcg atgactatag cttaaaaaaa tttgatattg atctaaaaga
    71581 tgttgagttt gcctacaata aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa
    71641 gcagggagag gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa
    71701 acttatatca agactttatg attatgacaa gggacaaatc ttaatcaatg gcaaagatat
    71761 aaaagaaata tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt
    71821 tctctttaat caaagcgtta tggaaaatat tagaatcgga aagcaagatg caagtgacga
    71881 agaggttaaa agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa
    71941 aggtttcgat acagttattg gtgagaacgg agctgagcta tcaggaggag aaagacaaag
    72001 attatcaata gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac
    72061 agcaagcctt gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa
    72121 agataaaact gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat
    72181 agtagttctt caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa
    72241 atcaaaaatt tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta
    72301 ggaggactac aatggataat aaaaaattaa aagtaaaaga tttagtaagc atcggtgttt
    72361 ttggcgtaat ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat
    72421 tgttcttaat atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta
    72481 tggctaaggt tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga
    72541 tgtttgcagc tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag
    72601 cagaattaat tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg
    72661 caatcttcag cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat
    72721 atatggagtg gtctttgatg acgatgggaa aagattatgt tgatgtatta gaaaagttaa
    72781 taacttatcc tcacatggct ttagtagcct taggtgcttt cttaggagga attcttggag
    72841 catatatagg caaggctcta ttgaaaaaac actttgaaaa agcaggcatt gtataatgcc
    72901 tactttttct tcaaatgctc cctttaatcc caatccgatc tctaagatat tagtcgtatt
    72961 tatcacaggc ttaactgtta tgcatagcat aaacatccgt tttgagctgg caattgtttg
    73021 tcttattggt attttgcttt atttgaatgg atacaaaaaa acacttttca aatggattat
    73081 attgtgtggg atactttact ccttgcctaa ttttatggtg ttatctgaat taaaccctat
    73141 agttaagatg tttttgagta tacctattgt tattagaatg tttattttac catttatggc
    73201 agcaagcttt atgataaaga cctcggatgt aggcgcaata atttcatcga tggataagct
    73261 taagatttca aagaatgtat ccatacctat tgcggttatg tttagattct tcccatcttt
    73321 taaggaggag aagaaaaaca tcaaaatggc tatgagagta agagggataa attttaaaaa
    73381 cccagtcaaa tatcttgaat atgtttctgt gccactactc attatatcat ctaatatatc
    73441 agatgacatt gcaaaagcgg cagaaacaaa ggcaatagaa aatccaattg ccaagaccag
    73501 atacattcgc gtaaagatac agctaattga ttttgtttat gttttagcgg ttgttggact
    73561 tattgtggga ggcttaatat ggttgaaata aaaaatttaa gtcttgatta tggtgaagag
    73621 catatattag atgatatatc actatccata gccgagggag agtgcgtgct atttacagga
    73681 aaaagtggaa atggtaagtc atctttaata aattcaatca atggactagc tgtaaggtat
    73741 gacaacgcaa agacaaaggg cgaaatcatt attgatggta agaatataaa aaatttggaa
    73801 ctttatcaaa tctcaatgct tgtttcaact gtttttcaaa atcctaagac atattttttt
    73861 aatgtcaata cgacattaga attattattt tatttggaaa atatcggtct tgcaagagaa
    73921 gagatggaca ggcgtttgaa ggatatgctt aagatattcc cgataaaaaa tcttttgaac
    73981 agaaatatat ttaatctatc cggcggtgaa aaacaaattc tttgcattgc agcttcttat
    74041 atagcaggta caaagattat agttatggat gagccttcat cgaatttaga tattaaaagc
    74101 ataagtgttt tggcaaagat gctaaagata ttaaaagaga aaggtataag cataattgtt
    74161 gcagagcata gaatttatta tttgatggac atagttgacc gtgtattttt aatagataaa
    74221 ggaaagctta aaaaaactta tactagaagt gaatttttaa agctagataa aaatgaatta
    74281 aatgctttaa gtttaagaga taaagaatta agtaaattaa aagttcctta tttaaaagaa
    74341 ggtggagagt atcagataaa aaatcttagc tacaaattta ctgatgatga gtgtttaagc
    74401 ttaaaagata tttcattcaa gcttgggaaa atttatggca taataggatc caacggacga
    74461 ggaaaatcaa cgcttttaag atgtttaata ggtcttgaga aaaaatcaaa agaagaaatt
    74521 tattttaagg gagagaagct atctaaaaaa gaaagactca aaaactcttc acttgttatg
    74581 caagatgtaa atcatcaatt attcacagat gaagtattca acgagcttag attaggagta
    74641 aagaattttg atgaagaaaa ggcgaaaatc attttaaaag atttaggcct ggacgaattt
    74701 attgaaaggc atccgatgag tttatcagga gggcaaaagc aaaggcttgc aatagcatct
    74761 gttatgtgca agacttctcc atttgtcttt tttgacgaac cttcaagtgg tatggattat
    74821 tccaatatga taaaaatatc tgaactgatt aataagtata aaaccatgga taaaataatt
    74881 tttattgttt cccatgatat agaattttta aatgaagtgg cagatgaaat ttttgaattg
    74941 taaaatagag tctgttaaac atgtctatag aactagtaaa ttgtctaaaa atttaaaaga
    75001 tactaacaca tattgatatt tattagaaaa taaacttcag gatttttaca gtatttataa
    75061 actttataat atgtatttat agtattaata atttccatat ctttagggaa attctttatt
    75121 tacttaccat aattaaagag atgagagata aatatcggca gtcttcggac tgcctttatt
    75181 tttttactta atttaatgca gtaaatcata cgattgaaag gaatctgcgt tatatgctat
    75241 aattaggtgg ttaatctata catttagaaa ggtaaaatat agaattggag aatgatatgg
    75301 gattttcata taataaattg taaccgtcca ataacgaagt atattgaaaa atctccagac
    75361 tag
//
LOCUS       DAVBOH010000002        69961 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOH010000002 DAVBOH010000000
VERSION     DAVBOH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.002"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            624..1265
                     /locus_tag="VQ873_000078"
     CDS             624..1265
                     /locus_tag="VQ873_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3106426.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            1278..1448
                     /locus_tag="VQ873_000079"
     CDS             1278..1448
                     /locus_tag="VQ873_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106427.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ873_000080"
     CDS             complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ873_000080"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3106428.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3822..4278
                     /locus_tag="VQ873_000081"
                     /pseudo
     CDS             3822..4278
                     /locus_tag="VQ873_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4281..5293
                     /locus_tag="VQ873_000082"
                     /pseudo
     CDS             4281..5293
                     /locus_tag="VQ873_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            5268..5846
                     /locus_tag="VQ873_000083"
     CDS             5268..5846
                     /locus_tag="VQ873_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3106429.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5903..6187)
                     /locus_tag="VQ873_000084"
     CDS             complement(5903..6187)
                     /locus_tag="VQ873_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3106430.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(6241..7176)
                     /locus_tag="VQ873_000085"
     CDS             complement(6241..7176)
                     /locus_tag="VQ873_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3106431.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            7280..7723
                     /locus_tag="VQ873_000086"
     CDS             7280..7723
                     /locus_tag="VQ873_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3106432.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            7839..8105
                     /locus_tag="VQ873_000087"
     CDS             7839..8105
                     /locus_tag="VQ873_000087"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3106433.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            8102..8476
                     /gene="crcB"
                     /locus_tag="VQ873_000088"
     CDS             8102..8476
                     /gene="crcB"
                     /locus_tag="VQ873_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3106434.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            8470..8799
                     /gene="crcB"
                     /locus_tag="VQ873_000089"
     CDS             8470..8799
                     /gene="crcB"
                     /locus_tag="VQ873_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3106435.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            8918..9265
                     /gene="rplS"
                     /locus_tag="VQ873_000090"
     CDS             8918..9265
                     /gene="rplS"
                     /locus_tag="VQ873_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3106436.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9307..9378
                     /locus_tag="VQ873_000091"
     tRNA            9307..9378
                     /locus_tag="VQ873_000091"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9340..9342,aa:Arg,seq:cct)
     gene            complement(9544..10542)
                     /locus_tag="VQ873_000092"
     CDS             complement(9544..10542)
                     /locus_tag="VQ873_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3106437.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ873_000093"
     CDS             complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ873_000093"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3106438.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(11404..12708)
                     /locus_tag="VQ873_000094"
     CDS             complement(11404..12708)
                     /locus_tag="VQ873_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3106439.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            12780..13157
                     /locus_tag="VQ873_000095"
     CDS             12780..13157
                     /locus_tag="VQ873_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3106440.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            13248..13580
                     /locus_tag="VQ873_000096"
     CDS             13248..13580
                     /locus_tag="VQ873_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3106441.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            13592..15163
                     /gene="ffh"
                     /locus_tag="VQ873_000097"
     CDS             13592..15163
                     /gene="ffh"
                     /locus_tag="VQ873_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3106442.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15358..16641)
                     /locus_tag="VQ873_000098"
     CDS             complement(15358..16641)
                     /locus_tag="VQ873_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3106443.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ873_000099"
     CDS             complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ873_000099"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3106444.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            17702..18262
                     /locus_tag="VQ873_000100"
     CDS             17702..18262
                     /locus_tag="VQ873_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3106445.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            18264..19163
                     /gene="htpX"
                     /locus_tag="VQ873_000101"
     CDS             18264..19163
                     /gene="htpX"
                     /locus_tag="VQ873_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3106446.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19207..20766)
                     /locus_tag="VQ873_000102"
     CDS             complement(19207..20766)
                     /locus_tag="VQ873_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3106447.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            21491..22033
                     /locus_tag="VQ873_000103"
     CDS             21491..22033
                     /locus_tag="VQ873_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3106448.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            22033..22662
                     /gene="nth"
                     /locus_tag="VQ873_000104"
     CDS             22033..22662
                     /gene="nth"
                     /locus_tag="VQ873_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3106449.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ873_000105"
     CDS             22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ873_000105"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3106450.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            23413..24336
                     /locus_tag="VQ873_000106"
     CDS             23413..24336
                     /locus_tag="VQ873_000106"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3106451.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            24386..25465
                     /gene="carA"
                     /locus_tag="VQ873_000107"
     CDS             24386..25465
                     /gene="carA"
                     /locus_tag="VQ873_000107"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3106452.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEKARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            25778..28954
                     /gene="carB"
                     /locus_tag="VQ873_000108"
     CDS             25778..28954
                     /gene="carB"
                     /locus_tag="VQ873_000108"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3106453.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(29229..30038)
                     /locus_tag="VQ873_000109"
     CDS             complement(29229..30038)
                     /locus_tag="VQ873_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3106454.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(30040..30843)
                     /locus_tag="VQ873_000110"
     CDS             complement(30040..30843)
                     /locus_tag="VQ873_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3106455.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ873_000111"
     CDS             complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ873_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3106456.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            32676..33383
                     /locus_tag="VQ873_000112"
     CDS             32676..33383
                     /locus_tag="VQ873_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3106457.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            33388..34410
                     /locus_tag="VQ873_000113"
     CDS             33388..34410
                     /locus_tag="VQ873_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3106458.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            34427..35296
                     /gene="licA"
                     /locus_tag="VQ873_000114"
     CDS             34427..35296
                     /gene="licA"
                     /locus_tag="VQ873_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3106459.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLVKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLVEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            35286..36164
                     /locus_tag="VQ873_000115"
     CDS             35286..36164
                     /locus_tag="VQ873_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3106460.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            36176..36865
                     /locus_tag="VQ873_000116"
     CDS             36176..36865
                     /locus_tag="VQ873_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3106461.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            36963..37811
                     /gene="dprA"
                     /locus_tag="VQ873_000117"
     CDS             36963..37811
                     /gene="dprA"
                     /locus_tag="VQ873_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3106462.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            38695..39738
                     /locus_tag="VQ873_000118"
     CDS             38695..39738
                     /locus_tag="VQ873_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3106463.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            39905..41992
                     /gene="topA"
                     /locus_tag="VQ873_000119"
     CDS             39905..41992
                     /gene="topA"
                     /locus_tag="VQ873_000119"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3106464.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            42098..42457
                     /locus_tag="VQ873_000120"
     CDS             42098..42457
                     /locus_tag="VQ873_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3106465.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            42550..43182
                     /locus_tag="VQ873_000121"
     CDS             42550..43182
                     /locus_tag="VQ873_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3106466.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            43226..43882
                     /locus_tag="VQ873_000122"
     CDS             43226..43882
                     /locus_tag="VQ873_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3106467.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            43901..44533
                     /locus_tag="VQ873_000123"
     CDS             43901..44533
                     /locus_tag="VQ873_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3106468.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            44561..44995
                     /locus_tag="VQ873_000124"
     CDS             44561..44995
                     /locus_tag="VQ873_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET3106469.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            45007..46044
                     /gene="leuB"
                     /locus_tag="VQ873_000125"
     CDS             45007..46044
                     /gene="leuB"
                     /locus_tag="VQ873_000125"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3106470.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            46041..46310
                     /locus_tag="VQ873_000126"
     CDS             46041..46310
                     /locus_tag="VQ873_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3106471.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            46314..46673
                     /gene="leuD"
                     /locus_tag="VQ873_000127"
     CDS             46314..46673
                     /gene="leuD"
                     /locus_tag="VQ873_000127"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3106472.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIVAYEKQRPAYWQD"
     gene            46835..47459
                     /locus_tag="VQ873_000128"
                     /pseudo
     CDS             46835..47459
                     /locus_tag="VQ873_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            47622..49535
                     /locus_tag="VQ873_000129"
     CDS             47622..49535
                     /locus_tag="VQ873_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3106473.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            49522..50838
                     /locus_tag="VQ873_000130"
     CDS             49522..50838
                     /locus_tag="VQ873_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3106474.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKLKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            51013..51999
                     /locus_tag="VQ873_000131"
     CDS             51013..51999
                     /locus_tag="VQ873_000131"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3106475.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            52063..52134
                     /locus_tag="VQ873_000132"
     tRNA            52063..52134
                     /locus_tag="VQ873_000132"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52096..52098,aa:Arg,seq:ccg)
     gene            52317..53015
                     /locus_tag="VQ873_000133"
     CDS             52317..53015
                     /locus_tag="VQ873_000133"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3106476.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            53006..56545
                     /gene="smc"
                     /locus_tag="VQ873_000134"
     CDS             53006..56545
                     /gene="smc"
                     /locus_tag="VQ873_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3106477.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPQGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            56542..57336
                     /locus_tag="VQ873_000135"
     CDS             56542..57336
                     /locus_tag="VQ873_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3106478.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            57336..58154
                     /locus_tag="VQ873_000136"
     CDS             57336..58154
                     /locus_tag="VQ873_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3106479.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ873_000137"
     CDS             58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ873_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3106480.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(59491..60978)
                     /locus_tag="VQ873_000138"
     CDS             complement(59491..60978)
                     /locus_tag="VQ873_000138"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3106481.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     VELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(61127..61867)
                     /locus_tag="VQ873_000139"
     CDS             complement(61127..61867)
                     /locus_tag="VQ873_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3106482.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(61867..64032)
                     /locus_tag="VQ873_000140"
     CDS             complement(61867..64032)
                     /locus_tag="VQ873_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3106483.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            64205..65158
                     /locus_tag="VQ873_000141"
     CDS             64205..65158
                     /locus_tag="VQ873_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3106484.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ873_000142"
     CDS             65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ873_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3106485.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            67233..67796
                     /locus_tag="VQ873_000143"
     CDS             67233..67796
                     /locus_tag="VQ873_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106486.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            67762..68250
                     /locus_tag="VQ873_000144"
     CDS             67762..68250
                     /locus_tag="VQ873_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106487.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            68324..68791
                     /locus_tag="VQ873_000145"
     CDS             68324..68791
                     /locus_tag="VQ873_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3106488.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(68788..69303)
                     /locus_tag="VQ873_000146"
     CDS             complement(68788..69303)
                     /locus_tag="VQ873_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3106489.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(69315..69842)
                     /locus_tag="VQ873_000147"
     CDS             complement(69315..69842)
                     /locus_tag="VQ873_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3106490.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        21393 a        12501 c        15211 g        20856 t
ORIGIN      
        1 aaaagcgtcg ttaatgatgc attaaagaac agtcgagatg aaaaaatcat gtgacgcacc
       61 aagggaggag tctgcccttt tgaggaaatc tagcgaggaa aaacgatact ggaacagcag
      121 aaagtaaaac tgacctcatg aggaggaaga aagtggctca tgaggtcagg ggttttgtaa
      181 gttacatcta gttgagagag gtatgaatga tttgggttta atcagatggt ttacctcctt
      241 ttcatcggta ttcaccactt tttcaatagt aaagacgaga tggtcttgcg gcaagaaaga
      301 actgatttct agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc
      361 cttctaaatg gtttattggg caattctatt ttaccaagac tatcgcaacc atgcaaaaaa
      421 gcaacggcaa atccgcttct tttttggaga taagagacta ttgtcccaga ctcttagtac
      481 tggttggagg atacgatgaa agatagttat tggttaaatt attttccgga gtatagttta
      541 gaaacgtttg aagtagaata gatattaagg acctatcttt ctcttattcc aaagactcag
      601 ctcttgtaat agaaaattta aatttgacta ttgagtcagg acagagaatt gcactagtcg
      661 gtcaaccggg gtcaggaaaa agtacattat caaaaatacc atcaggatta tataagattg
      721 atacaggaaa agttttattt gatggtgtaa atattaatca aatagataaa aaaatattaa
      781 gtcaaaattt aggagtagtt ccacaggatt cgtttttatt gaacagaagt attcttgata
      841 acataacttt aaagcacgaa gttacttcac aaaagataga ggaagtttgt aaagcagttc
      901 aaatctatga tgaaatcatg gctatgccga tgaaatttaa tactatcatc tcagagatgg
      961 gttcaaatat ttcaggtggt caaagacaac ggatagcact ggcacgtgca ttaataaata
     1021 atcctagtat tgtaatttta gatgaagcaa ctagtgcttt agacactatt aatgaggaaa
     1081 gaataacaaa gtatataaaa agtcagggct gtactcaaat aattgtagct catagattgt
     1141 caacgattaa ggatgcggat attattgttg taatgaaagg tggtaagatt gttgagtcag
     1201 gaaatcataa gtacttaatg gatcttggtg gagagtacta cagcttatat acaaaaagga
     1261 aatgaggtgt aaagaaaatg aagaaagaaa atgaatatgt aattttaaca acagcctcac
     1321 taggggtgat gattggaata gtgtttgcaa tttttttaga ttttccagtt gaatatggta
     1381 tttctttagg attgttgaat ggaatagtat tgggttcgct gattgtttac aaaaacaata
     1441 agaattaagc ataatttttt gctgtaaact aaggagtaga gatggctata gttgaaatta
     1501 taaatctaac aaaaagcttt aaagatattg aagttattca taacacttaa ataatagagc
     1561 aactacagta gtagcttaaa aacatgatta aatcgctatt cttaggagta gcgttttttc
     1621 tttttgttta atactctttg aaaatctctt caaaccacgt cagctttgcc ttgccgtact
     1681 caagtacagc ctgcgactcg cttcctagtt tgctctttga ttttcattga gtataaaaag
     1741 ggttaagtaa gtatagtaaa ttgaaataag atatgaacaa atcgattaga aaagtcaaat
     1801 taatttctag aaatatgtta gaaattggtt tgaattccgc aatcaatttg ttcagttttt
     1861 atttcattta attagaattt cccaactgtc taactcaact aaaaatcccc aatcgtagtg
     1921 attgaggatt aagcaaataa atcttaaaca ataccttggg caatcatagc gtttgctaca
     1981 ttttcaaagg cagcaatgtt agctcctgca aggtagtctt tatcaagacc gtatgtttct
     2041 gaagtcgttt tagctgtgtt gaagatgttt gtcatgatgt ctttgagacg gtcatcaact
     2101 tcttcacgag tccatgagag gcgaagactg ttttggctca tttcaagagc tgaaacggct
     2161 acaccaccag cgttggcagc ttttgcaggt ccgtataaga taccattttc tttgtaaact
     2221 ttgatggcat caaggtcgct cggcatgttg gcaccttcag atacacagat aatgccttga
     2281 gcaaccaaac gtttagctgc ttcaccgttg atttcgtttt gagtggcaca tggaagagca
     2341 atgtcatagt ttccagcgta agtccataca gtaccttcgt ggtaggttgc agttgctttt
     2401 tcagctgcat actcagtcaa acgagcacga cgtttttctt taacatcaac caaaagatcg
     2461 aagtcgatac cattttcatc gatgacataa ccatttgagt cagaaacaga aataacagtt
     2521 gcaccgagtt cagttgcttt ttgaagagca tattgagcaa cgttaccaga acctgaaata
     2581 acgactttct taccagcaaa gctgttaccg ttagctttga gcatttcttc agtatagtaa
     2641 accaaaccgt aaccagttgc ttctggacga atcaagctac caccaaatcc aagaggttta
     2701 ccagtcaaga caccagcatc aaattggtta agacgtttgt attgaccgta aaggtaacca
     2761 atttcacgtc caccaacacc gatatcacca gcaggtacgt caagtgatgg tccgatgtgt
     2821 ttttgcaatt cagtcatgaa gctttggcag aagcgcatca cttcagcatc tgttttacct
     2881 ttaggatcga agtctgatcc acctttacct ccaccgatag gaagtccagt caagacattt
     2941 ttaaagattt gttcaaatcc gaggaatttc aagatccctt ggtttacagt tgggtggaaa
     3001 cgaagtccac ctttgtatgg tccaacagct gagttgaatt gaacacggta accacggttt
     3061 acttgaattt ttccatcacg gtcaacccaa ggaacacgga aagaaaccac gcgctcaggc
     3121 tcagtaatac gtgccaagat attttcttcg atatactcag ggtgtttttc aaatacaggt
     3181 tctaaagtgt tgaaaaattc ttcaacagct tggaggaatt cagcctcgtg cccgttacga
     3241 gctttcacag tttcaaacac gctttggata tattctttag cagatgtcat atcgttctcc
     3301 ttttattgtc atattttatt acataagaca ttatagcaga attttttttc actgtaaaga
     3361 aaaaacagaa attttctaaa aattctttca attcagtttt ttggtttttt tgaaaataga
     3421 taaaaaaacg aacgtttttc ttggaaatat ctttctcaaa gacaaaatct taaagtatgc
     3481 tataagaaaa gaaaatgttt agcaattcag aaatcacttg ttaatttatc cgtgatatgt
     3541 tagatttgcc agtaaaacta tgaccatttt ggagaaaagc aatatttaga ctagactaaa
     3601 ataaaaaagt attatataat agtgatatga aatcaactaa agaagaaatc caaaccatca
     3661 aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat
     3721 agtaaaacga aacaagaaca gggcaaatcg atcaggacag tcaaatcgat ttctaacaat
     3781 gttttagaag tagaggtgta ctattctagt ttcaatctac tatatttcgt ctgatgggca
     3841 aatcttataa agagattata gagcttttag actgtaatca aacaacgatt tggcgaaatg
     3901 taaaaaaata tgaggagttc ggactcgact ctctctttca agaaacacgt ggtggtcgta
     3961 accatgcata tatgacggtt gagcaagaga aagcctttct tgctcgccat ttgaaggctg
     4021 cagaggcagg agaatttgtt acaattgatg ccttatatca ggcttataaa aaggagttag
     4081 gtcgttccta cacacgtgat gccttctatc aactgttgaa gcaccatggt tggcgaaata
     4141 ttatgccacg tccagaacat cctaggaaag cagacgctca aaccattgtc gcgtctaaaa
     4201 ataaaatctt aattcaagaa gacaagaaag cgctttaaat atagtagacg ttttcgtaag
     4261 gttcgcttga tgtaccaaat agtacgccca tgcaaaagaa tatctatttt gttgtcttgg
     4321 acctgcatac gacggataga gataaaatta tccagctatt caaggattgg acggattata
     4381 gtgccaagtt ggtcgagggg gaattggtta aaaaagatgg acagaatgct ctctttcctc
     4441 cgagcgatac tggtgagaca gttgggctca atcctcatcg tttgacgctg acttttggtg
     4501 tatctgcaag tttcttgaaa aagatgaact tggaaaacaa gcgccctcga ctgttcaggg
     4561 atttacctct atttcctaag gagcaattac gtgaaaaata tactggtgga gatattgtga
     4621 ttcatgcttg tgcagatgat gagcaaattg cctttcacgc tattcgcaat ctcatacgta
     4681 aggggagaaa tgcggtgccc cttcgttgga gtcagtctgg atttgcagct atcggggacc
     4741 gaatggagac tccgcggaac ctctttggtt ttaaggatgg aacagcaaat ccaaccaagg
     4801 agcaagactt tgaccgcgtt atctgggctg atagtaagga ctggatggaa aatggttctt
     4861 atatggcagt tcgtcggatt cagatgtttt tagagacctg ggaccgcact ggtctctaag
     4921 aacaagaaaa tacctttggt cgttacaagg aaagtagtgc ccctttcggt aaaaaaatga
     4981 gtttgatgaa gtgaatttga gttttttgct agatgattcg catgttcgtt tggctaagta
     5041 agtggacaag ccacttttgc gttgttctta ctcttactca gatggcattg atgaaaagac
     5101 tggtcagttt gatacgggtt tgctcttcat ttctttccag aaggatcctg ataactttgt
     5161 taaggttcaa actaatctag gtgctactga taagatgaat gaatacatca ctcacatagg
     5221 tagtggactt tttacttgct ttggtggtgt ggagaaagga gactacattg gtcagaaatt
     5281 attggaaagc taggagctgg ttgcttgttt tagctttgtc atttttaatt ctttccccag
     5341 taggtgccca agaaagtttg agttcttatt tcgtaaaaat cacagatact tctaaagcgg
     5401 tcaaaaatgg caatcagtct gaggcccaga aacttgttca agagatggca tcagacttcg
     5461 aaagagtaga aaataaggat tctgaggttg gtaagattgt taaggaaaag ttagctctat
     5521 ctggagatat tactgaagcc aaactcaccg aaatttcctc agctctatta gcttttgaaa
     5581 aagaacaaaa tcctgttgac ctagatgcgg aaaaggaaaa attggtaaac cgtctaagtc
     5641 ctcgttttga aaccttagag caggccattg cctccaaaga tttggaaaaa gtccgagaag
     5701 cttttaagaa aatgaattcc acttggacca tcaatgaaag tgtggttcgt gacaatagta
     5761 tagctcatta tggacgtgtt gaaacagcta tttccttcct gcctagtagc atggaaaccg
     5821 aacctacaga tgagtctgga acatgaaaac agcagttgat ttcaagaaac aaaaaggaac
     5881 agccgaaact gttctcttat cattatttga gaccgtattt tttgttgaaa cgatccacgc
     5941 gtccatctgc ttgagtgaac ttttgacgtc cagtgtagaa tgggtgtgag tctgatgaaa
     6001 tttccacacg gatcaatggg taagtctcgc cttcgaactc aactgtttcg ttagagcgtt
     6061 ttgttgaacc gctaaggaat tggtaaccag tagttgtgtc catgaagaca actgggcgat
     6121 attctggatg gatatctttt ttcattttgc aatatttcct ttctgccatg gtctctttgc
     6181 gagccataga ttgttaccat actagtctat cagattctga aaagtttggc aagtatttta
     6241 tcagttttta agcaagtttt ttaacttttg gtagatgatt tcgttttcct ctaggctata
     6301 ggaattagca ccacttgcta gagggtggcc tccaccatca tgttccttgg caatttcatt
     6361 gataggatgg attttactgc gtaagcgaac gcggtagtgg ccatcagcct gttccacaaa
     6421 aattccccag agactaacac tatcaatacg cccaggtgca cttacaatgg ctgcagtttc
     6481 agcatcggtt acattgtatt gtttcaagac ttcttgactc aggataacgc gagcagcacc
     6541 attttcatcc acttccagat ggtcgtagat gtagccttgc agtttagcaa ttttgtagct
     6601 catagtgtcc attttgcgag tgagagccgc aaagtcaaag ttatgttctc tcaaataagc
     6661 agccaggcga agagtccgtg cagtggtaga agggtagagg aagcgacctg tatcaccgac
     6721 aattcctgca aagagcaact cagcatcgcg atctgccaag gctagttggg ttgtttgggc
     6781 aaatagggta atcatctcgc tagcgctact tgaactagta tcgacccaag acaggtcacc
     6841 gtatacatca tcatttggat ggtggtcaat cttaatgaga aaatcacctt gactatagcg
     6901 tttatcatcg atacgagcag tattagctgt atcacagacg atgacaagtg cgccttggta
     6961 ggccctatct tcaacaagat ccatctcagc catccaagta agagttggtt catcaaaacc
     7021 gacggctttg atggtttttt ctgggaaatg atgttccagc aaggctttca atcccacctg
     7081 acttcccaag gcatcagggt ctggtttcat atgacgatga atgataatgg tgtcgtattc
     7141 tttaattttt tctaaaattt gttggcaaat ctccataaat aacctcaatt ctttctcatt
     7201 tcattgtagc acaagaattt ttatttttaa aatgaaaaag atgtgatata atggagaaag
     7261 ataaattgag gaggacgata tggcattagc aaaaattgta tttgccagta tgaccggtaa
     7321 taccgaagaa attgcagata ttgtagcaga caaattacgt gacttgggct tggatgttga
     7381 tgttgatgaa tgtacaactg ttgacgcttc agacttcttg gaagcagaca tcgctatcgt
     7441 tgcgacctat acttatggtg atggtgaatt gccagatgag atgatggact tctacgaaga
     7501 cctagcagat ctcaacttga atggcaaaat ctacggagtg gtcggctcag gagatacctt
     7561 ctacgatgaa ttctgtaagg ctgttgatga ctttgaccgt gtctttgtgt caacaggagc
     7621 agaaaaaggt tcagagtgtg ttaaagttga tctttctgcc gaggaagaag atattgaacg
     7681 cttggaacaa ttcgcagaag aattggttgc taaagtagga taagcataaa agtgcgctga
     7741 tgtaatcaat cagtgcattt ttcttatcga gagttgggat tttactagcc taattgatgg
     7801 ctttttgata caataattca aataaaggag gagactgtat ggatttagat attattcgtc
     7861 aagaaatcga tcaaatcgac gaccaaattg tcaaactgtt agaagaacga atgcatttag
     7921 ttgagggggt ggttgcttat aagaaagctt caggtaaacc gattttagat actaagagag
     7981 aagaagttat ttttgaaaag gttgggagtc gtgtagagga caagcgctat caggagacta
     8041 ttgtagcgac tttttcggac atactcaaac gttcgcgtga ttatcaggat caaaatatca
     8101 aatgaaaaaa gaacaatttt atccgctagg aatttttcta gctgctatgt tgggcggact
     8161 tgtccgatat ctagtttcca cctggttacc agccagtcca gactttcctt ggggcactct
     8221 ctttgtcaac tatctgggaa ttttctgctt gatttatctt gtcaagggct atctggtcta
     8281 taaggggact agtaagggct tgattttagc actggggacg ggtttttgcg gaggtttaac
     8341 aactttttcc agcctaatgc ttgatactgt gaagctgctt gatacagggc gttatcttag
     8401 tttgatactg tatttgcttt tgagtatcgg tggaggcctg cttttagctt actatttggg
     8461 gaggaagaaa tggtaatcgt ctatcttgca atcgcctgtg gcttgggagc actcgtacgg
     8521 tatttctttt ctcgctataa tcaagtttct aaattgccac tcggaacgct catagctaat
     8581 cttttaggtt gttttttaat tggagtattc tacaatcatg tagagtctaa ggaagtatat
     8641 gctattctag caacaggatt ttgtggcggt ttaacaactt tttcgacctt gaatgacgaa
     8701 cttcaaagac tgctaagtga taagaaggtc ttttattctt acctgacttt gacttacata
     8761 ggtggtttgg ttgcgatttt tttaggaatt ttgctataaa tttctttact tttttttaga
     8821 aatttggtaa actgtatctt gtgtgtaatg gacgcacaaa aatacagttt atccgctgag
     8881 gaagattcct caagattgac aaagatagga gaataaaatg aatccattaa tccaaagctt
     8941 gactgaaggt caacttcgta cagatatccc atcattccgt cctggtgata ctgttcgtgt
     9001 acacgcgaaa gttgtcgaag gtaaccgcga acgtatccag atttttgaag gtgttgttat
     9061 cgcacgtaaa ggtgctggaa tctcagaaaa ctacacagtt cgtaaaatct ctaacggtgt
     9121 aggtgttgag cgtatcttcc caatccacac tccacgtgtt gaaaaaatcg aagttgttcg
     9181 ttacggtaaa gtacgtcgtg cgaaattgta ctacttgcgt gctcttcaag gtaaagcagc
     9241 tcgtatcaaa gaaatccgtc gttaattcga ctaaaaaact ctgcttttca gcagagtttt
     9301 tatctagctc ccttagttca atggatataa caactccctc ctaaggagta gttgcaggtt
     9361 cgattcctgc agggggcagt aattagatat caaagaagtt tgtcaaaaag tctttgatat
     9421 taaaagaacg cataatatag gggattgtct ccataatatt atgcgtttta ttattgaaaa
     9481 atttgggcaa tcatcagata aaattgagac tatatcgagt atataaatgt ttgtatagtc
     9541 aatttattca aaatcgtcaa gttctaaatt atttaaagga ctataacatt catatttctt
     9601 taagtaattg tttatttctt cagcagtgga acgaggtaaa ttaactctta aatagtcaat
     9661 atcttcctta gataaaaaat gatttgcatt caaaattgag aagcgaaata atgcttcatc
     9721 aaaagcaaaa tcataatcgt catcagataa tgattccatt aatgtttgaa tatgttttag
     9781 tgagtagtca ggtatcgaat cgggataata tactggataa tcagtggctg aaaaattgtt
     9841 ttctaatcct gaaatagtaa ttatcaaaga ttctatgtaa tatattaaag catgtttaat
     9901 attaccttct tgttccaaat gtcttccctg agcctttcgt gtgttagata agcatccaaa
     9961 atctcctgat acagtattcc tatgagcttg tttatttaag agactccatt ttatatcacc
    10021 aaaagttgct ttaaaagaga tattgttttt ttctttacaa taatcttcca tacttatgtc
    10081 tttatcatag tatgctttga tatagtcact atgttcgata ataagatttt gtgcttcttt
    10141 tgttagttta aattcgaacg gaatatctaa tttgtcaacg ttgatattat taattattct
    10201 tgtaattaat tctgcttttt ttccagaagt agctaaatta tgtttagata atatagtttt
    10261 taattctact actttaagat atgataaagt cttattttta gtgaagtatc ctaatttgta
    10321 taattgattg tgtgtagatt cagggtcaat ttgaagagag tatttaaaat atcttgggaa
    10381 attataattt ctccctgttt tttgagtcca atctatgagt atgagttgcc caggagtaag
    10441 gccgcactct aatttgttta ggtaaaaatt gttacaatca gaatttgtgt ctctattatg
    10501 attattttgt tttaaattaa atagtttgct aaaaaaattc attggatttt attgctaatc
    10561 aattcttatt gaaaaatgat acttttacag tacccatgta cggatggcat gggcaacgcc
    10621 agattcatca ttagatttag tgatgtattt ggcgattttt ttgatttctg gatttccatt
    10681 ttccatgaca acagggttgc caacgacttc cagcatggca cggtcatttt cttcgtctcc
    10741 gatagccatg gtttcatctt tggttaatcc tagtttttca gctaagtgag taatagctga
    10801 acccttgtct acattctttt taaggagttc gaggtagaaa ggagcagatt tgttgataga
    10861 gtagtgctcg taaaattcgg ctggtatttt ttcaatcgca gcatcgagaa tttctggttc
    10921 atcgataaac atacatttaa caatttcttt gccagccatt tcttcagggg tacggtagaa
    10981 gataggcatg ctgacgaggg ttgattcgtg tacagtgtat gttccgatat tgcgatttgc
    11041 agtatagata ccgtccttgg taatggcatg catgtggaca ccgagcttgc gactgaggaa
    11101 ttccatatcc agataatcct cataggtcaa ggattcgctg ataatctcat ggccagtagc
    11161 agtttcttgg acaagggcac cattgaaggt caccacatag tcaccttggt ctctcaactg
    11221 caagtcgtct agaagtttgg caacacctgc gatggggcgg ccagttgcaa tcacgacttt
    11281 gacaccagct tctttggcat cttggatggc agaaaagact tcaggagtga tttccttttg
    11341 gctgttgaca agggttccgt cgatatcaac ggcaattagt ttaatactca taaatttcct
    11401 cttctagttt ttatttgggg taaaatgatc gttctcaatc aagtataaaa attgctgggt
    11461 aatgctagca aagatactgt tttgatctaa catttctttc ggaaaataga aacgattatc
    11521 tccgtgacga ctaccagcaa gggattggac gataggagac aggctagaga gttcggccag
    11581 ttctccattc ttttgtaaaa tctcaatctg tgtccgtgga ttttcagatt cgggacgata
    11641 gatatcataa gggaggtcaa agttcttatg aatggcagta tagtagtcgg gatcaaagcc
    11701 aatgtcctca accaattttc tcatgctagc gagttggtct tgatcttctt gtgaaaaggt
    11761 aatggattta aagaccttgc ggttgacaaa gcgttgcgat aaatctgcga gaattttgtc
    11821 aggactggtc atccagagct ggaagtaggt attcatcaca ccatcatcta gagccagata
    11881 gtcagacaag gtcacatttt tttcaaagaa aggcaggagg tgtggggaag ttcgtgcaaa
    11941 gaagtctttg tccttagggt agagttcctt agcgcgcttg agaagattct gtaggagaac
    12001 ttccatagcg cgtgttgctg ggtggaaata gacctgcata tacatctggt agcgactgag
    12061 gacatagtct tcgatggcgt gcatgccatt gcgctgaaag gcgataccat tttcgatagg
    12121 acgaatgact cggaggattc gagtcaggtc aaattcccca taggatgctc ctgtaaaata
    12181 ggagtcacgc aagagatagt ccatgcgatc tgcgtcaatc tgactagaaa tgagttgtac
    12241 gacctgcttg ttaggatagg tatggtctat gacactggca actttctctg gaaaatcggg
    12301 cgctacttgt agcaagactt ggtgaatctc tgtctcagga ctttgaataa tctcctgagt
    12361 aatagcttca tggtctgtat caaagagatg ttcaaaagta tgggagtagg cgccatgccc
    12421 aaggtcatgt aggagagcag cgatcatggt caagagagac tcggcaggat tccattcctc
    12481 aggatatttt tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga ctcctagaca
    12541 gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc ccagttgttt
    12601 gatccggcgc aaacgctgaa attcttttgt attaatcaag tcatagatga tttgattaat
    12661 gacatggatg tagttgtgaa ctgggtcacg gaatactttt tcgttcatat gaccattata
    12721 gcaaaatcct gctctttttg gtaaaatagt aggacaagag acaagaaaga gggcctgatg
    12781 tgaagattcg gatgcgaaat acaattcagt ttgatgagca gttggaagtg attgaccagc
    12841 tttatgatgt ggaagtgcat gaaaaaggag attatagcta cctgcttttc tataatgagg
    12901 aaaaggaaaa agtagtgatt aaatttcatg gtcaagaact tgtgatgagc cgattttcta
    12961 atcccaagac cattatgcgc tttctaaaga atagcgatag tttagcctat attcctacac
    13021 ctatgggcat gcaggagttt atcatccaaa cgagccatta tcaagttgat aggcaaaaga
    13081 ttgaactaga ttatcaacta caaaatcaag agggacatcc ttttgccagc tatcaattgg
    13141 aaattacttg gggctaggct catgtctttt tcaaatttag ctatctatct tcttggatcg
    13201 gtttcctagt gtggtagatt aggctaattt ttggtataat aaaagttatg gaaatcgaaa
    13261 aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc gcttttgaca gataagcaaa
    13321 tgaattatat cgagctctac tacgctgatg attacagcct tgctgaaatt gccgaggagt
    13381 tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg aacagaaaag attctggaag
    13441 attatgagat gaaattgcac atgtactcgg actatattgt ccgcagtcag atttttgatc
    13501 agattttgga gcgctatccc aaggataact ttctgcagga gcagatagaa attttaacaa
    13561 gcattgataa tagagaataa gaggaagaaa aatggcattt gaaagtttaa cagaacgttt
    13621 gcagaacgtc tttaaaaatc tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga
    13681 ggcaaccaaa gaaattcgct tggccttgct cgaggccgac gttgccttgc ctgttgtaaa
    13741 ggactttatc aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg atacacttaa
    13801 tcctgcgcaa cagattatta aaatcgttga tgaggaactg acagccgttt taggttctga
    13861 tacggcagaa attatcaagt cacctaagat tccaaccatc atcatgatgg ttggtttaca
    13921 aggggctggt aaaacaacct ttgctggtaa attggccaac aaactcaaga aagaagaaaa
    13981 tgctcgtcct ttgatgattg cggcggatat ttatcgtcca gctgccattg accagcttaa
    14041 gaccttggga caacagattg atgtgcctgt ctttgcactt ggaacagaag taccagctgt
    14101 tgagattgta cgtcaaggtt tggagcaagc ccaaactaat cataacgact atgtcttgat
    14161 tgatactgcg ggtcgtttgc agattgatga gctcctcatg aatgagcttc gtgatgtgaa
    14221 agcattggct caaccaaatg aaatcttgct tgtcgttgat gctatgattg gtcaggaagc
    14281 agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg actggggtca tccttaccaa
    14341 gattgatggc gatactcgtg gtggtgctgc tctgtctgtt cgtcacatta ctggaaaacc
    14401 aatcaagttc actggtacag gtgaaaagat tacggacatt gaaaccttcc acccagaccg
    14461 catgtctagc cgtatccttg gtatggggga tatgctcact ttgattgaga aagcttctca
    14521 ggaatacgat gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa acacctttga
    14581 ttttaatgat ttcatcgatc aattagatca ggtgcaaaat atggggccga tggaagactt
    14641 gctcaagatg attccaggta tggccaacaa tccagccctt caaaacatga aggtggatga
    14701 acgccagatt gctcgtaaac gtgccattgt gtcttcgatg acacctgaag agcgtgaaaa
    14761 cccaaatttg ttaaatccaa gccgtcgccg tcgtattgct gctggttctg gaaatacatt
    14821 cgtcgaagtc aataaattca tcaaggactt taaccaggct aaacagctca tgcagggtgt
    14881 tatgtctggg gatatgaata aaatgatgaa gcaaatgggg attaatccaa ataaccttcc
    14941 taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca
    15001 aggcggtatg cctgacttat cagctctcgg aggagcagga atgccagata tgagccagat
    15061 gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt ccatgaaacg
    15121 tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga gattgatgca
    15181 aatctcattt gatgagaaaa taaagtaaaa atttctatga taaaacgtat agtatcaagg
    15241 ttttagaata tctgatatta tacgtttttt gattttaata attttgttaa gacactttta
    15301 ttatggtatg cgaaaaatcc actcagctgt ctgagtggat taggtgtatt tagactctta
    15361 gtctttattt tcgtatggca agatcaagtt caagatgatt cctgtcatgg ctgaaagggc
    15421 agtacctgaa agtgtaactg gaccaagttt aaggatagct cctccaagtc caagaaccaa
    15481 catagcactt gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa
    15541 gactttcaaa ccattgctgg cgataacccc atagagaagg attgacatac caccaagtac
    15601 agcgtttgga atagttgaaa tcaaggcagt gaatttacca aggaagctga gggcaatcgc
    15661 gatgaaggca gcgttacgga taactgagac agaagcgata cgagtcatac cgataacccc
    15721 tgtattttct ccgtaagttg tattggctgg tccaccaagg aaggcagaaa cagaagttgc
    15781 gataccgtca ccaagaagag tacggtgaag acctggttct tttaagaatt gacgaccaca
    15841 gatttgaccc aaaacagtat ggtctccgat atgttcagaa attgttacga tagcgattgg
    15901 caagatagcg atggcttctg gaccaaagta aagattgtac tctttaaagg caccacctgt
    15961 gctaaatggc aagtagaaac caggaatttc gaaccagttg gctttaagaa ctggtgtaaa
    16021 gtcaaccaag ccaagagtta gtgcgaaaag gtaaccaccg ataatggcaa agaggaatgg
    16081 aatgattcgt aggaagcctt ttccttttgt attgataaag gcagcaatta ggaaagtaac
    16141 aacggctacc agagcatttt tccaatttcc gtctgctaca agacctgcat tggtaacagc
    16201 tgaacctgca agtccaagac cgataacgat gatcatagga ccgataatga ttggtggcaa
    16261 gagtttatca atccattttg ttcctacaaa tcggatgctg gtagcaacaa ggacatagac
    16321 caaaccagtc aagataaccc ctgtttgggc agcagataca tcccccccca tttctttcat
    16381 agccagtgac atagctgtga taaaggcaaa tgaagaacct agataaactg gaactttaaa
    16441 accagtagca atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg caacagatac
    16501 aggcattccc aaaatcaatg gtaccaagat ggtcgcacca aacatggcga aaacgtgttg
    16561 gaagctaagg agaattcctt ttccatccga aggacgttgg tcaacgtcta gtaacaaatc
    16621 aacagttgat tcttgtttca tataaacctc acttttgggc atcagaaaag agcccattat
    16681 tttacagcaa taggccctca gagtaagact tctctaaaat ctagacttta aagagtttca
    16741 aatatttttg cgtcttcgtc acctcacggg atgacattaa aaacctttgc ttaggatagt
    16801 atagcagaaa aaaatgattt tgtaaatcat tttttcccga gcctagaaat aaaagagcga
    16861 ggctgatttt gtaaacattt gtttactaaa aaatttaaag tgggcgttta tttggcatac
    16921 cagccttacg tggatattta tttggtgttt cttttttctt ttctaccact gtgatatagc
    16981 gcggatctct attcggtagg gcgtagctga gattgtcttc gaccttacta aaaaggagat
    17041 tgagggcatt cttagcttct aataattcct caggcgcatt gctggccttg agtgccaata
    17101 gtttgccacc aaccttaagg tagggaatag tcaattcaga taggacctgc atacgggcaa
    17161 ccgcacgagc tgttacaaaa tcatattgag cacggaagtt cttgtcttgg gcaaaatctt
    17221 cggcacgtcc gtggtagaaa tgaactccgt tcaaatccag ttcttgagcc aagagttgta
    17281 ggaagttgat gcgcttattg agtgaatcaa taatggtcac atctaactcc ggatagagaa
    17341 ttttcattgg tagactagga aatcctgccc cagccccgat atcaagaagt ttgatagttt
    17401 cattgggaat caaaccttga agaatgggtg caatcgaatc gtaaaaatgt ttgagataaa
    17461 cttcttcctt gtccgtaatc gccgtcaaat taatcttctc attccactcg accaagagct
    17521 caaaataacg ttcaaattgt tctttttgct ggttcgaaag tggaagattc tgctcggcaa
    17581 gcaagttgta aaatgtttct ggtttcatag ttatttcctt ctttagtatc atcttatttt
    17641 accacaatca tagaaaattt gatatactgg tactaatcta aaagcagaaa ggacttatat
    17701 tatgacttgg attattcttg gagttatcgc tcttattgtt atttttgtga ttgttagcta
    17761 taacggtttg gttaaaaatc gtatgcaaac caaggaggct tggagtcaga ttgatgttca
    17821 gttgaaacgt cgaaatgacc tcttgccgaa cttgattgag actgtaaaag gttatgccaa
    17881 atatgaaggt tctacccttg aaaaggtggc agaactacgt aaccaagtgg cggcagcgac
    17941 ttcaccagca gaagctatga aagccagtga tgccctcact cgtcaggttt caggtatttt
    18001 tgcagttgca gaaagctatc cagatttgaa agctagtgct aactttgtta aattgcaaga
    18061 ggagttgaca aacacagaaa ataaaatttc ttactctcgt caactctata acagtgttgt
    18121 cagcaactac aatgtaaaat tagaaacttt cccgagcaat attatcgctg gaatgtttgg
    18181 atttaaagcg gcagatttcc ttcaaacacc tgaagaggaa aagtcggttc ctaaagttga
    18241 ttttagcggt ttaggtgact aagatgttgt ttgatcaaat tgcaagcaat aaacgaaaaa
    18301 cctggatttt gttgctggta tttttcctac tcttagctct tgttggttat gcggttggtt
    18361 atctctttat aagatctgga cttggtggtt tggttatcgc actgattatc ggctttatct
    18421 acgctttgtc tatgattttt caatcgacag agattgtcat gtccatgaat ggagcgcgtg
    18481 aggtggatga gcaaacggca ccagacctct accatgtagt ggaagatatg gctctggtcg
    18541 ctcagattcc tatgccccgt gttttcatca ttgatgatcc agccttaaat gcctttgcga
    18601 caggttctaa tcctcaaaat gcggctgttg ctgcgacttc aggtctacta gctatcatga
    18661 atcgtgaaga actagaagct gttatgggac atgaagtcag tcatattcgt aattatgata
    18721 tccgtatttc gactattgca gttgcccttg ctagtgctat caccatgctt tctggtatgg
    18781 caggtcgtat gatgtggtgg ggtggagcag gtcgcagacg aagtgatgat gaccgagatg
    18841 gaaatggtct tgaaatcatt atgctagtgg tttccctact agctattgta ctggcacctc
    18901 tcgctgcaac cttggttcag ctcgctattt ctcgtcagag ggaatttctg gcagatgcat
    18961 ctagtgttga gctgactcgc aatccccagg gaatgattaa tgccctagat aagttggaca
    19021 atagcaaacc gatgagtcgc cacgtcgatg atgctagcag tgctctttat atcaatgatc
    19081 ccaagaaagg tggggggttc caaaaactct tttataccca cccacctatc tcagaacgga
    19141 ttgaacgttt aaaacagatg taaaagaatc cagaggtcgt ctctggattt ttgctatgtt
    19201 gcaaatttat aaatcttcta aattaactaa ctccaaaccg tgttctgtca tgcgatagat
    19261 gatcgagcag acttctttta agaaacgacg gtcatgcgaa acagtgatga gaccgcctgg
    19321 ataggttgca aagagttttc tgatttgggg ttgagaagtg ggagaaaagt ttcgtgtggg
    19381 ttcatccagc aggagaaagt ttggtttgcg caggactaga tccaaaagca ggagttttcc
    19441 ctgttgtccg ccagataagg agcgaatttg atgctgcatt tctggataac tgaaattgag
    19501 actggctagg tgagagtgga ttttctgaag ttcctctttt tccccagttt tgctgatata
    19561 agctattggt gataaatcca attgtagttt tttgtggtaa tcttgtggca taaaaccaag
    19621 ggaaatctct cttttatcat tcagaagttg ctttaatttg gctaacagag ttgatttccc
    19681 aacaccattt ggcccgataa taccgatttt ttcttgccca cggacagtta gttgtagttt
    19741 ttgaaccaaa actcggtcgt caatggacaa attttctttt tccagttgga ctaagacttt
    19801 agaagctggt aatggttgga tgtctgaaaa gaaaagttgg atttgttcct cttcaagtgg
    19861 tttttgagtc atggactgag ctgccttttc gtagcgtttt tcttgtgaga ggacagtttt
    19921 catcttttta gccaataggc gaccggcagt actatctttg gtagctcgaa gcgcagtttc
    19981 tacattttgc ttaactctcc gatgtttttc catggtttta tcgtaggctc tttggttgtt
    20041 agcagcttgc tgactttgtt tggcaaaatt agcctttctc tgctcactat agctatcata
    20101 gtctaaatgc tctactagcg tttccgcttc tttacggtgt ttgaccagtc gcaagtgaac
    20161 aatagtgtct gccgtttcag aaagaaagtc ttcatcatgg gaaatgaaaa taacggtttg
    20221 cctggtcttt tgaatctggc cttttagcca atcaactgtc tcaaggtcta ggtcatttga
    20281 aggttcatct aaaaatagaa tctcaaaggg tttggctaac tcatggataa gctgaatttt
    20341 caaagcttct ccccctgata gattgccaat ctcttggtca cttgcgaaac gattgctatc
    20401 aaaatgcaat tcctccgcca aacgatagag gatactgtag tctaaatcaa tagaatctaa
    20461 aaagaagtag tcgtgtaaag ttttcttttt cagctcctcg ggaagttttt gaggaatgta
    20521 ggccagtgac tgatagtcag attggatgtt tcccttgata gtgaaatcag acaaagcttc
    20581 ccccattaaa gttttaagta aggttgattt accatttcct tcttcgccaa taatagctac
    20641 cttttccccg tcttgtatgg tcatgcttag gtcagagaca aggtctcgta aatctttgtt
    20701 ttgtgtgatg gtcaggtgat tgatttttat catactattg ccctttctag aatgttcata
    20761 gtgcataaca aaaagctcta ctttacctag tagagcccaa agtctatgtc aaaaaaactc
    20821 tattaacatg ccagaaaaag ggcataaaag agcacacaaa aagagacaaa aacaagatct
    20881 actaaataaa ggttctttat ttgatagact tagttgttca tgtctccctt acctcctagt
    20941 attagtatct ttatactata cttttaagga aattttgtca acagaaaact ggaaattcta
    21001 tgctctaaaa tccaaaaaca ggtctataga gacttagtac gtgtttgaca tgctcgtaat
    21061 ggattttatc atagtttcgc caagcagtgc gttcttgatt gtttagtttt aggctaccca
    21121 gtccaatcat aggactggtg ggttggtaaa atttctcaag atcaattaag atactgttgt
    21181 tcaacttttc cgttttttga gttcttgcat agtagtgttt agcagctctt gtagtcgaat
    21241 atcatctgcc gtaccctgtt tacagttttg gtagctttta tttaacttgg ataggagttg
    21301 aatgagtttc ttgtcttccg tgtgagcatc ctccttgatc tgatgtactc tttccctata
    21361 gtatagcact aaaaaataaa actgtcatag tgaatatgtt aaaatttcga attttaatta
    21421 caaagtttgg tgtgctgatt tgtagccttt tcatggtata atcaagagag taaatcttta
    21481 tggaggaagt atgaaattaa atattcaaga aattcgtaag cagtctgaag gtttgaactt
    21541 tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa ttttagatgt
    21601 aaaagatatc cttgcagttg ggaaagtaca atatgaagac cgtatgtatt tcttagatta
    21661 tcaactatct tataccattg ttcttgcttc gagtcgcagt atggagccag ttgagttagt
    21721 tgaatcttat ccagtcacgg aagttttcat ggaaggcgca actaaccagc tagatcaaga
    21781 agttttagat gatgacttgg tcttgcccat cgaaaatggg gagcttgacc ttgctgagag
    21841 tgtatcagac aatatcctgc taaacattcc tatcaaggtc ttgacggctg aagaagaagc
    21901 tggtcaagga tttgtctcag gaaatgactg gcaaatcatg acagaggaag aataccaagc
    21961 tcaacaagca gtaaagaaag aagaaaacag tccttttgct ggcttacaag gactatttga
    22021 cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga agaaatcatt
    22081 gccctcttcc cagatgccaa gcctagtctt gattttacca atcattttga actcctggtt
    22141 gcggtcatgt tatcagccca gacgacagat gcagcggtaa ataaggccac accaggtctc
    22201 tttgttgcct ttccaacacc ccaagctatg tctgtagcga cagagagtga gattgcttca
    22261 catatttctc gcttgggatt gtatcggaat aaagctaaat tccttaaaaa atgtgcccaa
    22321 cagttactag acgattttga tggtcaagtc cctcagacac gtgaagaatt ggagagtttg
    22381 gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg taggatttgg gattccagcc
    22441 tttgcagtgg atactcatgt ggagcgtatt tgcaaacacc acgatattgt caaaaaatca
    22501 gcgacgccac ttgaggtgga aaagcgggtc atggatatct tgccgcctga gcagtggtta
    22561 gctgcccatc aggccatgat ttattttgga agagccattt gccatccaaa aaatccagag
    22621 tgtgaccagt acccacaatt atatgatttt agcaatttgt aagatgctac attgaaactt
    22681 tttgcttgat tttaagcatg ctttgtgcta tagtaaatga taactaaata ttcctttaaa
    22741 cctgtcccgt gaggcaggca aggagcgcga taaagtagaa gggtgaagtc tatactgtgt
    22801 gcagtagggc tcgcttggct ataaatttca agtctccttg tttaaggaga cttttctttt
    22861 tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa acgagcgatt
    22921 acgcgtatta cttatgagat tatcgaacgc aacaaagatt tgaataagat tgtcttggct
    22981 ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt gaagcagtta
    23041 gaaaatcttt cagttcctgt tgtggaattg gatactaaac ctttccgtga tgatgttaaa
    23101 agtggagaag atacttcttt ggtttctgtc gatgtgacag accgcgaagt tatcttggtg
    23161 gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta ttgataatat tgtcggtcat
    23221 ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag agaattgcca
    23281 atccgtccag attacgttgg aaaaaatatc ccaaccagtc gttctgaaga aatcatcgta
    23341 gagatgacag aacttgatga ccaagacaga gttctgatta ctgaagaagc ttagaaagtt
    23401 aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc catggaagac
    23461 ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa aaatggagcc
    23521 cagcttccct atgaagacca tccgattgtt tccaatctct tctttgagga ttctacacgg
    23581 acacataagt cctttgaagt cgcagagatt aaacttggat tggaacgact tgactttgat
    23641 gtgaagacta gttcggttaa taagggtgag acactttatg acaccatttt gactctgtct
    23701 gctttaggag tggatgtctg tgtgattcgc catccagagg tcgactacta tagagaattg
    23761 attgctagtc caacgattac gacttccatc atcaatggtg gagatggttc gggccaacac
    23821 cctagccaga gcttgcttga tttgatgacc atttatgagg aatttggcca ctttgagggt
    23881 cttaaagttg ctattgcagg tgacttggac cactcacgcg ttgccaaatc caatatgcag
    23941 attttgaaac gcttgggatc tgaactcttt ttcgctggac ctgaggaatg gagaagtcaa
    24001 gagtttgcag actatggaca gtttgtaacc attgatgaaa tcattgatca ggttgatgtc
    24061 atgatgtttc tccgtgtgca acacgaacgc catgatagtg gagctgtatt ttcaaaagaa
    24121 gactaccatg cccaacatgg cttgactcaa gaacgttacg atcgtttgaa agaaacagca
    24181 atcctcatgc acccagctcc aatcaatcgt gatgtagaaa tagcagacca cttggttgaa
    24241 gcaccaaaat cacggattgt ccaacaaatg accaatggtg tctttgttcg aatggcaatc
    24301 ttagaatccg tactagcgag tagaaacgcc aactaaaaca caagacgtta aaagacgcca
    24361 gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt ctagtattag aagatggcac
    24421 agtttttgaa ggcaaggcct tcggagcaga tattgatgta acaggcgaaa tcgtctttaa
    24481 tacagggatg accggctacc aagaatccat tacagaccag tcttataatg gacaaatctt
    24541 gacctttact tatcctttgg tcggaaacta tggaattaac cgtgatgatt acgaatctat
    24601 tattccaact tgtaagggag ttgttgtttt cgaaaaagcg cgtagagcaa gcaactggcg
    24661 caaccaaatg accttggatg aatttttgaa agccaagaaa attcctggta tttcagggat
    24721 tgatacgcgt gcacttacca agattattcg taagcatggt actatgcgag caaccttgac
    24781 tcatgttgga gatagtatgg accatgtgac tgaccagctc caagcaacag tattgccgac
    24841 agataatatt aagcaggttt ctactaaaac ttcctatcca gctccaggag ttggtttgag
    24901 cgtggtgtta gtagactttg gtctcaagca ctcaatccta cgtgaacttt ctaagcgcaa
    24961 ctgtaatgtg acggttgttc cttattcgac aacggctgaa gaaattctcc atctcaatcc
    25021 tgacggagtg atgttgtcaa acggtccagg taacccagaa gatgttccac aggcactgga
    25081 tatgattcgc ggtgtacaag gaaaaattcc aatctttggt atctgtatgg gacatcaact
    25141 ctttgctatg gcaaacgggg ctaagaccta taagatgaag tttggccacc gtggattcaa
    25201 ccatgcggta cgtgaaatcg caacaggacg agtagacttc accagccaga accatggtta
    25261 tgcagtcagc cgcgaggatt tgccagagca cttgattatt acccacgaag aaatcaatga
    25321 caagtcagtg gaaggtgtgc gccacagata ccaacctgct ttctctgttc aataccaccc
    25381 agatgcagct cctgggccac acgacgctag ctacctattt gacgagttta tcgagatgat
    25441 ggaagttttt aaacaatcaa actaagaacg agtaaaagct cgtcggagaa tttatgtaac
    25501 tgaacacgga cggaaagctc agaatttaga gaaaccaact tggattgtca atccttcctt
    25561 gatttcttaa aattcaatcg ctttctattc gtcctttgta tcttatttaa tgtcgccctg
    25621 agaggcgacg aatagaaagg agaagggtgc tccgtatttg ctgaactgaa tacgggctac
    25681 ggacggtgct aaaaagatag ttattcctag aactgacagt tcttcgtcat aactcctatt
    25741 ttagctttgt ccgcttgacg cccttaatat cttatatatg cctaaacgta ctgatattca
    25801 aaaaattatg gtgattggtt ctggtccgat tattattggt caggctgctg agtttgacta
    25861 tgctgggacc caggcttgct tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa
    25921 ctcaaatcct gcaaccatca tgacggacaa ggaaattgct gacaaggttt acattgaacc
    25981 gattacactt gagtttgtga cacgtattct tcgtaaggaa cgtccagatg ccttgctacc
    26041 aacactcggt ggtcagacag gtctcaacat ggccatggaa ttgtctaaaa atggtatctt
    26101 agatgagctt agcgttgaac ttctgggtac taaattgtct gccattgacc aagcggagga
    26161 ccgtgacctc tttaaacaat tgatggaaga gcttgagcaa cccattccag aatctgaaat
    26221 tgttaacaca gtagaagaag cagttgcctt tgcagcgaca attggctacc cagtcatcgt
    26281 tcgtccagcc tttacccttg gtggtactgg tggtggtatg tgtgccaacg agaaagaatt
    26341 gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg
    26401 ttcgattgct ggtttcaagg aaattgaata cgaagtgatg cgtgactcag ctgacaatgc
    26461 cttggttgtt tgtaacatgg aaaactttga cccagttggg attcacacgg gggattccat
    26521 tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag
    26581 cttgagcatt attcgtgccc tcaagattga aggtggatgt aatgttcagc tagctcttga
    26641 tcctaacagc ttcaagtatt atgttatcga agtaaaccct cgtgtatcac gttcgtcagc
    26701 ccttgcttct aaagcgacag gatatccgat tgctaagttg gctgccaaga ttgcagtagg
    26761 tttgaccttg gatgaggtta taaacccagt tacaggttca acctatgcca tgtttgaacc
    26821 agcccttgac tacgtagttg ctaagattcc acgtttccca tttgacaagt ttgaaaaggg
    26881 tgaacgccgt ctcggtacac aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa
    26941 catcgaggaa tctcttctca aggcctgccg ctcccttgaa attggggtgc accacaatga
    27001 aatacctgaa cttgcagcag tttctgatga tgccttgatt gaaaaggttg tcaaagccca
    27061 agatgaccgt ctcttctacg tatcagaagc aattcgtcgt ggctacacac ctgaagaaat
    27121 tgcagagctt acaaaaattg atatcttcta tcttgataaa ctcttgcata tctttgaaat
    27181 tgagcaagaa ttgggtgctc atccacaaga tctagaagtt ttgaaaacag ccaaacttaa
    27241 tggtttttca gaccgtaaga ttgctgaact ctggggaacg actgatgata aagttcgcca
    27301 acttcgcttg gaaaacaaga ttgttccagt ttataagatg gtagacactt gtgcggcaga
    27361 gttcgactcc gaaacgccat atttctattc aacctatggt tgggaaaatg aatctatcag
    27421 atctgataaa gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt
    27481 tgagtttgac tacgcaaccg ttcactctgt taaggctatc caggcagctg gttatgaagc
    27541 tatcatcatg aactcaaacc cagagaccgt ttcaacagac ttctctgtat cagataagct
    27601 ttactttgag ccattgacat tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa
    27661 gggagttatc gttcagttcg gtggtcaaac agccatcaac cttgcggagc cattggcaaa
    27721 agcaggtgtg accatccttg gtacacaggt tgctgaccta gaccgtgccg aagaccgtga
    27781 cctcttcgag caagctctca aagaattgga tattccacag ccaccaggac aaacggctac
    27841 caatgaagaa gaagcagctc ttgcagctcg taagattggc ttcccagttc ttgtccgccc
    27901 atcttatgta cttggtggac gtgccatgga aatcgttgaa aacgaagaag accttcgttc
    27961 ttacatgcga actgctgtta aggctagtcc agatcaccca gttcttgtcg actcttatat
    28021 cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt aaagatgtgc tcattcctgg
    28081 tatcatggag catatcgaac gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc
    28141 accacaaacc ttgtcgcaaa aggttcagga gaccatcgca gactacacca aacgcttagc
    28201 aatcggtctt cactgccttg gaatgatgaa catccagttt gttatcaagg atgaaaaagt
    28261 ctacgttatt gaggtcaatc cacgtgccag ccgtactgtt ccattcctat ctaaggtaac
    28321 caatattcct atggctcaag tagcgaccaa gctcattctt ggtcaaagtt tatcagaact
    28381 tggctaccaa aatggacttt accctgaaag cacccgtgtt catatcaagg cacctgtctt
    28441 ctcctttacc aaactagcta aggtagacag cttgctcggt cctgaaatga agtcaacagg
    28501 tgaagttatg ggttctgatg ctactttgga aaaagctctc tataaagcct ttgaagcttc
    28561 ttatctacac ttgccaactt ttggtaatgt cgtctttacc atcgctgatg atgccaaaga
    28621 agaagccttg aacttggctc gtcgtttcca aaacattggt tatggaatcc ttgcgacaga
    28681 agggacagca gccttctttg ctagtcatgg cttgcaagcc caacctgttg gtaagattgg
    28741 tgatgacgat aaggatatcc caagttttgt acgcaaagga agaattcaag ctatcattaa
    28801 cacagtagga acaaaacgaa ctgctgacga agatggtgag caaattcgtc gttcagccat
    28861 tgaacacggg gtgcccctct tcacagcgct agatacagct aatgccatgc ttaaggtact
    28921 tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa aaataagata tagcagactg
    28981 aatttagaac agtacacagg aatactaaaa tatttctata aattaatttg aattttctaa
    29041 ttgatttgtt cgcatcttat ttcaatctac tatagaaaaa agtctttaaa attataaaac
    29101 gcatcatatc aaggtttttc aaaaaccttg atatgatgcg ttttattgtg ggaatatgta
    29161 tttcattttc tactaaaatt atgtttttga ataacctcta tcttagtagt ttgtataatc
    29221 cccctcaatc agtttttgcg ataagcttta atgctatgac tataccactc ttgcatttct
    29281 tttgatggtg gtgtcatata atcgccatac atctgggtta aaaattggtc atattttttg
    29341 ggaacaggca acatacggcc ctcaaactca gttaaaatca gttctttaaa ggtatcaact
    29401 gggaagattt ctttcatccc ttccttaccg atcccaactc ctccttcata ttgaggaatg
    29461 ttggttacag catttttgac tagttgatca attttcttgt aaaagtagcg aggattgaca
    29521 aatcggagag cgtaccagct acataatcta agaaaatctt ttagtttgct atcaccgtga
    29581 actgctcgtg attttttgat ataagctagt tgacgaagag ccacatactt atagctcttg
    29641 tcgacaatgc tcaagtctgt aaatcgatca attgggaaga catcgatgaa aaggctggta
    29701 tcatgacgct tgtacttaac atggtcttct ataacagtag aagtgtccaa aatcgatgcg
    29761 aaattatgga agtaccaaga agatgtatcg taggaaagaa ccttgtagcg agggtgattt
    29821 tcttcttcaa taatcttcag taaacgctca taatcctcac gataaaggga aatatcaata
    29881 tcatcatccc aaggaatcat acctttgtgg cggatggctc caagcatggt tccataactg
    29941 agaaaataag gaatatcatg tttcttacaa gtctcatcaa tatagtccag cagggctagt
    30001 tgaatttctt taatttcttt tttttctaaa tattgcatcc taatcctcca atttataagc
    30061 gtgaaattca tgactgtaga agcgtttttc ttctggtggt agggtcatat aatctccata
    30121 aaattgtgtc aaaatagtat caaatttttc aggtgcagga aggcttaaat tctcaaaggg
    30181 taaatcgatt gttttatcaa aggtaccact tgggaagact tccttttcct taaattttga
    30241 agggataaaa gccatatact gcccattttc acgactatat ttttgaattt ctttctcgat
    30301 tttatttgca aaataacgag gagaaactgg tcgaaggagc aaccaaaagg ctgttcgtat
    30361 ccaatctttt aaaaggctat ccttatagac aatattttta tgtttactga aagacagcag
    30421 tttgaagctt tccagtttat aacaagtatc aatgacctta ggatcatcaa agcgatctat
    30481 agggaaaata tcgataaaga taccagactc ataggttttt gtatttcgag tatcaataat
    30541 tttagtcgta ctgtcggtta tcttgataaa gttgttaaag tagttcttat cagtttctaa
    30601 ggataggagc ttatacttgc ttttttcctt ttgaaaaatg ttaataaatc gttggtagtc
    30661 ttctctaggc atggataaat caatatcgtc gtcccaaggg ataaagccct catgtcgaac
    30721 cgccccaatc agagtaccgt agttaataat atagttgata ttgtgctttt tacagagagt
    30781 atcaatataa tccaaaattt ctaattcaat ttgtttggca tcttcaatgg ttagttgttt
    30841 cattttaaac tcctatgatt ttttgaattt attttttaag gctaggacat ggtttaaaaa
    30901 ttcatagaaa atgctatctt ttgtgaagac aagtagacta atataagaga tagctgatag
    30961 caagacaatc aaaccagtat taattaaaaa tggcaaatta atgaccatat ccacaggata
    31021 cacgaaatta atcaggaaat aaattgctac aaaggaaagt gaaaagagag agtatcgaac
    31081 agtatagcta aagatatgtc ccaagtggat gagttgtttt ctatggatga aaataatata
    31141 gaaaacaagt agagaagtct ctgataacat agttgtcagt aagtagtatt caggaaccac
    31201 gatatggttg aaaaagagga gactattcaa gcccaaattg agtagcccag caaagactgt
    31261 atagactgtg atacgttttt catagccatt ggtaaagaga atttgggaac caagaatggt
    31321 atctaaggcc aggataatcg tacgaaaagc gaagagagag gtcaagatgc cgcctccgat
    31381 atatttttca ctaccgtaaa gtaggatggc atttggtcct aaaaccatga gtccaaaact
    31441 cagtggaatg ataaagaagt taaagattcg actacctcta ttaaccagag aaacataggc
    31501 ttctttgtct cctttcccca gatagtaact gagacgaggc acactcactc caattgcacc
    31561 tgttacaacc ccagctataa cggtcacaat tcgctgagct atggtatagt aactaacgtt
    31621 gacatcaatc cctgttttaa cgaggaagag gcgatctaaa aaagtgaaga gcatattggc
    31681 attggcaaag actaacatgg ctgtcagagg gagaaagagt ggtttaaaat cacttaggtg
    31741 aatcttaaca agtttgatgt ctcttttaat ccaaaaataa ctaatcaggt agttaatcag
    31801 cgtcgataaa ctcatcacaa gtgtatagac aacaatatcg tgttcatttt taacaaataa
    31861 gaaaatagag accagcatca ggatacggat gaaggcagtt ttgtaaaaga gaaaactgta
    31921 attttccaga gcttcattga cccattcgat tgaaaaaatc tgggcaatga gttgaatccc
    31981 cataacaagg tagacctttt tgacgattgg attatcaata aagaagagag gataggctag
    32041 gatatagaca gcagtggtca aaatcgtaca agcgatgcac aaataaaaaa gactagaaaa
    32101 ggttctgtta agatcttttt tgttatcctt gacattactg atagccctta aaccgtagtt
    32161 atagacacca taagttgcaa agggcaagaa aaatgacaaa atagtgtcga ctgagttgaa
    32221 gtaaccatag tcagttcggt ccaagacacg cgcgacatag gttccagtta ggatgggaaa
    32281 aataatattc aagacacgaa ttcccatgta agatagagca tttaatttta tacttttcat
    32341 tcaatttacc tcgtttttca ttatatcata aagttagcta ataagaaatg aagggcagta
    32401 agtcaagtaa tcactttgaa gtttcaaatc ttaagtttta agttttcttt aaggaaagta
    32461 tattattctg aaggactcta aaatttcgca gccatttatt agtaattgct acagaattcc
    32521 tagtcattac tagaaatgga ctagtttctt tgaataatag aactgcataa ttctcctatt
    32581 ctagaagggg aggaccagta tttcttttat gataggacta gattgtggta taatagagag
    32641 aataagtttt tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg
    32701 gtggaactgg cacacgcatg gggatcagta acttgccaaa acaattttta gagctaggtg
    32761 atcgacctat tttgattcat acaattgaaa aatttgtctt ggagccaagt attgaaaaaa
    32821 ttgtagttgg tgttcatgga gactgggttt ctcatgcaga agatcttgta gataaatatc
    32881 ttcctcttta taaggaacgt atcatcatta caaagggtgg tgctgaccgc aatacaagta
    32941 ttaagaaaat cattgaagcc attgatgctt atcgtccgct tactccagag gatatcgttg
    33001 ttacccacga ttctgttcgt ccatttatta cacttcgcat gattcaggac aatatccaac
    33061 ttgcccaaaa tcatgacgca gtggacacag tggtagaagc agttgatact atcgttgaaa
    33121 gtaccaatgg tcaatttatt acagatattc caaatcgtgc tcacctttat caaggacaaa
    33181 cacctcaaac attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag
    33241 agaaggaaat cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct
    33301 tggccaaagg tgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa
    33361 aaagtatgat tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaagcct
    33421 aagtttatca atgtcaaata tcaggaagag gctattgacc aagagaatca tatccttatc
    33481 cgtcccaact acatggctgt ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat
    33541 cccaagattt tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc
    33601 atttctgacc cgaccggaac ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag
    33661 tctcctatgc agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg
    33721 tctagtggat ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg
    33781 gcttatgatg ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg
    33841 cacgctatga atcgtctatt gactcttgct catagcaagc gggagcggat cgccgttatt
    33901 ggagatggaa gtttagcttt tgtggttgcc aatattatca actatacttt gccagaatca
    33961 gagattgtgg ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa
    34021 tgctatatta cggataatat tcctgaagag ttggcctttg accatgcttt tgaatgttgt
    34081 ggtggtgatg gtactggacc agctattaat gacttgattc gctacattcg tcctcaggga
    34141 acgattctca tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta
    34201 gaaaagggct tgattttggt tgggtcatct cgttctggtc gcattgattt taaaaatgct
    34261 atccaaatga tggaagtcaa gaaatttgcc aatcgtctta aaaatatcct ttatctagaa
    34321 gaacctgtaa gagaaattaa agatattcat cgtgtctttg caaccgattt aaacacagcc
    34381 tttaaaacag tgtttaagtg ggaagtataa gtactggagg ttaattgtgg agaaaatcat
    34441 taaagaaaaa atttcttcct tacttagtca agaagaggaa gtcctcagtg ttgaacaact
    34501 gggtggaatg accaatcaaa actatttggt caaaacaaca aataagcaat acattgttaa
    34561 attctttggt aaagggacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga
    34621 actactaaag gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggtat
    34681 caaagtaaat gagtatatcg aatctgcgat tacgcttgat tcaacgtcaa tcaagaccaa
    34741 gttcgacaaa attgctccaa tattacaaac tattcataca tctgctaagg aattaagagg
    34801 agaatttgct ccttttgaag aaatcaaaaa atacgaatcc ttggttgaag aacaaattcc
    34861 ttatgccaac tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga
    34921 cttaggtgtt gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc
    34981 acctcaagga cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg
    35041 ggatttggct gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt
    35101 atctcactat gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat
    35161 tttacaagat actatttgga gtctatggac tgtatataag gaagagcaag gtgaagattt
    35221 tggtgactat ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg
    35281 ttcagatgaa aagtaaaaac ggagttcctt ttggccttct atcaggtatt ttctggggct
    35341 tgggtctaac ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg
    35401 tggctgcagc tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag
    35461 aagggaaagt tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag
    35521 ccttgctagc aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa
    35581 gttctttagc ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct
    35641 tctttttgaa gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag
    35701 ggattattgc ccagacctat aaggttgaac aggttaattc cttctacatt gggattctct
    35761 gtgctttggt ttgtgctatt gcatggggaa gtgagagtgt tcttagctcc tttgctatgg
    35821 aaagtgaact gagtgaaatc gaagccctct taatccgtca agtgacttcg ttcttgtcct
    35881 atcttgtgat tgtgctcttc tctcatcagt catttactgc agtagccaat ggacaattgc
    35941 taggtctcat gattgttttt gcagcctttg atatgatttc ctacttggct tattatatcg
    36001 ctatcaatcg cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga
    36061 cagtcttgtt tgcagttgtt ttcttgggtg caccgctaga tatgctgaca attatgacgt
    36121 cacttgtcgt cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa
    36181 agccatcatc ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc
    36241 taaagccttg gttcaggtta atcaaaaacc tttgattgaa taccaaattg agtttctcaa
    36301 agaaaaagga atcaatgaca tcatcatcat tgttggttat cttaaagaac aattcgatta
    36361 cttgaaagag aaatacggtg ttcgtctcgt tttcaatgat aaatacgctg actacaataa
    36421 cttttactct ctctatcttg taaaagaaga attagccaat agttatgtta tcgatgccga
    36481 taactatctc tttaaaaata tgttccgcaa tgatttgaca cgttctactt attttagtgt
    36541 ctatcgtgaa gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca
    36601 aaacattatt gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc
    36661 tccaacagca gaaaagattg tcagctttat cgataaggct tatgcaagcg gcgaatttgt
    36721 tgatctctat tgggacaata tggttaagga taacatcaaa gagctagatg tctatgttga
    36781 agaattagaa ggcaatagca tttatgagat tgatagtgtc caagactatc ataaattaga
    36841 agaaattctt aaaaacgaaa attaaaagct tccaacatct gacaaaatag tcggatgttt
    36901 ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa atggagttat
    36961 ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac
    37021 agattttgaa agttctagaa tacggtgaaa atgttgatca ggagcttttg ttgggtgata
    37081 ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat tttcagatag
    37141 acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt ttagatgact
    37201 gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt tacaagggaa
    37261 atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac
    37321 agggagctaa atcagttgaa aaagtcattc aaggcttgga aaatgaactg gttattgtca
    37381 gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag aatggcggaa
    37441 aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc aataaacgct
    37501 tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct ggcgaacaac
    37561 ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt cgtggtgtga
    37621 ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga gcaatggaag
    37681 aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc
    37741 atcatttgat tcaagaagga gcaaaattgg tcaccagtgg gcaagatgtt cttgcggaat
    37801 ttgaatttta aaaatgacct aagctaaaat tctaagaaaa aatcaatttt aagagaaaat
    37861 gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt gataatatgc
    37921 gttttttcta agtggattag tagagtagag gatttttctc atataatact cttcgaaaat
    37981 ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg
    38041 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag cttcctagtt
    38101 tgcgctttga ttttcattga gtataaggga aagtatagtg aattgaaata agatgtgaac
    38161 aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa ggtgcactgt
    38221 tatagattca atacactata atttagtgta attgagaaag gagaaatgat tgtgattgat
    38281 gttggctagg ttatgttcaa tgattcctac cgtctcaaat cttgtcagta aggaaaaata
    38341 aattcttcaa aagtagagat tacaaggttt gtttaagaaa gaattcaaag accttgacaa
    38401 ataaaaataa aatggttatt ataagaaatg gtctaaaata gatgatgata cttttcgaaa
    38461 atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac ggttagcttc
    38521 cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta gacatttgag
    38581 tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca gactactaaa
    38641 gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat atttgtgaca
    38701 aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga attagaactt
    38761 tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat cggattaaat
    38821 atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat gacacctatt
    38881 ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa atcttttaaa
    38941 atattagcta ttcaaattct tgccagtcta atagcttcaa cactttattt ttatctttct
    39001 cccatttcgt atgctagttc ggagattgtt gctagaacct ctccgactat ttgggatgtt
    39061 ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa agagaccaat
    39121 aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg tacagtaggt
    39181 tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct attcctcatc
    39241 aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat ggttaagaaa
    39301 cattatttta aagataatga agaagactct aaaatgcgta ggattttgct tctagttgct
    39361 gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga aacgttgaaa
    39421 aaagagtccc ttaagaaatt tatatcagag cagtttcagg ggcataatat tttgaaaaaa
    39481 acctattcta aaaagactca taccctaaag ctaaccatct caggaaatta tttgacagaa
    39541 gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga tgtttctgtt
    39601 caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt ggagtatttc
    39661 ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagctaataa atttgataca
    39721 gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt cttctatgta
    39781 tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag tagctaagtc
    39841 ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga aaaggtgtga
    39901 tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc tagtcatcgt
    39961 ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact acaaggtttt
    40021 agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg atattgaaaa
    40081 taattatgaa ccgcaatata ttaatatccg aggaaaaggc cctcttatca atgacttgaa
    40141 aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc gtgaaggaga
    40201 agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg ccaaccgtgt
    40261 ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac ctcgtaagat
    40321 agatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct tggtagggta
    40381 ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag gtcgcgttca
    40441 gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct tccagccaga
    40501 agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc atgcttcctt
    40561 ctatggagta gatggtaaaa agatgaaact gaccagcaat gatgaagtca aggaagtctt
    40621 gtctcgtctg acgagtaaag acttttcagt agatcaggtg gataagaaag agcgcaagcg
    40681 caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca ataaaatcaa
    40741 tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa ttaatatcgg
    40801 ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta tcagtcctgt
    40861 agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagtaagt attctaagca
    40921 cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta ttcgtccgtc
    40981 aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc agctcaagct
    41041 atataccctt atctggaatc gttttgtggc tagccagatg acagcggccg tttttgatac
    41101 catggctgtt aaattgtctc aaaaaggggt tcaatttgct gccaatggta gtcaggttaa
    41161 gtttgatggt tatcttgcca tttataatga ttctgacaag aataaaatgc taccagatat
    41221 ggctgttgga gatgtggtca aacaggttaa tagcaaacca gagcaacatt tcacccaacc
    41281 gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg gggttggacg
    41341 tccatcaacc tatgcgccaa ccattgaaac cattcagaaa cgttattatg ttcgcctggc
    41401 agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca tcgttgaata
    41461 tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac tggatgatgt
    41521 cgaagttgga aaagagcagt ggcgacgggt cattgatgcc ttttacaaac cattctctaa
    41581 agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg aaccagctgg
    41641 atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt ttggtaaatt
    41701 ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga aagagattgg
    41761 tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca agcgtaatcg
    41821 ccttttctat ggttgcaatc gctatccaga atgtgaattt acctcttggg acaagcctgt
    41881 tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc gtggtggtgg
    41941 caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat aagaggaggg
    42001 gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca tcattttatg
    42061 cgaaactaga agaagattat tttaactagg agaagttatg cgtcttatct atctgataat
    42121 tggtttttta tcactggcct tggctattgt tggggttgtt ttacccttgt tgccgacaac
    42181 gcctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgtt tcgaagactg
    42241 gctttatcat accaagctct atcaaacata tgtagctgat tttcgcgaga ctaagtctat
    42301 tacgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg gaatttctat
    42361 ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca tctttatcac
    42421 ttattatctt ttcaaggtca ttccagacaa agaatagtta aaacagtagt tatttgcctt
    42481 gataaaattg aaagcatatt cataataata tgatataata aatttgaagt aatattcaag
    42541 gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga aaaagcgatg
    42601 caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg gacaacaccc
    42661 agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac aaccatcatg
    42721 accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat tgctatcatg
    42781 ctagaagaca ttcgtttgac tgctcaggct ggaagtcaag gggttgtatt tggaacttta
    42841 actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc atcaaaagga
    42901 atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca accggaagct
    42961 attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc
    43021 gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc taaaggtaaa
    43081 attgaaattc taccaggtgg ggggattgac cttgaaaacc gtcaaacctt tatcgaccag
    43141 gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga aaggaactgc
    43201 tagctttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc aatttaatca
    43261 agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat atagttgcca
    43321 gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg tgaactttca
    43381 agtctttgac caagagactg gtgacctcta tcctcacgtt catatggaaa gcatgagggg
    43441 aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga ttcggaaggc
    43501 ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga ctcaagttca
    43561 ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata cagctgtatt
    43621 gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt ggaataagct
    43681 ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc aagtagctaa
    43741 tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct actggattag
    43801 tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag aaaaaagttg
    43861 gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc aattagctga
    43921 atattcttta ctgaagaaat tttcagaaaa tataggattt accacaccag aggaatgtgg
    43981 tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca tctattcgcc
    44041 tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg tcaagaatgg
    44101 tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctgaaa atgctgcttt
    44161 ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag aaaccagtat
    44221 tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg gtattccagt
    44281 tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg gtattcacca
    44341 agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat tggttggtgt
    44401 taagattccg cttggaaaat tatctggtcg ccatgctttt gttgagaaac tgagagaatt
    44461 ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca aggcactggc
    44521 cgataagaag taagaaatca cagatgcaga tactcgagct ttggtagctg gaaccatggt
    44581 tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg cagataatga
    44641 cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat ttaatgcgac
    44701 agggcaaggt tccgttgaag caatctttaa tgctatcgat aagttcttta accaatctgt
    44761 tcgtttggtg tcctacacta tcgatgcggt aacagatgga atcgataccc aggatcgggt
    44821 tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag ggcttgattt
    44881 tgatgtgttg aaggcttctg ctattgtcta tataaacgct aatacctttg ttcaaaaaga
    44941 gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag
    45001 aaggctatgg caaagaaaat agtagctcta gcaggagacg gaattggccc agaaatcatg
    45061 gaggttggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga ctatgagatt
    45121 gacagacgac cgttcggagg tgcagatatt gatgcagcag gacctccctt acctgatgaa
    45181 acccttaagg caagtaggga agcagatgct atcctactag cagctatcgg tagtcctcag
    45241 tatgatggag cagtggttcg ccctgaacag ggcctgatgg ctctccgtaa ggaactcaat
    45301 ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagtattt gtcaccactc
    45361 aaactggaac gaattgctgg tgtagacttt gtcgtggtgc gtgaattgac aggcgggatt
    45421 tactttggag atcatattct tgaagagcgc aatgcgcgtg atatcaacga ctatagctat
    45481 gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc
    45541 cttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg gaaagtagct
    45601 gaggaagtcg cacaggattt cccagatgta accttggaac accagctggt agactcagct
    45661 gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga gaatcttttt
    45721 ggagatattt tatctgatga atcaagcgtc ttatctggta cacttgaggt tatgccatca
    45781 gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacggttc agcacctgat
    45841 attgcaggtc aaggaattgc caatcctact tccatgattt tatcagttgc catgatgttg
    45901 agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt tgagacaagt
    45961 ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa ggaaatgacg
    46021 gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc cttttgattt
    46081 ggaatgtcat cattttcttg atttatggca ttgacaaatt caaggcaaga agaagagctt
    46141 ggcgcatccc agagaaaatc ttactcattt tagcccttac ttgtggtggt tttggggcct
    46201 ggttagctgg aattactttt caccacaaga ctcgaaaatg gtactttaaa acagtttggt
    46261 ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa tggatggcag
    46321 ggtcttcgag ggaacacgct gcttgggctc tagcggacta tggttttaag gtcgtgattg
    46381 caggatcttt cggtgacatt cattacaata atgaactcaa taatggcctg ttgccaatcg
    46441 ttcagcctag agaggttaga gagaaattag cccagctaaa accaaccgac caggtaactg
    46501 tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc gagatagata
    46561 gcgagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc ttgcagtatg
    46621 aagagttgat tgttgcttat gaaaaacaac gaccagccta ctggcaggat tagaaaaaat
    46681 agaaaaggaa atatagtaaa ctgaaataag atgtaaacaa atgaattaga gcttaacatc
    46741 catttccagc aattttttag aaactacagt ggactattct ggattcaaca cattataaaa
    46801 ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg gcggatgtat
    46861 cgtttgccct actaaagttg gttacattat catgaccagc aacaaggcag gacttgagcg
    46921 taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct gcggtagcat
    46981 ggatgaactt tgcgctttag cgcaactcaa cccagaaatt gaagcattct actaaaaaca
    47041 ttgggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag tctttgaaaa
    47101 actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg gtactagctg
    47161 ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt gggaagaagg
    47221 taaaatggtc tacgcctcat ctacttcaat gacaaaacga ttgaaactcg ctatgagagc
    47281 aaggtgtaat ggtgtctatg gtcgataagg acggcaaact catcccagaa caaggaggag
    47341 cacgttcaac ctcaccagca ccagttgtga tccgtaaagg gcttgacatt gataaaatca
    47401 tgatgcacct gtcagatact tttaactcat gggactaccg tcaggttgag tattattagg
    47461 atagagaaga agtctagtgt taaggacatt acagctcata atactaggct tttttataga
    47521 aattcttttc tttttctata ggatatggta ttctatgtag aaaatatatg ttaataagta
    47581 atgccaatat ttaaacatca ttagtaaaag gagttagatt gatgaataaa agaaaagtta
    47641 gtttagaaga tttttataaa tggtatagtc taaataaaga agagttatta aataaggcaa
    47701 ctgttggtga aaagtttaat gataaattaa aagaagagtt tctccaggaa tggcctttgg
    47761 ataggatttt aacaatgtca atcgatgaat atgtaatagg aaagggacag caaaataagt
    47821 ctttatgcta cgctcttgag aagggaaaat acaaaaatct atttcttgga atttctggtg
    47881 gctcagcttc aaaatttggt atttattgga ataaaaaaac aaacaaatat aaagatcaag
    47941 ctaataatga gatttcagag ttggatcagc gattttcaaa attaaaatca gatttgtatg
    48001 aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat atgaaaagat
    48061 caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt atctattctg
    48121 ggggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg aaccactttg
    48181 tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt gaactggtgt
    48241 ccaaaactta tcctgagttg gagccatcga aattaggaac tatgcttttt gagtattcta
    48301 agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac aattttcgtc
    48361 atcaattaac tcaatctcta ttaaagtctc caaaccttat ccttcgtggt gctcctggca
    48421 caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc aacgaagacc
    48481 aaatcggatt tgtacaattt cacccatcct atgattatac ggattttgta gaaggtttaa
    48541 gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt atttttaaag
    48601 atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat tttgatgagg
    48661 cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat ataacaaaaa
    48721 catcttactt atctgttaat agtagacaaa atttgtcagt aaattatgat agtggtgttc
    48781 caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa aattataata
    48841 agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga aagagatttg
    48901 gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc gtcttcatca
    48961 tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt ttctctatcg
    49021 accctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat ctacacgaaa
    49081 ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg aatgatattg
    49141 atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta
    49201 ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca gaagaagcaa
    49261 aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt
    49321 atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac tatgaattac
    49381 tctggtccga ttatattaag cctctcctag aagactactt gcgaggttct tatgatgagg
    49441 ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgat caaactggtc
    49501 aacaagatac tggtgataat gatgcggatt actgataatc aatacaagat tattaaagaa
    49561 aaatttgttg aagaatatcc gaaactaagc aatcttcttt tagacagaac cttggaaagt
    49621 ctatcccaag atgaacgtat tttcattttt ccaaatgatt tgactcatac tcctgatttg
    49681 gataaggacc aaaagatttt tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt
    49741 ggttttcttg gatatggtca ggaaagatta acgatttcct cacgattttc tgatgagagt
    49801 aatgaccatt ttttgcatta tctcttaaac aaggttcttc atatcaatct cactagttta
    49861 gatgttgctt tgtctcgtga agagaggctt tatcaacttt tgatgtatct cttccccaag
    49921 tatctacaag ctgctattcg aaaaggtctt tataaggaat accagagatt ttctcataac
    49981 gacagtcatg ttaagggagt gattgatgta agaaaccatc tcaagaaaaa tcttcctttc
    50041 acgggaaata ttgcctacac aacgagagag ttcacctatg ataatcccct catgcagttg
    50101 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    50161 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    50221 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    50281 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    50341 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    50401 gaagagtatg tttacacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    50461 acggatggaa tttcagtatt ttctgttggg aaactaaaag tatatccaga tttttatgac
    50521 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    50581 atcaaccgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    50641 gctggactga tttttcctag tatggagcag tcagtaaata gtgaaatagg aaaagtagct
    50701 ggctatggag ctcaattgaa gaagtggtct attcgaatcc ctcagaatgc ctcattctat
    50761 agtacatttt gtaaaatgat ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa
    50821 gaagtgggga gaaaataatt tcccctcttt cttttatttt taacacaagt aaaacccgaa
    50881 cgatatattt taattcataa aataatttga caaaaactgt actttggttt ataataaatt
    50941 aaggaaacgt cggaaaaggc gtagtgatgc aagagcatag gtaggtcatt acaaaagaaa
    51001 cgagacatcg atatgttaaa tgaatttcca atttttgatt acgaagatat tcaattgatt
    51061 ccaaataaat gtgtcattaa aagccgtgca gaagcggata caagtgtcac tttaggaaat
    51121 cacaccttta aactacctgt tgtgccagcg aatatgcaga cgattttgga tgaaaatgta
    51181 gcagagcaac tggctaaagg tggttacttc tacattatgc accgttttga tgaggcagga
    51241 cgcattcctt ttattaaacg aatgcacgat caagggctca ttgcttctat ctctgtcggt
    51301 gttaaggatt atgagtatga tttcgttaga cagctcaaag ctgatgctcc tgagtatatc
    51361 actattgata ttgctcatgg tcatgcggat agcgtgattt ctatgattca acacatcaag
    51421 aaagaattgc cagatacctt tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt
    51481 gaattggaaa atgctggtgc ggatgctact aaggtcggaa tcggtcctgg taaggtttgt
    51541 atcaccaagg ttaagactgg ttttggtaca ggtggttggc agttggctgc tctacgctgg
    51601 tgtgccaagg ctgcgcgtaa accgattatc gctgatggag gaattcgtac tcacggtgat
    51661 attgctaagt ctatccgctt cggtgctagc atgatcatga ttggttccct ctttgcagga
    51721 cacattgaaa gtccagggaa aacgattgaa gtcgatggtg aacagttcaa agaatattat
    51781 ggttcagcct cacaatatca aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg
    51841 cttcctgcta aaggtcatct gcaagacact ttaactgaga tggaacaaga ccttcaaagt
    51901 gctatttctt atgcaggtgg acgtcaggtt gctgacctta aacacgttga ttatgtgatc
    51961 gtgaaaaact ccatctggaa tggggatgct tcccactaag acggggtctt tgaccaaaaa
    52021 acttgttatt agagcaaatt tctgttataa taaaacaagt ttccaccctt agtgtaatgg
    52081 atatcacgta agattccggt tcttgagatg ggggttcgat tccctcaggg tggatgtaaa
    52141 catcctaaaa agcctttaat agggcttttt tctttatcct gacccaaatt tgccgctaaa
    52201 actgagaatc tctgtctaaa gaattcccaa atgctttcca gtcccgtttt agagtgactc
    52261 agggggcttt ttttgatata ataaaaagga ctattatcag ttagaaagag gttggtatga
    52321 aagaattaca aactgtacta aagaatcatt ttgcaatcga atttgcagac aaaaatttac
    52381 tggaaactgc ctttactcat acgagttatg ccaatgagca ccgcctctta aaaatttcac
    52441 acaatgaacg cttggaattt ttaggagacg ctgttctaca gttattgatt tcagaatatc
    52501 tatataaaaa atatcctaaa aagcctgaag gtgacctatc aaaactccgt gctatgattg
    52561 tccgtgagga gagtttagct ggttttgcgc gtgattgcca gtttaaccag tttatcaagt
    52621 tgggtaaagg ggaagaaaaa tcaggtggtc gcaatcgtga caccattctt ggtgatgcct
    52681 ttgaagcctt tcttggtgcc cttcttttgg ataaggatgt ggccaaggtc aaggaattta
    52741 tctatcaagt catcattcct aaggttgaag caggcgagtt tgagatgatt acagactata
    52801 aaacccatct ccaagagttg cttcaggtca atggtgatgt ggctattcgt tatcaggtga
    52861 tttctgaaac agggcctgct catgataagg tctttgatgt agaagttctt gttgaaggta
    52921 agagcatcgg tcaaggccaa ggtcgttcta agaaattagc agagcaggaa gctgccaaaa
    52981 atgccgttga gaaggggctg gattcatgta tttaaaggaa atcgaaattc aggggttcaa
    53041 gtcttttgct gataagacca aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc
    53101 caatggatct ggaaagtcca atattacaga aagtctgcgt tgggctttgg gggagtctag
    53161 tgtcaagagt ctccgtgggg gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg
    53221 caaaccgctc aattatgctt ctgtagttgt gactctggat aatcatgacg gatttatcaa
    53281 ggatgcaggt caagaaatca gggtggaacg ccatatctat cgtagtggag atagcgaata
    53341 caagattgac ggcaagaaag tccgtctgcg tgatattcat gacctcttct tggatactgg
    53401 attgggacga gattccttct ctattatttc ccaagggaag gttgaggaga tttttaattc
    53461 caagcctgag gaacgacgag ctatttttga agaagctgct ggagttttaa aatacaagac
    53521 tcgcagaaaa gaaaccgaga gtaaactgca gcaaactcag gataatctgg accgcttaga
    53581 ggacattatc tacgagttgg ataatcaaat caagcctctt gagaagcaag ctgagaatgc
    53641 ccgtaagttt ttagacttgg aaggacaacg taaggctatt tatttagacg ttctggttgc
    53701 tcaaatcaag gaaaataagg ctgaactaga gtcgacagaa gaagagttga ctcaggttca
    53761 agaactcttg atgagttatt accaaaagcg tgaaaaatta gaagaagaaa atcaaactct
    53821 taaaaagcaa cgccaagatt tacaggctga aatggccaaa gaccaaggca gtttgatgga
    53881 cttgactagt ctgattagtg atttagaaag aaaattagcc ctatcgaaac tggagtccga
    53941 gcaagtggcc ttgaatcaac aggaggcaca agcccgtttg gctgctttgg aggataagag
    54001 aaattcactc agcaaagaaa agtctgataa agaaagctct ttagctctgt tagagggaaa
    54061 tctagtccaa aataatcaaa aactcaatcg tttagaagct gaattgctgg ctttttcaga
    54121 tgatcctgat cagatgattg agcttttgcg tgaacgcttt gtggcgcttt tacaagaaga
    54181 agcggatgtc tcaaaccaac tgacccgcat cgagaatgag ttggaaaata gtcgtcagct
    54241 ttctcaaaaa caagcagatc aactagaaaa gctgaaagag caattggcta tagctaaaga
    54301 gaaggctagt cagcaaaagg aagagcttga aactgccaag gagcaggttc agaaattatt
    54361 ggctgactat caagctattg ccaaggagca agaggagcaa aaaacttcct atcaagctca
    54421 acaaagtcaa ctctttgacc gtctggatag tcttaaaaac aagcaggcta gagctcaaag
    54481 tttggaaaac atccttagaa atcacagtaa cttttatgca ggtgtaaaga gtgttctcca
    54541 agaaaaagac cgccttggtg ggattattgg tgctgttagt gagcatttga cctttgatgt
    54601 gcattatcaa actgccttag agattgcact tggagccagc agtcagcata tcatcgtaga
    54661 agatgaagag tcggcaacca aagctattga tttccttaaa cgaaacagag ccggtcgtgc
    54721 aaccttcctt ccgttgacaa caatcaaggc tcgtacgatt tctagccaga atcaagatgt
    54781 tatcgctgta agcccaggtt tccttgggat ggcagatgag ttggtgactt ttgatactag
    54841 actggaagcc attttcaaga atttgctagc tacgacggct atttttgata ctgtagagca
    54901 tgcgcgtgca gcagctcgcc aagttcgtta tcaggttcgt atggtgacat tggatgggac
    54961 agaattacgc acgggtggtt cctatgcggg tggtgccaat cgccaaaata acagtatttt
    55021 catcaagcca gaactggagc aattacaaaa agaaattgct gcagatgaag caagcttggg
    55081 ttcagaagaa gcggctttga agaccttgca agaccagatg gctacattga cagaaagatt
    55141 agaagccatc aaatctcaag gagaacaggc acgtattcag gagcaaggct tgtccctcgc
    55201 ttatcagcaa actagtcagc aagttgaaga actggaaact ctttggaaac tccaagaaga
    55261 ggaaaaagat cgtctttctg atggagattg gcaagcagac aaggaaaact gccaagagcg
    55321 tcttgctgca atcgccagtg acaagcaaaa tctggaagct gagattgaag agattaagtc
    55381 taataaaaat gccatccaag aacgctatca aaacttgcag gaagagctag cgcaagctcg
    55441 tttgcttaag acagaactgc aagggcaaaa acgttatgaa gtggctgata ttgaacgctt
    55501 aggcaaggaa ttggacaatc ttgattttga acaagaggaa atccagcgcc ttcttcaaga
    55561 aaaggttgac aatcttgaga aggttgatac agaattgctc agtcaacagg cggaagaatc
    55621 caaaactcag aaaacgaact tccaacaagg tttgattcgc aaacagtttg agttggatga
    55681 tatagaaggt cagctggatg atattgctag tcatttggat caggctcgcc agcagaatga
    55741 ggagtggatt cgcaagcaaa cacgtgctga agccaagaaa gaaaaggtca gcgagcgctt
    55801 gcgccatcta caaagtcaat taacagacca gtaccagatt agctatactg aagctctaga
    55861 aaaagcgcat gaattggaaa acctcaatct ggcagagcaa gaagttaagg atttagagaa
    55921 ggctattcgc tcactgggtc ctgtcaatat agaagctatt gaccagtacg aagaagttca
    55981 cagccgtctg gatttcctca atagccagcg agatgacatt ttgtcagcga aaaatctgct
    56041 tcttgagact attacagaga tgaatgatga ggtcaaggaa cgctttaaat caacctttga
    56101 agctatccgt gagtccttta aagtgacctt caagcagatg tttggcggag gtcaagcgga
    56161 cctgattttg actgagggag acttgctgac agctggggtt gagatttctg ttcaacctca
    56221 aggtaagaaa atccagtccc ttaatctcat gagtggtggt gaaaaagctc tatcggctct
    56281 tgccttgctc ttctccatta ttcgtgtcaa gactattcca tttgttatct tggatgaggt
    56341 ggaagctgcg ctggatgaag ccaatgttaa acgttttggg gattacctca accgctttga
    56401 caaggacagc cagtttatcg tcgtaaccca ccgtaaggga accatggcag cggctgattc
    56461 catctatgga gtgaccatgc aagaatcggg tgtttcaaag attgtttcag ttaagttaaa
    56521 agatttagaa agtattgaag gatgacaatt aaactagtag caacggatat ggacggaacc
    56581 ttcctagatg ggaatggacg ctttgatatg gatcgtctca agtctctctt ggcttcctac
    56641 aaggaaaaag ggatttactt tgcggtggct tcgggtcggg gatttctgtc tctggaaaaa
    56701 ttatttgctg atgttcgtga tgacattatt ttcatcgcgg aaaatggcag tttggtagag
    56761 tatcaaggtc aggacttgta tgaagcgact atgtctcgtg acttttatct ggcaactttt
    56821 gaaaagctga aaacgtcacc ttatgtagat atcaataaac tgctcttgac gggtaagaag
    56881 gggtcatatg ttctagatac ggttgatgag acctatttga aagtgagtca gcattataat
    56941 gaaaatatcc aaaaagtagc gagtttggaa gatatcacag atgacatttt caaatttaca
    57001 accaacttca cagaagaaac gttagaagct ggtgaagctt gggtcaatga taatgtccct
    57061 ggtgtcaagg ctatgacaac tggctttgaa tctattgata ttgttctgga ctatgtcgat
    57121 aagggtgtag ctattgttga attagctaaa aaacttggta tcacaatgga tcaggtcatg
    57181 gcttttggag acaatcttaa tgacttacat atgatgcagg ttgtgggaca tcctgtagct
    57241 cctgaaaatg cacgacctga aattttagaa ttagcaaaga ctgtgattgg tcaccataag
    57301 gaacggtcgg ttatagctta tatggagggc ttataatggc agatataaaa ttgattgcat
    57361 tggacttgga cgggaccttg ctgactactg ataaaaggct gacggatcgt accaagtcaa
    57421 ccttgaaagc tgcgcgtgat cgtggtatca aggtcgtatt gacaactggt cgtcccttaa
    57481 aagccatgga tttctttctc catgagttag ggactgacgg tcaggaagat gagtatacca
    57541 ttacttttaa tggtggatta gttcagaaaa atacaggaga aatccttgat aaaacagtct
    57601 tttcatatga tgatgtggca cgtttgtatg aagaaacaga gaaattatca ctgcctcttg
    57661 atgccatctc agaaggaaca gtttatcaaa tccaatcgga ccaagaaagt ctttatgcca
    57721 aattcaatcc agctttgact tttgttccag ttgactttga agacctgtct agtcaaatga
    57781 cctacaacaa atgcgtgacc gcctttgctc aagaaccctt ggatgcagcc attcagaaga
    57841 tttctctaga attgtttgac caatatgaaa tctttaaatc acgtgaaatg ttgctagaat
    57901 ggtcaccaaa gaatgttcat aaagcaacag gtttggcaaa actaatcagc catcttggaa
    57961 tcgaccaaag ccaagtgatg gcttgtggtg acgaggccaa cgacctctct atgattgaat
    58021 gggcaggtct tggtgttgct atgcaaaacg ctgttcctga agtaaaggta gccgcaaatg
    58081 tagtgacgcc gatgaccaac gatgaggaag ctgtcgcctg ggctatcgaa gaatatgtgc
    58141 taaaggagaa ctaagatatg ggattgtttg accgtttatt cggaaaaaaa gaagaaccta
    58201 aaatcgaaga agttgtaaaa gaagctctgg aaaatcttga tttgtctgaa gatgttgatc
    58261 ttaccttcac agaagctgat gaagttcctc aggaagaagc agaggttgaa attgttgaac
    58321 aagctgtgtt ccaagaagag gaaatccaag acacagttga agaaagtcag gattcagagc
    58381 cagctgtagg ggtttctcaa gaagaaatag aagaattacc aaactcagaa gaattaccag
    58441 aggaagagaa gcttgagcac gaaggaactg tagaagaaaa taattctgaa gtgcttgaac
    58501 cagaagctcc tcaaacagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    58561 ctcgcacagg tttcggtgcc cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    58621 aagaattttt cgaggaactg gaagaactgc tgattatgag tgatgttggt gtccaagtcg
    58681 cttctaactt aacggaggaa ctacgttacg aagccaagct tgaaaatgcc aagaaacctg
    58741 atgtacttcg tcgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggtagct
    58801 acgatgaaag catccacttc caagataact tgacagttat gctctttgtt ggtgtgaatg
    58861 gtgttgggaa aacaacttct atcggaaaac tagcccaccg ctacaaacaa gctggtaaga
    58921 aggtcatgct ggttgcagca gataccttcc gtgcgggtgc agtagctcag ctagctgaat
    58981 ggggccgacg agtagatgtt ccagtagtaa ctggacctga aaaagctgat ccagccagcg
    59041 tggtctttga tggtatggaa cgtgccgtgg ctgaaggtat cgatattctc atgattgata
    59101 ctgctggtcg tctgcaaaat aaggataacc ttatggctga gttggaaaag attggtcgta
    59161 ttatcaaacg tgttgtgcca gaagcaccac atgaaacctt cttggcactt gatgcatcaa
    59221 caggtcaaaa tgccctagta caggccaaag aattttcgaa aatcacacct ttaacgggaa
    59281 ttgttttgac taagattgat ggaactgctc gaggaggtgt ggttctagcc attcgtgaag
    59341 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagagt
    59401 ttaactcaga aaactttatg aaaggtctct tggaaggctt aatctaatca gaagcaaaaa
    59461 tcctgcaagg tacaaacttg caggattttt ttattcgaaa cgaccatctt gacgataggc
    59521 gatatctggt tgccaagtcc atttggcacc gaatttttca agtaggtcaa agctggcttg
    59581 aggtcccatg cttccagctt tatagtcatg aagtggggca ccattttcag cccagagctt
    59641 ttcaatacgg tcaatcaact tccatgacgc acaaacttca tcccagtggc taaagttagt
    59701 tgagttgtta tttaggacat cataaatcaa tttttcgtat ggttctggag aagcaccagt
    59761 tgcagtcgca tctgtacggt aatcaagtga gttaggagcc aagttaaatt cttctcctac
    59821 ttgcttccca tttaggctaa gagagaagcc ttctgttggt tgaatataga tggtcaaaat
    59881 atttggagca agtggttctc caaagataga atccatttgt ttaaagacga tgttgacatg
    59941 agttcctttt tcagtcagtc gtttacctgt acggaaaaag aaaggaacac cacggaatcg
    60001 atcgctgtct acaaagaagg caccagatgt aaaggtttca gttgttgatt ctggattcac
    60061 atttggctcg ctacgataag agatgtattt catgccatca atcttaccag agcggtattg
    60121 cccacggata aagtgttctt tgagttcttc atcagttgga tgatagaggt ttttaaagac
    60181 cttaatcttt tcagcacgaa tctcgtcttt tgtgaagctt gctggtttgt ccatggcgag
    60241 gagcgaaaga agttgtagag tgtggttttg gaccatgtca cggagggcac cggattggtc
    60301 atagtagcca ccacgttctt ctacacccaa gcgctccgca aaggtaattt gaacattgtc
    60361 gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt gcaaagcgaa ctgcaaagat
    60421 gctttggatc atttccttac caagataatg gtcgatacgg aaaatttgtt cttcgtcaaa
    60481 tgttgctagg agttcgacat tcaacttgct tgcagttgcg taatctgtac caaatggttt
    60541 ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg ttttcagatt tgaggtgttt
    60601 ggcaatggtt ccaaagaact gaggtgccat agacaagaag aagagcttat tgtgttcagc
    60661 ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa gcaatataat gttccgaatc
    60721 attgacatca tggctttgat agtagaagtg gctagcaaat tcttgggctt gctcggtact
    60781 atctgccaaa tcaaggatgg actcgacaac tacagattca aaatattcct tactccaagg
    60841 tctacgggca gttccaataa cggcaaagtg cttggaaaga ttgccggatt gatatagtct
    60901 aaaaagggaa gggtagagct tgcgtttagc caggtctcca ctcgcaccga aaattgtaac
    60961 aataacctta gatgacatct agctacctaa tttctatttt tattcctagt cttgctaggt
    61021 atgaggaaac ctcatttcat aaacttaatt ctaacataat tttccgaaaa atcaaaaatt
    61081 ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt ttgagtttag acgtttaaga
    61141 ccttatctaa gaactctttc agacgagggt gttgtgggtt atcaaagatt tggtcaggtg
    61201 ttccgtcttc aaggaactcg ccatctgcag taaagataac gcggttggca acctgacgag
    61261 caaatcccat ctcatgggtt acgataatca tggtcatgcc ttgctcagcc aattccttca
    61321 taacgttaag tacgtctcca accatctcag ggtcaagggc agaagttggt tcatcgaaga
    61381 gcatgatgtc tggattcatt gctaggccac gagcgatggc cacacgttgt ttttgaccac
    61441 ctgataggct atctggattg gcattagctt tatctgctag tccaaccttt tcaagcaact
    61501 ccattcccaa ttcctcagct tcttccttag tcatcaactt gtgctcaata ggagcaaagg
    61561 tgatgttgtc caatacagac atatgaggga agaggttgaa gtgttggaat accatgccga
    61621 tattttcacg gacgtggtca acattggttg ttttttcagt taaatcatag ccgttcacag
    61681 tgatgtgacc gctagtgact tcttctaaaa gattgaggct acggaggaaa gttgacttac
    61741 cagaacctga aggaccgatg atacaaacaa catctccttc atagaactta gtcgtaattc
    61801 cttttaggac ttcatttttt ccatagtact tgtgtaaatc atttacatca atttttaatt
    61861 ttgccattaa cgaatcctct tttctaagcg tttcgctagt ctagtcaaaa gtgtgataat
    61921 tacaagatag aagatagcaa ggattgcata catcttgaaa ctttggtagt tacgagcaat
    61981 gataatctta ccagtttgga agagttcaac caaaccgata gcagatacga tagttgtatc
    62041 tttaagagcg ataacgaatt ggttgacaaa gtttggcaac atcaatttag ttgcttgtgg
    62101 caagataatc ttacgcatgg tttttccata agagataccc aagcttcggc tggcttccat
    62161 ttggccaact ggaacggcct gaataccacc acgaacgatt tcagcgatat aagcagccgc
    62221 attgagtgag agggcaattg ttccagctac aaagtcgtta attgggcttt gttggcctgt
    62281 gatagactcg atgaagtttg gaattcccca gaagatgaag gctgcaagaa tcatcaatgg
    62341 aataccacga ataacgtcaa cgaaaatctc agagatgacg cgaagagatt tgtatgggct
    62401 aacgctaaac ataccgaaga taattccgat gacaatggca atagcaaatg agataagagc
    62461 tagagcaaga gtgataccaa gaccgctaag gagttgtttg tagttgtttt gaagcaagcc
    62521 ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt gaagattcgc tagctaggta
    62581 tttgtcaaga atcttttgga attcaccgtt tgctttaagg tttgcaagtc cgttgttgaa
    62641 catttcaatc agttctggat ttgctccttt tttaacggca aaggctgttt caccgattgg
    62701 agttccagag attggagttt tcaatttttg accttggctg atagaatatt tgagaacagg
    62761 ttcatcatcc ataacggcat caatggcacc agtgtttaaa ctgtcataca ttgaagaacc
    62821 atcagcaaag gttttgattt tgtaaccgta tttgctttga ttttctgtta ggaaggtttg
    62881 agaagcagtt ccgtttttaa caccgactgt ctttcctttt agatcttcat aagaagcaat
    62941 attgcttgat tctttgacac caagaatggt attagcagtg tagtatgatt ctgagaagtc
    63001 aaaagttgcc ttacgagcat ctgtgacaga cataccagca atgataccat cggcttgacc
    63061 agcttggaca gcactgatag cagcatcaaa accagggttg gtgatttcaa tttcaaaacc
    63121 ttggtcttta gcgattgcct taatcaattc catatcaata ccagtgtatt ggttgcttga
    63181 attttggaaa acaaaaggtg caaaagaaga atcgctggca atgatatatt tagccttaac
    63241 aggaatagct tttaatcctg cgagagtagt tgtagttggc actgctgaag atgatgaagc
    63301 agtccatttc ttgataattt tatcaagact accatctttt ttcatttcag acaaggcttg
    63361 gttaaattca gtaaccaggt gctcgtattt acttcctttt ttcacaccga aagcaaaact
    63421 tcctacagct tcaccatcca tttcaatatg gaggtcttga ccttggttaa tggcatattc
    63481 gataacaggt ttgtcatcca tcatggcatc gatggcacca gcactcaagc tgttgttcat
    63541 taaatcacca gtgtcaaatg ttttaatagt aaagccgtat ttatctttga ttgtttcaag
    63601 gaaacgttga gcggcagttc cgtttttaac accaacggtt ttgccagtta attggtcgta
    63661 cttgctaatt ttgtgtgact ttgtagtagc aatgacaact tttgtatcat agtaagtatc
    63721 agacatggtg aagacttttt cacgttcttt agtctttgtc atccctgcca tgatagcgtc
    63781 ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat ccaggatagg acatctgaat
    63841 gttccagcct ttaatctcag cgactttgtt aataatgtca acatcaattc ctttataagt
    63901 ttgatctgaa tctttaaact caaaaggtgc ataggcggta tcagaaacaa tcttaatcgt
    63961 ttctgctttg gcaataccta atgagaaaat tgggaataaa attagcaaaa atgctagaaa
    64021 ttttttcttc atttttagtc tccttttccg aatattctct cattatatca gaaaaagtaa
    64081 aaaaaggcaa atttttatat ttttcgtgtc agaaaatata acattgattt ttccttttct
    64141 ttcttgaatt gctattaaaa agtgctataa taatagtata tatagaagaa aagaggacgg
    64201 ggatatgaag aacaaaagaa tatttaaaga cttccaagct tcaaaaatga gtttaaacat
    64261 ttacacaagc cccttgttag cctttgtttt tgtcttcata ggagagtttg tggcttttac
    64321 tttgtatggt attggcttgt tagctctcat cggacttgct agaaattttg gagaggctgg
    64381 tcaaaatctt gcaacctact tgcagacctt gcatcagagc ttgacggata aaacaagtga
    64441 ctttcgttta attttaggat tactggcctt tggttttatt cttaacactg tgttcagatg
    64501 gacaagaaaa gttgagaaaa gacctattcg aaccttggga ttttatagag agaatttcct
    64561 cagcaatctt ctgaaaggat ttagtctagg cttggcactt tttcttctga ccttgttagg
    64621 tttagtggtc ttaggtcaat atcgtttgga atccattcac ttgaatcctt attctcttgc
    64681 ctttgtcgtc tttactatcc cattttggat tttacagggg acagcagaag aagtggtggc
    64741 ccgtgcttgg ctacttcctc aattggcctc aagaaccaat ctaaaactag ctattcttat
    64801 atctagcctg ttctttaccc tgcttcatat gggcaattct ggcctcaccc ctctatctct
    64861 agtaaatctc tttttattcg gagttgccat ggctctttat cttctcaaaa ctgatacagt
    64921 ttggggtgtt gcaggtattc atggtgcttg gaattttgct cagggtaatc tctttgggat
    64981 tttagttagt ggtcaaccgt caggaacgtc tctgatgacc tttttaccac aaggcaatca
    65041 agattggcta tcaggtggtt cttttggcat agaaggttcc attatgacaa gtctggtatt
    65101 actactgctg attgtctatc ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact
    65161 tcggtccgtc cttttcttcg tgaaaatact ataagtatgc taaaatagga atagcacatg
    65221 gagagaggat tcttatgatc aatcacatta cagataatca atttaaacta gtatcaaaat
    65281 atcaaccatc aggagatcaa ccccaagcta tcgagcagtt ggtggataac attgaggggg
    65341 gagaaaaagc tcagattctg atgggggcga ctggaacagg gaagacctat actatgagtc
    65401 aggtcatttc taaagtcaat aaaccaactc tggttattgc ccacaataaa actctggctg
    65461 gtcagctcta tggggagttt aaggaatttt tccctgaaaa tgcagttgag tatttcgtat
    65521 cctactatga ttattaccag ccagaggcct atgtcccttc tagcgatacc tatattgaga
    65581 aggatagttc tgtcaatgac gagattgaca agcttcgcca ctcagctacc tcagcccttt
    65641 tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg tatctatggt ttgggttcgc
    65701 ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg tctagagatt tctcgtgata
    65761 aactcttgaa tgacttggtc gatattcagt ttgaacgtaa tgatattgat ttccaacgcg
    65821 gaagatttcg cgttcgtggg gatgtggtag agattttccc agcttcccga gatgaacatg
    65881 cctttcgagt agaatttttt ggagacgaaa ttgaccgtat ccgtgaggtt gaggctctga
    65941 caggtcaggt attgggagag gtggatcatt tggcgatttt cccagctact cactttgtga
    66001 ccaatgacga ccatatggaa gttgccgttg ccaagattca agcagaatta gaagagcagt
    66061 tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca gcgtttgaaa cagcggacag
    66121 agtatgatat cgaaatgttg cgtgagatgg gctataccaa tggggttgaa aattattctc
    66181 gccacatgga tggacggagc gaaggagagc ctccttatac gcttctcgac ttcttcccag
    66241 atgatttctt gattatgatt gacgagagtc atatgaccat agggcaaatc aagggcatgt
    66301 acaatggaga ccgttcgcgt aaggaaatgc tagtaaatta tggtttccgt ttaccgtctg
    66361 ccttggacaa tcgtcctctc cgtcgtgagg agtttgaaag ccatgtgcat cagattgttt
    66421 acgtatcagc gacacctggt gactatgaaa atgaacagac tgagacggtg attgagcaaa
    66481 tcattcgacc gacagggctt ttggatcctg aggtggaagt ccgtccgact atgggacaga
    66541 ttgatgatct cttaggtgaa atcaatgccc gtgttgaaaa gaatgaacga acctttatca
    66601 ccaccttgac caagaaaatg gcagaggact tgaccgacta tttcaaggaa atgggcatca
    66661 aggtcaagta catgcactcg gatatcaaga ccttggaacg gacggagatt atccgtgatc
    66721 tccgcttggg tgtctttgat gtcttggttg gaatcaatct ccttcgtgaa gggattgacg
    66781 ttcctgaggt tagcttggtt gccattctcg atgctgacaa ggaaggtttc cttcgtaacg
    66841 agcgtggact catccagacc attgggcgtg ccgcccgtaa cagtgaaggt catgtcatca
    66901 tgtatgcaga tacggttacc cagtctatgc aacgtgctat cgatgaaact gcccgccgtc
    66961 ggaaaattca gatggcctat aatgaagagc atggtatcgt accacagaca atcaagaaag
    67021 aaatccgtga cctgattgcc gtgaccaagg cagttgctaa ggaagaggac aaggaagtcg
    67081 acatcaatag cctcaacaaa caagagcgca aagaactcgt caagaaacta gaaaaacaaa
    67141 tgcaagaagc cgtcgaagtg cttgactttg aactggcggc tcagatccgt gatatgatgt
    67201 tggaagtcaa ggccttggat taggggaata gtatgattta tttaagaaag ttaaagaaag
    67261 aagatttgat gtctttatgg gaaatggctt attcacagct taatccagtt tggaaacagt
    67321 atgatgctcc ctattatgat gattatcagt atttttcaaa ttttaaagaa ttcgaactac
    67381 aaaaatcaga atccatttta agcaactcaa atcgccttgg tatttttgtt gatgataaac
    67441 tagttgggac tgtttcgcgt tattgggtat gtaaagaaac aagatggatg gaattgggaa
    67501 ttggtattta tgataaaaaa ttctggaaca ctggtattgg gaaagttgct atgttgcagt
    67561 ggatagatag gacgtttcag gattacttgg agttggagca tctgggtttg acaacttggt
    67621 cagggaatct tggtatgatg aaacttgctg aaaaattaag aatgaaaaaa gaagctcata
    67681 ttccaaaagt tcgttattat caaggtaaat attttgatag tattaaatat ggtattttga
    67741 gagaagactg ggagaaaata aatgacggtt attatcaaat caatggaaac tcctgaagag
    67801 atagaaggta aatccctcgt tcactggcaa acgtggagag aggcttatga tgaccttttg
    67861 cctgcagaat ttcaggagac aatgacatta gaaagatgtc gattctttag tcaaaagtat
    67921 ccagaaaata cattgattgc gataggtgat ctgaaggtag ttggttttat cagttatggt
    67981 aactttcgtg atgatactat tcaagctggt ggaattattg ctttatatgt tttaaaagac
    68041 tattacggaa aaggcatagc acaaaagtta atgaaagcag ctttgactgc tcttaatcat
    68101 ttttctgaaa ttttcttatg ggtattgaaa gataacaagc gcgccattgc tttctatcaa
    68161 aaaatgggtt ttacttttga tggacaagaa aaaatacttg aacttggaaa gcctataaag
    68221 gaaaaacgaa tggtgttcta ttctaaataa ttttaaaaaa gtaaaagata atatctctgg
    68281 tagtaagtct gaaaatttaa taaattagaa agcgagtaaa tttatgtccc gttcccaatt
    68341 aacaatttta acaaatatct gtctgattga agacctcgaa acgcagcgcg tggtgatgca
    68401 gtatcgcgcc cctgaaaaca atcgctggtc tggttatgcc tttcctggag gtcatgtaga
    68461 aaatgatgag gcttttgcgg agtctgtcat tcgtgaaatc tacgaagaaa cagggttgac
    68521 tatccaaaat cctcaacttg tcggcattaa aaattggcca ctagatacag gtgggcgcta
    68581 tattgtcatt tgttataagg cgactgagtt ctctggtacc cttcaatctt cagaagaggg
    68641 agaagtttct tgggtgcaaa aagaccagat tccaaactta aatctggcct atgatatgct
    68701 accattgatg gaaatgatgg aagctcccga caagtcagag tttttctacc ctcgccgtac
    68761 agaagacgat tgggaaaaga aaatcttcta gtcttttact aaataaccta gctgatccaa
    68821 ggcctcctcg atatagtgga ggtcttgttg tgtttcggct tcgactaggt ggtaatggat
    68881 gccatctgtc aattcagata gaggtctaaa gtcagaatgc tcgacttgtt ctagaaaatg
    68941 ttgcacatct ctgcgacaag acagtttaag caaggtttca atttctccat aaacgggatg
    69001 gtcaatcaag gtattctgga catgcccacc attatcgaca atagcaagga gttcctgacc
    69061 gatttcttca acttcatgtt tcactttgaa aagtttgtga acataaggat tggtatcaat
    69121 ttgcttatag atgtagccac gattggtgga taggatagga gcgccatcgg ctctcaaaat
    69181 tgcaatgtcc tgcacaatga cctgacgtgt gacatgaaaa tgttccgcca aactttggcc
    69241 attaagggct ttaggagctt ctttcaagag ttggagcagg gcttgtttgc gatcttttgt
    69301 catagctttt ccttttaacg gcgttttcga agcactttat agacagctag tgctaatgta
    69361 tagtctacca tactatggat aattgtgcca aatccaacta gtacaaatag aacatagaac
    69421 atgttttcta cattggtacc cgaagttgcg taaaaaagga cacaggctaa tacttcagca
    69481 agggcatgaa caacagccaa aacaaaattg aaaacccagg aagattttgg tttatctagg
    69541 gtatcgggga atttttgtag gtaaagagct cctaaagcac caaaagatat atgggaaaaa
    69601 gcccgaaaaa cgataaccat gggatagcca gccatcaaaa atccaaaact agaggctagg
    69661 atgacaaaaa ctgccatcaa gggcgacaag aacatggcta taaaaatagc gatgtggctc
    69721 cccaaagtat aggaagcagg tggaatgaca atcttgaaag gcataacaat tggaatcaaa
    69781 atcgcaatag ccgttaaaag ggctgtcatt gtcataaatt gtgtcttttt ccgtgtattc
    69841 acaagaatct cctttttaac tgcatataca ctagtatggt acaataaacc agacaataaa
    69901 gcaagaattt acttgggttt atagatcatt ttttagttaa aagttatagt agattgaaac
    69961 t
//
LOCUS       DAVBOH010000003        68088 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOH010000003 DAVBOH010000000
VERSION     DAVBOH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.003"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ873_000148"
     CDS             <1..116
                     /locus_tag="VQ873_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3106491.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ873_000149"
     CDS             135..1652
                     /locus_tag="VQ873_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3106492.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ873_000150"
     CDS             1777..3105
                     /locus_tag="VQ873_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3106493.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ873_000151"
     CDS             3358..4224
                     /locus_tag="VQ873_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3106494.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ873_000152"
     CDS             4240..5079
                     /locus_tag="VQ873_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3106495.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ873_000153"
     CDS             5351..5803
                     /locus_tag="VQ873_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3106496.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ873_000154"
     CDS             5900..6244
                     /locus_tag="VQ873_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106497.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ873_000155"
     CDS             6528..7172
                     /locus_tag="VQ873_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3106498.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ873_000156"
     CDS             7341..8258
                     /locus_tag="VQ873_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3106499.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ873_000157"
     CDS             8276..9160
                     /locus_tag="VQ873_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3106500.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ873_000158"
     CDS             complement(9176..10027)
                     /locus_tag="VQ873_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3106501.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ873_000159"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ873_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3106502.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ873_000160"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ873_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3106503.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ873_000161"
     CDS             13086..14129
                     /locus_tag="VQ873_000161"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3106504.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ873_000162"
     CDS             14213..15586
                     /locus_tag="VQ873_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3106505.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ873_000163"
     CDS             15573..16184
                     /locus_tag="VQ873_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3106506.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ873_000164"
     CDS             16275..16979
                     /locus_tag="VQ873_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3106507.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ873_000165"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ873_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3106508.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ873_000166"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ873_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3106509.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ873_000167"
     CDS             19852..20523
                     /locus_tag="VQ873_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3106510.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ873_000168"
     CDS             20533..21072
                     /locus_tag="VQ873_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3106511.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ873_000169"
     CDS             21072..21335
                     /locus_tag="VQ873_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3106512.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ873_000170"
     CDS             21332..22117
                     /locus_tag="VQ873_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3106513.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ873_000171"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ873_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3106514.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ873_000172"
     CDS             23262..26054
                     /locus_tag="VQ873_000172"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3106515.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ873_000173"
     CDS             26457..26837
                     /locus_tag="VQ873_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106516.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ873_000174"
     CDS             27031..27321
                     /locus_tag="VQ873_000174"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106517.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ873_000175"
     CDS             27372..28064
                     /locus_tag="VQ873_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3106518.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ873_000176"
     CDS             28117..30528
                     /locus_tag="VQ873_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3106519.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ873_000177"
     CDS             30778..31479
                     /locus_tag="VQ873_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106520.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ873_000178"
     CDS             31481..34189
                     /locus_tag="VQ873_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3106521.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ873_000179"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ873_000179"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3106522.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ873_000180"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ873_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3106523.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ873_000181"
     CDS             complement(35860..36708)
                     /locus_tag="VQ873_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3106524.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ873_000182"
     CDS             complement(36705..37427)
                     /locus_tag="VQ873_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3106525.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ873_000183"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ873_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3106526.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ873_000184"
     CDS             complement(39733..40362)
                     /locus_tag="VQ873_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3106527.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ873_000185"
     CDS             41358..43580
                     /locus_tag="VQ873_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3106528.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ873_000186"
     CDS             43610..44053
                     /locus_tag="VQ873_000186"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3106529.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ873_000187"
     CDS             complement(44320..44505)
                     /locus_tag="VQ873_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106530.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ873_000188"
     CDS             complement(44524..44937)
                     /locus_tag="VQ873_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106531.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ873_000189"
     CDS             complement(45068..45715)
                     /locus_tag="VQ873_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3106532.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ873_000190"
     CDS             complement(45741..45932)
                     /locus_tag="VQ873_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106533.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ873_000191"
     CDS             complement(45913..46563)
                     /locus_tag="VQ873_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3106534.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ873_000192"
     CDS             46675..47517
                     /locus_tag="VQ873_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3106535.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ873_000193"
     CDS             47593..48030
                     /locus_tag="VQ873_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3106536.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ873_000194"
     CDS             48098..48400
                     /locus_tag="VQ873_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106537.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ873_000195"
     CDS             complement(48491..49564)
                     /locus_tag="VQ873_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3106538.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ873_000196"
     CDS             49720..50397
                     /locus_tag="VQ873_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106539.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ873_000197"
     CDS             50390..51364
                     /locus_tag="VQ873_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3106540.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ873_000198"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ873_000198"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3106541.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ873_000199"
     CDS             complement(53414..53737)
                     /locus_tag="VQ873_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3106542.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ873_000200"
     CDS             54596..55225
                     /locus_tag="VQ873_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3106543.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ873_000201"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ873_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3106544.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ873_000202"
     CDS             56451..57065
                     /locus_tag="VQ873_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3106545.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ873_000203"
     CDS             complement(57358..58107)
                     /locus_tag="VQ873_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3106546.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ873_000204"
     CDS             58240..60576
                     /locus_tag="VQ873_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3106547.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ873_000205"
     CDS             61105..62568
                     /locus_tag="VQ873_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3106548.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ873_000206"
     CDS             62561..62989
                     /locus_tag="VQ873_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3106549.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ873_000207"
     CDS             62967..63416
                     /locus_tag="VQ873_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3106550.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ873_000208"
     CDS             63444..63755
                     /locus_tag="VQ873_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3106551.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ873_000209"
     CDS             63781..64866
                     /locus_tag="VQ873_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3106552.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ873_000210"
     CDS             64877..65572
                     /locus_tag="VQ873_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3106553.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ873_000211"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ873_000211"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3106554.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68088
                     /locus_tag="VQ873_000212"
     CDS             67952..>68088
                     /locus_tag="VQ873_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3106555.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YG"
BASE COUNT        20141 a        12448 c        15283 g        20216 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa tccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttctgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgttggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca agatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccagt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatgg
//
LOCUS       DAVBOH010000004        67910 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOH010000004 DAVBOH010000000
VERSION     DAVBOH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.004"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ873_000213"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ873_000213"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ873_000214"
     CDS             1248..1532
                     /locus_tag="VQ873_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106556.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ873_000215"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ873_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ873_000216"
     CDS             1859..2077
                     /locus_tag="VQ873_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106557.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ873_000217"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ873_000217"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3106558.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ873_000218"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ873_000218"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3106559.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(6376..7221)
                     /locus_tag="VQ873_000219"
     CDS             complement(6376..7221)
                     /locus_tag="VQ873_000219"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3106560.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7477..8345
                     /locus_tag="VQ873_000220"
                     /pseudo
     CDS             7477..8345
                     /locus_tag="VQ873_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8646..10535)
                     /locus_tag="VQ873_000221"
     CDS             complement(8646..10535)
                     /locus_tag="VQ873_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3106561.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10673..12238
                     /locus_tag="VQ873_000222"
     CDS             10673..12238
                     /locus_tag="VQ873_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3106562.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12238..12978
                     /locus_tag="VQ873_000223"
     CDS             12238..12978
                     /locus_tag="VQ873_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3106563.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13087..13302)
                     /locus_tag="VQ873_000224"
     CDS             complement(13087..13302)
                     /locus_tag="VQ873_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106564.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ873_000225"
     CDS             complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ873_000225"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3106565.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15473..15829)
                     /locus_tag="VQ873_000226"
     CDS             complement(15473..15829)
                     /locus_tag="VQ873_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3106566.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(16067..16303)
                     /locus_tag="VQ873_000227"
     CDS             complement(16067..16303)
                     /locus_tag="VQ873_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106567.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ873_000228"
     CDS             complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ873_000228"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3106568.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ873_000229"
     CDS             complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ873_000229"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3106569.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17967..19667)
                     /locus_tag="VQ873_000230"
     CDS             complement(17967..19667)
                     /locus_tag="VQ873_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3106570.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(19868..21535)
                     /locus_tag="VQ873_000231"
     CDS             complement(19868..21535)
                     /locus_tag="VQ873_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3106571.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21538..21903)
                     /locus_tag="VQ873_000232"
     CDS             complement(21538..21903)
                     /locus_tag="VQ873_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3106572.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(22060..22248)
                     /locus_tag="VQ873_000233"
     CDS             complement(22060..22248)
                     /locus_tag="VQ873_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3106573.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22367..22849)
                     /locus_tag="VQ873_000234"
                     /pseudo
     CDS             complement(22367..22849)
                     /locus_tag="VQ873_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            complement(23118..24662)
                     /locus_tag="VQ873_000235"
     CDS             complement(23118..24662)
                     /locus_tag="VQ873_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3106574.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            24875..25177
                     /gene="gatC"
                     /locus_tag="VQ873_000236"
     CDS             24875..25177
                     /gene="gatC"
                     /locus_tag="VQ873_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3106575.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            25177..26643
                     /gene="gatA"
                     /locus_tag="VQ873_000237"
     CDS             25177..26643
                     /gene="gatA"
                     /locus_tag="VQ873_000237"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3106576.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            26643..28085
                     /gene="gatB"
                     /locus_tag="VQ873_000238"
     CDS             26643..28085
                     /gene="gatB"
                     /locus_tag="VQ873_000238"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3106577.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28209..29252
                     /locus_tag="VQ873_000239"
     CDS             28209..29252
                     /locus_tag="VQ873_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3106578.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            29630..30190
                     /gene="efp"
                     /locus_tag="VQ873_000240"
     CDS             29630..30190
                     /gene="efp"
                     /locus_tag="VQ873_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3106579.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30212..30601
                     /locus_tag="VQ873_000241"
     CDS             30212..30601
                     /locus_tag="VQ873_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3106580.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30594..31016
                     /gene="nusB"
                     /locus_tag="VQ873_000242"
     CDS             30594..31016
                     /gene="nusB"
                     /locus_tag="VQ873_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3106581.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31066..31302)
                     /locus_tag="VQ873_000243"
     CDS             complement(31066..31302)
                     /locus_tag="VQ873_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3106582.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31315..31788)
                     /locus_tag="VQ873_000244"
     CDS             complement(31315..31788)
                     /locus_tag="VQ873_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106583.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ873_000245"
     CDS             complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ873_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3106584.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32150..32917)
                     /locus_tag="VQ873_000246"
     CDS             complement(32150..32917)
                     /locus_tag="VQ873_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3106585.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(32914..33780)
                     /locus_tag="VQ873_000247"
     CDS             complement(32914..33780)
                     /locus_tag="VQ873_000247"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3106586.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ873_000248"
     CDS             complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ873_000248"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3106587.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ873_000249"
     CDS             complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ873_000249"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3106588.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(35615..36100)
                     /locus_tag="VQ873_000250"
     CDS             complement(35615..36100)
                     /locus_tag="VQ873_000250"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3106589.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ873_000251"
     CDS             complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ873_000251"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3106590.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ873_000252"
     CDS             complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ873_000252"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3106591.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ873_000253"
     CDS             complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ873_000253"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3106592.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ873_000254"
     CDS             complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ873_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3106593.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(40131..40355)
                     /locus_tag="VQ873_000255"
     CDS             complement(40131..40355)
                     /locus_tag="VQ873_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3106594.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40415..41389)
                     /locus_tag="VQ873_000256"
     CDS             complement(40415..41389)
                     /locus_tag="VQ873_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3106595.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41389..41823)
                     /locus_tag="VQ873_000257"
     CDS             complement(41389..41823)
                     /locus_tag="VQ873_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3106596.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(41917..42702)
                     /locus_tag="VQ873_000258"
     CDS             complement(41917..42702)
                     /locus_tag="VQ873_000258"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3106597.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43027..44391
                     /locus_tag="VQ873_000259"
     CDS             43027..44391
                     /locus_tag="VQ873_000259"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3106598.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            44394..44765
                     /locus_tag="VQ873_000260"
     CDS             44394..44765
                     /locus_tag="VQ873_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3106599.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            44979..46253
                     /gene="serS"
                     /locus_tag="VQ873_000261"
     CDS             44979..46253
                     /gene="serS"
                     /locus_tag="VQ873_000261"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3106600.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46278..47177)
                     /locus_tag="VQ873_000262"
     CDS             complement(46278..47177)
                     /locus_tag="VQ873_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3106601.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47287..47835)
                     /locus_tag="VQ873_000263"
     CDS             complement(47287..47835)
                     /locus_tag="VQ873_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3106602.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48053..49375)
                     /locus_tag="VQ873_000264"
     CDS             complement(48053..49375)
                     /locus_tag="VQ873_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3106603.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(49466..49554)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(49718..52054)
                     /locus_tag="VQ873_000265"
     CDS             complement(49718..52054)
                     /locus_tag="VQ873_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3106604.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52158..52706)
                     /locus_tag="VQ873_000266"
     CDS             complement(52158..52706)
                     /locus_tag="VQ873_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3106605.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ873_000267"
     CDS             complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ873_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3106606.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53092..53964
                     /locus_tag="VQ873_000268"
     CDS             53092..53964
                     /locus_tag="VQ873_000268"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3106607.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            53976..54590
                     /gene="lepB"
                     /locus_tag="VQ873_000269"
     CDS             53976..54590
                     /gene="lepB"
                     /locus_tag="VQ873_000269"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3106608.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            54718..57084
                     /locus_tag="VQ873_000270"
     CDS             54718..57084
                     /locus_tag="VQ873_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3106609.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(57132..58415)
                     /locus_tag="VQ873_000271"
     CDS             complement(57132..58415)
                     /locus_tag="VQ873_000271"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3106610.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(58576..58968)
                     /locus_tag="VQ873_000272"
     CDS             complement(58576..58968)
                     /locus_tag="VQ873_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3106611.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(59267..59896)
                     /locus_tag="VQ873_000273"
     CDS             complement(59267..59896)
                     /locus_tag="VQ873_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3106612.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(59941..60180)
                     /locus_tag="VQ873_000274"
     CDS             complement(59941..60180)
                     /locus_tag="VQ873_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106613.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(60330..60596)
                     /locus_tag="VQ873_000275"
                     /pseudo
     CDS             complement(60330..60596)
                     /locus_tag="VQ873_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(60621..60932)
                     /locus_tag="VQ873_000276"
     CDS             complement(60621..60932)
                     /locus_tag="VQ873_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3106614.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(60857..61099)
                     /locus_tag="VQ873_000277"
     CDS             complement(60857..61099)
                     /locus_tag="VQ873_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3106615.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(61100..61732)
                     /locus_tag="VQ873_000278"
     CDS             complement(61100..61732)
                     /locus_tag="VQ873_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106616.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(61746..62741)
                     /locus_tag="VQ873_000279"
     CDS             complement(61746..62741)
                     /locus_tag="VQ873_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3106617.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(62738..63436)
                     /locus_tag="VQ873_000280"
     CDS             complement(62738..63436)
                     /locus_tag="VQ873_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3106618.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(63513..64523)
                     /locus_tag="VQ873_000281"
     CDS             complement(63513..64523)
                     /locus_tag="VQ873_000281"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3106619.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(64507..65514)
                     /locus_tag="VQ873_000282"
     CDS             complement(64507..65514)
                     /locus_tag="VQ873_000282"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3106620.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ873_000283"
     CDS             complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ873_000283"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3106621.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ873_000284"
     CDS             complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ873_000284"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3106622.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(67436..67558)
                     /locus_tag="VQ873_000285"
     CDS             complement(67436..67558)
                     /locus_tag="VQ873_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3106623.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        20219 a        15195 c        12694 g        19802 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatgaa
     6241 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgc
     6301 agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc
     6361 ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc
     6421 aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa
     6481 gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa
     6541 caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact
     6601 agctccaaac ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact
     6661 ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag
     6721 agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc
     6781 tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac
     6841 cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca
     6901 atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag
     6961 tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt
     7021 aaaataaatc accataactg ctaaaatagc accaagctga atcacgacat taaacatgga
     7081 cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc
     7141 tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt
     7201 taaaatttca ataagataca tatatttctc cttatattat atttaacgca gttagctact
     7261 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
     7321 cgcttgacga tttccgaaag ggtctaacaa cagctttttg tttcaattgg taatgagttt
     7381 gataacgcat agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc
     7441 aagtagactt gaaatactat atctggaggt actcccatgc tttatgtggg cattgatgtc
     7501 gctaaaaata aacacgatgt tacagccttg aatgttcgag gaaaactgtt cttaaaccac
     7561 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
     7621 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
     7681 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
     7741 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
     7801 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
     7861 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
     7921 ctaaaattca ggatatcctc tcagtcgcac ctcgttctat cggaacaaca tctcctgctc
     7981 gtgaattcga aatcatcgaa atcatcaaac attacaagag gctcattgac aaggcggaaa
     8041 catgtgtcaa tgacttgatg gctgagttca actcggtcat cacgacggtt actgggattg
     8101 ggggtcgttt aggggcggtc attttagccg agattcgaaa tattcatgcc tttgataatc
     8161 ctgctcaatt acaagctttc gctggactgg attcttctat ttatcagtca ggtcagattg
     8221 atttagctgg aagaatgatc aaacggggtt cccctcatct gcggtgggca ctcatacaag
     8281 ctgccaaagc atgcgctcgc ttttcacctg cttttaaggc ctatcttaag actaagttag
     8341 aataaggaaa acattacaat gtagccatca tccaccttgc aaaaaaactt atccgaaccc
     8401 tgttttatat cctaaaaaag agctgccatt tgacgaacaa aaagtgatgt aatttctgaa
     8461 attaacacag gattaccttt gaaaaaatgg actttttcaa gggctttttg ccgtgctcta
     8521 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
     8581 tcttatagtt tgtctttctt ctatcttcca ttatatcata ctttttcagt ctatggtagc
     8641 tctctttaaa aggctccgat actgccgcca cctccgcctc cagagaagcc accgccagaa
     8701 cttccacttc cagaagatac ggagtaggta cttgctgtat ttgcgacact agcataatgg
     8761 ctcatttgcg cgcttgaatg ataaaacata ctgtgccagc cataagctac atagagattg
     8821 atatctggat tttcaacttg aatctgatga accttcatca aatgactaac cttgtccgca
     8881 tagccaaata aggttgcata gaccaagaga cgattccaaa caacaatact ttccaattca
     8941 gccttatcca gtcgtgcaat ctcacgtaac atattttcaa aactggtcca gagatagtag
     9001 acctcagctc ccgcttcatt tagaacacca tcacgattat ctagtcgaag cttccaataa
     9061 tagaaaacag acaaaactaa ccctagaaaa ccaagtattg gcaaagggag gtaaagatag
     9121 ccatgaacgt ctaaactgta caagaacaaa ccaaatccga taaatagggg caagatagtc
     9181 aagacaccca tacccacttg caaagccttt tccaaaccag ttaaaggacg atagtaatct
     9241 gggagccccc agaaggaaac tcgttttctc actccttctt gcatctggtt caatacctct
     9301 tcaaaagaag atttgagttg aagccctctt gcttgaatcc gtttttcatc agaaactttg
     9361 gctctacgat aaagactatc agataccttg taatccgcaa acaaattgga aagagtttct
     9421 tcttttttac ctgaaaaagc tagatttagg cagtctttct caaagcttga caaaccatct
     9481 tcttttacta gcctcaaacc aactgcatct ccttctgaaa tgatagagac attcccacgg
     9541 tctatcacat ctagcaaggt agcttgaata agttgatcaa aggtgaattt tccagctccc
     9601 ttgaccaagg gactcacttc ctccaaggag gtcgagtaga ctgcttctga taaaaccata
     9661 ggctctaatt ccattggggg ttcatagaga cgatgatttt tagcatattt gattgaagga
     9721 gcggtctttc ttctatagat aaaatagaaa cagatgctca ataacaagga gatggaaagg
     9781 atcgaaggga agatccaagt aagtagttgt ttactttgat ctttttcttt aacgatcgaa
     9841 tcctctatct tattaaactc ttctaaacga ttccctttca agccctgatc cctagcgcta
     9901 gcaaaatcag ttcgcggcca gtaggcatgc aattcaactc cacgcttagc cggaagattg
     9961 tctaaacgaa tagtataatc aaggttactc ttttcaaccg ttctctctct aaaaagtttc
    10021 cctgtatgga aaaagagttt ctcagccccc ttgtctcccc ttacatgaaa ttcaaacttt
    10081 tcaatagact ctgaactatc tgtcagaggt tgccaattta attcagcgat atcatcataa
    10141 aggaaaagta aattttttaa gttccagacg aggtcaactt caactatgtc gccctcctga
    10201 cctggattat agactctcac agtataacca tccgcttctt ctgttacttc gctagtcaca
    10261 tctgctagtt ctgcaccgtt tttcgcggcc tgaatctttg gatgagggtc aatgtcaaac
    10321 ccgctaggca tcttaccagc acgtccaagt cccacgattt ggcccttaaa gtcctcctca
    10381 aactggtaaa ctatcttctg tctaaactct gccgtattgt ctgcatgaat atacaaatcc
    10441 ccttgataag agtttatctt gaaatcaatg gcaaaaacag agagtggaag aaggcaaaac
    10501 aagcctaaca ccagtaagaa aaaagttttt ttcatcaact aagccccctt tttatctttc
    10561 ttatcattat agcatttttt cgtaagtaaa ggcttactta tgttgaaaaa ttacgcattt
    10621 ttcgataaaa taggagacag ttatttttta atagatcaga ataggagaaa tcatgagaaa
    10681 aatatactta tctattttca caagtctctt gctgatgcta ggacttgtca atgttgctca
    10741 agccgatgaa tatttacgca tcggtatgga agcagcatat gctcccttta actggaccca
    10801 ggatgatgat agcaacggag ctgtcaaaat cgatgggacc aatcagtatg ccaacggata
    10861 cgatgttcaa atcgccaaga aaatcgctaa ggacttaggt aaagaacctt tggttgttaa
    10921 aaccaagtgg gaaggtctag tccctgccct tacttctggt aagattgaca tgattatcgc
    10981 aggtatgagt ccaactgcag aacgcaaaca agaaattacc ttttcgagca gttactatac
    11041 tagcgaacca gttttgcttg tcaaaaaaga ttctgcctac gcaagtgcta aatctttgga
    11101 tgactttaac ggtgcaaaaa tcacttctca acaaggggtc tacctttata acttgattgc
    11161 acaaatccca ggtgctaaaa aagaaacagc catgggagac ttcgctcaaa tgcgacaagc
    11221 tcttgaggct ggtgtcattg atgcttatgt ttctgaacgt ccagaagcac tgactgctga
    11281 agctgcgaac tctaagttca agatgattca agtagaacct ggtttcaaaa ctggggaaga
    11341 agatacagct atcgctattg ggcttcgtaa aaatgacaat cgtattagcc aaatcaatgc
    11401 cagcattgaa accatttcaa aagatgacca agttgccttg atggatcgta tgatcaagga
    11461 acaacctgcc gaagctacaa caactgaaga gactagcagt agtttcttta gccaagttgc
    11521 taaaattctt tctgaaaact ggcaacaact cttgcgtggt gctggtatca ctcttttaat
    11581 ctctatcgtc ggaaccatca taggtctcat tattggactt gccattggtg tcttccgtac
    11641 tgctcctctc tctgaaaaca aagtcattta cggcctacaa aaactagtcg gctgggttct
    11701 caatgtctac attgaaattt tccgtggtac gccaatgatt gttcaatcga tggttatcta
    11761 ctatggaact gcccaagctt tcgggatcaa ccttgaccgt acactggctg ctatcttcat
    11821 cgtttcaatc aataccggtg cctacatgac tgaaatcgtc cgtggtggta tcctagcagt
    11881 tgacaaggga caatttgaag ctgcgactgc tcttggtatg acccataacc agaccatgcg
    11941 taagattgtc ctacctcagg tagtccgtaa catcctacct gcaactggta atgaatttgt
    12001 catcaatatc aaagatacat ctgtattgaa cgttatctct gttgtcgaac tttatttctc
    12061 aggaaatacc gtggcaacac aaacctatca atacttccag acatttacaa tcatcgccgt
    12121 gatttacttt gtcctcacct tcaccgtaac acgtatccta cgctttatcg agcgcagaat
    12181 ggacatggat acctacacta caggtgctaa ccaaatgcaa acggaggatt tgaaataatg
    12241 acacaagcaa tccttgaaat taaacacctc aaaaaatcct atggacaaaa cgaagtgcta
    12301 aaagacattt cactcactgt ccacaaggga gaggtcatct ctatcatcgg aagctctgga
    12361 agcggaaaat cgaccttcct acgctccatt aacctacttg aaacaccaac tgatggacaa
    12421 atcctttatc atggacaaaa cgtcctcgaa aaaggctatg acctcacgca ataccgtgaa
    12481 aagttgggga tggttttcca atcctttaac ctctttgaaa atctcaatgt tcttgaaaac
    12541 acaatcgtcg ctcagacaac tgtcctaaaa cgcgaacgca cagaagctga aaagattgcc
    12601 aaagaaaacc tggaaaaggt cggcatggga gaacgctact ggcaagccaa accaaaacaa
    12661 ctctcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg ccctctccat gaatccggac
    12721 gctattctct ttgatgaacc aacatcagct ctcgatccag aaatggttgg agaagtcctc
    12781 aaaatcatgc aggacctggc tcaggaaggc ttgaccatga ttgtcgtaac ccatgaaatg
    12841 gaatttgccc gtgatgtctc tcaccgtgtt atctttatgg ataagggcgt gatcgctgaa
    12901 gaaggtaaac cagaagacct cttcaccaat cctaaagaag accgaacaaa agagttcctt
    12961 caacgctatc tcaaataaaa agaaaaggct gcatcaaccg tgcagtcttt ttgctgtcct
    13021 caaaatgaaa aggcagattc tctatctcta ctacttgaag gtcaagaatc cgccgttatc
    13081 caaagattaa tcttcaaatt tttcataatt tttttcatag aaatcaatta ggcctagggc
    13141 tgtttcaaat gaaatatttt ttacttttgc acgaccctgc gccagagcaa tgatagacat
    13201 ttcacgcgca ttcgtttctt tagagatacg gtagcctgtg attttcttat cacgaaccca
    13261 gccaacaact gattctactt tttcaaagtt tgacttagcc atgtttttct cctattttct
    13321 tctttataat atttaattgt atacgttttt actacttttg tcaataaaaa aaacatatat
    13381 tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga taatatatag
    13441 gttttgctag cctctacacc ataaatattt gctaataaaa atactgtatt attaccctct
    13501 taaggtgcga aattattcaa gttcttaaaa aatgcttctc tatttccgta agatagctta
    13561 tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact
    13621 agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat
    13681 gtccttaaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga
    13741 ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa ttacttatat
    13801 atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat
    13861 gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt
    13921 tgcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact
    13981 atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa
    14041 gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt
    14101 cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt
    14161 ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata
    14221 agctggatca aaaccttcca ttctacgaat caaacctgca taatcatgct tatctgctaa
    14281 agcgatccca attaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg
    14341 tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg
    14401 ttgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc
    14461 catttctggc atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt
    14521 ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggttc
    14581 tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc
    14641 gacacctacc aaagttttaa tatgttgacg agttgcttca taggtcaact gacctacctt
    14701 ttgcacagca atcccatcag caaatttatc aatttccttg agtttgactg gacctccagc
    14761 ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc
    14821 tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg
    14881 aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc
    14941 aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt
    15001 ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag
    15061 tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt
    15121 agtaatgggc ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc
    15181 ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag
    15241 ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc
    15301 ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg
    15361 agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa
    15421 catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat
    15481 ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt
    15541 taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt
    15601 cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca
    15661 aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt
    15721 gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat
    15781 cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac
    15841 ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag
    15901 tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg atataaatcg
    15961 ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg
    16021 aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa tgttttttat
    16081 ttctcaaaat ccatttcgct atataacgag cagatttagt cgcatcagct ctctcaaacg
    16141 gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa
    16201 aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat
    16261 tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa
    16321 ttacattata caactagaac caataataac gatgcaattt ttctcataat ctttttcata
    16381 aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg
    16441 tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg
    16501 ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca
    16561 aagtcatttg caaacttacc attttggatg tctgccaaga cagccttcat attttcttta
    16621 acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa
    16681 atagactgac gcattttctt gaatccacct tcgtagatca agtcaacgat caatttcatt
    16741 tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg
    16801 aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa
    16861 tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca
    16921 cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca
    16981 taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct
    17041 ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg
    17101 ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct
    17161 tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc agccaactta
    17221 gtagcttctg ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta
    17281 cctggacgta caccgataat aacgtcacga ccggaatcac gcaagttttg agcatgcgca
    17341 tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta
    17401 acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct attatttatt
    17461 gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg
    17521 cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat agggcttcgc
    17581 tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg tctaccactg
    17641 ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca
    17701 tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa
    17761 tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa
    17821 catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc
    17881 tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagt actcctgaac
    17941 gattttgtag ttttgctgtt aacattctac gcatggaact tcacccccaa catctcatga
    18001 ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca
    18061 attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg
    18121 tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc aggaagggta
    18181 tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt
    18241 ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata
    18301 gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac tacttcctta
    18361 tctgggttag caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa
    18421 ccacctgaag tcactaactg acgctcattt tggtagggat aatactgagc tgtccacatt
    18481 tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt
    18541 tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg aacacgattc
    18601 ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct
    18661 agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc
    18721 ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc
    18781 ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct
    18841 tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt
    18901 gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag
    18961 cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct
    19021 aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca
    19081 ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct
    19141 gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta
    19201 gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg
    19261 taattgtact tagtgattgg catggtaatt cccacgatgt ctgcctcctg aaaggcatcc
    19321 ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc
    19381 atggcatccg caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca
    19441 acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca accttgctca
    19501 tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa
    19561 accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa
    19621 actaggtccg accccgtctt aggagattct aaactgattt tctccattat tcccctttct
    19681 ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt caagataaaa
    19741 gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta
    19801 ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc tcagtccttc
    19861 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    19921 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    19981 cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    20041 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    20101 ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    20161 ctgttgtgac gcttccgcta acaacatcgc taagagcagc tgtcatacgc tcttggtttt
    20221 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    20281 gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    20341 agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt tcaacagcct
    20401 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    20461 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    20521 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    20581 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    20641 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    20701 cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    20761 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    20821 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    20881 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    20941 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    21001 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    21061 ctgcgcgcat gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag
    21121 cagctccacg agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg
    21181 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    21241 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    21301 gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg
    21361 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    21421 ctccatctgg gactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    21481 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta
    21541 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    21601 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    21661 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    21721 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    21781 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    21841 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    21901 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    21961 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    22021 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc
    22081 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    22141 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    22201 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    22261 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    22321 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    22381 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    22441 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    22501 gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca cgagactcgc
    22561 ttacatactt tggaataaaa tacctaaaaa aagccgcata tgaaagtccc tcaaagggga
    22621 gacgataacc tttcagaata ctactgtcaa tctgaacatt cacaatctca ctattcaaag
    22681 tctctagtct tttttccatc aattggaacc attctcacgg aaggtcatca ttaaaaacat
    22741 aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca actttatcca
    22801 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctta
    22861 tttcttttta ttcccatcat attattccca tcatatgttt ctacgtaacc attattttcg
    22921 cctattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac
    22981 attttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt
    23041 gaggcagtta gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc
    23101 caattgttgg tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca
    23161 aaccagcgga gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg
    23221 gctaagatat tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga
    23281 acggtctttt tacccattgg gttcataact acttccgcat tgtactcgct ttccatgcgg
    23341 tgtttaaaga cttcaaactg gagttgacct acagcgccta gcatgtactc acctgtttgg
    23401 taattcttat aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag
    23461 gatttttgct tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt
    23521 ggcagtggtt caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa
    23581 gtaccggtat cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga
    23641 ctctccgcca taaactgggt aacattagat agtttggcac ccttaccagt acgagggaga
    23701 ttgacactca tgccacgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca
    23761 cggtgacgag gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca
    23821 taaggatcca caatttcacc gtctgttttc ttgtgaccat gtggttctgg agcaaacttg
    23881 aggaagattt caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca
    23941 ggcgtcaatt ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa
    24001 agctcaatgt catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca
    24061 tcttctaggc tagcaaaacg ctcatcccct ttgtaaagct ctaaacgttg gttatagagg
    24121 tcatacaagc cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca
    24181 atgcccaaga tttcttccaa ttcttgcaag agatccaaag gctcacgacc gtcacgatcc
    24241 aacttgttca taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc
    24301 tttgtttgag cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc
    24361 atcaaggtac gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc
    24421 acgcgcttgc cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc
    24481 ttctcgatat ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta
    24541 ccagcatcac gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc
    24601 gcgtccgggt gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc
    24661 ataagttctc tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta
    24721 cattggattt taccattcct ttcgacactc cattatatcg gattttagca tttttttcaa
    24781 tttctatttc ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca
    24841 gactaaaaat catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac
    24901 acacgttgcc aatctttcaa aattaagatt ctctgaaaaa gaaactgctg cctttgcgac
    24961 caccttgtct aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt
    25021 cgcacctact acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga
    25081 aggaacagac cgtgatcgct tgtttaaaaa cgtacctgaa caagacaact actatatcaa
    25141 ggtgccagct atcctagacg atggaggaga tgcctaatga cttttaacaa taaaactatt
    25201 gaagagttgc acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca
    25261 acacttgaaa atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag
    25321 gagcaagctc ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc
    25381 ctttcaggaa ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact
    25441 gctgcctcaa aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat
    25501 gcaaaaacca aaggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt
    25561 ggttcaggtg aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt
    25621 cctggtgggt catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca
    25681 cttggttctg atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt
    25741 ctcaaaccaa cctacggaac agtttcacgt ttcggtctca ttgcctttgg tagctcatta
    25801 gaccagattg gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt
    25861 gccagcgaag atgctaaaga ctctacttct gctcctgtcc gcatcgccga ctttacttca
    25921 aaaatcggcc aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa
    25981 ggaattaacc cagaggttaa ggaaaccatt ctaaatgccg ctaaacactt tgaaaaattg
    26041 ggtgctattg tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac
    26101 atcatcgctt catcagaagc ttcatcaaac ttgcaacgct tcgacggtat ccgttacggc
    26161 tatcgcgcag aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggt
    26221 tttggtgaag aagtgaagcg ccgtatcatg ctgggtactt tcagtctttc atcaggttac
    26281 tacgatgcct actataagaa ggctggacag gtccgtacac ttatcattca agatttcgaa
    26341 aaagtcttcg cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac
    26401 ttggattctc tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct
    26461 gtaaacttgg caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct
    26521 gtcggactcc aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct
    26581 gcttttgaag caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac
    26641 taatgaactt tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa
    26701 aaatcttctc acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga
    26761 ttgactggtc tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta
    26821 tcaaggctgc tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga
    26881 actacttcta tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg
    26941 gatataatgg ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg
    27001 aacgtgccca cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt
    27061 atgttgacct caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc
    27121 gttctcctga agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg
    27181 gcatttctga cgttaagatg gaggaaggtt cgatgcgtgt ggatgccaac atctcccttc
    27241 gtccttatgg tcaagagaaa ttcggtacca agactgaatt gaagaacctc aactccttct
    27301 caaacgttcg caaggggctt gaatacgaaa tccaacgtca agctgaaata cttcgctcag
    27361 gtggtcaaat tcgccaagaa acacgccgtt acgatgaagc taacaaaaca accatcctca
    27421 tgcgtgtcaa ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct
    27481 ttgaaatttc tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag
    27541 aacgtcgtgc gcgttatgta tctgaccttg gtttatcaga ctacgatgct aatcagttga
    27601 ctgctaataa agtcacttct gacttctttg aaaaagctgt tgccctaggt ggtgatgcca
    27661 aacaagtctc taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa
    27721 cactggaaca aatcgaattg acaccagaaa acttggttga aatgattacc atcatcgaag
    27781 acggtactat ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg
    27841 gtggcgcgcg tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct
    27901 tgatcccaat catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt
    27961 caggcaaacg taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc
    28021 aagccaaccc acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa
    28081 actagacaga acaaaaccag ccctaaggtt ggttttttct tgacaaatag aaagaaaacg
    28141 tttacaatat tgcgtgtaaa gtttccaaac aagaaaacta aaaatcgcaa caataaggag
    28201 ttatttatat ggctacaatg aaggcagctc gctggcatgc agcgaaagat gttcgtattc
    28261 aagaaataga agttcctgaa gtacttccgc accaagtaaa agttgcagtt aagttcacag
    28321 gaatttgtgg tactgacctc catgaatttt tagatggacc tatctttatc ccaacagatg
    28381 agcacgtcta ttctggtcaa aaagcaccgg taacactggg acatgaattt tctggtgaaa
    28441 tcatagaagt cggaagcgat gttacccgtg ttaaagttgg tgatcgtgtt gctgtggaac
    28501 caattctagc taaaaataac ttagttggtg attataattt ggatccaaac cttaattttg
    28561 tcggtttggc tgcagacggt ggatttgcca aatattgtgt tttagacggt gacttagtac
    28621 atgtcattcc agatagcttg agctatgaac aagctgctct tactgaaccc gctgctgttg
    28681 cagtctatgc tgttcgtcaa tcttctttga aggctggcga tacagctgtt gtctttggtt
    28741 taggcccgat tggtctatta attgtagaag ctcttcgtgc agctggtgct tctaagattt
    28801 atgctgttga actatcacct gaacgtcaag caaaagctga agagttagga gctatcgttg
    28861 tccgtccgga agaaggtgaa acagctgttg aagctattca tcgtttaaca aacggtggtg
    28921 tagatgtttc ttatgaagta acgggtgtgc cagtagtttt aggacaagcc ttagctgccg
    28981 tacataaagc aggtgagtgc atggtggtct ctatctggga acgagaagca aatattaatc
    29041 cgaatgaatt tgcaatccaa gaaaagacac taaaaggaat catcgcttat cgtcatatct
    29101 tccctaaagt attagaattg atggaacaag gctacttctc tgctgaaaaa ttagttacta
    29161 agaaaattaa attggaaaat atcgtcgaag aaggctttat cgaattaact caagataagt
    29221 cacaaattaa aattttggta gaaccagaat aaaaaatcaa tctttttaag acaatactaa
    29281 caggtcggag taaacttact tcggcctttt gaaatataat actcttcgaa aatctcttca
    29341 aaccacgtca gcgtcacatt accgtatata tggttactga cttcgtcagt tctatccaca
    29401 acctcaaaac agtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgatttcc
    29461 attgagtatg agaagaaata tagtggatac tctttaacat taaccactcc acctgactag
    29521 ccaatattct ttttcgctcc taccaactcc caataactat tttggcttta tttccagagt
    29581 attttatggt aaaatgaaga gtaataatat ttgttaaaga ggtaaaaaca tgattgaagc
    29641 aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt
    29701 ggaagctagt caccacaaac caggtaaagg aaacacgatc atgcgtatga aattgcgtga
    29761 tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc
    29821 tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat
    29881 gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa acgaattgct
    29941 ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt
    30001 caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc
    30061 tactgttaca ggttctggta aaccagcaac gatggaaact ggacttgtcg taaacgttcc
    30121 agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc
    30181 tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat
    30241 cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa aggtagaggg
    30301 tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg
    30361 tggcatttat cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga
    30421 gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt
    30481 ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc
    30541 agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta
    30601 gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc
    30661 ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag
    30721 atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa
    30781 aggaagaact agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct
    30841 taacgctcgt ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca
    30901 ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa
    30961 aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag
    31021 aaaaagtgtt tgatagatat caaacacttt tttctttgcc tcccactatc taaaaaaatg
    31081 ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa
    31141 aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa
    31201 aaagaaacca atcagactat aatataataa actaattgga tctctgtgag atagtatcaa
    31261 atggctaatc ccaaagatga tagcagatag gataacatcc aaatagtact tggactaggg
    31321 aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat
    31381 tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaaaaag
    31441 cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat agcgtgccca
    31501 aaaattaccg agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca
    31561 gttccagctc tttttctcaa agataaagag catctttttc ttttttaacc tccaaattaa
    31621 tagaaggaaa cttcccacta atcccattgt taaaataaga gaatagacat cagctcctaa
    31681 ccctaaaatg atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat
    31741 aataagcaaa aatattccaa attgtcttag tttttttgtg tttctcatcg tacttttttg
    31801 aaagattacc ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct
    31861 tgcctcatat agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa
    31921 acagcaagac cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt
    31981 gtacctgtca ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat
    32041 atttcttttt ttgtctattt tatagcccat ctcctcaact ggcaattttt cgacctgaat
    32101 tacatttttc cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc
    32161 taaatcgttg atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca
    32221 gctctgtttg gagttctttt ttgacactct taatcagttc tttactagaa agtcctattt
    32281 cagaaatcac cttatctacc acgtccattt ctaacagttc atgcgaagtg attttcatca
    32341 gttctgctgc ttccatagcg cgagtaccgt ccttccataa aatggaagca aagccttctg
    32401 gactgagaat ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag
    32461 ccagagcccc gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt
    32521 cactcatttc catgagattg cgagcgatag cttccccttg accacgttct tccgctccga
    32581 caccaggata agcacctgct gtattgataa aggtcacaac tggacggcca aatttctcag
    32641 cctgtttcat caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc
    32701 gtttgaggtt gtcttgcaaa ctcttgcctt tttggatacc aaccactgtt acagcttgat
    32761 ctccaagcca accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat
    32821 gtaattggat aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct
    32881 gctcacgcgc ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct
    32941 gactaggcta gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc
    33001 atgttctaat aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt
    33061 ttcaatcaca cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc
    33121 gccttccata gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag
    33181 gtaaaagaga ccaacatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat
    33241 gagactcatg attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg
    33301 caatttttcg acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc
    33361 catagaagcc atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat
    33421 aagagcagtt cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag
    33481 tttcttttgg taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc
    33541 tttgaaggtt cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt
    33601 atagctacag tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt
    33661 acagcctgga cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc
    33721 cctaaccgaa cgattgggat tgattcgaat atacttatct tttttactaa atagagccat
    33781 tgattcccct tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg
    33841 taagaaggtt tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga
    33901 aatgaggtca agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag
    33961 ggcacgttgc attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc
    34021 aatcatacta tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg
    34081 caaaccaact ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa
    34141 gttaaaggct gggttttctg cattgatacg acactcgatg gcatgaccac gtaggacaat
    34201 atcttcttgc ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat
    34261 atcaacacct gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc
    34321 catgaaatag aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc
    34381 atagccaaca aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt
    34441 tccgattgca atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca
    34501 atcccgttca cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat
    34561 gtgccgagct ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt
    34621 ggcctcacta gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg
    34681 aatcccttta ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc
    34741 agcaacaatc aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg
    34801 cacacctgct ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac
    34861 atgaccagat ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga
    34921 attttcactg agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc
    34981 tgatagaact gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac
    35041 tgcttcatct gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac
    35101 cgtcgcaatc cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt
    35161 ggcaattaaa atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg
    35221 ataccactgg ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg
    35281 ccacgacgtt ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc
    35341 ttgaacttaa ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt
    35401 gataactcca acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata
    35461 actgggtatt gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata
    35521 gcaacaatgg tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg
    35581 tggggaagag cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac
    35641 caaactcaac catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag
    35701 ctgggatttc attcatgact ttcatggctt cgataattac caatgtttga ccttttttga
    35761 cactatcacc aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc
    35821 caacaagtgg actctctaca agatttccct cactagccac acttgcttca gctggagctg
    35881 gaacttcttc tgctacagtc tctgctggag cagatgtagg agctactgga ttcggtgttg
    35941 ctagaacggg tgctggagcg acttgagttg caacttcagg cacaggtctc gcttcattct
    36001 tgctaaactg caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt
    36061 caaattgagt catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg
    36121 tttgaaagca agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg
    36181 aatttctttc tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc
    36241 acttgtccca gctgtcattg gtacaaagtt atgacgcata gcttcgatgg tgacgatagc
    36301 ttctactgca cccgcagccc ccagcaaatg tcctgtaaaa gacttggttg atgatacagg
    36361 tacttcctta ccaagaacag ctacgatagc accactttct cctttttcat tggcaggagt
    36421 tgacgttccg tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa
    36481 ggctagtttg atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta
    36541 ggcatcacaa gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc
    36601 agcgtgttca agactttcta gaaccaacat ccctgaacct tcacccataa caaacccatt
    36661 gcgatcctta tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt
    36721 taaggcttgg aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa
    36781 catcacatct tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga
    36841 tgaagagcag gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac
    36901 attcccagaa gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg
    36961 tcctttttca tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga
    37021 tgcaacgata acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt
    37081 tacagcctct tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc
    37141 tttttttaca aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc
    37201 aaagtcacta tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact
    37261 attccaaaat tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac
    37321 tactcgattt agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc
    37381 aatggcaacc acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc
    37441 aacctgctct gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat
    37501 cttatctgat aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac
    37561 tcgtatattc cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc
    37621 cttagaagca gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat
    37681 attaatgata gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt
    37741 aaaggcacca gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag
    37801 cataagagta tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc
    37861 tgcaatagct tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat
    37921 gggaaccacc ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc
    37981 acgactgttt aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc
    38041 aattccacga ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct
    38101 ttcaaaactt ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc
    38161 ttccacatga gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt
    38221 ccccggtcca atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc
    38281 atagaaacga acgggttcct tgacctgacg cgtcaagagc tgagcaatgt cctctttttg
    38341 catcacagca gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg
    38401 agctagagtt tcagctagtt tctggctagc aggctcaagg agagcggtgt gaaagggacc
    38461 tgacacctta agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg
    38521 atcaactgca accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg
    38581 agtaaccact ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt
    38641 attgagaact gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc
    38701 acgcttagct accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc
    38761 agagtattct ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa
    38821 taaacggtag atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt
    38881 gagtttgtct tcttccgtat cgatgagata acgtaaatca taaccgagca cctgactcgc
    38941 tcgatcaatc gtttctttga caatcggata ctgatcatag aaatcccgtc ccatccctag
    39001 atactgggca ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg
    39061 cccagcgaga ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga
    39121 tttcttcagc tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc
    39181 caccatccac atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa
    39241 agatttctaa atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc
    39301 tagtcaactg atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag
    39361 tatcaatatc ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt
    39421 ttgcaactac aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg
    39481 cagcaccttc accatccgca attcctcctg cagcaataac aggaatagat atagctgtgg
    39541 ctacctgtcg caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc
    39601 cttctgcaat aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag
    39661 gaacaacagg aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat
    39721 ttcctgctcc tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt
    39781 ccacaaaggg agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga
    39841 ttttatcaat attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta
    39901 atcctccagc cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc
    39961 cttggaaaat aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc
    40021 caaccttcct tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac
    40081 ctaaacaaga gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct
    40141 tgctcttcaa cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt
    40201 tggatatcaa aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg
    40261 tccaaatcat caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca
    40321 acgataattt cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag
    40381 tttttttata acaatgtgtt caccacatga ttacctaaat tgtaagaatg agcgtgcccc
    40441 aggtcaagcc tccaccgaag cctgatagaa gaacagtctg gctaccatct aaagggatga
    40501 gaccttgttc tacacactct gaaagtaaaa tcgggatact ggctgcactg gtattgccat
    40561 attccatcat attggctgga agtttggctc ggtcaacacc aatttttcta gccatcttat
    40621 ccaaaatacg gtcattggct tgatgaagta gcagataatc caagtctgtc acctctatag
    40681 gagattcatc aatagtctgc ttgatagact tggctacatc tcgaatggca aaatcaaaga
    40741 ctgtgcgtcc atccatcttc aaaaacgaat ctgcactttc ttgatctgaa aatggagaat
    40801 gcaaacctga atgcccataa gttaaacact cgctgcgact tccatcgcta ttgagactct
    40861 cagctaagaa atgctcttgc tcgctagctt ctaacaagac accaccagca ccatctccaa
    40921 acaacacagc tgttgatcga tccgaccaat cgactgcctt agagagggtt tcactaccaa
    40981 tcaccaagcc tttttgaaag cgaccagaag cgataaactt ttcagcagtt gaaagagcaa
    41041 atacaaatcc actgcaagcc gcggttaagt caaaagcaaa ggctttatta gcgccaatat
    41101 tagcttgaac acgagcagct gtagagggca tcatcgaatc tggagtaatg gtagctagga
    41161 tgataaaatc cagttctttt cctgttattc cagcttttgc catcagtttc ttagcaacct
    41221 ctgtagccaa atcactggta gattctgttc ttgaaatatg cctttgtcgt attcccgttc
    41281 gacttgaaat ccactcatca ttggtatcca taatctgagc caagtcgtga tttgtaacca
    41341 cttgctctgg cacataatga gcaacctgac ttatttttgc aaaagccatt atttcaaatc
    41401 ctccaaaaat tggtaaagat tagtcaagcc tttacccatg acagcaattt cttcctcgct
    41461 catgccatca ataatttttt ctaccatggc cttgtggaag cgtttatgca gtctatgaat
    41521 caagcgaccc ttctttgtca aatgcagatg caccacacga cgatcctgtt ctgaccgaac
    41581 tcgctcaatg tagcccttac gctctaaatt gttcaaactt gtcgtaacag ttccaagagt
    41641 taccatcaac tcttttgaca cttgacttgg agtcacatct ggagccttac cgatgacatc
    41701 aatcgtatgc atttctttga tggagatatc cttaaaacga ctacctctca agttcacttc
    41761 ctcaattaca aggacattgt taaatataga tgttaaatat tcattgattc gttggtagtc
    41821 catttttcat atccctcctt cttcaaaaaa cttttacaat caaaacattt gacagaaaga
    41881 attatatcaa aattcaaaga atgatgcaag tattttttat tttcctgtaa atttaggtct
    41941 tcttctctcc gaatgagctc gcactccttc tttgaaatcc tctgtttgag ctaaggattt
    42001 ctgtaggttc agttctaaag tagcgtaacc ctgccagtct ttaaactggc tctcccaaac
    42061 caacttctta atggcagcat aggaattact tgaagcacgt cttaattttt taagaagctg
    42121 ttctctcgtc ttttcaagtt tttcagcttc agaaacgcgg taaaccaacc cccattctag
    42181 ggctttttct gccgttaaag cctctcctgt catagctaat tgagcagcac gcgtcacacc
    42241 gatactgcgg ctcaagagat gaattccccc tgcatctgga gccaaaccaa caccaacaaa
    42301 ggcttggata aacttagcct tatccgtcgc caaacagaaa tctgccgcaa cagccatatt
    42361 cgctgcggca cctgcaacag caccgtcaac ttccattaaa acaggtttgg ctatttgctt
    42421 gattttataa gaaatcgtat tgaccaactc tgcgattttt gtcaatgatg gaatatcatc
    42481 ctcatccact gcccgcttca tctctaccaa atctccccca actgagaaga cctttccatt
    42541 ggcattgatt aagataaaat gcacagctgg attttcttct gccaaagtca gagcttctaa
    42601 aatctcctca cacatgggaa tatgaaaacc atttgcgacc tcaggacggt tcaaggtaag
    42661 gattgccaag tcctcttcaa gctgataaat aatgtgttcc atcagggctc ctttttattt
    42721 tataagcagt ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcc atctgtaacc
    42781 tcaaaacagt attttgagca gtctgcggct agcttcctag tttgctcttt gattttcatt
    42841 gagtgttaaa ttatttcact gtcaaagtat atctttttta ggagcagaaa gcaagaaaaa
    42901 atcgactgaa agtgtctcag ccgataagaa aggctcgctt taggctagaa agcatcttat
    42961 tttcttcatt gaaaaaagcc tttctttctg ctataatcgt ataaaatact tactttagga
    43021 gttcttatga aagttgttaa atttggaggt agttctcttg cctctgctag tcaattagaa
    43081 aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt ttgtagtcgt ttctgcgcct
    43141 ggtaaacgca atgctgaaga tactaaggtt acggatgccc tgattaaata ctaccgcgac
    43201 tatgttgcgg gtaacgatat tagcaagagc caaagctgga ttatcgaccg ctatgctgct
    43261 atggttagtg aattgggact aaaaccagct gtgctagaaa aaatttctaa aagcattcac
    43321 gccttggcca ctcttcctat tgaagaaaat gaatttctct acgatacttt cctagcagcc
    43381 ggtgaaaata acaatgccaa attgattgct gcctacttta accaaaatgg tatcgatgca
    43441 cgctatatgc accctagaga agctgggatt gtggtcacaa gtgaacctgg tcacgctcgc
    43501 atcattccat caagttatga caagattgaa gaattgacaa acaccaatga agtccttgtc
    43561 attcctggtt tctttggtgt cactaaggaa aatcaaatct gtactttctc acgtggaggt
    43621 tctgatatta caggttctat cattgctgct ggtgtcaaag ctgacctcta tgaaaacttt
    43681 acggacgttg atggtatctt tgcagcccac cctggtatta tccaccaacc acactcgatt
    43741 cctgagttga cctaccgtga aatgcgcgag ttggcctatg caggcttctc agtccttcat
    43801 gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc tggttatcaa gaataccaac
    43861 aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca gtaatgatga atttccagtt
    43921 gtgggaattg ctggtgactc aggctttgtc agcattaaca tgtcgaaata cctcatgaac
    43981 cgtgaggttg gatttggccg caaggttctg caaatcctgg aagaacttaa catcggttgg
    44041 gaacatatgc caacaggtat cgacgatctt tctatcattc tccgttctcg ccaactaact
    44101 cccatcaagg aagaagaaat cctgcgtcag ttggttcaaa aggctaaagt agatcatgca
    44161 gaaatcgaac acgacctttc tatcattatg attgttggtg aaaaaatgaa gagccacatc
    44221 ggagtgactg ctactgcgac acgcgctcta tctgaaaaca aaatcaacat ccagatgatg
    44281 tctcaaggtt ctagtgaagt ttctattatg tttgttgtca ataaagacca agagaaagca
    44341 gcaattaaag ccctctacaa tgcctttttt ggagaaagta aggaagacta agcatggccc
    44401 aatcacttaa caaaacagta ctcctcagta cgacaggcac ttcctacctc tctatcgctg
    44461 ggaaagttgg gaaattcctt gtcggagatc aggctttgga attttaccca gatgtcaatg
    44521 tcgaacaatt tatccagatt ccttggagcc atatcaatca gattggagcc aatgtcactg
    44581 gatgcaaaat cagccgccac ttcgaagtct ttacagacaa aggaaaattc ctctttgctt
    44641 caaaagactc aggtgccatt ctcaaaattg cacgcgacaa attgggcaat gacaaggtcg
    44701 tcaaacttcc gaccctgatt cagacaatta gccaaaaatt taaaaatcta tttgcaaaaa
    44761 aatagaaact ttagtataat catagcaacg gataagtagg ttatcttctt ctttcagaaa
    44821 gtctgcgggt gctgcgagca gataggaggg ataggtgaaa ttctaccgtt agtaacaatt
    44881 acatacacaa tcaagtgcac acctgtgaag ttggatggaa ccgtggccct gccactccaa
    44941 cgttttgtca ggtgtgcttt tttcataaag gagttcttat gttagatatc aaacgtattc
    45001 gtacagattt tgaagctgtc gcagaaaaat tagctacacg tggtgtagat gctgctgtct
    45061 tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag gttgaaactc
    45121 tcaaagcaga acgtaacaca gtttctgctg agattgccca agctaagcgc aacaaggaaa
    45181 atacagatga caagattgct gccatgcaaa atctatctgc tgaggttaaa gccttggatg
    45241 ctgaattggc agaaatcgat gctaaattga cagaatttac aacgactctt ccaaatatcc
    45301 cagctgacag cgttcctgtt ggggctgacg aagacgacaa tgtggaagtt cgccgttggg
    45361 gtactccacg cgagtttgac ttcgaaccta aagctcactg ggatctcggt gaagaccttg
    45421 gtatccttga ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc ttctataaag
    45481 gcctcggtgc tcgtttggaa cgtgctatct acaactttat gttggatgaa catggaaaag
    45541 aaggctatac tgaagtcatc acaccttaca tagtcaacca tgattctatg tttggtactg
    45601 gtcagtatcc aaaatttaag gaagatactt ttgaactcag cgataccaac tttgtcttga
    45661 ttccaactgc tgaagttcct ctggcaaact actaccgtga tgaaatctta gacggcaaag
    45721 atcttccaat ctacttcact gctatgagtc cgtcattccg ttctgaggct ggttctgccg
    45781 gtcgtgatac gcgtggcttg atccgtttgc accaattcca caaggttgaa atggtcaaat
    45841 ttgccaaacc agaagaatct tacgaagaat tggaaaaaat gacagccaac gctgaaaaca
    45901 ttcttcaaaa actcaacctt ccataccgtg tcgttgctct ctctactgga gatatgggct
    45961 tctcagctgc gaagacttac gacttggaag tgtggattcc agcacaaaac aattaccgtg
    46021 aaatctcaag ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa atccgttacc
    46081 gtgatgaagc agatggcaag gtgaaactcc ttcatacctt gaacggttct ggacttgcag
    46141 ttggacgtac agtggctgca attcttgaaa attaccaaaa tgaagatggt tctgtgacca
    46201 tcccagaagc acttcgtcca tacatgggtg gagctgaagt catcaaacca taaaaaataa
    46261 ggtttagcta tttctagcta gacctttttt cgtaaccaaa tcagataagc acctagtaca
    46321 aagaataaaa tagttaggca tataatggtt tcagccaata ccaggtaatc cagaaatgga
    46381 agtttcaaaa ttccctgagc catcttgagc gaggtcgctg tgataatggt tgggaaggtg
    46441 agggctgaga aggctggttg aaaaccttgt tttaaaatgt tgggcagacg agttaaaaca
    46501 aagaaaaaga aggattgaga agccaaaatc atgacaatca agacccaatt cggcaggctg
    46561 gttcctccta ctcgaactag agaagccaag agtagagaga aaggagcaca gtagattcct
    46621 tcttgtccaa gcaaggctag tgggagtgga tgtttcttta aatcgctata aataagggga
    46681 tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg cataggcaat ttcgataata
    46741 cctaccagag gataggtcaa ggcagccact gctatcccca catagagaac cgtccaactt
    46801 ggagtggcat gaaccctccg ccctgaacaa gcaaacttga tggtaaaacc agcaatcaag
    46861 gtcaaatcca agagaaatga aaaccaccaa atcccttgtg ctaccaaagg aagataagag
    46921 aatacgcgaa agacataggt cgataaaatc atcccagcca taggaaaggt tgccattcct
    46981 gacaaaagag ggggcttggt caattcttgc ttggtttctt tccaattaaa gagatgcaga
    47041 attagaaagt aaatccataa aaccaaacca gtcagactaa aaagatggga tagaaccggc
    47101 aacgtatcta aaataagatt tccagctcct gccaaaccta gcaaacaacc tgaaaatact
    47161 aaggggagtt ttttcatcct aacctccaat aatcatgtta gtttcagtat aacataaaag
    47221 cgcttaaatg atgatttaaa aaaacgaagt ccgattattt cagacttcat tttactcaga
    47281 tatgaattag gcataaggtt gcaattctgg attaattggt gtattagcta agttgttggc
    47341 atagttacag aggattgcta ggctgacacc aaaaaccaca tccaaggcat tttgttgagt
    47401 gtagccagct tctaaaaact cagacaaggc ttcatctcct acacgaccct tggtattgat
    47461 aactgccaag gtaaacttag ctagggtatc caatttagga tctgtttcaa ttggagtacg
    47521 attgcgaaga gcttgaatca agtcatcatt catctggatt tgtttgatgg aaaaggctgt
    47581 gtgacctgcg acacagaagg cacaaccatt ggtcacggct gccgtgattt gcaccacttc
    47641 acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat gagacaattt ggtaggcttc
    47701 taaaacagtc ggggcattgg ccaagagacc gattaggttg ggaatatagc cattgttgtc
    47761 tttttctact gtttcaagaa tttctttcac ttctgctggt gctgactcta ctgtatggat
    47821 agtaaatgtt gtcataagat acctcttttc ttattattga cactaatatt attggaaaat
    47881 cttataaaat cctgattcct aagtttatct aagataaagc tttattctct cataagattt
    47941 tcgttgttat attagtttat cacacttcca atcacttgca taatatatat tatatatcag
    48001 gctgataaaa attatttata ggcaaaaaaa tcacacgagc tgtgtgattc cattatttgt
    48061 caaaatactt tttagtttca gcaataacga cttgcgacaa gaccaagagg gcaatcaagt
    48121 ttggcagagc catcaaggcg ttaacgatat ctgcgataat ccagaccata tccaactcga
    48181 taaatcctcc taacaagacc atgagcacaa aaaccacacg gtagagccag ataaagcgaa
    48241 ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt ccaacctaga atcgttgtaa
    48301 aggcaaaaag tacaaggaag atggtcaaga gggcaggccc aaagtgtgaa aagactgttg
    48361 agaaagctga ctgagtcaag gcaaccccat tcaagtcacc actccaaact ccagttacca
    48421 agatggtcaa accagttaga gtacaaatga tgagggtatc aataaaggtt cctgtcatgg
    48481 aaatcaaacc ttgctctact ggttcatttg tcttggcagc tgcagctgca ataggagcag
    48541 aacccagacc agattcgttt gagaacacac cacgcgccac accattttga atagccatcc
    48601 gaacgctagc accagcaaat ccacctaccg cagcaagggg actaaaagct gaggtaaaga
    48661 ctaaagcgat tgtgccaggg atttttccga tattaaagaa aataactata agagttccta
    48721 agatataaat gatggtcata aaaggaacaa cagtagttga aaccttagaa atagacttga
    48781 gtccaccaaa gactgcaatc gctacaaaga cagacaagac gagagctgtg atgactggcg
    48841 aaatcgtcgt tgtattttgg atagattctg taatcgagtt gacttgggtg aaggttccga
    48901 ttcccaagag agcaaccaat actcctgcta ctgcaaacaa aacagcaagt ggtcgccact
    48961 tttctcccat ccctagaagg atatagtgca tgggacctcc cgctactgca ccatggtcgt
    49021 ccttggtgcg gtatttgatg gccaagagtc cttccgcata cttggtagcc attccaaaga
    49081 aagccgccat ccacatccaa aatagagctc ctggtccacc aaccttgata gccgtcgcaa
    49141 ctcctatgat atttcctgtt ccaacagttg atgccaaggc tgtacacaga gctgcaaaac
    49201 tggatacatc accatgtccc ttatcctgga taaaaataag ctgaaaggcc ttgggcagac
    49261 gcaaaacctg caagagtcct agccgcatgg ttaggtaaat ccctgttccg accaataaaa
    49321 tcaagagggg cggtccccaa gcaaaatcat cgattgattt aagcaattct aacatttcct
    49381 tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa gatacatgta ctctggaatg
    49441 cttagataaa tgctaaaaag cggtctatcc tagctctgtc cttttacctg agagtttgag
    49501 cagttgccta ccttgcccct tcggtgcctt tacggtctct ccagagttcc gtccatttac
    49561 agtcatggaa aatcaaacga ttccccactt ctattaaact tcattcggtg ttggtattta
    49621 attgattcta attttacaaa aaatgttggc ttttgtcaat gtgtttatta gtaaaaatta
    49681 gttcaacagt ttttacttta taaagtccag aatactgcta tcctttaaaa gtgacaatag
    49741 tcgcaccact gcctccagca ttttgtgggg catagccgaa actcttgaca tgtttgtttc
    49801 tttgcaagta tttggtaact ccttcacgga tgactcctgt tccgatacca tggatgatat
    49861 caacttgagc catattgtta agcaaggctt ggtcgatgaa ggtatctagc tcattcatgg
    49921 cttcttcata gcgcttgcct cgaagatcca gtctagcttg aggtcctcgc ccagaagttc
    49981 gtttcacaac attgacctgt ttcttcttga ctggtttttc ttgctgggct tgaacaagat
    50041 caaactcttt ctcttccaag gtcatcttaa tcaagccaac ttgggcttcc cagcggccgt
    50101 ccttgagttg actggtcaag gtaccacgct gaccataact gagaaccacg atatcatctc
    50161 ccacctttgg agctcgtttt ttcttggcct tttgaaggac cttgttttta gacaagtcca
    50221 ctttttcagg agccaatttt ttcaacttgg ccttggcttc aatgatttcg tggggcttga
    50281 gttgggattt actgtggaga tttttgagaa tctggtcact ttcacttagg gccatatcca
    50341 caatctcagc agcctgttca cgcgccttgt taagctcggt ttccttttca cgattaagct
    50401 cgttgtagag tttttttagc gcacggttca tcttgagatt ttcttgctcc acctcacgga
    50461 tattgtccaa acgtttgcgg ctttccagcg tctgctcttc taattgctca atgatacgat
    50521 tgacgtcatt gtcctgatcg atctgctgac tggcatctcc tacgataact tcagataggc
    50581 ctagacgttt ggcaatttca aaggcattac ttcggccagg aacaccctgc ataaagcgat
    50641 aggtcgggcg aagagttgca gtatcaaact ccatactggc attttgcaca aaggctgtct
    50701 caataccgta ggccttgagt tctggatagt gggtcgtcgc catggtcttg atttgacgca
    50761 ggcgaaggtc ctccagaata gccatggcaa gggctgctcc ctcttgggga tcagtaccag
    50821 cccccaactc atccaaaagt aagagtgaat gttggttgac cttgccaaga atatccacga
    50881 tattggtcat atggctagag aaggtagaca agctctgctc aatagactgc tcatctccaa
    50941 tatcagcaaa gatttcttca aaaataccaa cacgacttcc cttgtctgct aaaatcggca
    51001 atcctgactg ggccatgacc tgtgtcaagc ccagagtttt gagcatgatg gtcttcccac
    51061 ctgtattggg acctgtaatg acaatagctg ttaaatcttg accaaaatag acatcatttg
    51121 cgacggcatt tttgaccaaa ggatggcaga catggagcag ttgaatctct tgattttctg
    51181 acagctgagg cacgactgct tgtctttctt ggataaatcg aaccttggca cgaatcaagt
    51241 ccagatgacc gataatccaa gcgtcattag caatctcagc cgcatgaggg cggacacgct
    51301 cagaaatttc ttggagaatg cgaagcattt catagcgctc atctgctcgc agactagcaa
    51361 tttcttcgct cagtttgact acctcacgtg gttcgatata gacggtgttt ccactagcag
    51421 aaatatcatg aacgacacct gcaatcttat tgcggtaggt gtttttgact ggtaaaacct
    51481 gacggccatt tctgctagca acaattcctt ccgtcaacat ctgcgctttt tgcttgagta
    51541 agtcttgtaa aacatcgcgc acctgactct cgctatcatg tatttttcga cggattcgcg
    51601 ccaattcttc actggcaaaa ttttcaatga aacccgcatc attaaaggcc tgaagatttc
    51661 cttgtaattg cggaaaatca tgtaatttct caaaccaaag ggctaattct tccaagctga
    51721 cattttccag attggcgtaa aaattttgaa gttctcggct ggcaagaagc acgcgtttca
    51781 agagtaggaa ctcctcgata ttgagatccg ctcccatctc caacctcttg cagactcctg
    51841 caatttcctt agttgagaga atagtaaaat gcggttgctc gacgaaaaga gcctgcattt
    51901 ctttcatctc agcaaaagcc tgtttgattt tatctgcttt ggcagtcgga gccagctgtc
    51961 tcaattgctc caagccctgc tcggtcaaca aatgaggctc aaacaaggcc ttgaccttat
    52021 cgaactctaa tgtttctaat attttcttat tcatctttat ttccttgtct ttgaatgtct
    52081 aggtgtggta gctttttaca ttctgataga ttcgagtcaa atctgtaaac aaagggctag
    52141 gaaaactcct gcccttttta tccgattaaa tttgtcaccc agatttgttt gagccaactg
    52201 gttgttaccg gtatgctctg gatgatgtgt tttgcgacga tactcttttc aagaggattt
    52261 tgtataactg ccatggggat ggtcgccaag attgtcaagg ccatttgcaa gacaaataag
    52321 gtcaccaaca tggacaagat acctgctgaa acttggaaca acttaccacc cagttttttg
    52381 ctaggaatca agtgtaagag aagaccaagt aaacgaccaa tgctatagac aatcccaaat
    52441 acaagcaagt agccgatacc tgcataaaag accttatcca gctgaaagag ttgatccgat
    52501 gggaaaaaga aagtcccctg accttcctgc gaatttgcat aagggagcaa taaatggaat
    52561 tgctctccaa gccccttata aaactggcca gccataaaag ccgatgccat ggctgaaatc
    52621 aggtaataaa cctgtaagag caggcctctc cgatagccga tataaaatcc ccaaaccaag
    52681 accaatagaa gaaggaatga aatcataagg aatcctcaat cttgctctgt tcttgcttac
    52741 aagtcacaag cttgtgacgg agttcttcta gctcttgctc cttatcgtca aattcaatct
    52801 cacggctgag ctgagttgat aaacagttga ctgccaacaa aagagcgatt gtttcatcat
    52861 ctgcgctagg catttgttct ttaattgctt ggtatttttc tgtcgcaacc ttagcgattt
    52921 cctccataaa aaggttgtca tgttcgcttg tcaaggttaa cgattttttc ccgaatgtaa
    52981 atttgaatcg atttagattt gccataaaat tcacctcacg atattatacc aaaattcgct
    53041 aattttgtca gtttttacaa attttactgc ttttgtggta caatagaaac tatggcaagt
    53101 atcacactca caccaagcga aaaggatatt caggcttttc ttgaacacta tcaaaccagt
    53161 ctggctccta gcaagaatcc ctatatccgc tactttttga aactacctca agcaacggtt
    53221 tctatctata cttctggaaa aatcttgctt cagggtgaag gggctgaaaa atacgccagt
    53281 ttctttggct atcaagctgt agagcaaacc agcggacaaa atcttccttt aattgggaca
    53341 gatgaggtgg gaaatggttc ctactttggt gggcttgcag ttgtggctgc ctttgtcaca
    53401 cctgaccagc acgacttttt acgaaaactc ggtgtggggg attctaagac tctgaccgac
    53461 caaaagatcc gtcagattgc tcctattctc aaggaaaaaa ttcagcacca ggcactcctt
    53521 ctctcaccca gcaagtacaa cgaggtcatc ggagaccgct acaacgctgt ttcggttaag
    53581 gttgccctcc ataatcaggc tatctatctc ctccttcaaa aaggtgttca gcctgagaaa
    53641 attgtgattg atgcctttac cagtgctaaa aattatgaca agtacttggc acaagaggcc
    53701 aatcgtttca gcaattctat cagcttagaa gaaaaggctg agggcaaata cttggctgtc
    53761 gcagtttctt ctgtcattgc gcgtgatctc tttctggaaa atcttgaaaa tttgggacga
    53821 gaactgggtt atcagcttcc aagtggagct ggaacggctt ctgacaaggt ggctagccag
    53881 attttgcaag cctatggtat gcagggactc aacttctgcg ctaagctaca ctttaaaaat
    53941 actgaaaaag cgaaaaacgc ttagaaaggt aagttatgaa tttatttaaa aatttcttaa
    54001 aagagtgggg attattcctc ctgattctgt cattactagc tttgagccgt atcttttttt
    54061 ggagcaatgt tcgcgtagaa ggacattcca tggatccgac cctagcggat ggtgaaattc
    54121 tcttcgttgt aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag
    54181 atgggaataa ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg
    54241 aaaatgataa actctacatc aatgacaaag aaacggacga gccttatcta gcagactata
    54301 tcaaacgctt caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa
    54361 ataaaggaac tttctttaga agtatcgctc aaaaagctca agccttcaca gttgatgtca
    54421 actacaacac caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg
    54481 accgcttggt ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag
    54541 gggaagctaa attccgctta tggccaatca cccgtatcgg aacattttaa gaaacctaag
    54601 aggccgagaa tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtaactat
    54661 ctaaacttac cagaacagaa acacctcaac tctcacctat tcatgcaaag gaattttatg
    54721 gaagtttatt tttcaggaac cattgaacgg attatttttg aaaatcccag caatttttat
    54781 cgcatcctcc tcctagaaat cgacgatacg gacgcagagg attttgatga ttttgaaatc
    54841 attgtcacag gaaccatggc tgatgtaatt gagggcgaag actatacttt ttgggggcaa
    54901 attgtccagc actccaagta tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa
    54961 ccaactagta agggcttggt caagtacttt tcaagtagcc atttcaaggg gattggtctc
    55021 aagacagctc agaaaatcgt ggatacctat ggcgaaaata ccattgacga aattttgcaa
    55081 cacccagaaa agttagaagg catcgcagga ttctctgcca aaaatcgcga ggctttcgtc
    55141 tccactctcc gtctcaacta cggaacggag atggttttgt ccaaactagc caactacggc
    55201 attcccaaca aactagcctt tcagattcaa gacttttaca aggaagaaac ccttgatgtg
    55261 gttgaaaatt atccctacca gctggttgag gatatcaagg gtttgggctt tacaattgct
    55321 gaccaactag ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt
    55381 ctagttcaca gtctttttca ggcctgtatg gaaacagggg acacctatgt tgaagcacgg
    55441 gatttgctgg aacaaaccct tactctcctt gagtcttccc gtcccgtgga actagacccc
    55501 agccaagttg cccaagagct ctcctacctg atcgaagaag acaaggttca gcagattgat
    55561 accaagatct ttgacaacag cctctttttc gctgaggaag gtatccgcag tcacttgatt
    55621 cgtatccttg aaaaaggaaa acagaagagc caagatttag aaactattca aaagcatatc
    55681 actactgtcg agcaagagct gggaattgag tatgataaca ttcaaaaaca ggctatctgt
    55741 gatgctatcc agaataaggt ctttatcctg acaggtggac ctggtactgg taagacaact
    55801 gttatcaatg ggatcatcgc tgtttacgcc ctgttagagg gacttgacct caggaagaaa
    55861 agcaatctgc ccattcttct tgctgctcca actggacgag ccgctcgccg catgaatgaa
    55921 ttgacaggtt tgcctagcgc gaccatacac cgccacttgg gaatgacagg tgacgatgat
    55981 accagtcatc tggaagatta cctagatgct gactttatca tcgtggatga attctctatg
    56041 gtagatactt ggctggccaa tcaactcttc tccaatatct cttctaacag taagatcctc
    56101 atcgtaggtg acagtgatca gctaccttct gtcagtcctg gacaggttct agcggatctg
    56161 cttcatattc ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca aagcaaagaa
    56221 tcaaccatcg tcaccctagc tagtcagatt cgacagggca tcttgccagc tgatttcacc
    56281 caaaaaaaag ctgaccgttc ctactttgaa attgctagtg gccatattcc tgccaccatt
    56341 gaaaaaatct taggtgtcgc cctcagaaat ggtattcctg cccgtgatat ccaagttctg
    56401 gctcctatgt accgagggac ggcagggatt gatgctatca atcagctcat gcaagacctg
    56461 ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag
    56521 agagacaagg tcattcattt ggttaacgat gctgaaatca atgtctttaa tggggattta
    56581 ggagctatca cagacctgat tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc
    56641 attgattttg atggtaatga agtctcttac ccccgtaacg aatggtacaa gattcgcttg
    56701 gcctatgcca tgagtattca taagtctcag ggaagtgagt tcccagttgt catcctaccg
    56761 attactagtg ctagccgacg tatgctggag cgaaatctca tctacacagc cattacacgt
    56821 gccaaaagca aactcatctt actaggcgaa ttacaagcct tcgactatgc tacccaacac
    56881 atcggaactg cccgaaaaac ctatctgatt gaacgcttca gtgatctact ggagaatgtt
    56941 gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga acaatcctac
    57001 atcctaaccg aagaaaactg ggaccgcatc ccagccatga ttgggattac agacacagac
    57061 ctcaaagaga tttttggaaa atagtgcatc agaaaaccca ccaattcagg tgggttttct
    57121 gtttattaag attattttac tgttgctgtg cttgtgatca attcaacagc ttttttgata
    57181 gtgatatcat gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc aacttccatg
    57241 ttgtagtctg ctgccaattg ctcaacttct ttttggattt cttcttctga agcatcaaat
    57301 ccttcagctt tggcaactgc ttcgataaca aggttagtct tagtacgtga ctcagcttct
    57361 gcttggtatt ggttgtgaag gtcttcttga gtagttccag tgatttggaa gtacatgtca
    57421 gggttgatcc cttgacgttg caaattccca aggaattcat ttactgaacg gtgaacttct
    57481 tcatggatca tttcttctgg aagttctacg atttcagcat tttctacagc tgtatcaatt
    57541 gctgcacctt caactgcatc tttgtaagct tcttctttag cagcagccaa ttctttgcgg
    57601 tatttttctt tcaagtcagc aagtgtttca acttcttcat caatgtcttt tgcaagttca
    57661 tcgtcaagag ctggaacttc tttagctttt acttcgtgga tagttgtcac gaatttagct
    57721 tctttacctg caaggtcttc tgcttggtag tcttctggga atgttacgat aacatcaacg
    57781 gtttcgccag ctgagtgacc taccaattgg tcttcgaaac cagggatgaa ttgacctgaa
    57841 ccaagtccaa gtgagaagtt ttcacctttt ccgccgtcaa attcaacacc gtcgatagaa
    57901 ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag cagcttcctt gataaccaat
    57961 tcagccaggt tgttgcgttc gcgttcgata cgctcttcaa catcagcgtc agttacttct
    58021 ttttctacat caactgatac ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt
    58081 gtaacgactt cagcagcgat aacccagtct tgaccttttt ccattgaagt tacgtcaatt
    58141 tttggttggg caaccacttc aagaccagct tcttttacag ctgcttcata agcgtttggc
    58201 aaaagagcgt tcataacgtc ttggtaaagt gattcttcac caaatttttt atcgaagata
    58261 ggacgtggaa ggtgaccttt acggaaacct ggaacattaa gagatttctt cactgacttg
    58321 aagacacggt ccaattctgg tttgatttgg tcttgagaga tagtgaaagt caagacacca
    58381 cggtttgttt ctttgttttc aaatgataca gacattctgt catttctcct taaaattttt
    58441 taaatacagt ctattataac attttctata aataaaatct agactaatgc agccaattat
    58501 agacaacaag cctttttcct aactaaaaca ctcataaagt atagacaatt ttagactact
    58561 ttggatatct tttggttagt cattttccaa aactaattta tctaattttt cagttatatt
    58621 tgacttcatc ttctcagtaa catgagtata aacacttaaa atctttgttt cattagtata
    58681 atctacacga tccattatcg ctgttatagg tacttccaat tcagcaagca aacttatatg
    58741 cgaatatcta aaaacatgag cagtcaatac aaaatcatct ttcttaattt cacttttcct
    58801 aaaactgttt ttcaaaaagt aattgaaaca agttatcatt aagggagaac cattatttgt
    58861 aaatatataa tcaccttctt ctaaaagaag atattctttt aaaatttcta acactctatc
    58921 actaatacca attactctat atgaagctaa acttttcgga ctatccaaaa atacttcgtt
    58981 attggacgat tacattatag taaaacgaaa taagaacagg acaaatcgat caggacagtc
    59041 aaatcaattt ctaacaatgt tttagaagta gaggtgtact attatagttt caatctacta
    59101 tacaagacga aattgaagaa atctttccat tataaaacgc atattatcaa ggtttttaaa
    59161 cacctaataa tatgcgtttt ttcctatttt aaagactttt atccacctat tatacaaagt
    59221 taagtatcca tcacagttta caattagcct tcattaccta acccattcac catccttcaa
    59281 gagagtaacc tttaagaacc gaataaataa atggcaaatt tcgttcattt aatttaactg
    59341 cactgttaat ttgattagct ccatctccta aagtatgcac tcctactaca cggtgactag
    59401 catcataaac tgtagatcca ctagacccct ctaaagtatc aacttggtaa tccaagaaca
    59461 tgccatcatc acttaaaact tgttttttat ctgtatacat ttgatgaatt ttaaaattat
    59521 atgatagata gcctgtgata gtcacagtta ttcctgtcaa atttttttga ctagtaggaa
    59581 gacccaaagt ccctaatttt gcaccaatgg gctcttctag aattaataaa gccaagtcat
    59641 attcccttgc atccttagaa tttaaatttc taaattcctt caaataacga acttccttta
    59701 ctttgatctt tccaaatagt tcttgacttg gactaacagc cggaagaaca taaatatcat
    59761 ccgcttcttt cccatagtca tgtctgtagt agttgtgagc cgctgtaatt aacacattat
    59821 ctttaataaa attcgcactt cccctccctt ctacattcat tccatcggct actccataat
    59881 acttagataa aaccatagct gaagtcgaat acggatactg taaagtatta tcaattttaa
    59941 tcaaatcatc attaccgata atacttctga ttgcttttgg tagtatgaac catacgttgg
    60001 tgaaatctca gataatgaag aatcattaga ctctggacct ttttctagtg tctcacttac
    60061 ctcatattct tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct
    60121 agccaataaa gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat
    60181 tattgtatcc tcctaatgta attatagcgt actattctaa atttcttaat ctactataga
    60241 atcaagaaat ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt
    60301 tcaattaatg actgcgcttt tcaatcacgc tagaggtact tgcttgcttc tttgatacta
    60361 agttcagcca ttctttcctt gtttttctca ataaagcatg ttacccaagt gggattcgtt
    60421 ttggagtagt ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc
    60481 aagttatgaa gtagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac
    60541 tggtggtcaa tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc
    60601 aatgaaaatc aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttgg
    60661 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    60721 tctagttcag agtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    60781 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    60841 taagactgca ttgctttcaa atagttagca gccacatatt ggtattctct aggatccttt
    60901 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggaaaa
    60961 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    61021 gcatataggc ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    61081 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    61141 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    61201 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    61261 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    61321 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    61381 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    61441 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    61501 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    61561 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    61621 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    61681 ttttcaagcc caatcggacc atttcatggt catctactag taaaattttc atctttactc
    61741 ctttatcatt ccttatctaa caggggaata cggatatcaa ccgccagccc ttgcttggga
    61801 gctgtcaaga gttgaactgt tccagccata tcttcaaccc gctccttgat atttcgcagt
    61861 ccataactca agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc
    61921 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    61981 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    62041 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    62101 tttaagagaa tttgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    62161 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    62221 aactggatct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    62281 atcatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    62341 ttccgttcct tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga
    62401 agagcttctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    62461 ggatctgcaa cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    62521 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac
    62581 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag
    62641 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaacagg
    62701 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    62761 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    62821 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    62881 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    62941 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgaccctct
    63001 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag
    63061 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    63121 tcacgacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    63181 gaagaaagag gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    63241 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac
    63301 cagtgtagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    63361 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    63421 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    63481 acctcagtct gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct
    63541 tcttttaatt ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag
    63601 ttaagggaac acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact
    63661 tcttcaactg tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagactta
    63721 gcaccaaaaa ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag
    63781 agttcgacct tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc
    63841 cattgattga ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg
    63901 ccaccacgac ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc
    63961 ttggcatcca ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgctcgcta
    64021 taatctgcta gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat
    64081 tcctgcatga cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga
    64141 agccctaact cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga
    64201 ctagacttga cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc
    64261 gttacaaata aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt
    64321 cccttattac ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca
    64381 gcaaactctg tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc
    64441 agctccacct catcaaagct attataggaa cttttctgct caagggcata gaggatatgc
    64501 tcgtccttac gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag
    64561 atcggcccaa cgatttttta aggtttcggt tgattgcgca tcaaaactca aggcgatgcc
    64621 acagtcacca ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc
    64681 tttcaactgt ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct
    64741 ggctacttct acttgctcga taactttttc ggctttcccc tgctccaagg cttcgaccaa
    64801 agaaaccacc gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg
    64861 ctggaccatg tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc
    64921 taaagttggt ttcacttgtg agataaaaaa tccccaatca cgctccagaa ctgtcgccaa
    64981 gttttcttct tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa
    65041 atcctctgcc acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa
    65101 gacagcgcta gtcagcttga acaagagatt ctgatcaacc gaaagattat agagagccag
    65161 taaagccttg acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc
    65221 ttctcgttcc attttgccac agatttttag ggaaaaaggt cttaaattct gaccgcgaac
    65281 agcgaggaag tctcccatca aagcaatcgt ttcttgaatc aagctgtagt caggattagg
    65341 ccttaagtcc actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc
    65401 aatttcagcc ctcatataga tgggaatatc ctttatcaaa gctaactgcc ctggctctaa
    65461 aatagcatat tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac
    65521 tcaaatcctt tgtttttgac acaatcaagc gataacgctg accgaaaatt tctgataaat
    65581 gctccaagtc tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt
    65641 agcaggcctc tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat
    65701 ccgtcagata agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat
    65761 ttttctccgt taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat
    65821 cctgatagtc cttctcagac tgacgaaccc agtcgtcgaa agtcgtcgag gtttccacac
    65881 aaagtttcat cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa
    65941 tcatagctag tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg
    66001 ctcctagtgg tccataaaaa ctccgagaag aagagcctga ggcaaacttg gcttcctgcg
    66061 ctaactgact tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg
    66121 acaaaccact agaacttgag gacaggcccg ctgccgtagg catattgttt tgagtatcga
    66181 tacggacaaa gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat
    66241 gctcgacctc attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg
    66301 gtaaaggcga caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag
    66361 tagcaggcac catctctttt tcttttttct ttccccaata tttgataata gcaatatttg
    66421 cgtaggaacg tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa
    66481 tctttctgct agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc
    66541 tagcccacca ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa
    66601 aaagtctgcc tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag
    66661 gatttgtccc agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa
    66721 ttctcccaag gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat
    66781 ggcttcacga gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc
    66841 catctcaagt tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca
    66901 ggtcttagca tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa
    66961 gatttctagt acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc
    67021 cgctatgctg atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat
    67081 ctcacaacga atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat
    67141 ggacaaggta tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt
    67201 cacctccacc tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc
    67261 ccctattaaa attatcttac tatgtgcctg accgacacca actttttttg tcattttttc
    67321 cttttactag acgaaaaaac gtcttatttt tcatacaagt attaattctt tcctatctat
    67381 tttattatat tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattacc
    67441 gaacccattc accattataa ttgacagaat agccatctac aatcgtattc actgccaagg
    67501 cacctgagct ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag
    67561 aacgatgaaa gaaactccat accattaagt aaagaggaaa gtcatgaggg agcatgcgtc
    67621 attgacaacc tattttagtg acgtacaaag tttcattaac aagtactcgt ttcggccatt
    67681 tataggtgcg gtgtttgcag aaatagggtt caatcttcgc ccattcttga tcgtttaaat
    67741 cagtatcata tgctttgcgt gtcataactc tagtttaaca tttttttgtg aatacaggtt
    67801 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    67861 aaacttatgc acttaatttg acaactcaat atgtaaaaat atatactata
//
LOCUS       DAVBOH010000005        67652 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOH010000005 DAVBOH010000000
VERSION     DAVBOH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.005"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ873_000286"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VQ873_000286"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3106624.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1419..2195
                     /locus_tag="VQ873_000287"
     CDS             1419..2195
                     /locus_tag="VQ873_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3106625.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2205..2981
                     /gene="recX"
                     /locus_tag="VQ873_000288"
     CDS             2205..2981
                     /gene="recX"
                     /locus_tag="VQ873_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3106626.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            3070..3603
                     /locus_tag="VQ873_000289"
     CDS             3070..3603
                     /locus_tag="VQ873_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3106627.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(4044..4799)
                     /locus_tag="VQ873_000290"
                     /pseudo
     CDS             complement(4044..4799)
                     /locus_tag="VQ873_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ873_000291"
     CDS             complement(4937..6559)
                     /gene="groL"
                     /locus_tag="VQ873_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3106628.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ873_000292"
     CDS             complement(6575..6859)
                     /gene="groES"
                     /locus_tag="VQ873_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3106629.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(7129..7524)
                     /locus_tag="VQ873_000293"
     CDS             complement(7129..7524)
                     /locus_tag="VQ873_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3106630.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(7602..8363)
                     /locus_tag="VQ873_000294"
     CDS             complement(7602..8363)
                     /locus_tag="VQ873_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3106631.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(8396..9022)
                     /locus_tag="VQ873_000295"
     CDS             complement(8396..9022)
                     /locus_tag="VQ873_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3106632.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(9038..9355)
                     /locus_tag="VQ873_000296"
     CDS             complement(9038..9355)
                     /locus_tag="VQ873_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3106633.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(9352..9651)
                     /locus_tag="VQ873_000297"
     CDS             complement(9352..9651)
                     /locus_tag="VQ873_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3106634.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9936..10127)
                     /locus_tag="VQ873_000298"
     CDS             complement(9936..10127)
                     /locus_tag="VQ873_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3106635.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(10288..10962)
                     /locus_tag="VQ873_000299"
     CDS             complement(10288..10962)
                     /locus_tag="VQ873_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106636.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            complement(10967..11413)
                     /locus_tag="VQ873_000300"
     CDS             complement(10967..11413)
                     /locus_tag="VQ873_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106637.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(11527..12030)
                     /locus_tag="VQ873_000301"
     CDS             complement(11527..12030)
                     /locus_tag="VQ873_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3106638.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(12027..12389)
                     /locus_tag="VQ873_000302"
     CDS             complement(12027..12389)
                     /locus_tag="VQ873_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3106639.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(12515..14314)
                     /locus_tag="VQ873_000303"
                     /pseudo
     CDS             complement(12515..14314)
                     /locus_tag="VQ873_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(14331..14800)
                     /locus_tag="VQ873_000304"
                     /pseudo
     CDS             complement(14331..14800)
                     /locus_tag="VQ873_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(14924..15640)
                     /locus_tag="VQ873_000305"
     CDS             complement(14924..15640)
                     /locus_tag="VQ873_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3106640.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ873_000306"
     CDS             complement(16521..17936)
                     /gene="ply"
                     /locus_tag="VQ873_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3106641.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(17947..18279)
                     /locus_tag="VQ873_000307"
     CDS             complement(17947..18279)
                     /locus_tag="VQ873_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106642.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(18350..18958)
                     /locus_tag="VQ873_000308"
     CDS             complement(18350..18958)
                     /locus_tag="VQ873_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106643.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18971..19429)
                     /locus_tag="VQ873_000309"
     CDS             complement(18971..19429)
                     /locus_tag="VQ873_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3106644.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            19554..19953
                     /locus_tag="VQ873_000310"
                     /pseudo
     CDS             19554..19953
                     /locus_tag="VQ873_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20718..20978)
                     /locus_tag="VQ873_000311"
     CDS             complement(20718..20978)
                     /locus_tag="VQ873_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106645.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(21037..21588)
                     /locus_tag="VQ873_000312"
     CDS             complement(21037..21588)
                     /locus_tag="VQ873_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106646.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(21578..21775)
                     /locus_tag="VQ873_000313"
     CDS             complement(21578..21775)
                     /locus_tag="VQ873_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106647.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(21779..22363)
                     /locus_tag="VQ873_000314"
     CDS             complement(21779..22363)
                     /locus_tag="VQ873_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106648.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(22761..23186)
                     /locus_tag="VQ873_000315"
     CDS             complement(22761..23186)
                     /locus_tag="VQ873_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106649.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(23315..23674)
                     /locus_tag="VQ873_000316"
     CDS             complement(23315..23674)
                     /locus_tag="VQ873_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106650.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(23720..23926)
                     /locus_tag="VQ873_000317"
     CDS             complement(23720..23926)
                     /locus_tag="VQ873_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106651.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(23913..24074)
                     /locus_tag="VQ873_000318"
     CDS             complement(23913..24074)
                     /locus_tag="VQ873_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3106652.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ873_000319"
     CDS             complement(24433..25389)
                     /gene="lytA"
                     /locus_tag="VQ873_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3106653.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(25765..27135)
                     /locus_tag="VQ873_000320"
     CDS             complement(25765..27135)
                     /locus_tag="VQ873_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3106654.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ873_000321"
     CDS             complement(27442..28608)
                     /gene="recA"
                     /locus_tag="VQ873_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3106655.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(28663..29919)
                     /locus_tag="VQ873_000322"
     CDS             complement(28663..29919)
                     /locus_tag="VQ873_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3106656.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(30004..31020)
                     /locus_tag="VQ873_000323"
     CDS             complement(30004..31020)
                     /locus_tag="VQ873_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3106657.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(31028..31546)
                     /locus_tag="VQ873_000324"
     CDS             complement(31028..31546)
                     /locus_tag="VQ873_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106658.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ873_000325"
     CDS             complement(31536..31979)
                     /gene="tsaE"
                     /locus_tag="VQ873_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3106659.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(32065..32685)
                     /locus_tag="VQ873_000326"
     CDS             complement(32065..32685)
                     /locus_tag="VQ873_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106660.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(33068..33931)
                     /locus_tag="VQ873_000327"
     CDS             complement(33068..33931)
                     /locus_tag="VQ873_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3106661.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            34435..36450
                     /locus_tag="VQ873_000328"
     CDS             34435..36450
                     /locus_tag="VQ873_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3106662.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            36452..37084
                     /locus_tag="VQ873_000329"
     CDS             36452..37084
                     /locus_tag="VQ873_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106663.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            37225..37503
                     /locus_tag="VQ873_000330"
     CDS             37225..37503
                     /locus_tag="VQ873_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3106664.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ873_000331"
     CDS             complement(38012..38425)
                     /gene="ndk"
                     /locus_tag="VQ873_000331"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3106665.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ873_000332"
     CDS             complement(38536..42213)
                     /gene="rpoC"
                     /locus_tag="VQ873_000332"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3106666.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ873_000333"
     CDS             complement(42246..45857)
                     /gene="rpoB"
                     /locus_tag="VQ873_000333"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3106667.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            46273..46343
                     /locus_tag="VQ873_000334"
     tRNA            46273..46343
                     /locus_tag="VQ873_000334"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46305..46307,aa:Cys,seq:gca)
     gene            complement(46541..47872)
                     /locus_tag="VQ873_000335"
     CDS             complement(46541..47872)
                     /locus_tag="VQ873_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3106668.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ873_000336"
     CDS             complement(48163..48987)
                     /gene="endA"
                     /locus_tag="VQ873_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3106669.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(49026..49214)
                     /locus_tag="VQ873_000337"
     CDS             complement(49026..49214)
                     /locus_tag="VQ873_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3106670.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ873_000338"
     CDS             complement(49207..50490)
                     /gene="murA"
                     /locus_tag="VQ873_000338"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3106671.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(50514..50744)
                     /locus_tag="VQ873_000339"
     CDS             complement(50514..50744)
                     /locus_tag="VQ873_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3106672.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(50802..51839)
                     /locus_tag="VQ873_000340"
     CDS             complement(50802..51839)
                     /locus_tag="VQ873_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3106673.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ873_000341"
     CDS             complement(51823..52311)
                     /gene="coaD"
                     /locus_tag="VQ873_000341"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3106674.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ873_000342"
     CDS             complement(52301..52840)
                     /gene="rsmD"
                     /locus_tag="VQ873_000342"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3106675.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(52905..53897)
                     /locus_tag="VQ873_000343"
     CDS             complement(52905..53897)
                     /locus_tag="VQ873_000343"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3106676.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(54008..54691)
                     /locus_tag="VQ873_000344"
     CDS             complement(54008..54691)
                     /locus_tag="VQ873_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3106677.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(54747..55487)
                     /locus_tag="VQ873_000345"
     CDS             complement(54747..55487)
                     /locus_tag="VQ873_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3106678.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            55521..55799
                     /locus_tag="VQ873_000346"
     CDS             55521..55799
                     /locus_tag="VQ873_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3106679.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            55877..56803
                     /gene="yidC"
                     /locus_tag="VQ873_000347"
     CDS             55877..56803
                     /gene="yidC"
                     /locus_tag="VQ873_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3106680.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ873_000348"
     CDS             complement(56878..57672)
                     /gene="pflA"
                     /locus_tag="VQ873_000348"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3106681.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(57798..59048)
                     /locus_tag="VQ873_000349"
     CDS             complement(57798..59048)
                     /locus_tag="VQ873_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3106682.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ873_000350"
     CDS             complement(59115..59942)
                     /gene="purR"
                     /locus_tag="VQ873_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3106683.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(60209..61150)
                     /locus_tag="VQ873_000351"
     CDS             complement(60209..61150)
                     /locus_tag="VQ873_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3106684.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(61140..62396)
                     /locus_tag="VQ873_000352"
     CDS             complement(61140..62396)
                     /locus_tag="VQ873_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3106685.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(62398..63060)
                     /locus_tag="VQ873_000353"
     CDS             complement(62398..63060)
                     /locus_tag="VQ873_000353"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3106686.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(63023..63679)
                     /locus_tag="VQ873_000354"
     CDS             complement(63023..63679)
                     /locus_tag="VQ873_000354"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3106687.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ873_000355"
     CDS             complement(63690..64568)
                     /gene="rsgA"
                     /locus_tag="VQ873_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3106688.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(65161..65934)
                     /locus_tag="VQ873_000356"
     CDS             complement(65161..65934)
                     /locus_tag="VQ873_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3106689.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ873_000357"
     CDS             complement(66624..67496)
                     /gene="rsmA"
                     /locus_tag="VQ873_000357"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3106690.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        19930 a        14991 c        12403 g        20328 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggttttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atatgtctat tataccatgg
     1381 agtttctaag atatttaaga atatgttaca ataaaagcat gaattcaaaa acacctcgct
     1441 ttagtatact agatttccct gaacaattac gaagctatat caagggagct aatctctctg
     1501 atagttcttc tcattcaagt gcaactgtcc tatatataga ttcaggttac tatttaaaaa
     1561 tagatcaaaa aggcagatta gctcaagaaa ctaagattgc aagttggttc gaaactgaag
     1621 gattgggaac tccagtgatt acctatttat cagcaaataa ggacttcctt ctgactaaag
     1681 aagccattgg cagcaacgct ctcgcttttt taaatcaacc cgaaagactc tgtcaaaccc
     1741 tggctcaagc attaaacaaa cttcacagtc ttaaaccaca atcttttccg tcggaaaatc
     1801 atctgaagcg ttataaagaa aaagccttaa aaaactatca gaaggggact ttttataaca
     1861 agactcttct gcctcaattt cacattcaca gtcgtgaaga agcttaccaa ctgatacaag
     1921 agaaaggtta cattctcaaa gctgatgctt ttattcatgg agatgcctgc ctgccaaatt
     1981 tcatcttgaa ggatgcctct catttttctt gctttattga cttgggattg gctggtttta
     2041 gtgaccgaca tatcgacctc ttttgggcaa tttggtccct tcattacaac ctacaagatg
     2101 ctacgtatgc tgaattattt ctcgactatt acggtagaga atatgtaaat atggataaac
     2161 tacgacttgt tgcagctttc gaagcattta gatgaaagga aattatgaaa atcacaaaac
     2221 ttgaaaagaa aaaacgtctc tacttgatgg aactagatgg acagcaaacc tcttatatca
     2281 cggaagatac cattgtccgt tttatgctgt ctcgagataa ggtcattagt aaagaggaac
     2341 tgaccgagat tcaggatttt gcccagtttt cttatggtaa gaatctcgct ctctaccact
     2401 tatcctttaa agcacgcact gaaaaagaag tcagagaata tctgaaaaaa tacgatattg
     2461 ataaaaacat cgtttctcaa gttattgcta atcttaaaga agataagtgg attaatgatg
     2521 gtcagtacgc ttatgctatc atcaatacca atcaactttc aggagacaag ggtccttatg
     2581 tgctgactca gaaactagct caaaaaggga tttcaaaatc tactatagaa gagaacttga
     2641 aagaatttga tttttctgaa gttgctcaac gtgtagctaa taaactattg aaaaaatatg
     2701 agggaaaact tccatctcgt gccctgcaag ataagattat ccagaacttg actaacaagg
     2761 gcttctctta ttctgatgct aaaattgcct ttgacgactt agatagccaa gttgaccaag
     2821 aaacgactca agaactcatc ttcaaggaac ttgataaaca atatagtaag tatgctcgaa
     2881 agtatgaagg atacgaactg aagcagcgtt taactcaagt tttagcacga aagggctacg
     2941 atttttcgga tatagcaagc gctcttagag aatatcttta atatttccaa gtgaaattca
     3001 cagattttag gtaattttat ggtacaatag taaatgataa acttataaat tgtagaaagt
     3061 tggttagtta tgaagcttcc aaaagaaggc gactttatta caattcaaag ttataagcat
     3121 gatgggagtc tccaccgaac ttggcgggac accatggtac taaaaacaac agaaaacgcc
     3181 attattggtg tcaacgatca tacacttgtt accgaaagtg atggtcgtcg ttgggtcact
     3241 cgagaaccgg ctattgttta ctttcacaag aaatattggt ttaatatcat tgccatgatt
     3301 cgtgataatg gaacttctta ctattgcaat atggctagcc cctactatct ggatgaagaa
     3361 gcactgaagt atattgatta cgatttggat gttaaaattt ttacagatgg ggaaaaacgt
     3421 ctcttggacg ttgaagagta cgagcgtcac aaacgcaaaa tgaattattc tgatgacttg
     3481 gactatattt taaaagaaca tgtcaaaatt cttgttgatt ggattaacaa tggacgtggt
     3541 cctttctcag aagcctatgt aaacatttgg tacaagcgct atgtagaact aaagaatcgg
     3601 taaagttgtc aaaggtcagg aacaaaatcc tgaccttgtt tttttggtag tataaaataa
     3661 attgtgtaaa cacaaaaagg aataaatcca ttatagcaga gttacaacac attactagaa
     3721 agagatttat tcctacgact cagtttggca tgcttaactt cctaactcaa aaacaaagca
     3781 tcgattaatt tatccgttct tcttttgaaa cagatttgaa ctgataattg ctcgttttaa
     3841 tttaagaagc tcttttgagc aaaacttcat ttttttaaga gtccaacaat ttctgtctat
     3901 cgcttttcta ctagcaaaaa aacctacctt gaggcaagtt ttcatttata tatctaattt
     3961 cgtaatagta tagtaaaatg aaataaggac agtcaaatcg atttctaaca atgttttaga
     4021 agtaaaggtg tactattcta gtttcaatct actataaatt tgatatgaga atagtctttc
     4081 tcaacatcct tacccaacaa gaatgctgta gcgtccttct taacttgaac caggtcaata
     4141 ttctgggctt gggctgcata gacgcagcca caataacatt gacgatagat atcatactcc
     4201 tcacacatct ctactgaacg tttgtagcct tgatttttct tgaaatcgtt gggaagatag
     4261 tgggtcgtgt aaattttttg cacatcgatt ccgatgctgt tgatggtttg agaattctta
     4321 tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc ccaagtccat agccacttgc
     4381 gctgttttat ccagtcggta gtcaaaacaa accttgcaac ggtcgccacc ttcgggctcc
     4441 tcctctagtc ccctaactag ttttcggtat taattgggtt cgtagggagc ttctaggtac
     4501 tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa atttcttggt gacatagacc
     4561 cgcttatggt attctacctt gggatggata ttagaattgg caaaatagat ggtcacatct
     4621 gcatacttgg tcaaatattc tagtgtatag gtactacaag gggcacagca aacatgcacg
     4681 agaatggttg gccgttgctc atttttctac catacttcta ccattttctg catgacacgg
     4741 tcataattaa tcttctgatt ggggggcatc ttgcacagaa ttttttctac atcgatcatg
     4801 ttcttctcct ttttctagtc ttattttatc atataagtta ggagagctca aatcaattta
     4861 gaagtgaata ttataaaaag aagggttagt cattccctcc ttttgtgttt tttataagtt
     4921 gttttctata gaatgcttac atcatcccgc ccatcatgct tggatccatt gctggagctg
     4981 gggctactgg ttctggttta ttggctacga ctgcttctgt tgtcaaaatc aagctggcta
     5041 cagatgctgc attttgtagg gctgaacgac tcactttaac tggatcaatg ataccttgat
     5101 caatcatgtt aacccactcg ccagttgctg cgttgaatcc tataccaagc tcagcatttt
     5161 tcaaacgatc gataacgata gatccttcaa atcctgcatt gtgagcaatt tgacgaacag
     5221 gttcttccaa agcacggaga acaatattac gtcctgttac ttcatctcct gtcaattcca
     5281 aggtagcaac agctggaatc acattggcaa gagctgttcc accacctgca acaatacctt
     5341 cttcaacagc tgcacgagta gcgttgaggg catcttcaat gcggagtttc atttctttca
     5401 actcagtttc agttgcggct ccgaccttaa taaccgctac accacctgac aatttggcca
     5461 agcgttcttg caatttttca cggtcaaatt cagaagttgt agtttcgatt tgagacttga
     5521 taaccgcaac acggtgagaa atcgcttcag gatttcctgc accttctaca ataaccgtgc
     5581 tatctttgtc cacggtcact ctcgctgctt gaccaagagc ttcaattgtc gcatctttca
     5641 actcaagacc aaggtcttct gtgataactg ttccgcctgt taagatggcg atatcttcaa
     5701 gcatggcttt gcgacggtca ccaaaaccag gtgccttgac tgctactacg ttgaaggttc
     5761 cacgaatctt gttcaaaaca agagttggaa gagcctcacc atccacatca tccgcaataa
     5821 tcaagagtgg acgattgctt tggagaatgc tttccaaaag tggcaagatt tcttggatat
     5881 tggaaatttt cttgtctgta atcaaaatgt acggattttc aaggtcagcc accatttttt
     5941 cgctatctgt caccatgtac tgtgaaaggt aaccacggtc aaactgcatt ccttctacga
     6001 cttcaagctc tgtttccata ccacgtgact cttcgatggt gatgacaccg tctttgccaa
     6061 ctttttccat tgcttcagag atgtactcac caactttttc agaacgagaa gatacggctg
     6121 caacttgagc gatagcttct ttattggcaa cagggatggc gttgtttttc aaagcttcaa
     6181 ctgctgcggc aactgctgtt tcaatcccac gacgaatacc gattggattt gcacctgctg
     6241 tgacgttttt gattccttca cggacgatag cttgggtcaa gactgttgca gtcgtagttc
     6301 cgtcacctgc gatatcattg gttttagaag ctacttctga tactaactta gcacccatat
     6361 tttcaaaatg gtcttccaat tcgatttctt tggcaatagt cacaccgtca ttggtaatca
     6421 atggtgagcc aaatgatttt tcaagaacga cattgcgacc ttttggtccc aaggttactt
     6481 taacagtgtc tgcaaggata tcgacaccac ggaccatagc tgaacgggca tctgatgaaa
     6541 atttaatttc ttttgacata cttactttct ccttctattc ttcaatgatt gccaagatgt
     6601 tagcttcgcc tacgatgatg tacttttcat cgccatcttt gacatcaaga cctgcgtggg
     6661 cttcaactaa gacacggtct ccagttttaa cacttggagc aaccaagtca ccgttcaagg
     6721 tacgaacacc ttgtccagta gccacaactt gggctgtttt ggttttttct tgggctgaac
     6781 ctgcgagaac aaagccccca acggtttgtt ctttttcttc tatttttaag accacacggt
     6841 cccctaatgg tttcaacatc tgatttcctc cataatgaga tagatattat tagcactctt
     6901 tatacctgag tgctaattca tagttctatt gtatcactta gtcagaaata atcaagaaaa
     6961 aagtctgact ttctcaagat aaaaagcctg agaccaactc agacttttta atgtttatac
     7021 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgctcaaa gcattgcttt
     7081 gatgttgtgg ataaagctaa cgtggtttga agagattttc gaagagtatt aaaatggcaa
     7141 ttcttcctct tccaagacta aatctgccaa atcttggcct gcattatttt cacgcatggc
     7201 acgttgagca cgactttcca agagttggaa tcctgttaca agtacttcgg tcacgtagtt
     7261 catttggcca tttttctcaa agcgacgggt acgcaattct ccatcaacgg aaatgagact
     7321 acctttggtt gcgtagcttg ccaaagtttc tgctagtctg ccccatagga ccatattgac
     7381 aaaatcagct tcacgttcac cgttttggtc tttgtaacga cggttcacag cgatagttgc
     7441 tcgcgctacc gacttgtcat tgttggtttt gtgcaattct ggtgtagacg ttaaacgccc
     7501 aatcatgata actttattat acatattttc ttcctcctac ttatctattc gtaggaaatc
     7561 aaaaaaagtt acagaaattt gtaacttttc gaggaaattt cttatttttt atgaatcatg
     7621 aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac acggcgaggc
     7681 tgactggtca catagactac tgtgtctgca atatcctgag cttgcaaggc ttctattcct
     7741 tggtaaacgg acgcagctcg ctctttatca ccatgaaaac gaacagttga gaaatctgtt
     7801 tcgacaatcc caggctgaat ggttgtcacc ttgatatccg ttgcgatggt atcaattcgc
     7861 agtccatccg aaaaggtctt aaccgcagcc ttggtagctg agtaaacagc ggcaccagca
     7921 taggcgtaga ttcctgcggt tgaccccata ttgataatat gaccttgatt gacttttatc
     7981 attgctggca agaaacagcg agtaaccgcc atcagacctt taacattggt atccaacatg
     8041 gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc cagtccggcg
     8101 ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca aacagtcttc
     8161 accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt tggaaagctt
     8221 actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt tagaacgaca
     8281 tcctcaccct gctccagata agcacgcgca atcgcttcac cgattcctga ggttgctccc
     8341 gtaatcacta cattttttgc catcttattt ccttctatca gatgctgaca agttcctagg
     8401 cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct gataattcaa
     8461 gcaccccacg tttttgcgga gcatttggca aatgcaattc acgaggacta cacatcatcc
     8521 caaaactctt ttcaccacga agttcgcctg ggaaaatgaa attccctttt ggcatcatgg
     8581 caccaggaag agccacaatg gttttcaacc caacacgcgc attaggtgct cctgcaacga
     8641 tttgcactat cttgtcactt gcgactgcaa cttggcagat gttgaggtgg tcactgtctg
     8701 gatgagctac catctcgaca atttcaccaa caacaaactt aggttcctta tcattaacaa
     8761 tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa acgagcgact tgctcatctg
     8821 ataaaaagac ttgaccgcgc tctgcaattt caaacaagct cgaaacctca aaaatgttcc
     8881 aagctactgt ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca
     8941 cattcagttt ggcatctccg ctatttttca cgatgaccat aaggacatca ctgacatgtt
     9001 ctttgttata cgtaaaaatc attgtttcct ttttctccta tttcaatcct gctaaaaaat
     9061 cgttaatttg ctccttactt ttacggtcgc gattgacaaa acgaccgatt tccttgtcct
     9121 tttctagaac aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat
     9181 actgatctcg gtccattcga ataaaggtga actctggatt ggtctcttca atctctggta
     9241 aggcaggata aatataacga caatcgccac accagtctgc cacaaaaagg aagaccttct
     9301 tgcccgcttt ttccactaaa gatgctaatt cttctaaact tgctggctgt atcataagac
     9361 ttcctcctca tagactaggt cttcattttc atagacaaag gtataatgac ggccatcctc
     9421 aaaaatgacg ccaccaacca agctctccag actgctttcg taaacttgaa cataaagggt
     9481 cgcaatttcc cccatgtcgg aaaaatggtc tcgcacaatc tctgtcaact cttcctgagt
     9541 cttcatgagc ttacggtcat ctgcaacttt tttcgtagca agagcaaggc ttccgatacc
     9601 tagcagagcc aagcctgcca tccacatttt tttagctttc ataccattca ttttaacaca
     9661 aaaaaggctt caggacaaat gaggaagcag cagaaaagca agtaaaaagc ctcttccttt
     9721 aaggaaaagg acttcttata ctaagagcaa actagaaagc tagccgcagg ctgctcaaaa
     9781 cacggttttg aggttgtaga taaggcgacg ttgacgtggt ttgaagagat tttcaaagag
     9841 tattattctt attgccaggc acctaagttg ccaacgtagt aaccatcagg tgtgtaggta
     9901 ttgcgaagca tcttacctga tgaagccaga taatactact tgccattgtc tttgacccaa
     9961 tcattcgcaa tcatggaacc agaagaactt acataatacc attctccctt gtcataaacc
    10021 caagtactga ctttcatggt tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt
    10081 cgttttttaa aagcattcga cactacatca tctacgctgt agtacataga tacatcaaac
    10141 gtaaaagcca aaatatcgaa aaatatacaa cttttaaagg cagcatttca ttttttaaag
    10201 tctaacaacc atagaactga aatcagagca aggcatcaat ttcctactct tagtacgcct
    10261 attttgatgg ttgaagtgaa gattttttta tttagcgtag acaatttcca acttcccaaa
    10321 agccacatct ccacggataa tcaaggtttt gctggttggg gctacaggag cgtccgcctt
    10381 ggctgcacca aaggatgttt ctactttcaa atcgacacgc cagtgttgcg gaacatagac
    10441 agttgcatta ccaaaagcta cttcaatatt taaagttgca aaatcaccta acatctctgc
    10501 attgtcatag tagatttttg cattgccaaa accaacttct acttggtctt ctaccaattc
    10561 ttggtcttgc ttgtagaaag tccctgtccc aaaagcaact tccttatcta taagaatgtt
    10621 tttttcacca tcataccacc attttttccc attccaagtt ctgttagaat gagtcaacat
    10681 atttactccg agaacgatta gaactcctgc ccagattagt gtctggtttg gaatcggtaa
    10741 aatgccataa aagtggttag caatcattaa ggctactaga gctgtaaaag aggctgaagt
    10801 taagtggcga cgcaacaaag ctccaactga ttggtaggca aaaaaagcaa taccaatcaa
    10861 gggccaaatg tgccctccta gagaagggat tccaaaattt ccttgtacta atattaaagc
    10921 tgctagtaca agcaacacaa taccaaatgc tttctttttc atgttcttac ctcatatttc
    10981 ttagattttc ttttaggagg gattggtaat gccgtgacac atgaacctcc ttgtgggttt
    11041 gataaaagga aatggtgccc gttcctgaaa aggacttgtc caccgaatag atttgccgaa
    11101 tattaacgat cgttgacttg gatactcgac taaaatagcg aggaaggata gcctctaact
    11161 catagagttt gagccgaact tcgtaggcat ttttctgggt atgggcataa atcttgctac
    11221 cttctgtctc aaagaagaga atttccgaca agtccagata atattcaccc gtccccttgt
    11281 aaaaaatcaa cctaggagac ttggattctt gcaagagccg ttgcaagtct gcaatttcat
    11341 ctgtcaaagt gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa
    11401 ttcgtaactt catcacatct cctttctgac tctactatat caaagctaag ttaggaatac
    11461 aagggcaaaa aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact
    11521 tacatgtcag aataagaaga aaaggaatcc ccacaccaga ccacaagcat agccaaccaa
    11581 gacatccttg ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa
    11641 gatcaagcat actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt
    11701 tgcagaaaag acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg
    11761 acagatatcc caagtttcat aaggtctcgg gtgattgatt tttttacgaa acagggacaa
    11821 ggccacaaaa cctgatgcag gaataagcac ataaactcca acttgctgac caagtcctag
    11881 ttgcaggtaa gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa
    11941 acgattgaaa ctgcgtaata ggaataaaag aattggacga ctagttagtc tggatctgat
    12001 atttcgatac cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt
    12061 tgagatgttt tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc
    12121 atcagaggat catcaatttc ctcaatacgg acaccgcaaa tcttccctgt aattgcaatt
    12181 cgttcaggga cataatatgg tgcttgtcga aaaaaatctc cgtaagtaac atccctatcc
    12241 agacaagtaa gaacgtcact cacttcatac cctgtcaacc aactggtcac ttggtgaact
    12301 gactctgcct ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca
    12361 aatttcatat tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa
    12421 taagaaaaag aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa
    12481 attgactatt gtacaagtca gcgtagaagc caccttacac catcagttcc tcatagttgc
    12541 cttgctcgat gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg
    12601 acaagcggtg ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt
    12661 ggatcaattc ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg
    12721 gtgcatcctt aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg
    12781 tcacggtgtc atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa
    12841 ttcccacagc cttactagct tccatcattc gttcatcact aatccctatt tgattataga
    12901 tgagattgtc tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg
    12961 catcatgcac ttctgaacgc gtcatagcct tggtatccac accatcaatg cgaatacttc
    13021 ccttatcaat ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagccccag
    13081 tcggcccaac aatggcaacc ctttgaccag catgagctgt cgcagagaag tcatagtctt
    13141 gaacattgac accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca
    13201 gattgaccag agttgattta ccagaaccta ttgacccaat aaaggccact gtttgaccag
    13261 tttctgcttt aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg
    13321 tcacatcctt aaactcgacc tgacctttga agttttcatc agtcagctgc acttgagcag
    13381 ggttttggat agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag
    13441 ttcggggaag aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg
    13501 cataagacat gaaaacaatc atgtcactaa agaaaggcag acgcgctatc ggagcagcgt
    13561 cgttaatcac ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca
    13621 tcatgatagg attcaaaata gccataagac ggttgacaaa caaattttaa cgggtcaatt
    13681 catcatttac tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga
    13741 cacgaatacc tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa
    13801 tcaaggactg ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa
    13861 tcactgccac aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag
    13921 cccagatagc cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt
    13981 gaacttgagt aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa
    14041 tctctgtctg cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat
    14101 aagaagccgc cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa
    14161 agggcattcc catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac
    14221 tacctagcaa atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg
    14281 aaaagcaagt aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt
    14341 tggctaattt ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga
    14401 actttctcaa aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg
    14461 cgttcaaaaa agccttaacc tgttgcatct gagaacgtgc tttgtccgtc agacgaacaa
    14521 acttagcccg cttatcaaca ggactcgcct ccaattccac caaaccattt tgcactatac
    14581 gcttaaccag attactagca acagacttgg taatattgag ttcctgctcg atatctttaa
    14641 tcaagaccaa gtcttggttt ttctcgcgat tatccaaaaa acgcacaacc tgaccttgcg
    14701 gcccacccat aaattcaatg ccgcaacgtt tggcttcctt ttgcaccatc aggtaaattt
    14761 gatgaccaaa acgcttaaag actaacatcg gtttatccat aatctccccc ttctaaataa
    14821 aaatagttct ctggagaata attaaatttc tatgagaact attttcttga ttaaaaaaat
    14881 cccaagtgat tttctcactt aggatcatgt tctataggtt aaattaaaac ccatctacgt
    14941 tcgtataaat cttttggacg tcttcgtcgt cttcaagaac gctgtaaagt ttttcaaagg
    15001 tttcaaggtc ttcgcctgac aattccactt ctgactgagg aatcatttcc aattcagtca
    15061 cttggaattc ttcaatacca gactcacgga gagcaacgat agccttgtga aggtcagttg
    15121 gcgctgtgta aactgtgatt gtaccttctt gtgcttctac gtcatccaca tccacatccg
    15181 cttcgagcaa ttgctcaaag actgcgtccg catcttcacc tccaaataca ataacacctt
    15241 tgttgtcaaa aaggtaagaa acagaacctg aagcgcccat gtttccgccg tttttaccaa
    15301 aggctgcacg gacattggct gctgtacggt taacgttaga agtcaaagta tccacaatta
    15361 gcatagagcc atttggccca aaaccttcgt aacgtccttc tgtaaaggtt tcgtctgtgt
    15421 ttcctttggc tttatcaatc gctttatcga taatgtgttt tggcacttgg gcttgtttag
    15481 cacggtcgat aacgaatttc aaagctgagt ttgattctgg atctggatca ccttttttag
    15541 ctgctacata gatttctaca ccaaattttg catatacttt agagttagct ccatctttag
    15601 ccgttttctt ggctacgata ttggcccatt tacgtcccat taggaatctc cttttttcac
    15661 attttaatct ttcttattat aacacaagtt tttttgattt tcactagagg aaatggattt
    15721 tattagcaaa tcaagctagg atagcacttt acctgctaag atggtcttac ctttctatct
    15781 ttatcaacag acactcatcc acattcaaaa aacaaactag accattatct gcaaatagaa
    15841 agtttcagcc aagtttgaca aagtcagctc aaattactgt ttgaagtttg tagatataag
    15901 cgacaaaaac aatcatactg caccttttgt tgacagtcta ctccagacat atcatagttc
    15961 aagtaaatac tttgaaatcc aacagttctt ataggcgcta ttgtattcta agaaatcaat
    16021 agaagagttt ctaagcaaac ctctaatact caataaaaat caaaaagcaa actagaaagc
    16081 tagccgcagg ttgctcaaaa cactgttttg aggttgcgga tagggctgac ctggtttgaa
    16141 gagattttcg aagagtataa tttacgtgtt cccaagatgg agaaattaga ctagtacact
    16201 ggcacttcta aaccattgct agcaattgat ttgttcatat ttaatttcat tttttccata
    16261 aatgggtatt agatataaac agcaaaatat ttccgatacg tgtcattctt gaatttccaa
    16321 tcatctaaaa caagtaaagg ataatcaatc ccctgtatat caaggaattg gctacccttt
    16381 ttactttttt acacattctg tttgatagat tcattttaac atcacgagca tactccaatg
    16441 gaaatcgcta ggcaagagat aaactttcag atatccgcag agagatcatc gcctcttttt
    16501 gtcgcaagca ttctcctcta ctagtcattt tctaccttat cttctacctg aggatagaga
    16561 gttgttcccc aaatagaaat cgtccgctta cgcactagtg gcaaatcggt tttttcataa
    16621 accgtacgcc accattccca ggcaagcccg gtacactctc taattttgac agagagatta
    16681 cgaacattcc cttttaaagg aatactagtg gtaaagtgag ccgtcaaatc ctgcccattt
    16741 ctgtcccaag ccttaggagt caagacttcc ttaccttgat gatcatagga taattcatcc
    16801 caagtaatat aatattgggc aacataggca ccactatgat ccagcagtaa atctccgttt
    16861 ctgtaagctg taaccttagt ctcaacatag tctgtactat tttgaaaggt cgcaactaca
    16921 ttgtcacgta aaaaagaagt tgtataggaa atcggcaagc ctggatgatc tgctgtaaag
    16981 cgactgcctt cttgaatcaa gtcctctacc atatccacct tgcctgttac aactcgggca
    17041 cccgaacttg ggtcgccccc taaaataacc gccttcactt ctgtattgtc caaaatctgc
    17101 ttccactctg tctgaggagc taccttgact ccttttatca aagcttcaaa agcagcctct
    17161 acttcatcac tcttactcgt ggtttccaac ttgagataga cttggcgccc ataagcaaca
    17221 ctcgaaatat agaccaaagg acgctctgca gaaattcctc tctgttttaa atcctctacc
    17281 gttacagtat cttgaaacac atctcctgga tttttaacag catctacgct gactgtataa
    17341 taaatctgct taaaattaac aatctgaatc tgcttttcgc ctgaatggac agagttaaaa
    17401 tcaatatcaa gagaattccc tgtcttttca aagtcagaac caaacttgac cttgagttgt
    17461 tccatgctgt gagccgtgat tttttcatac tgcattctag ctgggacatt attgacctga
    17521 ccataatctt gatgccactt agccaacaaa tcgtttaccg ctccgcgaac acttgaattg
    17581 ctggggtctt ccacttggag aaagctatcg ctacttgcca aaccaggcaa atcaatacta
    17641 taagtcatcg gagcacgatc gaccgcaaga agagtgggat tattctctaa caaggtctca
    17701 tccactacga gaagtgctcc aggatagagg cgactgtcgt tggtagctgt tacagaaata
    17761 tcacttgtat ttgtcgacaa gctccgcttc tttctttcga taacaacaaa ctcatcgggt
    17821 agctgattac cctctttgat gaaacgattt tcaatacttt ctccctgatg ggtcaagagt
    17881 ttctttttat cgtaattcat agctagtata aagtcattta ctgctttatt tgccatcttc
    17941 tacctcctaa taagttcctg gattgagttg cataaactca gacttgttca gcgaaatcag
    18001 ccgtggttgg actaagtgat ccaaaatttc ctcgtacaat tcttctgaga cattgcgtcg
    18061 ccgtctggct agataagaag tcggaataac cgtattatcc aacataaata ccttatctaa
    18121 gtcaatcaag gttggtcttg taaaaggatt acgagctaga tccggctctt ctatcataaa
    18181 gttcttgacc aaacgtctgg tcaagagagc tggtttgaag gtctgatttt taaccaactc
    18241 tttgttttta gtcatgctgt tgtcaataca gatatacata tgattcttca cagccaaatc
    18301 gctactaata gtcggaaaag gcaaataaag agctacaaca tctcctctct taatcaagca
    18361 agagcacccc cttttctcct aatgtaacat agacaggatt gaccaagtct tctgattgac
    18421 tcagaatttc caaagtttga gtttggcgcg ctgtcaattt agtagcatct tgtctcttca
    18481 atacaaaatg cttgtcgcca ataaccttga caatataatc cttctccaaa gctgactggt
    18541 aaatccacat cagatgttgt ctgtcctgag aactcaagag agaaggattt tcaagcctcc
    18601 cgatagtctg ataaaaatca aaaacaggag ctaactcctg ccaatctgat tggctagttg
    18661 tcaaggctag aaaaagggct ttgcgagctg atacttcttg gttagccttg agagttactt
    18721 tcccctccaa gttttttaga aatcgggaaa ctccagaaag caaatttttc tctaactgcg
    18781 agaaataaaa acctttcgtt cccagacata agtctttcat gtcgctttct ctagcaaata
    18841 agagctcaaa catttgatag taaaagaaaa atatctggca ctgggtcgcg ctcatctttt
    18901 ccttatcggc ttcttttttt aaccagagca agggcgacag gtaactggat tgagacattt
    18961 cctctacctc ctactctttt ttaactggag catctgcact agctgccact tcttttgact
    19021 ggatactttc ccactggtta atctcctctg agataagacc ttcgcatgtc ttgacaaata
    19081 gggcaaaagc cttggtcttt cctgcatatt tctccgtttg gcattgatag aggaattttt
    19141 ctttctccag gagttgcgca gttttttggt aagaaatcca attttccttt gcattataca
    19201 aattgataat cccctcacac agcaagccga gactggataa ggcaaccgaa atcaaacggt
    19261 agcgatcacc tggcatagga atagcacaaa agacagctat gaggaaacct gccacgattt
    19321 ctgttatttt taatacctta tagcgcctac gatgttgaac gcttttcttt aaaaaatgag
    19381 ctatctgtac gtctaatcgc tctgtcaggt acatttcttc tggcgtcata ttcgtaactc
    19441 ctttcattta ctttgataac catagtataa catatttgaa tatcaaagta tagtaaaaac
    19501 tggactataa cttattagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatt
    19561 atgaagcaag taaacaacta actgatgcac gatttaagcg tcttgttagt gttcagcgta
    19621 ccacttttaa agagatgtta gctgtattaa aaacagctta tcaaaaaagt cggacaagct
    19681 ggtaaaatct tggctgacag taattatcaa gggctcatga agatatatcc tcaagcacaa
    19741 actccacgta aatccagcaa actcaagcca ctaacagttg aagataaagt ctataaccat
    19801 gcgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa aacgtttaaa
    19861 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgagt
    19921 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctat tatatatatg
    19981 cacagacata tgaaatcttt ttgatacagc cttcttttta catagagaga cagcagttat
    20041 gatatattta tccattcaca acatcttctg taccaatact acaataattg gtacattttg
    20101 attacacaat cgtttcaaaa aatatgatgg aagactgagt attttatagt aattcccttc
    20161 ctatcaacta gatcaaccag ttgagtgttg aatgttgaaa caccctagcc tcagcaaagg
    20221 actatgatca gcatttccta gccaatagga cgctccaaat cacctattct aagtccatca
    20281 ctagcttggt cagtaagata cagactgcaa ggcaagactg acgtggttga tgagattttg
    20341 gaagagtatt acaatcatag attcaccagt agacttgacc gcagatttaa ctatagtaga
    20401 ttgaaactag aatagtacac ttctgcttct aaaacattgt tagaaatcga tttgactgtc
    20461 ctgatcaatt tgtcctgttc tcgtttcatt ttactatact aaaaaaccac ctgaaacaaa
    20521 tcaagtgact agaggataaa aacaaagact gggcaaaaag ttttgaaaag caaaaaacgc
    20581 ataatatcag gtcttgaaaa accttgatac tatacgtttg attgtgggaa gattgacttc
    20641 attttctcct gaaattgaag ttttttctag tttccaggta tagacgaatt caatatagcc
    20701 atctcgctac aattatttta accatcgaaa aaatttttca gaatttcaaa aatttcattt
    20761 tgatctaatg aaatgtcatc attttgaaga atagttgact tcacaagctc taattctatc
    20821 acaaagcggt gcatgtctgc ttttaccgca ctacttgatg ttatagccga taacttttca
    20881 tctcctagca aggaagctgt caaacgggta aggtcattca aatgcttttt aatggactta
    20941 cttaaacctt gagcacctgt agcagagcgt tccctcatat ccagccaagc tttagcctta
    21001 aaaataatta atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
    21061 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
    21121 gtatagacca caattactca ataccgaata cccctgaatg gtttcttttt catgcaccaa
    21181 tatattataa taatcttcat ccaataataa ggctgataaa ctagcatctt ggtcaaaatg
    21241 taagggaatt tctcgaccgt ccttctttaa tggatattct ggtaagatac taaatagttc
    21301 aatcatagaa ggaaactcag aattagttgt tgtaaatcga aaaagctgcg ctttctcatc
    21361 tttctgactt ccttgatact ctcccaattc taaaaaatga ttcaaggtag tataaaattc
    21421 cttatttttt acttcatcaa tgatgaccat atcataatct tttgttgtgc gacttttaaa
    21481 tccttgcgaa tccaatacga tagaggtagc agttccccca atcagaacat aatagttctg
    21541 aaaatccgca aacatttctt gaaaaataac tttcgtatta gctggcatca tcttctccca
    21601 gatactgtaa tatcatattt tctagtgctt cactctcttc ctctatacgt gggtcatcat
    21661 catcttttaa ggtcaaataa agagaaatcg gatctacaaa ttgtttatca tgattatttt
    21721 taaaatcatt ccaaaactca gatacaaaag gacgatattt ccatatctct agcatctttc
    21781 attttaaaac atgctgagaa agtggcaagg ataactgatt gaattttctc tgccatatga
    21841 catagctagt attttcatcc gtttcagcta aaaaagttga atgcgacaaa gcataagcac
    21901 caccatatag aaggttagaa acagatttta tctgctttat atcgccatct ggcaataaaa
    21961 aggcaatcca cgttaattgt tcgctaggta ttaattcctt agggacttca gtatcattcg
    22021 cattcagtac tagtcccaat gtagggaaga agaggtttcc cttaaagtct acaaacggaa
    22081 ctctagcttg aagtaattgc tttttttcac cgtctgataa cttcgaaaac accaaaacaa
    22141 catccatatt ggctttatca cccatagtgc gagcctgagt aacaaatgaa ctcaaactcc
    22201 cccttctctt ttctttaatc aataaaaatg attccttatg aaaagtcatt tgagtatact
    22261 caaacttttt tacaaaactg attggtaaag tcaaagtcag ttcctcaata ctgacatcaa
    22321 cataaaagga ttgaaaaatt gacattatct ttttgacatt catgtttttt ccttattcta
    22381 tcatttttat tatattttat cattcggtat aataaaatat aagttttttg ataaaataac
    22441 caaaaactac tcgctatccc ctctcacatt accctacata tcgtttgaca tgcgactgat
    22501 agttcaggaa aacttcaagg agaacttttc tctcatccac tatgcaggac ttactatttc
    22561 acttctactc ctataggctc aatttgacat ttttcttttt cgaattgctc atatgcctcc
    22621 tgaatagtga gttcgattta tccaaattta tttttgtcta ttttgatgaa tacttccacg
    22681 aagaatgaat ttgcaccaat tttccttctc tttttaagca tattattcca gatatgattg
    22741 ccctcttgtt cagtaataaa ttacgcttta aacgcttcaa tcagtatatc tcctgttgtc
    22801 atatgttcta aagaaaattc ttctacatat ggtttaacat ctcttaggtt attacttcct
    22861 aatatcccat tatgcttttt cgctaaggaa atagatgccc cttctccttt accaataatc
    22921 ttgttactat catgatttct tgttaaatct ctatataatg cgtattcttc agttccaatg
    22981 tctatgctca caatctcagc tgaaccctta gctaccaact gatctatcct agattttaaa
    23041 tggggaattg taggtatatt gatttcatca tacacctctt gtggaataac aattttaccc
    23101 aaatagagct tttctaaaag atgttcaatg ccaacccata aaaatactga aatacaatct
    23161 gcatcaataa atacacgact agtcaaacga caactccccc ctcttcatct agcccatata
    23221 caatatcata tctgaaagca tctagtaaca gttcctcata cttcccttgc gaaattctgt
    23281 tattttctaa aagttgttca gttgaattaa tatattatcc taatgccatt tcttttttac
    23341 tttctgacaa aggacgatat aaacttgtat catagcctaa tcttgaagct gtctctataa
    23401 cactaatatc catattttta atttcttctg catcaaggta tccatcattc ctcaatctat
    23461 ataacatagc tttatgactg ataccataaa actgacccaa ttttataata tcttctactt
    23521 caagatgagt tctattggca ttttctctga tttcctcaac catcctatac agtgaagatg
    23581 ggaaaattaa aaaataagaa gcaaactgat ccgcttttct ttcagtttca tctccttcac
    23641 caatcaagat aagactgact gaactcttct tcacctcatc ataataaaga tgatacagtc
    23701 catgtgctaa agaaaatctt tacctttcta atggcatgtc tgaattgact gcaatgagac
    23761 tgaactgagt tcctttataa cagactccgc taatattctt tccgagtcca taaaatacca
    23821 gcgtcaaatt ttctatcttt tgtaccaatt taaaaatatc tatcggcgat tcaccatcag
    23881 ctcccaactt ttttctaaga tttgaagctt tattacttaa atccattcgt gatattcctt
    23941 tcaccttttt ccattttggc aatcatgctt tgattcaaag acaaatactc agcaatctta
    24001 tcttgagtaa gatttgaaga tattctaagt tcttttattc tttttccaac atcacataca
    24061 tttatcacat acatttatca tattcataca cctctcataa aaagaatagc acactcttgt
    24121 cataattttt taaataaaaa aattatgaca aaacaaggaa gcaatttatt gatgctgctt
    24181 aaaaatctaa aattgatgag ttcctatcaa aaatcgtatc ttcaacctca aaacagtact
    24241 taaagctatc cgactcggtt tacattgtca aatttagatt ttatttgagc ataactttct
    24301 agtttgcttt ctgatttttg tttaatatag tagcaaacat tgaaggaaat atctccacaa
    24361 aaaaacgcat actattaagc tttttcaaga cctaataata tgcgctgttc tgatttgaaa
    24421 gacattccat tattatttta ctgtaatcaa gccatctggc tctactgtga attctggctt
    24481 gtctgccagt gttccgtctg gtttgaggta gtaccagcct gttccgtccg ctgactggat
    24541 aaaggcattt gataccatgg cgccttcttt agcgtctaag tagtaccaag tgtccttgta
    24601 cttgacccag cctgtcttca tggcaccttc ttcgttgaaa tagtaccact tatcagcgat
    24661 tttcttccag cctgtagcca tttcgcctga gttgtcgaac cagtaccagt tgccgtctgt
    24721 gtgcttcctc cagcggtctg caagcatata gcctgaactg tcaaagtagt accaagtgcc
    24781 attgattttc tcaaacttgt cttttggata agagccgtct gaatgtacgt accagtagcc
    24841 agtgtcattc ttctgccagc ctgtttcaat cgtcaagccg ttctcaatat catacttaaa
    24901 ctgctcacgg ctaatgcccc attttgccaa gtaagggtat ggatccacat ggtctgagtg
    24961 gttgtttggt tggttattcg tgcaatactc gtgcgtttta attccagcta aactccctgt
    25021 atcaagcgtt ttcggcaaac ctgcttcatc tgctagattg cgtaagagtt cgatataaag
    25081 gcggtaatcc gtcatgaact cttctttagt tgaatggctt tcaatcagtt caaccgctgc
    25141 ataggtctca gcattccaac cgcccccaac gtcccaggca ccattatcaa caggtcctac
    25201 ctgcatgatg caaccgttcc caacaatgtg cgagaaaaaa cctaattctg ggtctttccg
    25261 ccagtgataa tccgcttcat tctgtacggt tgaatgcgga ttcccagttg agtgtgcgtg
    25321 tacttgccta tatggttgca cgccgacttg aggcaaatct gttcttaatt tactcacatt
    25381 aatttccata ttctactcct tatcaattaa aacaactcat tttttacaat ccagaaccag
    25441 aaactccttt atttctacct tacaaagaag acaatcttag tcacgattag gcttgtagat
    25501 agaacctcaa aacgcactat tttgacactg taaataggac tgacaaggtc tgcattctat
    25561 ctacaataac accccagact aaaaagcttt tcaaaagtat atttttacag tctctatatg
    25621 tccttttcat aaatactata ctttattata tcatataaaa gaagtcaaaa gtctgttaaa
    25681 ctattttcaa caccaaacta aagaagagaa cacaagtttt ttcgatgttc actagaggaa
    25741 atggatttta ttcagtaaat ccaactagga ttgcactttg gttgccaaaa ttgcctttcc
    25801 ttcttttatc aagggatgac ggaatagtga gaagtacagt tgaactgtca tggcaaccca
    25861 gataagaggt tcacaaagga taacaccctt atatcctgcc caaggaataa tcaaaaccac
    25921 aaaaacgatt tttccgatta gttcaataaa gctagaaact agaggaagga tcttctgccc
    25981 caagccctgc aagcaattgc gataaatcaa caagaggctc aaaatgggat aaaaggctga
    26041 actgatttgc agatagagac ttccattttc tatcaagtaa ccatctgtcg aactagccaa
    26101 gaaggaaacc aaggctggac tggcaaaaaa gaggaaaata caaacaaaaa ctgcccagga
    26161 tatacttaaa cgactgccga ttcgaagacc ttgaacaatg cggtcaggtc gcttagctcc
    26221 tagattctga gaagcaaagg tcgtcattga tgcagaaata gcggtcatag gaagaagggc
    26281 aaaggtcata atgcgtcgag ctgccgtctg ggcactaata atcactgcac caaatgtatt
    26341 aacagaaaac tgtaaaatca cactgccgat agatacaatt gaactcatca agcccatagc
    26401 caaaccttgc tccaagagat ccgcgtacaa gcttttgtcc catttgaaat gtttaaaccg
    26461 tggcaagagt tctggcacac ttttacgaat ataataaaag cagagaaccg ctgataaacc
    26521 ttgcgaaata atggtagcaa gtcctgcgga ttgaactccc agatgcaatt gcgtaataaa
    26581 atagagatcc agaaccacat taaccaaggc agagaaaatc agaaatccca gggctgctag
    26641 actgtcacca atagaccgca acaagcctgc aaaaagatta taagcaaagc tgacacctac
    26701 acaggtcaca atcatagaaa tatattgata agattgagga agaatttctg caggagtatc
    26761 taagtattgc aagagaggat acaagccaag aaagcccagc aacataacta gaatgctcaa
    26821 aagagcacct aaaatccagg tggctgctac tgcttccttg attttagtga aattccgagc
    26881 cccataataa cgagcaatga caatccccat gccattgcca acaccaagtg taaaacctac
    26941 aatcaggtca aaaatcgctg tcgtcgctcc tactgcagcc aaggattctt gaccaagaaa
    27001 tcgtccaaca atcaagacat cagcagtgtt atagagctgt tgaaaaatat ttgatagcaa
    27061 gattggaaag gtgaagctta agagcgaggg aagaatcgaa ccatgtatca ggtccactgt
    27121 tcgtttttta ttcataaagc tattatatca gctttccaga ggagcgacaa gaaacagcaa
    27181 acttatatat agcggaatga aataaggaca gtcaaatcga tttttaacaa tgttttagaa
    27241 atagatgtgt actattctag tttcgatcta ttatagttgg ttgagtttgg aatagtacgc
    27301 tgtagctgct aaaacatttc tagaaattaa tttgactttc ctaataaagt tgttcatatc
    27361 ttatttcaag ctactatata taatctaaaa acttgaatca aaaatcgaaa aagtagcgga
    27421 tttttccact gctttaacag cttattcttc aatttcgatt tcaagttcat cgcctaagtc
    27481 aagcgtaact tcttcattca ctgcttcttc tttctttggc tcatcttttt tgttttcagt
    27541 atcttgttct gaaacttctt ctccatcaat caagccaaat ttagaacgga cttgcttatc
    27601 aatttcatca aagatttctg ggtgctctgc caagtatttc ttagcattct cagaaccttg
    27661 cccaattttt tcatctttgt aagaatacca agcccctgct tttttgataa tatccaaatc
    27721 gcttgcaatc ttcaaaagct caccagtctt agaaattcct tctccgtaca taatttcaac
    27781 tacggcttcc ttaaacggtg gagctacctt attttttaca accttaatct tagtttcttt
    27841 accgacattg gtttcttttt ggtcaccagt tcccttaatt tgtgtattac cacgaacatc
    27901 caagcggact gaagcataga atttcaaagc acgtccgccc ggtgttgttt ctggatttcc
    27961 aaacatcact ccaacttttt cacgcaattg gttgataaaa atggcaattg ttttggtttt
    28021 attgatagag gcgccaagtt tacgcatggc ctggctcatc atacgagcct gcaaaccaac
    28081 atggctatct ccgatatctc catcaatttc cgcacgagga acaagggcag caactgagtc
    28141 gactacgaca agatcaactg cacctgagtc aatcaatttt cccgcaattt caagaccttg
    28201 ctctcctgag tctggttgag acaagagcaa ttcgtcaata ttgacaccaa gggccgcagc
    28261 ataagctgga tcaagggcat gttccgcatc gataaaggca gcaatcccac cttctttttg
    28321 cgcttgtgca actgcatgaa gggcaaccgt tgtcttacca gatgactctg ggccatagat
    28381 ttcgatgata cgtcccttag gataaccacc tgagccaagg gcaatgtcaa gagctaaaga
    28441 acctgagctc atcacttgca ccttttgctc cgcacgttca cccaaacgca tgattgatcc
    28501 tttaccaaag tctttctcaa tcaatttaag agcgtcattc aaggcctttt cacgttctgc
    28561 cccaaatttt tttgaaattt cttctaattt ttttggtttt ttcgccattc tattctccta
    28621 cattctaatg atcctcagac ctatctacta ttatatcaaa agttagtcac ttaataaagc
    28681 cttgcgaact aggttaaagg catgcataac cgcaatatga cgtacatctg ctcggcttct
    28741 gcctccaata ttaaccttga taacctcagt tccttgctct tgcgccaagc ctatgaagac
    28801 tgtcccaact gggtgtcctt ctaggctatc tggtcctgcc actccggtca aactaattcc
    28861 aaaatcagac tgggtcttgc ttcgtgcctg ctcagccatc ttctgagctg taaattcaga
    28921 caccacacca tgttcttcca aattcttggc aggaatatcc aacatccttg atttttcctc
    28981 caagctatag gtcacaaaac cacccttaaa tatacttgaa actccagaaa aattcgccac
    29041 ggtagcttgg aaaagacctg ccgtcaaact ctctgcagcc gcgatggttt tcccttgcct
    29101 tttcagttct tctaccacaa tgctggctaa actagtttct tccccataac catagcaaaa
    29161 gtctcgtaaa gaaattcctt cgaaagtctg gcagtccaag atttgatttt ccaagatatc
    29221 cagcgcttga ttcgcctctt cttgactgct agcctttgtt gacagacgta gagtgacttc
    29281 tcctgtcttg gcataagggg ccaaggtagg atcgatctga ttatcaatta aatcagccaa
    29341 aatcgtaacc agctggctct cgccaatccc aaagaaacga agaactcggg aatacagctt
    29401 gctccctgtc atcaacttgg gtagaagttg gtttaagacc atgggtttca attcacttgg
    29461 cggacctgga aggacgacat aggtcactcc gtctacttct aattttcctc caacagccag
    29521 tcctgtttcg tttggcagtg gaatcgctcc ttctacaatt tgagcttgtc tttcgttatt
    29581 cggtgttcgg gcatagtctg gtcgcagggc aaaaaagata tccaacttct cctgagcctg
    29641 aggatcaaag actaatgctt tccctaaaaa tttagctagg gtttgtttgg ttaggtcgtc
    29701 ctcagttggc cccaaaccgc ctgtcaaaat caccagactg ctacgttgac tggcaatctc
    29761 aagcaaagac aagagacgaa cttcattgtc tcctacagcc gtctgaaaat atacatctac
    29821 cccaatctca gctagttttt ccgacaaaaa ctgggcattg gtgttgacaa tctgtcctgt
    29881 caaaatctct gttccaacag caatgatttc tgctttcatg tttcctccta cctatctatt
    29941 cgtatttttt tgaaaaaatc gcaggaattt tcctacgatt gattttttta tttgtatcaa
    30001 aagttaatta tcttcatcac caacaggtgc tctgccaaat aaatcttcaa ataaaaccgc
    30061 attggtttca agctgagtaa cttcttcttg tcccaaagaa cgtcggagta tattttgcat
    30121 ttccaacata tgtgctctcg aaacaatctg gtaagaaaca ccttgaagta tctctccttc
    30181 accctgcaac tgctgagttt caatggtttt aaatgaatct ttatagccta gcaagttagg
    30241 gatacttttt gcagacaaat caatattggt ctgcatattg tcactcaaag cttttagaat
    30301 ctcttgataa tgaccaatgc tatttaaact gagagctttt tccatgactt tttgaataac
    30361 ttcacgttga cgtttttgac gaccataatc cccctcagga tcttggtaac gcattcgtgc
    30421 atagactagg gcttcttctc ccccaatatg ttgctcccca acaccgatag aaatggtatt
    30481 aaattcttct tggtcactga tagaaattgg gaaacctagg atattattga ctgtaatacc
    30541 tcctactgca tccactaatt tttgcaaccc tctcatattg accatcacat agcgatcaat
    30601 atggatattc atcatttttt gaatggtttc tatagcaagc tctgctccac catctgcata
    30661 tgctgagttc agtttcgctt catgagcctg accattccct gattcaatgc gcgtcagaat
    30721 atcccgctct aaactcatca ttgttgtttt tttcgtttta ggattcactg tcatcaagat
    30781 catgctatca cttctaccga cccaagtttc agttcgttca acatttccgg tgtccactcc
    30841 cattaacaga atggttagag gttcagtcgc ttcaataacc ttggtttctt cgccgatttt
    30901 tttataggtt ttagctaagg tttctgtccc ttgttgataa atagtataag caaaaacacc
    30961 tactcctact acagttacag aaagtaaagc tagcaccatt ccaataattt ttttaaccat
    31021 atttctacta acctatcagt ttacccatca agtaaacatc gataaatttc ccttcttcta
    31081 tatatgcccc acgctcttgg ctaccttcaa tgacaaagcc atgcttttga taaagatgga
    31141 ctgctgcttg attacgagtt tggacagtca gttggagacg acgcagaatg ccacttgctt
    31201 gtgcccactc tatcgcttct tctagcaaca aacttcccaa gccattattc caatatcttt
    31261 ttccaatcac aatgaagaga tctccaatat gacggactct cttacgctga tcagctgtaa
    31321 tatttacaat accagtaatt ttgccattta agaatgcaag taaggttatc tgattgtccg
    31381 aactagcttg cttgttgagg aatatttcca tctcctcact agtcaagaga ataccatctc
    31441 cgtctaggct ggtaaagtct gtctccaaac tcacacgatt taaaaaggcc actaattcag
    31501 ctgcatcttt gggctctgct tccctaatga gcaattcata ctccatattg aagctcctct
    31561 gacaatttct cagcacgcaa accctttgcc tgaaaattta aacggcgtcc atctgcttct
    31621 tttagaattt ccaattctaa ataagcatct ggcaaggcat ctcctaagag atttccccac
    31681 tcaataacag tcacgccgcc accaaagata aactcatcca agtcgataga atcagcatct
    31741 ccttcaatac gataaacatc taggtgataa agtggaagtc gaccttcata ctctctcacg
    31801 atagtatagg taggactttt aatcatttga gaaatctgta atccttttgc aagtccttta
    31861 gtaaaggtcg ttttacctgc acccagttct ccaattaaga ttaaaacatc attctttgct
    31921 aatagatggc ccaaacgctc ccctaaggct tgcaactctt cttcattttt tatgtacata
    31981 ctcttattat accaaaaact tttcttttgt gtctattttc ctactaaact tatcatcata
    32041 acatccataa aaaacaggct ttctctaaaa gaaaatgagc gtaacaatga ccaatacaag
    32101 atctcggaaa atatgaccat aaaaggaaac ttccttctta accgaatttg ggacaagata
    32161 ggctgcaaaa aacaagccca gtccaatata aatcagaagt gagacaatgg tcattggatt
    32221 tcttaagaaa agaagtgttg ctaaaatagt caccaacact gtcttttttc tgtccagcat
    32281 agcaagaaaa tcgcgcacgt attttttcaa gggtaaaaaa atcagcaaat ctagcccaaa
    32341 taggaaaaag aaggatggca ataaaaagtc aactaattct tgctgcagcg tatttttgat
    32401 gaacaagtta tctgacaaaa caagaacagc tcctaacaaa ttaattaaga gtaacatact
    32461 gtaaaaaagc ttcaccgact tcttactggc taggacacta tggacttctt gcttacgagt
    32521 ataaagataa tttactccag cacagattcc tgaaacgaaa accatgcttc cgatgaaaaa
    32581 agctgtactt tgtttaaagg acaagatgca ttccttccat aggaaacagc tactcaaact
    32641 gatttgaatt aaagctaaca aaaataagat tctcattgat ttcatcttct ctctcccttc
    32701 ctaccaatca ttatactagg agaaaagaga gaactgtttc taatcttctc aaatgtctct
    32761 ttaagacgct aaacaaacac tagagactaa tactcaatga aaatcaaaga gcaaactagg
    32821 tagctagcca caggttgctc aaaacactgt tttgagattg cagatagagc tgacgtggtt
    32881 tgaagagatt tacgaagaat ataaatttga aatcatgaaa atccgtcaaa cgggtggttg
    32941 ttttgtctcg cacctcacgg agcgagacgg actcagagtc acataattat aaggctgata
    33001 gtattaatct aactatcagc cttacaggtt atttaacgtt tcagaaaaac tataatgtca
    33061 agattaacta aacagtatct agttccttca aataattttc tatcttcatc aacattaaag
    33121 gattgttata aatcttacat aactctcttg cttctatata ataatttttg acttgttctc
    33181 tgtctagaaa tttggctcca gcatttccta caagaataag tagaggagcc aattggtagc
    33241 ttgtctgtct ttgtttacag agttcaatcg tttcaagagc ttcttggatg gcttcattat
    33301 atttttcctt tgatactagg tagtgagcgt agttgtaacg aactctgatg tagccaaata
    33361 aaaactcttg atggtccaaa ttttttgtct gatacaactc tattaaatga gagtagtttg
    33421 cctcatattc ttgttcacga cccactaagg aatagaaatt agatagagta ttcaacgcct
    33481 ttaaataaat cagagtattt gaagagactt ttaataatat attttccaat gaagaaattg
    33541 cctcacactt actgtcatat tgatagaagt caataatagc tttaatccat tcaaggtaag
    33601 ttcggtcttc tagtgttaga aaagtacttc gttcaatctc tattctataa atatattcca
    33661 aatcgtcata atttctatcg tctaatagtc gagcagacaa ttgcttgaaa ttagagaggt
    33721 tagatttaat ttcaatttgt tcattaaaaa aataatctaa tggtacttca agtcgttgag
    33781 agagtttgaa caaaaggtct gcggagggaa tgaaatgccc tctctcaatt ttactaatct
    33841 gactttgttc acaaattcct tctgcaagag tttgttggga gagtctcaac tcttttcttt
    33901 tcaatctgaa tttctctgcg agtgtattca ttaaagataa taaaccttcc tatttgctta
    33961 attgcattat aaaattttta gttcaaaata gcaagttaaa agaataaata attctttatg
    34021 gtaataaact aaaaaaagtc aaaaattaca taaaaatgct tgaccgaata atatatatat
    34081 attaaaataa aaacaaggaa aaagaaaagg gtttcacgaa tgaagaaaaa tcgtggaatt
    34141 caaaaattag ctatattagt attactaggt gtttttatgc ttagtaacac aattccttac
    34201 caacagttta ttcagaagaa tagacaattg gagattcgag tccaatcaca aaagaagtcc
    34261 aatggtcttg atgttgggaa ggctgattga tttcgtatta ctttaaaatt caactattta
    34321 gagaaaggta ttctgatgag agcttgtaac aataccagat agatattagt aagcttgtta
    34381 gtttatagag ggcaggggta tttctgccct ctgttttaga ataaggaatg cactatgaaa
    34441 aaattattta tactcatatc caacctgctt gctagtttgt tctttgtttg ggtatttacc
    34501 atttggactg atacatatgt ctcctattat taccccaacg ttgttgtaca tgattcttcc
    34561 cctgaaacaa cttttcagca tgttgctaca cgcttggaaa aactagcaga agaaacagat
    34621 agctttattg cgattcaaca ccaagattct aactcagaag gtactacagt tttttcttat
    34681 acgacctttg gggacggaaa gttgcctgat gggcttcagg aaaaaaaact agaagatgct
    34741 caaagtagta gtgttgaaac aaactatttt gtattcgatg gacacctaga tattcacttg
    34801 ctaagggagg agctaagtca acttggcttg actaacatga acctgacaat tccatctaaa
    34861 ctatctacgt taatggctat ctttagtaac ggatttcagt taatcagtct attgattttc
    34921 atcttaacct ttgtagcact gactttaatt agtcaaatta gccaattacg gtcgtcgggc
    34981 attcgcctca tttcaggaga gaaacggtgg tccattttcc ttagaccagt tggtgaggat
    35041 ttgaaaggga tagctgttgg tttcagttta gctggcgtgc tcgccattct tatgcaaaaa
    35101 attctgtcgc ttccaacgca atccctaatg accataggag caggcttgct cagttataat
    35161 ctcatcttgt tgtcgatctc cctgtttttc gctcaactct tcgcagttgg gataaaaaag
    35221 atacacctga tgcagattat aaaagggcaa gtgcctgtca gaggaatcat tagtttgatt
    35281 ttaatcggtc aactattagc gattattatt gtaacgctgg gaatagggag tagcttaaag
    35341 tattcccaag cctggcaaca gcatcggatt ggacaagagg cttggagtca ggaaaggcaa
    35401 ctgattaccc tatcaatcag ccgtgaagga acgagtcctg gttttgatga acaagctcaa
    35461 aggaaactca gaacttggta tcaattgatg gatctggctg tttcagaaca aaaggctttc
    35521 ttatctagac accagttaat tgaccgtact ttgcaaaatg gcatggcttc ctccaaaaac
    35581 ttgataacct ctacagaatg gcacgattac aacccgaatg gcaatgtcct tatcgtcaca
    35641 ccgcaatact tggagcgtca aaacattcct gtagatacaa ctattgagca aaagatgaat
    35701 cacctttatg taggggagtt tgtcttattg ctgcctgaac acctccgttc agaggaagaa
    35761 cattataaat ctgtttttga agacgactta accagtcgca tgtctagtca agatgaacga
    35821 cagcaaatga ctgctacggt aggttattta gaatcaggtc aggatcgttt tgtgtataat
    35881 acgaccccta tttcttacca gcagtttttg aaagatccaa tcatcattgt tataacaccc
    35941 caatcaactg gtccacagtc cattttgttt tggatagacg cagtacagaa ctacgttctc
    36001 tttaatcaat tgtctgatgc ccaggagctt atccagagac aaggcattga aaattgggtc
    36061 tcagaaatgc aaacaggtta ccacaactac atcacattat tggataatat tcagagggaa
    36121 cgttgggtaa tgctagcagg agctgggctt gggattgcaa cttcaatctt gttgtttaac
    36181 actatgaata ggctctactt tgaagaattt agacgtgcca tttttatcaa acgcattgca
    36241 ggtctcaggt tcttagaaat ccatcgcact tatctctttg ctcaactggg tgtgttttta
    36301 ctgggatttg ttgcgagtgt atttcttcag gtagagatag gagttgcttt cttagtcttg
    36361 ttactcttta ctggtctatc tcttttacag ttacatgtcc aaatgcagaa agaaaacaag
    36421 atgtccatgc ttgttttgaa gggaggttaa tatgattgaa cttaaacagg tgagtaaatc
    36481 ttttggagaa cgagagttat tttcgaatct ttcaatgaca tttgaggctg gaaaagtcta
    36541 tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg atgaacatga ttgggaaatt
    36601 agaaccttat gatgggacga ttttttaccg aggtaaagac ttggccaatt ataaatcgag
    36661 tgattttttc cgtcacgaat tgggctacct cttccagaac tttggcttaa ttgaaaacca
    36721 aagtattgaa gaaaacctta agctaggtct cattggtcaa aagttgagtc ggtcggaaca
    36781 gcggttgagg cagaagcagg ctttagaaca ggtcggcctg acttatcttg acctagataa
    36841 gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt gccttggcaa aagttatctt
    36901 aaagaatcca ccctttattc tggcagatga gccaacagct tcaatagacc cagcaacttc
    36961 tcagttgatt atggagattt tgctatctct tcgagatgat aataggctaa tcattatcgc
    37021 aacacataat ccagcaattt gggagatggc tgatgaagtg ttcacgatgg atcgtctgaa
    37081 ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa atattatcat gaatcaataa
    37141 ttggagttaa tttagaattg tactttatta atattgaggt aactttttct tgataaagga
    37201 agaaatagtg gagaggaagt tagaatgaaa aaattcgaca attatattgt tgagaagcct
    37261 tgcgattcta attcagataa actgcaaaaa atcttaataa ttgaaaattt ggtagatgat
    37321 attttgcaat ttcctctcag aatcaataat agtgtaggag agattttcct cctacaaccg
    37381 tttcaaaaga aaactatctt tattccatgt tattttgagg aagatattgt gaaagtcaaa
    37441 gatgatgata aagttgagtg gaatttgtta gaatttcaaa aatttagagc atttttggct
    37501 tagtaatctg tgttgaaggc tcaaaaccta tggtaaaaaa gtcgctttga aaacgtattg
    37561 cctccaaaga tttagttaaa taatgattta acacaaaaag aaattattga agttctggaa
    37621 agatgttgtt tcagtattga gaaaaggtgg gaaaaacttg cgattttcac agagaaagga
    37681 agaaaaagta tagaaatata gtcaattgaa acaagaacag gacaaaagaa ccttttgtgc
    37741 catatttttc tcctttcgct ttacaattgg cttgaacacc tttattgtat cgcgtttgga
    37801 gtttttttgg tataaccttc gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc
    37861 taacggagcg agacgaacta atagtcactt aatcaaaaaa cgcaccatat caaaaactaa
    37921 aaagtttgat atcatgcgtc atgtcttaaa ctaattgact atactttcta ttcaaatgag
    37981 cttttaacca attgattgag ccaatccact cttaaaacca aagagcaatt tctcgcttag
    38041 ctgactcttc tgaatctgaa ccatgtacaa cattttggat aacctcattt tctccagcag
    38101 cttttgcaaa atcacctcga atagtgcctg gtaaagcttc ttctggacga gttgcaccca
    38161 tcatggtccg ccaagtttcg attactttgg gaccagaaat gacacccaca agaactggac
    38221 ctgaagtcat gaattcacga atcggtgggt aaaaactctg accaaccaag tcctgatagt
    38281 gctggtcaat caactcttct gaaacttgtg aacgaaactc caatttttcg attgtaaatc
    38341 cacgttgttc gatgcgcttt aacacttcac ccactagccc tctttttaca ccatctggtt
    38401 tgatgataaa gaatgtttgt tccatacccg tctcctttgt cagcttcttt cttttatttt
    38461 accacatttc gtggaaaaat ggagaaagtt ttcagaatag agaatgagag aacccgaggg
    38521 ttctctcatt ctctattatt ctactgtttc ttccacagtt tcaacggcag tatccacaac
    38581 tacttctgtt gtttcttcat ttccttcttc ctctactgga ggattaaggt attcttcttc
    38641 gttgacagca tatggttcaa ggttacggta acgggccata ccagtaccag ctgggatgat
    38701 cttaccgatg ataacatttt ctttaagtcc aaggagatgg tctttcttac cacggatagc
    38761 tgcgtcagta aggacacgag ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt
    38821 ttcaagtgag gctttggtaa ttcccataag gactgggcga cctgtcgctg gaactccacc
    38881 tgcgataagg acatctttgt tggcatctgt aaagtcattg atatccatga gggtacccat
    38941 gagaagatct gtatcacctg gatccatgac acggacttta cggatcattt gacgaaccat
    39001 tacctcgatg tgtttgtcac cgatttctac cccttggcta cggtaaactt tttgtacttc
    39061 accgagaagg tacgtttcaa ctgacaagac atcacgaact gcaaggagac gttttggttg
    39121 gatagaacct tctgtcagag cagcaccacg cgctacttgg cccccaactt cgacacgcat
    39181 acgagctgta aatggaacga catattcacc ttcgccagtt tcacccttaa caaagacttt
    39241 cttggtacga gttgatgcat cttcttcgat agcagtaact tgtcctttaa cctctgtgat
    39301 aaccgcttcc cctttaggat tgcgggcttc aaagatttct tggacacgag gaagaccctg
    39361 agtgatatcg gtatttgagg caaccccacc tgtgtggaag gtacgcattg taagctgtgt
    39421 accaggttcc ccgatagatt gggcagcaat ggtaccaact gcttcaccaa cttcaaccgc
    39481 atcaccagtc gccaagttga taccgtaaca gtgacggcag acaccgtgac gagtgttaca
    39541 tgtaaataca gaacggatag tcacttcttc cacaccagca ttgacaattt cacgcgcctt
    39601 gtcttctgta atcaattcat ttggaccaat aatcactgca ccagtttctg gatgtttaac
    39661 agttttctta gtgtaacgac cgttgagacg ctcttcgaga gactcgatca tctcttttcc
    39721 ttctgcgata gaacggatca agagaccacg gtcagttcca cagtcgtcct cacggatgat
    39781 aacgtcttgg gcaacgtcga ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag
    39841 ggccgtatcg gtcatacctt tacgagcacc gtgagttgag aagaacattt ccaataccga
    39901 caaaccttcg cggaagtttg aaaggattgg caattccatg atacgtccat tcggagcagc
    39961 catcagacca cgcataccgg caagctgtga gaagtttgag atgttaccac gggctccaga
    40021 gtccatcatc ataacgattg ggttcttagg atcttggtta gcaatcaagc gtttctcaag
    40081 tttttcacgg gcagcacgcc attcagctgt aacagcattg taacgctcgt cgtctgtgat
    40141 cataccacga cggaattgtt tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat
    40201 ttcagtcttg tcatcaacga ctgggatatc ggcaataccc actgtcaatc ctgcaagagt
    40261 tgagtggtgg taaccgaggt tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg
    40321 gaaacgtttg aagatttcag cgatgatatt tccaaggttt ttcttcttga atggagggtt
    40381 gagctcaaga ttgctgatag cttccttgat atctccacca agtggcaaga agtatttagc
    40441 tggaacacct tctgtcaagt tggcattgtt tggttcttgc aagtatggta gcccctctgg
    40501 catgatatcg ttgaagagaa ttttaccaac tgttgtaagc aagaccttat gtctttgctc
    40561 ttctgtccaa ggcttgttga ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac
    40621 ataaccattg cggtaagcca taaccgcttc gtcacggtct ttgaagacca ttccttcacc
    40681 ttcgcgacca gcttcttcca tggtcaagta gtagttaccc aaaaccatgt cctgagatgg
    40741 agtaactacc ggtttcccat ctttcgggtt caagatgtgc tcagcagcta gcatgaggat
    40801 acgagcttct gcttgtgctt cttctgaaag tggtacgtgg atggccattt ggtccccgtc
    40861 aaagtcggca ttgtaggctt cacagacaag tgggtgcaag cgaagagcct taccatcaat
    40921 taagactggc tcgaaggctt ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag
    40981 cactgggtgt tctttaatca cttcttcaag gatatcccag atacgctcat ctccgcgttc
    41041 caccaagcgt ttagctgctt tgacgttttg cacgatatca cgggcaacga tttcacgcat
    41101 gacaaatggt ttaaagagtt caatcgccat ttcacgtggc acaccacatt ggtacatctt
    41161 aagagttgga ccaacggcga taacggaacg tcctgagaag tcaacacgtt taccgagcaa
    41221 gttttgacgg aagcgtcctt gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg
    41281 gctacctggt cctgtgattg gacgaccacg acgaccattg tcaatcaaag cgtcaactgc
    41341 ttcttgaagc atacgtttct cattttgaac gatgatacct ggtgcattta actcaagcaa
    41401 acgagccaaa cggttgttac ggttgataac acggcggtaa aggtcattca agtcagatga
    41461 ggcaaaacgg ccaccatcca actgcaacat tggacgaaga tctggtggga taaccggaag
    41521 gatgttaaga atcatccatt caggtttgtt tccagacttg taaaaggcat ccaaaacatc
    41581 caaacgacgg atggctttga cacgtttttg tccagtagct gttttcaatt cttctttgag
    41641 ttcagcaatt tctttttcaa gatctacttg cttcaaaagg tcttggatgg cttccgcacc
    41701 catcttggca acaaatgaac cataaccata ttcgcgcaag cgctctcggt attcgcgctc
    41761 tgtcatgata gacttgtgct caagtggtgt atccttagga tcaatcacca cataagccgc
    41821 aaagtagata acttcctcga gggcacgagg gctcatatca agggtcaagc ccatacggct
    41881 tggaatcccc ttgaagtacc agatgtgaga tacaggagct ttcaattcga tatgtcccat
    41941 acgctcacga cgaactttcg tacgcgttac ttcaacccca cagcggtcac aaacaattcc
    42001 tctgtaacga atgcgtttgt acttaccaca agcacattcc cagtcttttg taggaccaaa
    42061 gatcacttca tcaaagagtc cttcacgttc tggtttcaag gtacgataat tgattgtttc
    42121 aggttttttg acttctccat aagaccatga acggacttta cttggagaag ctagggtgat
    42181 ttgcatactt ttaaaacgat ttacatcaac cactatttct tccctttcta ttctaagtga
    42241 actgcttatt cttgttcagc agcttcttct gttgcttccg cttttgttgc tttctcagct
    42301 tcttcagctt caaaggctgc tttagcctct tgggctgctt tttcgcgggc tttttcaagg
    42361 tcatctacgt ggatgacatc ttcgtccatt ccttcatcca agtcgcgaag ttccacttct
    42421 tggtcatctt cgtctaggac acgcatgtca agaccaagag attgcaattc tttgacaaga
    42481 actcggaagg attctggaac acctggtttt ggaattggtt tgccttttgt aatagcttca
    42541 taggctttca aacgtccgtt gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca
    42601 tttgacgcac cgtaggcttc aagagcccaa acctccatct caccgaaacg ttgtccacca
    42661 aactgagcct tacctccgag tggttgttgg gtaacagttg agtatggtcc gactgaacgc
    42721 gcgtgcaatt tatcatcaac catgtggtgg agtttgatca tgtacatgac tccgacagaa
    42781 acacggttat caaacggttc accagtacgt ccatcgtaaa ggatcgtttt ggcatcgcta
    42841 tccatacctg cttctttaac agttgaccaa agatcttcag aacttgctcc atcaaagact
    42901 ggtgtcgcga tgtgaatacc aagagtacga gctgccatac caaggtgaag ctccataacc
    42961 tgaccgatat tcatacgtga tggtacccca agtgggttca acatgatgtc gactggagtt
    43021 ccgtctggaa ggtaaggcat gtcttctaca ggaacgatac gagagacaac ccctttgttt
    43081 ccgtgacgtc cggccatttt atctccgacc ttaatcttac gtttttgagc gatgtaaaca
    43141 cgaaccaaca tgttaacacc tgattgcaac tcatctccat ttacacgtgt aaagatctta
    43201 acatcacgaa cgacaccatc ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca
    43261 cgagacttgt ctccaaagat agcgtgcaag agacgttctt cagctgaaag atctttctca
    43321 cccttaggtg ttactttacc tacaagaata tcaccttctt taacctcagc accaatacgg
    43381 ataatcccca tttcgtcaag gtctttgagg gcatcttcac caacgtttgg aatttcgcga
    43441 gtgatttctt caggcccaag ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga
    43501 acagatgtgt agacatcgtc cttcaccaag cgttcgctca tgataacggc atcctcgaag
    43561 ttgtaacctt cccaagtcat gtaggcaacg attgggtttt gtccaagcgc catttctcca
    43621 ttttccatag aaggtccgtc agcgatgaaa tcgccttttt caacgacatc accaactttt
    43681 acgagagtgc gttggttgta agcagtacct gagtttgaac gacggaattt ttggatgtgg
    43741 taaacatcca atgaaccatc ttcacgacga acttctacct tgtcagcatc tgcgtaagta
    43801 actttaccat catactgagc aatcacagcc gcaccagaat cgtgggctgc ttggtattcc
    43861 ataccagtac caacgtaagg tgcctgagga ttaatcaatg gcacagcctg acgttgcata
    43921 ttggctccca tgagggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc
    43981 gcaacggcaa ctacctgttt tggtgaaacg tccatgtagt caacaatatt agctggatac
    44041 tcttggttga ccccttggtg acgtcccatg acaatcttct cagcaaaggt tccatcttca
    44101 ttcagacgag agttagcctg agctacagta tattcatctt cttcatcagc tgtcaaccaa
    44161 acaatttcgt tcgtgacaac acctgtttca cggtcaacct tacggtatgg tgtttgaaca
    44221 aaaccatatt tgttcaagtg tccgtaagat gacaagttat tgatcaaacc gatgttaggt
    44281 ccttcaggtg tctcgattgg acacatacga ccatagtgag tgtagtgcac gtcacgtact
    44341 tcatatccgg cacggtcacg agtcaaacca ccaggtccta aggctgacaa acggcgtttg
    44401 tgagacaact cagaaagcgg gttgtgttgg tccatgaact gtgacaactg tgatgaacca
    44461 aagaattctt taactgcagc tgttacagga cggatattga taatttgttg tggtgtcaag
    44521 acttcattgt cctgaacaga catacgttca cggacattac gttccatacg agaaagtccc
    44581 aaacgtactt ggttggcaag caattcacca accgcacgga tacgacgatt tccaaggtgg
    44641 tcgatatcat ctacacggcc aagtccttca gccaagttga ggaagtagct catctcagca
    44701 aggatatctg caggagtcac cgtacgaacc ttgtcatctg ggttagcatt accaatgatc
    44761 gttacgacgc gatctggatc agttggagca acaaccttga atttttgaag aacaacaggc
    44821 tcagtcacaa cggctgcatc gtttgggatg tagacaatct tgttcaagtc gccatccaaa
    44881 tggctttcaa tgctttcaat cacgctacga gtcataatcg taccagcttc taccaagatt
    44941 tctccagttt cagggtctac caatggctct gcaatggttt ggttgagcaa acgtgtttta
    45001 acattgagtt ttttattgat tttgtaacga ccaactgctg ccaagtcata gcgacgtggg
    45061 tcaaagaagc gagccacaag caagctacgt gagctttcag ccgtcttagg ctcacctgga
    45121 cgaaggcgtt cgtaaatttc tttcaaggct tcgtctgtac gagagtccat tggattcttg
    45181 tggatatctt tttcaacagt gttgcgaacc aattcgctgt caccaaaaat atcaaagatt
    45241 tcatcatcac ctgagaaacc aagagcacga accaaggttg taaatggaat cttacgagta
    45301 cggtcgatac gagtgtaggt gatatctttt gagtcgcttt caagttccaa ccaagctcca
    45361 cggttaggga taacagttga accatagccc accttaccat ttttgtctac tttgtcgtta
    45421 aagtaaacac ctggtgagcg gaccaactga gaaacgataa tacgttcacc accattgatg
    45481 atgaaagtac ccatttctgt catgattggg aaatcaccaa agaaaacttc ttgggtcttg
    45541 atttcgcctg tttctttatt gatcaagcgg aaggttacaa aaattggtgc tgagtagcta
    45601 gcatcgtgaa tacgagcttc ttctagcgtg tattttggtt ccttgatttc atatccaaca
    45661 aattccaact ccattgtgtc tgtgaagttt gaaattggca atacatcttc aaacacttcc
    45721 ttaagaccgt ggtctaggaa agctttgaat gagtcagttt gaatttcaat caaatttggt
    45781 aagtcaagaa cttctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga
    45841 acgtcatgtc ctgccaagat gattctcctt tgtaaataag ttccaagcct tgtcaatcag
    45901 gcttttctaa tcgccatatg gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt
    45961 cagaatcttt aagcctctgt tacaaatgct caaaatcttg aaaaaaagca caaaaagagc
    46021 agctaaatct gactttttca gaagatttaa ctgctgtgag ccttgtctgg acaatatttc
    46081 agacaaaacc tacgacaaat gattacccat attataccct atttagctag atttttcaag
    46141 gggattcagt aggtttttgg taattttttt cccatagaaa acctggcatc acattcgaat
    46201 cacgctatgg tacaaaaaac tgaaaaaact attgactgaa aatcattttc aaggtataat
    46261 aataaacgtt aaggcggtat agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt
    46321 cggttcaaat ccgtctaccg ccttctataa cttgatttat caggtttcaa atgaacagaa
    46381 agcccaattt gaagggcttt ttttattttc cctcgaataa atacgtataa ctttaaaaac
    46441 ttttggagcg agtttgtggc agagttcttt ccatggcata attccctttt gaaatcaatt
    46501 gaaaaaagct tcgtcacgcc tggtgacaaa agcctctagt ttattctgtt tcttcttcta
    46561 tttcgacttc tgtgatttgg acttttacct tggtaacacg tccattcttc actttatcat
    46621 tggttaagat aaactgtttg ttttggctga ccaattcata gctgagtttc tcagtcgttg
    46681 gaatggttcc cactcctgtc aaataataac cagcgatggt atcaacgtca tcactttcca
    46741 gttcaacatc aaagtaatta ttgaaatcat tgagggtcat agttccttga acaatgtagg
    46801 tatcctcgcc aatctgatga acatctattg ctgctttgtc cgtttcatca tcaatttcac
    46861 caacaatttc ctctaagagg tcttccaaag tcaccaaacc agccatacca ccgtattcat
    46921 ccagcaagat tgccatttgt ctttgggtat ttcgcagttc ttttagcaag tcatccacaa
    46981 aaatagtttc aggtacaaaa agtggatctt gtaaaattct cttccaaaca atattgtcaa
    47041 aaccgtccac aaagcctgcc ttaaggagac tcttggtgtg aatgattcca attacattgt
    47101 ccttatcccc atcataaacc gggatacgag aataattttg ttttaaaata ctttggataa
    47161 tggcttgact atcatcctga atatccacca taaaggcatc cgttcgaggc accataacct
    47221 ctcgtgccat cagttcatcg agcgaaaaga caccttgtag catctcaatc tcatcagcat
    47281 ccaatgtttc ttcactattt gtcagcatat aggcaatttc atcacgggtc atcttttcat
    47341 ccgcatcatc gaatgacata ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa
    47401 gccaaacaaa aggactgact agttttccga tcccaatgat aatcggcgct gtacgaattg
    47461 ccaaggcatc ctttagatta agagcgattc tcttaggata taattcccca aaaacgatgg
    47521 aaatataggt caaaaatgcc aaggatagaa aagttgccac ggcttgtgct gtttcgccat
    47581 tcccaagcca agaggcaatc acacgtccta gagtatcagt taaactcgcc cctgataaga
    47641 ttgtaatcag ggtgattcct acctgaatgg ttgataaaaa gtggttagga ttttctagta
    47701 ccttcagcag gcggatgtag cgtctgtctc cttcttccgc cttttgttca actcgggcac
    47761 gattaagaga aaccatggcc atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga
    47821 taaacaataa aacaaattgt agcaacaaat tctgactact tgggtcttcc atagttcttc
    47881 tcctaaaata gtatcttatc ctttattata tcacaaaatt taatccaata catattattt
    47941 ttttcttagc gtaacttcca tctctctccc aaaactggaa gttagtctaa gacggatttc
    48001 cactgatttc acgcgttttt ctcatactaa aagctaggtt gtgggaaact ggaagttagt
    48061 tttagaagtt actatttttt cttagtacct attctagccc tgcttaaact agtaaaaaga
    48121 actcctacat ccataagtga cataggagtt taggcttatc ttttactgag ttacagttac
    48181 ttctccagtt cggtaatcca gttgaagtcc cttttgaaca ttgggaacta gaacattgaa
    48241 ttccaattct ccatccgaag acttggcttc aatctgtgaa gctgagggaa ctaaatcctc
    48301 gtttgaagcg tagtaaaggg ttacacggta acggacacgc ttgttttggt ccaaggcttt
    48361 acgcaccttg ctttcatagt agttttgacc agtcgaatac tcggcttgtg cctgatttgc
    48421 ccaggctgtc tgaacagcaa tgtttttagg attgcttgtt gaggcatcaa aaccatccaa
    48481 accaccgatt aaggcatagc ctaacaaatg acctctatcg actgcatggg tataagagcc
    48541 ctttagattc ttgacctgat gccaacctgg aggagtccaa gaagttgaac cattcccagt
    48601 ttctttacga ttcttgtact gacgagtggc cttagacaag agggcattag ctacggttgg
    48661 aacagtttcc ttgcccactg tctttgtttt attgtcagcg tagggcttac ttgaaacctt
    48721 ggcatctaga tttgttttat taccattgac gataaaagca cctgagccat tccactccag
    48781 actccccttt atttgactct tgactgcgtc tgttaagaca ctctctgcca atgcttgact
    48841 aggagcttca gacgcttgtt ttttctgact aagattggtt ttgggactat taggtgccga
    48901 ctgcatctgc ttgatataat agctccctgt agacaaaagc aataacacta gcagtccgat
    48961 tagtgtctgt cttgtttttt tgttcatatt tctccttatc tttagaaaaa ggctggttct
    49021 ccagcctaat ttcctgtaaa tttatgaatc aattcctgcc attttgctgg agacaggata
    49081 gcccatggat cttgaccctt gcccaagatt ccataaccta ccattagacc gattcctaga
    49141 gccagagtac ctaaaatcag tactatgatg actaaaagta aacgattgat tacgtagctt
    49201 gatttcttat tcatcttcat cgcttgcctc aatccgctga atcttagcac ctagctgcgc
    49261 caacttctca tggaaaccgt agtaacctct atccaagtga accaatttac cgaccacagt
    49321 ttctccctgt gctaccaaac ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga
    49381 aagaacttct gctccctgca aaggctgtcc accaacaata cgagctgtat cacggataat
    49441 ctcagaatgc aagcccatgc ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac
    49501 tgtctccacc atggttgatt cgccttttgc aactgtcatc aaggctgtaa attgagcctg
    49561 catatctgtt ggaaatcctg ggtggggcaa ggttttcaca tgaacagctt ttagattttc
    49621 tagttgagaa cgaacacgaa ttccttcgtc ttcttcaatt acttcaacac ccatttcaag
    49681 taacttggca atcaagggac ggttgtgctc ccagacagcg tctcgaatca agacatcacc
    49741 accagtcatg gcagcagcta ccataaaggt tcctgcttcg atacggtctt ggactacatt
    49801 gtgagtcgta ccatgaagtt tctcaacacc agtaatggtt atagtctctg taccagcacc
    49861 tttgaccttg gctcccattt cattaaggag aatggctaag tcaacaatct caggctcacg
    49921 cgcagcattc tcaatcactg tcaccccatc agccagagtc gctgccatca tcaagttctg
    49981 cgttgcacca acacttggaa agtccatata gatatgagcg ccatgcaagc gttctgcctt
    50041 ggcttcgatg taaccagctg tctgactaat cttaaccccc atagcttcca gacctttcaa
    50101 atgaagatca ataggacggc taccaatcgt acaaccacct ggcatggata ccttggcatg
    50161 acccacacgg gcaaggattg gccctaatac aacgatggag gcgcgcatct tgctgacata
    50221 cttgtaaggg gcttcctcag tgatgtcgcc agtagcatcc accttgacaa gatgagcttc
    50281 ctcatcaaag tcaaccttgg cattcaaacc accaactacc tgattcataa taaagacatc
    50341 cgacaaaatc ggaacattct gcaagacggt ctttccttca cttgctagaa tagtcgctgc
    50401 caacaagggt aagactgcat tttttgctcc ctcgatcgtc acgcttccta ccagacgatt
    50461 atcgccacct tgaaccacaa ttttatccat actcgtttcc tttactcttg attttataat
    50521 aatcctctaa gcgcttcttg ccacaaatga tacaggctaa taaagaaaga actcaggatg
    50581 tagcctatga caatgctaaa aaaggctact aataaacgaa cttttcttgt attatcatct
    50641 gtcactttta aaaccttctc ccatctaaca agatccttta aaaggtaaaa actcacataa
    50701 ataaagagca tatgactact tagagtgaat aataattgaa ccatttgact attataccat
    50761 cttctctgtt tgtgcgctag tttggaaact tcactcaaaa attagggatt gtttttcaag
    50821 taatcaatcg catcttgtag ggttttaacg ggcacgattt tcatatccgt cttgattgtt
    50881 ttagccgctt ctagggctgt ttggtagttg tttttcgcgt ccagatgcgc cttttgttct
    50941 tcttcgctaa cagggttatc aggagcaaag aaaatagcag cacctgccct agccgaagct
    51001 acaaccttct tatcaatacc tccaatgtct cccacattac catcgcggtc aatggtacct
    51061 gtaccggcaa caatacgacc attacgaaga tctgggtgag ctatttgagt atagatagct
    51121 agactaaaca tgagaccagc acttgggccg ccaataccag ctgttgaaaa gctaattggg
    51181 acattgctga ttacctctgt acggtcaatc aagccgattc caattccatt tttgccattt
    51241 tccaaggtga taatctttcc ttctgcagac ttggtttgcc catcctcttc ataggtgacc
    51301 ttgacggaat cccctaattt ttgagaactg acgtaatcaa tcaagtcttt ggaactatca
    51361 aaggtctgat cattgactgc tgtgactgta tcagagatat tgagaatccc tttaaaggtt
    51421 gaattatccg tcacattcaa aacataaact ccaaagtact tgagttcgat atccttacca
    51481 gctgttttta gtccttgata cttggccata ttttgcgatg tttgcatgta gaattgattg
    51541 attcgcataa attcaacatc ggaagaacca cctgtagtct cctgagcact acgaatatct
    51601 gtaaaaggtg tcaaccaagc ataaatcata tgagctaaag tggcatgttg aacaccaacc
    51661 gtaacgaatt gataggcacc agcttcctta tcttctgtgt catttacttt aaggacttgg
    51721 cgaatatctt ccgaaccacc tggaacctct atataataag gcaagggcac tacaaatgcc
    51781 aagaaagtca caatcaaggc cgcaatgacg tataagggcc atctaatctt ttttttcatt
    51841 tcttatttcc tccaaaatac tctcgggaac atggcaggca atatcctgac caaacttcaa
    51901 aagctctcga acacctgatg aactgatata gagatgttca ggccggctat gtaaataaat
    51961 agtctctata tcagaagaca gctgatgatt gtagtaatca aaactagctt catattgcaa
    52021 atccgccgca ttcctcaacc cccgtactag gaaagtagcc cccagtcttt ttgcaacatc
    52081 gaccaccaat tcatcatgag aagccacgac ttcaacattt tccaaatgtc ccaaagcctt
    52141 ttctagcccc cgtttacgat tttcaagagg gagaaatcct tgtttgtggg gattaaaaaa
    52201 aatacccaca taaagcttat caaaaagtct gctcgcccgt tcaatgatat ccagatgccc
    52261 atttgtcatc ggatcaaatg agcctgtgaa taagccaatc ttatctgaca tagactgtca
    52321 ccttactaat tccataaatc ttttccttcc agatacccag acaggcaatc tcttctggaa
    52381 gttcaacggc cttatccgtc tcgcacacaa ccataacatc ttcagaaaaa agctctctct
    52441 tagccatttt ttcaatatct gctacgattt gttccttggc atagggaggg tctaagaaaa
    52501 cgaggtcaaa ttccccagat acctgttcca atgccctctc tgcatccatc ttgaggagtt
    52561 gaaattttcc aacttccttg gtcatctgga tattttcagc cacgatggtc tgagccttac
    52621 ggtctcgctc caccaaaaca gcactggaca tgccacgcga tactgcttcg atagataaac
    52681 caccactacc tgcataaagg tccaagactc gtcccccttc aaagtaggga ccaatcatgt
    52741 taaaaatggc tcccctaacc ttatccgaag taggtcttgt tgtcttgcct tctagtgtct
    52801 tgaggggacg tcccccatag attcctgata cgattttcat actgtttatt ataccaaatt
    52861 atagacaaaa agagaaagaa aaccgaacct tgcggttcga ttctctacaa aatattttcg
    52921 taagtatcgc ggacttcttg aggccaaaca cttgtttgca cttctccgat gtgtctcttg
    52981 cgaagtagga acatggccat acgagattgt ccaattcctc caccgattgt caatgggaat
    53041 aggccattca acaaagactt gtgccattcc aattccaagc ggtcttcatc acctgtaatt
    53101 tccacctgac gtctaagagt ttcttcatct acacgaattc ccatagaaga caactcaaag
    53161 gctccaccta aagactcatt ccagacaaga atatcaccat ttagaccctt gtagccattc
    53221 tcagactcgc ttgtccagtc atcatagtct ggtgcacgtc catcgtgcgg tttaccatct
    53281 ggcaactcgc caccgatacc aatcaaaaag acggctccaa attctttaca aatcgcattt
    53341 tcacgttctt tcggtgtcaa gtctgggtag cgttctacca attcttctgt atggataaag
    53401 gtgatttgct ttggcaagat agactcgatg tcatagcgag cttcaacagc tagctcagtc
    53461 aggcgaatag ccttataaat cttctcaact gtttctttta gataaacgat gttacgctta
    53521 ccatttggga taaccttctc ccagtcccac tggtcaacat aaacagagtg ggttgcatcc
    53581 aaggaatcct catctggacg aagggctttc atgtggacaa agagaccctc tccttcacca
    53641 aagccaaaac gagccaaggt gtggcgtttc catttagcaa gtgagtgcac cacttcataa
    53701 gtagcatcag ggatttggag aaccttgacc gatactggat tttccacacc agacaggttg
    53761 tcctgcattc cgtcaccgac cttactcaag ataggacctt gaacttcgac aacttctagc
    53821 ttatctttca aatactgggt aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg
    53881 ataaaacttt tcttcataga caactcctca aaaatttaat aaacgtatta tacacctatt
    53941 tccaagaaaa gaaaagagaa aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat
    54001 agacctttta gtcattgcga ccaaagatac gtagaatact taggaaaaga ttgataaaat
    54061 caagatagat gctgagagcc attgacacca cccagcctgt cgctacacga ccttgtgatt
    54121 gttcataggc gaggcgaatc ttttggttat cccaagcaat caaccctgaa aaaaccaaaa
    54181 ccatggctac gctaatcata taatcaaaga agccactagc caagaaaata ttgactacca
    54241 tagcaatcag taaaccaatg agagctgcca tcattgctcg accaatccca ctcaagtctt
    54301 tcttggtaaa gataccaact gccgccatga caaagaagag aagggcgctc gatacaaagg
    54361 cagataaaac tgtacccgga gtatagaaag ccaccacaaa actaagggta aagccgttta
    54421 aaacggagta aagtaaaaat actggaagag cagctggact atttcttgaa gccatgctac
    54481 tggcaacgaa aaccaaagcc aactccgcaa aagtagcaat ggtcaaccag agacgcccct
    54541 gcatcaacaa gtaaaccaac tgagactgaa agaccgtcaa cataaggcct gataccaaag
    54601 cagatagtcc gattcccaga ccaacaaagg cataaacctt agcgtaaaat tgattgagac
    54661 ctgcacggtc atgtataata gtgtgattca tccttttctc cttttctgtg aacatctttc
    54721 cttgattata acaaaaaaag ttaaaattag cttaaatgga agattaaaat accggctgca
    54781 actgcaacat tcaaactctc ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca
    54841 ctttcagcca taaggggact aattccttga ccctcatttc ccataactag tacaaaattt
    54901 tctatagaag gcagttctct gtaatcaaca gaatctttag atagggttgt tgctagcact
    54961 gggatagcta cctttttagt ttcgtcaaga agcgctggac tagtcatccg gtaaatgggc
    55021 agatggaaat gactaccttg catggaacgt agggttttga gactgtagat gtctgccgac
    55081 ttatctgaaa caatcactcc tgtaaaacct gctgcatccg cagttcgaat gatagttcct
    55141 acattaccgg gatcttgcac atcttccaaa aacaagaact tgccctgact caaatcagct
    55201 tgtcctactt cttctttttg aaccaccgcc acaattccct gtggagtctg agaatccgcc
    55261 aaatctagca aaatatcctc tgacacccag acagtttgcg aaaaagtagc taactgatct
    55321 cgataatttt ctagggcaaa gattttctca atcgtcactc cagcttggac agcttcttca
    55381 aacaagtgcc agccttcaat caaataggca gacttgcggt attttttttg gcgtaatttc
    55441 ttggcatttt ttaccacaga attggctttt gaggttataa tagtcataga aatattataa
    55501 cacaatcaaa gggggttggt atgcaaaagg ttagaatgat tgcccaaggt agggtacagg
    55561 gagtcggctt tcgttggggt gtttacagct tggcacttga aattggtggc atcacaggtc
    55621 gagtatggaa taacgacgat ggcacagtgg aaatcttagc ccaagcagac tcatctgcta
    55681 tcatggcaaa atttatccaa gaaatccgaa aaggaccgac acctttttca aaagtaagct
    55741 acttagatgt caaactaagc aactttcctc cctactctga ctttaaaatc gcaaattagg
    55801 tctccagaac tattgtatat tttgtaaaaa aacagtagaa tagaaaggta taatttttaa
    55861 agaaggaata aaaacagtga aatctattaa acgttttgca ttctcggcta tgggagtggc
    55921 tatgttgctt gtcttgactg gctgtgtcaa tgtcgataaa accacaggtc agccaacagg
    55981 atttatttgg aatacgatcg gagcgcctat ggctgaagcc atcaagtact tcgctactga
    56041 taaaggtcta ggctttggtg tcgctatcat tatcgtaacc attatcgtac gcttgattat
    56101 cttaccactt ggtatctacc aatcatggaa ggcaacgctt cactctgaaa agatgaacgc
    56161 tctcaagcat gtccttgagc cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga
    56221 aaaactcgaa gcccaacaag ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt
    56281 tggtggtgta ggatgtttcc ctatcctcct tcaaatgcct ttcttctctg ctatctactt
    56341 tgctgcccaa catactgaag gggttgctca agcaagctac ctaggcattc ctctaggttc
    56401 tccaagtatg attttggttg cctgtgctgg tgtcctttac tatcttcaat cgctcctttc
    56461 acttcacgga gtagaagatg aaatgcaaag agaacaaatc aagaaaatga tttacatgag
    56521 cccactcatg atcgtcgtct tctccctctt ctcaccagct agtgtcacac tttactgggt
    56581 tgtcggtggt ttcatgatga ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa
    56641 acttcgcaaa aaagtccgtg aagaactagc caagaaccca ccaaaagcaa gtgctttctc
    56701 taaaccaagt ggacgaaaag acgttacccc tgaacaacca actgctatca caagcaagaa
    56761 aaaacacaaa aatcgcaacg ctggaaaaca acgttcgaga taagaagaaa aaggcttagc
    56821 tgatttgcta agtctttttg caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta
    56881 tccatgtaca cgtttcatat aatcttgata actttcggta tccatgagtt ttttagcgtt
    56941 cttgacgcga tctgctgttg gtggtttgac tccttcgagg gaatatggaa ttccaagttc
    57001 acgccacttg aactcaccca tggtgtgata aggtagaatt tcaaacttat caacattttt
    57061 gagggtcttg acgaacttac caagttcaat caagtcatca tctctgtctg tcaatcctgg
    57121 aactagcacg tggcgaatcc agacaggttt tccaatatct gatagatact gggcacaagc
    57181 caagatattt ttattagttt ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt
    57241 gatatccaaa agaaccaagt cagtgacagc catgagtttg tcaaacttct caaggtaacg
    57301 tggtttatta cggaaaggaa gagcacaggt atccaaggta cagtggattc cttgttcctt
    57361 agccttggtg aagagagcaa tcaggaaatc aatctgcaag agagcttctc ctccactgac
    57421 tgtaatccca cccttatttc cccagaaacc acggtagcgc aaggcctctg tcaagacatc
    57481 atctaccgtc cgttcacgtg acttattgga ctccatagcc caagtgtctg ggttgtggca
    57541 atactggcaa cgcatgtgac agccctgcaa aaagacaata aagcgaatac caggcccatc
    57601 tactgaccca aagctttctg tcgaatgcac cattcctgtc acttgtccat aatcaattgt
    57661 ttcttcagac atatcgttac cttccttgaa aacgttttat agttttatta tatcacgact
    57721 tgaaggaaaa acaagatttt tgcctatttt ttagaaagca atctgttttt caatttcatt
    57781 ttcaatctat tatcagatta ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc
    57841 tcagggcgct ctgcacggcg gatttgacgg gctttacctt cttcggtata gaggatttcc
    57901 gcagaacgta atttggcatt atactggtag cccattgaaa atccgtgggc acctgtatca
    57961 tgaattacca gcaaatcacc gatttctgta tgaggcagtt cgcgattgac tgcaaattta
    58021 tcattgtttt cacagagtga accaaccaca tctaccgctt cagctggtcc atctggatgg
    58081 gtcacgttgc taatatgatg gtaagctccg tacatagctg gacgcatgag gttgactgct
    58141 gaggcatcca cacctagata ggtacggtag gtttccttct tatgagtcac tcttgtgact
    58201 agagcaccgt gaggtgccag cataaaacga cccaattcgg tgaaaatctt gacctgacca
    58261 agacctgctg acgtaagaac ttcttcatac accttacgaa ctccctcacc aatcaaggcg
    58321 atatcgttcg gctcctggtc tggacgataa ttaacaccaa taccgccaga aagattgata
    58381 aagtctagcg aaatgcccaa cttttccttg atttcaacag ccagttcaaa gagctgacga
    58441 gccaactctg gataatagag atgggtcacg gtattggacg ctaggaagga gtgaatccca
    58501 aaagtcttgg ctcctttttc cttcaagata gcaaaggctt caaagagctg gtccttggtc
    58561 atgccaaact tagcctcccc aggattgtcc ataatgtctg tccccagttc aaaaacgcct
    58621 ccaggattat aacgacaaga gatgatttct ggaatgcctg ctactctctc cagatgttca
    58681 atatcttcaa aggcatccaa gttaatggtc gcacccaatt cacgtgcata ggcgtattcc
    58741 ttgtctggcg tgttgttgga agagaacata atctcagaac ccagaaagtc cagtttatgg
    58801 ctcatcaaaa gctctacata actagagcag tccacaccac aaccttcttc ttggagaatt
    58861 ttcaaaatag ctggagttgg agtagcctta actgcaaaat attccttaaa gcccttgttc
    58921 cacgaaaaag cttggttgac ggctcttgcc ttctcacgaa tccccttctc atcatacaag
    58981 tgaaagggag tcgggaactc ggcaacaatc gcttctaact cttctctatt gataaatggt
    59041 gttttcataa gcttccttct attctgtttg caaagaaagg ctgggacaat cgttccaacc
    59101 tttagttcta tctcttattt atcttcgtca aagatattgc caacctcaac atcgatggct
    59161 tggttcttga catcaatatt ggttaccttc aagagtgact tgtagtcaaa ctgcttttca
    59221 cgttcttctt gggcattgtc cgcaaagacc gctacacctg ccagttctga gtcgaactcg
    59281 cgcaagagac taatcatacc attgaccgtt ccgccacctt tcaagaagtc atccacaatc
    59341 aagacacggc tgcctgcctt aagactacgt tttgaaagga acattttctc gatacggtca
    59401 ccacttgaac ctgaaacata gttgacgcta acagttgaac cttcggtaat tttcaggtca
    59461 cggcgcacaa tgacaaaaga gacattgagg acattggcaa ctgcatttgc aagtggcaca
    59521 cccttagttg ctacggtcat aaccgcgtca attttttggt ccataaagct tttggcaata
    59581 atacgaccaa tatttttcaa gatggctggt gtgctaagca aatcagacag atagatataa
    59641 ccacctggca agatacggtc actttctgac aacttggtac gcaagtcttc aaccatttcc
    59701 ttagcatcct gactcgaaat agacggtgtg aagatgacac ctccgccagc cccagtcact
    59761 gtctggatat gaccgatttc aatttcctca aaggcgcgtt tgataatgac gatatcttct
    59821 gagatggatg atttagcaga ctcatacttt tcagcaaaag tattgagact agttagttta
    59881 taaggattat taatcaaata gttggaaatg acaaccatcc gatcacttct tcttaatttc
    59941 atttctattt cctattccat ttttattcaa aaaatcaaaa agcaaactag aaagctggtc
    60001 gctggtggtt caaaacactg ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata
    60061 cctgcatata tacatacgac aaggcgatac taccctagtt tgaagagatt ttcgaagagt
    60121 attcattttt gtcttttact tattatacca tattcacata aaaaaacgaa cattcttatc
    60181 ctaaaaaatg ctcatttttc ttaaattatc aatctaaatc tggtttatag aaggaacgat
    60241 tatccatagc gaagatttta ttggtcatct ctcctttatc caccaaagcc agagctgttg
    60301 acatcatcat catgcttgca tccagattgt caatcatatg gataatctct gcctccataa
    60361 tacgtggacg gactggactt ccatattcaa gcaagccgtg gtgactgagg atgacatgac
    60421 gaagcaaaac gacttcttcc ttggtatcat cgatgccgag ttccataact gtcttggtaa
    60481 tttcgctatc aatgagagcg atatgtccaa gaagattacc tcgcactgtg tactctgtct
    60541 ggtctggccc cgtcaactcg ataaccttag ctaagtcatg cagcataatc cccgcataga
    60601 gcaggctctt attgagctga ggataaactt cgctaatagc gtctgccaaa cgtaccatgg
    60661 tcgccgtatg ataagccaac cccgtttcaa aggcatggtg gttggtcttg gcagctggat
    60721 aggagtagaa ttccttatca tacttggtgt agagatttcg gacaatccgt tgccagacag
    60781 gattttcaat tttgaaaatc atttgcgaca tgtagtcacg aatttccttg acatcaactg
    60841 gtgacttgac cttgaaatcg gctgggtcat tgggttcacc agcttgaggc aggcggagag
    60901 taatttgatt gacttgaggg gtattgttat aaacttctcg gcgtcctttc atgtggacaa
    60961 ccttacctgc ggtaaaggcc tcaatgttat gaggttgggc atcccagagc ttcccatcaa
    61021 tctcgccact atcatcttgg aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc
    61081 tcaggtcagc tgatttgatt aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac
    61141 taatcttcat attcttcctc attttcttga aaatggagta gatcaagcgc aggctcacct
    61201 tctgacaact caatgtgacg gagcgtccgc tcgatagcta tggtacgacg gtttaataat
    61261 tcatcaatat tgccagaggc atgttggaga tgtttttgtg ccttgaccag aataccacca
    61321 aacttgccaa actcggtctt gacactggca agagtcttgc tgatatggtc ggcactcttt
    61381 tggatattaa gggtcttgaa accaactgat agagagttaa gaagggctga tagggtactt
    61441 ggtcctgcaa caataatctg ttcttcccgt ctcaaatcat caaagaagac cggattgcgc
    61501 acaatctctg aataaagacc ttctgtcgga acaaacaaga ttccaaagtt ggttgtccga
    61561 ggtggtgcta tgtacttgtt cctaatatcc ctagcaaagc gcttgacgct tgctaggagt
    61621 gacttacgac agcgttcaat ctcatccttg tcacctgtct cataggcttc ttccaagcgg
    61681 taataatctg ccagtggaaa cttagagtca attggcagat agacgtattc ttggtcgcct
    61741 tgtccgggta acttgatggc atactccact cgttcactag agttttcaac cgttgcgtat
    61801 tctcgttcgt actgggcagg tgtcatgatg tcttcaataa tttgccccag ttgcaattct
    61861 cccagaatcc ctcgcgtctt ggttccagag agaaccttgt taagagctcc gacatcacgg
    61921 gcaactgtct gcatttctcc aaggccacga ttgacagact ccagttgttt agaaactgtc
    61981 tcaaaggaag cctgtaagcg tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg
    62041 cgcatttgtt ccaaacgttg ctcatttgat tcctgcaagg cttggagacg ttggtctgtc
    62101 ttgtctctag tttggaggag attatctgtc atttcttgac ggacttgggt cagaccttgg
    62161 tgcaattcaa tccgcacttc ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg
    62221 tctaactggc tggcttgtct ggcttggtca aagcggtaat ccaactggtc tgacaaatga
    62281 tctgcctgat cctccaagct cttacttaag tgtttctcct gcctatcctg cctttgccaa
    62341 atcagaaaga gaccagctag attggcaatt aataatagaa taagtaaact ttccatccta
    62401 cctcctgtcc ttgctatgca gtacgaccac ataaccatct gggcaagtta ccgacacttc
    62461 cctatctata tattcgttag aagcgtacac ttttttaaag aaaaaatttt cctctgtcaa
    62521 ctcatacttg gctccaagaa tagtcagctg gctatcccga actggcataa aggctagata
    62581 gtcgtagtct gaacgaggtt ctagctgact gattccttct ggacaataag taatcaagtt
    62641 ttgcccatcc tcaatttcta tttgatgcat atagggtgcc aacttaggat tgctaggcag
    62701 aaagacattg gccaacatat ggtcaatacg gccacccaag gcaccgaaaa tagtaacctg
    62761 agcctgagga ttttgcttaa agatggtcaa gagagccaat tccaaatcag tatcatcttt
    62821 ttctggccgg gcttggacaa aatactgggc acgtttttga atcacctgtc gctcttcttc
    62881 cgtcacagaa tcaaaatctc cgactgctag agcaagaggc aaatcttctt ccaagatcca
    62941 gagcgagcct cgatccacac caacaaaacc atcaaagtcc gtccgataat gaccgcggtc
    63001 tccgcctgca aaaacggcaa ccctagtcca gttgttttct gagagtttgt actcgctcat
    63061 tgacatctcc cttaaagaca taggaacctg ctacaaaaac ggtcgcacca gcttctttgg
    63121 attgagcaat agtttggtca tcaatcccac catccacttc aatctcaaag ttcaaacctt
    63181 tttcatcacg aagggcaacc agctcacgaa ccttatccat ggtttctggc agaaaggctt
    63241 gaccaccaaa tccagggtta actgtcatga ctaggacttg gtcaactaga tgaagcacat
    63301 gcttaatcgc ttcaactggt gtaccaggat tgataacaac tgatggcttg acaccgagtg
    63361 aacgaatctt ttggagggca ccatgaatat gaggcgttgc ttccacatgg atactaataa
    63421 tatccgcacc tgcacgcaca aagtcctcta aatgatgctc agggtttgac accatcaagt
    63481 ggcagtcgaa aaccatctta ctatgaggac gaagagcttc gaccacaccc gcaccaaaac
    63541 tgatttgcgg cacaaaatga ccatccataa tatcgatatg ggcatactct gccccagttg
    63601 cttctaggcg tttaatttca cgttcaaagt tggcataatc tgctgccaga attgacggag
    63661 caatcttgta ttgagacata ggtttctcct tattttggaa tttttttgct gactttttta
    63721 taggtttctc tgcgattttc aatttcgctg aggaattgca ggtagttgtc aaaacggaag
    63781 ggtgcaatgg taccttcttc aactgctggc ttgacagcac aggacggctc atgggtatgg
    63841 gtacaagtac ggaatttgca gtctcgactg acagtggcaa tctctggaaa ggcctgattg
    63901 aggtcttcag ccgttgatac ttcataatcc agtgatgaaa agcctggtgt gtctgcgatt
    63961 ttacccccat tgaggttgta aaaactaaca gctcgagtgg tatgacgccc gcgacccaga
    64021 ctgtctgaaa tttctcccgt ttcaagatta agatctggtg cgattttatt gagaagagtt
    64081 gatttcccaa cacccgtctg ccccataaag accgtaacct tgcctgttaa caaaggcagg
    64141 agttcctctt tactggtcac aaagtcatat ccgatgtcac cataggtctg ctggtaaaaa
    64201 tccagttctc ccccgtcttc caacaaatcc attttagaaa tatagacgat gggatgaata
    64261 cccttatgct ccaaaagaac caagaaacga tccagcaaat tgctgttaaa atcaggttcc
    64321 ttgacagaca tgattactac agcttggtcg atattgacaa taggcggacg gaccagactg
    64381 tttttccgtt cgtgaatctt gagaatatag ccttctgaat tttcctcggc agagaaatct
    64441 acccagtccc caacgtaagg ggtatgccct tttttacgga aattcccacg cgcgcgtgtt
    64501 tgatagactt ggccatcact ctctacatag tagaacccag ccaaggcttt aatgatttgt
    64561 ccctgcaaaa taactccttt aaaattgtta gttccattat aacaaaaaaa agctatttta
    64621 gcttagcttc tctttacaat ttcgataagt ctattctaaa agaaaaagat acactcacgc
    64681 tttagatacc aagttttata caaaaataac gaatctacct ccttatataa aaacaggcga
    64741 acagagagcc taaaactccc tgttcgcttt actttttctg tgtgtaatag aaaaaaccta
    64801 ataaagcaag acaaaaaata tgaatataaa ctccatacat catgtgggga aagacagact
    64861 ctataaaata gcctggtaga tagatgattg gaaattgata gaaatcatag gtcgttagag
    64921 atagtaaaca aagaacatac ataaatactg ctacaattag aacccatcct tgctttcgcc
    64981 atagaaaaat catcaataag aacagacaaa gtagatagat tgaccaattt cgcaacataa
    65041 attgaaaacc ataaatcata ctttcagtcg tttctccatc aatcacatca actactttat
    65101 agaaaggtaa acaatagctc actaaaaaaa gaaggggact aattattttt ttcatattct
    65161 ctaccatgga ttattttgca agtaagctga ccatctatct ccatatcgaa tcaaattaac
    65221 agtataatta gttactaccc gattttcacc tggtccaacc ttagaaaaac ctgtgctata
    65281 ctcccaacta cttcttgcac ctggatgaaa ccatttttgc tgggatgaat accaaccacc
    65341 ttgtctaact tccacacttg aagattctat ttcgatatcc ctttcatgga agtcaactcc
    65401 tccacttatt ttagtaatat ttttttgtac acctccatca taactcaccc agtgaacaac
    65461 agtatacaat tccacactat aagtactatc aaactgactt tgatgagtag taatgttttg
    65521 agtataagcg tgcactttct gtataccaaa aatatggtct aatatattcg ttggtttagc
    65581 aagcttattg taaccctctt caacaaaagt agccttctct aaatcagcgg tataaacagt
    65641 ttttccttgt actacttgat tgtttataga agtaatacgg ctatccacaa caatgggggc
    65701 caccatatct ccatcgctag tttctatttt agctgcctct ttcacctcat atacaactcg
    65761 attttcttca gactgaatca cttctacccc atttttttca ggtatagata atctagtttg
    65821 cccattagaa accgttatat ttggaccaat attcttctca tttgcataag tcgcaatagg
    65881 aaatcctgat agaaccactg cacacataag gctattgact aatttttttc tcatgaatat
    65941 atccttccca ttttcaagag gagtaaaaat agctaatata agatgaacgt ttccttatat
    66001 ttcagaatag gatatctatc tgaaagcaat tcacactcct ataggtaact gttccaaatc
    66061 ttggctacat atatttcaat agtttgctac aaaaaactcc tttctaagtc tattgaacat
    66121 gcccttattc acctactaat atatcacaaa aataaataaa tacaagactg ttttttctac
    66181 tagttttatg atagaatagt attgttaggg taaatttcat atataaatgt cgagtgaaaa
    66241 atcgatggag cagaaatcgg tagacaaaga ctcgatttcg ttggtccagc cccacaaggc
    66301 taatcaggta tttcacgagt ttaaaaatct aatgaagtgc ccaatcaact actgattcat
    66361 tgatttaata cgaactatag tggattgaac ctagaaatag tacactaagg attctaaaac
    66421 gtttctagaa attaatttga ctttcctaat ctctttgttc atatcttatt tcaatctact
    66481 atatatacca aaatgctggg acaaaagtct ttaaaatcag agaaacgcat attatcaggt
    66541 gttggaaaac cttgataata tgcgttttat catagaaaga tctacttcat tttttaccaa
    66601 aattaagttt ttgtccctgc atcttagagt ccttgccctt taagtgcatc tgctaggctg
    66661 gcaaactctt ccaagctgag agcttcccca cgcacacttg gtgacaagcc tgcttggtcc
    66721 aaagccttgg tcagcttgtc cttgacctct tcagtcttgc caaagtaacc tgtcaagtta
    66781 ttccacaagg tcttgcggcg atgggtaaaa ctagccttgg aaaccttaaa gaaaaagttc
    66841 tcgtcttcca ctgctacagc tggcactgga cggcgcacca ttttcaagat ggctgagtct
    66901 acatttggtg ctggcacaaa gactgtacgc ggcacgataa aggcaacctt ggctgtcatg
    66961 taatactgca cagcgataga caagctaccg taagccttgg tatttggttg agccgagata
    67021 cggtccgcca cttctttttg catcatgacc acaaactcac taaaaggaat gccactctcg
    67081 attaagtgca tgagaatagg cgttgtgatg tagtaaggca aattagccac taccttgatt
    67141 ggcaggtcag gatttttgaa attctggata tgttgcgcca aatcgacctt gagaatgtcc
    67201 tcgttgacta cagtcacatt gtcaaaatca cgcaaggtat ctgccaaaat cggtaccaaa
    67261 cgatggtcga tctcaaaggc cataacttct gctgcacgct cagccaaaaa ctcggtcaag
    67321 gcaccaatac ctggcccgat ttcaatgaca ttgacctggt catcaatctc agccgtatcc
    67381 acgatttttt gtaggatatt ggtatccgtc aagaaatttt gcccaaagga ctttttaaag
    67441 gtaaaaccgt gacgctccag cactgccttg gtcacgctat aatctgcaat tctcatctat
    67501 tctcttttct attatctgtt actactattg taacacattc cccttgtatt ttgggggtga
    67561 aaatcatacc aaaaaactat ctttcctcat gaagaaagat agtcttggaa atctttaaaa
    67621 gtggccttag cgcttctctc gaaacatacg tt
//
LOCUS       DAVBOH010000006        64468 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOH010000006 DAVBOH010000000
VERSION     DAVBOH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.006"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(15..1973)
                     /gene="ftsH"
                     /locus_tag="VQ873_000358"
     CDS             complement(15..1973)
                     /gene="ftsH"
                     /locus_tag="VQ873_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3106691.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1989..2531)
                     /gene="hpt"
                     /locus_tag="VQ873_000359"
     CDS             complement(1989..2531)
                     /gene="hpt"
                     /locus_tag="VQ873_000359"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3106692.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2535..3812)
                     /gene="tilS"
                     /locus_tag="VQ873_000360"
     CDS             complement(2535..3812)
                     /gene="tilS"
                     /locus_tag="VQ873_000360"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3106693.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3809..5077)
                     /locus_tag="VQ873_000361"
     CDS             complement(3809..5077)
                     /locus_tag="VQ873_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3106694.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5197..5565)
                     /locus_tag="VQ873_000362"
     CDS             complement(5197..5565)
                     /locus_tag="VQ873_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3106695.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5558..5824)
                     /locus_tag="VQ873_000363"
     CDS             complement(5558..5824)
                     /locus_tag="VQ873_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3106696.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5882..9391)
                     /gene="mfd"
                     /locus_tag="VQ873_000364"
     CDS             complement(5882..9391)
                     /gene="mfd"
                     /locus_tag="VQ873_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3106697.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9392..9961)
                     /locus_tag="VQ873_000365"
     CDS             complement(9392..9961)
                     /locus_tag="VQ873_000365"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3106698.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10032..11147)
                     /gene="ychF"
                     /locus_tag="VQ873_000366"
     CDS             complement(10032..11147)
                     /gene="ychF"
                     /locus_tag="VQ873_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3106699.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11231..11425)
                     /locus_tag="VQ873_000367"
     CDS             complement(11231..11425)
                     /locus_tag="VQ873_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3106700.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11490..12626)
                     /gene="dnaN"
                     /locus_tag="VQ873_000368"
     CDS             complement(11490..12626)
                     /gene="dnaN"
                     /locus_tag="VQ873_000368"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3106701.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12785..14146)
                     /gene="dnaA"
                     /locus_tag="VQ873_000369"
     CDS             complement(12785..14146)
                     /gene="dnaA"
                     /locus_tag="VQ873_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3106702.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAEVIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14359..15117)
                     /locus_tag="VQ873_000370"
     CDS             complement(14359..15117)
                     /locus_tag="VQ873_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3106703.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15175..16356)
                     /locus_tag="VQ873_000371"
     CDS             complement(15175..16356)
                     /locus_tag="VQ873_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3106704.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16539..17018
                     /gene="rlmH"
                     /locus_tag="VQ873_000372"
     CDS             16539..17018
                     /gene="rlmH"
                     /locus_tag="VQ873_000372"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3106705.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRITLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17062..17135
                     /locus_tag="VQ873_000373"
     tRNA            17062..17135
                     /locus_tag="VQ873_000373"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17096..17098,aa:Arg,seq:tct)
     gene            17300..17425
                     /gene="comC"
                     /locus_tag="VQ873_000374"
     CDS             17300..17425
                     /gene="comC"
                     /locus_tag="VQ873_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3106706.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17446..18771
                     /locus_tag="VQ873_000375"
     CDS             17446..18771
                     /locus_tag="VQ873_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3106707.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18768..19520
                     /locus_tag="VQ873_000376"
     CDS             18768..19520
                     /locus_tag="VQ873_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106708.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19572..19643
                     /locus_tag="VQ873_000377"
     tRNA            19572..19643
                     /locus_tag="VQ873_000377"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19605..19607,aa:Glu,seq:ttc)
     gene            19649..19722
                     /locus_tag="VQ873_000378"
     tRNA            19649..19722
                     /locus_tag="VQ873_000378"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19683..19685,aa:Asn,seq:gtt)
     gene            complement(19763..20305)
                     /locus_tag="VQ873_000379"
     CDS             complement(19763..20305)
                     /locus_tag="VQ873_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3106709.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20484..21251
                     /locus_tag="VQ873_000380"
     CDS             20484..21251
                     /locus_tag="VQ873_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3106710.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21255..21674
                     /locus_tag="VQ873_000381"
                     /pseudo
     CDS             21255..21674
                     /locus_tag="VQ873_000381"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21702..22016
                     /locus_tag="VQ873_000382"
     CDS             21702..22016
                     /locus_tag="VQ873_000382"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3106711.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22117..24669)
                     /locus_tag="VQ873_000383"
     CDS             complement(22117..24669)
                     /locus_tag="VQ873_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3106712.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24731..26353)
                     /locus_tag="VQ873_000384"
     CDS             complement(24731..26353)
                     /locus_tag="VQ873_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3106713.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26559..27584
                     /gene="trpS"
                     /locus_tag="VQ873_000385"
     CDS             26559..27584
                     /gene="trpS"
                     /locus_tag="VQ873_000385"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3106714.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27736..29214
                     /gene="guaB"
                     /locus_tag="VQ873_000386"
     CDS             27736..29214
                     /gene="guaB"
                     /locus_tag="VQ873_000386"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3106715.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29265..30362)
                     /gene="recF"
                     /locus_tag="VQ873_000387"
     CDS             complement(29265..30362)
                     /gene="recF"
                     /locus_tag="VQ873_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3106716.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30365..30733)
                     /gene="yaaA"
                     /locus_tag="VQ873_000388"
     CDS             complement(30365..30733)
                     /gene="yaaA"
                     /locus_tag="VQ873_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3106717.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30892..32142
                     /locus_tag="VQ873_000389"
     CDS             30892..32142
                     /locus_tag="VQ873_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3106718.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32139..33422
                     /locus_tag="VQ873_000390"
     CDS             32139..33422
                     /locus_tag="VQ873_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3106719.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33464..34285
                     /locus_tag="VQ873_000391"
     CDS             33464..34285
                     /locus_tag="VQ873_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3106720.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34296..34841
                     /gene="pgsA"
                     /locus_tag="VQ873_000392"
     CDS             34296..34841
                     /gene="pgsA"
                     /locus_tag="VQ873_000392"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3106721.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34838..35665
                     /locus_tag="VQ873_000393"
     CDS             34838..35665
                     /locus_tag="VQ873_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3106722.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35650..36489
                     /locus_tag="VQ873_000394"
     CDS             35650..36489
                     /locus_tag="VQ873_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3106723.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36482..37276
                     /locus_tag="VQ873_000395"
     CDS             36482..37276
                     /locus_tag="VQ873_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3106724.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37335..38153
                     /gene="mreC"
                     /locus_tag="VQ873_000396"
     CDS             37335..38153
                     /gene="mreC"
                     /locus_tag="VQ873_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3106725.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38153..38647
                     /gene="mreD"
                     /locus_tag="VQ873_000397"
     CDS             38153..38647
                     /gene="mreD"
                     /locus_tag="VQ873_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3106726.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38741..39919
                     /locus_tag="VQ873_000398"
     CDS             38741..39919
                     /locus_tag="VQ873_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3106727.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40143..40922
                     /gene="rpsB"
                     /locus_tag="VQ873_000399"
     CDS             40143..40922
                     /gene="rpsB"
                     /locus_tag="VQ873_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3106728.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41001..42041
                     /locus_tag="VQ873_000400"
     CDS             41001..42041
                     /locus_tag="VQ873_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3106729.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42287..42574
                     /gene="tnpB"
                     /locus_tag="VQ873_000401"
     CDS             42287..42574
                     /gene="tnpB"
                     /locus_tag="VQ873_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3106730.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42765..43033)
                     /locus_tag="VQ873_000402"
                     /pseudo
     CDS             complement(42765..43033)
                     /locus_tag="VQ873_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43030..43428
                     /locus_tag="VQ873_000403"
     CDS             43030..43428
                     /locus_tag="VQ873_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3106731.1"
                     /translation="MDAPIPKAPLAHSFGSASIIAHIIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43625..44545)
                     /gene="cysK"
                     /locus_tag="VQ873_000404"
     CDS             complement(43625..44545)
                     /gene="cysK"
                     /locus_tag="VQ873_000404"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3106732.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44830..45465)
                     /locus_tag="VQ873_000405"
     CDS             complement(44830..45465)
                     /locus_tag="VQ873_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3106733.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45521..46819
                     /locus_tag="VQ873_000406"
     CDS             45521..46819
                     /locus_tag="VQ873_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3106734.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46816..47478
                     /locus_tag="VQ873_000407"
     CDS             46816..47478
                     /locus_tag="VQ873_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3106735.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47558..48106
                     /gene="raiA"
                     /locus_tag="VQ873_000408"
     CDS             47558..48106
                     /gene="raiA"
                     /locus_tag="VQ873_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3106736.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48242..50215
                     /locus_tag="VQ873_000409"
     CDS             48242..50215
                     /locus_tag="VQ873_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3106737.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50212..50664
                     /gene="rplI"
                     /locus_tag="VQ873_000410"
     CDS             50212..50664
                     /gene="rplI"
                     /locus_tag="VQ873_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3106738.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50708..52060
                     /gene="dnaB"
                     /locus_tag="VQ873_000411"
     CDS             50708..52060
                     /gene="dnaB"
                     /locus_tag="VQ873_000411"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3106739.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52062..52328
                     /locus_tag="VQ873_000412"
     CDS             52062..52328
                     /locus_tag="VQ873_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106740.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52417..53763
                     /gene="cbpD"
                     /locus_tag="VQ873_000413"
     CDS             52417..53763
                     /gene="cbpD"
                     /locus_tag="VQ873_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3106741.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     regulatory      53846..53948
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54019..54309
                     /locus_tag="VQ873_000414"
     CDS             54019..54309
                     /locus_tag="VQ873_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3106742.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54272..55030
                     /locus_tag="VQ873_000415"
     CDS             54272..55030
                     /locus_tag="VQ873_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3106743.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55068..56075
                     /locus_tag="VQ873_000416"
     CDS             55068..56075
                     /locus_tag="VQ873_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3106744.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56075..56803
                     /locus_tag="VQ873_000417"
     CDS             56075..56803
                     /locus_tag="VQ873_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106745.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56922..57380
                     /locus_tag="VQ873_000418"
     CDS             56922..57380
                     /locus_tag="VQ873_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3106746.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57382..59814
                     /locus_tag="VQ873_000419"
     CDS             57382..59814
                     /locus_tag="VQ873_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3106747.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60456..61109
                     /gene="rr06"
                     /locus_tag="VQ873_000420"
     CDS             60456..61109
                     /gene="rr06"
                     /locus_tag="VQ873_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3106748.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61106..62437
                     /gene="hk06"
                     /locus_tag="VQ873_000421"
     CDS             61106..62437
                     /gene="hk06"
                     /locus_tag="VQ873_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3106749.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62520..63047
                     /locus_tag="VQ873_000422"
     CDS             62520..63047
                     /locus_tag="VQ873_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3106750.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63126..>64468
                     /locus_tag="VQ873_000423"
     CDS             63126..>64468
                     /locus_tag="VQ873_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3106751.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT        20217 a        10991 c        12762 g        20498 t
ORIGIN      
        1 agcctctctc agggttattt ttcgtcattc atttttgact ttacttcatc ataggatagt
       61 gcatgagatt cctcttctac tgcttcaggc atctttcctg tttcgtaaag agctttaatt
      121 tgtgtactat ccaatgtttc gtatttcaat aatgcttctg caattaactt gtgaatttca
      181 cgatttgact gaataatttc agcagcttta tttcgtgcct catttaataa tgaacgaacc
      241 tcttcatcaa tttcataagc tgtttgttct gaaattgatt tttgaggact ctgtgcacca
      301 aacatagcat ggtttccttc atattgtact gggccaagtt tttcactcat accgtactct
      361 gtaaccattg cacgcgccat ttgtgtcgct tgttcaaagt cgtttgaagc tcctgtagtt
      421 tggacattaa agataatttc ttcagctaca cgtccaccca ttaagccagc caattgctct
      481 ttcatatctt ctttagatag aagcatttga tcctctttag gaagtgcaat catgtatccg
      541 cctgcacggc cgcgtggtac aattgtaacc ttatggacaa cgcgagcatt cgacaagact
      601 agaccaacaa tggtatgtcc tgcctcatgg taagcaacca attctcgttc tttttgtgaa
      661 actgtcttat ctttcttaga aggtccagca ataactctat cttctgcttc atcaatatct
      721 gaagcatcaa ttatcgattt attgcgacga gcagcaacta aagctgcttc attcaagaca
      781 ttctctaaat cagcaccaac aaagcctgga gtttgttgag ccactaattt caaatcaaca
      841 tcttctgcta aaggcttgtt cttagcgtga actttcaaga ttgcttcacg acctttaaca
      901 tcaggacgac caaccaatac ttttctatca aaacgtcctg gacgcaaaag ggcaggatca
      961 agtacatctg aacggtttgt cgcagcgatg acgataatcc cttcatttcc ctcaaaacca
     1021 tccatctcaa tcaaaagttg gttcaaggtt tgttcacgtt cgtcattacc tccgccgaga
     1081 ccgactccac gttgacgtcc aacagcatca atttcatcga taaagatgat agctggtgct
     1141 gcttttttgg catcctcaaa aagagagcga acacgactag ctccaactcc gacaaacatt
     1201 tctacaaagt cagaacctga gatactaaag aatggaacac ctgcttctcc agcgactgcc
     1261 ttagcaagca aagttttacc tgtccccgga ggtccctcca aaagaacacc tgctggaata
     1321 cgggctccaa gttttgtgaa tcgttttgga tcttttaaga actcaacaac ttcaactagt
     1381 tcttgttttt cttcctcagc tccagcaaca tctgaaaatc ttactttaat atcttcttta
     1441 tttgctgctt tagccttact acgtccaaaa ctcattggat tacggccatt gcctcctccc
     1501 atatttccca tcatagagaa taggaagaag aatagaattc caaatggcac aatggatacg
     1561 agtagattaa tccatatacc acttgaactt tcatgcttaa cagttacttc tgctttatgg
     1621 tcagtagcaa gtttttgcaa ttctgatacg gtagtatctg caggaagaat agtgctggta
     1681 aatttctcta ccttagtaac agatggcgtg aaaaactgaa tacctgtttc ttctttactt
     1741 gttttaggat ttttatagac accagaaact tcgataacac taccatttgg ttggtaagtt
     1801 aattctttta cattaccatc ggtaatttct tgtaccaact cagtatagtt gatttgctga
     1861 cttcctcctg agttattccc agaatagaaa tactggaatc ctgtcacaag gaaaaagata
     1921 aataataacc atagaaaagg atttttaatt aaaccattat tttgtttttt cattaaagat
     1981 tattctttct aatttgaata cacttcctct ttcaatactc caatataagg aagattacga
     2041 taattttctt tgtagtctaa accataacct actacaaact catttgggat agtaaagcag
     2101 gtatagtctg cctcaatttc tacaacacgt ccttctggtt tatccaacaa ggttgcaatt
     2161 ttaacagaag ctgcttctct tgctttaaac atatctcgca aattcttcaa agtttgacct
     2221 gtatcaatga tatcttctac aaatagaaca tgtcttcctt tgatatcttg agtcacatct
     2281 tgtttaatat tgataacacc actacttgct gttccaccat ggtagctaga aaccatcatg
     2341 aagtccattt caatatgtgt atcaatatgt ttgaccaatt cagccataaa aggaatagat
     2401 ccttttaaaa tcccaactaa gattggattt tttcctgcat agtctttagt taattgagca
     2461 cctagttttt tagctgcttc tgtaatttca tcgtgtgaaa cgaggacttt tttaatatcg
     2521 ttttctaaca ttttttacct atctattttt tctatataaa gtacagtgtt cattatatca
     2581 tttttcgttt ttttactcaa attattggtc gcaattccca aaattgagac aatttcacca
     2641 aattgctcaa taataagagc agagtttctc ttttccatag ggattttcaa atcaataaat
     2701 aaacgtctga gtttttttct atgcccattt tgaatcaaaa catctcctgt ttttcgatga
     2761 cgaatgtgta tggatgtttc acgtgaaaca ggtatttgtt gaattgattc accttctaat
     2821 ggaagtccaa aggaaaataa atatccttga taagctacct gattttgata gtgtaacaca
     2881 agttcatctt cctcttcatc agcctgcgga ctgattttac aaatctgaaa ctgttggtac
     2941 tcttttatca attcatagcc atttttaatc ggatgacgat actggctttt agattttaaa
     3001 atctgctgaa cttcagcaaa ctgagctttt gtaagattca aatctggaaa acgattcaga
     3061 taagtttgaa gtaaaactct ttgtgtagac tcagagtaag aaaataactg ctgtaaatct
     3121 tccacattaa tattgttaga taattcagct attgccaaat cataatctaa aatttcattg
     3181 ccaatgccta agattgcatc cctaaatcga ggattttctt tttccaattc tggtaagtaa
     3241 gagtttcgaa tacgatttcg aaaataatga ttctcctgat ttgatgtatc ttcaaagtga
     3301 aaaattgatg gaaagtcttt tttctgaaaa tgcaagaagg gacgaatgat ttctatctct
     3361 ccgactactt gcttctcctt aattcctgat agatagcgca agcgagttcc tcgaatcaag
     3421 cgcatcaaaa tcgtttccac ctgatcatca gcatggtggg cagtgactaa agctgtcgca
     3481 cctgtctttt tcatgacctc ttgaaaaaaa tcataacgaa aatttcgtgc acgcgcttct
     3541 gaaaattctc ctgaaaaatt gctgatataa ataggaagct ctgcttcagc agccaacttc
     3601 cttaattcct tttcttccca atctgattca attctctgct tatgattcac atgagctaga
     3661 atcaattcaa tctctaactc tttttgataa gtagacaata ccttaaatag aaacatggaa
     3721 tctaatccac cagaaagagc tagaaccgcc ttagcatgct ttttgaaata tcccttcttg
     3781 agaaaatgat ttaaaaaatc tggttccctc attttagaac ctcataaaca tccttggcta
     3841 tcttagaaat cgtatcataa tcagaattct tagtgaaaat agaaagaata aatggagaat
     3901 ctgcatagac aacacccgta tcatgcttaa attcatccgc atctccaatt ttatgagcta
     3961 ctttaacaga aacacctttg gcaattcgct gactatcaaa atctgtttta gtcaaagact
     4021 ctaacacaaa tccattttga ttataaatag cttccataaa cttcccggcc atcttagaag
     4081 aaatcaattt ttcttttgga tcccaatcat ctcccataat ggcagacatc ttggatttga
     4141 atgtggcatc agattggttt gaaatgtaat atcccaatag attatgagct acattatcag
     4201 attcttttga tactttcgta attaaatcct ttaaagaata ttctttatta tcttcttttt
     4261 taggaagact accacttccc tctggtttat aagaacctgg aaaatcattg actgcagata
     4321 cgtattttac agtcgtatct aactgataaa gaccctcatt tattttttct tgcgtataat
     4381 agagataaga gagtttcaaa acgctggctg catacatctt ttcatcttga ttgataccag
     4441 cttcttttcc agtagtcagt tgcttaacat aaatagagaa agaatctttc tgatattttt
     4501 cagataacat ttcttgaact ttactcatcc gattatcttc ttcagaagtt gattctttag
     4561 ctacccatcc agcctgatca atatgtagaa attctcttcc ttctacaaac atggtcttgt
     4621 cgattgatac ttgcgaataa gctgataagg atgatttcac ttcttttaaa tcataaggac
     4681 tattgtacag tttaaagtca gattctaacc atgctttttt tattgttgga gttacctctg
     4741 attgatcata taaaaatcgt ttgtccgcag ctataaattg atgatttgat agcttaaata
     4801 ctggaattcc ttgtttattt aagcgccact cggttatttg aaaacttgtt ttgggagtca
     4861 atttcccaga ttccactact aaatcttcat tcgcataaac aggaacctct ccataaacca
     4921 tgggagaact taatttttct ctaaaataaa taccaaagtc agattgtgaa aggtaataaa
     4981 tttctttcga agtatagacg acttcttttt ctgtactaac gacttttgaa atggtcaaaa
     5041 aacttggtag caacaaaata attaagaatt tacgcattct tcctttcctt ttcttcttgt
     5101 aaacgcaata attgattttt atcagccaat tcttccagct tttcatctga caaactcaaa
     5161 aattgctcta ttacgtctaa taaattttcc attttatcac ctttgaagca agtcaggaat
     5221 cgtataaact ttttccctcg acttagaata atagtacttc gctcgtgtat atttggcagc
     5281 ataatcttca tctttcaact tggtagcaaa tgctgtctcc ttatcctttt catcactcaa
     5341 agtttgatac tgagtttgca agtctgctaa ttgctgacgt ctttggagta attgctgata
     5401 actctgcgct aaattaaaag ttggcaagat aaataatagc ataatcaaaa tcaatacccc
     5461 tcccataaaa cgattccgtt tttgtcgttc tttcatcagg tagcgacgac gttggtattc
     5521 attttgaata aaagaattat tcaattgtac aatattttta gacattttct tctacccgtg
     5581 tttcactgat aatttcatac attcctgctg catcttcttt ttttgtacta tctttcatct
     5641 ctagtacttt tacaagcagc aacttattgc caaagcgaat ttcaacttgg tcattaactt
     5701 tcaagtccgt tgaacttttg gccaagattc cattaacctt gattctacct ttatctgcta
     5761 cttcctttgc gactgtacga cgcttgataa ttcgcgatac ttttaaatat ttatctaatc
     5821 tcatccttat tacctcaatt tattattgta ccatttttat ctattttata gaagaaaaat
     5881 atcaaatgga attttcttcc ttagactctt ttatctctaa taaactttct ccaaaaatca
     5941 gcagaccttc taaaatttca taatctttct tattttggac atcaaataca agctccatta
     6001 atcccttatt ctcagcgatg cctgctttta agttcgttac ggataaagct ttaaaataat
     6061 cttgagctaa aaacaatcgt tgagtgactt tttcaaattg aattgtaatt ttattatctt
     6121 ttctttccac acgttgaaca aagaccttgt ccaagtatga tttaaccaaa ccaatctcta
     6181 aaagataggc tactacatct gggtattctc caaaacggtc tatcaactcc tcttgtaact
     6241 cttcataatt gacacggttg tcaatttgac gaattttctt gtaaatttca atcttatgtc
     6301 gttgatcaga aatataagta tcaggaagat aggcatcaat ttgcaaaatc aactcagcat
     6361 tccctttggt tcttgtgtta gcgttagcat taccgtttcg tttagcaata gcttcctcta
     6421 ataactgcga atacaattca aaaccaacag aatcaatgaa accagactgg gattttccta
     6481 aaagatttcc tgctccacga atcgaaagat ctcgcattgc aatcttaaag ccagagccca
     6541 attctgtaaa tcctttaatc gcttctaatc tcttttcaga gacttcactg attgattttt
     6601 ctggacgata catgagataa gcataagcaa tacgattact acgaccgact cttcctctta
     6661 actgatataa ggttgacaag cccatatggt ccgcattttc aataaataaa gtattagcat
     6721 ttggaatgtc cacccctgtc tcaataatag tagtcgtcac caagatatcg tattgtccct
     6781 caataaagtc taatagagta ttttccaact ggacttcact cattcgacca tgaacatatc
     6841 caatcgaagc ctctggaatc aactcctgta attctgaaac cttctgaaca attgtatcaa
     6901 ctttgttgta aagataataa acttgacctc cacgctccat ttcacgcaag acagcatcac
     6961 gaatgacact atcattcttt tccaaaacat aggtctgaac aggatagcga ttagtcggcg
     7021 gagtttcaat aacagacaaa tctctgattc ccagcataga catatggagg gtacgaggga
     7081 ttggcgtagc ggtcaaggtt aggacatcca cttgtttctt cagttctttc aaagtttcct
     7141 tatgcttgac accaaatcgc tgttcctcat caataatcat caagcccaaa tcagcaaaca
     7201 caacatcttt tgacaaaaca cgatgtgttc caatcaaaat atcgacttga ccgtttttca
     7261 atttttcaag tgttgcagtc tgctcttttt tacttctaaa gcgactcaac acatcaacat
     7321 taactgcaaa attttggaat cgttccttaa aattcgtata gtgctgttgc gctaaaaccg
     7381 tcgtcggaac tagaatgaca acctgtttgt gatcattgac tgctttaaag gctgcacgca
     7441 tagcaacttc agtctttcca aaaccaacat ccccaactaa aagtctatcc attggctgag
     7501 aagcctgcat atccctcttg atttcctcaa tactacgaag ttggtcatcc gtttcaacat
     7561 aagggaaagc atcatcaaag gcatcttgat catcatcatc agctgagaaa gcaaaaccct
     7621 tcaactgact acgttcagag tagagtttga ttaaatcatc agctatatcc tctacctggt
     7681 tcttaacctt ttgcttggcc tttttaaaat gaccgtcatt taatttattg agttttggag
     7741 ctttaccatc acttgaaata tatttggaca gtagatgaat ctgttccacg ggaatagaaa
     7801 tttgatcacc attttggtat tggacactga cataatcacg atgaattccc ttgatttcaa
     7861 tggtttcaat tcctagatat tgaccaatcc catggatatg atggacaaca tagtcccctt
     7921 tttcaagttc attgtaatct tttaatctct ctgcatttga aacatgttgt cttcgaaaac
     7981 gacgctttaa tttcttttga aaaatctcat gttcagttat caataaaatc ttttcatcta
     8041 caaaatgaaa accatgtctg agattacctt ctattaagtt tacagattct ttacagatac
     8101 ttgtcttatc tctagaatcc aatttaatct gatattcctc taacatatcc tccaatgttt
     8161 tacttcccat tgaattgcta gactgcagaa taatggtgta atccattttt ttatatcgtt
     8221 caatttcttc ttttagaaaa gaaaactgat tgaaaaattc ctgcatagga tattgattga
     8281 attgataaat tttgtcaaat ttgagatttc ctaaaccctt ttgaagatta gagaaaaagg
     8341 tcactggact ttgtttttta tagatttgtt caatatcaga aaaatactgc atatcagaaa
     8401 atgctttact attctgtaat tcttctgtaa agtactgcgc taattctctt tcaaagactt
     8461 catactgatt catcaatttt tgataatcat caaagaatat tggagtatct ttttcaatat
     8521 aatcaaagac agtccatgtc ttatcatagc acaaagataa aaacttccga gaatctgcat
     8581 gactttgctt ttgatgaaaa cttgaaagaa tttcttctag gtatgatttc aaaataggtg
     8641 ataaagtttt tgaaatttgt ttttctaaag ctgactgtcc tcgttgataa tccttttctc
     8701 tcaaaagcat atcactagct ggaaagatag tgagttctgt cttattttct ttcgataatt
     8761 gtgtttctac ttcaaatgac ctgataccat caatttcatc accaaaaaac tcaattcgac
     8821 aaggttctaa ctgggatatt tcaaaaatat ctaaaatatc tcctcgaaga ctaaattcac
     8881 cctgagtttg tacttgagta acttttcgat agccattttc ctttaactga tggataaacg
     8941 cgtgttgagc atattcttca ccaactgaga tttttacaat actatctttg aatgcattgg
     9001 gagacggtaa aatcaatcga cttgctgcga tattacaaac taaaatccct ttcttagatg
     9061 aatcagtcaa aaaacgcaag gcttcaaccc gtgaaataat tttttcctgt gaagacatca
     9121 aaaactccac cataggagca tcatctacca aaaatggata gacgagttcc tcacccaaga
     9181 tagaaataag atcactaaca agtccttctg cttctccata agttgacgtc aataacacaa
     9241 tcctatcttc tttttctaaa ctgcttgcaa ttgcaagagc cttagtagat gttgataaac
     9301 caagtattag ttgtcttttc ttatctgtta aattttgatg ccatttttta atctgatcat
     9361 tttctgagaa taaatctaat aaggtcacca tttatccgtt atacctctgc attgttttct
     9421 caaaattttt ctcttgtaaa tagtagttta cagaatcgtc aactttgtca acagactgta
     9481 aaataccgat ataatcatcc ctgtcaaact tactcaaaac atgatgaaca actgacatac
     9541 catttttagg tcttccaatt ccaatcttaa cacggttaaa gacctgagtt cctatatgtt
     9601 gaataataga cttgatacca ttatgaccac ctgctgagcc ttttgctctt aaacgaattt
     9661 tcccaacttc catgtcaaga tcatcgtaaa tgataagtaa atcgtcaata tccaaaccat
     9721 agtaagttaa taaagcatga actgcttttc cactttcatt cataaaggtc gttggtttaa
     9781 ccagataaat tttttctcca tttaggaaaa aggatgctag gtcagcttga aatatcttat
     9841 cgtgtgtaaa agtgacattc tgtttcttcg ctagttgatc aatcaacata aaaccaacat
     9901 tgtgttttgt ttcaaaatat ttatcccctg gatttcccaa gcctacaagt aatttggtca
     9961 tttatttttc ctttcaaaag ccaaaagggt tggaattttt ttccaaccta attgacacca
    10021 tttattaatt tttagacatt aaagcggaat tccatgatat cgccatcttg aacgatatat
    10081 tcttttcctt cttcacgcaa gcgtccagct tcttttacgg ccttttcaga tccgtatttc
    10141 actagatctt catatgacat ggttactgca cgaataaagc ctttttcaaa gtctgagtgg
    10201 ataataccag ctgcttgagg agccttcata ccacgtttga aagtccaagc gcgaacttct
    10261 ttttcaccag ctgtgaagta agttcccaat ccaagcaagt ggtaagctgc acgcgtcaac
    10321 ttatctacac ctgattctgt caaaccaatg gcttcaagaa actctttttt atcttcatca
    10381 tccaattcag aaatttcttc ctcagcacgc gcagaaataa cgactacttc agcattttct
    10441 gtcgctgcaa attcacgaat ttgtttgaca tagtcgatag agtcaggttc cgaaaccaca
    10501 tcctcatcca cattagctac ataaagaact ggtttagtcg tcaaaaggaa aagacctttg
    10561 acaacctttt gttcctcatc tgtaaattca atggtacgag ctgatttccc atcttctagg
    10621 actggtttaa tcttttgaag aacattgaat tctgctactg attctttatc tttttgcgta
    10681 cgtgccatct tttctacacg cgcatatcgt ttgttcactg attctaagtc agcaagaatc
    10741 aattccagat taatggtatc aatatctgca agcggatcta caaaggcgtc ttcacgtcct
    10801 tgctcgcgca tcacattttc atcatcaaaa gcacgaacta cgtgaacaat cgcatctact
    10861 tcacgaatat tggccaagaa tttattccct agcccctctc cttttgaagc tccttttaca
    10921 atccctgcaa tatctgtaaa ttcaaatgtt gtgggaactg tctttttagg agttatcatt
    10981 tcagttagtt tttgtagacg ttcatctgga acttccacca ttccaacatt tggatcaatc
    11041 gtcgcaaatg ggtagtttgc tgcctctgct cctgcttttg taattgcatt aaatagtgtt
    11101 gatttaccaa cgtttggcaa accaacgata cctgctgtca aagccatatt tctcattctc
    11161 cgttttcatt tcaatcccta atattataac acaaaaaggg ataaagtgct aaccctctaa
    11221 ctaagggttc tcagtcaata attttattca tttttcgctc aaaatcatat cgccccatca
    11281 tgacaacatg ctcacaatta ctgcatttta ttttgatatc tgctcctaca cgtgtaattt
    11341 cccaacgatt agccttttta ccagtcgact tgattgtaca agcgtgtggt tttttcatct
    11401 caacaaaatt tccaacttga tacatactac tctccttttc tttttcgatt atatcataaa
    11461 agaggcgagc caggctcaac ctctttcact taatttgtac gaactggtgt aatgagctgc
    11521 atgaagtctt cgtcagtatc tgctggcaca agagtaaatg gacgaacagc tgagataaag
    11581 ctaatggtca ccttttcgct atttaaagct ttaagagaat caatcaagta agttgggttg
    11641 aaactaatgg tcaaatcttc accagtaacc tgatcagtat cgatttcttc gtttacttta
    11701 ccaacttctg gagagtgaac atgggcgcta acaaccccat ccttaatttc aagtttcaca
    11761 gtaccatttt gagtcgcact tgataaaaga cgggcacgct ccattgactg gcgtaagttt
    11821 accacattaa aagtaatagt agtgttaaag tctgttggaa tcaagcgatc tgtatcagga
    11881 tagtttcctt ctaggagacg agtatagaag ctaatatttt cgcttctaaa gaggatttgg
    11941 ttattggcaa agaaaatctc tacagtttcg atatcatctg taaataccgc tgaaaattcg
    12001 cgtagagaac ggctaggaat tacgacatca aaatcatcac tatttttttc aagagtcaat
    12061 tttttctggc ttaggcgatg agagtctgtt gcaactgttt ttaactcttt gtgttgactc
    12121 aatacgaagt ggacacctgt taaaatcgga cgactctctt gtgtacttgc agcaaaggct
    12181 gtttcattaa taattttctt gagtaatttt gtttcaagta ttaaaggagt gcttgctgaa
    12241 atttcttgga ttcgtggata ttgttcgcta tcttttcctt ttagggtaat ttctgatttg
    12301 ccactggtta aaacaatttg attttgttca atttctttaa aatcaagagt tacatcaggt
    12361 aaactagata ctacattgat aaagaaagaa gcttcaagaa ggatcgaacc taaagaagta
    12421 atcaacaaac cagcatcttc atttttttga gaaataaaat tttcaattga gatttgacca
    12481 tttgaaccaa ttaaagtaat accttcattg gtcacgtcaa tttttactgt tgataaaata
    12541 ggaatggcat ttttagaact aatagctctc ttagtagtat ttaatgcttg tagaaataaa
    12601 tttttattaa ttgaaaaatg aatcatggat tctcctttat ttatttttag tattagaaag
    12661 ataatagtaa taatagagtc tgtgaaatct gtggaaaaca gcctttaaac aagtcctatc
    12721 aagtttttta gcttgtttaa aaaatgtgga taaaaaagat aaaaaactaa aagttatcca
    12781 caaattattt gattttcttt ttgattgatt caatttctaa acgtaaatta tcgtcttgat
    12841 caatcaaaga ttttattttg gcatgggcat gaatgactgt ggtatgatct tttcccccaa
    12901 attccttccc aatttttgga agactattat ctgttagttc tctagataaa tacatggcta
    12961 cttgacgggc caaaacaata ttttgaaggc gtctacttcc cttcatttct ttgatactaa
    13021 caccataaaa gttaccaact tcagtttgga ttttatcaat tgggatgacg agcatttggc
    13081 taacatcttg tttgcgggct ctaatggctt ctgcagcaat atcaatagtg atatccttga
    13141 ttttttttac tctggcaatt aaagtgatgt cgttgatggc tccctcaaga tctcgaacat
    13201 ttgaatcaaa ttgcccagct aggtattcta gagtatcact ttggaaattg tagcctaaat
    13261 gttccgtttt actttgtaaa atggcaatac gtgtttcaaa gtcagggggt gtgatagttt
    13321 gtgtcaatcc ccaactaaaa cgcgtgacaa gcctctcctc gagcccttct agatgttttg
    13381 gactacgatc actcgttagg acaatctgtt tttgcttgtc atgaagggcg ttaaaggtat
    13441 tgaaaaattc ttcctgagtt gcgacttttt ttccgctgag tgactggata tcatcgatta
    13501 acaaaagatc aagactacga taggtctttt taaacttttc catttcccca agtcttaggt
    13561 gatcaagaaa gtcattaata aagctttcgg cagggatata tttaacacgc gcattaggaa
    13621 tattttttag aatttcattt ccaatagcgt ttaataagtg agtcttacca aggcctggtc
    13681 ctccatagat aaaaagaggg ttataggtca gagccaaatc ttcagagaca gctaaagcgg
    13741 ctgatacagc ccaaacattt ccatcccctt gaataaagtt atcaaaggta tacttttctt
    13801 ttaatcccgt atctgaataa ggaatagata ctaactttgg actatagtca taaagagtta
    13861 aatttgtagc ttcttcaact tgtgagctag tcgtatcttg aggtttggtg aaaatatagt
    13921 ggggagttat ttcagcgtca taaatttcaa aaccagctac tacaataata tcttttagtt
    13981 gtttttccca gaccatttcc atttcagagc gaggtagaaa tatagtggca acattttcct
    14041 ctaccttgat aacttcagct tgaatagcat agaaatcata catggatcga gtcagtcttt
    14101 cttgtgcaaa ttctaatata cgattccaaa attgtttttc tttcaatcct ttctcctcct
    14161 ttactattta aaagtttaat actagagata ttttaccata gatagcaaga attttccaca
    14221 agctgtgaaa aataatccac aatgttacca aactttatcc acaggttggg gataaaagaa
    14281 gaaattattg atttattaag ctttttatcg aaaaacatag tggataacct tgtgagataa
    14341 aaaaataaaa gaacagcctt atttcaggct gttgataatt ctactatatt cttcttgatt
    14401 tgaaaaagaa ataatgattt ttccactgtc ttttttagat agtttaattt ctacatctaa
    14461 tccgagtagt tttcttaact gtttttcttc attttgtatg aaatgattag ttttttgctg
    14521 tttcttttgt tttttctctg tcagaagagc ttctaatttc cttacagaaa tatcttcttc
    14581 tataatccgt tgaaagaaat agtcttgttg ttccttattt aacccaacta gggaacgcgc
    14641 atgggcttgt gatagtttgc cattttctac ttctgaaaga atctgttctg gcaaggaaag
    14701 taaacgaatg gagttgctga tatatggacg agacttgccc atcttatctg caatttcagc
    14761 atgggtgaat cctttctcta cgagagattc ataggcgcgt gcttcttcta ttgggtttaa
    14821 attttctctc tgtaaatttt caataatgga ctggaccatc atctcttggt ctgaaatctg
    14881 tttaacaaca gctgggatag accgtagacc agctaaaagt gaagcccgat agcgtctctc
    14941 tcctgcaagg atttcataac caataacagg agattgacga acaataatcg gttgaatgac
    15001 cccattttct ttgatagact gtgctagttc atctagtttt tctctatcaa attcttttcg
    15061 gggttgatag ggattttttt gtatatctgt gatagaaatc atttcaaatt tttccatgat
    15121 tctacactaa cacatctttt ctcttatgta aagctttctt tacatagatg tcaattaaga
    15181 ttctaaatca cctgaactct tgttaagttt gatagaggta gtttcttctt tcccgttacg
    15241 atagtaggtt atcttaatgg tgtctccgat agaatggttg taaagagcac tttgtaagtc
    15301 tgttgatgaa gcaatctctt tgtcatctac ttttgtaatt acatcgtatt tttcaaggtg
    15361 accattggca ggcatattac tttgtaccga acgaacaatt acaccagatg taacattact
    15421 tggaatattg agtcttctga tgtcgcttgt actcacatta gataaattaa ccatctggat
    15481 tcccaaagct ggacgcgtca cttttccgtt tttttctaac tgttcaataa tattgatagc
    15541 atcatttgca ggaattgcga aaccaagacc ttctacagat gttcctccat ttgtagcaat
    15601 tttacttgag gtaattccga taacctgccc ttgaatattg atcagtgggc cgccagagtt
    15661 acctgggtta atagcagtat cagtttggat ggcttttgta gaaatagctt gtccatcttc
    15721 cgattttaag gatacatttc tattgagact ggatacgata ccttgagtga cagtatttgc
    15781 atattcagaa cctaacgggc taccgatggc aatagcagtt tctcctacag ttaacttact
    15841 agaatcacca aactcagcta ctgttgtcac tttttctgaa gagattttga cgacagcaat
    15901 atcagagaaa gtgtcagctc cgacaatttt tccaggtact ttagtcccat ctgacaatcg
    15961 aatatctact ttgctggcgc catttataac gtgattgttg gtgacgatgt aagcttcttt
    16021 atcattcttt ttataaataa ctccagatcc ttcactagag attcgctgag aatctgtgtc
    16081 agtatcatca ttgccaaata cgctattttg tctgtttgcc gaataagtaa taacagaaac
    16141 aacagcatct tttactttgt taacagcctg tgttgttgaa ttttcgttct tataggcagt
    16201 ttgtgtaata gtactattgt tgttagagtt gtttacacta cttttttgag ttagttgagt
    16261 tattgaaaaa ctacccaagg ctccactaaa aaagctaatg acgataacga ctaataattg
    16321 aaaccatttt ttgtaaaatg tttttagatg tttcatattt gcctccatat gtttgaatta
    16381 ctgaaagtat aaactgacta gcttaattat aacttaaaca caaaagtttt acacaaactg
    16441 tggataactc ttttgaaatt gtgattttct taattgaaat ctatttttta ttttgtgaat
    16501 aagatgtgaa aaaatagaga atatgttaga atagagtcat gaaaattaaa gttgtaacag
    16561 ttgggaaact gaaagaaaag tatttaaaag atggtatcgc agagtattca aaacgaattt
    16621 ctagatttgc taagtttgaa atgattgagt tatcagatga aaaaacacca gataaggcca
    16681 gtgaatcaga aaatcaaaag attttagaaa tagaaggtca gagaatttta tcaaaaattg
    16741 ctgaccgtga tttcgttatt gtgttagcca ttgaagggaa aactttcttc tcagaagaat
    16801 ttagtaagca gttagaagaa acttctataa aaggattttc tactcttact tttattattg
    16861 ggggaagttt aggattgtca tcatctgtaa aaaatagagc caatctttct gtcagttttg
    16921 gtcgcataac cttaccccat cagttaatga gactagttct tgttgaacaa atctatcgcg
    16981 cttttacgat tcagcaggga ttcccctacc ataaatagaa aattgacttt taattgaatt
    17041 tttggtagaa taattgtatt aggtctcata gctcagctgg atagagcatt cgccttctaa
    17101 gcgaacggtc gcaggttcga atcctgctgg gatcaatata atagcaaagc tgggaatttt
    17161 cccggctttt ttcttaaaaa agtacacttt gggagaaaaa aatgacagtt gagagaattt
    17221 tatctaaaac gaaattccat tttgtataat ggtttttgta agttagctta caagaaaaaa
    17281 cattttagga gattttatta tgaaaaacac agttaaattg gaacagtttg tagctttgaa
    17341 ggaaaaagac ttacaaaaga ttaaaggtgg ggagatgagg ttgtcaaaat tcttccgtga
    17401 ttttatttta caaagaaaaa agtaatgaaa taaggggaaa gagtaatgga tttatttgga
    17461 tttgggacgg ttattgttca ttttttaatt attagtcaca gttaccattt tatttgtaaa
    17521 ggtcaaataa atagaaaaga attattcgtt tttggtgctt atacattact aacagaaata
    17581 gtatttgatt ttcccttata tattctatat ttagatgggt tagggattga aagattttta
    17641 tttcctttgg gattatattc ctattttcga tggatgaaac agtatgagag ggatagagga
    17701 ctattcctaa gtttactact atctctttta tatgagagca ctcataactt tctgtccgta
    17761 actttctcct ctataacagg agataatttt gttttacaat atcatttccc attctttttc
    17821 gttgtgacgg tgttaaccta ttttgttaca ttaaaaatca tttactattt ccatttggaa
    17881 ctagcctatt ttgatgagga ctacctttat cctttcttga aaaaagtatt ttttgcttta
    17941 ctattgctac atattgtatc tttcgtttca gatatggtaa gtacgattaa acatttgaat
    18001 agttttggaa gtattttgtc atctattgtc tttatctctc tccttttgac cttctttgca
    18061 atgaattctc ataaagttca aatggagaaa gagattgctt tgaagcagaa gaaatttgaa
    18121 cagaaacatt tacagaatta cacagatgaa attgttggtc tgtataatga aatccgtggt
    18181 tttcgacatg attatgctgg aatgcttgtc agcatgcaga tggcaattga cagtggtaat
    18241 ttacaggaaa ttgacagaat ttacaatgaa gttttagtca aagcaaatca taaattgcgt
    18301 tcagataagt acacttactt tgatttgaac aacatagaag actcagcttt acgaagtttg
    18361 gttgctcagt caattgtcta tgctcgaaat aatggtgtag agtttacact ggaagtaaaa
    18421 gatacgatta ccaagcttcc aattgaacta ttggatttgg ttcgtatcat gagcgtttta
    18481 ttgaataatg ctgtcgaagg atcggctgat agctataaaa agcagatgga agtagcagtt
    18541 attaagatgg aaactgaaac agttattgtg attcagaatt catgtaaaat gacgatgact
    18601 ccttcaggag atctatttgc cttaggattc tccactaagg gaagaaatcg cggagtcgga
    18661 ttaaataatg tgaaagaact actagataag tacaacaata ttattttaga aacagagatg
    18721 gaaggcagta catttagaca aatcattaga tttaagaggg aatttgaatg aaagttttaa
    18781 ttttagaaga tgttattgaa catcaagtga gactagagag aatattggat gaaatttcga
    18841 aagaatcgaa tattccaata tcatacaaga caacgggaaa agtccgtgaa tttgaagaat
    18901 acattgaaaa tgatgaagta aatcagcttt atttcctaga tatcgatatt catggaattg
    18961 agaaaaaggg atttgaagtg gctcagctca ttcgtcatta caatccttac gctattatcg
    19021 tctttatcac tagtcgatca gagtttgcga ctctaacata taaataccag gtatcagccc
    19081 tagattttgt tgataaggat atcaatgatg agatgtttaa gaagagaatt gagcaaaata
    19141 tcttctacac gaagagtatg ttacttgaaa atgaagatgt tgtagattat ttcgactaca
    19201 attacaaggg aaatgattta aaaattcctt accatgatat tttgtatatt gaaacaacag
    19261 gggtatctca taaattgcgc attattggta agaattttgc aaaagagttt tatggtacca
    19321 tgacagatat tcaggaaaag gacaaacata ctcagcgatt ttattctcct cacaagtcat
    19381 ttttggtaaa tataggcaat atcagagaaa ttgatcgaaa aaacttagaa attgttttct
    19441 atgaagacca tcgttgtcct atttcaagat taaaaattag aaaattaaaa gatattttag
    19501 agaaaaaatc tcaaaagtga ttgacaatta gcaagaaatt gatataatgg ttatatctgc
    19561 tacagataga aggtccgttg gtcaaggggt taagacaccg ccttttcacg gcggtaacac
    19621 gggttcgaat cccgtacgga ctattttatc cgccatagct cagttggtag tagcgcatga
    19681 ctgttaatca tgatgtcgta ggttcgagtc ctactggcgg agtatagata aaagggaaca
    19741 cagctgtgtt cctctttttg tatcaatttg tatcaccaag cattttcata aggaagtctg
    19801 ttatttcttg agaactttct ttttttccat gtgcaatcca agtttggcag acaccaaaaa
    19861 gtgcatgagt tagatagatg ctactatatt ctaattcggt ggtatttaga ttcagttgca
    19921 taaatcgctt ttgtaaatct gtactaagca tgatatgaag tttatttcgt aagaaatttt
    19981 ggatttcttt agtcccattt tcagaaagaa gggcagccag aagtggttct gactctagat
    20041 attcaaaaac ttctaaaata gcgtctcttt tgtgatgagc atgtttttga aaaatatatt
    20101 caaatgtatg gaatagcttg ctttgatagt gctcaatcat atcatactta tccttatagt
    20161 gagtatagaa gctggaacga ctaattccgg ctttttctac taatttgaca gtagaaattt
    20221 tatcaaatgg ctgttccatc agtaattgta ccatagcatt ttcaatagtt cgctttgttt
    20281 ttaagcgttt gttactttct tgcatatttc ctccttgtaa acaaattaga ctatatgtct
    20341 aaaaatagat tttttatctt gtaatttaga ttttttaatg tataatctat tatatcaaaa
    20401 ttttagacaa tatgtttaaa aaaggagaaa ctaagtttaa agaatggaaa gcaatttaaa
    20461 aaaaaccaac ctttattatt gtcatgatcg ggatttctct tattccagat ctgtacaata
    20521 tcatattttt gtcatcaatg tgggatccat atgggcaatt gtctgactta cctgtggcag
    20581 ttgtaaataa tgataaagag gcttcctata atggtaatac tatggcaata ggaaaagaca
    20641 tggtgtccaa tttaaaagaa aataaaacct tggattttca ttttgtagat gaagaggaag
    20701 gaaagaaggg attggaagat ggcgattact atatggtagt gactttacca agtgatttat
    20761 ctgaaaaaac aactacatta tccaatattc aatcgacagc agcttatcaa tcattgacaa
    20821 gtgagcaaca aactgagata agtgattctg tatctcaaaa ttcaactgat agtattcaat
    20881 cggctcagtc aattgtagct ttagtacaag atttacaggg aagtttagaa aacttacaaa
    20941 atcaatcttc taatctttcg actttaaaaa atcaatctaa tcaagtatca cctattactt
    21001 ctacttcttt gataggattg tcaagtggat taacagagat acaaggagat gttactagca
    21061 aattagttcc tgccagtcag tcgattgcat caggtgtaaa cgcatatact acaggtgttg
    21121 ataaagtttc tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg acaggtagtt
    21181 tggataaact agtttcaggc tcaaacacct tgacacaaaa atcttctaga ttgacagcag
    21241 gagttggtta attacaatca ggatctgggc aattagcaga caaatccagt cagttacttt
    21301 caggtgcttc tccattagag aatagagcta ataaattggc agatggatct aggaaactag
    21361 cagaaggtgg aacaaagtta acttctggat tggaagattt acagacagga cttgcttctt
    21421 taggacaagg actaggtaat gctagtgatc aactcaaatc agtatcaaca gaatctaaaa
    21481 atgcagagat tttgtcaaat ccactcaatc tttcaaaaac agacaatgat caagttcctg
    21541 taaatggaat cgcaatagct ccttatatga tatcagttgc tctttttttt gcagcaatat
    21601 caacaaatat gatatttgcg aaattgcctt caggacgtca tccagagagc cgttgggctt
    21661 ggttgaaatc ttgagctgaa ataaatggta ttatagctgt tttggcagga attttggtat
    21721 atggaggagt tcagcttatt ggtttaactg ctaatcatga gatgagaata tttattctca
    21781 tcatcctaac aagtttagta ttcatgtcta tggtgaccac tttagcaacg tggaatagcc
    21841 gtataggagc ttttttctca cttattttgc ttttactaca gttagcatca agtgcaggta
    21901 cttatccact tgctttgaca aatgatttct ttagatctat taatccctgg ttaccaatga
    21961 gctattcagt ttcgggatta cgacaaacaa tctctatcaa caagtcattt tcctagctgt
    22021 catactagct ctatttactg gtttaggtat gctagcctat caacataaga aaatggaaga
    22081 agattaaaaa aatcgaccga ttaactggtc gattttttat gccttagatg actttcgtct
    22141 gtgattatag attccaaata gtaagagaga agtaaaggaa cagattgctc cagtaataaa
    22201 accattggga atgaaggaaa gtgtaatagt tcctttcccc ttgggaatgt caactttcat
    22261 aaatccagtt tgagcttgtt taatttctat tttcttacca tcttggtagg cagaccaacc
    22321 tttgtcataa ggaatggtga agaaaataga tgtatcttgt tggacatcat atgtagcaaa
    22381 aaccttgttt ttagaagttg atactgtgac aggttgttct ttaatttttt gaattgcctc
    22441 ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat tcaaatgata cttgtgaatt
    22501 tccagggaaa ctaacattga tattgaaagt ttttttctct ttagtatatc ctagattaaa
    22561 gaaggagaag acattatcag ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac
    22621 cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa gagagataaa cttggctgtt
    22681 ttctggaact tcaatttgat actggattgc tgcatcttca tttgaagaac ttgtgacact
    22741 aatcaaatca ttagtatttt ctattttttc tgttttttca taaggtattg gagaaaaata
    22801 atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca aggtatgttc
    22861 attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa gagagtattg
    22921 attttcatat agggtaagat tatctttttg atagatatct ttaaagccat acttatcaat
    22981 aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa tactattatt
    23041 tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat ctaaagtaga
    23101 gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt tgaatttcat
    23161 actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat ttccaatata
    23221 tgttgagaaa gattccatag ctaggatatc tcgactataa gcacttcgag aagcaaatcc
    23281 ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt caaccagtat
    23341 aaataaagag attagaatgg caaatagatt cacagatata aactttttga taactgcaag
    23401 gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca aatctgttaa
    23461 aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta caagaaaaag
    23521 cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt ctgctgctgt
    23581 gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt ttggagtatg
    23641 catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta gaaatgcaaa
    23701 gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa aaaataaaat
    23761 ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat actttgttgt
    23821 gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac tttcagtttg
    23881 aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata gagtgggaag
    23941 agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat caagaacaga
    24001 tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa taagaaacaa
    24061 tactgtcata tatccaaaat aataattttg aataaataag attgacagac ttgtaaagta
    24121 caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta aaggaatcaa
    24181 gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac tcatcagagc
    24241 ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca atttattcaa
    24301 actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca gatagacagc
    24361 atctggcatg ttcgttagat caaaaaagta aactagaggc gcgagaaaac tacccaagta
    24421 ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt aaaacagact
    24481 actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt gatgaaagcc
    24541 atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata gatatactcc
    24601 agacataatc actacaggaa tgatgagaga aataaaatag gttcgatatg tttttaaaaa
    24661 tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca actgagtttt
    24721 gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct gcattttcta
    24781 ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat aagacaatga
    24841 tatggttagc caaagtttga ataaattcgt ggtcatggct agcaaagatg attgattctt
    24901 taaagttttt caatccatca ttcaagcttg agatagattc caagtccaag tgatttgttg
    24961 gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc atgacacgaa
    25021 ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca gagaagagca
    25081 tacggccgag gaagccacgt aggaaagtat tgtcatcttc ttctttactt gcgaattgac
    25141 gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct tttggtaggt
    25201 aagattgact agttgtaact ccccacttga cagttccttc atagtcaata tctcccatga
    25261 ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct gtcttatcat
    25321 ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc tttacagtta
    25381 gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag ttgataaatg
    25441 gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc attttcttac
    25501 gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg aattcttgca
    25561 attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta gcagcaagct
    25621 cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt ccaaagtcaa
    25681 ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat actacgataa
    25741 ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg atatccaaac
    25801 cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct ttggcgagga
    25861 gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt aattcttctg
    25921 gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa cctccaagtt
    25981 cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag aaatcttcct
    26041 tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt cccatgataa
    26101 cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga acagagagac
    26161 gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca gctaaaattt
    26221 ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta tttccttctg
    26281 taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt gaaacatcag
    26341 atactgtaag caatattttt ctcctatatg tgtaatatat ttattctact agaaaataca
    26401 gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt atcctttaca
    26461 caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt cattaaaaaa
    26521 atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc attattttaa
    26581 caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt ctcaaaaatc
    26641 gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct gaccaacaag
    26701 ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga aatgtggctt
    26761 tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt caaagccaga
    26821 ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta gcacgtttgg
    26881 agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa agcattccga
    26941 caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc aaggctaatt
    27001 atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa attgttcgtt
    27061 cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt tatccagaaa
    27121 atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct aaatcactaa
    27181 ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta atgagtatgt
    27241 atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga aatatggttt
    27301 tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct gatatgaaag
    27361 aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta cttgaaatat
    27421 tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag gatatgggag
    27481 aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg ggtcaaaccc
    27541 tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat tttacaagaa
    27601 actatcattt ctatctcgaa gaaaagatag ttttttattt acccctgtaa catttgacaa
    27661 atttttatag aatggtatga tagatacaat ataaaaagag tcaagctcaa aaagaaagaa
    27721 aagaggaaac ttcgaatgtc taattgggac actaaatttt tgaaaaaagg ttttaccttt
    27781 gatgatgtat tgcttattcc agctgaaagt catgtgttgc ctaacgatgc agatttaaca
    27841 actaaattgg cagataattt gactttaaat atcccaatta ttaccgctgc catggacaca
    27901 gttacagaga gtcaaatggc cattgctatt gctcgtgcag gtggtctcgg agttatccat
    27961 aaaaacatgt caattgctca acaagcagac gaggttcgta aggtaaaacg ttctgaaaat
    28021 ggagttatta ttgatccgtt cttcttgacg cctgaacata caattgctga agcagatgag
    28081 cttatgggtc gttaccgcat cagtggtgtt ccagttgttg aaacacttga aaatcgtaaa
    28141 ttggttggta ttttgacaaa ccgagatctt cgttttattt cagattataa tcaaccaatt
    28201 tcaaaccata tgactagtga aaatcttgtt actgctcctg tgggtacgga tcttgcaacg
    28261 gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc cgttggtcga tgaagaaggc
    28321 agtctttctg gtttgatcac tatcaaagat attgaaaaag ttattgagtt tccaaatgcg
    28381 gctaaagatg aatttggtcg tcttctagtt gcaggtgcag taggtgttac ttcagataca
    28441 tttgaacgtg cagaggctct ttttgaggca ggagcggatg cgattgttat tgatactgca
    28501 catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga ttcgtgctca tttcccagat
    28561 cggactttga ttgctggaaa tattgctact gctgaaggtg cacgtgccct ttatgaagcg
    28621 ggtgtagacg ttgttaaggt tggtattgga ccaggttcta tctgtactac tcgtgtgatt
    28681 gctggtgttg gtgttccgca agtaacagct atctacgatg ctgcagctgt tgcgcgcgaa
    28741 tatggtaaaa cgattattgc tgacggtggg atcaagtatt ctggagatat tgtaaaagca
    28801 cttgctgcag gtggaaatgc tgttatgctt ggatctatgt ttgctggaac tgatgaagct
    28861 ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga cttaccgtgg tatgggatca
    28921 attgctgcta tgaagaaagg ttcaagcgac cgttatttcc aaggttctgt caatgaagca
    28981 aacaagctcg ttccagaagg aattgaaggt cgtgttgctt ataaaggagc ggcagctgat
    29041 attgttttcc aaatgattgg tggtattcgc tctggtatgg gttactgtgg tgcagctaac
    29101 cttaaagaac tacacgataa tgctcaattt attgaaatgt ctggtgctgg tttgaaagaa
    29161 agccatcctc atgatgtgca aattactaat gaggcaccaa attattctat gtaaaaaaca
    29221 atgaaaagaa ctccagtgaa aacaggagtt cttttacaat gttgtcaatt tccatttaca
    29281 gaagctttac catcctgaat agtgaagata cttagatttt ctggcagatt ttgaagatgg
    29341 tctaagcttg ttgttgtgat aaaggtttgg attgattgag aaatcgtttc taataatttt
    29401 aactgtctag tgttgtcaag ttcactcatc acatcgtcaa gcagtaatat aggagattct
    29461 gtggtaatgc tttccattaa ttcgatttct gctaatttta tcgagaggac gagactacga
    29521 tgttgacctt ggcttccgaa actagcatcc atcccattta tataaaaaga aatgtcatct
    29581 cgatgaggac cgacaccagt attcttttta aataaatctc tggatctact tttttctaaa
    29641 gcaattttga aagattcgga taagttttgt ttgtcagtta tattgacaga agattgatag
    29701 gatattgaca actcttcgat ctgattagag agttcaaaat gtttcttacg cccaaatgat
    29761 tctagttttt ttatgaaatc taagcggtga ttcattacac gacatccata atcaactagc
    29821 tgatcatcta acacagaaag gaatgtttca tctatttttt gagctgattt taggtaagtg
    29881 tttctttgct ttaggatgtg gttataattg gttaagtcag ataaatagat tggcttaatt
    29941 tgcccaagtt ccatatcaat gaattttcgt cgaatcgaag gtgctccttt aattagttgt
    30001 aaatcttcag gagcaaataa gacaacattc atgtgtccta cataatctga aaggcgtgcc
    30061 tgttttaagt gattaacttt tgttacacgg cctttttgtg ttagttcgat ttctagggga
    30121 atggatccag tttttttctg aacgagacct gaaagatgaa gttgttcctc atcaaaatga
    30181 atgagatttt tatctgttcg agttcgatga ctacgcgtta aggctaaaaa atagatagcc
    30241 tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa agacattcaa tttaggatta
    30301 aagtctattt tcgtttcttt gtaattacga aaagtcttga gagatagatg ttgtagccac
    30361 atgattatct accagggaat cgtggagctt gttggctttt aggtgatgaa gcaggtttcg
    30421 atttgtcttt tttaactccc ttattcatct ttttgacaag tttagcgatc cgttcttttt
    30481 caactttatc agcttggtat tcatcttgtt cttcagaagt aggttgtgtc aacaagatgt
    30541 caatgttcat gtcagggatg tcaactttat cgccaatacg aagttttttt ccacgacgac
    30601 tctctaattc cctattaaag taaacagaat gttcagagag aaatgattta atagctcctc
    30661 cgctatgtgt aattccaagt tctttgagta gtgcttggag ggtaataaat tcttcaaata
    30721 atttgtattc cataattcac ctcaatcttt ggtattatac catattttcc taaaaatagt
    30781 gagagagaca gcgagaaatg taagcgattt ttatttcaaa agtgttacag ggaacaagaa
    30841 aatttcaggt tttcgtgata taatagaagt ctgtatataa ggaggtaaat catggagtta
    30901 gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt ttaaaacaaa caaaattacc
    30961 gtgcgtttta ccgctccatt atcccttgat acgattgcag gtcacatgtt gagtgcaagt
    31021 atgctagaga ctgctaatca gatgtacccc acttctcaag atttgaggag acacttggcc
    31081 agtctatacg gtacagatat gtcaaccaat tgtttcagaa gagggcaaag ccacattata
    31141 gaattgacat ttacctatgt tcgtgatgag tttttaagta ggaaaaacgt gctaacctct
    31201 cagattttgg aacttgtaaa agaaactctt ttttcacccg cagtagttga taatgggttt
    31261 gatccggcct tatttgaaat tgagaaaaaa caattgctag caagtttagc agctgatatg
    31321 gatgattctt tttattttgc acataaagaa ttggataaat tgttttttca tgatgaacgt
    31381 cttcaattgg aatatagtga tttacgaaat cgtattttag ctgaaactcc acaaagttct
    31441 tattcttgtt tccaagaatt tttagccaat gatcgaatag atttcttttt cctaggtgat
    31501 tttaatgagg ttgaaattca aaatgtatta gaatcatttg gctttaaagg tcgaaaagga
    31561 gatgtgaagg ttcagtattg tcaaccttat tctaatatcc ttcaggaagg tatggttcgg
    31621 aaaaatgtgg gacaatccat tttggaatta ggttatcatt accgttctaa atatggtgat
    31681 gagcaacatt tacccatgat tgtaatgaat ggtttacttg gtggatttgc tcactctaag
    31741 ctctttacaa atgtccgtga aaatgctgga ttagcttata ccatttcaag tgagcttgat
    31801 ttatttagtg gattcttgag gatgtatgct ggtatcaatc gagaaaatcg taaccaggct
    31861 cgtaaaatga tgaataatca actgcttgat ttaaaaaaag gttattttac agagtttgag
    31921 ttaaatcaga ccaaggaaat gattcgttgg tcgttgttac tttctcaaga taatcaatct
    31981 tcattgattg aacgtgctta tcaaaatgcc ttatttggaa aatcttcagc agactttaaa
    32041 agttggattg cagagcttga acaaattgac aaagatgcta tttgtagagt agctaataat
    32101 gtgaaactac aagcgattta ctttatggaa ggaatagaat gacaaaggtt gtttttgaag
    32161 aaaaatacta tccagctgta aaagaaaagg tttatcgaac tcgtttggcc aacggattga
    32221 cagttgctct tttgcctaaa aaggaattta aagaggttta cgggagtgtc actgtacagt
    32281 ttggttcggt agatacgttt gtcacagaag ttgacggata tgtaaaacaa tatcctggag
    32341 gaattgctca ttttcttgaa cataaattat ttgagagaga agattctagt gatttgatgt
    32401 cggcttttac gagtctaggt gcagatagta atgcctttac aagctttaca aaaacaaact
    32461 atcttttttc agcaacggat tattttttag aaaatttaga tttacttgat gaattggtaa
    32521 catcagcaca ctttactgaa gcttccattc tgacagagca ggatattatt cagcaagaac
    32581 gagaaatgta ccaagatgat ccagattcgt gtttattctt ttcaacttta gcgaatttgt
    32641 atcctggtac acctttagca actgatatag ttggaagtga ggagtccatt tcccaaatca
    32701 atctaactaa tttgcaagaa aattttacaa agttttacaa acctgtaaac atgtctctgt
    32761 ttttagttgg taattttgat gtggagcgag tacaggacta ttttgaaagc aaagaactga
    32821 aagattcaga ttttcaggaa gtagcaagag aaaagttgtt tttacagcct gtaaagccaa
    32881 cagatagtat gagaatggaa gtatcttctc ccaaactagc gattggagtt agaggtaagc
    32941 gagaagtttc tgaagcggat tgctatcgac atcatatttt attaaaatta ttgtttgcaa
    33001 tgatgtttgg ttggacttcg gatcgttttc aaaaatgtta tgaatcaggt aaaattgatg
    33061 cgtccttatc tctggaagtt gaaataacaa gtcgctttca ttttgtcatg ttgacaatag
    33121 atacgaaaga gccagttgct ttgtctcatc aatttaggaa ggctattcgt aattttacaa
    33181 aggatttaga tattacagag gaacatttag atattatcaa aagagagatg tttggcgaat
    33241 ttttcagtag catgaactct cttgaattta ttgcaacgca atatgatgct tttgaaaatg
    33301 gtgagacaat ttttgatttg ccgaaaattt tacaggaaat tactttagag gatgtccttg
    33361 atgctggaca tcatttaata gatgatggtg acatagttga ttttacaata ttcccatcgt
    33421 agtaacctat cataatagac actagaaaga agggatgaca agtatgagaa aaaaaacaat
    33481 tggagaggtt ttacgattag ctagaatcaa tcagggattg agtttagatg aattgcagaa
    33541 aaagacagaa atccagttag atatgttgga agcaatggaa gcagacgatt tcgatcaact
    33601 tccaagtcct ttttacacgc gttctttctt gaaaaaatat gcatgggctg ttgagttaga
    33661 tgaccaaatt gttttggatg cttatgattc tgggagtatg attacttatg aggaagtaga
    33721 tgttgatgaa gatgagttga caggtcgtag acgttcaagt aagaaaaaga agaaaaaaac
    33781 atcattttta cctttatttt attttatcct ttttgcttta tcgattttaa tttttgtgac
    33841 ttattatgtt tggaactata ttcaaactca accagaggag ccttctcttt ctaattacag
    33901 tgtggttcaa tcaacaagtt caactagctc tgttccccac tcctcaagta gtagttcttc
    33961 tagtatagaa tcagctataa gtgtatcagg cgaaggaaat catgtagaaa tcgcttataa
    34021 gacaagtaag gaaacagtta aattgcaatt ggcagtttca gatgttacaa gttgggtcag
    34081 tgtttcagaa agcgaacttg agggcggtgt aaccttatcg ccaaagaaga aaagtgcaga
    34141 agcaacagtt gcaactaaaa gtcctgtaac aattacgtta ggtgttgtaa aaggtgttga
    34201 tttgacagta gataatcaga ctgttgattt atcgaaatta acagctcaga ctggacaaat
    34261 cactgtaacc tttactaaaa attaaggaaa aacgaatgaa aaaagaacaa attcccaatc
    34321 tcttaacaat aggtcgaatt ctctttatac ctatttttat ctttatttta acgataggaa
    34381 attcgataga gagtcatata gttgcagcta ttatctttgc tgttgccagt attaccgact
    34441 atttagatgg atatttagct cgtaaatgga atgtggtcag taattttggt aaatttgcag
    34501 atcctatggc ggataagtta ctagttatgt cggcttttat tatgttgatt gagttaggta
    34561 tggctccggc ttggattgtt gcagtgatta tctgtcgtga gttagctgtg acaggtttaa
    34621 ggcttttatt ggttgaaact ggtggaacaa ttttagcagc agcaatgcct ggaaaaatta
    34681 aaacttttag tcagatgttt gctattattt tcttgctatt acattggact ttgcttggtc
    34741 aagttctact ttatgtagcc ttatttttca ctatctactc tggctatgac tatttcaagg
    34801 gtagtgccta tgtatttaaa gggacatttg gttcgaaatg aaatcaataa ttgatgtaaa
    34861 aaatctttct tttcgctata aagaaaatca gaactactac gatgtgaagg atattacgtt
    34921 tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat aatggtagtg gtaaatcaac
    34981 gacggttcga ttaattgatg gcttactgga agcagaatcc ggagagattg taattgatgg
    35041 ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt caaatcggta tggtttttca
    35101 aaatccagac aatcaatttg ttggagcgac tgttgaagat gatgttgctt ttggtttgga
    35161 aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg gaagaagctc tggctttagt
    35221 tggcatgttg gactttaaaa agagagagcc agcgcgtcta tcaggtggcc aaaagcaacg
    35281 tgtggccatt gcaggtgttg tagccctaag accagctatt ttaatcttag atgaagcaac
    35341 gagtatgttg gatcctgagg ggcgtagaga acttattggg acagtaaaag gaattcgaaa
    35401 agactatgat atgacggtca tttctattac ccatgatttg gaagaagtcg ccatgagtga
    35461 tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact agtagtccaa gggagctttt
    35521 ctctcgaaat gatttagatc aaattggatt agacgatcct tttgctaatc aattaaaaaa
    35581 atctttgagc cagaatggct atgatttacc tgaaaattat ttgacagaaa gtgagctaga
    35641 ggataagcta tgggaattgc tctagaaaat gtgaatttta tatatcaaga aggtactccc
    35701 ttagcttcag cagctttgtc ggatgtttct ttgacgattg aagatggctc ttatacagct
    35761 ttaattgggc acacaggtag tggtaaatca actattttac aactcttaaa tggtttattg
    35821 gtgccaagtc aagggagtgt gagggttttt gataccttaa tcacctcgac ttctaaaaat
    35881 aaagatattc gtcaaattag aaaacaggtt ggcttggtat ttcagtttgc tgaaaatcag
    35941 atttttgaag aaacggtttt gaaggacgtt gcttttggac cgcaaaattt tggagtttct
    36001 gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc tggttggaat tgatgaatca
    36061 ctttttgatc gtagtccgtt tgagctgtca gggggacaaa tgagacgtgt tgccattgca
    36121 ggcatacttg ccatggagcc atctatatta gtcttagatg agccaacagc tggtctagat
    36181 cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac tccaccagtc agggatgacc
    36241 atcgtcttgg taacgcattt gatggatgat gttgctgaat atgctaatca agtctatgta
    36301 atggaaaagg gacgtttagt aaaggggggc aaaccaagtg atgtctttca agacgttgtt
    36361 tttatggaag aagttcagtt gggagtacct aaaattacgg ccttttgtaa acgattggct
    36421 gatagaggcg tgtcatttaa acgattaccg attaagatag aggagttcaa ggagtcgcta
    36481 aatggatagt atgattttgg ggcgttatat cccaggggat tcgattgttc accgattgga
    36541 tccacgtagc aaattgcttg ctatgatgct actgattttg attgtgtttt gggctaataa
    36601 ccccttgacg aatctgattc tttttatagc gacagggata tttattgcct tgtcaggagt
    36661 atctctttca ttttttattc agggcttgaa gtctatgttt ttcttgattg ccttcacaac
    36721 tatttttcaa ctatttttca tttctaatgg gaatgtttta tttgagtttt cgtttgtgag
    36781 aatcacggat tatgctttgc aacaagctgg gattattttt tgtcgctttg tattgattat
    36841 tttcttttca actttgttaa ccttaacaac catgccttta agtttggcat cagctgtcga
    36901 agctttatta gcacctttaa agcgtgtgaa agttccagtt catgaaattg gattgatgct
    36961 gtctatgagt ttgcgttttg tcccaacctt gatggatgat acgactcgga ttatgaatgc
    37021 acagaaagct cgtggagtgg attttggaga aggaagcatc gttcaaaaag taaaggcgat
    37081 gattcccatt ttgattcctc tttttgcgac aagtttaaaa cgtgcagatt ccttggctat
    37141 cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga agtcaatacc gacaattgaa
    37201 atggactcta aaggatacgc tgaccattct tgttattctc gtacttggtt gttgtttatt
    37261 tttcttaaaa tcttagtagc tttcaggaat tgataaaaag ttactgtaac agtttttgat
    37321 ataaaggtag ggatatgaac cgttttaaaa aatcaaaata tgtcattatt gtttttgtca
    37381 ctgttctgct tgtgtcagct ctcttagcga cgacttattc aagtacaatt gtgacaaaat
    37441 taggagatgg aatctcattg gttgatagag ttgtacaaaa accttttcag tggtttgatt
    37501 ctgtcaaatc agatttggct catttgacac gaacatataa tgaaaatgaa agtttgaaga
    37561 aacagcttta ccaattagaa gttaaatcaa atgaggtgga aagtttaaag acagaaaatg
    37621 aacaactgcg ccaattgctt gatatgaagt ctaaattgca agccacaaag actttagcag
    37681 cagatgttat tatgcgttct ccggtatctt ggaagcagga gttgacctta gatgcaggta
    37741 gatcaaaagg tgcttctgag aacatgttag ctattgcaaa tggtggcttg attgggagtg
    37801 tttcaaaagt agaggagaac tctactatag tcaaccttct gacaaatacg gaaaatgctg
    37861 ataagatttc tgttaaaatt caacatggct ctactacaat ttatggaatt attattggct
    37921 atgacaagga aaatgacgtt cttaaaatta gccaattaaa tagtaatagc gatattagtg
    37981 cgggagataa ggtgactact ggtggattag gaaactttaa cgttgctgat attcctgttg
    38041 gtgaagtggt tgccacaacg catagtacag actatttgac acgagaagta actgttaaat
    38101 tgagtgcaga tactcataat gtagatgtga tagaattagt ggggaattca taatgagaca
    38161 gttgaagcga gttggagtat ttttattgct tcctttcttt gttctaattg acgcccatat
    38221 tagccagctt ctgggctcat ttttccccca tgtacatttg gctagtcatt ttctttttct
    38281 atttctctta tttgagacga tagaagtatc agagtatctc tacctagtct attgttttgt
    38341 tataggcttg gtttatgatg tttacttttt ccatctaata gggattacaa ctctcttatt
    38401 tatcttattg ggagccttcc ttcataaatt gaatagtgtt attttgttga atcgttggac
    38461 aagaatgcta gctatgattg tgctgacatt cctgtttgaa atgggtagtt atcttttggc
    38521 ttttatggta gggttgacag tagatagcat gtcgattttt atagtctata gcttggtacc
    38581 gacgatgatt ttaaattttt tatggattac tgtttttcaa tttatttttg aaaaatatta
    38641 tctataagaa cgacatataa atgtaacaaa ggcgtaatat ttattaggcc tttttttggt
    38701 atactagtat tgtctttaaa agaaggagta tctacgtaat atgaagaaaa aaatcttagc
    38761 gtcactttta ttaagtacag taatggtttc tcaagtagct gttttaacaa ctgcgcatgc
    38821 agaaacgact gatgacaaaa ttgctgctca agataataaa attagtaact taacagcaca
    38881 acaacaagaa gcccaaaaac aagttgacca aattcaggag caagtatcag ctattcaagc
    38941 tgagcagtct aacttgcaag ctgaaaatga tagattacaa gcagaatcta agaaactcga
    39001 gggtgagatt acagaacttt ctaaaaacat tgtttctcgt aaccaatcgt tggaaaaaca
    39061 agctcgtagt gctcaaacaa atggagccgt aactagctat atcaatacca ttgtaaactc
    39121 aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg agtgaaatcg tatctgcaaa
    39181 caacaaaatg ttagaacaac aaaaggcaga taaaaaagct atttctgaaa aacaagtagc
    39241 aaataatgat gctatcaata ctgtaattgc taatcaacaa aaattggctg atgatgctca
    39301 agcattgact acgaaacagg cagaactaaa agctgctgaa ttaagtcttg ctgctgagaa
    39361 agcgacagct gaaggggaaa aagcaagtct attagagcaa aaagcagcag ctgaggcaga
    39421 ggctcgtgca gctgcggtag cagaagcagc ttataaagaa aaacgagcta gccaacaaca
    39481 atcagtactt gcttcagcaa acactaactt aacagctcaa gtgcaagcag tatctgaatc
    39541 tgcagcagca cctgtccgtg caaaagttcg tccaacatac agtacaaacg cttcaagtta
    39601 tccaattgga gaatgtacat ggggagtaaa aacattggca ccttgggctg gagactactg
    39661 gggtaatgga gcacagtggg ctacaagtgc agcagcagca ggtttccgta caggttcaac
    39721 acctcaagtt ggagcaattg catgttggaa tgatggtgga tatggtcacg tagcggttgt
    39781 tacagctgtt gaatcaacaa cacgtatcca agtatcagaa tcaaattatg caggtaatcg
    39841 tacaattgga aatcaccgtg gatggttcaa tccaacaaca acttctgaag gttttgttac
    39901 atatatttat gcagattaat ttacagaggg actcgaatag agccctcttt tcaggtttta
    39961 ccgtgacaat ccctattaaa aattatatca aaatagcttg aaaatattgg aaaagtatgg
    40021 tagaatgaaa attgtcgtgt gaacgataat actcattctt gatgaattgt gaagcagttg
    40081 cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa aaaacaaaaa ggagaaatac
    40141 tcatggcagt aatttcaatg aaacaacttc ttgaggctgg tgtacacttt ggtcaccaaa
    40201 ctcgtcgctg gaatcctaag atggctaagt acatctttac tgaacgtaac ggaatccacg
    40261 ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc atacgacttc atgcgtgatg
    40321 cagcagctaa cgatgcagtt gtattgttcg ttggtactaa gaaacaagca gctgatgcag
    40381 ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa ccaccgttgg ttgggtggaa
    40441 ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg tttgaaagaa attaaacgta
    40501 tggaagaaga tggaactttc gaagttcttc ctaagaaaga agttgcactt cttaacaaac
    40561 aacgtgcgcg tcttgaaaaa ttcttgggcg gtatcgaaga tatgcctcgt atcccagatg
    40621 tgatgtacgt agttgaccca cataaagagc aaatcgctgt taaagaagct aaaaaattgg
    40681 gaatcccagt tgtagcgatg gttgacacca atactgatcc agatgatatc gatgtaatca
    40741 tcccagctaa cgatgacgct atccgtgctg ttaaattgat cacagctaaa ttggctgacg
    40801 ctattatcga aggacgtcaa ggtgaggatg cagtagcagt tgaagcagaa tttgcagctt
    40861 cagaaactca agcagattca attgaagaaa tcgttgaagt tgtagaaggt gacaacgctt
    40921 aatttataca aatagtaatt acctaggagg gcggggctta gcccggctct cctattttca
    40981 aaaaatatag gagaattaaa atggcagaaa ttacagctaa acttgtaaaa gagttgcgtg
    41041 aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct tgtagaaaca gacggtgaca
    41101 tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc taaggcagct aagaaagctg
    41161 accgtgttgc tgcagaaggt ttgactggtg tttatgttaa cggtaatgtt gcagcagtta
    41221 ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc tcaattcgtt gaattggtaa
    41281 atactacagc taaagtcatt gctgaaggaa aacctgctaa taatgaagaa gctcttgctt
    41341 tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt atctgcaaca gcaactatcg
    41401 gagagaaaat ctcattccgt cgctttgcat tgattgaaaa aacagacgca caacactttg
    41461 gagcatacca acataacggt ggacgtatcg gtgttatttc agttgttgaa ggtggagacg
    41521 aagcacttgc taaacaattg tcaatgcaca tcgcagcgat gaaaccaaca gttctttctt
    41581 acaaagaatt ggatgagcaa ttcgttaaag atgagttggc acaattgaat cacgttatcg
    41641 accaagacaa cgaaagccgt gcaatggtta ataaaccagc tcttccacac ttgaagtatg
    41701 gatcaaaagc tcaattaact gatgatgtta ttgctcaagc tgaagctgac atcaaagctg
    41761 aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa aattatccca ggtaaaatgg
    41821 atcgcttcat gcttgataat actaaagttg accaagctta cacacttctt gcacaagttt
    41881 acatcatgga tgacagcaag acagttgaag cataccttga atcagttaac gcttcggtag
    41941 ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa agctgcaaac gacttcgaag
    42001 ctgaagttgc agctacaatg gcagcagcct tgaataacta ataatagaaa ggaagcaatt
    42061 tgcttccttt tttgtatagg gcttatattt ttcctgaaat tgtttttccc ccagtctcac
    42121 tcgattagaa taattaaaac aaaaagccct ataataaggg ctaagtgcat ttaggagact
    42181 atacttcaaa ttcatagtaa gcgcgtcata acaaggtatc tatcctaatt ccccaacttc
    42241 cagtatacta gataaaaaat aattatcgga ggaaaggtat tgtactatga tgattcaact
    42301 aagtgattta ggtcaagttc acattgtttg tggcaagaca gatatgaggc agggaataga
    42361 ctcattagcc tatgtagtta aaacccactt tgaattggat tctttctccg gtcaagtctt
    42421 tctcttttgt ggtggacgta aagaccgctt taaagtcctt tactgggatg gtcaaggatt
    42481 ttggctacta tataaacgct ttgagaacgg aaaactgact tggctaagta cagaaaagga
    42541 tgtcaaagct ctcgcacctg aacaagtaga ctagcttatg aagggctttt ctatcactcc
    42601 aaaaatatag tagattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    42661 tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta taaatccatc
    42721 agaaagtcgt gatttctatt gaaatgagga ctttcttttt acactcatct gctttcaaaa
    42781 agcattctag tccgtctccg attaacgatg gactttatca cctccttctc tagtccttgt
    42841 atgacatctt ccaaagttcg aaaggcttta ttcttaaatc cacgtttacg aatctctttc
    42901 cacacttgtt caatgggttc atctctggtg tgtatggagg aataaaggta aaaccaatat
    42961 tagtcggaat ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa
    43021 aataatcatc tggatgctcc tattcctaaa gcccctttag cgcatagctt tggctcagct
    43081 tctattatcg ctcacatcat ccatcagaag tttaatctga aggtacccaa ttatcgccaa
    43141 gaagaagatt gggctaggat gggtttacca atcacacgta aggaaatctc taatcggcat
    43201 atcaagacga gtcaatacta tttggagccc ctttataacc tcttgcgaga gagactattg
    43261 actcagccct tacttcatgc ggatgaaact tcttataggg tgctagagag tgatagtcag
    43321 ctgacttact attggacttt tttgtctggg aaagctgaga aacaagggat tacgctttac
    43381 catcatgtcc taatcgattt gttcatatct tatttcaatc cattataaat agtgagaaat
    43441 atctatccta tcttctagaa tgtcttccaa acgtggaaac tctcgtaaac aaagaggttt
    43501 tagaggccta tttaccatgg actaaagttg tacaagaaaa gtgcaaataa gaaatctcca
    43561 gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact tcgttattgg
    43621 acggttacaa ttcataaagt gctgtagaga gataacgttc accgttatct ggtgctaggg
    43681 caaggacttt tttacctgta cctaattttt tggcaacctc gatggctccg tagatagctg
    43741 cagctgagga aatccctaca aggaagcctt cttttccacc aatttcacgt ccgagtgcaa
    43801 gagcgtcatc tgatgttaca cgaacgatac catcataggc tttagtatca agtgtatcag
    43861 gaataaatcc agctgagata ccttgaattt tgtgaggacc aggtttttca ccagatagaa
    43921 tagcagattc atctgcttct actgcaaaaa cttgaatgtt agaattttct gatttgagtg
    43981 catgagaaac accagaaatc gttccaccag tacctactcc agcaacaaag gcatctaatc
    44041 catctttacc gaaagcagct agtatctcag ctcctgttgt tctttcgtgt acttctggat
    44101 tagctggatt gtcaaattga agaggaagga aaccatcacg ttcagcagcg atttcttgag
    44161 ccttagcaat agcacctttc attccctcgc taccaggagt taggacgagt tcagcaccat
    44221 aagcttggat aattttacgt cgttctacac tcatagtttc aggcataacg atgacgactt
    44281 tatacccttt agcagcacct acccatgaaa gtccaatacc ggtgtttcca cttgttgctt
    44341 caacaatagt agaaccaagt ttcagaatac catcttgttc agctttttca atcatgctaa
    44401 gggcaatacg gtcttttaca gatgaaccag gattaaatgc ttcaagcttt atatagacgt
    44461 ctgcagcacc ttctggcacg atgttgttaa gtttaacaat cggtgtttga ccgattaatt
    44521 cagtaatgtt gttataaata gacatatgaa tacctctttg tataagatat ctttagtata
    44581 acgctatcca taccatttgt aaaatataga aatcctatcg aagcgatagg atttctatat
    44641 atcatagatc aaagtcatta attttcaagt gattgcgttc agttaattct agtaaatagg
    44701 tgtgaaggaa aacgatatca ggtttcgttt gaattgcttc attttctagt atattttggt
    44761 acgcatcttt ttattttgct cgctaaagta gttgtgagaa tgtcaacgaa acgctgtatt
    44821 attcattgtt tacactaagt ttacaggaac ttcaacctct cgtaaacctt ggtcagttaa
    44881 agtgactttt ccattaaaaa actccacaag tgcagcttta atagtttctt tttcttcttt
    44941 atcaacataa atcatcgtat cgacttgatc tgtaaagttt gtatccagct ccatgagatc
    45001 atgttcttta aggaagttac tgtactcttg gtactgagca taagacattt gaatagcaat
    45061 gccagcctgt tcttttattt caataatacc aatttctttg acagctaagg cgacactgcc
    45121 ggcgtaagca cgaattagtc ctccagcgcc tagtttaata ccaccaaagt agcgtgtcac
    45181 gaccacacag acattggtga gattgtgatt ttctagtacc ccaagcatgg gaacaccagc
    45241 agtaccacta ggctcaccat catcacttgt acgtttaatt tcactacgtt ctccaataat
    45301 aaaggcagag cagttatgtg tcgctttgta gtgttctttt ttgatggcag taatgaagtc
    45361 acgagcctct tcttcgctat aaacacgctt ggcatggcag ataaagcgag attttttgat
    45421 ttcttcttgg acttggccgt cctctttaat tgtcctaaat tccatgattt aattgtacta
    45481 aaaaatcatc taaagtgcta gtttttacga ataaagaagt atgaaagtaa atttagatta
    45541 tctcggtcgt ttatttactg agaatgaatt aacagaagaa gaacgtcagt tggcggagaa
    45601 acttccagca atgagaaagg agaaggggaa acttttctgt caacgttgta atagtactat
    45661 tctagaagaa tggtatttgc ccatcggtgc ttactattgt cgagagtgct tgctgatgaa
    45721 gcgagtcaga agtgatcaaa ctttatacta ttttccgcag gaggattttc cgaagcaaga
    45781 tgttctcaaa tggcgcggcc aattaactcc ttttcaagag aaggtgtcag agggactgct
    45841 tcaagcagta gacaagcaaa agccaacctt agttcatgcg gtaacaggag ctggaaagac
    45901 agaaatgatt tatcaagtag tggctaaagt gatcaatgcg ggtggtgcag tgtgtttggc
    45961 tagtcctcgc atagatgttt gtttggagct gtacaagcgc ctgcaacagg atttttcttg
    46021 cggaatagct ttgctacatg gagaatcgga accttatttt cgaacaccac tagttgttgc
    46081 aacaacccat cagttattga agttttatca agcttttgat ttgctgatag tggatgaagt
    46141 agatgctttt ccttatgttg ataatcccat gctttaccac gctgtcaaga atagtgtaaa
    46201 ggagaatgga ttgagaatct ttttaacagc gacttcgacc aatgagttag ataaaaaggt
    46261 ccgtttagga gaactaaaaa gactgaattt accgagacgg tttcatggaa atccgttgat
    46321 tattccaaaa ccaatttggt tatcggattt taatcgctac ttagacaaga atcgtttgtc
    46381 accaaagtta aagtcctata ttgagaagca gagaaagaca gcttatccgt tactcatttt
    46441 tgcttcagaa attaagaaag gggagcagtt agcagaaatc ttacaggagc aatttccaaa
    46501 tgagaaaatt ggctttgtat cttctgtaac agaggatcga ttagagcaag tacaagcttt
    46561 tcgagatgga gaactgacaa tacttatcag tacgacaatc ttggagcgtg gagttacctt
    46621 cccttgtgtg gatgttttcg tagtagaggc caatcatcgt ttgtttacca agtctagttt
    46681 gattcagatt ggtggacgag ttggacgaag catggataga ccgacaggag atttgctttt
    46741 cttccatgat gggttaaatg cttcaatcaa gaaggcgatt aaggaaattc agatgatgaa
    46801 taaggaggct ggtctatgaa gtgcttgtta tgtgggcaga ctatgaagac tgttttaact
    46861 tttagtagtc tcttacttct gaggaatgat gactcttgtc tttgttcaga ctgtgattct
    46921 acttttgaaa gaattgggga agagaactgt ccaaattgta tgaaaacaga gttgtcaaca
    46981 aagtgtcaag attgtcaact ttggtgtaaa gaaggagttg gagtcagtca tagagcgatt
    47041 tttacttaca atcaagctat gaaggatttt ttcagtcggt ataagtttga tggagacttc
    47101 ctgttaagaa aagttttcgc ttcattttta agtgaggagt tgaaaaagta caaagagtat
    47161 caatttgttg taattcccct aagtcctgat agatatgcta atagaggatt taatcaggtt
    47221 gagggcttgg tagaggcagc aggctttgag tatctagatt tattagagaa aagagaagag
    47281 agagccagtt cttctaaaaa tcgttcagag cgcttgggga cagaacttcc tttctttatt
    47341 aaaagtggag tcactattcc taaaaaaatc ctacttatag atgatatcta tactacagga
    47401 gcaactataa atcgtgttaa gaaactgttg gaagaagccg gtgctaagga tgtaaaaaca
    47461 ttttcccttg taagatgagg aaaaaatttg caaaaataga atgaaagcgt tataataaaa
    47521 tcataaaaac aaaaatgttt agaaagaagg tactcatatg attaaatata gtatccgtgg
    47581 tgaaaaccta gaagtaacag aagcaattcg tgattatgta gtttctaaac tcgaaaagat
    47641 cgaaaagtac ttccaaccag aacaagagtt ggatgcccga attaacttaa aagtttatcg
    47701 tgaaaaaacg gctaaagtgg aagtaacgat tccgcttgga tctattactc tccgcgcaga
    47761 agatgtatct caagatatgt atggttcaat tgaccttgta actgataaaa ttgaacgtca
    47821 gattcgtaaa aataaaacaa aaatcgagcg taaaaataaa aataaggtag caactggtca
    47881 attatttaca gatgctttgg tggaagattc aaatattgtc cagtctaaag ttgttcgttc
    47941 aaaacaaatt gatttaaaac caatggattt ggaagaagca attctacaaa tggatttatt
    48001 ggggcatgat ttctttatct atgtggatgt tgaagatcag acaaccaatg tgatttatcg
    48061 tcgtgaggat ggcgaaattg gtttgttaga ggttaaagaa tcttaatttc aatatgtgta
    48121 aaggtaggtt tactgaattg taaactacct ttttcttata attgatagaa ttactgatta
    48181 cacttttaaa aagtcgcttt ttgaggggta ttatggtata atgggtgcca agaggttttg
    48241 aatgaaaaaa ttttatgtaa gtccaatttt tcctattcta gtaggattga ttgcgtttgg
    48301 agtcttatcc actttcatta tttttgttaa taataatctg ttgacggttt taattttgtt
    48361 tctttttgta ggaggctatg tttttttatt taagaaactg agagtgcatt atacaaggag
    48421 tgatgtagaa cagatacagt atgtaaacca ccaagcggaa gaaagtttga cagctctatt
    48481 ggaacagatg cctgtaggtg ttatgaaatt gaatttatct tctggagagg ttgagtggtt
    48541 taatccctat gctgaattga ttttgaccaa ggaagatggt gattttgatt tagaagctgt
    48601 tcaaacgatt atcaaggctt cagtaggaaa tccgtctact tatgccaagc ttggtgagaa
    48661 gcgttatgct gttcatatgg atgcttcttc cggtgttttg tattttgtag atgtatccag
    48721 ggaacaagcc ataacagatg aattggtaac aagtcgacca gtgattggga ttgtctctgt
    48781 ggataattat gatgatttgg aggatgcaac ttctgagtca gatattagtc aaatcaatag
    48841 ttttgtagct aattttatat cagagttttc agaaaaatac atgatgtttt ctcgtcgggt
    48901 aagtatggat cgattttatc tatttactga ctacacggtg cttgagggct tgatgaatga
    48961 taaattttct gttattgatg ctttcagaga agagtcgaaa cagagacagt tgcccttgac
    49021 tttaagtatg ggattttctt atggcgatgg aaatcatgat gagataggga aagttgcttt
    49081 gctcaatttg aacttggctg aagtacgtgg tggcgaccag gtggttgtta aggaaaacga
    49141 cgaaacgaaa aatccagttt attttggtgg tgggtctgct gcttcaatca agcgtacacg
    49201 gactcgtacg cgcgctatga tgacagctat ttcagataag attcggagtg tagatcaggt
    49261 ttttgtagtc ggtcacaaaa atttagacat ggatgctttg ggctctgctg taggtatgca
    49321 gttgttcgcc agcaatgtga ttgaaaatag ctatgctctt tatgatgaag aacaaatgtc
    49381 tccagatatt gaacgagctg tttcattcat agaaaaagaa ggagttacga agttgttgtc
    49441 tgttaaggat gcaatgggga tggtgaccaa tcgttctttg ttgattcttg tagaccattc
    49501 aaagacagcc ttaacattat caaaagaatt ttatgattta tttacccaaa ccattgttat
    49561 tgaccaccat agaagggatc aggattttcc agataatgca gtcattactt atatcgaaag
    49621 tggtgcaagt agtgccagtg agttggtaac ggaattgatt cagttccaga attctaagaa
    49681 aaatcgtttg agtcgtatgc aagcaagtgt tttgatggct ggtatgatgt tggatactaa
    49741 aaatttcacc tcgcgagtaa ctagtcggac atttgatgtt gctagctatc tcagaacgcg
    49801 cggaagtgat agtattgcta tccaggaaat tgctgcgaca gattttgaag aatatcgtga
    49861 ggttaatgaa cttattttac aggggtgtaa attaggttca gatgtactaa tagcagaggc
    49921 taaggacacg aaatgctatg atacagttgt tattagtaag gcagcagatg ccatgttagc
    49981 catgtcaggt attgaagcga gttttgttct tgcgaagaat acacaaggat ttatctctat
    50041 ctcagctcga agtcgtagta aactgaatgt acaacggatt atggaagagt taggcggtgg
    50101 aggccacttt aatttggcag cagctcaaat taaagatgta accttgtcag aagcaggtga
    50161 aaaactgaca gaaattgtat taaatgaaat aaaggaaaag gagaaagaag aatgaaagta
    50221 atctttttag cagatgttaa aggaaaaggt aaaaaaggcg aaattaagga agtaccaaca
    50281 gggtatgcgc aaaactttct tatcaaaaag aatctagcca aagaagcgac tgctcaagct
    50341 gtaggtgaac ttcgtggtaa acaaaaatcg gaagaaaaag ctcacgctga gatgattgca
    50401 gaaggaaaag caattaaagc acaacttgaa gcagaagaaa ctgttgtaga atttgttgaa
    50461 aaagttggtc cagatggtcg tacctttggt tctattacca ataagaagat tgcagaagaa
    50521 ttgcaaaagc aatttggaat taagattgat aaacgtcata ttcaagtaca agctccgatt
    50581 cgagcggttg gtttgattga tgtgccagtg aaaatctatc aagatatcac aagtgtaatc
    50641 aatcttcgtg tgaaagaagg ataagtttac accttcttga caagattgta aaaggaaggg
    50701 aagtctgatg gcagaagtag aagagttacg agtacaacct caagatatct tagctgagca
    50761 atccgtttta ggggctatct ttattgatga gagtaaactt gtttttgtgc gagaatacat
    50821 tgagtctcgg gactttttta agtatgccca tcgtttgatt ttccaagcca tggtcgattt
    50881 atccgatcgt ggtgatgcca tagatgcaac aacggttcgt actatccttg ataatcaagg
    50941 tgatttacag aatattggtg gcttgtctta cttggttgag attgttaatt ctgtgccaac
    51001 ttctgctaat gcggagtatt atgctaagat tgttgcagaa aaagcaatgc tacgtcgttt
    51061 aattgccaag ttgacagagt ctgtcaacca agcttacgaa gcgtcacaac cagctgatga
    51121 aattattgct caggcagaaa aagggttgat tgatgtcagt gaaaatgcaa atcgaagcgg
    51181 gtttaagaac attcgagatg tgttgaatct caactttgga aatctggaag ctcgctcgca
    51241 acaaacgacc gatattacag gtattgcgac aggttatcgt gatttggatc atatgacaac
    51301 aggacttcat gaggaggagt tgattatctt agcagctcgt ccagcagttg gtaagacagc
    51361 atttgccttg aatatcgctc agaatattgg gactaagttg gacaaaacgg ttgctatttt
    51421 ttcactcgaa atgggtgcgg aaagcttggt agaccgtatg ttagctgcag aaggcttggt
    51481 ggagtcacat tctatccgta cagggcaatt gacagatgag gagtggcaaa aatatactat
    51541 tgctcagggt aatctagcta acgccagtat ctatatcgat gatacgccag gtattcggat
    51601 tacagagatt cgttctcgtt ctcgtaaatt ggctcaagaa actggaaatc ttggtttgat
    51661 tttgatagac tatttgcaac ttatcacggg aactggtcga gaaaatcgtc aacaagaagt
    51721 ttctgaaatt tctcgtcagt tgaaaatact agccaaggaa ttgaaggttc cagtaatcgc
    51781 tctgagtcag ctttctcgtg gtgtagaaca acgtcaggac aagagaccgg tcttgtctga
    51841 tattcgtgaa tctgggtcta ttgagcagga cgctgatatc gtagcttttc tctatcgcga
    51901 tgactactat gaacgtggtg gtgaagaaga ggagggtatc ccaaataata aggtggaagt
    51961 tattatcgag aaaaaccgta gtggagctcg tggaacagtg gaattgattt tccaaaaaga
    52021 atacaataaa ttttcaagta tctcaaagag ggaggcataa gatgtcagat gcatttacag
    52081 atgtagccaa gatgaaaaaa atcaaagaag aaatcaaggc acatgaggga caagtcgtag
    52141 aaatgacttt ggagaatggt cgtaagcgcc aaaaaaatag attgggtaag ctaattgaag
    52201 tttatccatc cctatttatt gtggagtttg gggatgtgga aggagataaa caagttaatg
    52261 tttacgttga atcctttact tactcagata ttcttacaga aaagaatttg attcattatc
    52321 ttgactaaag tgagaaattt tctcactttt tcttttttct ccgaataatt taggtgaagg
    52381 caatcatcgc tttatattat tttttaagga ggaagaatga aaattttacc gtttatagca
    52441 agaggaacaa gttattactt gaagatgtca gttaaaaagc ttgttccttt tttagtagta
    52501 ggattgatgc tagcagctgg tgatagtgtc tatgcctatt ccagaggaaa tggatcgatt
    52561 gcgcgtgggg atgattatcc tgcttattat aaaaatggga gccaggagat tgatcagtgg
    52621 cgcatgtatt ctcgtcagtg tacttctttt gtagcctttc gtttgagtaa tgtcaatggt
    52681 tttgaaattc cggcagctta tggaaatgcg aatgaatggg gacatcgtgc tcgtcgggaa
    52741 ggttatcgtg tagataatac accgacgatt ggttccatta cttggtctac tgcaggaact
    52801 tatggtcatg ttgcctgggt gtcaaatgta atgggagatc agattgagat tgaggaatat
    52861 aactatggtt atacagaatc ctataataaa cgagttataa aagcaaacac gatgacagga
    52921 tttattcatt ttaaagattt ggatagtggc agtgttggga atagtcaatc ctcagcttca
    52981 acaggcggaa ctcattattt taagaccaag tctgctatta aaactgaacc cctagttagt
    53041 gcaactgtga ttgattacta ttatcctggg gagaaggttc attatgatca gatacttgaa
    53101 aaagacggct ataagtggtt gagttatact gcctataatg gaagctatcg ttatgttcaa
    53161 ttggaggctg tgaataaaaa tcctctaggt aattctgttc tttcttcaac aggaggaact
    53221 cattatttta agatcaagtc tgctattaaa actgaacccc tagttagtgc aactgtgatt
    53281 gattactatt atcctggaga gaaggttcat tatgatcaga tacttgaaaa agacggctat
    53341 aagtggttga gttatacggc ttataacgga agtcgtcgct atatacagct agagggagtg
    53401 acttcttcac aaaattatca gaatcaatca ggaaatatct ctagctatgg atccaataat
    53461 agttcaactg tcggttggaa gaaaataaat ggtagttggt atcatttcaa atcaaatggt
    53521 tctaaatcaa caggatggct gaaagacggt tctagctggt attatttgaa attatctggt
    53581 gaaatgcaga caggatggtt aaaggagaat ggctcgtggt attatctggg tagttcaggg
    53641 gcaatgaaaa caggctggta ccaggtctct ggtaagtggt attattctta ctcttcaggc
    53701 gccttagcta ttaatacgac ggtggatggc tacagagtaa acagtgatgg agaacgagta
    53761 tagaaaattg gagtaggaga aatttcctgc tcttttctgt aagcagtttc cttgacattt
    53821 ttcttatttt gcgctatcat atatacatat aatatatggg agtctgtgta cagtctgaga
    53881 ggaagtgtta aacttcgacc gcacctgatc tgggtaatgc cagcggaggg aacgatactt
    53941 agtctaattt tgcacctttt ccatgtatgg taaaggtttt tctttttttt aaaaggaaaa
    54001 cgagaagagg aggttcttat gaaagcaagc attgccttgc aagttttacc cctagcacag
    54061 gggattgatc ggatagctgt tattgatcag gtcattgctt atctgcaaac tcaagaagtg
    54121 acgatggtag tgacaccatt tgaaacggtc ttggaagggg agtttgatga gcttatgcgc
    54181 attctaaaag aagcgctgga agtggcagtg caggaggcag acaatgtctt tgccaatgtc
    54241 aaaataaatg taggagagat tttaagtatt gatgagaaac ttgaaaagta tactgagacg
    54301 acacattagt ctattgggct ttctcggagt attgtcaatc tggcagttag caggttttct
    54361 taaacttctc cccaagttta tcctgccgac acctcttgaa attctccagc cctttgttcg
    54421 tgacagagaa tttctctggc accatagctg ggcgaccttg agagtggctt tactggggct
    54481 gattttggga gttttgattg cctgtcttat ggctgtgctc atggatagtt tgacttggct
    54541 caatgacctg atttacccta tgatggtggt cattcagacc attccgacca ttgccatagc
    54601 tcctatcctg gtcttgtggc tgggttatgg gattttgccc aagattgtct tgattatctt
    54661 aacaacaacc tttcccatca tcgttagtat tttggacggt tttaggcatt gtgacaagga
    54721 tatgctgact ttgtttagtc tgatgcgagc aaacccttgg caaatcctgt ggcattttaa
    54781 aatcccggtt agcctgcctt acttttatgc aggtctgagg gtcagtgtct cctacgcctt
    54841 tatcacaact gtggtatctg agtggttggg aggttttgaa ggtcttggtg tttatatgat
    54901 tcagtctaaa aaactgtttc agtatgatac catgtttgcc attattattc tggtgtcgat
    54961 tatcagtctt ttgggtatga agctggtcga tatcagtgaa aaatatgtga ttaaatggaa
    55021 acgtacttaa aatagagcgt ttttgaaaaa gaaaagagga aatcaaaatg aagaaaacat
    55081 ggaaagtgtt tttaacgctt gtaacagctc ttgtagctgt tgtgcttgtg gcctgtggtc
    55141 aaggaactgc ttctaaagac aacaaagagg cagaacttaa gaaggttgac tttatcctag
    55201 actggacacc aaataccaac cacacagggc tttatgttgc caaggaaaaa ggttatttca
    55261 aagaagctgg agtggatgtt gatttgaaat tgccaccaga agaaagttct tctgacttgg
    55321 ttatcaacgg aaaggcacca tttgcagtgt atttccaaga ctacatggct aagaaattgg
    55381 aaaaaggagc aggaatcact gccgttgcag ctattgttga acacaataca tcaggaatca
    55441 tctctcgtaa atctgataat gtaagcagtc caaaagactt ggttggtaag aaatatggga
    55501 catggaatga cccaactgaa cttgctatgt tgaaaacctt ggtagaatct caaggtggag
    55561 actttgagaa ggttgaaaaa gtaccaaata acgactcaaa ctcaatcaca ccgattgcca
    55621 atggcgtctt tgatactgct tggatttact acggttggga tggtatcctt gctaaatctc
    55681 aaggtgtaga tgctaacttc atgtacttga aagactatgt caaggagttt gactactatt
    55741 caccagttat catcgcaaac aacgactatc tgaaagataa caaagaagaa gctcgcaaag
    55801 tcatccaagc catcaaaaaa ggctaccaat atgccatgga acatccagaa gaagctgcag
    55861 atattctcat caagaatgca cctgaactca aggaaaaacg tgactttgtc atcgaatctc
    55921 aaaaatactt gtcaaaagaa tacgcaagcg acaaggaaaa atggggtcaa tttgacgcag
    55981 ctcgctggaa tgctttctat aaatgggata aagaaaatgg tatccttaaa gaagacttga
    56041 cagacaaagg cttcaccaac gaatttgtga aataatgaca gaaattagac tagagcacgt
    56101 cagttatgcc tatggtcagg agaggatttt agaggatatc aacctacagg tgacttcagg
    56161 cgaagtggtt tccatcctag gcccaagtgg tgttggaaag accaccctct ttaatctaat
    56221 cgctgggatt ttagaagttc agtcagggag aattgtcctt gatggtgaag aaaatcccaa
    56281 ggggcgcgtg agttatatgt tgcaaaagga tctgctcttg gagcacaaga cggtgcttgg
    56341 aaatatcatt ctgcccctct tgattcaaaa ggtggataag gcagaagcta tttcccgagc
    56401 ggataaaatt cttgcgacct tccagctgac agctgtaaga gacaagtatc ctcatgaact
    56461 tagcggtggg atgcgccagc gtgtagcctt actccggacc tacctttttg ggcacaagct
    56521 ctttctctta gatgaggcct ttagcgcctt ggatgagatg acaaagatgg aactccacgc
    56581 ttggtatctt gagattcaca agcagttgca gctaacaacc ctgatcatca cgcatagtat
    56641 tgaggaggcc ctcaatctca gcgaccgcat ctatatcttg aaaaatcgcc ctgggcagat
    56701 tgtttcagaa attaaactag attggtctga agatgaggac aaggaagtcc aaaagattgc
    56761 ctacaaacgt caaatcttgg cagaattagg cttagataag tagaaaaata gggagttggt
    56821 gaagattatc ctttaccagc gccctttttc ttttaaaaat gagaaaattt cggtataata
    56881 gtcaaacaag gtcaaggttt aaagagagag gtgggtttgt tatgagattt aaaaatacat
    56941 cggatcatat tgaggcctac atcaaggcga ttttagatca atctggtatc gtggagttgc
    57001 aacggagtca gttggcagat acctttcagg ttgttcctag tcagattaac tacgtgatca
    57061 agacacgctt tacggaaagt agaggctact tggttgaaag taagcgtggt ggtggaggct
    57121 acattcgtat aggacgaatt gagttttcta gtcatcatga aatgctccgg gagctgcttt
    57181 actcgattgg tgagcgagtc agtcaagaaa tttatgagga tattctccag cttttggttg
    57241 agcaggaatt gatgaccaag caggagatga atttgctaga atcagtagct ttggatcgcg
    57301 ttttaggaga agaagctcca gttgttcgag caaacatgct acgtcagatc atacaagagg
    57361 tagatagaaa agggaagtaa gatgaactat tcaaaagcat tgaatgaatg tatcgaaagt
    57421 gcctacatgg ttgctggaca ttttggagct cgttatctag agtcttggca cttgttgatt
    57481 gccatgtcta atcacagtta tagtgtagca ggggcaactt taaatgatta tccgtatgag
    57541 ctggaccgtt tagaagaggt ggctttggaa ctgactgaaa cggactatag ccaggatgaa
    57601 acttttacgg aattgccgtt ctcccgtcgt ttgcagattc tttttgacga agcagagtat
    57661 gtagcgtcag tggtccatgc taaggtgcta gggacagagc acgtcctcta tgcgattttg
    57721 catgatggca atgccttggc gactcgtatc ttggagaggg ctggtttttc ttatgaagac
    57781 aagaaagatc aggtcaagat tgctgctctt cgtcgaaatt tagaagaacg ggcaggctgg
    57841 actcgtgaag atctcaaggc tttacgccaa cgccatcgta cagtagctga caagcaaaat
    57901 tctatggcca atatgatggg catgccgcag actcctagtg gtggtctcga ggactatacg
    57961 catgatttga cagagcaagc gtgttctggc aagttagaac cagtcatcgg tcgggacaag
    58021 gaaatctcac gtatgattca aatcttgagc cggaagacta agaacaaccc tgtcttggtt
    58081 ggggatgctg gtgtcgggaa aacagctctg gcgcttggtc ttgctcagcg tattgctagt
    58141 ggtgacgtgc ctgcggaaat ggctaagatg cgcgtgttag aacttgattt gatgaatgtc
    58201 gttgcaggga cacgcttccg tggtgacttt gaagaacgca tgaataatat catcaaggat
    58261 attgaagaag atggccaagt catcctcttt atcgatgaac tccacaccat catgggttct
    58321 ggtagcggga ttgattcgac tctggatgcg gccaatatct tgaaaccagc cttggcgcgt
    58381 ggaactttga gaacggttgg tgccaccact caggaagaat atcaaaaaca tatcgaaaaa
    58441 gatgcggctc tttctcgtcg tttcgctaaa gtgacgattg aagaaccaag tgtggcagat
    58501 agtatgacta ttttacaagg tttgaaggcg acttatgaga aacatcaccg tgtacaaatc
    58561 acagatgaag cggttgaaac agcggttaag atggctcatc gttatttaac cagtcgtcac
    58621 ttgccagact ctgctatcga cctcttggac gaagcagcag caacagtgca aaataaggta
    58681 aagtatgtaa aagcagacga ttcagatttg agtccagctg ataaggccct gatggatggc
    58741 aagtggaaac aggcagccca gctaatcgca aaagaagagg aagtacctgt ctacaaagac
    58801 ttggtgacag agtctgatat tttgaccacc ttgagtcgct tgtcaggaat cccagttcaa
    58861 aaactgactc aaacggatgc taagaagtat ctaaatcttg aagcagaact ccataaacgt
    58921 gtcatcggtc aagatcaagc tgtttcaagc attagtcgtg cgattcgccg taatcagtca
    58981 ggaattcgca gtcacaagcg tccgatcggt tcctttatgt tcctaggacc cacaggtgtc
    59041 ggtaagaccg agttggccaa ggctttggca gaagttctct ttgatgacga atcagccctt
    59101 atccgctttg atatgagtga gtatatggag aaattcgcag ccagccgtct aaatggagct
    59161 cctccaggct atgtgggtta cgaagaaggt ggagagttga cagagaaggt tcgcaataaa
    59221 ccctattccg ttctcctctt tgatgaggta gagaaggccc acccagatat ctttaatgtt
    59281 ctcttgcaag ttctggatga cggtgttttg acagatagca agggacgcaa ggtcgatttt
    59341 tcaaatacca ttatcattat gacatcgaac ctaggtgcga ctgcccttcg tgatgataag
    59401 actgttggtt ttggggctaa ggatattcgt tttgaccagg aaaatatgga aaaacgcatg
    59461 tttgaagaac tgaaaaaagc ttatagaccg gaattcatca accgtattga tgagaaggtg
    59521 gtcttccata gcctatctag tgaccatatg caggaagtgg tgaagattat ggtcaagcct
    59581 ttagtggcaa gtttggctga aaaaggcatt gacttgaaat tacaagcttc agctctgaaa
    59641 ttgttagcaa atcaaggata tgacccagag atgggagctc gcccacttcg cagaaccctg
    59701 caaacagaag tggaggacaa gttggcagaa cttcttctta agggagattt agtggcaggc
    59761 agcacactta agattggtgt caaagcaggc cagttaaaat ttgatattgc ataaaagaat
    59821 aaaagtatca gcatctgacc ataagtcaca gtggagtgaa actcaatgaa aatcaaagag
    59881 caaactaggc agctagccgc aggttgctca aaacactggt ttgaggttgc agatagagct
    59941 gacgtggttt gaagagattt tcgaagagta tgaaactaaa acctatagct tctaaacgat
    60001 ccgtggtttt caccattcaa cacaaaattc atatgtttat taccctccgt cgtatttgtc
    60061 ttagagcgtg tgtagtagaa aaagagcagt cttatctgaa atttttattc tttcaaaaga
    60121 gacctgtttc ttttttgcat gtcaaatccg ttctagctgg tatttgaaaa atcaaactaa
    60181 tattcaatga aaatcaaaga acaaactagg cagctagcca caggttgctc aaaacactgt
    60241 ttttagattg tagatagagc tgacgtggtt tgaagagatt ttcgaagagt ataagctgca
    60301 agatgaatga ttttcttgta ttgacgttgt tgttgacaaa aagtagcgga taaatgaaat
    60361 ccattccatt atcatagatg ataggctggt aggaaatttt caaatagcat acaggaaata
    60421 gatgtatgga gttctggtag tagaaaggga gagagatgaa cattttagtt gcagatgacg
    60481 aggaaatgat tagagaagga attgcagcat ttctgacaga agagggttat catgtcatta
    60541 tggctaagga tggacaagag gtcttggaaa aatttcaaga tctccctatc catctcatgg
    60601 tactggattt aatgatgcct aggaagagtg gttttgaagt gttaaaagaa atcaatcaaa
    60661 agcacgatat tcctgtcatc gtcttgagtg ctctgggaga tgaaactact cagtcacagg
    60721 tatttgatct ctatgctgat gatcatgtga caaaaccttt ttctttggta ctgcttgtca
    60781 agcgtattaa ggcgcttatc agacgttact acgtcataga ggatatttgg cgatatcagg
    60841 atgtaacagt ggattttacc tcttacaaag cacattataa aaatgaagaa attgatctca
    60901 aaccaaagga attactggta ctaaagtgtt tgattcagca taaaaatcaa gttttaagta
    60961 gagagcagat attggaagaa atttcaaaag atgtagctga tttaccttgt gatagggtcg
    61021 ttgatgtcta tattcgtact cttcgcaaaa aattagcttt agattgtatc gtgactgtga
    61081 aaaatgttgg gtataagatt agcttatgat aaaaaatcct aaattattaa ccaagtcttt
    61141 tttaagaagt tttgcaattc taggtggtgt tggtctagtc attcatatag ctatttattt
    61201 gacctttcct ttttattata ttcaactgga gggggaaaag tttaatgaga gcgcaagagt
    61261 gtttacggag tatttaaaga ctaagacatc tgatgaaatt ccaagcttac tccagtctta
    61321 ttcaaagtcc ttgaccatat ctgctcacct taaaagagat attgtagata agcggctccc
    61381 tcttgtgcat gacttggata ttaaagatgg aaagctatca aattatatcg tgatgttaga
    61441 tatgtctgtt agtacagcag atggtaaaca ggtaacagtg caatttgttc acggggtgga
    61501 tatctacaaa gaagcaaaga atattttgct tttgtatctc ccatatacat ttttggttac
    61561 aattgctttt tcctttgttt tttcttattt ttatactaaa cgcttgctca atcctctttt
    61621 ttacatttca gaagtgacta gtaaaatgca agatttggat gacaatattc gttttgatga
    61681 aagtaggaaa gatgaagttg gtgaagttgg aaaacagatt aatggtatgt atgagcactt
    61741 gttgaaggtt attcatgagt tggaaagtcg taatgagcaa attgtaaaat tgcaaaatca
    61801 aaaggtttcc tttgtccgtg gagcatcaca tgagttgaaa acccctttag ccagtcttag
    61861 aattatccta gagaatatgc agcataatat tggagattac aaagatcatc caaaatatat
    61921 tgcaaagagt ataaataaga ttgaccagat gagccactta ttagaagaag tactggagtc
    61981 ttctaaattc caagagtgga cagagtgtcg tgagaccttg actgttaagc cagttttagt
    62041 agatatttta tcacgttatc aagaattagc tcattcaata ggtgttacaa ttgaaaatca
    62101 attgacagat gctaccaggg tcgtcatgag tcttagggca ttggataagg ttttgacaaa
    62161 cttgattagt aatgcaatta aatattcaga taaaaatggg cgcgtaatca tatccgagca
    62221 agatggctat ctctctatca aaaatacatg tgcgcctcta agtgaccaag aactagaaca
    62281 tttatttgat atattctatc attctcaaat cgtgacagat aaggatgaaa gttccggttt
    62341 gggtctttac attgtgaata atattttaga aagctatcaa atggactata gttttctccc
    62401 ttatgaacac ggtatggaat ttaagattag cttgtagaca gattagtttt ttattaaagt
    62461 tcatataggg ttaacataag tgtgttattc tttgcataga taaaagaaag gatactaata
    62521 tggtattagc gattatttta gtaacattct ttattcgatt gattttttta aagcgttcga
    62581 tagagaatga gaaacgaatc cttagcaatg gcgggaaaga atttggagtt gagaatacaa
    62641 aacgattaac tatggctcat attgtttttt atctctcttg cttggttgag gcagtggtgc
    62701 acaagacaat ttttgatggc atgggtatgg ttggtttggt cttgcttatt ttttctatgc
    62761 tgatgttgat gttggtgatt cacttgttgg gagatatttg gacagtgaag cttatgcttg
    62821 tcaataatca caaatatgta gatcatatct tgtttaggac agtaaaacat cctaattact
    62881 ttttaaatat tcttcctgag ttgattggct tgaccttgtt gagtcatgct tatgtgactt
    62941 ttgttttagt ttttccagtt tatgcagtta ttttgtatcg acgaatagct gaagaggaaa
    63001 agctattaca tgaagttata atcccaaatg gaagcataaa gagataaata caaaattcga
    63061 tttatataca gttcatattg aagtgatata gtaaggttaa agaaaaaata tagaaggaaa
    63121 taaacatgtt tgcatcaaaa agcgaaagaa aagtacatta ttcaattcgt aaatttagta
    63181 ttggagtagc tagtgtagta gttgccagtc ttgttatggg gagtgtggtt catgcgacag
    63241 agaacgaggg aagtacccaa gcagccactt tttctaatat ggcaaataaa agtcagacag
    63301 aacaaggaga aatcaatata gaacgagata aggcaaagac agcggtcagt gaatataaag
    63361 aaaaaaaagt gagtgagatc tatacaaaat tagagagaga tagacataaa gatactgtag
    63421 atctagttaa caagttgcaa gagattaaga acgagtattt gaataaaata gttcaatcaa
    63481 cctcaaaaac cgaaatacag ggacttatta caacaagtcg atcaaaacta gatgaagctg
    63541 tgtctaaata taaaaaggcc ccatcttctt cgtcaagttc aggctcttcc actaaaccgg
    63601 aagcttcaga tacagcgaag ccaaacaagc cgacagaact agaaaaaaag gtagcagaag
    63661 ctgagaagaa ggttgaagaa gctaagaaga aagccaagga tcaaaaagaa gaagattacc
    63721 gtaactaccc aaccattact tacaaaacgc ttgaacttga aattgctgag tccgatgtgg
    63781 aagttaaaaa agcggagctt gaactagtaa aagaggaagc taaggaacct cgaaacgagg
    63841 aaaaagttaa gcaagcaaaa gcgaaagttg agagtgaaga aactgaggct acaaggttag
    63901 aaaaaatcaa gacagatcgt aaaaaagcag aagaagaagc taaacgaaaa gcagcagaag
    63961 aagataaagt taaagaaaaa ccagctgaac aaccaaaacc agcgccggct cctcaaccag
    64021 aaaaaccagc tccaaaacca gagaatccag ctccaaaacc agagaatcca gctccaaaac
    64081 cagaaaaacc agctgaacaa caagctgaag aagactatgc tcgtagatca gaagaagaat
    64141 ataatcgctt gactcaacag caaccgccaa aaactgaaaa accagcacaa ccatctactc
    64201 caaaaacagg ctggaaacaa gaaaacggta tgtggtactt ctacaatact gatggttcaa
    64261 tggcgacagg atggctccaa aacaatggct catggtacta cctcaacagc aatggcgcta
    64321 tggcgacagg atggctccaa aacaatggtt catggtacta tctaaacgct aatggttcaa
    64381 tggcaacagg atggctccaa aacaatggtt catggtacta cctaaacgct aatggttcaa
    64441 tggcgacagg atggctccaa tacaatgg
//
LOCUS       DAVBOH010000007        60622 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOH010000007 DAVBOH010000000
VERSION     DAVBOH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.007"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            129..410
                     /locus_tag="VQ873_000424"
                     /pseudo
     CDS             129..410
                     /locus_tag="VQ873_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(535..738)
                     /locus_tag="VQ873_000425"
     CDS             complement(535..738)
                     /locus_tag="VQ873_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106752.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(731..1813)
                     /locus_tag="VQ873_000426"
     CDS             complement(731..1813)
                     /locus_tag="VQ873_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3106753.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1939..2721)
                     /locus_tag="VQ873_000427"
     CDS             complement(1939..2721)
                     /locus_tag="VQ873_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3106754.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2721..4064)
                     /locus_tag="VQ873_000428"
     CDS             complement(2721..4064)
                     /locus_tag="VQ873_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3106755.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4163..5479)
                     /locus_tag="VQ873_000429"
     CDS             complement(4163..5479)
                     /locus_tag="VQ873_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3106756.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5673..6899
                     /locus_tag="VQ873_000430"
     CDS             5673..6899
                     /locus_tag="VQ873_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3106757.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7098..8672
                     /locus_tag="VQ873_000431"
     CDS             7098..8672
                     /locus_tag="VQ873_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3106758.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8937..9725
                     /gene="codY"
                     /locus_tag="VQ873_000432"
     CDS             8937..9725
                     /gene="codY"
                     /locus_tag="VQ873_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3106759.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9725..10300
                     /locus_tag="VQ873_000433"
     CDS             9725..10300
                     /locus_tag="VQ873_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3106760.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10382..10467
                     /locus_tag="VQ873_000434"
     tRNA            10382..10467
                     /locus_tag="VQ873_000434"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10416..10418,aa:Leu,seq:aag)
     gene            10750..11880
                     /gene="ugpC"
                     /locus_tag="VQ873_000435"
     CDS             10750..11880
                     /gene="ugpC"
                     /locus_tag="VQ873_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3106761.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12381..13139
                     /locus_tag="VQ873_000436"
     CDS             12381..13139
                     /locus_tag="VQ873_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3106762.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13226..13738
                     /locus_tag="VQ873_000437"
     CDS             13226..13738
                     /locus_tag="VQ873_000437"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3106763.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13920..14864
                     /locus_tag="VQ873_000438"
     CDS             13920..14864
                     /locus_tag="VQ873_000438"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3106764.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14873..15550
                     /locus_tag="VQ873_000439"
     CDS             14873..15550
                     /locus_tag="VQ873_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3106765.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15648..16406
                     /locus_tag="VQ873_000440"
     CDS             15648..16406
                     /locus_tag="VQ873_000440"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3106766.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16444..17949
                     /gene="lytC"
                     /locus_tag="VQ873_000441"
     CDS             16444..17949
                     /gene="lytC"
                     /locus_tag="VQ873_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3106767.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18446..18964
                     /locus_tag="VQ873_000442"
     CDS             18446..18964
                     /locus_tag="VQ873_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3106768.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19094..19600
                     /locus_tag="VQ873_000443"
     CDS             19094..19600
                     /locus_tag="VQ873_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3106769.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19802..21034
                     /gene="clpX"
                     /locus_tag="VQ873_000444"
     CDS             19802..21034
                     /gene="clpX"
                     /locus_tag="VQ873_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3106770.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21043..21630
                     /locus_tag="VQ873_000445"
     CDS             21043..21630
                     /locus_tag="VQ873_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3106771.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21641..22021
                     /locus_tag="VQ873_000446"
     CDS             21641..22021
                     /locus_tag="VQ873_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3106772.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22073..22963
                     /gene="rapZ"
                     /locus_tag="VQ873_000447"
     CDS             22073..22963
                     /gene="rapZ"
                     /locus_tag="VQ873_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3106773.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22960..23937
                     /locus_tag="VQ873_000448"
     CDS             22960..23937
                     /locus_tag="VQ873_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3106774.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23934..24845
                     /gene="whiA"
                     /locus_tag="VQ873_000449"
     CDS             23934..24845
                     /gene="whiA"
                     /locus_tag="VQ873_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3106775.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24879..25847)
                     /locus_tag="VQ873_000450"
     CDS             complement(24879..25847)
                     /locus_tag="VQ873_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3106776.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25983..26840
                     /locus_tag="VQ873_000451"
     CDS             25983..26840
                     /locus_tag="VQ873_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3106777.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26827..27606
                     /locus_tag="VQ873_000452"
     CDS             26827..27606
                     /locus_tag="VQ873_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3106778.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27630..28982
                     /locus_tag="VQ873_000453"
     CDS             27630..28982
                     /locus_tag="VQ873_000453"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3106779.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29056..29430
                     /locus_tag="VQ873_000454"
     CDS             29056..29430
                     /locus_tag="VQ873_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3106780.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29432..30280
                     /locus_tag="VQ873_000455"
     CDS             29432..30280
                     /locus_tag="VQ873_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3106781.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30557..31324
                     /locus_tag="VQ873_000456"
     CDS             30557..31324
                     /locus_tag="VQ873_000456"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3106782.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31336..32520
                     /locus_tag="VQ873_000457"
     CDS             31336..32520
                     /locus_tag="VQ873_000457"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3106783.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32517..34388
                     /locus_tag="VQ873_000458"
     CDS             32517..34388
                     /locus_tag="VQ873_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3106784.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34531..35715)
                     /gene="mntE"
                     /locus_tag="VQ873_000459"
     CDS             complement(34531..35715)
                     /gene="mntE"
                     /locus_tag="VQ873_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3106785.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36019..38715
                     /locus_tag="VQ873_000460"
     CDS             36019..38715
                     /locus_tag="VQ873_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3106786.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38728..39519
                     /gene="yghU"
                     /locus_tag="VQ873_000461"
     CDS             38728..39519
                     /gene="yghU"
                     /locus_tag="VQ873_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3106787.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39635..40045
                     /locus_tag="VQ873_000462"
     CDS             39635..40045
                     /locus_tag="VQ873_000462"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3106788.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40057..41652
                     /locus_tag="VQ873_000463"
     CDS             40057..41652
                     /locus_tag="VQ873_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106789.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41719..41883
                     /locus_tag="VQ873_000464"
     CDS             41719..41883
                     /locus_tag="VQ873_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3106790.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41962..42690
                     /gene="yaaA"
                     /locus_tag="VQ873_000465"
     CDS             41962..42690
                     /gene="yaaA"
                     /locus_tag="VQ873_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3106791.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42967..43515)
                     /locus_tag="VQ873_000466"
     CDS             complement(42967..43515)
                     /locus_tag="VQ873_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3106792.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43836..44324
                     /locus_tag="VQ873_000467"
     CDS             43836..44324
                     /locus_tag="VQ873_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3106793.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44321..45508
                     /locus_tag="VQ873_000468"
     CDS             44321..45508
                     /locus_tag="VQ873_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3106794.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45501..45866
                     /locus_tag="VQ873_000469"
     CDS             45501..45866
                     /locus_tag="VQ873_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3106795.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            45882..47228
                     /gene="asnS"
                     /locus_tag="VQ873_000470"
     CDS             45882..47228
                     /gene="asnS"
                     /locus_tag="VQ873_000470"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3106796.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47381..47671
                     /locus_tag="VQ873_000471"
     CDS             47381..47671
                     /locus_tag="VQ873_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3106797.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47683..48153
                     /gene="ssbA"
                     /locus_tag="VQ873_000472"
     CDS             47683..48153
                     /gene="ssbA"
                     /locus_tag="VQ873_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3106798.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48185..48424
                     /locus_tag="VQ873_000473"
     CDS             48185..48424
                     /locus_tag="VQ873_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3106799.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48719..50119
                     /locus_tag="VQ873_000474"
     CDS             48719..50119
                     /locus_tag="VQ873_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3106800.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50121..50480
                     /locus_tag="VQ873_000475"
     CDS             50121..50480
                     /locus_tag="VQ873_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3106801.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVLDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50534..51283
                     /locus_tag="VQ873_000476"
     CDS             50534..51283
                     /locus_tag="VQ873_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3106802.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51273..51572
                     /locus_tag="VQ873_000477"
     CDS             51273..51572
                     /locus_tag="VQ873_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3106803.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51643..52578
                     /locus_tag="VQ873_000478"
     CDS             51643..52578
                     /locus_tag="VQ873_000478"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3106804.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52664..53176
                     /locus_tag="VQ873_000479"
     CDS             52664..53176
                     /locus_tag="VQ873_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3106805.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53213..53808
                     /locus_tag="VQ873_000480"
                     /pseudo
     CDS             53213..53808
                     /locus_tag="VQ873_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53909..54103
                     /locus_tag="VQ873_000481"
     CDS             53909..54103
                     /locus_tag="VQ873_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3106806.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54149..55594)
                     /locus_tag="VQ873_000482"
     CDS             complement(54149..55594)
                     /locus_tag="VQ873_000482"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3106807.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55700..57322
                     /locus_tag="VQ873_000483"
     CDS             55700..57322
                     /locus_tag="VQ873_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3106808.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57525..59483
                     /locus_tag="VQ873_000484"
     CDS             57525..59483
                     /locus_tag="VQ873_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3106809.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59655..60215
                     /locus_tag="VQ873_000485"
     CDS             59655..60215
                     /locus_tag="VQ873_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106810.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            60216..60590
                     /locus_tag="VQ873_000486"
     CDS             60216..60590
                     /locus_tag="VQ873_000486"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106811.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT        17885 a        11271 c        13718 g        17748 t
ORIGIN      
        1 gaaagacaga aattgttcaa gaattaatga ctgagttttc gttagttctt cttctaaaag
       61 ccattaaact agctcgttcg acctactact atcacttgaa acagctagac aaaacagata
      121 aggactaagg ctggcaatac caacacgatt cttatcatcg gttcctagag agtaagggaa
      181 ttcaagcatc tatgtcacgc aagggaaaca gccaagacaa cggtatgatg gagtccttct
      241 ttggcatttt aaaatccgaa atgttttatg gctatgagaa aacatttaaa tcacttaatc
      301 aattggaaca agccattata gactatattg attattacaa caataagaaa attaagttaa
      361 aactaaaagg acttagccct gtgcaataca gaactaaatc cttcggataa attaattgtc
      421 taactttttg ggggcagtac acaatacctg atagtatgcg ttttattgtg ggaagatttt
      481 cctcattttc tagtgaaatt gaactttttc taacatcttt tgatagatga cttcttaatc
      541 aattatcatt tccattgttg tttcttgggg tttcatccct tgtctttgat aaaagcggag
      601 agcaccctcg ttatcattcc agacacttag ggttagatta ttgcagccaa tttctttagc
      661 ataatagcag aaaaatgaca ataaaatagc ccctagatat tttgaaagga aagcataggg
      721 gctatatagt ttaatcaaaa taaagcaaat ctttgctggt gcttgtaaag aggtcgaagc
      781 catccttggt aacaacaccg cagtcttcaa tacgaacacc gactttacca gggatataga
      841 tacctggttc aacagagaag cacatgcctt cttcgatgac catgtcgttt ccttccatga
      901 tagatgggaa ttcatggaca tccataccga taccatgccc gagacggtga ttgaagtact
      961 caccataacc agctttttcg atgacctcac gggcagcgcg gtccacttca tgagcagtca
     1021 cacctggctt gataaagtca agagcagctt gttgggcttc aagagtcaag ttgtaaatat
     1081 ctttcttgaa ttggtctggt ttgccgacag cgactgtacg agtcatatct gacgcatagc
     1141 cattgaccag aacacccagg tcaaagagga gaagagcatc attttcaacc ttattagctg
     1201 ctggaatgcc gtgtggattc gcagcattat caccagtcaa gaccatggta tcaaagctca
     1261 tttcataacc ttcacgtttc atggcaaagt cgatttgtgc gatgatatct gtctcagtct
     1321 tatcaagaga aatattgtca aaaccaacat gaacagcctt gtcagcataa agacctgcaa
     1381 ccatcatttt ttgcacttca tcagctgatt tgatgaggcg catgcgttgg atacgaggag
     1441 tgaggttgtc aaactcagca gtctcaaaaa ctgttttcaa accatggtat ttggtcaaga
     1501 tgagattgtc aaactcaaca gcgacacgtt tgaagtcaag ttgtggaaga gcatgtttga
     1561 ttttttgcca tggattttca gaatcgacat agcccactac tgggaaggaa acggtgctac
     1621 ttgcacgttc tacttcaaga gctgggacaa agaggagagg ttcctgatcc gctaggacaa
     1681 agaggaacat ttggcgttca tggggatcac tgtaaaaacc agtgaggtaa ttgattgtga
     1741 cggggtcaga tacgacagcg acgtctagtt tttctgattc aagatatgtt aggatttgtt
     1801 gtaatttaga catatgctac cttctttcta cccctctatt ttggcaaaaa atgagagaaa
     1861 atgcaaggga gaagggtaaa agaaaagaca aaaaactccg acaagataac ggagttcttt
     1921 gatatcattt tcctttgttt aagaaaagtc agccttgctt ttgacgtcac tgtactcttc
     1981 agcgatttct tggctgagga tatcctcata ggcagggagt tggatatcct gaccatattt
     2041 cttcttgagg gcagtagtaa ctaggcgata agccagattg gcattacgag agaggatagg
     2101 cccgtggaag taggaaccaa agacattctt ataatgaacc ccttcaccga ccttttcttc
     2161 gttgtttcca tttccataga caacctgtcc cagcggtttt tggtcatcag agaggaaggt
     2221 acggccttgg tgattttcaa atccatagta ggtttcatcg aaatcttcat tgtgaatctt
     2281 gatgtcaccg ataaaacggt tattggtctg gttgagcgtg tagtgtccca tgacccctag
     2341 cccttcgata cgttttcctg aagcttcaac ataatattga cccaatagtt ggaaaccacc
     2401 gcagatagcc agaactacac cgtcgttttg gatgtagttg tcaatgctct cttttttagc
     2461 aggtaggtcg tctgcaatga tactttgttc aaagtcttga ccaccaccga aaaaggcgat
     2521 gtcgtagtga ttttcatcaa agtcatcatg gagagaaacg atgtcaacgg tcacatgggc
     2581 tcccagtttt tcagccacat atttgagcat gaggatgttt ccattgtccc cgtaggtatt
     2641 catgagattt ccgtagaggt gggcaatgtt gagctgatag gggtaattgc catcttttga
     2701 ggaaagtgaa gtataaacca ttagttcatc tcctttctaa caatctgacg actagccagc
     2761 agttcacgaa attccagcat ggcagtataa gttgccagaa tataggcatg cttgcagtct
     2821 tgattctcaa tggtcttgag aacttgctcc agattactcg tttcagtgat tttctcagct
     2881 ggatagccag tcactcggag gcgacgagcg atttcagaat gacgaacacc gccagcgttg
     2941 atttcaggaa tgtccatgtc agtgatttgc tcaaagtctg catcccagat ccagctagtg
     3001 tcaattccat ctgcatagtt ggcattaagg aggacagata ggctaaatgg ataaggtgct
     3061 agtttgatca tttcgatagc ttgggttgca ccgactggat ttttaatcaa gacaagggta
     3121 catttcttgt caccgatatg aaaggtttct tggcgtccaa agacagcacg gctcttgtca
     3181 aatccctgtt tgatgagttg cgaatcggca cctaggaaac gggcgatggc cacagcagct
     3241 agggcgttat agatattata gagcccgccg atttggatac cgtattcttg gccgtctatg
     3301 acaaagcgag agcgattgtt ggtcaactca accagttttg tcaaacgata gtcgagatca
     3361 ggacgtttac atccacaacc ttcacagata taggcaccca agtttgcata ggtattatgc
     3421 tcatatttga ggatgccttg gcagtcagga cagagaatcc cttcggtatt gtagtgagcc
     3481 agttgggctg gtcctttttc caagtcaaaa ccaaaatact ctatagggtt tggaatagtt
     3541 ggcttgtaga aaagtggact gtctccgtta aggagaacag tagcagttgg aacttttcga
     3601 atggcatcca atatcatgtt ataggtagta tagatttcac cgaaacggtc catctggtca
     3661 cggaagatat tagtaatgac aaaaagacta ggctggatat agtcacagat acgagataga
     3721 ctggcttcgt caatttcgag gacggcaata tttttcccag tttttgaaga tttggctgtt
     3781 aggaaggttg ttgcaatccc tgtaatcatg ttggcaccgc ttgggttggt tagaacttga
     3841 ccataaacct cttttaaaat gccgacagtg agggcagttg tcagggtttt tccatttgtt
     3901 ccagtgacaa cgacaatctc gtagttctta gctaggtttt gtaaaatatc tttatcaaat
     3961 tgaagggcga ctttacctgg gagcgtactt ccacgtccaa gacggcttaa aacgaagtgg
     4021 gaagaacgcc cagcaagaag gcccaaagta gtttttaagt tcatgtttct attatatcac
     4081 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     4141 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     4201 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     4261 cagtaatgat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     4321 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4381 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4441 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4501 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4561 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4621 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4681 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4741 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4801 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccaggt
     4861 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4921 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4981 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     5041 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     5101 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     5161 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatattgacg ccagtaccag
     5221 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     5281 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     5341 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5401 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5461 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5521 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa gatgaaaacg ctttccagac
     5581 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5641 taaagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5701 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5761 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5821 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5881 cgaaagtcat gggaagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5941 ttgcaataga ccgtcaggag ctgtggttgt tgtatctcgc ttatggcatt ttaggtgggc
     6001 ttggtttggg agcaggctat attacccctg tgtcgacgat tataaaatgg tttcctgata
     6061 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     6121 gtcccatagc gcaacacctc atcgcagggg tagggcttgt agaaactttt tatattttag
     6181 gagcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     6241 aagagcttgc aattttatct tcttcaggga aagaaaaaac agcctctttg acgcaaggaa
     6301 tggctgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6361 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6421 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtgt tttggggatt ttcaatggat
     6481 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6541 tattactgct tgttaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6601 tatttgtagt cgctatgtct attttgatga cttgctatgg agctggtttt tcattgatcc
     6661 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggatatattt
     6721 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6781 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6841 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6901 tttctgtaga aatgggacta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6961 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     7021 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     7081 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctggcag
     7141 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     7201 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     7261 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gccttagtca
     7321 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7381 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7441 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7501 aacgcaaggc cttgaaatta caaaacattg aaacccttat ccttgacgaa gcggatgaaa
     7561 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7621 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7681 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7741 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7801 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7861 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7921 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7981 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     8041 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     8101 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     8161 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     8221 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     8281 gtgccaattt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     8341 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8401 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8461 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8521 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8581 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8641 gctttgttat tcgtaacaaa ggtgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8701 tttatataag gagaccgaat gtgaaaaaga caaataaaat tattatatta tcttttataa
     8761 tattatgata cacaaaaata ggcaacttgt caatagaaaa ggaacaattt aattaaaaat
     8821 attctggttt ttaattaaat tgtaagtcaa tgcaagtcaa taaggaattt tcagataatt
     8881 attgaaaaag agacgttttt atgttataat gatagcgatt aaattcgagg tgaaaaatgg
     8941 cacatttatt agaaaaaact agaaaaatta catcaatttt gaaacgctca gaggagcagt
     9001 tgcaggatga gcttccttac aacgctatta cgcgtcagtt agcggatatt attcattgca
     9061 atgcctgcat tatcaatagt aagggacgtc tgcttggcta ttttatgcgt tataaaacaa
     9121 atacagatcg cgtagagcaa ttcttccaaa ctaagatttt cccagatgac tacgttcaag
     9181 gggctaatat gatttacgaa acagaagcaa acttacctgt tgagcatgat atgagtattt
     9241 tccctgttga gagtagagat gattttccag atggcttgac gactattgca ccgattcatg
     9301 tatcggggat tcgccttggt tctttgatta tttggcgtaa tgataaaaaa ttcgaagatg
     9361 aggacttggt tcttgttgag attgccagta ccgttgttgg gattcagctt cttaacttcc
     9421 aacgtgaaga agatgagaaa aatattcgtc gtcgtactgc tgtcaccatg gcggtcaata
     9481 ccctttctta ctccgaactc cgtgctgttt cagcaatttt aggggaatta aatggaaatg
     9541 aagggaagtt gactgcgtca gtgattgcag atcgtatcgg aatcactcgc tctgtgattg
     9601 tcaatgctct tcgtaaactt gagtctgcgg ggattattga aagtcgctca cttggaatga
     9661 agggaaccta tcttaaggtc ttgatttcag atatttttga agaagtgaag aaaagagatt
     9721 actaatgaca aaggctttaa tttcgattga ttatacagaa gattttgttg ctgatagtgg
     9781 gaaactaaca gcaggtgctc cagctcaggc gatttcggat gccatcagca aggtaactcg
     9841 attagctttt gaacgaggag attatatctt ctttactatt gatgctcatg aagaaaacga
     9901 ttgtttccat ccggaaagta agttatttcc tcctcataat ctgattggga cgagtggacg
     9961 gaatttatat ggagatttgg ggaactttta tcaagagcat ggttcagaca gtcgtgtctt
    10021 ttggatggat aaacgccatt actcagcttt ttcagggact gacctagata ttcgtttgag
    10081 agagcgtaga gtgtctaccg ttatcttaac aggtgtcttg acggatatct gtgtcctaca
    10141 tacagctata gatgcctata atctaggata tgacatcgag attgttaaac cagctgttgc
    10201 ttccatctgg cctgaaaatc atcaatttgc cctaggtcat ttcaaaaata cactcggagc
    10261 taagttagta gatgaaaatc taaatgaact ttctgagtaa cctggttggt gaaaatgaaa
    10321 aaatttgaaa aaaagtgttg acaagcatcc caaaagttga tatactagta aagtaatcga
    10381 tgcggggatg gcggaattgg cagacgcgca ggactaagga tcctgtgacc gctttaggtc
    10441 gtgagggttc aagtccctct ctccgcatag gaaaagagtt agctaaagct agctcttttg
    10501 tatttctcta aaaaattaga atccagtcaa atgtagtgga gaatcagcga aaatatggga
    10561 aaactgatcc ttgtttctgc ttttgtcata gaagaataat aaagattatc ttcttcaaat
    10621 tctccgatat tctctaaagt tttgtgcaag ttgcacagaa cttttttatt tttttggtca
    10681 tcttgccata gaaatataaa gcgttttcat atataatata attatcaaaa gacaaaagga
    10741 gttcacctca tggtagaatt gaatcttaaa aatatttaca aaaaatatcc aaacagcgaa
    10801 cactattcag ttgaagattt caacttgaac atcaaagata aagaatttat cgttttcgta
    10861 ggaccttcag gatgtggtaa atcaactaca ctccgtatga ttgctggtct tgaagacatt
    10921 acagaaggta ctgcatctat cgatggcgtg gttgtcaacg acgtagctcc aaaagaccgt
    10981 gatatcgcca tggtattcca aaactacgct ctttacccac acatgactgt ttatgacaac
    11041 atggctttcg gtttgaaatt gcgtaaatac agcaaagaag acattaacaa acgtgttcaa
    11101 gaagcagctg aaatacttgg attgaaagaa ttcttggaac gtaaaccagc tgacctttca
    11161 ggtggtcaac gtcaacgtgt tgccatgggg cgtgcgattg tccgtgatgc gaaagtattc
    11221 ttgatggacg aacctttgtc aaacttggat gccaaacttc gtgtatcaat gcgtgctgaa
    11281 atcgctaaaa ttcaccgtcg tatcggagct acaactatct atgtaactca cgaccaaaca
    11341 gaagcgatga cacttgcaga ccgtatcgtt attatgtcag ctactaagaa ccctgctggt
    11401 acaggtacta tcggacgtgt agaacaaatc ggcactcctc aagaagttta caaaaatcca
    11461 gttaacaaat tcgttgcagg attcatcgga agcccagcta tgaacttcat caacgtgaaa
    11521 ttggttggta gcgaaattgt ttctgacggt ttccgtttga aagtgccaga aggagcattg
    11581 aaagttcttc gtgaaaaagg ctacgaagga aaagaattga tctttggtat ccgtccagaa
    11641 gacgtgaatg cagaacctgc tttccttgaa acattcccag actgtgttgt aaaagcgact
    11701 atctctgtat cagaactgct tggttcagaa tctcaccttt actgccaagt tggtaaagac
    11761 gagtttgttg caaaagttga tgctcgtgac tacttgcaaa caggtgcaac agttgagctt
    11821 ggatttgact tgaacaaagc acacttcttc gatgtagaaa ctgaaaaaac aatctactaa
    11881 aataaataaa attcaaagca ctacaagaaa agatatttct ttatcaattg tagtggagag
    11941 atatcagtta atctagggag agaaacaaaa tgcttctctc ctttttgcta gggaagtcat
    12001 attatgcatc tatattgtga tgctctttaa tactcttcga aaatctcttc aaaccacgtc
    12061 aacgtcgcct tgccgtacgt atgattactg acttcgtcag ttttatctgc aacctcaaag
    12121 ctgtactttg agcagtttac ggctagtttc ctagtttgct ctttgatttc cattgagtat
    12181 tatttgtggg taccatctac aagtgaagct atatgcgtaa actacgtgag caattgaatt
    12241 cgaactagag aggtaataat aaatttatgc tatagttatg gtgacttgta tgcttttgat
    12301 tctagtttat caaataatag attagaattg tcagataata tcattttgtg ttataatgaa
    12361 gaaaaaacag aggtgttcaa atgtcagaag caggtcataa gtttttagca aaattgggga
    12421 aaaaacgctt acgtccaggt ggaaagcgtg ccacagattg gttaattgca gaaggaggat
    12481 tttcaaaaga aaagagaata ctagaggttg cgtgtaatag gggaactaca gcaattgagt
    12541 tggcacagcg ttttggttgc aagataactg ctgttgatat ggatgctcaa gctttagaag
    12601 tggctaaaaa atctgctgga acggcaggtg ttgctcattt aatcagtttt gaaagagcaa
    12661 atgcaatgaa acttccttat caagatgcta gttttgatat tgttataaat gaagctatgc
    12721 tgactatgca agccgatcaa gctaagaaaa aatgtgtaat ggaatatcta agggtattaa
    12781 aacctggagg tcttctcttg acacatgatg tacttcttaa ggaagctaaa gagtctatca
    12841 gacaggaatt atcacaagca attcatgtaa atgtaggtcc tttaactcaa gatggttggg
    12901 aacaggtgat gatagaatca ggttattgtg atgtgaaagc attgactggt gaaatgacat
    12961 taatgaaatt atcgggtatg atttatgacg aaggtttgct aggaactttg aaaatttgtg
    13021 taaatgcttg taaaaaggag aatagaaagc agtttttaac tatgtataaa atgtttgcta
    13081 agaataaaca gaaattgggc tttattgcga tggctagtta taaatcgtca aaacgttaga
    13141 taattattga agttaacttt tccttttttc tttcttaaaa aatatgctat aatagagagt
    13201 aaaaaacttt gaaagaaaga aaaagatgaa tttaaaagat tacattgcaa caattgaaaa
    13261 ttatccaaag gaaggcatta ccttccgtga tattagtcct ttgatggctg atggaaatgc
    13321 ttatagctac gctgttcgtg aaatcgttca gtatgctact gacaagaaag tcgacatgat
    13381 cgtgggacct gaagctcgtg gatttatcgt gggttgtcca gttgcctttg agttgggaat
    13441 tggttttgcg cctgttcgta agccaggtaa attgccacgc gaagttattt ctgctgacta
    13501 tgaaaaagag tacggtgtcg ataccttgac tatgcacgcg gatgccatta agccaggtca
    13561 acgtgttctt attgtagatg accttttggc gacaggtgga actgttaagg caactatcga
    13621 gatgattgaa aaacttggtg gtgttatggc aggttgtgcc ttccttgttg aattggatga
    13681 attgaacggc cgtgaaaaaa ttggtgacta cgactacaaa gttcttatgc attattaatg
    13741 aaaacagtcc ctagggctgt tttctctaca ctaggatata aaaatagact ataactagtt
    13801 agagaaaaac tataattgaa aactatatct tcttacagta taataaaagg actaagtgtt
    13861 tgagatttgt cttcaaacat atgcaattat tcctgaaaga gtacagttag gagagggtta
    13921 tgccgattcg aattgataaa aaattgccag ctgttgagat tttacggaca gagaatatct
    13981 ttgtcatgga tgatcaacgt gctgcccacc aagatatccg tcctttgaag attttaattt
    14041 taaatctcat gccacagaaa atggtcacag agacccagtt gttgcgccac ttggctaata
    14101 cacccctaca actggatatt gattttctct atatggagag ccaccgttct aaaacaactc
    14161 gttcagagca catggagacc ttctataaaa cttttcctga agtcaaggat gagtattttg
    14221 atgggatgat catcacgggt gctccagttg agcatttacc atttgaggaa gtggactatt
    14281 gggaggaatt tagacagatg cttgagtggt ctaagactca tgtctattcg acccttcata
    14341 tctgttgggg ggctcaggct gggctttatc tgcgctatgg tgtagaaaaa taccagatgg
    14401 acagtaagct atcaggtatt tatcctcagg acaccctaaa agagggtcac cttctattta
    14461 gaggctttga tgatagctat gtatcccctc attcacggca cacggagatt tctaaggaag
    14521 aggtcttaaa caagaccaat ctcgagattt tatcagaagg acctcaggtt ggggtttcta
    14581 ttttggccag tcgtgattta cgagaaattt atagttttgg tcatttggag tatgaccgtg
    14641 ataccttggc aaaagagtat tttcgagatc gtgatgcagg tttcgaccca catattccag
    14701 aaaattactt taaagatgat gatgttaatc aggtaccttg tctttgttgg tcttcatctg
    14761 cagccctctt tttcagtaat tgggtaaacc atgcggtcta tcaggagacg ccttttgatt
    14821 ggagaaagat agaagatgat gcatctgcat atgggtattt ataagaggaa ttatgacata
    14881 tttagacgct tttaaatcag gtatcttggt tttaccgagt gccctgctct tgcattttaa
    14941 ggaactcttt ccttctagcg acgattttct ggtttggcaa tttttctatt tgcaaaatac
    15001 gacaggctta gaagaaatgt cgccaagcca gattgctgaa aggattggca aggaaatttc
    15061 ggatgtcaac cagtccattt ctaatctgac ggaaagggga ctgctccagt atcgtactat
    15121 cgaattaaat ggcgaaattg aattgctctt tgatgctagt ttggccttgg aacgtttgga
    15181 tgacctgttt ggagcagttc attcaagttc agaccagctg acacctcaaa accagctcaa
    15241 ggatttggtg gaaaccttcc agcaggagtt gggacgattg ttgacgcctt ttgagattga
    15301 ggatttgacc aagacactaa aggaagatgg aaccagtgct gacttgatta aggaggctct
    15361 tcgtgaagct gttttgaatg gaaaaccaaa ctggaagtac attcaggcga ttttgagaaa
    15421 ctggcgccat gaaggaatca agagtgtggc tcaaattgag gccaagagag cagaaagaga
    15481 agcaagcaat cctcagttga cacaggtatc tgcagatttc ataaatgcca tggatctctg
    15541 gaaggattaa tccatgcaag taggcttgaa atccgagtaa gatttgcaag ctgtgtataa
    15601 ttgtgataga ataaatagaa aataaattga aaaaagaggt atgtgaaatg tcacgtaaac
    15661 catttatcgc tggtaactgg aaaatgaaca aaaatccaga agaagctaaa gcattcgttg
    15721 aagcagttgc atcaaaactt ccttcatcag atctggttga agcaggtatc gctgctccag
    15781 ctcttgattt gacaactgtt cttgctgttg caaaaggctc aaaccttaaa gttgctgctc
    15841 aaaactgcta ttttgaaaat gcaggtgctt tcactggtga aactagccca caagttttga
    15901 aagaaatcgg tactgactac gttgttatcg gtcactcaga acgccgtgac tacttccatg
    15961 aaactgacga agatatcaac aaaaaagcaa aagcaatctt tgcgaacggt atgcttccaa
    16021 tcatctgttg tggtgaatca cttgaaactt acgaagctgg taaagctgct gaattcgtag
    16081 gtgctcaagt atctgctgca ttggctggat tgactgctga acaagttgct gcctcagtta
    16141 tcgcttatga gccaatctgg gctatcggta ctggtaaatc agcttcacaa gacgatgcac
    16201 aaaaaatgtg taaagttgtt cgtgacgttg tagctgctga ctttggtcaa gaagtcgcag
    16261 acaaagttcg tgttcaatac ggtggttctg ttaaacctga aaatgttgct tcatacatgg
    16321 cttgcccaga cgttgacggt gcccttgtag gtggtgcgtc acttgaagct gaaagcttct
    16381 tggctttgct tgactttgta aaataatcag taagtagcaa aagctaggtg gaacagcatt
    16441 cagatgtctg ttacattttt tataggagag gaaagattga aaacaaaaat tggattagca
    16501 agtatctgtt tactaggctt ggcaactagt catgtcgctg caaatgaaac tgaagtagca
    16561 aaaacttcgc aggatacaac gacagcttca agtagttcag agcaaaatca gtcttctaat
    16621 aaaacgcaaa cgagcacaga agtacagact aatgctgctg cccactggga tggggattat
    16681 tatgtaaagg atgatggctc taaagctcaa agtgaatgga tttttgacaa ctactataag
    16741 gcctggtttt atattaattc agatggtcgt tactcgcaga atgaatggca tggaaattac
    16801 tacctgaaat caggtggata tatggcccaa aacgagtgga tctatgacag taattacaag
    16861 agttggtttt atctcaagtc agatggggct tatgctcatc aagaatggca attgattgga
    16921 aataagtggt actacttcaa gaagtggggt tacatggcta aaagccaatg gcaaggaagt
    16981 tatttcttga atggtcaagg agctatgatg caaaatgaat ggctctatga tccagcctat
    17041 tctgcttatt tttatctaaa atccgatgga acttatgcta accaagagtg gcaaaaagtg
    17101 ggcggcaaat ggtactattt caagaagtgg ggctatatgg ctcggaatga gtggcaaggc
    17161 aactactatt tgactggaag tggtgctatg gcgactgacg aagtgattat ggatggtgct
    17221 cgctatatct ttgcggcctc tggtgagctc aaagaaaaga aagatttgaa tgtcggctgg
    17281 gttcacagag atggtaaacg ctatttcttt aataatagag aagaacaagt gggaaccgaa
    17341 catgctaaga aagtcattga tattagtgag cacaatggtc gtatcaatga ttggaaaaag
    17401 gttattgatg agaacgaggt ggatggtgtc attgttcgtc taggttatag cggtaaagaa
    17461 gacaaggaat tggcgcataa cattaaggag ttaaaccgtc tgggaattcc ttatggtgtc
    17521 tatctctata cctatgctga aaatgagacc gatgctgaga atgacgctaa acagaccatt
    17581 gaacttataa agaaatacaa tatgaacctg tcttacccta tctattatga tgttgagaac
    17641 tgggaatatg taaataagag caagagagct ccaagtgata cagacacttg ggttaaaatc
    17701 atcaacaagt acatggacac gatgaagcag gcgggttatc aaaatgtgta tgtctatagc
    17761 tatcgtagtt tattacagac gcgtttaaaa cacccagata ttttaaaaca tgtaaactgg
    17821 gtagcggcct atacgaatgc tttagaatgg gaaaaccctt attattcagg agaaaaaggt
    17881 tggcaatata cctcttctga atacatgaaa ggaatccaag ggcgcgtaga tgtcagcgtt
    17941 tggtattaag cgatgatttg aaagagggat gtgatagtag caccctcttt ttctttgttt
    18001 tatgatagtt catcctcgag taaattcaag atcttgctcg gaaatgaagc ttatatagta
    18061 gattgaatat agacaaagac cttgtgattg gtaaaacatt ttagaaattc atttaccttt
    18121 cctaatcgac ttggtttcat cttatttcaa tctattatag tattggggaa tttcttcaaa
    18181 ccacatcagc ttggtcagtt ctacctgcga cctcaaaact tgtgctttgg tcaagctggg
    18241 tttagtttcc tagtttgctg atggatttcc attgactata agcatccaac cctctttttt
    18301 gtcttctaaa gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg
    18361 tcttgctatt agttttcctt agtagtatac taaggtagta atcattaaga agtggttaca
    18421 aaaaataatg aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt
    18481 aacatcattg acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca
    18541 agctgttgct gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca
    18601 tggtcgtggt ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg
    18661 tcaattggat gaaatcagcg aacgcttgat tacactcggt ggaagcccat tctctacatt
    18721 gacagagttc cttcaaaata gtgaaatcga agaagaagct agtgaatacc gtaatgttga
    18781 agaaagcttg gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg
    18841 tttggatgtc actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa
    18901 aactgaaaca gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt
    18961 gtaagaaata aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt
    19021 tgtaagctat tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga
    19081 aaaggatgga agtatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt
    19141 gattggtaag gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga
    19201 aacaactctg aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg
    19261 cttgcttcca aaacgggaaa ccttgatttt gacgcgtaat ccggaagaaa agatagatgg
    19321 ggttgctact tttcaggacg tccagtctgt tcttgactgg tatcaggctc aagaaaagaa
    19381 tctctacatt attggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt
    19441 gattgtcact cacattcatg ctcgtgtgga aggagatacc tatttccctg aagaacttga
    19501 cttgtctctt tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta
    19561 tgattttacc atccaatacc gcaagagaaa ggaactctaa tggaacggag tttatttggt
    19621 ctattcacgg cttttctgtg tttcatctgc tttctggcag gagcacaagc ttttcgtaaa
    19681 aagcgttacg ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt
    19741 attcatgctt tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat
    19801 catgtctaca aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca
    19861 agaagaagta caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga
    19921 gttagctcag gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga
    19981 ggtgccaaaa ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg
    20041 tgccaagcgt gccttggcag tggcggttta taaccactac aaacgcatca atttccacga
    20101 tacacgcgaa gagtcagaag atgtagattt gcagaagtca aacattttga tgattggccc
    20161 aactggttca gggaaaactt tccttgccca gaccttggct aagagcttga atgtgccttt
    20221 tgctattgcg gatgcgacag ctctgacgga ggctggttat gtgggtgagg atgtggaaaa
    20281 tatcctcctc aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat
    20341 tatctatgtg gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg
    20401 tgatgtttct ggtgaagggg tgcaacaagc ccttctcaag attatcgagg gaactgttgc
    20461 tagcgtgccg cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac
    20521 aaaaaatatc ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca
    20581 acgtctgggt gaaaaagtca tcggatttgg tcaaaacaat aaggcgattg atgaaaacag
    20641 ctcatatatg caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt
    20701 gattggacgc ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg
    20761 catcttgaaa gagccaagaa atgccttggt gaaacaatac caaaccttgc tttcttatga
    20821 tgatgttgag ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga
    20881 acggaagaca ggggcgcgtg gacttcgctc catcatcgaa gaaaccatgc tagatgttat
    20941 gtttgaggtg ccgagtcagg aaaatgtgaa attggttcgc atcactaaag aaactgtcga
    21001 tggaacggat aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatatacac
    21061 aatgctgaaa tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca
    21121 gagattgccc tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg
    21181 aaccgtaaga atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt
    21241 tttaacattg atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt
    21301 tctaaaaagg aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa
    21361 aatctccgtg cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg
    21421 cagatgtacg aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg
    21481 gacaagattc ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac
    21541 tttgacccaa gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag
    21601 gcttgggatg caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac
    21661 agataaggcc ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt
    21721 gtttgctagc ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat
    21781 ccaagaacag acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac
    21841 agactttgac catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc
    21901 ttttaatgag gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga
    21961 ggtagctcgt cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata
    22021 agctagttga agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa
    22081 gaaacaactt cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat
    22141 tcagtccttc gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc
    22201 taagtttttg cagctggttg aaattaagga agacaatcct aagttggcct tggtagtgga
    22261 tatgcgtagc cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca
    22321 agatggtttg gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg
    22381 ttacaaggaa accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat
    22441 caagttggaa cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac
    22501 gactgaactc actccacgtg agctgcgcaa aacccttgca gagcagtttt cagaccaaga
    22561 acaagcccag tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat
    22621 tgatgcggac ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact
    22681 gagaaaccaa acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc
    22741 agaagacttt tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa
    22801 ggaaggtaag tccgttttga ccattgccat gggatgtacg ggtggacaac accgtagtgt
    22861 ggcatttgct aaacgcttgg cgcaggactt atccaagaat tggtctgtta atgaagggca
    22921 tcgcgacaaa gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg
    22981 gtgattggtg gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg
    23041 gaaatcgcag ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa
    23101 aatatgcaac agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat
    23161 atgcctaagt tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt
    23221 gctggccatc cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc
    23281 tataatgcca tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc
    23341 agtgaccatc ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggttggagag
    23401 agtcatattg tagaccatcg aggcataatt gacaatgtct atgtgactaa tgctctaaac
    23461 gatgatacgc ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt
    23521 gtcctagggc caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt
    23581 gggcgggctc ttttggaaac caaggcagaa attgcctatg tctgcaatat tatgacccaa
    23641 cgtggagaga cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt
    23701 ggtcgccctt ttatcgacac tgtcttggtg aatattgaaa aagtgcctca gaaatacatg
    23761 aattccaacc gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt
    23821 aagcaagttt cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc
    23881 cacgatggag atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt
    23941 tcacagtagc agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat
    24001 ctgccattat caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag
    24061 ttgtgacaga aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg
    24121 aaatcaaatc tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata
    24181 ccgtttttac agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt
    24241 tctttggctt ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg
    24301 cctatctctg tggcgctttc ttggcaaatg ggagcattcg tgaccctgag tcaggcaagt
    24361 accagttgga aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc
    24421 aacagttttt actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc
    24481 agcgagcaga agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg
    24541 attttgagcg ggttaagatt ttgcgagaaa ctcgtaacga cctcaatcgg gctaataatg
    24601 ccgagacagc taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca
    24661 gtaaaatcaa agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc
    24721 aactgaggat tcagcaccca gactactcta tccagcagtt agcagatagc ctcagcaccc
    24781 ctctgaccaa aagtggtgtc aatcacagac tcagaaaaat caataagata gccgatgaat
    24841 tataaaacca cgaatcctat gtgactcgtg gttctttttt ataaactagt agagtgtttt
    24901 ggttgtactt tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct
    24961 tctccgaggc ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata
    25021 gcatagatac ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg
    25081 aggtcgagcc cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag
    25141 aggtggtcta ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta
    25201 tcaagtgttt ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca
    25261 gatgattctt gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga
    25321 acaagggtag ttggtgcgat tttttcaaaa gccaaagccc aatccacagc cgagtctccc
    25381 ccaccaagaa tcgtcacttt cttaccagcg tattgctgaa tgttagaaac gtggtagtgg
    25441 atattttcat agccctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca
    25501 cccatagcga tgatgactgt tttagtcaag tgacttcctt tagaagttgt gatggcaaat
    25561 tcttcttctt gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat
    25621 ccatttagct gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct
    25681 ggtacgtcta ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga
    25741 agagagtcga tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc
    25801 ccgacaggac caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg
    25861 ttttttctag tcagtttatt ttatcatatt tttgttcaat gtaaactgga ctaggatagg
    25921 gaaaaaaatg ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag
    25981 ggatgaattt tcaacaatta tccaatctgc aatattggac cagtttgttt gcaagtccat
    26041 ggacgatagc tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta
    26101 caaaagctat tgcaggaacc aagattatga ttttggtacg tggagttttg gtgtttattt
    26161 tagctcaaat ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa
    26221 ttattactta tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt
    26281 tggaacgttt gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac
    26341 agatgattcg tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct
    26401 tggttgctat tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg
    26461 atgctaagat ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg
    26521 atggtgcggt gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga
    26581 caaaaaacac agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat
    26641 cagaagtctc agatgccttg acttttgttg tatcagagga aacgggagga atttcgataa
    26701 cctataatgg aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg
    26761 aaatcttact tccaaaagag gaagtgggtc ttagttttaa agaacgattg ctaggaggat
    26821 ggaaacatga aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta
    26881 tttgtctatg ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg
    26941 gaaacctata ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag
    27001 tattttatta gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta
    27061 tcgctagcta gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca
    27121 gatgccggtg ttggaacgat tgaagttcct ttgagcattg aagatttacc caatgggctg
    27181 accgctgtgg cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat
    27241 aaggtaaaga ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa
    27301 aatgtcatgg tgtcagataa agaagtgtct attacgagtg accaagagac attggataga
    27361 attgataaga ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt
    27421 tcagtacctt tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg
    27481 tttgatacaa taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat
    27541 tcaagtacaa gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg
    27601 aattaaaaat agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc
    27661 gtggagaagc taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag
    27721 gctatgttct tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac
    27781 gtatttcagg ggaaatgctg gaatcggcct tggtggcagg tctcctttca gtagggattc
    27841 acgtatacaa acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag
    27901 gagcaagtgc cggtgtcatg atttctgcta gccacaaccc agcccttgat aacggaatca
    27961 agttctttgg cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct
    28021 tgctagatgc tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaatcttgg
    28081 tagattatcc agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc
    28141 ttgatggaat gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc
    28201 aaatctttgc agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta
    28261 acatcaacct taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa
    28321 gtgggtcagc tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg
    28381 agaatggtga catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg
    28441 aaaaaggaca attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc
    28501 acaaggcctt gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg
    28561 ttgttgaaga aatgagaaaa tcaggctaca accttggtgg tgaacagtct ggtcacgtta
    28621 tcttgatgga ttacaatacc acaggtgatg gtcaattatc agcagttcaa ttgactaaaa
    28681 tcatgaagga aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac
    28741 aaaaattagt taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag
    28801 ctatcaaggc catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg
    28861 ttcgtccaag tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag
    28921 aagtagacta ctatgttgat accatcacag atgtagttcg tgctgaaatt gggattgatt
    28981 aaatcctaga aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag
    29041 ccgatggaga aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt
    29101 gatgcgcgta attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg
    29161 aatttccaat tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcatcttg
    29221 agctttatga ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat
    29281 atcgatggcc gtattgtcaa tgaaccaaat gaattgaacc aagaagaggt ggaaaccttg
    29341 gctcgtccat gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta
    29401 gacttaccag gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc
    29461 tgcttatctc agtgcagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt
    29521 caatattgat ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca
    29581 aaaaatggct caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga
    29641 tgaaatctta acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc
    29701 ttctggaatt tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt
    29761 aaccattgct ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag
    29821 cgtctttaat tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat
    29881 tcaaatcagc cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg
    29941 tggacgtctt tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct
    30001 ttattttaac gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc
    30061 caccaagcgc ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat
    30121 tgtcattcat gggaatgctc ctgaaaaggc tgaagaattg cgtcagcatt tgcttgattt
    30181 tggcttgggt tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg
    30241 agcaggaagt attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt
    30301 aagatgcctt gtatcttagc aattgaacac ggactacctg cttcttgaaa aaagatgcct
    30361 gtcttgcctt tcgtggaaag tcagtgccat tccctatttt tcaggggcag ctaaggtcct
    30421 ttgtatcttg ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga
    30481 agtagacact tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc
    30541 ttagacagga gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg
    30601 ccaggctgct tgtcagatgg tattgactga tccagacttg gacttggtag cagttttgga
    30661 tccttttgag tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt
    30721 agcttgtttt gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa
    30781 tacacgtttt gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag
    30841 tgaagaaatt gcagagctaa aagaattttc tcgtacccaa gacttgggtg gcctgattgc
    30901 ccctaacttt gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata
    30961 tttcccaaat gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg
    31021 aacagccatt aaaacagctg agttgatggc agagattcga gagtcaattc agcaaggtgc
    31081 agcagatgag gaagagctga ttgctggtgc tcgtggtgct gactttgatg gtatgcgcat
    31141 ccactcagtt cgtttgccag gtttggtagc ccatcaggaa gtcatctttg gcaatcaagg
    31201 agaaggattg accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa
    31261 tttgggaatt aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt
    31321 atgagattaa tgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt
    31381 aaagaagcag gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat
    31441 agccctatcc acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt
    31501 tttccgcgaa cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat
    31561 gaggagtatg aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc
    31621 agtgcggttt cctttgtgcg ctcgctagaa gaagacctca aacgccgtga tttcacagtc
    31681 aacgcctttg ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat
    31741 ttggaaaagc aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct
    31801 ttacggatta tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgaaccagaa
    31861 acatttaaag ctatgaagac cttgacgccg cttttggaga acatttctgt agagcgtacc
    31921 ttcgtcgagt ttgataaact cttgctggct ccattttgga gaagggggtt ggcttccatg
    31981 attgagagtc aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac
    32041 agactgtttg atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct
    32101 ttactatggg ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca
    32161 cgccagtttg ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga
    32221 gaattgagca agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat
    32281 cttcgtcaag ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc
    32341 ttgactatcc atgacaagaa agagattcag attaatggcg gtattttgat caaggaatat
    32401 ggctatcagc caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc
    32461 gatggagaat tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga
    32521 gtgattttat cgttgaaaaa ctaagtaaat ctgttggtga caagaccgtt tttagggata
    32581 tttcctttat tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca
    32641 agaccaccct tttggacgtc ctttctggtg tttctggctt tgatggggat gtcagtcctt
    32701 tttcagctaa aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata
    32761 gaaagacagt tttggatacg attctatcta gtgaactcaa ggaaatccag ctcattcgtg
    32821 agtatgaatt gattatgctc gactatagcg aggacaagca ggcgcgtttg gaacgtgtca
    32881 tggcagagat ggactctctc caagcttggg aaatcgagag tcaggtcaag accgttctta
    32941 gcaaattggg cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa
    33001 gacgggtaca gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc
    33061 cgaccaacca tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta
    33121 agaagaccgt cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga
    33181 ttttcgagtt ggagcgagca ggcttgacag aatatcaggg caattaccag gactatgttc
    33241 gccttaaggc agaacaggac gagcgcgatg cagctctact tcataaaaaa gaacaactct
    33301 acaaacaaga actggtctgg atgcgcagac aaccgcaggc acgtgcgacc aagcaacaag
    33361 ctcgtatcaa tcgtttccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag
    33421 acttgactat gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg
    33481 tttcctttgc ctatgaaaat aagcccattt tgcaagattt taatctctta gttcaggcta
    33541 aagaccgtat tggaattgtt ggggacaatg gtgttggaaa atcaacccta cttaacctga
    33601 ttgcaggaag tcttgagccg acagcaggac aagttgtgat tggggaaact gttcgcatcg
    33661 cctatttctc tcaacaaatt gagggtttgg atgaaagcaa gcgtgtgatc aattacctgc
    33721 aggaagtggc agaggaggtc aagaccagtg gtggttctac gacttccatc gctgagttgc
    33781 tggagcaatt cctcttccca cgttcgacgc atgggacctt gattgagaaa ttgtcagggg
    33841 gtgagaaaaa acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt
    33901 tagacgagcc aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc
    33961 aaggttttgc aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag
    34021 cgaccaagat tctcgctttt gaggatggca agattcgtcc tttctttggt cattacaccg
    34081 actatcttga tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggccgaaa
    34141 aggaaaaagt ggtcaaggtt cgagaagaca agaaacgcat gacctaccaa gaaaagcagg
    34201 agtgggcaag tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag
    34261 aggaaatgca ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg
    34321 atgagaaaaa tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg
    34381 atagttaata ctattcgaaa atcaaagtgt aaactatgtc ggcttcacat tgccgactca
    34441 agtacagcct gtggccggct tcctagtttg cactttgatt tttattgagt ataaaagaat
    34501 agaaaaatcc catctcatga acggatttct ctattctttt ttggtttctt gatgaaagat
    34561 attttgccag gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata
    34621 gcagatgagt ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt
    34681 taactctttt ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata
    34741 gacaaaatca tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg
    34801 cataagcaat tttttataga cattgtctaa aatttcatcc tcagggatag gtgctggttc
    34861 gatatggaca tcggtatcaa agacgccaaa acgattctcc agcatagact cgacctgatc
    34921 cgcgatttca tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag
    34981 gtagatgttg ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat
    35041 ttccatgata gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact
    35101 aaaggaagac tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat
    35161 agcaaccagt ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt
    35221 tccaagtgag gtaacagcgt cagaaagatt gtccttagca gctgctttca gcgccttgga
    35281 gttggatttc ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga
    35341 aatgattcct agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt
    35401 ttgaatggta tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa
    35461 gcttgccaaa tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg
    35521 cgccatccga atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa
    35581 accatcggcc accaaactgg atgaatgaag gagatgacca gttgctaatt tggctgcaga
    35641 caagatcaaa taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga
    35701 gatagattgc ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt
    35761 ttcaaggaaa aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta
    35821 taatagtact actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat
    35881 tttatgctga aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa
    35941 caggtctctt tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca
    36001 atgtcaagga ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc
    36061 cctgaagagg tcttgcaggc tgtggatgcg accgagcaag gtttgtcgtc aagtgaggcg
    36121 gaaaagcgcc ttgtcgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc
    36181 ttggtcaaat tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca
    36241 atcttgtcag tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct
    36301 gtggttatca tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt
    36361 gaagccctca aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca
    36421 gagattgact ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg
    36481 gtaccagcgg acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg
    36541 acaggtgaat ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt
    36601 attggtgacc gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg
    36661 ggtgttgttg tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa
    36721 gatgcggatg agactgatac accactcaaa caaaacttga acaacctttc taaggtcttg
    36781 acctatgcta tcttggccat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg
    36841 aaaaatccac ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa
    36901 ggacttcctg ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga
    36961 cattccatcg ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct
    37021 tctgataaga ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat
    37081 gcggttctac atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt
    37141 tcagttgtct tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca
    37201 accgaaacag cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta
    37261 gagaaatatc ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca
    37321 gttcacccat tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc
    37381 ttaaaacgtt gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt
    37441 acaaatctca ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca
    37501 ggtgcttata agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat
    37561 gatttaattt ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag
    37621 gctgttcgtg tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa
    37681 gacacagcgg aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt
    37741 cacgttttaa ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt
    37801 ggtcaatact ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct
    37861 tggcaaaaac aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct
    37921 ctgaaaacag ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg
    37981 gcttctgata tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa
    38041 ggacgtaagg tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact
    38101 gctgaagtat taaccatctt cctatcaacc ttgtttggtt gggatgtctt gcagccggtt
    38161 catcttttgt ggatcaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa
    38221 cctgcggagc ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca
    38281 ggtggtgttt tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt
    38341 gtttatggcc ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca
    38401 gatgccctaa cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat
    38461 gtcaagtctg tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac
    38521 tggtccatct tggtatcttt tatccttctc atggcaacaa tcgttgtaga accgcttgaa
    38581 ggaatcttcc acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc
    38641 ttctcaatga ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac
    38701 aagaatgcga tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag
    38761 gatgaagcta gtaatcaagg agcttttacg gggctaaaca gaccaacagc aggtgcccgt
    38821 ttcgaacaaa acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca
    38881 aatggtgtga aggttactat cttattggaa gaattactag aagctggttt taaggaagcg
    38941 gcttacgact tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg
    39001 aagctcaatc caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta
    39061 agagtctttg agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta
    39121 ccaagtaatc ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca
    39181 gcaccttttc taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa
    39241 tatcctatta accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa
    39301 ttggctcaga aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg
    39361 tcttggtatg gacagttagt tcaaggaaat ctttaccaag gttctgcaaa attcttggat
    39421 gcctcaagtt atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt
    39481 aagcgtggat tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg
    39541 gctttttgct acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct
    39601 ataatatagt aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat
    39661 cttattttta tctcaagtgt ctcagccggc aagtcaggag gacctttatc ttgccagaga
    39721 tttgcaggat acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat
    39781 tggggtgcag aagcgcgtga ttatctttaa tcttggcttg gttcctgtgg tcatgtttaa
    39841 cccagtgctt ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt
    39901 aggtgtgaga tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg
    39961 gcaggaacag accattacct tgacaggctt cccagctcag atttgccagc atgagctgga
    40021 tcacttggaa ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt
    40081 atttttatcg caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa
    40141 tttctcttct tcctctgtgg gcatttgtta gttgtggcaa tattatttgg ctttggcaag
    40201 gggataaacc ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat
    40261 cttgagggtt tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt
    40321 cttctcttgg cagctttggt ttccttggta acttccagca tgtttcaggc taaaaattat
    40381 gccaatgtag tcacggttac ggaaaaagac tttactgaat ttcctaagag tgacaccagt
    40441 aaggttccta tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc
    40501 ctaaccgata aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat
    40561 gggaaacctt atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat
    40621 caagccaagg gaatcggtga gtatattaag gtggacatgg taactggaaa tgcggatttg
    40681 gtggacttga agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa
    40741 cgtcacctgc gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac
    40801 gatgagggca atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt
    40861 cctcgtcctg cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc
    40921 ttatcagatg ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa
    40981 atcaactaca acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac
    41041 gtgacccaga ctaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac
    41101 acaggtgtga cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg
    41161 cgaacaggag aaatcactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa
    41221 tcagcagaag gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac
    41281 ctcaatgaca agcctctcta catcatgggc ttgaaggaca atgctggctt ggtcaaagag
    41341 tacgccctgg tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag
    41401 atgctcagca agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc
    41461 atcaatggag tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc
    41521 tttaaagttg atggcaagat atacaaggtc aaggcttcag tatccgatga ccttccttac
    41581 cttgaaaatg gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt
    41641 aagctacggt aaaaataggt ttttttcaga aagtatatgt tataataagg taaattaagc
    41701 ctaatggagg acaaagaaat gggtttttat ttgatggttg cttcaatgct actcggactg
    41761 ctcgctttga agataggttt ttctcagttc aaggagaaaa aagataaatt cttatctatc
    41821 ttaacaagtt tagctggcac agcccttgtt ctcgtggctg tctggttagg atggcccaaa
    41881 taaatagaaa aacctcggtc aaaccgaggt ttttcaaatg aatttcttgg ttgtggctaa
    41941 aaaatatgct acactatcaa tatgaaaatt ttaatcccaa cagcaaaaga aatgaacaca
    42001 gacttgccaa gtatcgaggc aattccttta aaaccagaaa gtcaggccgt gcttgatgcc
    42061 ttggctctct attctgccag tcaattggag agtttctaca aggtatcagc tgagaaagcg
    42121 gcggaagaat ttcaaaatat ccaagctttg aaaaggcaaa ctgctcaaca ctatccagcc
    42181 ttgaaacttt ttgatgggct tatgtaccgc aacattaaga gagataagct gaccgaggcg
    42241 gaacaagatt atcttgaaaa tcatgttttc attacctcgg ctttgtacgg tgttgttcca
    42301 gtcttgtcac ccatggctcc tcaccgtttg gattttttga tgaaattaaa agtcgctggt
    42361 aagactttga agagccattg gaaggcagcc tatgatgaaa ctctgaagaa ggaagaagtg
    42421 attttctctc tcttgtcatc agagtttgag actgtatttt ctaaggaaat cagagcaaag
    42481 atggtgacct taaaattcat ggaggataga ggcggtcagc tgaagattca ctcaactatc
    42541 tccaagaaag cgcgcggggc ctttctaaca gctttaatag aaaatcaagt acaaactgtg
    42601 ggggaagcac gtcgcttgaa ctttgctgga tttgtttacc gagaagattt gtcacaacca
    42661 cagggattgg tttttgtaaa ggaagtatag aaatcagata ttttgtattt ggcaatatgt
    42721 atcatcagct attttagttt ataaatgaga aaaaagcgaa caagctagtc ttctgagtgt
    42781 cagaaaagta gtcttgttcg cttttattat gttatactct tcgaaaatct cttcaagcca
    42841 cgtcagtgtc gccttaccgt atatatgtta ctgacttcgt cagttctatc tacaacctca
    42901 aagcagtgct ttgagtagct tgcggctagc ttcctagttt gctttttgat ttttattgag
    42961 tgttagttac ttgatagctt cgaccaagtc ttgagcttgt ttttcaagtg agtttaggac
    43021 tgtttcttca agaaccaatt ttccgtctgc ccaggcagag tcattaacac gtgcagcagt
    43081 gaaatcacca acgccttgtg tacggataaa tggcaagagg tctttgtaga tagcgaaaag
    43141 ttgatcgtgc cctgcattgg ctacagatga tactgtgaca aacttgtctt gaagggcaga
    43201 aacgccacgt gtatcagaca agtcaagggc acgagatagc cagtcaagca agtttttcac
    43261 tgtaccaggg atagagaagt tgtagactgg agagaaaatc cagatagcat ccgcaacgag
    43321 aactgcttca cgagcagcag ctacagctgg atgtgttgga acttccaaat cttggctgaa
    43381 gagaggaagg gctgaataat caaggtagct aacttccgct ttaccagcaa gtgctttctc
    43441 agcttcgagc gccatttggt ggttgaaaga accttgacgt agtgatccga cgataaataa
    43501 tactttttta gacatgatgt gtctcctttt tcttaaaatt tcgagaactc tctcgttgtt
    43561 ataaaatata ttacaacaaa acaaaagaac ttgcaagaaa tttgctcaga gtttatttga
    43621 aaattgtaaa atttcggaaa ctctagtcat ttgtgactga aaaagtaaga actgtttcac
    43681 tttcaaaatc ggttttgttt gaagggagaa atagaattgg ttgctcaaag cacagctttg
    43741 aggttgcaga taaagctgac gtggtttgaa gagattttcg aagagtattc ttatattcac
    43801 ttgtaataaa gcttaataga tggtaaaata gacgagtgaa aaaaagacaa aacaaagcaa
    43861 aaaataatct actgtggcag tatggtctag ggatgacgat tttgtttgtg gttatcagtg
    43921 cttcctttct gtatatggtt tctcttagca tgaaacccta tcaaacagct aaaagtgaag
    43981 gagaaaaatt agctcagcag tatgcaggat tagagcaggc cgatcaggtt gatttataca
    44041 atggcttgga atcttattac agcgttcttg gtcgtaataa acagcaagaa gcacttgctg
    44101 ttctgattgg aaaagatgat cataagattt acgtttatca gctaaatcag ggtgtttcac
    44161 aagaaaaagc agaaacggtt tctaaggaaa agggagctgg cgaaattgac aagattatct
    44221 ttggtcgtta tcaagataag ccaatctggg aagtcaagtc aggatctgat ttttatctag
    44281 tagattttga aacaggagca ttggtcaaca aggagggcct atgaaattat ccaaccgtgt
    44341 tttagaaatg gaagaaagtg tgactttggc tgctggagcc cgtgccaaag cactgaaggc
    44401 tgagggcaga gatattttgt ctctaacctt gggtgagcca gatttcacta ctcccaaaaa
    44461 tatccaagat gccgccattg catcgattcg agatgggcgt gcttcttttt atacagtaac
    44521 ctcaggtctg ccagagctta aggcggcggt caatagctac tttgagcgct tttacggcta
    44581 ttctgtagcg tcaaatcaag tgacagtcgc tgcgggagcc aaatattctc tctatacctt
    44641 ctttatggct gtggtcaatc caggtgatga agtcatcatc ccaaccccat actgggttag
    44701 ctatggagat caggtcaaga tggcagaagg cgttcccgtc tttgtttcta ctaaggaaga
    44761 caatcacttt aaggtgaccg tagatcagtt agaagcagct cgcactgaca agaccaaggt
    44821 tttggtgctg aattcgccat ctaatcccac aggtatgatt tacacccgtg aggaactctt
    44881 ggcaattgga aactgggctg tagaaaatga tattctcatc ctagcagatg atatctatgg
    44941 ccgcttggtt tataatggtc atgagttcac accgatttct agcctatcgg aagcgattcg
    45001 caagcaaaca gtggtcatca atggtgtgtc taaaacctat gccatgactg gttggcggat
    45061 tggttatgcc gttggagaag cagacattat cgctgccatg tccaagattg caggtcaaac
    45121 aacttcgaat ccgtcagcag tagcccaata tgcagcagtt gaggctctat caggtgagca
    45181 agatactgta gaaagcatgc gtcaggcctt tgaggaacgt cttaatacta tctatcccct
    45241 ccttgcagag gtgccaggat ttgaagtggt caaaccgcaa ggggccttct atctcttccc
    45301 aaatgtcaaa aaggccatgg agatgaaagg atacacggat gtgacagact ttacaactgc
    45361 tatcttagaa gaagccgaag tggccttggt aacaggagct ggatttggag caccagaaaa
    45421 tgtccgcctc agctatgcga cagacctaga cacgcttaaa gaagcagtcg aacgcttgaa
    45481 agcatttatg ggtagtgaga atgattgatc attttgagat taaggtaaag gatttacaaa
    45541 tttcagaagg attttatagg agttttctcg ctcctttgga ctataaaatg gcttttaaga
    45601 ctagttctct aattagtttt ctatccccga acagccctca tcctggtggt gatttttggc
    45661 tgactcaggg aacacaagat cctgttcatt ttgctttttt agcagaaaat aaggaagaag
    45721 ttcaggcttg ttatgaggct ggcttagagg caggtgggcg agacaatggg gttcctggtt
    45781 atcgaagtga gcatccgatt tattatgctg cttttatgat tgacctggat gggaacaata
    45841 tagaggtggt ttgccataaa gaataaaaaa gaaaaggaaa aataatgaca aaacgtgtaa
    45901 cgattattga tgtaaaagac tatattggtc aagaagtgac gattggcgct tgggttgcca
    45961 acaaatcagg aaaagggaaa atcgctttct tacaattgcg tgatggaaca gccttctttc
    46021 aaggtgtggc ttttaaacca aactttgtcg aaaaatttgg tgaagaagtg ggacttgaga
    46081 agtttgatgt tatcaaacgc ttgagccaag aaacgtctgt ttatgtgaca ggtattgtca
    46141 aagaggacga acgttctaaa tttggctatg agttggacat cacagacatc gaagtgatcg
    46201 gtgaatctca agactaccca atcacaccaa aagaacacgg aacagacttt ttgatggata
    46261 accgtcactt gtggctacgc tctcgtaagc aagtagctgt gttgcaaatc cgtaacgcta
    46321 ttatctatgc aacttatgag ttctttgaca agaacggttt tatgaagttt gacagcccaa
    46381 ttctttcagg aaatgcggca gaagattcta cagaactctt tgaaactgac tacttcggaa
    46441 cgccagccta cttgagccaa tcaggtcaac tttacctaga agcaggggct atggctcttg
    46501 gtcgtgtctt tgactttggt ccagttttcc gtgctgaaaa atcaaaaaca cgccgtcact
    46561 tgactgagtt ctggatgatg gatgctgagt actcatactt gacacatgat gagtcgcttg
    46621 acttgcaaga agcttatgtg aaagctcttc tacaaggtgt tcttgaccgc gcgcctcaag
    46681 ccttggaaac cttggaacgt gatacagaac tcttgaaacg ctacattgca gagccattca
    46741 aacgtatcac ttacgatcaa gccattgacc tcttgcaaga gcatgaaaat gatgaagatg
    46801 ctgactacga gcatcttgag catggtgatg actttgggtc accacacgaa acttggattt
    46861 caaaccactt tggtgtgcca acatttgtca tgaactatcc agcagccatc aaggctttct
    46921 acatgaaacc agttcctgga aatccagagc gcgtgctttg tgcagacttg cttgctccag
    46981 aaggctatgg agaaattatc ggtgggtcta tgcgtgagga agattacgat gcccttgtcg
    47041 ctaagatgga tgaacttggc atggatcgta cagaatatga attctacctt gaccttcgta
    47101 aatacggtac agttccacac ggaggatttg gtatcggtat cgaacgtatg gtaaccttcg
    47161 cagcaggaac aaaacatatc cgtgaagcta ttccattccc acgtatgttg caccgtatca
    47221 aaccataaga acaggaaaac gcccatgtgg cgttttttcg aattctagtg tttttacttg
    47281 cgtaaaaaaa ttttttctag tataatagtt tattgtgagc gaacctcact taccccttgc
    47341 aaagtcttgg ggtcattaga ccaaaaggag gaacatatca atggctaaat acgaaattct
    47401 ttatatcatt cgtccaaaca ttgaagaaga agctaaaaac gctttggtag cacgttttga
    47461 ctctattttg actgacaacg gtgcaactgt tgttgaatca aaaacttggg aaaaacgtcg
    47521 tcttgcatac gaaatccaag atttccgtga aggactttac cacatcgtta acgttgaagc
    47581 aaatgacgat gcagctctta aagagtttga ccgtctttca aaaatcaacg ctgacattct
    47641 tcgtcacatg atcgtcaaaa ttgacgcgta agaaggtaaa ctatgattaa caatgttgta
    47701 cttgtagggc gtatgacacg tgacgctgag ttgcgttata ccccatcaaa tgtagcagtt
    47761 gcgactttta ctcttgcagt aaaccgtaca tttaagagtc aaaatggtga acgtgaggct
    47821 gattttatca atgtcgttat gtggcgccaa caggctgaaa atcttgctaa ctgggctaaa
    47881 aaaggctcac ttatcggggt gacaggtcgt atccagactc gtagttacga taaccagcaa
    47941 ggacaacgtg tctacgtgac agaggtcgtg gctgagaatt tccaaatgtt ggaaagccgt
    48001 agtgtgcgtg agggtcacac aggtggagct tactctgcac caactgcaaa ctattcagca
    48061 cctacaaatt cagtaccaga cttttcacgt aatgaaaatc catttggagc aacaaaccca
    48121 ttggatattt cagatgatga tttaccattc taatggacaa ctaaacttat aaaggagaaa
    48181 aaacatggct caacaacgtc gtggcggatt caaacgccgt aaaaaagttg attacatcgc
    48241 agcaaacaaa attgaatatg ttgattacaa agatactgag cttcttagcc gtttcgtttc
    48301 agaacgtggg aaaatccttc ctcgtcgtgt aacaggaact tcagctaaaa accaacgtaa
    48361 agtaacaaca gctatcaaac gcgctcgcgt aatggctttg atgcctttcg taaacgaaga
    48421 ttaaagaaaa gacccggttg ggtctctttt tcatgagctt gaaaacaaga aagcgaatta
    48481 agaccccaac gggtcttttt tcacaagctt tgaaatgaga gagcgagtta ggctcagtgg
    48541 cttccttttt acgagtttga aaacaagaga acacattaaa agcacgatgg agctttttca
    48601 taaatatgtc tcttttctca tccaagaaat taaaataaaa atgataaact ttttgaaaat
    48661 aggggatttg cctactttat gatataatgg aaagagttag attgaaagag gtagtgagat
    48721 ggacgcgaaa ttaagataca aggcaaagaa gatcaagatt gtcttttttg atattgatga
    48781 tacattgcgg aattcaaaga cagggtttat tccaactaca attcccactg tttttaaaca
    48841 gttgcgtgaa aaaggaattt taacaggaat cgcctctgga cgtggcattt ttggtgttgt
    48901 tccagagatt cgtgatctca agcctgactt ttttgtaact ttgaatgggg cttatatcga
    48961 agataaaaaa ggtcaggtca tttatcagca tcagattgaa aagtcagatg ttgaggagta
    49021 tatctcttgg gctaagcaag aaggaattga gtatggcttg gttgggagtc atgatgccaa
    49081 gttgtcgact cgcaccgata tgatgagtga agctatcaat ccaatttatc ccgacttaga
    49141 tgtagatccc gatttccatg aaaaagaaga tatctatcag atgtggactt ttgaagataa
    49201 gggagatgac ttgcacttgc ctgacagtct ctcagacaaa cttcgcatgg ttcgttggca
    49261 tcaacattcg tctgatattg tgccgatttc aggctccaaa gcgacggggg tggaaaaggt
    49321 tgtggaacac cttggcttga aaccagagaa ggtcatggtt tttggagatg gtctcaatga
    49381 cttggaactc tttgattatg ctggaatcag cgttgccatg ggaatttctc atgataaaat
    49441 caaagaaaaa gcagattata ttacaaaaac attagaagaa gatggcattt ttgatgcctt
    49501 agaagtattt ggtatggtag aaaaagaatt gcattttcca caagtagaca ttgaaacagt
    49561 agaaggtctt cttgcgacta ttaagaccaa tcacggagac ttacgtatca agcttttccc
    49621 tgaacatgct cctaaaacag tggctaactt tgtatctctt tcaaaagatg gctactatga
    49681 tggtgtcatt ttccaccgta ttatcaagga ctttatgatc caaggtggag acccaactgg
    49741 aactggtatg ggtggcgagt caatctacgg cgaatctttt gaggatgaat tctcagaaga
    49801 gctttacaat atccgtggtg ctctttccat ggcaaatgct ggtccaaata ccaacggcag
    49861 ccagttcttt atcgtgcaaa accaacacct accttattcg aagaaagaaa ttactcgtgg
    49921 tggttggcca gaaccgattg cagaaatcta tgccaatcaa ggtgggacac ctcacctaga
    49981 ccgccgtcac acggtttttg gtcagttagc tgatgaagca tcttacgctg tcttggatgc
    50041 cattgctgct gttgagacag gagctatgga caagccagtt gaagatgttg taattgaaac
    50101 tattgaaatc gaggactaag atgaaaatcg gtgataagct aaaggggcgt attacaggga
    50161 ttcagcccta cggtgccttt gttgagttag agacgggtga tacggggctg attcacattt
    50221 cagaaattcg gacaggattt attgaaaata ttcatgaaac cttgaaagtc gatgaagagg
    50281 ttcaagttca ggtactggat ttagatgaat ttacggggaa agccagtctt tctatccgca
    50341 ctttggagga agaaaagtac cagtttccta gacggagacg cttttcaagt gaccgcttta
    50401 actacggttt tgctcccttt cgacgaatgc taccaatctg gactggagaa gctctgcacc
    50461 atttaaaaaa gaagaagtag tttagagttt tatatttttt gtaatgttaa tataaattta
    50521 ttataatagg accatggaag aagaacaatt attaaaatca ggagagcgca ttaaccagct
    50581 cttttcgaca gatatcaaaa tcattcaaaa tagagaggtt tttagctatt cggtggatag
    50641 tgttctctta tcacgatttc cacgttttcc taagaagggg ttgattgtgg atttctgtgc
    50701 tgggaatgga gcagtggggc tttttgctag cactcgtact caagcacaga tattgtctgt
    50761 tgagattcag gagcgtttgg cggatatggc tgaacgctct gtccgtttga atggattaga
    50821 ggagcaaatg caggtcatct gcgatgattt gaaaaatatg cctgctcaca ttcaggggag
    50881 taaggtagat atgattttgt gtaatccacc ctatttcaag gtggatcctt attctaatct
    50941 gaacgagagt gaacattatc tcttggctcg acacgaaatc acgactaatt tggaagaaat
    51001 ctgtcgtagt gcccagagta ttctcaagtc taatgggcgt ttggccatgg ttcatcgtcc
    51061 tgatcgactt ctggatattt tggatacgtt aaaacgacat aatctagccc ctaagcgcct
    51121 gcagtttgtt tatccaaaaa gagaaaagga agccaatatg cttttgattg aggcgatcaa
    51181 ggatggctca acaagtggct ttaaggtctt acctcctttg attgtccaca atgatgatgg
    51241 ctcttatacg cccgaaatcg aagagattta ttatggatca taaggcttat atgtacgttc
    51301 tggagtgtcg tgatggatcc tactatatag gctatacgac tgatgtgaga agacgcctcg
    51361 ctatccacaa tagtgggaag ggagccaaat atacacgagc acgcttgcca gtcaaactta
    51421 tctatgctca aggttttgcc agtaaggaag aagccatgtc ggctgaagct cttctcaagc
    51481 gtaagaagag gccacagaag gaagaatttt tatctgaaaa tcaagataga aatttactca
    51541 gttattttga agaatcgtgg ggagtccttt gactcctctt acctttgtca aaaagcgaaa
    51601 aaaatgctac aataaagaaa ataaacaaaa tgaggtatta tcatgtccaa aattctagta
    51661 tttggtcacc aaaatccaga ctcagatgcc atcgggtcat ctgtagcttt tgcctacctt
    51721 gcaaaagaag cttacggttt ggatacggaa gctgttgccc ttggaactcc aaatgaagaa
    51781 acagcctttg tcttgaacta ttttggtgtg gaagcaccac gtgttatcac ttctgccaaa
    51841 gcagaggggg cagagcaagt tatcttgact gaccacaatg aattccaaca atctgtatca
    51901 gatatcgctg aagtagaagt ttacggtgtt gtagaccacc accgtgtggc taactttgaa
    51961 actgcaagcc cactttacat gcgtttggag ccagttggat cagcgtcttc aatcgtttac
    52021 cgtatgttca aagaacatgg tgtagctgtg cctaaagaga ttgcaggttt gatgctttca
    52081 ggtttgattt cagataccct tcttttgaaa tcaccaacaa cacacccaac agataaaatc
    52141 attgctcctg aattggctga attggctggt gtgaacttgg aagaatatgg tttggcaatg
    52201 ttgaaagctg gtaccaactt ggctagcaaa tctgctgaag aattgattga tatcgatgct
    52261 aagacttttg aactcaacgg aaataatgtc cgtgttgccc aagtgaacac agttgacatc
    52321 gctgaagttt tggaacgcca agcagaaatt gaagctgcaa tgcaagctgc aaacgaatca
    52381 aacggctact ctgactttgt cttgatgatt acagatatcg tcaactcaaa ctcagaaatc
    52441 ttggctcttg gtgccaatat ggacaaggtc gaagcggctt tcaacttcaa acttgaaaac
    52501 aatcatgcct tccttgctgg tgccgtttca cgtaagaaac aagtggtacc tcaattgact
    52561 gaaagcttta atgcgtaaga ttttgggtgt cagctcaaaa tcggaaagtc tagtttgcct
    52621 tatatcgaaa ggagtttcgg ctcctttttt ctaggagtga agtatgttag aaaatggcga
    52681 tttgattttt gtgagagatg ggtcagacat gggacaggcc atccagactt ccacaggtaa
    52741 ctatagccat gttgccattt atttggatgg gatgatttat catgctagtg gacaggctgg
    52801 tgttgtctgt caagaaccgg cagacttctt tgagtccaat catttgtacg acctctatgt
    52861 ttacccagaa atggatatcc agtcggtgaa ggaaagagct tgcagacatc ttggagcacc
    52921 ctacaatgct tctttctatc cagatgcagc tggtttctac tgctcccagt atatagcaga
    52981 aatcctacct atttttgaaa ctattcctat gaaatttgga gatggggaac aggagattag
    53041 tgatttttgg agggagtatt acatagaact aggtctgcct gttcctctga accaagctgg
    53101 gaccaatcct agtcagttgg cagcatcgcc tctgttacaa tgtaaagaaa ggaatcttca
    53161 tgattcagat ttttaatcca tctcgtttga cgagacagcc atttttggag aattgatccg
    53221 ctatctggac cagtatgagg atgtgattct acgggaaatt aaggctcaat ttccagatgt
    53281 tgcagttgat aaactcatgg aagagtatat aaaggcaagc ttgattctac gtgaaaataa
    53341 gcgctattac ctcaattttc ctacgcttga atcacttgat agtcttgaac tggatcaaga
    53401 gatttttgtc agagaagcta gtccggtcta tcaagccttg ttggagcaga gttttgagac
    53461 ggaattgcgc aatcaaatca atgcagctat tttagttgaa agacggactt tgcgcgcatt
    53521 aaaatgaccc tgtccaatta tttttacaag gtcaaacagc agtatccttt gacagaaaaa
    53581 cagcaggagc tctatgacat tttaggagat gttaatcctg agtatgcact caagtatatg
    53641 acggcttttt tgttgaaatt tctcaaaaaa gaccagctta tgcagaaatg ccgtgatatc
    53701 tttgtggaca gtttggttgt cttaggctat attgtgcaaa atgaagatag aaagtatgag
    53761 ttggctatcg attttgataa ggagagatta actttctact tagcgtgatt tcttgtttct
    53821 gagcacattg tttgactttc cttagtattc ggtataaact atatgtaacc ggtaacacat
    53881 atcggaataa actaaaggag acaatcatat gtcacttgaa aacaaattgg aacaagcaac
    53941 aggcgctgtc aaagaaggtt ttggtaaagt tactggagac agcaagacag aacttgaagg
    54001 agctgttgaa aaaacagttg ctaaggcaaa agacgttgta gaagacgcaa aaggtgctgt
    54061 agaaggtgcc gttgaaggtt tgaaaaacgt ttttactaaa taataggaaa aaatcaaggg
    54121 tttcattttc ccttgatttt ttctattctt ataaataatt ttctgcgacg gctgtatctc
    54181 ctgggtagga ttctttcttg ccctggatga tttggtaaca atcggctccc ttacccgcaa
    54241 taataactgc atctaattcg tgatttgtga tagccattgc cgccttgatg gcttcttggc
    54301 gatccgcaat cttttcaaca ggatgattga tgtagctact aatttcatct gcaatggcca
    54361 ttgggtcttc atagttaggg tcatcagcag tcagaaagac ttgaatctca gggtgttgat
    54421 tgaggaggag gccaaagtcc ttacgacgac tttctccctt gtttcctgtt gatcccagaa
    54481 ccagagcaat ctttccggtt tgatgagttt caaccacatt gatgagtttt ttcagactat
    54541 ccccattgtg ggcatagtcg atgaagacct tggctccatt tttctgagtg aggacttcca
    54601 tacgaccagg aacgcgggtt gcagcgatgc cttttttgat gtcctcaaga cttgctccga
    54661 gacggagaca agcaagtcca gcagcaactg cattttcttg gttgaagttg ccaatgagtt
    54721 ggatatcata atctccagcg agtttacccg tagctgaaaa gctaaaggct ttggaattct
    54781 cgatttggtt atcaaattgg ctaccataga aatcatggtc ttgatcttca acctgttctt
    54841 tcaagactga gaagtggtcc atgtcactgt taatgatgac tgctcggcta ttttccatca
    54901 agagacgctt gtggtagaaa tagtcttcaa agctagagtg ttcaatcggg ccgatatggt
    54961 caggagtgat gttaagaaag actcctacat caaaggtcag tccatagact cgatggacta
    55021 gataggcttg actggagact tccatgatga ggtgggtacg gtcattttgc acagcctgat
    55081 tcatcatgtc aaagaggtca atactctcag gggttgtcaa cgctgactta aaaaaagtct
    55141 cgccatcaag agttgtgttc atggtcgaca acatagcagg tctatgccct tgagataaga
    55201 tgttataggc gaaataggtt gctgttgtct tacccttagt accagtaaag gcaaggagtt
    55261 tgagtttctc ttgtggatta ccatagaact ccatggcaat caaactcatg gctttcttta
    55321 tatcgttcac aatgatgaca gggatatcga cttcgtagtc cttttcagct acataccaag
    55381 ctaaaccttg tgttatagca gaaagaaggt attctttttt aaaggcagcg ccttttgcaa
    55441 aaaaaagagt gtcttctgtt acttttcggc tgtcgtagct gatgctatca aaaataactt
    55501 tgctgtagtt gtagtggtaa tgaccttggt caataatttc gcgaaaaagg ccatctttct
    55561 ttaaaatatc taatacggtt tcaatcttaa tcatactttc tattgtaaac cgaaagtcgt
    55621 aaatttacaa gtaacaagga aaagtttata atggaagata aggagttttt cctagttatc
    55681 aaaattgaat gaggaatcta tgtcgcacga aaacaatcac cagcaggccc agatgttacg
    55741 ggggactgct tggctaacgg ctagtaactt tatcagtcgc ctactcgggg ctgtttacat
    55801 tatcccttgg tacatctgga tgggggctta tgcagctaag gcaaatggtc tctttaccat
    55861 gggttacaat atctatgctt ggttcttgtt ggtttcaaca gcggggattc cagttgcggt
    55921 ggccaagcaa gttgccaagt ataataccat gcgagaagaa gagcatagct ttgccctgat
    55981 tcggagcttc ttaggcttta tgacaggact aggtctggtt tttgctttag tcttgtatgt
    56041 ctttgctcct tggctagcag acttgtctgg cgtgggcaaa gacttgatcc caatcatgca
    56101 aagcttggct tggggagtct tgattttccc gtctatgagt gttatccgag gatttttcca
    56161 agggatgaat aacctcaaac cctatgctat gagccaaatt gctgagcagg tcattcgtgt
    56221 tatctggatg ctcctagcaa cctttatcat tatgaagctc ggttcaggag attatctagc
    56281 agccgttacc caatcaacct ttgctgcctt tgtcggtatg gtagccagtt ttgcagtctt
    56341 gatttatttc cttgcccaag aaggttcact caaaagagtc tttgaaacag gagataagat
    56401 taacagtaag cgtctcttgg ttgataccat taaggaagcc attcctttta tcctgacagg
    56461 gtctgccatc cagctcttcc agattttgga tcagctgacc tttatcaata gtatgagctg
    56521 gtttaccaac tacagcaatg aggacttggt tgtcatgttt tcttatttct cagccaatcc
    56581 taataaaatc acgatgattt tgatttctgt aggggtttcg attgggagtg ttggtttgcc
    56641 acttttgacg gaaaactatg tcaaggggga cttgaaagca gcttctcgtc tcgttcagga
    56701 cagtctcacc ctactcttta tgttcttgct accagcaacg gttggagtgg ttatggtagg
    56761 agaacctctt tatacggtct tctatggtaa gccagatagt ttggctctgg tcttatttgt
    56821 ctttgcagtt ttgcagtcta ttattttagg cttgtacatg gtcttgtctc caatgcttca
    56881 ggccatgttc cgcaaccgca aggccgttct ctattttatc tatggttcta ttgccaagct
    56941 agtcttgcaa ctacctacca tcgccctctt ccacagttat ggtcctttga tttcaacaac
    57001 cattgctctc atcattccta acgtcttgat gtatcgggat atttgtaaag taactggtgt
    57061 caagcgcaag gtgattttga agcgaaccat tttaatcagt ttgctgaccc tagtcatgtt
    57121 tctgttaata ggaaccatcc agtggctgtt aggatttttc ttccaaccaa gtggacgttt
    57181 gtggagcttc ttttatgtag ctcttgtcgg tgccatgggg ggtggacttt atatggttat
    57241 gagtctgcgt acctatttat tagataaggt aataggaaaa gcccaagcag atcgcctgcg
    57301 agcaaaattt aagctttcgt aaggtagcat ttataaataa aaggaataag ttgaacaatc
    57361 ttttaggaga acttgaaact tattcctttt ttagcgtcaa aatagctaaa attatctttc
    57421 aaaaatagaa aatgaggttt ttttgatttt ttggaaaaaa caattgacta aacaaaccca
    57481 gagttgtata ataaaacaaa tatttaaagc aggaggttct ggaaatgaaa aagtctaaga
    57541 gcaaatatct aaccttggca ggtcttgtcc tgggtacagg agttttattg agcgcgtgtg
    57601 gaaattctag cactgcatca aaaacctata actatgttta ttcaagtgat ccatctagtt
    57661 tgaactatct agcagaaaac cgcgcagcaa catccgatat tgttgcaaat ttggtagacg
    57721 ggttattaga aaatgaccaa tatgggaata ttattccatc attagcagag gattggactg
    57781 tttctcagga cggtttgacc tatacctaca aacttcgtaa ggatgccaag tggtttactt
    57841 ctgagggaga agaatatgcg cctgtaactg cccaggattt tgtgacaggt ttgcaatatg
    57901 cagctgataa aaaatcagaa gctttgtatc tagtgcagga ctctgttgct ggtttggatg
    57961 actatatcac tggtaaaaca agcgactttt caactgtcgg tgtcaaggca cttgatgacc
    58021 aaacggttca atatactttg gttaaaccag aactttactg gaattcaaaa acacttgcaa
    58081 cgatactttt tcctgttaat gcagatttcc tgaaatcaaa aggggatgat tttgggaagg
    58141 cggatccatc tagtattttg tacaatggac ctttcttgat gaaagcactt gtctcaaaat
    58201 ctgctattga atataagaaa aaccctaatt actgggatgc taagaatgtc tttgtagacg
    58261 atgtgaaatt gacctactat gatggtagcg accaagaatc actggaacgt aattttacag
    58321 ctggtgctta tactacggct cgtctttttc ctaacagctc cagctatgaa gggattaaag
    58381 aaaaatacaa aaacaatatc atatatagta tgcaaaattc aacttcatat ttctttaatt
    58441 ttaacctaga taggaagtct tacaattata cttctaaaac aagtgacatt gaaaagaaat
    58501 cgactcagga agcagttctc aataaaaact tccgtcaggc tatcaatttt gcttttgaca
    58561 gaacatctta tggggctcag tctgaaggga aagaaggtgc aacaaagatt ttgcgtaacc
    58621 tagtggttcc tccaaacttt gtcagtatca agggaaaaga ctttggtgaa gttgtagtct
    58681 ctaagatggt caactatggt aaggaatggc aaggtatcaa ctttgcggat ggtcaagacc
    58741 cttactacaa tcctgagaaa gccaaggcta agtttgcgga agctaagaaa gaactcgaag
    58801 caaagggtgt tcaattccca atccacttgg ataagactgt ggaagtaaca gataaagtag
    58861 gcatacaagg agttagttct atcaaacaat caattgaatc tgttttaggt tctgataatg
    58921 tagtgattga cattcagcaa ttaacatcag atgagtttga cagttcaggc tactttgctc
    58981 aaacagctgc tcagaaagac tatgatttat atcatggcgg ttggggacct gattatcaag
    59041 acccgtcaac ctatctcgat atttttaata ctaatagtgg aggagttcta caaaatcttg
    59101 gactagagcc tggagaagcc aatgacaagg ctaaggaagt tggactggat gtctatactc
    59161 aaatgttgga agaagctaat aaagagcaag atccagccaa acgttatgag aaatatgctg
    59221 atattcaagc ttggttgatt gatagttctt tagttcttcc aagtgtttcg cgtgggggaa
    59281 caccatcatt gagaagaacc gtaccatttg ctgctgccta tggtttaacc ggtacaaaag
    59341 ggattgaatc atataaatac ctcaaagtac aagataagat tgtcacaaca gacgaatatg
    59401 caaaagctag agaaaaatgg ttgaaagaaa aagaagaatc caataaaaaa gcccaagaag
    59461 aattggcaaa acatgtcaaa taaaatctaa ttgtagataa gtttgtgtaa gaagtctttg
    59521 tgcttaaaaa cgcataatat caggtatata aaatcctaga tgttatgcgt tttgttatag
    59581 gaagatttat tagattttat cctcaaattg agttattccc gactttatcc gttgaaatat
    59641 tataaggagt atttatgaaa ttaaaattat taagagtaga tactaaggtg attatgggga
    59701 gtttcttact tgttctgtct agtctacttg ctttgttgct tccccttatc ttaaagggtt
    59761 taatagatgg gagttctatt gaaaatatag gttccaaagt atttcaatcg tttttgattt
    59821 ttattggtca agccttgttt tcttctattg gttactatct gtttagtcaa tcgggtgaaa
    59881 aaaagatagc aaaaatcagg aaaaaagtga tagaggggtt gatttatgca gagaaatcct
    59941 tctttgataa gagccaaagt ggggagttga cttctgccat tgtcaatgac acgagtgtca
    60001 ttcgtgagtt tttaattacg actttcccaa atattattct gagtttagtt atggtacttg
    60061 gttccattgt agtcttattt agtcttgatt ggaatctttc tctactttta ttcatcactc
    60121 ttccttgtat gatgtttatt atcttgctcc tttccaatat cagtgaaaag tatagtcgtc
    60181 gtttacagga ggaaatcgga tttttaacag ggtaattgac tgaaaagatt caagaacatg
    60241 aattaattaa gactaaccaa gcagagaaaa gtgtacagga tgttttggat aattgtattg
    60301 aaagggtaca aaacaattca ctgaaatcag atagggttac ttcttttgag accccgtttg
    60361 ctctcttatt tatctttgcg actatagctg tgatgctaac ctatgggggt tatcgggtca
    60421 gcgcaggata tatatctgtg ggaaccttgg tttcgttttt gatttacctc tttcaattac
    60481 ttaatcctat tagtaatata gctaattttg taactgttta ttctaggagc aagggatctt
    60541 cagttgcact ggagaacttg cttgcagttc ctaaagaaaa atttgagtga ggaaaatcgg
    60601 tatcaggaca agggttgaat tt
//
LOCUS       DAVBOH010000008        59576 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOH010000008 DAVBOH010000000
VERSION     DAVBOH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.008"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..858
                     /locus_tag="VQ873_000487"
                     /pseudo
     CDS             1..858
                     /locus_tag="VQ873_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(975..1322)
                     /locus_tag="VQ873_000488"
     CDS             complement(975..1322)
                     /locus_tag="VQ873_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3106812.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1433..3208)
                     /gene="spxB"
                     /locus_tag="VQ873_000489"
     CDS             complement(1433..3208)
                     /gene="spxB"
                     /locus_tag="VQ873_000489"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3106813.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3415..5658)
                     /locus_tag="VQ873_000490"
     CDS             complement(3415..5658)
                     /locus_tag="VQ873_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3106814.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5668..6039)
                     /locus_tag="VQ873_000491"
     CDS             complement(5668..6039)
                     /locus_tag="VQ873_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3106815.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(6050..6445)
                     /locus_tag="VQ873_000492"
     CDS             complement(6050..6445)
                     /locus_tag="VQ873_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3106816.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6629..6727
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6811..7602
                     /gene="thiD"
                     /locus_tag="VQ873_000493"
     CDS             6811..7602
                     /gene="thiD"
                     /locus_tag="VQ873_000493"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3106817.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7811..8443)
                     /locus_tag="VQ873_000494"
     CDS             complement(7811..8443)
                     /locus_tag="VQ873_000494"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3106818.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8436..9239)
                     /locus_tag="VQ873_000495"
     CDS             complement(8436..9239)
                     /locus_tag="VQ873_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3106819.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9239..9763)
                     /gene="thiW"
                     /locus_tag="VQ873_000496"
     CDS             complement(9239..9763)
                     /gene="thiW"
                     /locus_tag="VQ873_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3106820.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9768..10460)
                     /gene="tenA"
                     /locus_tag="VQ873_000497"
     CDS             complement(9768..10460)
                     /gene="tenA"
                     /locus_tag="VQ873_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3106821.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10471..11121)
                     /locus_tag="VQ873_000498"
     CDS             complement(10471..11121)
                     /locus_tag="VQ873_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3106822.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11123..12508)
                     /locus_tag="VQ873_000499"
     CDS             complement(11123..12508)
                     /locus_tag="VQ873_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106823.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12509..13069)
                     /locus_tag="VQ873_000500"
     CDS             complement(12509..13069)
                     /locus_tag="VQ873_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3106824.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13331..13419)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13628..14257)
                     /locus_tag="VQ873_000501"
     CDS             complement(13628..14257)
                     /locus_tag="VQ873_000501"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3106825.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14259..15041)
                     /gene="thiM"
                     /locus_tag="VQ873_000502"
     CDS             complement(14259..15041)
                     /gene="thiM"
                     /locus_tag="VQ873_000502"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3106826.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(15452..15991)
                     /locus_tag="VQ873_000503"
     CDS             complement(15452..15991)
                     /locus_tag="VQ873_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3106827.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(16206..16294)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16548..17684)
                     /gene="lctO"
                     /locus_tag="VQ873_000504"
     CDS             complement(16548..17684)
                     /gene="lctO"
                     /locus_tag="VQ873_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3106828.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18310..19800)
                     /gene="lysS"
                     /locus_tag="VQ873_000505"
     CDS             complement(18310..19800)
                     /gene="lysS"
                     /locus_tag="VQ873_000505"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3106829.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19928..20074)
                     /locus_tag="VQ873_000506"
     CDS             complement(19928..20074)
                     /locus_tag="VQ873_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3106830.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            20301..20969
                     /locus_tag="VQ873_000507"
     CDS             20301..20969
                     /locus_tag="VQ873_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3106831.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20929..21309
                     /locus_tag="VQ873_000508"
     CDS             20929..21309
                     /locus_tag="VQ873_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3106832.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            21319..21606
                     /locus_tag="VQ873_000509"
     CDS             21319..21606
                     /locus_tag="VQ873_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3106833.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            21607..22375
                     /locus_tag="VQ873_000510"
                     /pseudo
     CDS             21607..22375
                     /locus_tag="VQ873_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22387..23253
                     /locus_tag="VQ873_000511"
     CDS             22387..23253
                     /locus_tag="VQ873_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3106834.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKVNFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(23340..23987)
                     /locus_tag="VQ873_000512"
     CDS             complement(23340..23987)
                     /locus_tag="VQ873_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106835.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23984..24682)
                     /locus_tag="VQ873_000513"
     CDS             complement(23984..24682)
                     /locus_tag="VQ873_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106836.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24692..25444)
                     /locus_tag="VQ873_000514"
     CDS             complement(24692..25444)
                     /locus_tag="VQ873_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106837.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(25444..26208)
                     /locus_tag="VQ873_000515"
     CDS             complement(25444..26208)
                     /locus_tag="VQ873_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106838.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26304..26707)
                     /locus_tag="VQ873_000516"
                     /pseudo
     CDS             complement(26304..26707)
                     /locus_tag="VQ873_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26887..27519)
                     /locus_tag="VQ873_000517"
     CDS             complement(26887..27519)
                     /locus_tag="VQ873_000517"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3106839.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(27553..28254)
                     /gene="pyrF"
                     /locus_tag="VQ873_000518"
     CDS             complement(27553..28254)
                     /gene="pyrF"
                     /locus_tag="VQ873_000518"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3106840.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(28487..29686)
                     /gene="divIB"
                     /locus_tag="VQ873_000519"
     CDS             complement(28487..29686)
                     /gene="divIB"
                     /locus_tag="VQ873_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3106841.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29696..30754)
                     /locus_tag="VQ873_000520"
     CDS             complement(29696..30754)
                     /locus_tag="VQ873_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3106842.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30756..32108)
                     /locus_tag="VQ873_000521"
     CDS             complement(30756..32108)
                     /locus_tag="VQ873_000521"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3106843.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(32212..32853)
                     /locus_tag="VQ873_000522"
     CDS             complement(32212..32853)
                     /locus_tag="VQ873_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106844.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32855..34875)
                     /locus_tag="VQ873_000523"
                     /pseudo
     CDS             complement(32855..34875)
                     /locus_tag="VQ873_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34946..35245)
                     /locus_tag="VQ873_000524"
     CDS             complement(34946..35245)
                     /locus_tag="VQ873_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3106845.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(35611..35865)
                     /locus_tag="VQ873_000525"
     CDS             complement(35611..35865)
                     /locus_tag="VQ873_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3106846.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35885..37726)
                     /gene="typA"
                     /locus_tag="VQ873_000526"
     CDS             complement(35885..37726)
                     /gene="typA"
                     /locus_tag="VQ873_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3106847.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37888..38613
                     /locus_tag="VQ873_000527"
     CDS             37888..38613
                     /locus_tag="VQ873_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3106848.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(38653..38880)
                     /locus_tag="VQ873_000528"
     CDS             complement(38653..38880)
                     /locus_tag="VQ873_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106849.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38969..39349)
                     /locus_tag="VQ873_000529"
     CDS             complement(38969..39349)
                     /locus_tag="VQ873_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3106850.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(39349..39618)
                     /locus_tag="VQ873_000530"
     CDS             complement(39349..39618)
                     /locus_tag="VQ873_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3106851.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39682..40590
                     /locus_tag="VQ873_000531"
     CDS             39682..40590
                     /locus_tag="VQ873_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3106852.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(40644..41399)
                     /locus_tag="VQ873_000532"
     CDS             complement(40644..41399)
                     /locus_tag="VQ873_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3106853.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(41420..42349)
                     /locus_tag="VQ873_000533"
     CDS             complement(41420..42349)
                     /locus_tag="VQ873_000533"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3106854.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(42364..42987)
                     /locus_tag="VQ873_000534"
     CDS             complement(42364..42987)
                     /locus_tag="VQ873_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3106855.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42980..44218)
                     /gene="hflX"
                     /locus_tag="VQ873_000535"
     CDS             complement(42980..44218)
                     /gene="hflX"
                     /locus_tag="VQ873_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3106856.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(44211..45095)
                     /gene="miaA"
                     /locus_tag="VQ873_000536"
     CDS             complement(44211..45095)
                     /gene="miaA"
                     /locus_tag="VQ873_000536"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3106857.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            45216..45386
                     /locus_tag="VQ873_000537"
     CDS             45216..45386
                     /locus_tag="VQ873_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3106858.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(45434..46273)
                     /locus_tag="VQ873_000538"
     CDS             complement(45434..46273)
                     /locus_tag="VQ873_000538"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3106859.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(46370..47329)
                     /locus_tag="VQ873_000539"
     CDS             complement(46370..47329)
                     /locus_tag="VQ873_000539"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3106860.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(47456..48213)
                     /locus_tag="VQ873_000540"
                     /pseudo
     CDS             complement(47456..48213)
                     /locus_tag="VQ873_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(48263..48880)
                     /locus_tag="VQ873_000541"
     CDS             complement(48263..48880)
                     /locus_tag="VQ873_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3106861.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48881..50602)
                     /gene="pabB"
                     /locus_tag="VQ873_000542"
     CDS             complement(48881..50602)
                     /gene="pabB"
                     /locus_tag="VQ873_000542"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3106862.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50663..56305)
                     /locus_tag="VQ873_000543"
     CDS             complement(50663..56305)
                     /locus_tag="VQ873_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3106863.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(56327..56890)
                     /locus_tag="VQ873_000544"
     CDS             complement(56327..56890)
                     /locus_tag="VQ873_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3106864.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(57006..58697)
                     /locus_tag="VQ873_000545"
     CDS             complement(57006..58697)
                     /locus_tag="VQ873_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3106865.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58694..59431)
                     /locus_tag="VQ873_000546"
     CDS             complement(58694..59431)
                     /locus_tag="VQ873_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106866.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17638 a        13057 c        10782 g        18099 t
ORIGIN      
        1 ggactcgact ctctccttca agaaacacgt ggtggtcgta accatgcata tatgacagtt
       61 gaggaagaga aagcctttct tgcccgccat ttgaaggcta cagaggcagg agaatttgtt
      121 acaattgatg ccttatttca ggcttataaa aaggagttag gtcattccta cacacgtgat
      181 gccttctatc aactgttgaa gcgccatggt tggcgaaata ttacgccacg tccagaacat
      241 cctaagaaag cagacgctca aaccattgtt gcgtctaaaa ataaaatctc aattcaagaa
      301 gacaagaaag cgttttaaat atagtagacg ttttcataag gttcgcttga tgtaccaaga
      361 tgaggctggt ttcggtagaa tcagtaaact gggatcttgt tggtctccaa taggagtagg
      421 tccacatgtc catagtcact atatacgaga atttcgctat tattatggag ctgttgatgc
      481 ctatacaggc gaatcatttt tcttaagagc tggtggatgt aatactgagt ggatgaacgt
      541 ctttttagaa gagctttcac aagcttatcc agatgattat tttttactcg ttatggacaa
      601 tgctatatgg cataaatcaa gtaccttaaa gattccgact aatattggct ttgcatttat
      661 tcctccatac acaccagaga tgaacccatt gaacaagtgt tgaaagagat tcgtaaacgt
      721 ggatttaaga ataaagcctt tcgaactttg gaagatgtca tgaatcaact tcaagatgtc
      781 atacaaggac tggagaagga ggtgataaag tccatcgtta atcggagatg gactagaatg
      841 ctttttgaaa gcagatgagt attatatgca atttctttat ataaaaagac cggattgctc
      901 cgatctttca atagttcata ttctcaattt ctattttaaa aatagctaag gttaacgtca
      961 aatgactacg cgacctattt catacgataa aaatcaagca ctagaccagc aggtccttga
     1021 actaataagg actctgttcc ccaatcggtt acagttggtc cgtgtaaaac ctttatacca
     1081 agctcgttca accgtttgta gttctggtct acatcctcaa cctcgatatg aataatgatt
     1141 cctgactgaa agttttccaa aggaaccaaa tgattttgtg acaacataag gcagtgacta
     1201 ccaatcgtaa actgagcaaa accatcatca gcataatctg cctttttatc caagatatgc
     1261 tccaagtcag cacagacttg gggaacattt gaaacgataa tatctaattg atttaaattc
     1321 atttactctc ctccataaaa agaccggatt gctccgatct tttaaagttc tgctctatga
     1381 aaatcaaaga ataaagtcta caagtttcat atttgatttt cggcgagagg aattatttaa
     1441 ttgcgcgtga ttgcaatcct tcttcttcca agaagagacg gaatggtacg agttcttctg
     1501 cttcgtattt ttccttgaag gctttgatag cttcttctga gtgaagtttt ggatccaatt
     1561 caagtacttc tactggaagt ggacggtgtt gagtgatgcg agcatcgatg acaacagttt
     1621 taccttcttt gttcaattta acagcttctg caacaactgc atcgatgtct tcgatacggt
     1681 caactgtgaa tccaacagct ccttgagctt ccgcaatttt agcgtagtca gcgtttgtga
     1741 agtctacacc aaacaagtgt ttgtttgtat cttcgtattt gttcttgatg aagccgtact
     1801 cagcatttga gaagacaagg ttgataactg gaaggtcgta ttgaacgttt gtgataacgt
     1861 ctgggtagca catgttgaat gctccgtcac ccatgatgtt ccatacttgg cgatctggat
     1921 tgtctttctt agcagcgata ccaccaggaa gggcaatacc cattgtcgca aagagtggag
     1981 atgtacgcca catgttctta ggtgtcatgt gaaggtgacg agtagatgtt tgagtagtgt
     2041 tacctacgtc gattgagtag atagcgtctt gatcagcatg tttgttgatt gcattgtaaa
     2101 cttgatacaa ttgcaattca ccctcagttt taccttcgag tttgttcatg taatcacgcc
     2161 agttttgatt gttcttaacg tttgcacgcc accatggagt tgattcaact gggtttactt
     2221 tgtcaaggat agctttagct gcttgaccag catcaccaag gattgaagcg tcaagggcat
     2281 gacgtttacc aagtttgtaa gggtcgatat cgacttggat gaatttttca gtgttcttga
     2341 atgcttcgta aacttcagcg aatgggaagt ttgaaccaag gaaaagaact gtgtctgctt
     2401 caaagaccac ttcgttggct ggtttccaac caacacggta agcagaacct gtcaaacctt
     2461 catagttcca ttcgaaagct tcaaagtttt taccagttgt gatgattggt gctttgattt
     2521 tacgtgacaa ttcagtaatc acttcaccag ctttaacacc accaaatcca gcatagataa
     2581 ctgggcgttc agcattgttc aagatttcaa cagctttgtc gatttcaact tcgttcaaag
     2641 caggagcgat gaatgagcgt tcgtatgaac ctgaaccgta gtatgagttt tcatcgattt
     2701 cttggaaacc gaagtttact ggaatttcaa caacagctgg acctttttta gaaactgcag
     2761 cacggcaggc ttcgtcaatt acttttggca attgctcagc gtaagctaca cgtttgttgt
     2821 aaacagcgat accgttgtac attgggtttt ggttaagctc ttggaaagca tccatgttca
     2881 attcgttaac tggacgtgat ccaaggatcg ctaggaatgg agtgttatcc atagctgcat
     2941 cgtaaacacc gttaatcaag tgagtcgcac ctggaccacc tgaaccaact gcaaccccga
     3001 ttgagccgcc gaatttagct tgcataaccg ctgcaagagc acctgtctct tcgtggcgaa
     3061 cttgtaagaa acggatatct ttgtcttcag ccaaagcatc catcaatgag ctgagtgttc
     3121 ctgatgggat accgtagatt gtatctacgc cccatgtttt caatacgtta agcattgctg
     3181 cagatgcagt aattttccct tgagtcataa tgataactct ccttcaattt ttttaaactt
     3241 ggagaatacg attacataga attggaaacg ttctccaaat ttttactatt ccactgtatc
     3301 atatttatgc tgacttttct aaaaatctgc tcaaaactct ctattctcta ttctaataca
     3361 gttttgaaag tgttgtcatt tctgttttat aacaaagaaa tctagtcatt acttttagtc
     3421 tattttacta aaatttaaca gaagggaact ggtcagaaca gatacagaac taaaggccat
     3481 ggctagacct gccaattctg ggttgagagc cagtccaaca cctgaaaaga ctcctgctgc
     3541 aatcggaatt ccgacaacat tgtagataaa agcccagaaa agattgagta gaattcgatg
     3601 aaaggttttc ttactcatat caaaggcacg aaccactcct aaaagattat tggttgtcaa
     3661 caccaaatct gctgactcga tggcgatatc tgttccagct cccatagcaa tccccacatc
     3721 tgctacacta agggcaggag cgtcattgat accgtcccca acaaaggcta ctttccctga
     3781 ctgttgcagt ttatggattt catgggcttt ttcttctggc aagacgcctg caatgacctc
     3841 ttcaattccg atttgatctg caatagcacg cgccacacca gcattgtctc ctgtcagcat
     3901 gactgttcgg agaccacgtt tttttagctg actgatgact agcttagcat tttccttagg
     3961 aatatcttgc aaagcaagca agcctttgat ttcattgtca acagctaaga acacaactgt
     4021 cttagcttct ttttctagtt cttctagttt atcttgataa gtattagaaa tatccatgcc
     4081 atccagcatt ttagcatttc caagtaaaac ttgttttcca ttgattcgcc ctgaaacacc
     4141 tttcccgtgc aaggcctgaa aattttcaac agtttgaaac tcaagtccag cttcactcgc
     4201 tcgcttaacg atagcctcag ccagtgggtg ttgagaagca tcttccaagg aggctgccaa
     4261 tccaaacact tctacttcgt cgccgatgat atctgttacc acaggtttcc cttccgtcaa
     4321 agtcccggtc ttatcaaaga caagagtttg aactttctgg atttcctgta agacagttcc
     4381 atttttgagg agaaccccca tcttggcact acgtcctgtc cccaccataa gggctgtcgg
     4441 tgttgcaagt cccaaggcac aaggacaggc gataatcaaa accgccactc cgtagagaag
     4501 agaggacaca aagctagctc caagcacgac cacactatcc ctgagcaaga cgaaccaaac
     4561 ccaaaaggtc atgattccta aaatgacaac tactgggaca aaaatccctg aaatcttatc
     4621 cgtcaagtcc tgaatcggcg cacgacttgt ctgagctttc ttcacaaaat ccacaatctg
     4681 agccaaaaca gtctctgagc caactttttc tgctctaaag acaagcgttc cactatgatt
     4741 gatggttgag ccaatgacag tatctccaac tgtcttgtcc acaggcagac tctcacctgt
     4801 caccatggat tcgtcaatac tagagacacc ttctactacg acaccatcaa cagcaatctt
     4861 ttcaccggga cgcactcgaa tcaggtcgcc taccttgact tgttccaaag gaacttggac
     4921 ataactatca tcactcaaga cttctgcggt tttagcttgc aagtccagta atttctccac
     4981 agcttgggac gtattttttc tcattttttc ctcaaaaact gctcccaaaa gaacgaaaaa
     5041 gaggataaat ccagcacttt cgaagtaaac agggagacca gcaaagagag caactaggct
     5101 atagaaataa gccactagag ttcccagcgc aaccaaggta tccatgttgg cattgtgctt
     5161 tttaaaactg gcccaagcac tctggatata tggcttacct gcaactaaca taataggcgt
     5221 tgttgctaga aaggttcccc aatgcatgac ttgatgacta atgctacctg tcaacatccc
     5281 aatcatgaga atcacaagag gcacagtaaa gatactagta atccaaaaac gttgcaggag
     5341 agatagagat tttcgagtct tctcaacgac tatatagctt cccttttgca tcttcatgcc
     5401 acaagaaaat tcatgtcgcc ctaattcttg aggtgtaaaa cgaatgactt tctcctcatc
     5461 tacgccgatt ggttccaaga taccttcttc ttcaaacaga atttccttat aacagtttga
     5521 aggagtagca cgatgaaagg taatctcagc tggaattccc ttttgaagct ggatatgggc
     5581 tggatgatag cctttttcag ctcggatacg gattttttga atgccatttt ctaagcttgc
     5641 tttcacaatt tctgtcatag tctccaccta ctctacaatc atcttgccgt gcatcatgtt
     5701 cataccacaa gcaaagccaa actctccaac ctgctcaggc gtgatttcca ctacatactc
     5761 ttcccccatt ggcaggttcg catgtacacc aaaatctgga aaaacaattt gatccagaca
     5821 tggtgaagga tccttgcggt caaagacaat gcgtgctggc actgatttct tgaggacaat
     5881 caactcagga gtatagcctc ccatgacttc cactcgaatc tcttggtatc cgtttttttg
     5941 ctgggctttt tgtccagatt tttcaggctt tttgaaaaac caaaacaaga taaacgcgat
     6001 aagggcaata caaataatgg ttacaatact atttaacatg gcgtctcctt tacatacaat
     6061 tacatcttac ttctgttaca gcacttgatt tcttctctga aatcacagct tccaagtctt
     6121 ccaagtcagt ctgagtaaat tcacattcta caatcaagtc agccaacaaa ttcctaatcc
     6181 tacgggaaca aaccttgtct ttgatatctt ggacaagtaa atcccgactt tggtctagag
     6241 ttaaaagcgc tgaataaaca aaggacttgc cttctttttt ccgagtcaga cactctttct
     6301 caaccaaacg agccaaaaga gtttgaatgg tcgacttgga ccagtcgaac cgctctgcca
     6361 aaaccctaat caaatctgta ctggtctgct ccccctgcat ccaaataatc ttcatgacct
     6421 gccattctgc atctgaaatc tgcattacca tacctccaaa atctacattt gtcaattaca
     6481 ctcatcagta tactcttaaa atctacattt gtcaattata gaaataatat tttcttcgaa
     6541 aaatagaatt ttaatcattt gaaaaacgat ttgcagtcaa atattactat ataaacaata
     6601 aaaatatgct atactaaaga aaaaagaaaa caaccactag gggtgcgtaa agctgagatt
     6661 aacgactgtt agatccctct gactcaatct aggtaatgct agctgatgga agtggaaatg
     6721 ataatgggga ctagcagtct tctattgcct ttctaaaaca gactagcttg ttcttaagaa
     6781 tacaaacttc agttggttgg gaggttttag atgacttatt tacccgttgc tttgaccatt
     6841 gcagggactg accctagtgg tggtgctggc attatggcag atttaaagtc attccaagcg
     6901 agagatgtct atggaatggc tgttgtaacc agtcttgtcg ctcaaaatac cagaggtgtt
     6961 cagctaatcg agcacgtttc tcctcaaatg ttgaaagccc aattggagag tgtcttttct
     7021 gatattccac ctcaggctgt aaaaactgga atgttggcta ctactgaaat catggaaatc
     7081 atccaaccct atcttaaaaa actggattgt ccctatgtcc ttgatcctgt tatggttgct
     7141 acaagtggag atgccttgat tgactcaagt gctagagact atctcaaaac aaacttacta
     7201 cctctagcaa ctattattac gccaaatctt cctgaagcag aagagattgt tggtttttca
     7261 atccatgacc ccgaaggcat gcagcgtgct ggtcgcctga ttttaaaaga atttggtcct
     7321 cagtctgtgg ttatcaaagg cggacatctc aaaggtggtg ctaaagattt cctctttacc
     7381 aagaatgaac aatttgtctg ggaaagccca cgaattcaaa cctgtcacac ccatggtact
     7441 ggatgtacct ttgctgcagt gattactgct gaactagcca agggcaagag tctttaccag
     7501 gcagttgata aggccaaggc ctttatcaca aaagctattc aagatgcccc tcaactcggt
     7561 catggttctg gtccagtcaa ccatacaact tttaaagatt aagaaaaaaa ctctctagtt
     7621 cccactttaa gggaattaga gagtttttat actcttcgaa aatctcttca aactacgtca
     7681 gcttccatct gcaacctcaa aacactgttt tgagctgact tcgtcagtct tatctaaaac
     7741 ctcaaggcag tactttgagc aacctgcgac tagctttcta gtttactctt tgattttcat
     7801 tgagtattaa ttaggaaaga atgtcatgca actttgttaa aaaggcttgc gtttttgcct
     7861 caatatcttc tgcttgcatc aaatcacgta caacagctac accagctatg ccagtgccca
     7921 taagctgatc aatattctcc gaagtcaagc ctccaatagc aactactgga atggcaaccg
     7981 tttggcaaat tgttttcaag gtcgatatca gagtaatggg cgcattttcc ttggtggtgg
     8041 ttgggaaaat ggctcctgta cccaagtaat ctgcacctga tttctccgct tccagagctc
     8101 ttttaaccgt tttagcggtg acaccgagga ttttttcagg acccaagact ttgcgagcta
     8161 ccgaaactgg taattcatca tctccgatat gcagacctgc tgcatcaacc gcaagacaaa
     8221 catccaaccg atcatcgatt atcaagggga cctgataggc atctgttatt tccttgactt
     8281 gttttgccag ttgataatat tgattggttg tgagattttt ttctcgcaat tggactatgg
     8341 taacccctga acggcaggcc gtctcaactt ttgcaagaaa gctttccacg gaatcttgat
     8401 agcgattggt taccagatat agtctaagtg cttctctatt cataaacctc tcctttgatg
     8461 gtatctagcc aattttcatc tcttcttagg agcgaaagct gattgagtac ttggtaacga
     8521 aattcttcca atcccattcc ttgaacaact attttctcag cagcgatatt gagataagag
     8581 actgctaagc aagaagcttc aaaaccagtc tttccttggc tgagaaaaac ggctgttaag
     8641 gctccaacca agtctcctgt ccctgttatc cagtctaatt cagtacagcc attctccagt
     8701 acagcaactt gattctccga aacaataagg tccttggggc cagtaactaa gaaagacata
     8761 ccaggatagg tctgacacca gtctttcaag acttgaagca aatcctccgt ttcttgatct
     8821 ttagcactcg catcgacccc aacgccgtgg tgctttaatc caacaagact tcgaatttct
     8881 gacatgtttc ctttaaggac cgtaggtcta tagtctaaaa ggtctttaac taagctctta
     8941 cgaatggatg aagtcgttac gccaaccgca tctactacca tcgggagaga agattggttt
     9001 gcatacgaag ctgccatgcg gattgctttt tccttctcag ctgacaaatg ccccaaattg
     9061 atgaagagag cctgactttg cttagtaaaa tcaagaactt cacggggatc atctgccatg
     9121 acaggtttgc atcccagagc caaaatccca tttgccagca tctcacaaga aatctcattg
     9181 gtcatacagt gaatgaggga actagagcct ataggaaaag gatttgtcaa tgcctgcatc
     9241 attctatcct ttcagcaaag aaatatcctt gcactttttt aaagaattcc tgcttgatta
     9301 aaaatctaaa tgcaataaag gaaatcgctg taccaatcaa ggttgctccg aaaaatcgag
     9361 gagtgtagat aaaccaacta agcttagcag ccgatcctgt aaagagcacc ataacaggat
     9421 aggaaacaat agaaccaata atacctgttc ccacaatttc tcccaaggca gaaaagtaaa
     9481 attttcgacc gtacttataa aagagacctg ctagaagggc tccaaaagtc gctcctgtga
     9541 gagctaaagg cggaatccct tgagtcgtca tacggataaa ggctgtcact gtagccatag
     9601 ccaaggcata aacaggtccc atcatgattc ccgctagaat attgactaca ctggacatcg
     9661 gtgccattcc ctcaatccga aagataggtg taaggactac atcaagggca atcatcatag
     9721 ataaaatggt caatttgtga acttgtagtt ggtgctttct catgtttcta ttcttctcct
     9781 ttttctaaag actgtaaatc gctcttccat gtctggtgtt ggtaagccat ctcccaaaac
     9841 ttagcttcca tatgaacact gatgtggaag gcatctagca ttttttgctt atctgtctca
     9901 tcactttctc gataaagctg attgaccagt gctccctcct ctctgatctg ttgctctaac
     9961 tcatccgtaa tataagtttc aatccattgt tgatagagag gatttggtga tggtttaaga
    10021 ttaagtgatt tgcctatatc atggtataac caaggacaag gaagcaagct tgcaaaagct
    10081 atggctaagt tcggttctgc aaattgccta taaatatgag aaatgtaatg ataacaggtt
    10141 ggagcgattg gatgttgctc catttcctgg tcgttgattt ccaattcctt gaaaaattgt
    10201 tggcgaataa ataactcacc ctccactaaa ccctgagcat tttgtttcaa gagtcttttc
    10261 atctcttggt ttgaagtctt atcagccaaa agatgataga tttctgagaa agccttcaga
    10321 tagtaggcat cctgaatcag gtaatagcgg aaaatggcag gttctaaatt cccctcttgt
    10381 aattgtaaaa taaagggatg atgaaaggaa gcctgccaag ctttcttgga taattccatc
    10441 gcaatatctg taaattccat aataactcct ttataaaaat agactggttt gaagcaataa
    10501 aaagaaaagc aggtagatta attttgtttt tttaggaata taaaaagtcc gatagctatt
    10561 cttcaactgt gcatgttcgt catatccgtg agcagataga gctctcaggt aaagatggcg
    10621 ccacctaaag actgtcatca gaaccttact gtaaatcaag ggcgaccaaa aatgtagttt
    10681 ttgaccacgt aataggcaag cttctttgag ggacttgatt tcttgctgaa tgagaggaaa
    10741 agaattgaat accacaatca aggcatagga ccaagagcgt gatagcccct tttgagccaa
    10801 gtacaagaga agctctttta gtgaaataga ggaaacaaag acaaggccga tacaaactgt
    10861 cacaaaggcc ctcgttccaa gcatgactgc ctgtgaagca tctccgtgta actgaactgc
    10921 ccagtagttg gcaaaagatg gtaaaatggc aagtatgatc atccaagcta acattttaaa
    10981 tcgacggtaa tagagcataa agagaataca aaatgcgact accgaaagat tcagagcaat
    11041 cgaaggaatg aaagatgttt ccaaggataa aatcagcaag aagagactga taatcggtgt
    11101 ctgggttgct actttgacca tactatctca cctccccttg ggtattgcta ctctgagatg
    11161 taagtggttt ggtaatggtc acttctttca catgccgaag accctgacta gtcatctcaa
    11221 tccaataatc aaccacagaa atcaaagggt ctaaacgatg actaatgagc agaaaacttc
    11281 ttccttgatt cctctcctcc acaatccact tgcaaaaata atggcaggct ctatcatcca
    11341 aacctgcaaa aggttcatct agcaagatca cggaagcctt actggtcaag atggtcagga
    11401 gctgaagaat tttttgctga ccaccactta attgataggg actcttatcg actgcctgct
    11461 ccaaatcaaa atatcgtaaa gcttgaaaaa tccgctgatt tctttcagaa tcaggtccat
    11521 ctaattgaag ctcctctcgc agactgactc ggataaactg cttctcagct tcctgaacaa
    11581 cacccgtcag atcacggtac aaactctttt tctttttcag gactgtcccc ttccatgcaa
    11641 tgcgcccctt atacttttga aattgaagaa tagaccgaaa gagggttgat ttcccgacac
    11701 cattgtcacc caggatacag gaaatccctt gatagaatgt gaaatcagca attgaaaaga
    11761 gggggcgatt accaagctca ccagtcacac ggttcatatg gaataattcc gggctagaag
    11821 caacttcctt tgaagcaacc tgtgtcatct cataggaagg gatttgattt atttccctta
    11881 gttttccgtc tcttagctca accatatggt cgatataggc tttatagtca gataaatcat
    11941 ggtcgcacaa aataactgtc ttcccatcaa gagccaactc ttttagaatc tccaatatct
    12001 cgattctgct cttgcggtca atggaagcga agggctcatc caagagatat accctaggat
    12061 tcatggcaaa gaggacagcc agcgctgctt tttgcttttc cccacctgat aggtgatgaa
    12121 tgggacggtg taagattgcc tcgcaacgac attgctggac aacctctgct attttagaat
    12181 caatttcctg aaggtgatag ccgatattct ccaaggtgaa aatcaactcc tcaaacaagt
    12241 tctccatggt aaattgatga ttgggatttt gcaagagaat gccaaccttc tggacacgtg
    12301 cgatgataga aagctgactg acctcgctcc catctatcag gacttgacca ctatagggaa
    12361 gagaactgac ttgggcaatc atttgaaaga ggctggattt tcctgaacca ctgctcccaa
    12421 ctaacaaggt aaaggcttgc gcatgaaaag taaaatcaaa cggctcagag aagattgggg
    12481 actgaatcgc tcgtagttcc agacccatct atgcttttcc tccagttgca aactgatgat
    12541 agagtttgac aatggcacga accaagatgg tacagaagaa ataaacagaa ataaaacgta
    12601 ccacaagcaa ggaaaggaca aacggaaggg aaaaggcgta gtaacctaac ttaatgtatt
    12661 catagacaaa gctaacaagc gtaatcccaa tactattagc agttagagag agccaacttt
    12721 catagcgatt cttagttacg ataaaaccaa attcacttcc caaaccttga accaagccag
    12781 acaaaagagc tcctagacca aattggctac cataaaggac ttcagcaagc gcagctagca
    12841 cttctccaat cgttgcactt ccgactctcg gaacaaagat ggcagcaatg ggcgcagcca
    12901 tacaccagag accgaagagg atttcattgg caaaggcctg caaaccaaga ggtgttaaga
    12961 gtagactgag aatattatac acatatcctg aaccaacgaa aaccccacca aaaaagatag
    13021 acaagaaagc aagcaagata acatctttta actgccattt tttcaacata aaaaactcct
    13081 ttttttaaag aaaagtgggg cactcaagaa gaccgaccta aatactttgt atagcagact
    13141 gaatttagaa cagtacacaa gaacactaaa atatttctag aaattaattt gaattttcta
    13201 attgatttgt tcgcatctta tttcaatcta ctatatcatc ttcatccagt ttcgtaaaag
    13261 aaaaaactct aattacagat acgaattaga gttcagctta caagattaga cagttctttt
    13321 cgacatacga aaaaaacatt tcacatttcc cttcgccagt cttaactgta tcaggttcaa
    13381 tgggtatcat ctcagcctaa agcaccccaa atgcctttat tatttaatta tgtgattatt
    13441 ataacacaca ttttatacta gttcaagaaa ttgaactgga aatacagcct tgcactcaca
    13501 aagacagcag atctttcttt tgcaaaaaac aaatgacctg tttgatgaat tagctattca
    13561 agctgaatct agacatagct ttttaaaaaa ggaaaatcct acttacttag aatccaagga
    13621 tagatatcta ttgttcactc atttcccgaa cagttttttc tatatttttt gcatacgata
    13681 ttgccgaaat gattgaaacg ccgtcaacat tggtctttat aatgtcttta atatgtttcg
    13741 tctgtatccc accaattgca actaaaggca tttgtggcaa tagttttctc atcaattcaa
    13801 gaccttcata acctatagca ccaccagcat catcctttga ctgggtatca aatacaggac
    13861 caacaccaac ataatctaca tattcaactt ttgattgttg aaattcttcc tcgtttttta
    13921 tagaaagacc aattatttta tctggcatca attttctaat ttcatcaaca ccaatatcat
    13981 cttgacctac atgtacgcca tcagcgtcaa tttccattgc taaatctata tcgtcattaa
    14041 cgataaatgg aacattgtat tttttacaaa gttctttaat ttggatagct agctcaagtt
    14101 tttctaagcc ttctaaagca ccctcacctt tttctcgaaa ttgaaataag gttataccac
    14161 cttttaaggc ttcctcaacg actgtatata gattttttcc ttggcaagta gtcgttccac
    14221 aaataaaata tagttttagt aattctttat gaaacatctt acttcactct tttgaatttc
    14281 ttgacatctt catctgtaat ttcatataag gcatttataa attcaacttt aaatgttcca
    14341 ggaagatgtc catttggacg tttttccgcc atttctccag cgatattgta aaccaacatt
    14401 gctgtttcta atgatttcaa ttcttgacct ttttcaagtc cgataaagct tgctactaca
    14461 gctcctaata agcatcctgt cccaatgact ttcggcatca tagcactacc attatgaatc
    14521 gttaccactt ctccattaac agcaatggca tccacttcac ctgttactac tattggaata
    14581 ttgaacttct catttgctgc tagagcaatt tcgtcaatat tatctacgcc cgcactatct
    14641 actcctttag atgccacatc tattcctact aaagaggcaa tctctccagc attcccccta
    14701 atcgcagcta gtttgtaatt gttgattaaa tcatctgcta ctttttttct atattctcct
    14761 gctccacagg ctacaggatc taaaactgct gggacattat atttctctgc aattttcaga
    14821 gcagcttggt ataatttcca attttcatct gtcaatgttc ctatgtttat taataaacca
    14881 ccagcatact ttaataagtc ctctaaatct gctggaaact cactcatggc tggtgaggcg
    14941 cccagtgcta ctaatccatt tgctgtgaaa ttttttacta catcattggt gatgcaaatg
    15001 accaaaggtg ctttttcttt taataatttt aaacttgtca tattgaaatc cttccttttc
    15061 actttatacg atctactaat ttcgatttat ctttagttga gaattttttt catttacatt
    15121 gaatgattta tactcaatga aaatcaaaga gcaaactagg aggctaaccg caggttgctc
    15181 aaaacactgc tttgagcctg tagataagac tgacgaagtc agctcaaaac actgttttga
    15241 ggttgtggat agaactgacg tggtttgaag agattttcga agagtcttac ctcatcaaat
    15301 ttgtaaatat catgagcctt ctctagacat cgtaaccaat atcaaaaaaa gctaattcta
    15361 aagcgactgc ttgattccag cgttgctgaa gttctgtcaa atcttctcga tttttaccga
    15421 cacgattgag ttcatcaacc agaaattgaa ctcactctgc aaagaaagga cctctgtgga
    15481 gattgatcca ttccgaatga atatagactt caggtagagc caaatcttta gaaccccagt
    15541 ctaaatagag accttctgca atgaccagca taaccaaaag atgggcatag tctgatgaag
    15601 ccactgccca atacattaga tcctgaaagg cttttgttac agggtgcaaa gtcacttcta
    15661 gatagttatt ctctgctact tttaactctt taaaagcctt ttggaaataa ccatcttcat
    15721 ctgcttcaag aaagcctagt tgcttggcaa aacgaagctt ggattcaagt ttatctgcgt
    15781 gagctacgca ggcacccagc atggataaga aggcatcaaa gaagtgataa tcttgaatca
    15841 gatagtcctt taagacctta ttctcaattg tccccgcaaa aagttcctta acaaaacgat
    15901 gattgattgc agcctgccaa tccttctgac tgctttttaa taattctcca acagtcaaac
    15961 ctggctgaaa tgcatagtct tgtgtttcca tatttacttc tcctctcttt acttgttagt
    16021 aattaataaa acagcaagaa atatcaagca aaatcgtaat tccacttgat ccttttaaag
    16081 cacatcgaga gcatttacag agagctaact aaacaagcct atccagttta tataaacaaa
    16141 aaactccaat tacaatcaag aattagagtt gacttacaag attagaccgt tcatttcacc
    16201 atacgaaaaa actgttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt
    16261 attatctcag cctaaagcac cccaaatgtc tctattattt aattactgaa ccagtatagc
    16321 aaaaaatgaa agccctagca agatatttga ccgaaaaata tctttatata caatatattg
    16381 aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt aactgtcctg
    16441 attgatttgt cctattctta tttcatttta ctatagtttt cgatagcgat ttattcttcc
    16501 aatacacgaa gaaaaacctc cacattcagt gaaggcaatc tgttttatca atacaatttt
    16561 aagtcacgag ggtcaactgg gaaggttggg ttgtatggat tgtgacggag cttaaagtgt
    16621 ttgacatctt caatggtctg agctccagac aattgcataa ctgtcttcaa ttccgcattc
    16681 aagtgttcaa agacttgacg cacaccgaca ctaccaccga gagccaagcc ataaataaca
    16741 gggcgaccaa tagctaccaa gtctgctcct gaagccaagg ctttaaagac gtgttgacca
    16801 cgacgaacac cagagtcaaa gacaatcggc acacgtctat caactgcttc tgccacttct
    16861 tgaagcgagt caaaggcagc tggtccaccg tcgatttgac gaccaccgtg gttggttacc
    16921 cagataccag aagctcctgc agcaagtgaa cgttcaacgt cctcacggca ttgtggtccc
    16981 ttgacataca caggaagacc agagtattca gcgataaatt ctacatcgcg tggagacaag
    17041 cgttgtttag ctgatttgta aacaaagtcc attgatttac cagcaccttc tggcaggtat
    17101 tcttcaacaa tcggcatgcc aactgggaag acaaaaccat tacgcttatc cacttcacga
    17161 ttccccccta cagtagcatc tgccgtcaag acaatcgctt tataaccttc agccttcaca
    17221 cggtccatga tgtggcggtt gataccgtca tccttactaa agtaaaattg gaaccaatgg
    17281 ggtgtccctt gaagggcttc agaaatctct ggaaggtcaa cagtagagta agagctggtt
    17341 gtataaagag aaccaaactc atgcacacca cgcgcagtcg ccacttcccc ctgttcattt
    17401 gccaatttat gagccgcaac aggcgccata atgattggtg aagatagttt ttcacctgca
    17461 aattcaatct ctgtacttgg attttcaaca tcgcaaagtg tatgaggaac gatgagtttg
    17521 tggttaaagg cgcggatatt ctctcttaaa gtgaaagtat cttccgcccc actagcgata
    17581 tagccaaatg ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg
    17641 atgaagtcta catgaccttc tgcattgctt gttttatatg acataaaatg ccctccttga
    17701 ttaagtaagc gtttgctttt tactacacaa ctataataac tcttttttca atcattttca
    17761 agagttttgc ttaaaaacca tcttattttt tcatacaata tactagccct actttcctta
    17821 aactctaaac cttagtctat attaagtgaa tcgttgagat tttttgctgc caggcatttg
    17881 aactactttt ttatttgcgg attctatcta ctaatactat aaaaaaaaca agtgaataag
    17941 acaccagaac atcctctaat aggacctatg gacttatatc agtcccatat atactgttta
    18001 agcaagatac tatcctagtt gacgctaact tcctatccca cttattaatt ttttatttat
    18061 agtgaatctg aacaaatcaa ttggggaatc caagtcaatt tctagtactt tttgaacagt
    18121 ttcagcgtac tatcgtaaaa tgaaataaaa catgcacaaa ttgattaggg aatttaaacc
    18181 aatttctaac aatgtcttag aaatcaaagt gtactatttc aacttcaata tactacactt
    18241 cattttctcc ttaaattcag tctctttttg aatcaaaaaa tcctctggta agagccagag
    18301 ggtaagaatt tatttcattg ttgggaagag caatacatca cggatagttg ttgtatcagt
    18361 gaggagcatg cagagacggt cgataccgat tcccaaacca cctgttggtg gcataccgta
    18421 ttcaagagcc tcgatgtagt catagtcgat gcctgtcgct tcatcatcac caagttcttt
    18481 agctttagct tgggcttcaa aacggctaag ttggtcgatt gggtcgttga gctcagtaaa
    18541 ggcattaccg tactccttag tcatgataaa gagctcgaaa cggtcagtaa agcgttggtc
    18601 ttcaggattt ttcttagcga gtggagatac agctactgga tgtccataga caaaggttgg
    18661 ttggattaaa gtttcttcaa caaactcttc aaagaaggca ttgatgatgt gaccaacctc
    18721 agtgtagtgt ttctcaactg gaactttctt ctcagcagcg atagctttag cttctttcaa
    18781 agtcatgtct tgccagaaat cgacaccagt aatttctctg atagcatcca ccatatgaac
    18841 acgcttaaat ggttcgttaa tcttgatttc agtaccttgg tagttgactg ggccatcgcc
    18901 cttaactgat ttagcagcat gttggataat gccttccgtc aagtccatga tatcttggaa
    18961 gtctgcataa gcttggtaaa cttcgataga agtgaactca gggttatgag tagcatccat
    19021 tccttcgtta cggaagatac ggccaatttc atagacacgt tccataccac ccacgataag
    19081 gcgttttaag tgaagctcag tcgcgatacg aagcaccatg tcaatgtttt gggcattgtg
    19141 gtgggtgata aatggacggg cagcagcacc accggcttca ttatgaagaa caggtgtttc
    19201 cacttcaagg aatccttttt ggtcaaggta acgacggatt tcagagatga tttttgaacg
    19261 agtgacaaag cgttcaaagc tttcacgatt agaaatcaag tcaaggtaac gtttacggta
    19321 aattgtttca acgtctgtca aaccatggaa tttctcagga agaggacgaa gagccttaga
    19381 caagtgtgtg atgtgggttg ccttgataga gagttctccc atatccgtac gcatcacttc
    19441 accttcgaca ccaaggaagt caccaaggtc tgcttttttg aagatttcgt agttttcttc
    19501 accgacagca tccttacgaa cgtagatctg aatctggcct tcgcggtctt gaaggtgggc
    19561 aaaaccaact tttcctttac cacgtttggt taccaagcgt cctgcgatag tagctgtttc
    19621 gtttttatcg tgtaattgtt ctttatcgag gttggcatat ttatctttta attcttgtga
    19681 atttgcagta cgttcaaaac gttttccgaa aggatcgatt ccttgttcgc ggagcgcagc
    19741 cattttttca cggcgaacga tctgctggtc atttagttct tccatatgtt ctgtagacat
    19801 gggatcctcc tagttttact caaaattgaa tacgatgagt cattttttgc gatactccca
    19861 ttttatcata aataagcaag aaattcacgg ataatcttta aaaactaaaa agaacctgac
    19921 gctaaaatca ctggaaagaa gtgaaagtat cttccgcccc actagcgata tagccaaatg
    19981 ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg atgaaatcta
    20041 catgaccttc tgcattgctt gttttgtatg acataaaatg tcctccttaa taagtaagcg
    20101 tttactttgt atattataaa aatatattaa ctcttttttc aaaacttttc aaatattttg
    20161 tttggaaatt tcagaaattt tatgtctatg ataaaaatcc ttataacggc aataaaaaat
    20221 agatattatc caaagaagat tttaagtgct acaataactg tattatttct agatgggagg
    20281 ttctattttt ggattgatcc attgttgaac aatatctacc actatatcaa aaggcattct
    20341 ttctgacctt gcatattgca gtttggggaa ttttgggatc ctttctgctc ggtttaatcg
    20401 ttagtatcat ccgacattat cgaatccctg ttttagcgca agtagcgaca gcctacattg
    20461 aattgtcacg taatacgccc cttttgattc aactcttctt tctctacttc ggtcttcccc
    20521 taatcgggat tgtcctatct tcagaagtct gtgcaacgct tggacttgtc tttttaggag
    20581 gctcctatat ggcagaatct ttccgaagtg ggctggaagc catcagtcaa acccagcagg
    20641 agattggcct cgctattggt ctgacacctc tacaggtctt tcgctatgtg gttcttccgc
    20701 aagcaacagc ggtggtactc ccctccttta gtgccaatgt cattttcctt atcaagaaaa
    20761 cctctgtttt ctcagcagtg gctttggccg acctcatgta cgtcgccaag gatttgattg
    20821 gtctctacta tgagacagac attgcgctag ctatgttggt agttgcttat ctgatcatgc
    20881 tgctacccat ctcactggtc tttagctgga tagaaaggag gacctgccat gcaggattcg
    20941 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg gttgggcgtt
    21001 acgattggga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
    21061 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggaattt
    21121 atccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt ggctcgaaac
    21181 tttaatatca atatctcagg tgagacttca gctattatca tttttaccct ctggggaaca
    21241 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
    21301 agtggatagg cactcggctt gactaatgtt caactttact accacatcat catcccacaa
    21361 gtcttaagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
    21421 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
    21481 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
    21541 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
    21601 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
    21661 cccatcctcc aaggactttc tctagaaatc aaaaaagggg aagttgttgt catcctaggg
    21721 ccatttggtt gtgggaaaag taccctcctt cgttgcctca acggcttaga aagtattcaa
    21781 ggtggagata ttcttctgga tggtcagtct atcgttgaaa ataaaaaaga ttttcaccta
    21841 gttcgccaaa agattggcat ggtctttcaa agttatgaac tctttcccca tctggatgtc
    21901 ttacaaaacc tcatcctagg ccctatcaaa gctcaaggaa gggacaagaa agaagtaacg
    21961 gaagaagctt tgcaattact agatcgtgtc ggtttactgg ataaacaaca tagctttgct
    22021 ttgctttgcc cgtcaattat ctggtggaca gaagcaacgt gttgcaattg tccgtgccct
    22081 cctaatgcat ccagaaatca tcctttttga cgaggtgact gcttcgctgg atccagaaat
    22141 ggtgcgtgag gtgctggaac ttatcaatga tttggcccaa gaaggccgta ccatgatttt
    22201 agtaacccac gaaatgcagt ttgcccaagc cattgctgac cggattatct tcctcgacca
    22261 agggaaaatc gctgaagaag gaacagctca agccttcttt accaatccgc aaaccaaacg
    22321 agcccaggaa tttttaaacg tctttgactt tagccaattc ggctcatatc tataaaggag
    22381 attcttatga aactattcaa accactctta actgttttag cacttgcctt tgcccttatc
    22441 tttatcactg cttgtagctc aggtggaaac gctggttcat cctctggaaa aacaactgcc
    22501 aaagctcgca ctatcgatga aatcaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga
    22561 gataaaaaac cgtttggcta cgttgacaat gatggttctt accaaggcta cgatattgaa
    22621 ctagggaacc aactagctca agaccttggt gtcaaggtta aatacatttc agtcgatgct
    22681 gccaaccgtg cggaatactt gatttcaaac aaggtagata ttactcttgc taactttaca
    22741 gtaactgacg aacgtaagaa acaagttgat tttgcccttc catatatgaa agtttctctg
    22801 ggtgtcgtat cacctaagac tggtctcatt acagacgtca aacaacttga aggtaaaacc
    22861 ttaattgtca caaaaggaac gactgctgag acttattttg aaaagaatca tccagaaatc
    22921 aaactccaaa aatacgacca atacagtgac tcttaccaag ctcttcttga cggacgtgga
    22981 gatgcctttt caactgacaa tacggaagtt ctagcttggg cgcttgaaaa taaaggattt
    23041 gaagtaggaa ttacttccct cggtgatccc gataccattg cggcagcagt tcaaaaaggc
    23101 aaccaagaat tgctagactt catcaataaa gatattgaaa aattaggcaa ggtaaacttc
    23161 ttccacaagg cctatgaaaa aacacttcac ctaacctacg gtgacgctgc taaagcagat
    23221 gacctggttg ttgaaggtgg aaaagttgat tagtcattaa ctcttaaaag gaactggatt
    23281 ttaagatcca atcccttttt aagattttac ctataacatc ctgagtctat ctaagatgtt
    23341 caatctgaac acagtgtaca tactttatct tctattgcat atactttatc acataagata
    23401 cgaatatcct cttcactatg actagcaatc aaaattgttg tccctttttc actagagagc
    23461 tttctaaaca atgttctcat attttctaca cttgatttat ccaaggcatt cataggttca
    23521 tctagtaaaa gaatagaggg attctccata attgcttgag caatccctag ctttttcctc
    23581 atacctagcg aataagtttt aactttctgg tctttttgct catatagacc aactattttc
    23641 agtgtatcat tgatttcctg attaccaact actcctcgta tgcttgccaa atattgtaaa
    23701 ttcttaaagc cactataata atttataaaa ccaggttctt caatcaaagc tcccaaatta
    23761 gctggaattt ttctctcagg aacaatattt tccccattga ttaacacttc tccataagac
    23821 ggactatata aaccagctat taatttaaac aatacacttt tccctgagcc attcgcacca
    23881 gtaattccta taatttcccc ctgtttacaa ctaaagttaa ggttttgaaa aacacatgtt
    23941 ttttttaatt ccaactgaat attttttaat gtaattattt cattcattct ataaacctcc
    24001 tcttttgacg agtgaaatag aaaatgcttt taaaaagaaa gactaaaaat agcaactgaa
    24061 gaaataaatc tcgtcctata tctccattcc ctcgatttaa aatataaaat agataattag
    24121 ttcgatttcc tacaaataga ccaccaaaca caatcatgag taaaaagaag ctaacacaag
    24181 aaaagttcat ttgctcattc gctcctagta cgtataacat aaagcaaaac aagactaaca
    24241 cacaagcatt caaagaatca actataaaca aaactcctat atcccagttt ggtaactgta
    24301 acataaattg aatcactaga acttttacca tgattaaaat gagtccataa agaaaacagg
    24361 tccaaatctg atacctaatc cagagcttaa tagaagaaaa tcgaatcact tccataaaga
    24421 aatcggatgc tcttctacga tatacaactg ctagaaaaaa tgtatgaata ataaaccaat
    24481 gaagcaacca tatagataag actaaaaaag agttttgact cagattaggc ccttttaaaa
    24541 tttctataac aagtctatca tttccttcta accaatacca taatcctaaa caaatcaata
    24601 tccaaaaaag aacataaccc caaaagtact tggtatagat tatctgattc aacctccaca
    24661 tgtgactact taactttccc atttccaact tttacactct cctccagttt ctatgaacag
    24721 aaaatacagt caatggaatt atgatagata gtaatgtaag ccaataaatc aatgcatacg
    24781 gattggaatt taccatatac tgaaaaattg gcaataatcc aattatccca ttgtccaact
    24841 gataaatcca gaataaggat tctacaaata aaaaagtaaa cagaaatact aagctcatgt
    24901 ttgatttttt aaaccaagaa aaactgctaa tagtaagtaa ggataaaaag aaatagtatg
    24961 ctatataaga gaaaaaaaat cctataaaaa aactagcatt gtttgcaata cttataccat
    25021 aaaattctct taaaaaatca acctccttta tctccaaaga gaagctaaaa ccattactaa
    25081 atgcaatcag aaaaatcaat aaaaataaag tcgccgtcca aatccccgta ctaagagctg
    25141 ctaatttgaa actaaaactg gtaaagtgct taattgattt cagacgaata cgacactcca
    25201 acctattaaa atagttattc atcaaataaa aaaagaataa tatatatgtg aacggaaagc
    25261 aatatactcc agtcgtcata tcttgaagta aaactaagat ccattctaat acatttggat
    25321 ggattgaata ttggcgacag cgcaataaat atactgtact agataaaaca caggatagca
    25381 gtaatataaa ataaaccaat actgctaaga aatctttttt ataaaattga acaaattgtt
    25441 tcattataca tagtcctctg aatgtagaaa aaatgtacca taaacaacca aacaactaac
    25501 aaataaaata aaagcaagat gcccactaac taaggaaaga ctgatatctt tctgatatcc
    25561 caaagctagc gttgtcacag gttctaagta agatagccct aaaatagccc ataaaatacc
    25621 accaaccatc atataggcaa ctgggatgaa aatagctcct aattttttct tcactagcaa
    25681 agcactagct agtccaaaaa tagagaacac agcgccccaa actccatacc agagagtcgt
    25741 cacaagacta tagagaaact gattggaatc aaataattct tttaaggcac cactataatc
    25801 tccaatataa atttcctgat aaggagtcac taaaagatta attcctaata ataataaata
    25861 ggggagaaaa aagactagaa aagaagaaat aattgcagta ctacctacaa tagctagata
    25921 cctcttttta gaaattcggc acaattgtgc tgttagaaaa tgactctcag catcctctat
    25981 tatctgacta gaatagggca gtgtacagat aagtgcagct actaggctaa tcggtgaaaa
    26041 tcctcgaata gaagaagcgg caaaaaaaat cgataaacct tcaattttat aaataccatt
    26101 gaaagcaagg aaatttccta aactcatgca aagaagggtc aaaaataaag acatataaaa
    26161 ccgaggtgat tgaacgactc gtacaagatt acaaatgaaa aattccatcc ttactcctcc
    26221 ttataataaa aatagggtgt agcattcttt tttcatgcta cacccacaat caaccatctt
    26281 taaggcttac tctgacaagt aagttaataa gaatctggac tccaagaacc tgaagtatga
    26341 attcttacat aatttccaaa ttgtggcgcc atagctaatc tagtaccaga accaatataa
    26401 ttgtcaccac ctccattata gtacatgaca atcctagagc cagaccccaa tgaatatacc
    26461 ggggtaatat ctgacccact ataggcgcta cgaatagagg tatttaacct tttaccgcca
    26521 ccagtgctgt cactattatt aattccagca gaggcgtttt ctttctcaag ctcactagtt
    26581 gtatccgaac cccaacgcgg caacgttaaa tcataatttc caatctgtct agctaaaact
    26641 gtagggagaa acaaactaga tgcaattgta actacgcaaa aaaggaatat atttttcttc
    26701 ttttcatgac atcgtcctct taagaagtga taaacaagat agttgattga tcaatttgat
    26761 acatattaca ttttcattat atcaataaaa gaaagcgttg tcaattattt tatttaaaat
    26821 attgtcatat tttaaataaa atggtaaaag agactcggta gcctcgtctc tctttatctt
    26881 actgacctaa ccttcttgcc aattttcttg gtcttcttta aagcgtttta gaagatcaag
    26941 gccctctggc gtgatgtaac cttcttcttg ggctagatgg ataagctcgc tatagtttga
    27001 aagcgtcaca agtttaacac cagcatctgc aaagttctta tctgcttttg gcaattggta
    27061 gctgaaaatc gctacaactc caagtacatc tgctccttct cgcttggctg ctgctacagc
    27121 ttcaagaact gaaccacccg ttgaaataag gtcttcaacc actaccattt tttgaccttg
    27181 agctacgcga ccttcgattt gattaccagc tccgtggtct tttggtttgc tacggatgta
    27241 ggcaaaaggc aagtccatct tatcagcaat aatggctccg tgtggaatcc ctgctgttgc
    27301 agttcctgca atcacttcta cttcaggaaa ggcttctttg atagcttcca caaaaccatt
    27361 ttcaattagg gtacgagttt ctggataggc tagtgtcaca cgattatcag tgtaaatcgg
    27421 tgacttgata ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa cggcttggat
    27481 tttcaagagg tggctagcga tatctttagc aagtgtcatg gtattctcct tttatttttc
    27541 taatctagtt ctttaattcc agtcctgtgt ccattcatcc ttgatggcat gataagctgc
    27601 aacaggatcc tcagcttggg taatgggacg tcccactacg atatagtcac tgccgatttg
    27661 ataggcatca gcaggtgtca tgactcgttt ttgatctcca actgcaacac cagctggacg
    27721 aatccctggt gtcagacaga taaaatctgg attggtagcc tgcttgatga cttgtacttc
    27781 ctgagccgag caaacaacac catccaagcc agcttcagct gtcttcttgg catagtgaat
    27841 cacagactct tgcagactgg tttggatatt ttgaaactcc tgcatctgag cttctgacgt
    27901 tgatgtgagc tgcgttacag cgatcaattt ggcttgactc ccaagacctt cacgcgccgc
    27961 cttcatcatc tctacaccac cagccgcatg gacattagtc atatcgacac caagctgaga
    28021 caagaccttc atggctgact tgactgtatt aggaatgtca tgaagtttga gatccaaaaa
    28081 gacactatga cccaaacctt ttaagtagga cacaatctca ggccccgctg cgtaataaag
    28141 ctccatccct accttgagat aaaggctttc ttctgctggg aaaagagcta aaaattcctt
    28201 gaccgcctca aaactaggaa aatcaagagc aatgattgga cgatgttctc gcataggttt
    28261 ctccttttac ctttactagt gagagagtct ggccaacaga agccacgaaa aaaggaacct
    28321 gccaacagca aggttccacg aaaaatgggt agtctccacc ctttcaccgt ctaaccttag
    28381 ctgcctctct ggactgcttt aaaggttttc tattattcta ttatttctac tagcacttgt
    28441 caagtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag cgacgcgatg
    28501 agcgctgggt cgtttgattt cgattgctct cttcctcttg ttttttctgt tcttcttcct
    28561 gttttttctc ggcttccttg gcctcttgtt tggctttttc ctcagcctcc ataattaatt
    28621 tatccgccac agtgtaactg taaattccag cttccatgtc gaccacactc ggttctgaca
    28681 attgtggctt aatcttactg taatatggca gtttcttact catttcagat agaggaacca
    28741 agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc ttgcttgggg
    28801 ctaattccac cttttggata gccgccttga gttctgggct aatttgagca agttctgaga
    28861 caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt tctggtaaac
    28921 tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga taatgatttt
    28981 caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg aacttagttg
    29041 gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc tgcttttcat
    29101 attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg cctgaagcct
    29161 gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct ttcatggtcg
    29221 cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga aataaaatcg
    29281 tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt tcctttgtag
    29341 cctttttaga aagcttttta tcctgttcct ccttctcttt agactctggt tcttctttct
    29401 cttctttctc tttgtcagcc tctgaggatg ctactttttc ttcagactct tccttagctg
    29461 attctgaatc ttcctggtct gtttcactct cctggtcctg tttgtcctct gacttctcag
    29521 attcttctcc cattcgagct tgtctttcct tttccttctc ctcagctaga gccgcctctt
    29581 cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat aactctttca
    29641 attcttcgag gatttctttg tcctcatttt tcttatcttt tgacatttac tttccttatg
    29701 ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc ttagaagcct
    29761 tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc tcttccaaac
    29821 tatccaaggt caaatcgctt tcttgaaggt cttctgcata gccttttttt acaaagtaag
    29881 ctgcattttc aagctggtca ccacgactag cttcacgacc aagcggcaca atgacatgca
    29941 attttgctat cgccaagagc tcaaaaatcg tattggcacc acctcgtgtc acaacaatat
    30001 cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga aaaagatttt
    30061 ggctcaactc attcaggcta gaatctccag ttagattgat aatattgtag cgctctgtta
    30121 gttctttctt atggtctgtc accaattggt taaagacacg agcacctgca gaaccgccaa
    30181 caaacaatac agtcggcaat ttatgattaa agtggctttg aatatccacc aattcatctg
    30241 gttctggatt tttttgatct gaaaccttgg tcactgctcc cacatgctca accttagaca
    30301 aactcgaagc ttgctcaaag gttgaataca tcttagtcgc aaatttatag gcgattttat
    30361 tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct gacacacgcg
    30421 cagcgataac aggcggtact gagacaaagc ccccctttga aaaaagggtc tgtggacgaa
    30481 gtcgcaacat gataaagagc gattggacga ttccccagca aactttgaag acgtccagca
    30541 tattttgcca agagaaatag cgacgcaatt ttccagtcgc aatagaatgg aaggtgacat
    30601 ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg atatagtgga
    30661 cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta acgtgtccaa
    30721 ccgtcccccc acctgtaaag acaatttttt tcatattatt cttttaactc cgctactgtg
    30781 tcgataaaga ggtcgccacg tacttcaaag ttagcataca tatcccagct ggcattggca
    30841 ggactaagaa gaaccacatc tccttgagtc gcaagctcat aggccttgcg ggtcgcatct
    30901 gcaatatctg tcgcctccac ataagcgaca ccagccttgt ctgctgcccg tttgacacgt
    30961 tctgcagatt gacccaggat gaccatcttc ttgagtccag taatgtctgg caccaattcg
    31021 tcaaactcat tgccacggtc caaaccacct gcaatcaaga cgaccttgct gttatcaaat
    31081 cctgacaagg ctttttgagt agccaagata ttagttgatt tactgtcgtt atagaattta
    31141 acacccttga tgtcatccac aaactggaga cggtgtttga caccaccgaa ggctgaaaga
    31201 gtttccttga tggtttgatt gtccacacca cgaagcttgg ctacagcaat agtcgcaagg
    31261 gcattttcca cattgtggct acctggaaca ccgatttcat tcgctgccat gactacttca
    31321 ccacggaagt agagttgacc atcttccaga taagctccat caaccttttc aagtgttgaa
    31381 aatggtacaa cagtggcttc tgtcttggaa gtcaagtctt ttgccaagtc ttgattaaag
    31441 ttcaagacaa ggaaatcagc tgctgtcatc ttgttctgga tattccactt ggctgctaca
    31501 tattccgaaa atgacccatg gtagtcgata tgagttggca tgaggttggt aataaccgca
    31561 atctctggat ggaattcttg aacacccatg agttggaaag aagaaagttc cataacaagc
    31621 gtgtccttat ctgatgctat ttgagcaacc tgactagctg gatagccgat attccctgat
    31681 aaaagaccat gttgcccagc agcagtcaaa acttccccaa tcatagtcgt tgtggttgtc
    31741 ttaccgttcg atcctgtgat accaataatc ggtgcttctg aaatcaaata agccaattcc
    31801 acctcagtca agactggaat tcccttggcc aaagcctttt caatcatggg attgttgtag
    31861 gggatacctg gatttttcac cataagggca aactcttcat ccaagagttc caaaggatgg
    31921 ccacctgtaa tgaccttgat cccttcttcc agcaaacttt gggcagctgg attgtcctcg
    31981 aaaggtttcc catcatttac tgtcacaatg gcacctagct tgtccaacaa acgagctgca
    32041 gattcaccag acttggccaa acctaaaaca aggactttct tatttttaaa ttgatctatt
    32101 actttcatgt ctcgaactcc atttctactc ctactatttt accattttta tggaaataaa
    32161 aaagccacaa agtgtgtttg tgactctttc ttctaactga atcttaccat atcatctatg
    32221 tgataaatcg gtaactcgaa tgacctgatc cacttgttcc caaatcagag gattgtgggt
    32281 cgcaataata atggtccgat tcggattttt taaagattct aggatggaaa gtaattcctc
    32341 agagtttttg gggtctaagg aagtggttgg ttcatctgcg aggatcaaag gtggatcctt
    32401 taaaattatc ttcgctaatg caacacgttg tgcttctcct cctgataact caaatatagg
    32461 ttgcttcaaa tccaaataag agaggtttac acagtttaga gcttgtttca tcaaagagat
    32521 tttctctttt tccttcaact ttttaccaac taaacccaga ttgagattct ctttgacggt
    32581 ttggctttca attaagccaa aatcttgaaa taagtatccc aagtaatctc taaagaaaac
    32641 agaaggcttg atgtccttaa gagaagtacc atcatagatg atttgtcctt tgtcatatgg
    32701 ctctaatcgt ccaatcatat tcaagaatgt tgtcttacca cagccacttg taccgattaa
    32761 ggcataaatt ttcccacctt caaaatgaag atttgtatct gaaaatagct gacggcttcc
    32821 aaatttttta gatatattct ttagttcaat catcctattt tcctttcata attgtcatag
    32881 aaacacgaga ttctttctgc gcttgacggt aaagcgtcag aactgcacta gctagaaaga
    32941 ctaataaagt gagcaagcca atcaccaagt ctcgactgct taaaataaag agactagcac
    33001 caaatacaaa actggcaaat tgactaacca tatactgagc atgtgtttca aaaaatcgta
    33061 aacctgaaat tcgtttaatc aaaatatctc ggcggaattg ctcgaaatat agaagattga
    33121 cagaataaaa tagtaacaag gaactagcta tccccacaat agctcctaag attaaagttg
    33181 ctgtttcagt ttgaacttca ttataacgag ttagataaac acttcttcct tctttaagat
    33241 aggatacttg ctcataaatt ccagctttct tcaagagttc tagcccactc tcatatcctt
    33301 tgataaagag ttgttttcca gcattgatag accaactaga taaggatata aaactatcac
    33361 ctgtagaagt cggcgtgaat accactaaaa tcggatcagt caaatactga gtagatacgg
    33421 gattctcacc gttattataa acaaaccgct tttctcccat tgaaagataa ctaacgtgcg
    33481 ctttcatctc ataatccaaa ggagcacttg cctcctcacc agattttcca taataactca
    33541 atctttcttc aaaaactttc ttaagttctg cttctcgaga gcgcaaatgt tctgggagca
    33601 agaggataaa ctcacctttt tggagatggg ctaacttctg tttggtctca gcatctacca
    33661 cgaccttttc cttgtccaaa taactgggac taacatagag cgtattagca tctggactat
    33721 aggtatccag tgtctctccc tgttcatttt ttccttgtgg attggcaaaa tggagcagat
    33781 tatcctttac ataaagagct tgttcttctt cgattgcttc cttggcaaag gcataccact
    33841 tgctctgatt ttctgtatct tttcctctat cacctaagcc aaaagaaatt tgataatagt
    33901 ctgctctatc ctgccatgct tgttttgaaa tttcaagttc tttcaatcgt tggtaagaca
    33961 tcaaacctgt cttaacagcg tagcctactg taaagacagc aaccaactga cacaataggg
    34021 ttaaaatcat caggcgttta aggggtaatc tccccttaat aacgggaact aatgctttgt
    34081 aactcaaact cattagataa agaagcatta gtaaaattga aatcgccaat aaaaacaaca
    34141 gatagaaact aatcccaaaa ccataggtgg ctaacaagat aggataaaac aaaccttgac
    34201 taaaaagaac gactccccca cctaggaagg aaaggagggc tgatagaagg agccatttga
    34261 tatcagtaga taaagaatgc cccatgatgg ataagagagt ctgaccagaa aagagtttta
    34321 tacctgctgc tctcatttcc ttaatccgag tgataatcac taaagcaaag aaagataagc
    34381 caaatattgc taaactaatt aaaataaggg gatttagtaa tattcgaaaa gcaagaaaat
    34441 agggcggtat ctttcggtca gcacttgctt tataacccaa atctcctaat ttatcggcaa
    34501 gcttttcttt cgtcaaggag cctgacaaaa ggagataact atttagcgga tcactacgtt
    34561 cacgactttc ttggctagct tcttggaatt cttttggtaa agttccctga ccataagttg
    34621 cataagtaaa gtgagtcgtc ccatccttac tcggctctac aattcttcta gctattaaac
    34681 tctgttctga gtttgcaaaa ttctccaatt cctgttcaaa tacctcacgc gtcggttcct
    34741 gagtatcttt tttgacacga agtaaagaaa cggaatcata gcttgcatat aaatattgtg
    34801 gcgcacgtaa gacaataatc caagcaagga agaagctgag aaaaaagttg ataataatat
    34861 gaatagtttc ttcatagtag actccttgta aacaaaattc cccctgtaat ttcttacaag
    34921 gggaacgatt taaatcaatg aacgattagt cataatcaca gtaaaatgct acttgttctc
    34981 cccatttagt ccaaatccat gcataggagg tttttccagc agaagcttct cctttatctg
    35041 aatgactatt ccatctactt acaagagaag aataatgata ttttttacca tgatagtaat
    35101 ttgaaaaagc ccaaccacct cctgaacctt ctccatacgt ccatactcct ccatctggat
    35161 attgtacagc agctgatgca gctcccaata atgtaaaact tgaaataaga gctagagcaa
    35221 gtaatctatg ttttttcgtt ttcattttat tttttctttc aaaaaaagca caccttgagc
    35281 aacaatgcaa caaaataaac cctcctctct cttttgttga aaccgctttc ttatgtgata
    35341 aaaatatcat ttttattatt tgttgtcaag gaaaaaatcg aattttttag atattttact
    35401 acattgcctc tatgaataat attatatagt agttttattt taaaataata tgcaaccagt
    35461 actaaccaaa tataaaatag atgccattaa cgaattttat tcaagttttt cccattcata
    35521 ctatccaagc aaaagagatg atgttatagt acaaaacaat tcaaactatt gtaaaattcc
    35581 tagcaaaaaa gagagccaaa actctctttt ttatcttctt ttactttttt tgactggcat
    35641 gagtgtaatg tctctaacac taaagtaagc taggatcaac atggctattg ctaggaatat
    35701 ttctgttggt aattgaaaaa ttttcagaaa agatagaacc aataaaatca agagtgccac
    35761 taaaatacat accatagcga cgatattgac tgtcccttta atgctttctg gtgtcgcaaa
    35821 tacatagagt aggagcagta aaattcctag gactaaatag accatctttc tctctttcta
    35881 gctcttattc agctgatttt ttcttcttgt tagctttctc acgctctgct ttgttaagga
    35941 tttgtttacg caaacggata gactcaggcg ttacttccat gtactcatcg tcgttcaaga
    36001 actcaagaga ctcttcaagt gtcaagatac gaggcgtctt gataacagct gtttggtcct
    36061 tagtagctga acgaacgttg gtcatttgtt ttgccttcgt gatgttaact gtcaagtcat
    36121 tttcacgaga gttttcaccg atgatcattc cttcataaac ctcagtacct gggttgacaa
    36181 agatcgtacc acgttcttcg atagacatga ttgagtaagt tgtagcctta ccagcatcga
    36241 tagaaacaag ggcaccacgg tgacgtccac caatttcccc tggaatcaat ggcaagtatt
    36301 ggtcgaaggt atggttcatg ataccgtaac cacgagtcat tgacaagaac tcagttgagt
    36361 atccaatcaa accacgcgct ggaacaagga agaccaaacg agtttgacca ttaccagttg
    36421 aaatcatatc caacatttca cctttacgtt cagaaaggct ttggataaca gacccttggt
    36481 attcttctgg agtgtcgatt tgtacacgtt caaatggttc acatttaaca ccgtcgattt
    36541 cttttacgat aacttctgga cgagatactt gaagttcata gccctcacga cgcattgttt
    36601 cgataaggat tgacaagtgc aattctccac gtcctgaaac agtccattta tctggtgaat
    36661 cagttgggtc aacacgaagg gaaacgtctg tttgcaattc tgcctgcaag cgttcttcca
    36721 ccttacgaga agttacccat ttaccttctt taccagcaaa tggtgagttg ttgaccaaga
    36781 aagtcatttg aagagttggc tcatcgatgt gtaggattgg aagagcttct actgcatctg
    36841 tcggagtgat ggtttcaccg acaaagatgt cttccatacc tgaaacggca atcaagtcac
    36901 ccgctttggc ttcttggatt tcacgacgtt ccaaaccaaa gaaaccgaag agttttgtaa
    36961 cacggaagtt tttagttgta ccgtcaagtt tagaaagggt aacttggtcc ccaaccttaa
    37021 ctgtaccacg gaagacacga ccgataccga tacgtccaac gaagtcattg tagtccaaaa
    37081 gtgacacttg gaactgcaaa ggctcatctg agttatctac tggagctggg atatggtcga
    37141 taatcgtgtc aaagattggt gccatagtcg cttcttggtc agctggatca tctgacaatg
    37201 aagaagttcc gttgatcgct gaagcataaa ccactgggaa atcaagctgg tcgtcatctg
    37261 caccaagctc gatgaaaagt tccaagactt catccactac ttctgctgga cgagctgatg
    37321 gcttatcgat tttgttaaca accacgattg ggacaaggtc ttgttccaag gcttttttca
    37381 atacgaaacg agtttgtggc atggttcctt cataggcatc tacgaccaag acaacaccgt
    37441 caaccatttt catgatacgc tcaacttctc caccaaagtc cgcgtgtcct ggtgtgtcca
    37501 taatgttgat acgagttccg ttgtaagcaa cggcagtgtt tttagcaagg atggtaatcc
    37561 cacgctcttt ttcgatatcg tttgagtcca tagcacgctc tgccaattca gtacgtgcat
    37621 caagcgtttc tgattgtttc aataattcgt caaccagggt tgttttaccg tggtcaacgt
    37681 gggcgataat cgcaatgtta cggatatctt ctcttaattt tgtcatgatt tcctctataa
    37741 tattcaaaat ttattttcta actgaacgat tataccataa tttcaaataa ataacataac
    37801 tcaagcaagt gtaaatgttt tcactccgct tttcttttca cgtcaagcct tttcaaagca
    37861 agcgacttat gataagatag gcacagtatg cgtttagata atttattagc ccaagaaaaa
    37921 gttagccgaa aggccatgaa gcaagcactc ctcagagggg aaattctagt cgatggttgc
    37981 ccagcccgct ccctagctca aaatatcgat acaggactac aagaactcct ttttcaggat
    38041 cgaatcattc aaggctatga acacacctat cttatgcttc ataaacctgc tggtgtcgtt
    38101 acagccaaca aagacaagga acttccgacc gtcatggact tgcttccatc tgacatccag
    38161 tctgacaagc tctatgccgt cggccgactg gaccgagata caacaggact ccttctcttg
    38221 accgataacg gtcccttggg cttccaactc ctccatcccc aatatcatgt cgataagact
    38281 tatcaagttg aggttaatgg acttctaaca cctgaccata tccaaacctt tcaaaaagga
    38341 attgtctttt tagatggcac tatctgtaaa cctgcaagac tagagattct atcagcaagt
    38401 ccttccctca gtcaagcctc tatcaccatt tcagaaggaa aatttcatca aatcaagaaa
    38461 atgttcctct cggttggtgt taaggtgact aacctcaaga gaatccaatt tggggacttc
    38521 acattgaacc cagatttagc agaaggtaac taccaccctt tgaaccaaaa agagttacaa
    38581 atcattaaaa actatttaga gatgagtcga taaaacaaaa aaagctttaa aactaaagct
    38641 tttttctttt atttaccgaa aaattaaggc gattgctaca atccagttaa ctacagaaat
    38701 cacaattcct aagatattaa gaatcttttc tattttatag tctaattgtg actctttttg
    38761 gtatgaaata gccaagacca atcctatgat acccaaaatc aggcctacaa ttggaaataa
    38821 caaaccaaga ataatcgaca agatacccac aaaaagtgga tttttcttct tttctttcat
    38881 gttctaagaa ctctttaaat tttatacaaa ttaattatac tataaaacaa tagcttcatt
    38941 ctatcattcg actaatttgg aaataaggtt agctagtctt cactttccct ttccaagaat
    39001 ccaagccata agaaaggata taaatctcag aaaaaccttg ttttttcaag taaagagctg
    39061 catttgtaac tcgttgcgca cgttggtttt cgtagagaag gacaggttta tctttacgaa
    39121 gggctgcaag actagttttc aactgacttg aaggaatatt gcgtgcacca aggatatgtt
    39181 ttctgtggaa ttctgctggg tcgcgcaaat caatcaattg acccgtacga atcaaggctt
    39241 caaactcctc attgtccaca attttagccg cacggcgaat acgaagatag ttaaagccca
    39301 tccacgccaa cattgctagt ataagtgccc acaaaatcca agtaaccatt agttcttttc
    39361 tccatttttc tcaatataat ccaattctac cttgtgctct ctgcgaagaa ctgcttctgc
    39421 ctctagatag tctaatttat ccatcaaccc tgcatcgtaa atccgagata gttccaactt
    39481 catcagttca atatcatata agcgttttcc catgtaaaca ataataccaa atcgtttgag
    39541 gaattgctgc acatcataga atgttttcat aagactcatt ctagcaaaat tttgtgtttt
    39601 tttcaagaag agactcacac aatgctcctt attttcctat cttctttagc gattctaagg
    39661 caagtatggt acaataaaaa catgagaatt caacaattac attatattat caaaatcgtc
    39721 gaaactggct ccatgaatga ggcagccaag caactcttta tcactcagcc aagtctctcc
    39781 aatgcagtgc gagatttgga aaatgaaatg ggcattgaga tctttatccg caatcccaag
    39841 ggaatcacct tgacccgtga tgggatggag tttctctctt atgcccgtca ggttgtcgag
    39901 cagacccagc ttctggagga acgctataaa aatcctgtcg cccaccgcga actctttagc
    39961 gtttcgtctc aacactatgc ctttgtggtc aatgcctttg tctctttgct caagaaaagc
    40021 gatatggaga aatacgaact cttccttcgt gaaactcgga cttgggagat tatcgacgac
    40081 gtcaagaact tccgcagtga ggtcggggtc ctcttcttaa acagttacaa ccgtgatgtt
    40141 ttaaccaaga tgctggatga caatcacctg ctagcccacc atctcttcac agcgcaaccg
    40201 catatctttg tcagcaagac caaccctctg gcaaagaaag acaaggtgaa actgtctgat
    40261 ttggagaatt tcccttacct cagctatgac caagggacgc acaactcctt ctacttttca
    40321 gaagagattc tttctcagga acaccacaag aaatccattg tggtcagtga ccgtgccacc
    40381 ctctttaatc tcttgattgg tttggatggt tataccattg cgacagggat tttgaacagc
    40441 aacctaaacg gagacaatat cgtttctatc ccactggata ttgatgaccc gattgagctg
    40501 gtctatatcc agcatgagaa aaccagccta tctaagatgg gcgaacgctt tatcgactat
    40561 ctactagaag aagttcagtt tgatagttga gaaatgataa gaaccaatat gtaggctagc
    40621 aacaacctgc acattggttc tttttactta taattaaaag tttcccctgc caacttatca
    40681 gctagcttgg gaaagagagt ataaaactta tgggctaggt tcaacaaaat cgggagattg
    40741 agttctcgtt tatttttgcc tataatcttg acaatctttt tagccactgc atctgcctct
    40801 aagaggaagc ggtcaaccga tttaagataa gttccatctg ggtcagcttg gtcaaaaaat
    40861 cctgttcgga ttggacctgg attgactgtt gtcacataga ctccataggg cataagttcg
    40921 agtcgcagag catttgaaaa accaatagcc gcaaacttgg tcgctgagta aagactagac
    40981 ttgccagtag ctattagacc tgccatgctg acgatgttga tgatatgccc tttgctgctt
    41041 tccttcatac gagccgcaag gtgacgagac agattcatca gggcaaaggt attgacctca
    41101 aacatctggt gaatatcttt atcagcaatc tggtcaaatc cctcaaaaat cccgtaacca
    41161 gcgttgttaa tcaagacatc aatcttgcca tagcggagat aaagatcagt taccagagct
    41221 tctagggctg aatcgtcggt aatatcaatt tcaatcaatt ctgcatggga ataatttccg
    41281 tagagttggg ctaatttttc cttatttcta ccaagcaaga tgagttggtc attgggcagg
    41341 agtttgacca tttcttgagc tagaccaccg ctagctccgg taatgagaat agtaggcata
    41401 cttatccttt ctgtgactgc tagatttcca cttcttccaa gtctttgacc acatggacat
    41461 tttcaaaaat tgtggcagcg tccttcttga gtttgcttat atcttttgag aggaaacggg
    41521 cactgatatg gttgagtagg aggcgtttgg cacctgcttc taccgctact tgtgcagctt
    41581 gcatattagt tgagtgacca tggttacgag caattttttc atcacccttg ccataagtgg
    41641 actcatgaac taggacatct gcattgacag ccagacgcac actggcatcc gtttttcgag
    41701 tgtctcctaa aatagtgata atcttacctg gacgtggcgc tgagatatag tctgctgcct
    41761 tgatttcagt tccgtcttcc aaaacaagat cctggccgtt tttgatttta ccaaaaagcg
    41821 ggccgaacgg aacaccagca gccttgagtt tttcagcatc cagcgtccct tctagatcct
    41881 tttgcatgac acgatagcca acacagaaaa tagtgtggtc cagctcctct gcatacacag
    41941 tgaatttatc ggtttcaaga attttaccca gagaatcttg gtcaaactca tggaaatgaa
    42001 tgcggtaggg cagacgagaa cctgacacac gaaggctggt taagacaaat gacttgattc
    42061 cttgaggtcc gtagatttcc aaatctgtct gctcttcatt ggcctgaaag gcacggctag
    42121 aaaggaaacc tggcaaacca aaaatgtggt ctccatgcag atgggtaata aagattttgc
    42181 tgaccttacg tggtcgaatt gtggtttcca gaatgcgatt ttgcgtacct tctccacagt
    42241 caaagagcca aacttcgtta atctcgtcca aaagtttcag ggcgagactt gaaacgttgc
    42301 gggctttaga gggctgacca gcccccgttc ctaaaaattg aatatccatt cgatactttc
    42361 taattaatca atatataaca tggctgtgcg gttttccgat cggaaatagc gtttgccaga
    42421 aaaagcagca gcttcttgca ataaatcctc ttggctgtag cctttgagac gttttcgacc
    42481 atcagccaat ctttccaaat cagtcaaagc tgtgagactt tctaggctga caacttcctc
    42541 gtccttgaca ggtttcatgt aaatcttacc agactcttca aagactaatt gatgggagaa
    42601 aatttgcgca atttcaaaga gcaagtcatc cgagattttc tcctcatttt cagagaaaat
    42661 ccgaccaagg ccgtcactct cataacaaaa accaaaggat ttaccagaca gattaagccg
    42721 aataaaaggc ttattttcta gggtgaaact tggctcagta ttgtaaagat tcagttcctg
    42781 actgagttct gcaaaataat ccgtcgcagc ctgaggactt tttttctgat agagttctgc
    42841 aaagtaggca ttaacaacac ttggcggagg tgtaataagt gttaactgct cctgctctgt
    42901 tttaccagct agaagctgat ccagatagac cttgtccaga cttgtataac ctccatactt
    42961 tagagccaaa gttttaatat cagtcataaa attcttctaa cctccattta tttttctcgg
    43021 aaatgtagcc tgtaatcact tcgccgtctt cctgataatc acgttcttcc agaattgcaa
    43081 cactctctaa atcatgaatc ttgtaggact ttgaaaaagg cactcgcagg gtaaatgctt
    43141 caaaaatttc cttaatctta tctagcaata atgcttgcaa gttttcacga ctgtcctcag
    43201 acttggcaga aatgagggta tatggcgttt gggtaggcgt gaaatcctcc accaaatccg
    43261 ctttattata aagcgtcaag tgaggaatat cttccatgtc caggtctttc atgatggaga
    43321 gaaccgtttt ttcatgctcc tcgtggtaag gattgctagc atcgataaca tgaaccagaa
    43381 ggtccacatg cttgctttct tccaaggttg acttgaaact ggacaccaac tctgtcggca
    43441 aatcttggat aaagccaacg gtatctgtca aagttacttg gagattgcct cccagatgaa
    43501 tactcttggt tgtcgcatcc agagtcgcaa agagctcatc tgcttcatac tgggtcttac
    43561 tggtcaagat gttcatgata gttgatttcc cagcattagt ataaccaatc aaaccaatct
    43621 taaaagtgct agactccaaa cgtttttctc tgacagtcgc acgatttttc tcaaccacct
    43681 tgagctggcg ctcgatatcc gtgatttgat tgcgaacgct acgacggttc agctccagtt
    43741 ggctttcacc aggaccacgg gaaccaattc cccctgcctg acggctgagc ataatcccct
    43801 gaccaaccaa gcgaggcaag aggtatttga gttgggctag gtggacttgg agcttccctt
    43861 catggcttcg agcccgcatg gcaaagatat ccaaaatcaa ctgcatacgg tcaatgacct
    43921 taacaccgag aacttcctct agattgacat tctgccttgg ggtcagacgg ttgttgacga
    43981 tgacagtagt gatttcttct gcatccacca taagcgcaat ctcttccaac ttaccagagc
    44041 cgacgaaggt cttggaatca tatttttcac gtttttgtct gtagctatct acaacgactg
    44101 cccctgccgt tttcgctaaa ctagccaatt cttccatgga gaggtcaaaa ctgtccatac
    44161 cctgcaattc cacaccaatc agcaggactc gctcctcttt tttctccgtt tcaatcatct
    44221 aaaaactcct ctatctggct taaaatgcgg tcttgtacac cagattctcc aatctgataa
    44281 aaggtgacct gcatgcgatt acggaaccag gtcagctgac gcttggcaaa acgacgggtc
    44341 gcctgtttaa gactctcacg agcttcctca aaggtctgct ctccacggaa ataaggaaag
    44401 agttccttat agccaattcc tttagcagcc tgtacattag gggaatggtc aaacagccac
    44461 ttggcctcat ccaaaagccc agcctcaaac atcaaatcca ctcggtggtt gatacgctca
    44521 taaagttgac tacgttcatc atccaagcag ataatcagcg gttcatacaa aatctcttga
    44581 ttttccaaat cctgaccaaa atgggcaatt tctaaggcac gcatagcacg acgacgatta
    44641 aactggggaa tctcaaggcc tgcttgctcc accaaatggg ctaattcctc atctgaatat
    44701 ggctccaaac tagctcgata agctaaaatc tcctcatgag gagtctcccc acctaggtgg
    44761 taaccttcta gcaagctctg gatataaagt ccagtcccac cggcgataat ggctagcttg
    44821 ccacggctgt gaatatcctc aatagtcatc ttagcttctg aaacaaaatc aaaagccgag
    44881 taagactcgg ttatctctct aacatcgatt aaatgatgag gaacagctgc ctgctcttct
    44941 ggactagcct tggccgtccc aatatcaagt cctcgataga cttgttggct atctccacta
    45001 accacttcgc cattaaagca ctttgcaact tcaatagcta gagccgtctt tccaacagca
    45061 gtcggtccaa caatcacaat tatttttgtt ttcatctttt ttccttgaaa aattcccatt
    45121 ttttcgttac tattattata acacaaaaag gtcagtcaga aaaatgtgac ctcttgagga
    45181 ggctggctga ttgagaatat aaaggaggaa gactcatggc taaaggattc gctaaaggtc
    45241 ttgtaacagg tgtcgcagga actgtcgctg ccgttgcagg tgcagtatac gcatttaaaa
    45301 agaaagtaat cgaaccagaa gagcaaaaag cagctttcat cgaagaaaac cgtaaaaaag
    45361 cagctcgtcg ccgcgtatca cgttaagaaa caaaagaagt tgggattatt ctcaacttct
    45421 tttttctatt cttttaaata gctaggtcaa acttcaactg tggcttaaca gggtcataat
    45481 ccaccaactc aaaatcttct gctttgatat caaagaaatt agtcccatca ggaacattta
    45541 aaaccaagcg tggttggcag tttgacggct cccgacggag caattcctga gcttgttcaa
    45601 attgattatc atagatatgg aggttgttga tgaagtagaa gaacttccca accttccagc
    45661 caaaatgttt ggcaatcatc atctgcaaag ccacatactg catagcgttg atgtggtggg
    45721 ccaccagcat atcattggag cgctgggtca aggtcgcatc cagatagatt tccccatcaa
    45781 cacgccggac atcaaacatg gtctgaaagg cgcacgggag cagcccatct gtttcttcga
    45841 aagcttggta atcccagagc gaaataatat tgcggcggtt ccaaggattg gtttccaact
    45901 gtttgagaag cttattgata atgtcgtgtt tcttaacaac ggcaccatag cgctcaccaa
    45961 tggttcccgt gtctccaact tcccagtcat tccagtagtg aacattgtac ttgtcattaa
    46021 gcacttctaa gctatttgac tggtcttggt aaatccagag aacttctttg atggcggatt
    46081 tgattgcaat gggacgcaag gttgtgatag gaaattctcc tttagataag tcgtactcgg
    46141 aaaaggcacc agttacatac ttggaattag caacagtccc atccttgtac ttaggacgag
    46201 cctgctctga gaaaacacct tcctttagaa tgcgttcaat attctcttta aaaatcgtat
    46261 ctgcttttgt catttcgttt cacctcattc attgtcctaa ctagtatagc ataaaaaata
    46321 aaagaggaac attactaact ctaggttagc attttcctct ctcattatct tattgcaata
    46381 caagtgatgc tgctccgata actccagcgt catttcctag agttgcaaga gctaatttag
    46441 tagatgtgcg tacttgtggg aaactatttt catcgtaaac tttttgaaca ccttgtagaa
    46501 ggaattctcc cgcagctgac acaccaccac cgatgacgat tgttgatggg tttaggattg
    46561 aaccaatgtt agcacaagcg attcccaagt aacgtgagaa gttacggtaa acaatcaaag
    46621 caaggtcgtc tccttctttt gcgagatcaa agacagtctt agcagttact tcttctccgt
    46681 tatcaatcaa gcgtttcaag gctgcatcgc cttcgtattc atcggcatag cgacgagtca
    46741 agttgacaat ccctgttgct gaagcaactg tctcaaggca gcctttttta ccacaagtac
    46801 atgagattgg ttggtcaaag tcaacagtga tatgaccaag ttcacctgct gcaccagcaa
    46861 caccatgaag caatttgcct tctgcgacaa taccaccacc aacaccagta ccgagtgtca
    46921 taaagacaac gtctggttgg ttatctccag cacccatcca gcgctcacca agagctgcta
    46981 cgttggcatc attatcgatg aaaaatggaa tgcccaaagc tttttcaatc ttttgtttga
    47041 ttggttgaag ggttttccag ttcaagttgt aggcaccgat aacagtccct ttttcacggt
    47101 caaccacacc tggtgatccc attccaatac cttggaagtc cgctgctgcc aatccaagca
    47161 agtccaaacg atgttgaata gactcaatca tatcatcaac gatatgactt ccctcatcca
    47221 aaatgttggt cttgattgac cattttcctt ggatttctcc tgctgttgtt aagattgcaa
    47281 atttgataga agttccacca aggtcaatcc caataatctt ttgactcatc atattctcct
    47341 ttttcattgt gtagtaattg aaaatgctta cagtactagt atatcaaaat ccattcactt
    47401 atgcaaaggt ttgcgtaaat gaattataag gaattttttc gcctaccagt atctgttaac
    47461 catctaaatg atcaatggca tattgagctg catcatttga aaatttatca aaatcagaag
    47521 ttaattgtct atacatacgt ttttttgaca tgtggaataa cgaattataa ctttttgcct
    47581 ttcctaaagc agcagaatat tcactattgc tatcattact agaagaagct gtacttgctt
    47641 gaccttcctt ccaaactccg tcagcgccaa cataataacg tccaccatca acccattcat
    47701 tgacagccat tttaccatcc gattttagat agtaatttcc ttgccatgta ctgtaagcat
    47761 aagaaccatc tgatgtcaaa taataccaag cttgataaga agagtcataa atccattcac
    47821 tctgtgccat tttaccatca gctttcaggt aatagtttcc ctgccatgca ttttcactag
    47881 atttccattt ccatcaaaat agtaccaaga accgtcctgc ttaacccaac cacttgctgt
    47941 ggatgaagtt gtatcagttt gagttgtagc cgcttgtttt gctttaaaag cacccttagg
    48001 agcatttttc aattcgcaag ccacaccatc atgatcgcgg tctaacttgg cagaataacc
    48061 aggttctccc tcatgaagat ccgaatatcc attagcccaa gcttccttac aactcgaaaa
    48121 atgaatgttt tcctctgcta acacaggttg tgaaaacaag gctaaaattg gcaacgtcac
    48181 cagactcatt tttaaaaata gacgtttatt catttctttc tcccataatt atgatatcga
    48241 tttcaatatt attttatcaa acttatttca gcaattcaag gaaacttctg gtcttttcta
    48301 caaactcctt tggttttgcc ttattcaaga catgagggcc atctgggata atctgaaatt
    48361 gggattctga tattagttta tgaagacttc tcatagaact aagattcggt ttatctttga
    48421 taccacaaat tagtaaggtt ggataagggc aagttcctgc tatatccgtt aaatcaagtg
    48481 tcttcaactc ctcagaaact ccgaccataa gagccttgtc tgctccctgt ttttcaaata
    48541 ctcttttggg aagtagttta aaaatcagca actgaagata aaataggata ttccctgcta
    48601 atttaagcgg gcatcctgac agaatcaaag ctcgaagatt tggtaaatcg taactggaaa
    48661 gttctagtgc cagggcagca cctaaggaca atccaatcaa aacaaaaggt tctgtctctt
    48721 gagctaggtg ctgataaact cgctccttag cttgttgata gttactaact ccagaaggaa
    48781 ataactcgat agcctcagaa ggataatctg tcagtagatt ccgaacttct ttccaagact
    48841 ctgctgactg ccctaaccca tgcaaaaata tcagtttcat ctagttctcc tcaaggctta
    48901 gttcatacaa gcctctcact gcattacagc cgtaaatagc ttctgcttgg gctaaatctg
    48961 ccaaggtcaa gactttctct tctacctgtc ctgtttctag caaatactga cggtaaattc
    49021 ctggcaagat tccaagtcgg ataggcggtg tgtagagttt tccagcgatt ttcagaacca
    49081 aatttcctat agaggtttca agcagttttc ctgacttatt gtggtaaatc ttctcttgtt
    49141 ctcctaggct caaatgcggt cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag
    49201 cagcttcctg aaggcagact tgggcctgac aaaagcttgt actgagaggg gttaatactt
    49261 gacgattgac ttctatctct ccagatttgc taaggctgat tcgcaagcgg taatcttgat
    49321 tagcttcaca atcctgacac tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag
    49381 gaaaggcaaa ataacgacta gcttttctca gtctttccag atgttgatct tcaaacagca
    49441 ggttcttctg gctgatttcc cctgtcgtaa tcagttggaa gcgggcttgt ttacgataaa
    49501 gaactgctgc cttttgatga acctctcggt attcagattc ccatgtgcta tcccaagtaa
    49561 tccctccgcc aactccataa atggcttgac ctttgtgaag ttgaatggta cgaatggcca
    49621 cattaaaaat ccgtcgtcca tttggaagca agagaccaat cgttccacag tagactccac
    49681 gcggttgagg ctccaagtcc ttgataatct ccattgtcgc aattttcggt gcacccgtta
    49741 tggaaccaca aggaaagagt gagcggaaga tttcaacaag gtccacatcc tctcgcaact
    49801 gactcttgat ggtcgaagtc atctgccaaa cagttgaata ctgctctacc tggcacagac
    49861 gctccacgtg ctcgctccca acttcagaaa tacggttcat atcattgcgc aagaggtcca
    49921 caatcatcat attttcagag cgatttttgg gatcctgttc caaccaactg gcctgttcaa
    49981 gatcttcttg gtcagttacc ccacgctgag tcgtcccctt cattggtcgt gttgtcaact
    50041 cgcgatcatt ttgctcaaaa aagagctctg ggctcatgga aatcactgcc atctcgtcat
    50101 gttccacata ggcattgtag cccgcctcct gctctaccac catacgattg tagatggcaa
    50161 aaggattggc acttaacttt tgcttgagtt ggacggtgta gttgacctga taggtgtctc
    50221 cctgcctcaa gtgatggtgt atctgggcaa tggccttttc atagtctgct gcagacgtca
    50281 cttcctgcca atttgagggc aaatcaatat cctcataagt cagaggaata ggggaggtct
    50341 ctaccctatc atgaacagta aagtaaagca ggtactctcc cagtagggga tccttgtgaa
    50401 ctgctaattt ttcctcaaaa gcaggggcag cctcgtagct gacatacccc accacataat
    50461 aaccttgctc ttggtagctt tccacttgtg ccagcaaatc tgccacttct gctacatttc
    50521 tcgtttttat ctctttgata ggctgggtaa aggtgtatct ctcccccaaa atcctaaaat
    50581 caatcactgt ttttctatgc ataccttaag tatagcataa aataagaaaa ccctcatccg
    50641 caaagcagat gagagatttc aattatttaa agattgaagt tttaaagcta tttgtttgtt
    50701 gaagaagttt cttataaact ttttctttta cttgcacaag tttaccatta actttattag
    50761 taaccatatc ttcttcaaga gctttggcaa ataatgattt taattcatca tagttatgaa
    50821 tggtctcacc atcaatagta aaaggagtaa aaccagcgtt ggctttttct aacaattctt
    50881 tataatattc tttcttaaaa tcagcaaacg attggaatct gccgtcagat attttttgta
    50941 taatatattg atctccaaat tgtttccctt ctttattagc ttgagatttt aatttatctg
    51001 aagcatatcc taagaatcct ttatcatagc cataatatcc ccagagtcta aatgcattat
    51061 tcttaaatgt aacagcaccg ggtgcaccct cacttgtgtt acctgcatag atactattca
    51121 tcattttaat tcctacatag gcaatacctg gatcaaatac ttctggctta tatatattat
    51181 tattcatcat acgattagtc atcagattat tatcaactaa gtcattaaca ctgtttaatg
    51241 ttattccttt ccaatcatca gagctcatat ttcgaacctt gtcatattga tcttttgacc
    51301 ctacagtgcg ttcaatagga tcaactttct taaaccacag ttgatttaat ttatcatcat
    51361 gtttactaat gactgcatca ccttcaacat aatcaagaag agacaaggta tctatatagc
    51421 ctttcatata attatcaatg tcttctcttg ttttaagagt cttcggatcg gtaatatacc
    51481 actgatttcc atcatttgga cgatagaaag tcatattaat tcccaaagca ccgtattcat
    51541 caaaccatgt acttggtact ggtgtttgta acattccttg tgcataggct tctgcatgag
    51601 tccctgagcg acgtccatat cctcctaaat agattgcacg atcattaaca tgagtagttt
    51661 catgtgtata aacagagatt ccaaactcat caatcatact taatgcaata taatttactt
    51721 ctgttcgcgt atccaaagga ttatcccaaa taactgcata agcacctgtt ccattgttac
    51781 cataatactt accaataggt ccaaacaact ctctcaatgg ggcatagtct tctttattat
    51841 ttctcttacc atacttatca ggccatccac caggtgcttg ataaccttcc caaagaggag
    51901 ttactgtatt tttgactagc atattcttaa ccttatctaa agataatcta taccaaaaat
    51961 caaaataatt tcgataactg tccgctgctt tttcaatctg attttttatt ccatcgaagg
    52021 agctatgccc taacttttct gctgttccaa cagccattgc actataattc gagattaaat
    52081 acacatgtga tttatttaga tttaataatg ggagtatcat cttccgatga gtagcagatt
    52141 gtaaattatc ccaaacttta tatttcgccg ctttaatttc atcgacttcc gaagcacgct
    52201 ccgctatata gacattccct tctgtagctt tcttaaacca atcataaata tttacatctg
    52261 cagtaaatag tcgacgatta taatttaaaa agtttaccaa attttctgat aaggttgtct
    52321 tagaaataat ctcgctgaaa gcatcatatg tccgatgacc ttttatatta tcttctcttg
    52381 aaccgatttc aattaatcta tctaatacac ttacattttt accatagaaa tctggtttga
    52441 ataacattaa ttctttaatg ttaacatcac cgaatttaac accgtagtaa cggtttaagt
    52501 atgttaaacc taataatagg gcagctttat ttttctcaac tttatcaaga atcatttgtt
    52561 gagctgcaga tgaattattc agttgatgat cttcattttc aactaattta gttactaata
    52621 tgtttaaatt agcttttaca tggtcaaaac tttcttctaa ataaaggtct ttaattgcat
    52681 ttactctatt agaccctgtt ctgccaagtt tttggtaaat tggattagat tgaagctcaa
    52741 tagggcttaa gatatttacg ataccgttaa ttaaagcact atgatctttt tgaacgatat
    52801 taggtgtata tttaatacct aagtcagtta tagtgtattc tctaacatta cttagacctt
    52861 catcactaga agataggttg aagtagtctt ttgttccatc agcataatga acgataattt
    52921 tgtttgcatc acctaaatca gttacaaagt tattattgtt cataggagta accgatagaa
    52981 tctctttagt atttaacttg ttgttcttat ctagtttatt agcttgatta acgataaaat
    53041 ctttgttata gaatggttgt agtttttcaa tattcttata agcaagttta tagtctgcat
    53101 tataatcttg aatagactcg taagctgctt cacgactgct aacattattc aatttgttca
    53161 attcataagg ttcacttacg aatttagcag cagtaatatt gaaactagca acttttgcat
    53221 cagcctcaga tttagataag tgttttaatt tatttttgtt tttattatct ttaccagttc
    53281 catcttcaga agagctatat ccaataactc caaataaatt agacacaaaa ggatttgcat
    53341 ctccatcatt aacatcgttt gaaccgaata tttcctgacc tttaataact ttcgcatatg
    53401 ttacattatc ttgaaccgct ccatatggcc aagttttaga ggttattcca ccaacatatt
    53461 tagtattttt aacatcaaga ataccttttg ctacagagtt tgtaagtttt ccttttgtcc
    53521 ctgatagcca gctatgagct ttatattgaa cgaaaggaac aagcatactt gcatttgcgt
    53581 tatttgctgt aatagtagca tcaacgtagg ctctattaac aaaccccata tagttagaac
    53641 cggcaatacc tccaactgtt gaattattac cagcagaatt tatactaccg ataaatgcca
    53701 cattttctaa agtagcgtct tcttttatgt tatttacgaa cccagcaaca ttatttctag
    53761 ctgttatggt tccgattgct ttgatatttt ctatacgtgt cgttccactg atttcatttg
    53821 ctattgcagc gatattatct tgattagata aatcaatatc aatattttca aaatttatat
    53881 ttttaacagt tccagcctta atcttatcga ataaaggatg ttccaaatta tggatagcat
    53941 agcgtttatc accatcactc aatagtttac cagtaaactc tgaagtaata taagatttcc
    54001 ctttaggaac aacgttacga gcgctcatgc tttgacccag tttaaattca ccggcaggat
    54061 ttgtctgaat ggcttggatc aattcttcaa agtcgtagaa aataccagcc tgactagctt
    54121 tgggtttttc aatatagtag gtataagttt cttcaaagcg attatcgaca ttacgttgga
    54181 ccaagttatc cgctactgct attaccttgt agacttgttt tccatcaatt gttgactctt
    54241 caattttttg aaccgctagt agattggtct tatggtcatt agaggtaact tttaaataat
    54301 aatttgacaa atcagttggc actgaagtca atcgagtttc atcagtttca acttggtttt
    54361 catatttgat taaatccgtt cttataatat cttttatttc aacttttttg agatcaattc
    54421 ttagcggttc ttctttcaga acttcttcct catccccctc accacggtca taaaccatct
    54481 ttgtttcaag tttataatcc ttgtagtact gcaaatctgt cagggtagtt gtcaagtctt
    54541 ctggtgaaac attcaaggtt ttgacaatct catcaccttt tttcagagtt agggtaatag
    54601 atttaatggc tgccttactt ggattttcta aactatactt aacatctgaa gtacgcttca
    54661 aatccttaga ttcaatttct gtgatggtca acactggttt ttcaaagctc ttggtaccac
    54721 gtttcaaaat tttgtcttga ggttcctcaa ggatttcctc tgtaactttt ggagcgtctt
    54781 ctgttttaac tcccttaatg gtattaaagg tcttggtgat ttttttctgg ccttcttttc
    54841 cttcttgagc tacaacttct aagccttttt tcagttggtc atcttcttta acaacttcct
    54901 taaatggaat cttttcaaga ctttcttcta taagagttcc ttcaattggt tttgtaccac
    54961 ggattacctg ttgatttaca ggctccttgg tcacttccgt actggttgaa agaacttggt
    55021 cagttttaac accttctact gttttatagg ttgtttttgt aacttgactt cctttttcac
    55081 cagttcgtag gacagtttct tcgtccgtat acttggttgg atcctcagtc gtttcagttt
    55141 tgtagtctag gtctgtagtc gatgtttcaa caagggttcc ctcagttact ttgtactcag
    55201 gtaattgttc ttgagcaaga gcctcaccca cgtgaccttt ttcttgcgta cctttagctg
    55261 ttttagtctc ctcttttgat tctactggtt cttcaacctt gatttctggg gcttctgctg
    55321 gctgttcatc ttcttgtttc ggtgtctctt ccgctcccct atcttcttta ggattttctt
    55381 gttgtgatga ttcttttggt gtacttggtt gctcagcttg tgtaggttgc acgggttgtt
    55441 ctgggacttt tgcttgttct actggtggtt caacttttga ttcctcagct ggtttgtctg
    55501 atggttgact ttctggctta actgctactt tttcctctgg ttttgactca acttctccac
    55561 ctacttcttc aactggagct ggttctgctg aatcttcttt cccctcttct actttaggaa
    55621 gggtgtcgtc agtaggtttt acctccgatt ttggttcttc ctttggactt tcttctgttt
    55681 taggtgcttc ttcttttgga gcttcctctg tctctactac ttggttttct gtcctagctt
    55741 gctcctgatt tgttgttgat tgaggagtct caacttcgac tacagtcacc tctccaggtt
    55801 ttgctgaggt ttcttctaaa acagtgtcca agccaagcgt tttgaggatg tcacctgata
    55861 gataaccaac atagcgatag ccatccattt caacaacacc ctctcgacta gccagcgcta
    55921 gggtcgcaac tgggtctaca gcccctgcac taggaagaac taccaatccc atagctccaa
    55981 ctagaaagac gctagcaatt ttctttctct tgtagattaa aagcaagctc ccaacagtca
    56041 gcaaaccaaa agctgtcaaa acagatgctt ctgtccctgt ttgaggaaac tgatcttttt
    56101 gatacaccaa accatataca acttcattcc tgtcaggctt tcctgtctga attaaatctt
    56161 tagcttcttg tgaaataatc tctttattta catagtgata ggtggctgcg tccactacag
    56221 aaggagccat caaaaggctt ccaagaaata cagagcctac aactccctta atcttacgaa
    56281 ttgaaaaacg gtctttttta aacactttta tctcctttat tcattctcaa gactttctaa
    56341 tagcatcttg cggatagtgc gcacgcgcac ctccgattaa ttttggacga ctagccagtg
    56401 ccgttacatg ggcatgacca atctctctca aaatagggcg aatcggaacc tgaacatgct
    56461 tgacatgcat gccaattgca gtgtctccga tatccaatcc agcatgagcc ttgataaatt
    56521 caacctcaac tggatcctgc ataaacttaa aggctgccaa ctgccccgaa cctcctgcat
    56581 gaagagtagg atggacactg acaatttcca gatcaaactg ctctgccacc tgacgttcaa
    56641 caacgagagc ccgattgaca tgctcacaac cttgaactgc taaatggata cctctactac
    56701 ctagaatacc caagatagtc tccactatca gctcaccaat ctcttgactg gattctttcc
    56761 caatctgacc acctagcacc tcactagaag atagacctaa aacaaaaagg accccctgct
    56821 tcaaattggt cttttctaaa acatcttcca ctacctgacg tgtttctctt tgaatctgtg
    56881 tctcgttcat ctctgttacc tctgttgtta ctcttctatc ataccgtttt ttcttgtttt
    56941 tagcaagata gacaacctag aaagcttgcc caattacgca taaaactccc agaattgact
    57001 gggagttagc tagtttctat tctatttata tatatttcaa ctttcgtccc tttttggggt
    57061 ctagaatcaa tcttcatctg gtaattggct ccaaaatgaa gtttgagccg ttgatcgaca
    57121 ttttgaagac caactccccc acgtttgagt tgactttgac tactatcacc agcatcttgg
    57181 aagccaacgc catcatcctc aatacggatg accaatcccg aatcctgttt ctggacagaa
    57241 agtttaatat ggccctgacc ttccttttcc ttaatgccat ggtaaagagc attttctaca
    57301 aggggttgta ggaccagctt gggtaagact aaattatcaa aggcaacatt ttcattaatt
    57361 tcgtattcca gcttatctcc atagcgttgt ttctggataa agagatactg gcggacatga
    57421 ttgatttcgt cagagagaca aatcaagtct ttgccttgat tgagcgccaa gcggaaatag
    57481 gttgccaagg acttggtcac ctgcaccact cgctgactat catgaaattc agccatccag
    57541 atgatggtgt ccaaagtgtt atagaggaaa tgtggattaa tctggctcga aagggcttga
    57601 agttggtact gacgggtcgt ttcttcctgg ctacgaatag ctaccatcaa ctgatcaatc
    57661 tgatccaaca tggcattaaa ttggcgagtt acttctctca gttcataggc accaacttcc
    57721 ttggcacgaa gattttgagc accagaagca atttccaaca tggtttctct caaatccttc
    57781 aaaggagcaa tccagcgttt aagactgaac cacactaagc agagacaaac aagaagagat
    57841 gtgacactgg ccccaagcaa ggtccacaag agctgactcc gaacctggtc taacttttcc
    57901 aatgatgaca cgccaagtac cgtccaatca gttcctgcaa tcttctcttg actgacgtag
    57961 gatttgtgac caggagtata accctgacct gtctcgatgt agggtttcat agcctccatt
    58021 ttgctagacg aactataaac tgtgtgttga ggatggtaga caaattcatg gttttcattg
    58081 ataatgaagg caaagccctg ctgccccaac tggagttgat tgagataggc ttccagagtt
    58141 tcataagaaa tatccaaacg aagcacacca agattggctc cctttgcatc aacaagttct
    58201 tgagtgacag aaatgaccca ctgactatct gatttacgag ctggagtcaa aacaggcata
    58261 gctccctgat gaatagcctt ttggtaccaa tcctcagcca tcatatcaga ggaagttttc
    58321 atctgcacac tgtcatctgt agaaatgacc tgaccagatt tggtcaccag cacaacagtt
    58381 ttcaagtcct tatctgactt caagatggtc aaaaacaaat ctcggattcc ctcgaccttg
    58441 tcttgactgg gattctcagc ataggccaga acatccgtct gctgggtcaa accagtcgag
    58501 gtggtttcta gttttttgat ataagactga ataaagtggc tagtctggct gatggtcgtt
    58561 tggctgttgc cctcaatggt ggcctcaatg gctgaagaac ttgattgata gtagaaagtt
    58621 ccaaccagag ctaggagaat gagaaagacc agaaagatgg aaataaccat tctaactaaa
    58681 agagaagaac gcttcatcgg tcttctccct tcttaaactg acgaggtgtc acacctgcaa
    58741 tctgcttaaa acgttgggta aaatagttca tatcttcaaa accaaccttc tctgcgatct
    58801 cataaatctt cagatctgta gttaaaagca agagcttggc ttgtttaaca cgttctctca
    58861 ccagataatc ctgaaaaggc aagcccaact ctttcttaat caaggaactc agataggtcg
    58921 gactaaaacc taagtcactg gctaaagact ttaaactaaa ttggctatca gccagatgag
    58981 actggatttt ctgggccatg tttccttcaa acctattagt caataaatct tgtaactgct
    59041 cttctttctc ttccttgtct agtttttgtt tgattttccc caacatttcc tcaatatcct
    59101 gacgagaaaa gggtttgagc aggtagtcgt ccacacctag tttgacagca gacaaggcat
    59161 aatcaaaatc atcgtaacct gttaaaaaga ccaaatgaac ctgaggatag gtttctcgta
    59221 ccagactggc caactggatg ccatttagat gaggcatgtt gatatcggtt aaaatgatat
    59281 ctggcacctg cttttggatc aattcccaag cctgccttcc attttcagcc tgaccgatga
    59341 tttccatatc gtaggctgct acattgacca gtttagtcaa accttgtctt accagatatt
    59401 catcttctac gattaagatt gtgtaggtca tgctctgctc ctttaccact tactagtatc
    59461 agtatagcaa aattctcctc taactgctta ggaaagacct cttatactca ataaaaatca
    59521 aaaagtaaac taggaagata gccacaggtt tctcaaagta tagctttgag gttgta
//
LOCUS       DAVBOH010000009        49378 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOH010000009 DAVBOH010000000
VERSION     DAVBOH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.009"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ873_000547"
     CDS             complement(93..551)
                     /locus_tag="VQ873_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3106867.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ873_000548"
     CDS             complement(548..988)
                     /locus_tag="VQ873_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3106868.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ873_000549"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ873_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3106869.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ873_000550"
     CDS             complement(3468..3935)
                     /locus_tag="VQ873_000550"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3106870.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ873_000551"
     CDS             complement(3936..5141)
                     /locus_tag="VQ873_000551"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3106871.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ873_000552"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ873_000552"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3106872.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ873_000553"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ873_000553"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3106873.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ873_000554"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ873_000554"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3106874.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ873_000555"
     CDS             7889..8452
                     /locus_tag="VQ873_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3106875.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ873_000556"
     CDS             8449..9126
                     /locus_tag="VQ873_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3106876.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ873_000557"
     CDS             complement(9263..10294)
                     /locus_tag="VQ873_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3106877.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ873_000558"
     CDS             complement(10549..11232)
                     /locus_tag="VQ873_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3106878.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ873_000559"
     CDS             complement(11244..12188)
                     /locus_tag="VQ873_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3106879.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ873_000560"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ873_000560"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3106880.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ873_000561"
     CDS             15144..16205
                     /locus_tag="VQ873_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3106881.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ873_000562"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ873_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3106882.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ873_000563"
     CDS             16801..17370
                     /locus_tag="VQ873_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3106883.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ873_000564"
     CDS             17457..17723
                     /locus_tag="VQ873_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3106884.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ873_000565"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ873_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3106885.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ873_000566"
     CDS             18162..18467
                     /locus_tag="VQ873_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3106886.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ873_000567"
     CDS             18773..20023
                     /locus_tag="VQ873_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3106887.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ873_000568"
     CDS             20020..20562
                     /locus_tag="VQ873_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3106888.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ873_000569"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ873_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3106889.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22498..24036
                     /locus_tag="VQ873_000570"
     CDS             22498..24036
                     /locus_tag="VQ873_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3106890.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ873_000571"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ873_000571"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3106891.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ873_000572"
     CDS             26375..26515
                     /locus_tag="VQ873_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106892.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ873_000573"
     CDS             26559..27065
                     /locus_tag="VQ873_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106893.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ873_000574"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ873_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3106894.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ873_000575"
     CDS             27645..28262
                     /locus_tag="VQ873_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3106895.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ873_000576"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ873_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3106896.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ873_000577"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ873_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3106897.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ873_000578"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ873_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3106898.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ873_000579"
     CDS             30316..30612
                     /locus_tag="VQ873_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3106899.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ873_000580"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ873_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3106900.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ873_000581"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ873_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3106901.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ873_000582"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ873_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3106902.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ873_000583"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ873_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3106903.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ873_000584"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ873_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3106904.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ873_000585"
     CDS             33297..33503
                     /locus_tag="VQ873_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3106905.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ873_000586"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ873_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3106906.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ873_000587"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ873_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3106907.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ873_000588"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ873_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3106908.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ873_000589"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ873_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3106909.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ873_000590"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ873_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3106910.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ873_000591"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ873_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3106911.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ873_000592"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ873_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3106912.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ873_000593"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ873_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3106913.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ873_000594"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ873_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3106914.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ873_000595"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ873_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3106915.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ873_000596"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ873_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3106916.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ873_000597"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ873_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3106917.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ873_000598"
     CDS             40036..40674
                     /locus_tag="VQ873_000598"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3106918.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ873_000599"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ873_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3106919.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ873_000600"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ873_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3106920.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ873_000601"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ873_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3106921.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ873_000602"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ873_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3106922.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ873_000603"
     CDS             41977..42912
                     /locus_tag="VQ873_000603"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3106923.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ873_000604"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ873_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3106924.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ873_000605"
     CDS             43575..43841
                     /locus_tag="VQ873_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3106925.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ873_000606"
     CDS             43851..45188
                     /locus_tag="VQ873_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3106926.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ873_000607"
     CDS             45432..46124
                     /locus_tag="VQ873_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3106927.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ873_000608"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ873_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47862..48485)
                     /locus_tag="VQ873_000609"
     CDS             complement(47862..48485)
                     /locus_tag="VQ873_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3106928.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48471..48593)
                     /locus_tag="VQ873_000610"
                     /pseudo
     CDS             complement(48471..48593)
                     /locus_tag="VQ873_000610"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48570..48940)
                     /locus_tag="VQ873_000611"
                     /pseudo
     CDS             complement(48570..48940)
                     /locus_tag="VQ873_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..49321)
                     /locus_tag="VQ873_000612"
     CDS             complement(48953..49321)
                     /locus_tag="VQ873_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3106929.1"
                     /translation="MTVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
BASE COUNT        14870 a         9322 c        10872 g        14314 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ttaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagta
//
LOCUS       DAVBOH010000010        48258 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOH010000010 DAVBOH010000000
VERSION     DAVBOH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.010"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..87)
                     /locus_tag="VQ873_000613"
     CDS             complement(<1..87)
                     /locus_tag="VQ873_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3106930.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEML"
     gene            complement(95..535)
                     /locus_tag="VQ873_000614"
     CDS             complement(95..535)
                     /locus_tag="VQ873_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3106931.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEITAETRQAKPDEIRLPAKQNMV"
     gene            complement(537..1574)
                     /locus_tag="VQ873_000615"
     CDS             complement(537..1574)
                     /locus_tag="VQ873_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3106932.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1672..2997)
                     /gene="brnQ"
                     /locus_tag="VQ873_000616"
     CDS             complement(1672..2997)
                     /gene="brnQ"
                     /locus_tag="VQ873_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3106933.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3168..3260)
                     /locus_tag="VQ873_000617"
     CDS             complement(3168..3260)
                     /locus_tag="VQ873_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3106934.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3303..3455)
                     /locus_tag="VQ873_000618"
     CDS             complement(3303..3455)
                     /locus_tag="VQ873_000618"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3106935.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3615..4193)
                     /locus_tag="VQ873_000619"
     CDS             complement(3615..4193)
                     /locus_tag="VQ873_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3106936.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4247..5647)
                     /gene="pepV"
                     /locus_tag="VQ873_000620"
     CDS             complement(4247..5647)
                     /gene="pepV"
                     /locus_tag="VQ873_000620"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3106937.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5660..6265)
                     /locus_tag="VQ873_000621"
     CDS             complement(5660..6265)
                     /locus_tag="VQ873_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3106938.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6436..7236
                     /locus_tag="VQ873_000622"
     CDS             6436..7236
                     /locus_tag="VQ873_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3106939.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7418..8215)
                     /locus_tag="VQ873_000623"
     CDS             complement(7418..8215)
                     /locus_tag="VQ873_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3106940.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8205..10049)
                     /gene="uvrC"
                     /locus_tag="VQ873_000624"
     CDS             complement(8205..10049)
                     /gene="uvrC"
                     /locus_tag="VQ873_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3106941.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10089..10790)
                     /locus_tag="VQ873_000625"
     CDS             complement(10089..10790)
                     /locus_tag="VQ873_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3106942.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(10869..12101)
                     /gene="murN"
                     /locus_tag="VQ873_000626"
     CDS             complement(10869..12101)
                     /gene="murN"
                     /locus_tag="VQ873_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3106943.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12106..13326)
                     /gene="murM"
                     /locus_tag="VQ873_000627"
     CDS             complement(12106..13326)
                     /gene="murM"
                     /locus_tag="VQ873_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3106944.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13438..14217)
                     /locus_tag="VQ873_000628"
     CDS             complement(13438..14217)
                     /locus_tag="VQ873_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3106945.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14286..15947)
                     /locus_tag="VQ873_000629"
     CDS             complement(14286..15947)
                     /locus_tag="VQ873_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3106946.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16122..18344)
                     /gene="recJ"
                     /locus_tag="VQ873_000630"
     CDS             complement(16122..18344)
                     /gene="recJ"
                     /locus_tag="VQ873_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3106947.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18621..19379
                     /locus_tag="VQ873_000631"
     CDS             18621..19379
                     /locus_tag="VQ873_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3106948.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            19390..20184
                     /locus_tag="VQ873_000632"
     CDS             19390..20184
                     /locus_tag="VQ873_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3106949.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20197..20874
                     /locus_tag="VQ873_000633"
     CDS             20197..20874
                     /locus_tag="VQ873_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3106950.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20884..21543
                     /locus_tag="VQ873_000634"
     CDS             20884..21543
                     /locus_tag="VQ873_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3106951.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21780..22904
                     /locus_tag="VQ873_000635"
     CDS             21780..22904
                     /locus_tag="VQ873_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3106952.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(23302..24183)
                     /locus_tag="VQ873_000636"
     CDS             complement(23302..24183)
                     /locus_tag="VQ873_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3106953.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24324..25652)
                     /gene="vncS"
                     /locus_tag="VQ873_000637"
     CDS             complement(24324..25652)
                     /gene="vncS"
                     /locus_tag="VQ873_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3106954.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25649..26305)
                     /gene="vncR"
                     /locus_tag="VQ873_000638"
     CDS             complement(25649..26305)
                     /gene="vncR"
                     /locus_tag="VQ873_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3106955.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26354..26437)
                     /gene="pep27"
                     /locus_tag="VQ873_000639"
     CDS             complement(26354..26437)
                     /gene="pep27"
                     /locus_tag="VQ873_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3106956.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(26618..27997)
                     /gene="vex3"
                     /locus_tag="VQ873_000640"
     CDS             complement(26618..27997)
                     /gene="vex3"
                     /locus_tag="VQ873_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3106957.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28049..28696)
                     /gene="vex2"
                     /locus_tag="VQ873_000641"
     CDS             complement(28049..28696)
                     /gene="vex2"
                     /locus_tag="VQ873_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3106958.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28709..29986)
                     /locus_tag="VQ873_000642"
     CDS             complement(28709..29986)
                     /locus_tag="VQ873_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3106959.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30342..30512)
                     /locus_tag="VQ873_000643"
                     /pseudo
     CDS             complement(30342..30512)
                     /locus_tag="VQ873_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(30820..31254)
                     /locus_tag="VQ873_000644"
                     /pseudo
     CDS             complement(30820..31254)
                     /locus_tag="VQ873_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31391..32275)
                     /locus_tag="VQ873_000645"
     CDS             complement(31391..32275)
                     /locus_tag="VQ873_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3106960.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(32279..32665)
                     /locus_tag="VQ873_000646"
     CDS             complement(32279..32665)
                     /locus_tag="VQ873_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3106961.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(32658..34001)
                     /locus_tag="VQ873_000647"
     CDS             complement(32658..34001)
                     /locus_tag="VQ873_000647"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3106962.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(34083..34967)
                     /locus_tag="VQ873_000648"
     CDS             complement(34083..34967)
                     /locus_tag="VQ873_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106963.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(34979..35596)
                     /gene="cysE"
                     /locus_tag="VQ873_000649"
     CDS             complement(34979..35596)
                     /gene="cysE"
                     /locus_tag="VQ873_000649"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3106964.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(35612..37825)
                     /gene="pnp"
                     /locus_tag="VQ873_000650"
     CDS             complement(35612..37825)
                     /gene="pnp"
                     /locus_tag="VQ873_000650"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3106965.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(38384..39250)
                     /gene="metF"
                     /locus_tag="VQ873_000651"
     CDS             complement(38384..39250)
                     /gene="metF"
                     /locus_tag="VQ873_000651"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3106966.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(39314..41563)
                     /gene="metE"
                     /locus_tag="VQ873_000652"
     CDS             complement(39314..41563)
                     /gene="metE"
                     /locus_tag="VQ873_000652"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3106967.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(41823..42089)
                     /locus_tag="VQ873_000653"
     CDS             complement(41823..42089)
                     /locus_tag="VQ873_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3106968.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            complement(42215..42662)
                     /locus_tag="VQ873_000654"
                     /pseudo
     CDS             complement(42215..42662)
                     /locus_tag="VQ873_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            42818..43819
                     /locus_tag="VQ873_000655"
     CDS             42818..43819
                     /locus_tag="VQ873_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3106969.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(43887..46289)
                     /locus_tag="VQ873_000656"
     CDS             complement(43887..46289)
                     /locus_tag="VQ873_000656"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3106970.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(46366..46875)
                     /locus_tag="VQ873_000657"
     CDS             complement(46366..46875)
                     /locus_tag="VQ873_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3106971.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(46875..47921)
                     /gene="pheS"
                     /locus_tag="VQ873_000658"
     CDS             complement(46875..47921)
                     /gene="pheS"
                     /locus_tag="VQ873_000658"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3106972.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        13694 a        11044 c         9069 g        14451 t
ORIGIN      
        1 taacatctct tcaaaagtgg tacgctgaac accaacaaga cgcttaaatc gtgcatcagt
       61 tagttgttta cttgcttcat cattcataga actactatac catattttgt ttcgcaggaa
      121 gtctgatctc atccggtttt gcttgacggg tttctgcggt tatttcttca aaagggaccc
      181 accagactgg cccacgtcca ttgagaccgt gaccattcat gtcacctgtt cgtctaggaa
      241 acagatgcca atgaagatgg gcatcgccat ttcctagcag ttcgatattc attttctcag
      301 cagcaaaggc cttggcaact gcctcttgga ccacactcat ttcttctaga aaacggagtc
      361 ttgtctcctt tttcaaatgg tgcaattccg tgacatgttc cttggctaga aagagactat
      421 agcctgcaaa atactgatgg tctccaatca caagatagcc tgtttccaac tctttgacaa
      481 agtagggatt ttctcccttc ttgatgagct caattctctg gcaaataagg cacatatcaa
      541 tctactaaat tgcttctaag ataggcatcg accattcgtt ctgttgcgac caccgagtca
      601 atatgagtgc gctcataaga atgactagac tcgatacccg caccaagaag ggcatgcttg
      661 acctctgccc ctgcagacat agccgctgaa gcatccgaac cataaaatgg atagatgtcc
      721 agcttaaaag gaatatcttg ctctttagcc aaggcaacca agtgttgacg gaagtcatag
      781 tgataaggac ctgaagcatc cttgacacag atagatactg tgtactcatc tgtctgctgg
      841 tcatctccca tagctcccat atccacagcc agatattcta ctacctgagc aggaatgtta
      901 gaattagcac catgtcctac ttcttcaaaa actgaaaaag caaaatgagt tgttactggc
      961 aattcaatct tctctttctt ataaatacga agcaggttga gcaaaatcgc tgcgctgacc
     1021 ttatcatcca aatgacgaga cttgataaaa cctgtatcag tcacaacagt tcgtggatcg
     1081 aagctgataa aatcaccgac ctcaatccca agagcacgag tttctttttc attgcttact
     1141 tttacatcca aacgcacttc catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg
     1201 tagacatggc aagaagtttg gtggatgagg atggttcctg ataccttttg acctgtgcta
     1261 gccacatgaa cggtacagtt ttcaccttca atcatgttcc aaggaaaacc accgatacgg
     1321 tccaatttaa gacgaccatc tggtttgaca gcacgaacaa tagcacccag cgtgtccaca
     1381 tgggcagtca catagcgatg ttgctcatca ttttgacctt tgatggtcac attgacacca
     1441 cccttggctg tgcgaactgg ctggtaacca aaaccttcta gagtcttgac taaataattc
     1501 gaaatttcac gagttaagcc cgttggcgat gcgatggctg tcagttcttt gatatattct
     1561 actgtttgat tcatttcttc acctctttcg ctacctatta taacacattt atcatcggat
     1621 aaaaaaagaa aatcactcct gtagacttgg ctacaaaagt gatttaagtg attattccat
     1681 ttcaaaaaca tcgctttctt gcttgtttgg tagaaccaat gagagcaaga ttccaacaat
     1741 ggctggcacc aaccatggga gagatgcctt ggcaaaagga agaacgctaa caagatttgc
     1801 aagaaactca accttaaacg agcttcctag tacgcttgca atggcaataa ctgtaaccac
     1861 agcaattgtc aactgcatac ctggttttga aagggcaaca aatttgttga caatgacaat
     1921 cataacgata gcaatcgtga ttgggtacaa gataaccagt actggaattg agtacttgat
     1981 aatcgcatca agacccaaat tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata
     2041 aaccttgtag ctgatttgtg ggaagcgctc attaaagaac tcagctgttg acacaatcaa
     2101 accaacagtc gttgtgaagc aggttacggt aaccatagct gcaaggaaga gttgagctgt
     2161 tgagccaaag atttcttgag tggcttgtga caagatgtaa acacctggtg ttccaccctt
     2221 catcgcttca gctggtactg ggaaatgatt tccaagaaaa cctaaaccaa tgtaaagagc
     2281 gctgaaggca agggcaacaa cgataccaat aacccaaata gttgaaatgt attctttctt
     2341 acttgaaaat ccaagttgtt tcaaggtttg aactgcgatt acgctaaagg ccactgaggc
     2401 aagggcgtcc aaggtattgt aaccttctag gaaacctgta ccaaaggcag aagcttgata
     2461 agcagctgaa gcagcttgag gacttgttcc accatatttg atagctccca gaacgaccaa
     2521 gataacaatc aaaattgcaa agactggcgt taaaatacgt ccaatgcggt ctaagatttt
     2581 tgatggatta agcgaaatca aataggctgc cgcaaaatac agaaccgtaa atacaatcaa
     2641 gccaagtcct ttatttgcat ccgacaaaag ggggctaatc cctacttcgt aagctgttgt
     2701 agcagtacgt ggggtagcaa agaatggacc gattgacaag taaagaactg agaggtaaag
     2761 agtcgcaaac caaggcgcta tcttcgttga aatctcgtag atatatcctt taggatttag
     2821 cgttccaata ataagggtca agacggcgat accaacgcct gaaaagacaa aacctgcgat
     2881 ggcaggaaga aaatgttctc cagatagagc acctagagaa ggcggaaaaa tcaagttccc
     2941 cgcaccaaaa aatattccaa acaggagcaa acctgttagg gtaccttttt tagccataaa
     3001 aatctccttc atatttataa aatactgacc tagtatacca cgattaggag tctgaaaaaa
     3061 gcatcacgag gcaaatatta aatgttttca attttcttaa aaataagaat tatctaaaaa
     3121 taaaactctc ctacccagtc cacaccaagt aggagaaatg caaaatttta aagttcttca
     3181 aaggctaaca tgccaccctg gacattgata acattataac cttgttctaa caggaattgg
     3241 caagcacgcg ccgatctcat tccagatttg caaataatat aatgcaagcg atctttgtcc
     3301 aattaatcat aactatcagc caattgacta agcggtaggt tgtgggcaca ttctaaatga
     3361 agagctgcaa actcatccac ttctctcaca tccactagag aaagctggtc gttttggtaa
     3421 agctggtaaa atgcgtcaaa ggctatttct ttcattcttt ttcttctaat actcttcgaa
     3481 aatctcttca aaccacgtca gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt
     3541 ttatctgcaa cctcaaagct gtactttgag cagcctacga ctagcttcct agtttgctct
     3601 ttgattttca ttgactataa aatggtttta attctttttt tcaaatctgg cactacttct
     3661 gcctcaaacc aaggattttt ggccatccag atttgatttc gtggtgatgg gtgaactagc
     3721 ggaaaatagg ctggcagata gtctttatag tgtttcaccc tctccgttac cttcccactg
     3781 attttctcct gtaaatagta ggcttgggca tattgcccaa tcaagagggt taactgaata
     3841 tcaggcaatt cctgtaagag ctgcggatgc catttttctg caaaacctgt acgaggcgga
     3901 agatcacccg acttgccatg tcctggaaag tagaaatcca taggcaaaac agcaaaataa
     3961 cctgaattgt aaaaggtatc ttcatccaca cctagccagt cccgcaagcg gtcaccactt
     4021 ttatctttcc agtaaaggcc tgcttcttga gttttaagtc ccggagcctg accgatgata
     4081 ttgatgcgag cagtttttgg cgctgcaaag agaggctcaa tgccacgctc tgtatagctg
     4141 gcattctgtg aatccgccat gatagcctgt ttgattcttt cgatttgaga catctacttt
     4201 ccctccaaaa agaagtccaa gcataagatc tcagacttct atcgttttat ttgatcaatt
     4261 cgtaaatagc ttcggcataa attgctgctg ctcggaaaag atcatccaag gcgataaatt
     4321 cattggcttg gtgcatggta tcaatcgagt ctgggaacat agcaccgtag gcaactccgc
     4381 gttctagcaa gcgaccaaag gttccaccac cgatgacttg ttcatgacct ttaaggccag
     4441 tttgtttttc atagatattc aacaaggttt gcacaagtgg atcttccatt ggcacatagt
     4501 gaggcgtgtg accgtgttca gacaggctaa cagaaacaac tggcaagttt tcaaggattg
     4561 acttgatttg ttctggactt gttccttttg gatagcggat gttgagggca atggtattat
     4621 cagcacttgt ttcatcgaag cggaagacgc cggcattcat agaaagagca cccatctttt
     4681 catccacatg agcaatctta agattttcac cctcatgatc gttcaagaga attttacctg
     4741 cgatgtcaag gtagtctttg gctggaccag caaagccaaa ctggctgagg aagagggcaa
     4801 ggtaagttgc gccattgaca cctgaagcag gcatagcacc gtgggctgat ttaccaatga
     4861 tcgtcacctt gtatttgcca gcttcttctt ggagttctcc tctaagtttg tgttctgcaa
     4921 caaaggcatc tagtttagct tgcaagtcag ccaaatcacc tgaaacgact gctgttgctg
     4981 attctggtac catattttca cgtaaaccac ctgtaaagct gtgaagacgg gcagcacctg
     5041 tattttctcc tgcaaagtgg aggtattccg tgatatttcc tttttcacca ttgatgattg
     5101 gaaattcagc atctggagag aaaccgaaat ctggtttggc aagtcctacg tgctcaaagt
     5161 agtagtccat gtctgcccag cctgattctt cgtctgttcc aacgatgaag cgaactttct
     5221 tagaagttgg aagacccaat tctttgatga ttttcaaacc atagtaacaa gctgttgtag
     5281 gacccttatc gtccgaagcc ccgcgcgcat aaaggcgacc atctttgata gttggtgtgt
     5341 aaggatctgt gtcccaaccg ctaccagcag gcaccacatc catatgggca aagattccga
     5401 gaacttcttc tccatcacca aactcaaaat gtcctgcgta gttatcgaca ttcttagttg
     5461 ggtagccatc gcggtctgcg atttcaagga atttctccaa ggcttttact ggaccaggtc
     5521 caaatggatg ctgggcatca gccttgctat catcacgttc tgagttgatt tccaaaaggc
     5581 taaacaagtc agccaagagg tcttctttgc gtttttctac ttctgctgta aaatcaattg
     5641 ctgtcatttt ttcttctttc tatcttttct cgatgatttc atctactggc aagcggtagc
     5701 ttggttccaa tttgtcgtct gtgtaaccca ctgtgatcaa gagttctggg cggaaacggt
     5761 cttcgatttc caaaacttca ttaacttttg atttgtcaaa accaaggata atattggaac
     5821 caattccttg gtctgtaaga gcgagaacca agttcatagc aaccaaacct gcattgagtg
     5881 ctaggtagtc gctgacttgt tgttcattgt agcgtgcaaa ttcagctggc aaatttttca
     5941 tgaagtattg aagttgctct tcagaaaagt tattagcacc accaacacgg gcaatcttac
     6001 gagcacgttt ggctaagtcc gtatctgtaa acaaggcaat ggttacaggc gctgatgata
     6061 cctgttcaaa attggaacca taagctaact ttgccagttc agcatttttc tcacgtacca
     6121 ccacaaattt ccaaggctgg ctgttgtggg cgcttggcgc caaggttgca atttcgatag
     6181 ccgtacgcac atcttttgga tcaacaggct tatcagtaaa atgcttagtc gcatgacgtt
     6241 ttttatttaa ttcaagaaat ttcataatcg atttcctttt ctaattctac tgcttccatt
     6301 ctaccataat ttgaaagagc ttgcagggat ttttcatgat taagtttttc tatcacagac
     6361 ataaaagata tatattggtt tatcaggaac atttctgata aactagcaag tactttacat
     6421 ttgaatggag acagtatgaa aaaatttagc ctattactag ctatcctacc atttttggtt
     6481 gcctgtggga atcaagctac acccaaagag actagcgctc aaaagacaat cgtccttgct
     6541 acagctggcg acgtgccacc gtttgactac gaagacaagg gcaatctgac aggcttcgat
     6601 atcgaagttt taaaggcagt agatgaaaaa ctcagcgact acgagattca attccaaaga
     6661 accgcctggg agagcatctt cccaggactt gattctggtc actatcaggc tgcggccaat
     6721 aacttgagtt acacaaaaga gcgtgctgaa aaataccttt actcgcttcc aatttccaac
     6781 aatcccctcg tccttgtcag caacaagaaa aatcctttga cttctcttga ccagatcgct
     6841 ggtaaaacaa cacaagagga taccggaact tctaacgctc aattcatcaa taactggaat
     6901 cagaaacaca ctgataatcc cgctacaatt aatttttctg gtgaggatat tggtaaacga
     6961 atcctagacc ttgctaacgg agagtttgat ttcctagttt ttgacaaggt atccgttcaa
     7021 aagattatca aggaccgtgg tttagacctc tcagtcgttg atttaccttc tgcagatagc
     7081 cccagcaatt atatcatttt ctcaagcgac caaaaagagt ttaaagagca atttgataaa
     7141 gcgctcaaag aactctatca agacggaacc cttgaaaaac tcagcaatac ctatctaggt
     7201 ggttcttacc tcccagatca atctcagtta caataacact cttcgaaaat ctcttcaaac
     7261 cacgtcagct ttatctgcaa cctcaaagct gtgctttgag caacctacgg ctagcttcct
     7321 agtttgctct ttgattttca ttgagtataa gatatactaa aagcgattgg accagccaat
     7381 cgctttttta gtttgcattg gctattttag gaaactctta caaaaaatca aaaaaattct
     7441 tcacatcctc tacataccca tgcttttcta ttaagctggc taataattcc agattgtgcc
     7501 cctgatagtt atcgtcacga cgcagttctt catacatttc gataaaggga agccccttgg
     7561 acttggccaa ttctaactca gcttcgtaat cataagcaac tttacgaaat tggatattga
     7621 gtaattcccc atcttcaact tctatcacgg catactgggc acggtgattt tttaacgcct
     7681 cccaattaaa atagggcatg ccaatcgacc ctggattgat gatttgttgc ccttgacttc
     7741 cataacgaag caactgcttg tgaacatgac cataaactgc cacgtccgtt tccgcatcta
     7801 gcaagtcacc accatagttt ttgtcaggta aattatgaga gatagaaaag cgcaatccgt
     7861 caatttcttt cttttccagc aaaggcaagc ttcgtagcca gacaatcgtt gcaggatcca
     7921 ttcgctccat caaatactgt gtcatacgca agagctgaac ttcctgtggg tcttctaagc
     7981 catattgccc atctaaagcc tcaaggacac gatcatccca attgcctcga acacttgctg
     8041 tgataggaag gtcctttagc agggcgacta agtcatttgc gcctggacca ggaagaaaaa
     8101 tatctcccag aagccaatat tcactggccc cttgattttt agcatctgca atcactgctt
     8161 ctagcgccgt cgcattgcca tgaacatctg ataaaattgc gattttatgg ttcattgtgg
     8221 tttccttccg tttggtaatc tactctttct tctgctactt gaggcaaggc ttctccctgc
     8281 gggttcaact ttctttgcac agcctctgca acgactctag gtaccccaac ttcgacaatc
     8341 tcatccacac tggcttcctt gattttggtc aaagacttga aatgcctcat gagattttgc
     8401 ttgcgtttag gtcccagacc atcaatccca tccaattgag atgagaaaga atttttggag
     8461 cgcagttggc ggtggaaagt gatagcaaag cggtgcacct catcttggat gcgttggagg
     8521 aggaaaaatt cctgagaatt gcgagacaag tccaccacct caagcggatc tccaaagagc
     8581 aattcatggg tttggtgctt atcattcttt tgcagcccag caattggaat atccaagccc
     8641 agttcctctt ggataacctg cttagcgata ttgacttgac cttgcccccc atcaatcaca
     8701 atcaaatctg gaggagtcaa agcctcacgc tgtactcgac catagcgtct gcgaatgacc
     8761 tctctcatgc tggcatagtc gtctggtcca acaaccgttt ttatcttgta cttacggtaa
     8821 tccttcttac tcggtttacc gttgacaaag accaccatag ccgaaacagg gctagttccc
     8881 atgatattag agttatcgaa ggactcgata cgtactgggg tcgggatttg gagcaaacgc
     8941 cctagatttt caatagctcc ttgagtcttt tcgacagatt tttctagcag attgaacttc
     9001 tgctctagac taacacgagc attttttatg gctagattga ccagttgttt tttctctcca
     9061 cgttgaggct taagaatctt ggaatccacc aaggccttga cagcctcttc gtcaatatcc
     9121 tgcggaatca gtacctcatt gggaactaga tgagattttt cttgatagaa ttgtcctaca
     9181 taggtcaaaa aatcctcatc tggatcattg aagtagggga agagattgac atcgcgctcg
     9241 ataagcttac cctgacggac aaagaaaacc tgcacacaca tccagccctt atccacatag
     9301 tagccaaaga catcgcgatt ttgcaaatct ttcgccatga cccgttgctt ggttcgaagc
     9361 gttccaatag cctgaatcag gtcacggtat tccgccgcac gttcaaactc catactttgt
     9421 gctgctactg ccattttact cttgagatca tcgatgattt tgtcatcctg acctttcaga
     9481 aaatcagaca cctcctgagc catagacttg aaataagcct catccttctt acagatggtg
     9541 tgggccatac actggccgat atggtaataa aaacagacct tagagggcgg gttggtacat
     9601 tttcgaaaag ggaaaatcct atctagaagt cgcttgattt cattggctgc ccccacatct
     9661 ggataagggc caaaataaag accaccgtcc tttttgacct gacgagtaat gataagccgt
     9721 ggatagcgct cattggtgat tttgatgaaa ggataggact tgtcatcctt gagcatgata
     9781 ttgtacttgg gcttgttttc cttgatcagg ttgatttcta ggagaagtgc ctcaatatta
     9841 gactccgtaa caataaattc aaaatccaca atttcagaca ccagagcctc tgtcttggta
     9901 tcatgacttc cacgaaaata ggaccgtact cgattacgca gatttttagc ctttcctaca
     9961 tagataatgg tgccattttt atccttatga atgtagcaac cagggctggt cggcaagagc
    10021 tctagttttg atttaatcaa gttgttcata gttccattat agcaaaaaaa gtagggaaag
    10081 atagtaccct actcactagt ctcatatatt tttcggaggt ttgcaacatc ctcttcctgg
    10141 ataccataaa aggaacctgc tggttgcatg acagacttct catctgtatg gtccaagcca
    10201 atcgcatgac ctaactcatg ttctgccgta tggacaaggc gttcatagga gtagccatag
    10261 tatggattgg acaaataata atgattcaac cgcaccgtta cggacaagaa ttgccctgtt
    10321 aagagattag tttgactttc cgcctctcct gccacaggag tgcctccgtc gttcatctcc
    10381 gtagccgtaa tatccgcctt actagactca gtcacgagtt caaagttaaa agcaccagtt
    10441 tgattccagt tctggattgc ttctaaataa gcctcttgaa agcgtgaatc catctgcgga
    10501 tccaggtaaa tacgagcaga ggcctgtgcc caccttcctt cagaatgctg gtgactatct
    10561 gtctggctta acttaggcag ttgccctgtt ttctcccatt ggtcaatact ttgttgacca
    10621 atttttactg accgttctgc ttgctttagc gctccttgaa aatccccgtt cagataccag
    10681 agaagtccga aagcaagcac acataagagc acaactatcc aaaccagacg ccaaaacaaa
    10741 cgccacacaa aagaaaagaa agcccctatc aaacgaaaaa gccagcgcat gtctctccac
    10801 ctttctagca aataagaatt attttactaa aagaagctaa aagaaatcta aatactgact
    10861 ttttcatctt aacgtcctac tatttttttg agtaactgga tagctttgta ttttaaaggc
    10921 gatggatggt aacggaaagt acccgctttg cgtacaatat agccattaaa attctgttta
    10981 aaacgcaaaa caccatcact tccatcaaaa atcccttgaa tgcctaggaa gttgtattta
    11041 ggtattccac gttttatgct ttccaacata acatattttt gaagcagggc aggggcatag
    11101 aacttattaa actcagtgta ggaaccacta aagagataag tcgtttcctg aggcatataa
    11161 acaaataaac tcccagctaa aacaatatct tcttctccat atttttcaat caagtctcgc
    11221 gcttctgctt ttcgaacttc aaacgtttca aattgactag aatattctct cagttgattt
    11281 tgttttttct cagaatgagg atttttactc aaatcaagtc gcaacttgtc caagttttct
    11341 tctagtttac tttgttcacc ttgcaatttg ctcatatagt ccgaaaaatt taagcttgct
    11401 atgagaaact ccgcttgttc tccaaaagta tcataaaaat gctcataata ttctaaactt
    11461 ttatcactat attctctacg ttcagaggtt tcttttgtta tattcttaaa aatcgatagt
    11521 tcttcacgtt ttaacttttt caaccgaatg ccaaaggttt cagccttttt caccaagggt
    11581 ttaccctttt tgctaaaact tttaagcaaa ctcttttcag ttaattcagt taaatcttta
    11641 tagtataacc aatctggttc tccacctggg taacctgttg ttaagccatc aaattgataa
    11701 cctaaatcag tcaaaccttg aataatactt tttttctcag catctattgg attaccttgg
    11761 ctatcaaaag tttgataagt ttcataaggt tttacaagca actctaatac accattttgc
    11821 ttggcatatt cttttaactc tgcataaaaa actggaagag catcttgttg ggtataaatc
    11881 ggccccgaat tgagttccat atgcagacca cccagcatgg gcaagctata aaccagagct
    11941 gcaacttgaa tttctccttc ttgtttcaaa gcaagataaa caattcgagc ccctcttttt
    12001 tctagcaaat cccccatctg gacagattgc ataaaggaac gagaagaaac ctgatcagaa
    12061 taagtctgaa actcttcttt cgtgagtgtt gttagtgcca tatacttact ttctatgttt
    12121 ttttcttaat gttttacgga aatcaagagc aagtcttaac agaggataga gaggatgagt
    12181 gggcattgta aattcaccca agtattcttc aatcgttgga ttaaattttt ccttaaaatg
    12241 ataaagtcca ccattgagag agttttcaac accacctaaa ttttgccaaa ccatacctcg
    12301 ctcaaaggca tagcgagccg tttcatacca tgttaaaatt ggtgcattgt aacgtttaaa
    12361 atcatcatcc ataccagcat atatattgac agaggtagta ccaaattcca aactcaaagt
    12421 agccgctaaa ggaactctcg cttgacctac atctatatat tcctgcaaga aggtcaattc
    12481 ctctaacaaa cgttcttttt ccttcttctg cgcttctact tttgaaattc gagtcgactc
    12541 agtaaaggtc tcttccaagg ctctattttt tgctaactgt tcttctaatt cttgcgaacg
    12601 tttagaaaca tccaaggtgg ccaaggtgat ataggccttg tccttaaaat tatctaacaa
    12661 ttttttataa taggcttcat tcctcaaatg aatctctttt cgcttctcag tttttttcat
    12721 caactccgaa aatgaatcta atagttccag tccaccatat tgaatctcaa gccctttgtt
    12781 tcgtgctgtt cgaatagcct gttttgttga cttggaaagt ttatcttctt caaaattttc
    12841 cttgtatatt ttcgcctgaa tacgaggttg aatggtgtct cccatttcct ccgtttttcc
    12901 tgaccacctt actcccattt gttgcaaact atcaataata gccagatttt caggaaattc
    12961 tgtcttttcc tgattgatta aactttgaga taggcaaata cttgggtcaa aagtcacaaa
    13021 aaccgctctc ttactgcgag cataggactt aatagactga atgacaaaat tcaagagttc
    13081 tttatcccca taatccaata taggtcctct tgggatgtaa aacattttat agcctagcgg
    13141 aagagttcta atcaaaatac tagctgtcgc cagtaatttt tcttccctgt aaacaccaaa
    13201 cttctcatgt tgccaattag acttaacttc ctcccaagca ctactttgta atacattggc
    13261 taattcatgt tctttgacaa actgatcata ttctaatgtg ggaatgccaa tttgataacg
    13321 gtacatttcc tactctcttt cctccagtat tttattacta ttctactact ttcgtttgaa
    13381 aagtctagtg aaaacatatt ttattttagt tctactcccc ctatgctgaa gttcaaacta
    13441 agtcagtctc tcttctaatt tgaaatcaat tggtagggtt gttaaaaaaa cttccaattg
    13501 tttttcccag tagtaccact cgtgagttcc agcgctatgg ctataggtca catcaaaacc
    13561 tagttttttg agatttttca ctgcgagatt attggcttcg tacaagaaat cctgttcgcc
    13621 acaccacgcc caaagtttgg tctttttatc cgatttttta gccagacttt caagagaata
    13681 gggactagtt gtccagtctt taatctctcc aaaaacacct ctccagtagg ctggacttcc
    13741 cagattttga ctttcaggag aaaagttttg aaaactgagg gcacctgaaa agctagctgc
    13801 atgagaaaaa cgatttgtcg caagagccag tttgaagcag ccgtagcctc ccatagaaag
    13861 accagcgata aaggtctttt cacgcttgct agtcatatta gggaagaagc gtttcagaac
    13921 ctgtggcaat tcctctgcta gagccgtgta gtagtcaaaa ccatactggg tatcggtgta
    13981 ccaaccattg ctggtattgg gcataacaac gatgagatta gttcctcgaa gcaagcgttc
    14041 tacattggtc cgcttaagcc aactattatg atttccagac atcccgtgca aaaggtacaa
    14101 gacgggaata tcttcacact ctggttcttc cactcgattg gcatcagggt agaggacatt
    14161 caccccccac tccatatcca atacttgtga gtaatactcg attttcatta ctgccatgat
    14221 tttctccttc tatttttcta taagaaaaag ccgaaactcg actttctctc tgtttatttc
    14281 aacgattatt ttgcttccat gactactggt aaaatagctg gacgacgctt ggtttggtca
    14341 aagagatact tggtcaaatt atctcgaacc ttccctttaa gatctgccca gtcaaagtca
    14401 tctccttgaa gatactcttc taccgtttgg ttaatcaatt ctgaactttc atggagaata
    14461 tcgcgactct tcttgagata aacaaatccg cgcgtatgaa cacgagccct agccacaatt
    14521 ttcttctcac gacggttgac tgtaatagcc acgatgaaaa ttccatcctc tgacaagacc
    14581 ttacggtcac gaagaacaac atttccaaca tcaccaatgg cattcccatc aatcaagata
    14641 tctcctgctg aaaccgatcc agctggaaca aagtctccat tctcgtaagc catggtcgtc
    14701 ccctttttag gaatgaagat gtgttctggc aacatcccaa ctgccatggc agccttagcg
    14761 tgagcatcca actcacgata ctccccttgg acagggaaga ggtacttagg ttgcaaaaga
    14821 ttgatcatca gctgcaaatc acgcacattt ccgtgccctg atacatgtaa actttgggta
    14881 atcaatttga caaccccacc tgcctgataa atcatatttt ccacacgcgc aacaaaggct
    14941 tctttagcaa tagacggagc cgtagcaata tagaccaggt ccccatcctt gatttctaca
    15001 taacgatggc gaccaatcga catcttacga agtccattga taggttcacc catacgacct
    15061 gtctcaagaa taatcaactc atggtcttca aagcgagaca tatctttagg cttaatcaag
    15121 agaatttcgt tggctaaaga caacttctta agacgaatcg ctgtgcggac gatattttca
    15181 atatcaaatc ctgtcaagac gatacgtcga cctgttttat ccgcagcgtc aaaaatctgc
    15241 tgaatacgag aaagattact ggaaacagct gcaacgatga tacgaccttc ccagtcagca
    15301 atagtttggg taatttcatc cctaacttca ctttcactag ccacctgaat attgctgtct
    15361 gcattggccg aatcactgag gagagccagg acgccgtcac gaccaatctc tgccaaacga
    15421 gcaaaatcag ttgcataaga ttcactagcc gtttggtcaa atttgaaatc acctgtataa
    15481 acgatgcttc cttccgatgt cttcaagaca attcccagac tctctggaac ggagtaagtc
    15541 gtagggaaga aggaaaccac tgtcccacca aaatcaatct ccgtattctc atcaatgaca
    15601 tggaaatcat taaatttctt aacggcatca tttcctttga caaagagctt tgccaactca
    15661 atggtcaact cagacccaaa tacaggaact ttagcctctg ccaagagata aggtagagca
    15721 ccaatggcat ccgcatgccc gtgggtcaag aaaaccccag caatacggtc gctattttca
    15781 aaaaggtaat ccatgtttgg aatcaccaca tcgaccccta attgttcatt ttcaggatat
    15841 tttaacccta cattcaaaac aaaaatggac tctccaattt cagcaatgta catatttttt
    15901 ccattctcac gcacaccacc aagtgttgtt aaactgatat tactcatttt tcctccaaaa
    15961 tcttagttta tcttgattat agggcaactc taccctctta ttctaaaagt tctaatactt
    16021 tcagccgaat cttttcctac cattatacca tttttttgat gattttcaaa atgaaggtct
    16081 gttttcaaaa aagagttgat ttcccaactc tttcctaact tctactcttt ttccatcaaa
    16141 aaatcataaa tttcttgcac cgtacccagc gccatcattt cttggtcttt aacggtttgt
    16201 ttgagatttt ggtaaatttg actttctcct atctcccgct ttggcgcctc tttattgact
    16261 gtcatcacac catcttttat cgtcacaaag cctagttctt caaatacttg aatcatcttg
    16321 accagcaaga tttgttgaat attaagatat gcagccaaat ctttcagctt gtagcgaata
    16381 tcaaactctg ggaactggta aatagtcttg tacaatttgg caaactgatc tctagtccca
    16441 taacctgtca gataataggc cttgtcaata tcatttttga aatagacagc agagaaatgc
    16501 tgttcctgaa aaatggtctt cagctgagta atatcctctg gaatgttttt tacgacaata
    16561 gcttcactag ccgcaagatt tggcagttct ccaggaaaat ccaagactgg aacaccttct
    16621 ggcaagactg cattttttcc acgaatgtta aaaagttgaa caccttccac tcgcgcatcc
    16681 accatcatca actggagggc agtttggcca ttccattggt tgacagacaa tttaaccgct
    16741 aactctagat tcttggtttg agaaaactct gtcgcccatc tgccttgacc aaaggctacc
    16801 acttcaaaac tcgcctcacc cttggaaatt ttcagcttta gatgggcatt acctgccccc
    16861 atagtacgag cactttcgac ctgaaaattc ttgatataaa aaataggttt ctgattatcc
    16921 attccaaaag gagctaaacg ttcaaaactt ttgaccgttt ccaagctaag tgcctccaaa
    16981 tccaactctt catctaggtt taacttattc ttgccaccag catctgcacc tttttcacga
    17041 acataatctt ccaaaacctg agataaatct gagagttgct caacttccag cgtcataccc
    17101 gctgcacctg catgacctcc aaaggcgatg aagaggtctc gatggggatc cagagcttca
    17161 aaaatatcga ccgcttccac actacgagca ctgcccttgg cacgaccgtc ttctatatta
    17221 agaacaatga ctgtctgtcc caattcttcc aataaacgac cagccacgat tcctagaacc
    17281 ccaggattcc agccttcctt ggccaagacc tgaaccttct tctcaggatc caccatggtc
    17341 ttggcttctt catagataga ctgaacgatt tccttgcgct cttcgttttt ctggtgaatc
    17401 ataagggcaa tctcatgcgc ttcctcatca tcaaatccag tcaacaaatc aatggcagga
    17461 ttgggatcat ccaagcgacc caaggcattc aaacgaggag caatctggaa accaaccgtt
    17521 tcttctgtta cttcgttggc agcaatccca gccatgtcca gcatttcttg cagaccaatg
    17581 cgctgggtat gacccaacat ttccagacca tattgaacta agatacgatt ttcatccgtc
    17641 agactcacca tatctgcaat agttccaata gcgaccaaat caagcaattc cacttgcact
    17701 tcttctaaca gggcacaagc caacttgaaa gcaactccac aaccagccaa atatttaaaa
    17761 ggataatccg catctggatg ttcaggatgg acaatagcat aagcatctgg cagggtttca
    17821 ggcatggaat gatggtctgt cacaatgaca tctactccca tagactgagc caatgcaata
    17881 gcctcatgac cagcaacccc attgtccacc gtcacaatca aggaaattcc ttcttgctcg
    17941 ataaagtatt tataaacact agcattaggg ccatagccat cggtaaaacg atttggcagg
    18001 taaactcggc actccgcacc aagttgttcc aaactttcct tcacaataga agccgaagtc
    18061 atgccatccg catcatagtc tccataaacg agaatatttt ccccttcttc aatagcctga
    18121 cgaatccgct ccactgcctt gtccatatca tggagcagat aagcatcatg taagtcctcc
    18181 aaggaaggtt ctaaaaactt cttcagactt tcttggtcct gaatccctct ctcaaacaat
    18241 aaccgagcca cctcaggacc cagtccagcc ttcttggcta tctttgtaaa atccgcatct
    18301 tctacctgca gggcaaactg ccattcataa gtaggtgtta tcaaaaagac atccactctt
    18361 tctaagaatt ctattgcttc attataacat gatttagacg ttttctctat ccagattgct
    18421 tttttataac attttatagt atattgaaac tagaatagta cacctctact tataaaatat
    18481 tgttagaaat cgatttgact gtcccgatcg atttgtcctt ttcttatttc actatagtga
    18541 attttttcag atacggtttg acaagaacat tcttttattg tagaattgtg ttataaaatc
    18601 taacataaag gagatctctc atggctttag tagaatttaa aaacgtcgaa aaatattacg
    18661 gagactacca cgcactccgc aacatcaatc tccgttttga aaaaggacaa gttgttgtcc
    18721 tgcttggacc ttctggctct gggaagtcca ctcttatccg tacgatcaat ggtttagagg
    18781 ctgttgacaa aggaagtctc ctagtcaatg ggcaccaagt tgctggtgcc agccagaaag
    18841 atttggtacc tcttcgcaag gaagtcggca tggtttttca acattttaac ctttatccac
    18901 acaaaacggt gttagaaaac gtgacacttg cgcccattaa agttctagga attgataaaa
    18961 aagaagctga aaaaaccgcc caaaaatatc tggaatttgt aaatatgtgg gacaagaaag
    19021 attcctatcc cgccatacta tctggtggac aaaaacagcg gatcgccatc gctcgtggtc
    19081 ttgctatgca tccggaactc ctcctctttg atgaaccaac atctgctctt gatcctgaga
    19141 ctatcggaga tgttctagca gttatgcaga aactggcgca tgatgggatg aacatgatca
    19201 tcgttaccca cgaaatgggc tttgctcgag aggttgcgga ccgcattatc tttatggccg
    19261 acggagaagt tttattagat acgacagatg tcgataactt ttttgacaat ccaagcaaac
    19321 ctcgtgccca acaattcctc agcaaaatta tcaaccacga aagtgacaaa gtcaaataag
    19381 gaggcgccta tgaaaaaaaa attcttttta tcagcattat tgattagcct tttcggcctt
    19441 gctgctgcca aaccagtcca ggctgatact agtatcgcag acattcaaaa aagaggcgaa
    19501 ctggttgtcg gtgtcaaaca agacgttccc aattttggtt acaaagatcc caagaccggt
    19561 acttattctg gtatcgaaac cgacttggcc aagatggtag ctgatgaact caaggtcaag
    19621 attcgctatg tgccggttac agcacaaacc cgcggccccc ttctagacaa tgaacaggtc
    19681 gatatggata tcgcgacctt taccatcacg gacgaacgca aaaaactcta caactttacc
    19741 agtccctact acacagacgc ttctggattt ttggtcaata aatctgccaa aatcaaaaag
    19801 attgaggacc taaacggcaa aaccatcgga gtcgcccaag gttctatcac ccaacgcctg
    19861 attactgaac tgggtaaaaa gaaaggtctg aagtttaaat tcgtcgaact tggttcctac
    19921 ccagaattga ttacttccct gcacgctcat cgtatcgatg ccttttccgt tgaccactct
    19981 attctatctg gctacactag taaacggaca gcactactag atgatagttt caagccatct
    20041 gactacagta ttgttaccaa gaaatcaaat acagagctca acgactatct tgataacttg
    20101 gttactaaat ggagcaagga tggtagtttg cagaaacttt atgaccgtta caagctcaaa
    20161 ccatctagtc ataccgcaga ttaaggagga taccctatga cagatttatc atcttggaca
    20221 gcctattttc aggattttgg acaatttttc aatggtttcc tctttactct tgccctagcg
    20281 attggatcct ttatcctcgc catggtctta ggaatcttct ttggtgccat gtcaaccagt
    20341 aaacgtccaa ttttacgcat tttagctcgc atcttcgtgg aattttacca aaacactccc
    20401 ctcttggtgc agtttgttat tgttttttat ggcctacctc ttatcagtga ccacatcatc
    20461 atgattccaa tttattggac agccgttctc tgcgtgggac tctatcacgg cgcttatatc
    20521 gctgaggtta ttcgttcagg gattcagtct attcctagtg gtcagatgga ggccgccttg
    20581 tcgcaaggtt ttacctatat cagtgccatg cgcttgatta tcttgcctca ggccttccgc
    20641 atcattctcc ctccattgac caaccaaatt gttaacctca tcaagaacac atctactgta
    20701 gctatcatct ctggagtaga cttgatgttt gtgactaagt cttggtcggc tctcaacgga
    20761 aactatatcc cagccttttt aggtgctgct cttctctact ttgccctatg cttccctgtt
    20821 gcccagtttg gtcgcaagat ggagcaagcc aataaaaaag cctattcact ttaggaggtt
    20881 actatggaat ctattttaga aattttaacc ccagataacc tagtctttat ctttaaagga
    20941 tttggcttga ccctctatat ttctctgatt gccatcatcc tctctactat catcggtacc
    21001 gtgcttgccg tcatgcgaaa tggaaaaaat cctatcttac gcattatttc cagtatttat
    21061 atcgagtttg tgcgcaacgt tcccaacctt ctctggattt ttactatctt tttggtgttc
    21121 aaaatgaaat ccacaccagc aggtattaca gcctttactc tctttacatc agcagccttg
    21181 gctgagatta ttcgaggcgg tctcaatgcc gtagacaagg gacaatacga agcaggaatg
    21241 tcacaaggct tcacctcagc ccaaatcctc tactacatca ttctcccaca agccatccgc
    21301 aaaatgctac cagccatcat ttctcagttt gttaccgtga ttaaggatac cagtctcctc
    21361 tactctgtta tcgccctaca agaactcttt ggagccagcc aaattctcat gggccgttat
    21421 ttcgaaccag agcaggtctt cagtctttac atcctgattg ccctcatcta cttcagcttt
    21481 aacctagcga tttctagcct gtctcatatg ctagccaaac gttggcaaca agctgcagaa
    21541 taatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ctcaagtaca
    21601 gcctgcggct agcttcctag tttgctcttt gattttcatt gagtataaac agccactctc
    21661 cagttcaatt ggagagtttt ttgatgagag tagatattta tagacctcaa tttgacacca
    21721 tacattttct atgataaaat gtaacaaatt catttacaac aaatcgaaat ctaaatgaaa
    21781 tggaattttc tatgaaatca gtcaaaggac tactctttat catagctagt tttatcttga
    21841 ctcttttgac ttggatgaac acttctcccc aattcatgat tccaggacta gctttaacaa
    21901 gcctatctct gacttttatc ctagccactc gtctcccact actagaaagc tggtttcacg
    21961 gtttggagaa ggtctacacc gtccacaaat tcacagcctt tctctccatc atcctactaa
    22021 tctttcataa ctttagtatg ggcggtttgt ggggctctcg cttagctgct cagtttggca
    22081 atcttgccat ctatatcttt gccagcatca tccttgtcgc ctatttaggc aaatacatcc
    22141 aatacgaagc ttggcgatgg attcaccgcc tggtttacct agcctatatt ttaggactct
    22201 ttcacatcta catgataatg ggcaatcgtc tccttacatt taatcttcta agttttcttg
    22261 ttggtagcta tgccctttta ggcttactag ctggttttta tatcattttt ctatatcaaa
    22321 agatttcctt cccctatcta ggaaaaatta cccatctcaa acgcttaaat cacgatacta
    22381 gagaaattca aatccatctt agcagacctt tcaactatca atcaggacaa tttgcctttc
    22441 taaagatttt ccaagaaggc tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc
    22501 atggtcaaac tctttacttt actgttaaaa attcaggcga ccataccaat aatatctatg
    22561 ataatcttca agccggcagc aaagtaaccc tagacagagc ttacggacac atgatcatag
    22621 aagaaggacg agaaaatcag gtttggattg ctggaggtat tgggatcacc cccttcatct
    22681 cttacatccg tgaacatcct attttagata aacaggttca cttctactat aacttccgtg
    22741 gagatgaaaa tgcagtctac ctagatttac tccgtaacta tgctcagaaa aatcctaatt
    22801 ttgaactcca tctaatcgac agtacgaaag acggctatct taattttgaa caaaaaaagt
    22861 gcccgaacat gcaaccgtct atatgtgtgg tcctatttct atgatgaagg cacttgccaa
    22921 acagattaag aaacaaaatc caaaaacaga gcttatttac gaaggattca agttcaaata
    22981 agtaatcata ctctcctggg atttcccagg agagtttttt atagccaaat gaaataagac
    23041 ctgaacgatg gaattttggc attcaaatca attgataaga atattttata gtggagtgaa
    23101 ataggatacg aacaaattga ttaggaaaat caaatgaatt tatagaaatc ttttagcagt
    23161 tatgttgtcc tattctagtt tcgaaacgct atagaagcag cattgtgcta gtctagattc
    23221 agtttactat actaaaacga gtagcttgga atcaaaaaac ccaccctcac aggcaggttt
    23281 tatctgtatt attcagctag attatgcttt accttctgaa ccgaatacgt cgatacgttc
    23341 ttcaaccgat gcttggatag cttttacacc gtcagccaag aatttacgtg ggtcgaagag
    23401 ttttttcttg tcgtattctg cttcgtttgc ttcgtagtca cgagcaaatt tacgagttgc
    23461 gttagcgaat gcgatttggc attctgtgtt aacgttaact ttggcaacac caagtttgat
    23521 agctgcttgg atttgctcat caggaatacc tgatccaccg tgcaatacga ttgggaatcc
    23581 tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca agaccttccc agtttactgg
    23641 gtaagggccg tggatgttac cgataccagc tgccaagaag tcgataccag tttcaaccat
    23701 tgctttagcg tcttcgattg gagccaattc acctttaccg atgattccgt cttcttcacc
    23761 accgatagta ccaacttcag cttctactga gataccttta gcgtgtgctt tttcaacaac
    23821 ttctttagcc aatttaaggt tttcttcaac tggaaggtgt gaaccgtcaa acatgattga
    23881 agtataacca acttcgatac actcaagtgc atcttcgtag tgaccgtggt caaggtggat
    23941 agctactggt acagtgatac ccattgattc aacaaggtta gcgatcaagt tgcgagcaac
    24001 tttgtaacca cccatatatt tagcagcacc cattgaagtt tggatcaaaa ctggagcttt
    24061 tttagcttct gctgcgcgca agatagcttg agtccactca aggttgtttg tgttaaatcc
    24121 accaactgca taaccgttgt cacgggctgc ttggacaaat ttttctgctg aaacgattgc
    24181 cattttatca ggcctcctgt atatttttat gggtcatccc atttacattg ttcattttat
    24241 cactttttgc caaaaaaatc tagtttttcc cgcagtttcg attgattttc ttctaactcc
    24301 atctatgtaa accctttctc tccctagtct tggacgactt ttggaaaatc tataaagaag
    24361 gttaaacgat tctcctccat ctcgaaacga taagctaatt tttcatgttc taatagactc
    24421 ttaaccacaa agagccccat accagacccc ttgaccttgc gactggcatt gtcagaaaaa
    24481 gactgggcta gtttttcttg ttcctctgag ctacagctat tttcgataaa aagttctcct
    24541 tctctttctc caattcgaac taagccacct ggaacagagt gcttaatggc attgctgatg
    24601 agattagaaa gaatcaactt cataactgat gggtttagat aagcctgctg atgggtcaaa
    24661 ctattgtcta tctggagctc tctttccttg gctagcaagg cataatcttt gaccagattt
    24721 tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc gcaattcctg cacagaagag
    24781 agggaaagta tctgcagaac atggtgattg agttcatcca caatccccaa ggcaactccc
    24841 agatactggt ctctattctt ataacgaccg atattctctc tcatattttc gattaggatt
    24901 ttcaaactag ccagcggtgt tttcaattca tgagaagctc ctcgtaggaa ttcgaccttc
    24961 atcttctcca gctggagaat ggcttcattc ttttcatgca agtccgcaat aacagtcaag
    25021 agatgctggt agaggctatt gatttgttcc ttgagattgc ctatctcatc cttagaatcc
    25081 acgcgcaatc gcacttggga atccaggtcc atcatccgac gggtcacccg cttgatttcc
    25141 aaaatcggtg caacaatagt ccgagcgtag atgtaggcca ccaagaggga aatcagaaag
    25201 gaggccagca aggtataggg aagaaactgg agactgattt gctccgcttc cttttgtaaa
    25261 tccatggaag ctagaaactg gagaatcata gtaccaccgt cttgcgtttt cacctcgcgc
    25321 tcctcaataa agagagaggt tgtctggcgg tctgtgtcca gaggaagact gtccttgact
    25381 tctaacttgt cctcggtcat ctcacctttg acggtcccct tgatatcact agtctgggaa
    25441 tacaagtcta acacttgctc gatactctgc ctatctttcc cttctaggga ctgggcaatg
    25501 gctgttgcct tttgaccaat ggtttcctga cgatgactca gataagtcga aggaaaaaga
    25561 aaataaatag ctaaatgaag gcagataacc agaacactaa atatcgagaa ggtatagata
    25621 aatatctttg taaataaacc tgttcgtttc attttcgctc caatttataa ccaacattgc
    25681 gcacagtgag gatacaatcc aagtctagct ttttccgcaa ttccttgata taaacatcaa
    25741 taacacggtc aaagggaacc tcatctgtcg ctttccagac ggcatcgata atctgagacc
    25801 gagtcaaggc ccggccttca tttttcacta gatagtccag aatttccaac tctttggcat
    25861 tgataggcac ttcttgacct gcgaggcttg cactgtagct ttcaaagtcc accttggtat
    25921 ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt gaaaatcgcg tccaccctca
    25981 cttttaagag ggagagggag aaaggttttt ccagatagcc atctgccaaa gaggcaaagg
    26041 cactcatctt gtattcctca tcctgaaaag ctgtcaacat caagacagga acctgactgg
    26101 ttttacgaat ctcagctagg acttctaagc cgttaagctt gggcatctgg atatccagta
    26161 aaaccagggc cacctcatag ctagaaaatt gctccagagc ttcctgaccg tccgctgcct
    26221 caatagtttc atagccacaa tccgtcaaat aatcactgac cccctcacgg atcatctctt
    26281 catcttctac aattaaaatt ttcatacttt aactgctctc tattttttat ttttcttaga
    26341 ataaatacct actctatttt ctattatagt ctcttgctgg ccttttgtct gtaagcaact
    26401 gaccactaga taaaacgttg tgaaattcct ttctcataaa ttccataact ttagtatatt
    26461 atatttaagc actaaagtac aaagaaagca actgaaagca atgattttca ccactgcttt
    26521 cagatttatt ttgaattgtt aaatagctat tcctatccac tattcttgaa tagaaacaca
    26581 agatgcaatc tttattccag actcattttt ttcaaattta ttcaccatcc agcaagagct
    26641 cttttggttg ttttctaagg agattgcttg aagcaagcgc cataacgaga accactagaa
    26701 ccaaggcaag gacaaaaatg atgataaagt ctgatgtctg aatggaaatg tctaggctcg
    26761 acaaggtctt gctaaagcca tctacttctg caccgccacc aaggttagag gcttgagccg
    26821 ccttactagc ctgtttggca acacctgaag tcacattggc aaggacagtg tttccaattg
    26881 cacgggcagt gtaattagct aggaagtaag cagaaactag agcagggata gcaatcaaga
    26941 tagattcggt gatgaattga cccaagatac ttgcctgctt gagaccaata gagaggagga
    27001 ttcccacttc cttgcgacgg gcattgatcc aaagactgag caagagggca aggagaagga
    27061 ctgagaagct caagctaccc cagaagagga ggttggccat cttgtacata ccagagatag
    27121 attgctcaag agctgggtag ttagaggagc tcttgacgag tgtgtagctc ttccagttga
    27181 taccactgat gccattcaac tctttcataa catcatccaa gttcttgtct gctgttacaa
    27241 agaaggttgc gtccccataa atggctgtgt cttctgtgta tccataaagt tttgcagcag
    27301 tgtgaatgtc tgtaatagct gtgttttcgt aaagttcttg tgagtaggtt actgctgact
    27361 tattatgacc atcaaagagt cccttgattg tcacttcaac tgtttccttg gctccttttt
    27421 cattatctgc atcgtagata ttagagtcca gtttaacctt gtcccctact ttccagccgt
    27481 gtttggctgc caagtccttg tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct
    27541 ctccttcgac tagtttataa gaaccagaga caaacttatc ttctttagag gagtcattga
    27601 cacctgtaat catcaagcta cttccaaaac gtttggcacg atcagcagtg agattcttct
    27661 tggtttctgg cgtttcaatc aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt
    27721 tgacataaga ctcaatggcc ttgttttcgg tgattttttt gatgtcttca cccttgatat
    27781 tcccagcacc acgaggcgtt ccttggttga cgcgacgatt gatttgcatg gagaagctat
    27841 tggtgatatt tttaaaggtc tcctgagaag ccttggcagt agctcccttg attgacaagc
    27901 cgaccaaact caagctcgcc ataaggagaa taatcaggaa gatgacaatc gatttgaaaa
    27961 acttccttgt aacataggca aatgcgttgt gtaacataga ttccctttct agattttgtt
    28021 ttaatcattc tatcaaaata agctcaaatt atttactagt attgcgcgtt tcagtcagtt
    28081 tcttatcctt taattcaagt gtaatatctg acgcttgtgc cacttcttta ctgtgagtta
    28141 cgacaatcac acatttacct gttttctggg caagtgattt gagtagttcg acaatatctc
    28201 cagcagtttt aggatccaga tttcctgttg gctcatcagc tagaataact ggagcttctg
    28261 agaccaaact gcgagcaatg gcaacacgtt gctgttgacc acctgataac tggagaacat
    28321 tccgcttaat ctggctttca tccaaaccaa gctcaagaag tgtattcttg cttgcctttt
    28381 tgttgaccaa ttggatattt tccagcggag aaagataatc tatcaagtta taattttgaa
    28441 agaccaggga aatatggtgc atgcgatggt aagaatagcc cttcttacga atatcctctc
    28501 cttgaaaaag gatagaacct tcaacaggac tatctagacc agcaagtagg gacaagagtg
    28561 tggattttcc tgctcctgac tccccaataa tactgtaaaa ttttccgggt tcaaaattat
    28621 aattgatctg atataggact gcttcagcag tattcttata acggtaggta acatcttgta
    28681 attgtaataa agtcatgatt tctccttctt aactaataga tgataaaatt tctttcggtg
    28741 attttctaaa taagaatagg aaacaaaggg ctacagataa gcaactaagc agaactagaa
    28801 aaacatagga ttctgcaaaa gataagatgc tagttgataa actgcttgct ttggctagtg
    28861 tatcttgtaa gcttacctga tctccacttg ctagtagagt ttggagtagg taagttgtga
    28921 ttccgtttcc tgcaacaaat gctggaagca aagctccaag agataccaaa actacctcta
    28981 aacagaattg taggaagatc gagctcttgc cttttccaag tgcaagtaaa atccccactt
    29041 catagacccg ttctctcaac cagagagaca aaaccagaat taaggctcca gctcctgcta
    29101 tcaacatccc ataaaggaag atggtcagga aggtttggaa agttgcaact gagtctttga
    29161 tttgttcaaa agccttgttt tccttttcga cttggtagcc ttgattttcc aaggccaagt
    29221 tttctacctg cttcatgagt ccgtccattt ccttaggatt ttctacatag aagcgtgctg
    29281 cactgacttg agcttcacta ttgcccaaaa gggtttggct actttcataa tctgtaaaga
    29341 cttgattttc actgaagtca gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa
    29401 agatgccgat aatctcaaac tctactgttt gtccttttcc agattcagac tgaccagcat
    29461 ccaagccaat cttgtcatga agtgaaagac cgttcttctt agccaattct tcgtggataa
    29521 ggattttctt ggaatcccct ttttgaaggt gtcgcccttc ttttagattg aaagccgaac
    29581 tggtaaaggt tacatccttg gatgaatcct caagagccgt taagctaacc aagttattgt
    29641 ctgcagctga taaatcatca cgctccacgc tctgctcgcc agtcactgct tccttgtctt
    29701 ttagttttgc gaccgtctca agttcaggag agacattttc cagcccctta atcttgctta
    29761 cagatgctag gtctgacaac ttgaatgtct gaccattctc tatcttctta atagaaaaag
    29821 atgtattgag tgatttataa agattgcttt ctactgtttt gttggacttc atcagagtca
    29881 aacaggctga aattccggcc aataagacca ataaaatcag aaataaaata aaacttctca
    29941 gtcgctttct gctgacataa gcccaagatc tttggattgg attcatttgt cacctccata
    30001 tttgtaagac tattataaaa cccaaatatg aaatgtttat gaaatacgaa aaaaaatatc
    30061 gagtagggga taatctctag cccctctcac accaccgtac gtgccgttcg gcatacggcg
    30121 gttcaactaa cttttaacgc atgtcgttca aggtaataat ccaaacacga aaccagtcca
    30181 cgtttttcaa ggactggttt tgatatagca cgtttaagta ccgacttctg agctactata
    30241 gtagattgaa actagaataa tatacctcta cttctaaaat attgttagaa atcgatttga
    30301 cttccctgat cgattcgtcc tattcttatt tcattttaat ataattgata gtgctcgccc
    30361 cagccagata ccttatctgc tatccattta ggaaccccta acttaagcaa tccccataat
    30421 cgtctcgatt tcttcttcca ttgcttccag ataatcactc gtaggcgagt acgcaagcgc
    30481 tcatctatgt tagtgactat acttttcata tttataattc attcctttcg tttcactcaa
    30541 ggcacaacac agaatgaaaa agtgttgtga tctttatttt gttttataat aatagtgaga
    30601 aagcctatca ctactacaaa tcacggggag gtgaataagt gagtggtaca gccactacct
    30661 cgcatatttt gtcacatcat ttaacggtac ataataagtt gtaccatctg aataagttgc
    30721 tacaatatca tttgcatgct ctccttcacc tttagcaaag gttggagctc ctgctggatg
    30781 atttttattt gcctctttca atttttcaat aatggcattt ttttctgtat cttttatatt
    30841 atcaggattt ttcactaaaa ttttgtctgg atatgtcggt ttagcagaaa caatttttac
    30901 tgttacttct tttttattcg aagcacttgt ccagtttcca gcattatctt tagcatttaa
    30961 ttttacagta attcctgaac taggaacttc agtagcaggt tgattatcaa cattattcaa
    31021 ctttaatttc aaaagagctg ttgcatcaga cgttttatca atcgttatat ataatgatga
    31081 attgttatta taaccagttc cttcatattt agctgtttgt gagctacttg aaacagaact
    31141 gaaattatac ccactacctc cctgattatc ttcaatgctt acgtctaaat aaacttcccc
    31201 actattattt agcttagcaa caactgttat agtaaaataa cataaaattc acataaatag
    31261 attagggaaa tcaaagcaac ttctaggaat gttttagcag tcacagtgta ctttcccagc
    31321 atcaagccac tataactctg cacataaaaa tggagaagat ggccatcctc ttctccaaat
    31381 attaacttct ttacaaacca actatagttg acaaagaacc taaaatcaat tgataacaca
    31441 aggtcaggtc ggtcaactct ttcaactgaa gccctgtcaa ctcttcccat ttatcaatct
    31501 tgtattggag agaattgcgg tgcagataga gttgctgggc tgttttagtg agaacagcac
    31561 tattttccca aagagagaga atgatttcct gaatctgatc ttgatccaaa atcatctggt
    31621 gtagacattc cttgattggc ttcaagtcca cgagtctttc tcccatactc caaagataga
    31681 gctgagaaaa agtatgaaca ccttggtgac cctgacgcca ccatgtcttg aacaaatccc
    31741 gctcagcttt gattaagtct gatagggctt gatgtcccgt ctgagaccaa acctgaccca
    31801 acatgataga aagacgaagt ccaaagtcat actcaaccgc ttcaatcgta tcacttaaaa
    31861 tatctcttac ataagtgtat ttgtcttgtt gaagcacgaa aacataatcc tgagatccga
    31921 cctgtagcac tgtctgacaa ttcggaaaaa gagtccgcat catatctagc caagaagcca
    31981 gattttcctg ctgaaaataa gaaagatggc aataaaccaa ctgaatcttt ttaaaaactt
    32041 gcggtgcctg tcccttgcct tcaaccagat aggaatacca agggtttagc gaacgagcct
    32101 gctcctgctg ggtcaaaagg gcaaccaact gcttttcacg ctcgctgagc ccagcttcct
    32161 ccagcaaaat ccactgctga gaagctaaag ggagcgtgag atagccctct ttctctactg
    32221 gttggtctga aatccgagcc tcaggaaacc agtcttgtag ttctttttcc ctcatgttct
    32281 agccctccac tttttggatg caccatgaaa ccaaactctc aagacgttcc agattctcag
    32341 tcatatggag atagcccata accgcttcaa atcccgtgga catacgataa gtcacgacat
    32401 ctgcattttt agcctttgtg tggctattgg tattgcggcc acgtttgtag atttcttctt
    32461 ctttttccgt taggacctgc tcctccaaca tgagagcaat caggcgagcc tgagccttgg
    32521 ctgacacata cttggttgct tcttgatgga gtttattggg tttggtcata cctttgagga
    32581 tgaggtgacg gcgaatatac atagaataca ccgcatcccc ctcaaaggct agcgcaatcc
    32641 cgttaatgag attgacatca atcacgtgtc cacctcactc catccttggt atcaaggagc
    32701 ttaattcctt gagtaaccaa ttggtcacgg atttggtctg ctgtctcaaa gtctcgattg
    32761 gcacgcgcct cttggcgttt ttgaatcaag tcttcaatct ctgcatccaa aacttcctca
    32821 acaaagacaa ttccaaaaat ttctaacata tctgcaagag cttgcttgac acttgcatca
    32881 tagttccctg agttgatcca tttggccatt tcaaagacaa ctgtgatacc gttggcagca
    32941 ttaaaatctt catccatagc tgctacaaac ttatctttaa agttttgtaa ctcttgggca
    33001 tccacgtttc ctgtaaatgg ttgttcgtaa gtattcttca gatacttgag attggtctcg
    33061 gcatcgcgaa ctgccttttc cgtgaagttg ataggcttac ggtagtgctg ggtcgcaaag
    33121 aagaaacgaa gtacttgccc atcaagagtt ttaagggcat cgtgtaccgt aatgaagtta
    33181 cccaaggact tagacatttt gacattgtcg atattgacaa agccattgtg catccagtag
    33241 ttagcaaaag ccttgcctgt tttagcttca gattgggcaa tttcattggt gtggtgtgga
    33301 aactctaggt cagctccacc accgtggata tcaatggtat cacctaaaat ctctgtcgac
    33361 atgactgaac actcaatatg ccaacccgga cgtccaggtc cccaaggact atcccaagaa
    33421 atctcacctg gtttggaaga tttccataga gcaaagtcta caggattttc cttacgagcc
    33481 gtttcttcat cggtacgacc tgaagcacct agctccaaat cttccaaggt tttattagcc
    33541 aatttagcat agttgtggga tttttctaca cggaaataga catccccttg actctcatag
    33601 gcaaagcctt tctcgatcaa gtcttccaca aaacggatga tgtctgccat aaactccact
    33661 acacgcggat ggcgagtcgc aggtttcacg cccaaggccg tcacatcctc acgaaaggca
    33721 gcgatgtact tatccgcaac ctcctgaggc gtgatgcctt cttccctggc acggttgata
    33781 atcttatcat ccacatctgt aaaattggaa atataggcaa ccttataccc acggtactca
    33841 aaatagcgac gaatcgtatc aaaagctacc gtcgaacggg cgtttcccac gtggatatag
    33901 ttgtacaccg ttggcccaca aacatacatc ttgatcttgc cgtcctcaat cgggacaaat
    33961 tctcgcaaat cacgagacat ggtgtcatag attttaatca taaatcataa tcaggaaagc
    34021 tgaaatccaa gaacaattag tttcatcact aaaagttcaa gtaaatttca gtccgaatat
    34081 ctctacactt cggaatccct tgctcctttc tcattcagat aaaccacctg agtctgtttg
    34141 acaaagccaa ttttttcata caaacgtttg gcacctacat tgctatcttc cactgcaatc
    34201 tgaaattcct tgtcattttg ctcaattagt tggttgacga gggattttgc taagtagctt
    34261 ccatagcctt ttccacgttc aggttccaat attgctaaac cgtagaagta attcgtatta
    34321 gtcgataaat caaccgtaca agtcccaata acctgaccgt cttttaataa aatatataag
    34381 cgactttctg gatccttcag agcttcagcg acatatctat ccacaacttc tctcgattca
    34441 tgttcctctg aaaatgcctg aaattttaat tgactaattt gatcctgata cgaactatct
    34501 gctaacaaaa cttcaagatg ggaaacattt gctaacggat aaggtcttct atccttacct
    34561 aaccaagttt ctgtctcttc atcctcgatt agtccccagt tactggcaaa gtcaggatga
    34621 ttctctaaaa aaatacgttc tgtctgaaaa gtgactgacc gaatggggaa agaagctatt
    34681 tctctctcaa aactagtaaa caatgcacgc gcaatcccct gacggcgatg acctggatga
    34741 accagtatcg ttacttctac atcttggtca tctgcataga cagttaataa accaacaagt
    34801 tcgccttttt cataataaag gaaaaaggcg ggcatgtttg ggtcaaaatt aagcatgtta
    34861 gagagatagg gatcgcgata ggtaccgtca tagttttggc aacagttaat tacttttttc
    34921 gcttcagata gctcctcttg gcttaacttg tttcttgctt gaatcatata ggtatcctct
    34981 acaaaccaga cgatctgtga ctggcatctt tagcctgctc gagtttattg acataatact
    35041 ctcgtttttc ttcgacttcg tgaatgacag gctcatcttt cttaccatga agacggacaa
    35101 tcttggccgg aataccgaca accgtcacgt cactaggtac atctgctacg acaactgctg
    35161 cagcaccgac cttggcattt tcaccaattt ccacaggccc gataacttgg gcatgggctg
    35221 atatgagggc tccctttcgt acagtcggat ggcgtttgcc acagtctttc cctgttcccc
    35281 cgagagtcac tccgtgatag agaagaacgc ctttttcaac aatcgctgtc tctccaatca
    35341 ccagaccaga accatggtca ataaaaacac ctgaatcaat ctgggctcct ggatgaatct
    35401 caatctgagt ccaaaagcgc caaaactgac tgtacatacg agctaatagt ttgaagccgt
    35461 gcttccagag aaaatgcgag agacggtggg ccgccaaggc cttgacacct ggataagtca
    35521 gcaaaacctc caaagtggtg cgggccgctg gatcattttc ttttacaata tcaatggttt
    35581 cgcgccacca ccccatacat ttctcctttt cttattctga atcttttggt gtttctgtaa
    35641 attctttctt aggtttgtga tccttttgat gacgtgggcg gtgagggcgc tcagactttt
    35701 cacctttttc atcatgctca ggttttggcg gacgaggtag aagagccttc atagaggcat
    35761 cgatacggcc tttttcatca atcttgataa ccttaacatc aacttcatcc ccgatttcta
    35821 ccaaatcctc tacacgattg gtacgagtcc aagccatctc agagatatga acaagggcat
    35881 ctgtcttatc aaagaggtta acaaaggcac caaatttctc gatacgaacg actttagcac
    35941 ggtaaacttc atccactttg gcttcacgaa ccaaaccagc aataatttct ttggcacggt
    36001 taatagcatc ttggtcacta gagtagatag acacatttcc ttcttcgtct atatcaatct
    36061 taacacctgt ttcagcgata atcttgtcga tggtttctcc acccttaccg atgacaatct
    36121 taatcttgtc cacatcaatc ttgatcgtat caattttcgg agcagttgga gccaattctg
    36181 gacgaacttc tggaatggtt gcttcaatga catcaaggat ttcaaaacgc gctttcttgg
    36241 cttgagcaag agcctccgtc aagatttctg cagtaatccc ttgaatcttg atatccattt
    36301 gaagggctgt aatcccatca cgagtacctg caaccttgaa gtccatatct ccaaagtgat
    36361 cttccaaacc ttggatatct gtcaatactg tgtagttatt tccatctgag ataagtccca
    36421 tagcaatacc agctactggc gccttgattg gcacaccacc agccataagg gcaagagttc
    36481 ccgcacagat agaagcttga gatgaagaac cgtttgattc caaaacttct gctactagac
    36541 ggatagcgta tgggaattct tccaagcttg gcaagacttg agcaagagca cgctcaccaa
    36601 gagcaccgtg accgatttca cgacgacctg gcgcaccgta acgacctgtt tcccctacag
    36661 aatattgagg gaagttatag tggtgcataa agcgtttctt gtactctgga tccaaaccat
    36721 caatgatttg agtttctccc atcggagcca aggtcaagac tgaaagagct tgagtttgcc
    36781 cacgagtaaa gagacctgaa ccatgtacac gaggaaggaa gtcaacaacc gcatccaaag
    36841 gacggatttc atcgacctta cgaccatcag gacgcacctt gtcttctgta attaaacgtc
    36901 gcacttctgc gtgttccatt tgttccaaga tttcagccac atcacgcata atacggtcaa
    36961 attcttcgtg gttcgcatat ttttcttcgt aaacggcagt cacttggtct ttcactgctt
    37021 gagttgcagc ttcacgggcc aatttctctt ctacttgaac tgccttttgg aggtcactgt
    37081 tgtaggctgc aatgatttca gcttgcaatt cagcatccac gtgaagcaat tccacttctg
    37141 ctttttcttt accgacagca gcaacgattt cttcttggaa ggtaatcaat tctttgacag
    37201 cttcgtgccc tttaagaagc gcttccaaca tgatttcttc tgacaattct ttggcaccag
    37261 actctaccat gttgatagcg tgcttggttc cagctactgt caattcaaga agagattgct
    37321 ctgcttgttc ttgacttggg ttgatgatga tttggccatc tacatatccc acttgtaccc
    37381 cagcaattgg tccgtcaaat ggaatatctg aaatagacag tgccaaagat gaaccaaaca
    37441 tagcagccat tggtgcagat gcattttcat cataagaaag cactgtattg atgacttgga
    37501 cttcattacg gaaaccttcc gcaaacatag gacgaatcgg acggtcaatc aaacgcgctg
    37561 tcaaggtcgc atctgttgaa ggacgtcctt cacgtttcat aaagccacca ggaaacttcc
    37621 cagccgcata cattttttct tcgtagttga cttggagtgg gaagaaatcc ccagttgcca
    37681 ttttcttaga cataacggca gcagtcaaga cagttgactc accgtaacgt acgacaacag
    37741 atccatttgc ttgcttagca acctgaccag tctctacaat taactcacga cccgcaaaag
    37801 tcgtttgaaa cacttgtttt gccattttaa tccccttttg attgatgaaa ttatacgcct
    37861 tgcctacaaa gatcaagata ccaaggacgt caaaagcaaa gtaaaaatag gaaactgacg
    37921 aagtcttcga tgaagacaag acagtttatc ttttttacac agcttttcgg ccgtgttcaa
    37981 ttactcaaga taccaagccg tcaagcaact caaaggaaga taggaaatcg aacgacggag
    38041 cgactactcc tagggagatt tatctttttc cacagagttg taggcaagtt cagttttcaa
    38101 gatacatcat tagaaaggtt taatactaaa gtatctaaag ctttcacgct aatcgctatc
    38161 gggcgattag ctaaatgctt tactaactct ctcgtcaaat aacatcgatt tgactcactc
    38221 gtgtcgttaa atcttacagt ttaaatgcat tgtattattt aataccttca tctttgtatc
    38281 aagtacgtac agaatttatt ttatcatatt tttcttaaaa agtgaggtct ttaccattaa
    38341 aaaggaacca ttcccctcac ctgagaagaa tggtttgctt ttattatcct agagactggt
    38401 gattaaacaa ggcatgggtt gcttgatgga tgtattttgc tgtatcagca ttattcatcg
    38461 tatagagatg cacaccggca acatcctgag ttaccaagtc cacgatttgg tccactgcat
    38521 aggcaagtcc tgctgctctg agcgactcag ggtcatgctc atacttgtct aagatggctt
    38581 taaatttgcg tggaagatgg atattctcac aagtcttcaa gagtcggaga gcctgatttc
    38641 gattcagaat tggcataatt cctgcatgaa tgggaacatc aatcccagcc aagatacact
    38701 tgtcctgaaa atcatagaag cgctcattgt caaagaagag ctgagttacg aggctcgaac
    38761 agcctgcatc cactttcttc ttaagatttt gaatatctga aatctgattt ggcgaatctg
    38821 gatgctcttc tggatagcaa gctccaataa tatcaaagtg aggggcttgt tccttgataa
    38881 actcaatcaa gtcggttgca tagcggaaat ccttttgtgg ttctacgtct ggaataatat
    38941 ccccacgaag agccaagatt ttctgaaccc caactttgtc caagtcaaca atagtttcag
    39001 caaccttgtc cttagttaga taaatagctg gcaagtgggc aatggtcgga atcgccaagt
    39061 cattttggat aaagtcagcc aaacgaaccg tcgtttcctt gatattaaat ttattattgc
    39121 tggcagttac actgataaaa tggggagcca actcctgcat atcctgcaag gctgaaataa
    39181 tgttaccatt acccacggct gggtttggag ggaacacttc aaatgagagt gacggtgttt
    39241 ggcgtgacat atgtaataac cttttctagt tgatttcttt ttgaacaacc actgtatgga
    39301 gagaaatcca atcttacaat ttctcacgcg cagctttagc tgcttcaaca aggcggatca
    39361 agctttcttt tgtttctggg ataccacgtg ttttcaaacc acagtcaggg ttgatccaaa
    39421 ctttcttgct tggcacttta gcaaggatgg cttcgattgt gttgtcgatt tcgccttcgt
    39481 ttggtacacg aggtgagtgg atatcgtaaa ccccaggtcc cacttctgtt tggaagtttt
    39541 tcgctttgag ttcgtccaag atttcaaggt ttgaacggct ggcttcaaag gaaataacgt
    39601 ctgcatccat gttatcgata gctgggatga tatctgtaaa ttctgagtaa cacatgtgag
    39661 tgtggatttg tgtgtctgac gctactgttg agtgtaccaa gcggaaggca ggaattgccc
    39721 agtcaaggta atcttcgtac cagtcactac gacggagtgg caatttttca cgaagagcag
    39781 cctcatcaat ttggatgatt ttcacaccag cagcttcaag gtcaagcact tcatccttga
    39841 tagcaagggc gatttgaaga gtagaatcct tgatagagat gtcttcacgt gggaatgacc
    39901 agttaaggat ggtaacaggt ccagtcaaca tacctttaac aggtttgttt gtacgacttt
    39961 gtgcatagct agaccattta acagtgatag ggttaagacg agtgacatca ccccagatga
    40021 ttggtggttt taccccacgc ataccgtatg attgtaccca tccattttta gagaagaagt
    40081 atcctgacaa gttttgaccg aagtactcaa ccatgtcatt acgctcaaat tcaccgtgaa
    40141 caaggacatc aaagtcaata tcttcttgcc acttgatcca ttcgtcaatc gtttcagcaa
    40201 ggaaagcatc gtactctttt tgagacaatt cacctttacg gtaagccaaa cgtttggcac
    40261 gaacttcttt tgtttgaggg aatgaaccaa tcgttgttgt tggaagagct ggaagtttga
    40321 aagcttcttc ttggatagct tcacgttctg caaaggctgg caaacgagtg tagtctgcgt
    40381 ctgtcaagcc agcgatacgc gcacgaagtt cagcattttc accaacacgc tcagtcgcaa
    40441 agagttcttt gttggctgca agagcttctg aaccttgacc attgcggata gcatccaagt
    40501 cacggatttc atccaatttt tcaactgcaa aggcaaagtg gttcaagagt gctggttcaa
    40561 attcttcatt agcagttgta aatggcacat gaagaagtga gcaagagctt gtcaaaacga
    40621 tgttttcagc tgggatttgc tcaagaacag ccaagctctt ttcgtagttg ttgcgccaga
    40681 tgtttttacc attgacaata cctacataga gagtcttgtc agctgggaag ccacctttaa
    40741 cgagttcaag agttttctta ccttcaacaa agtcaagacc gatagcatct actggcaagt
    40801 ttacaaggtc agcgtatacg tcacgaacat caccgaaata agtttgaagc aagacttcaa
    40861 gacctttttt gtcagccaag agtttgttgt aaaggttcaa gaagagagct ttttcttcag
    40921 ctgtcaagtc ttttacaaga gccgcttcat ccaattggat gcgagtcgca ccaagttcag
    40981 ccaatttagc aaaaacttct tggtaagcag ccactaagct atctacgaag tcgtctgctt
    41041 tcacgccttc ttcaaagtct gacaattgaa ggaaagtgaa tggacctaca agaacaggac
    41101 gagtgttcaa tccaagttct tttgcttctt ggaactcatc gaaaatcttg tgaccagcca
    41161 attttacttg agtgtctttt tcaaatttag gaacgatgta gtggtagtta gtgttgaacc
    41221 atttcttcat tggaagggcg cgaacgtccc ctttttctcc ctggtaacca cgtcccaaag
    41281 cgaagtagcg ctcaaggtca gacaagtcca agttttgaac ggatgcaggc accacgttga
    41341 aaaggaaagc cgcatctagg aagttatcat agtgagaaaa gtcatttgat ggaatttcag
    41401 tgatgccttt ttctttgaca atgttccagt gtttagcacg caagtctttt gctgctgcta
    41461 aaagttcttc ttctgagatt tcttttctaa agtatttttc agttgtaaat tttaattcac
    41521 ggaattcgcc caaacgaggg aaaccgatga ttgtagttga catgatgtgt cctccaaaat
    41581 ttgttgttga aactatctta acagaaaaga aagcatctgt ataattgtaa aaaattaggc
    41641 tttgatatag tttgaaacta tacctctatt ttagacaaaa gaaaaagact tgagacacat
    41701 gcctcaaatc ccttttataa cttgttttta gctgtatttt agttagaatg ctcaaacgcg
    41761 ttattagtaa ttcttataag tgactatggc ttgttattag aaaagactat aactgattct
    41821 agtcaacttt tcccctgttc aagtcggacg actgctagta tctttcctag actagctagg
    41881 acttttaaga ctgtgtccaa ctgtggacta gtcttacctg tctccatcct agctataaca
    41941 ggctgactca ctccactgag ttcctctagc tttttctgac tgattccttg cttatttctg
    42001 gcttcaatca actcgctcat gatagctact cgcatatcac tttcaaggat ttcctccttg
    42061 ctaaagagct cagatggaca tccttccaat tactcccaat agcactattc ttcatcactt
    42121 aaccctcttt cttttacgtc tatgtatttt taaaaaaatg agcgaattat gattcgatag
    42181 attgaccagc gggtttaaag ttggtgctag cctatttctt aagcgatttt ccttttctag
    42241 gataaagcag atcctgcttg cttaacccca attttccacg atgaatccaa tagtaaatgg
    42301 ttgaaattcc cacgttaacc cctttagcca taaccatcat ttcaggcgaa aatttttggt
    42361 tatgtatagt ggagaatctt ttcctttagt tccttggtca agcttgattt cttgaccgag
    42421 cgcttgcgat tgttttcata agactgttga gcgtagtcgg cagaataaac ctctttgaag
    42481 cgcccttttc caagacattt tcggactgtc ccacgcttga tttcagtgtg gatagtttga
    42541 ggagcttttc caagtagaga ggcaacttct ctatttgatt ttccttcttt tttccatctt
    42601 tcgattaagc gacggctatc gattgtcaaa tgtttacctt ttgtagtata attgtcttgc
    42661 atctctgtgc cttttaatca tttcaatctt aaattggact ttttttactt gggttgtact
    42721 taatctatga ggaagacaag aaaaagaata tcaatcaagt aaagtcacaa agtcacatta
    42781 gctccgagca accattgcaa attgaggtac tcacacaatg attaaaacat ttctctctgc
    42841 cctttcggtc attctctttg ttatccctat cataacttat tcttttttcc catcttctaa
    42901 tcttaacatt tggctatcta cccaacctat cttggcacag atttatgcct tccccttagc
    42961 tactgcaact atggctgcta ttttaagttt cttatttttt ttcctatctt tttacaagaa
    43021 aaataaacaa atacggtttt actctggcat tttgctctta ctatcgctca tattactatt
    43081 attcggaaca gataaaaccc tttcttctgc atcaaataag actaaaacct taaaattagt
    43141 aacttggaac gtcgctaatc aaatagaagc acaacatatt gagcgaattt ttagccattt
    43201 tgacgccgat atggctatat tccctgaact agctaccaat atcagaggtg agcaagaaaa
    43261 ccagagaatc aaactattgt ttcatcaagt tggactttct atggccaact atgatatttt
    43321 cacttctcca cctaccaata gtggaatagc tcctgtgact gtgattgtca agaaaagtta
    43381 tggtttctat acagaagcta aaacttttca tacaacacgg ttcgggacaa ttgtattaca
    43441 ttcgagaaaa caaaatatac cagatatcat tgccttgcat actgctcctc ctctgccagg
    43501 tttaatggaa atctggaagc aagacttaaa catcattcat aatcaattgg cttcaaaata
    43561 tccaaaggct attattgcag gtgattttaa tgcaactatg cgtcatggag cacttgcaaa
    43621 aataagctct catagggacg cattaaatgt actgccacct tttgaaagag gaacttggaa
    43681 tagccaaagt ccaaaacttt ttaatgcaac aatagatcat attttattgc ctaaaaacca
    43741 ctactatgtt aaagatttag acattgtaag ttttcaaaac tctgatcata gatgtatttt
    43801 tacagaaatc acattttaat tattttatat aaaatcaccc ctctagtgtt cataaactag
    43861 agggggaatt tgtatcatac tatcgtttaa cgcacttctg cattgacttt ttcttcgagc
    43921 gatgcttgga ttttttccat atagcgtgcg acttcttcgt ccgttaagct atcttctgga
    43981 ttttggaagg tcaagctata agccattgac ttcataccaa gtcccaattt ctcacctgag
    44041 aagacgtcaa agagtttgat atctgtcaaa cgtttcacgc cggcagcttg gatagcatct
    44101 acaacttctt gatgagtcac ttctgccttg aggagaaggg caacgtcacg gctgactgcc
    44161 gggaatttgg tgatttctac aaatggagtc gctggctgaa gcgcagcttc gatagctgaa
    44221 aggttaagct cagccacata cgtttctgga atatcgtaag ccttggcagt gactggatgc
    44281 acttggccaa ggaaaccaag aacttggtca ccgagtgaaa tcacggctgt acgacctgga
    44341 tgaaggctag cgatttcaga tgttgctgta taggttactt ggagtcccaa acgagtaaat
    44401 agggcttcaa ggattccctt agcatagaag aaatcaactg gaactgctgc tgtttggaaa
    44461 tctttttcag caaccaagcc tgtcaaggca aaggcaaaac tgttgatttc atttggaagt
    44521 tcttcttttg gattacctgt ttgttcaaag acttttccaa tctcgtaaag ggccaagttt
    44581 ttattcttac gagccacgtt gtaggcaacg gtatcaagga tacctgaaat catattttga
    44641 cggaggactg aacgatccac agtcattggc cacatgagtt ccgtaaggtt acttggttga
    44701 gccgtaaact caactgcttt ttcaggagtt gttagagtat aggtgatgat ttctgtcaaa
    44761 cctgctcctt cagcaatagt acgaacttga cggcggagtt tttgtgtggc tgtcaattca
    44821 cctgctgtac catcgtcttt tggtagacta gttggcaagc ggtcataacc atagatacga
    44881 gcaatttctt caaagaggtc agcttcgatt gtgatatccc aacgacgacg tgggactctg
    44941 actgtaaagc tgtctgcatt tccagaaaga ccaaagccaa gacgacggaa gacgtcttct
    45001 acatcagcat aagacagctc agttccgagg acacggttaa catcagcaag ggttgaagaa
    45061 acttctacat ctgaagtatc aagctcaccc gctgaaacga tgcccttacg caccgtcgca
    45121 cctgcaagtt ccgcaatcag gctagctgcc gcatcaaggg cttcattaac tgttgccaca
    45181 ttaattcctt tttcaaagcg agaagatgac tcagaacgaa ggttcaggcg accacttgtc
    45241 ttacggatag atttgccatt gaaaacagca gcttcaagga caacacgact agatttttca
    45301 gagatttctg ttgcttgacc acccatgaca cctgcaaggg ctactggctt gtctgcgaca
    45361 gtgatgacta ggtcattcac gtccaagtca cgttcttcac cgtccaaggt caccaatttt
    45421 tcaccagcac gcgcttcacg cacacggatg tcagtccctt caaagttatc caagtcaaag
    45481 gcatgcattg gttgaccaaa atagagcagg atgtagttgg tcacgtccac tacgttattg
    45541 atgggacgga ttccttcgtt catgagaagg ttttgcaacc attgtggact tggtgcgatg
    45601 gtcacattgt ccaagatacg agctgcatag taaggcgcct tgtctgtctc aatgctgaca
    45661 gaaagggcat ctgccgcagc ttcattagtt tctgttagag taaattcttt aaagttgact
    45721 gccttgtcat agatggctgc cacttcgtga gccactccac acatagaaag ggcatctgca
    45781 cggtttggtg tgatggaaag ttcgatgatt tcatcatcca agtctaggta agaaaagact
    45841 tcctcacctg gcacggcatc ttcaggcaag atttggatgc catctgcgaa ttccttaggc
    45901 acaactgagt cagaaattcc caattcacca agtgaacaga tcattccaag tgactccaaa
    45961 ccacggattt ttcctttttt gattttgtag ttatcagcga tacgagctcc tggaagagcc
    46021 accatgacct tgatcccagc acgcacattt ggggcaccac aaacgatctg acgctcttct
    46081 tcgccaacgt taacctgaca aacatggagg tgagtctctg gcacatcttc gcaagacaag
    46141 acctcaccga cgacaatttt tgagagacca gcagctggtg attcgacacc ttcgacctcg
    46201 attcctgtag ttgacatttt ttcagccaac tcttgtgatg gcacatcaat gtccaccaat
    46261 tcttttaacc atttataaga tataagcata atttagttct ccagaatgac cattgccaca
    46321 ctggttcttt tcctttccta tcatttcaat agaagaatcc tcttcttacc ttaatttctt
    46381 tctcagtaac caatccgtat ctactttttg accaaccata aaatgatgtt ggctaaattt
    46441 ttcaaaacca tatcgattat aaaacgcttg agcttttgta ttatgctccc aaacacctag
    46501 ccaagcccaa gaaaaactat tttttgtagc aagttcaagt gcgaattcaa acagttgctt
    46561 acctagtcca aatccttgga atttttgtag cacatagagg cgttgaattt caaaagcgtc
    46621 ctctaattct ctctcagttt gagcacttcc ccagttgact ttgagaaaac cagctatctc
    46681 ctcctcatgc ataatgaaat aggtttcaga gtcaggattt cccaactcag ttgacaaagt
    46741 tttcagacta taagcctctt caaagtattc ctgtaactgc tcttccgtat tatcatacgc
    46801 aaaggtttca cgaaaggctt gtttggcaat tttagccaac acctcaacat ctgccatttc
    46861 tacttttcta atcattattt aaactgttct gagaagcgga catctccttg gtagaatcca
    46921 cggatatcgt tgattccata acggagcata gctacacgct cttgtccaag accaaaggca
    46981 aaaccagagt atacagtcgc atcgatacca ctcatttcaa ggacacgtgg gtgaaccata
    47041 ccggctccca taatttcgat ccaacctgtt ttcttacata cgttacagcc ttctccacca
    47101 cacttgaagc aagaaacatc cacctcaaca gatggctctg tgaatgggaa gtaagatgga
    47161 cgcaaacgaa tttgacgctc ttcaccaaac attttttgga caatcaactg aagcgttcct
    47221 tgaagatcag ccatagagat atttttccca actaccaagc cttcgatttg gtggaattgg
    47281 tgactgtggg tcgcatcgtc cgtatcgcga cggaagacac gccctggcga gatcatcttc
    47341 aaaggacctt tagaaaaatc atgggcatcc atagcacgcg cctgaactgg agacgtgtgg
    47401 gtacggagca agatttcttc agtgatatag aaagtatcct gcatatcacg agctgggtgg
    47461 tcttttggaa ggttcatacg ttcaaagtta tagtagtctt gctccacttc aaaaccatcc
    47521 acgacttgat aacccatacc gatgaagata tcttcgattt cttcactggt ttgtgtcaaa
    47581 acgtgacggt gaccagtcgc aactggacga cctggaagcg tcacatcgat actctcgcta
    47641 gccagttgag ccgcgacttt cttttcttcc aagagcttag ctgtttcttc aaaagcagct
    47701 gtcaagacat cacgagcttc attgacgtgt ttcccgatga ttggacgcat ctcagcagaa
    47761 acatctttca tccctttgag gatttcagtg agcgaaccct ttttaccaag gacagagaca
    47821 cgcaaatctt gcatctcttt ttcatttcca gcagtaatct gcttcaagct agtcagcgtt
    47881 tcttcgcgaa gcgcttttaa ttgttcttca atagttgaca tatttcctcc atcagtctct
    47941 cgtagataaa aagaaaacca catgccaaaa actccactcg gagcgttgac acgcggtacc
    48001 atccgttttc atctgacaag tcagaccttc atttctaaat ccatgcgcaa gtgaattcac
    48061 ccagctttca tatagagagc ttgcagtcac ggctctcctc cctgatatac ttcccttggg
    48121 ctactagtct ttcagatttc tattcaatta ccacttagtt tatcagattt ttaccattct
    48181 tgcaagacct atcttacttc tgcttgttag cttattctta tctaacttta tagcggattg
    48241 aaataagatg aaaacaaa
//
LOCUS       DAVBOH010000011        45265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOH010000011 DAVBOH010000000
VERSION     DAVBOH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.011"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ873_000659"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ873_000659"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3106973.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ873_000660"
     CDS             complement(1995..2927)
                     /locus_tag="VQ873_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3106974.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ873_000661"
     CDS             complement(2924..3781)
                     /locus_tag="VQ873_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3106975.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ873_000662"
     CDS             complement(3785..5131)
                     /locus_tag="VQ873_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3106976.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ873_000663"
     CDS             complement(5144..5428)
                     /locus_tag="VQ873_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3106977.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ873_000664"
     CDS             complement(5432..7462)
                     /locus_tag="VQ873_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3106978.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ873_000665"
     CDS             7653..8660
                     /locus_tag="VQ873_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3106979.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ873_000666"
     CDS             8663..8863
                     /locus_tag="VQ873_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3106980.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ873_000667"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ873_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3106981.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ873_000668"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ873_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3106982.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ873_000669"
     CDS             complement(9784..11664)
                     /locus_tag="VQ873_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3106983.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ873_000670"
     CDS             complement(11658..12527)
                     /locus_tag="VQ873_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3106984.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ873_000671"
     CDS             complement(12611..15256)
                     /locus_tag="VQ873_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3106985.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ873_000672"
     CDS             complement(15347..16627)
                     /locus_tag="VQ873_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3106986.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ873_000673"
     CDS             16798..18882
                     /locus_tag="VQ873_000673"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3106987.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIDTGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ873_000674"
     CDS             complement(18922..20601)
                     /locus_tag="VQ873_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3106988.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ873_000675"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ873_000675"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3106989.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ873_000676"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ873_000676"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3106990.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ873_000677"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ873_000677"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3106991.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ873_000678"
     CDS             24983..26494
                     /locus_tag="VQ873_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3106992.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ873_000679"
     CDS             26516..27847
                     /locus_tag="VQ873_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3106993.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            27942..28069
                     /locus_tag="VQ873_000680"
                     /pseudo
     CDS             27942..28069
                     /locus_tag="VQ873_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(28252..28542)
                     /locus_tag="VQ873_000681"
     CDS             complement(28252..28542)
                     /locus_tag="VQ873_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3106994.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(28530..28782)
                     /locus_tag="VQ873_000682"
                     /pseudo
     CDS             complement(28530..28782)
                     /locus_tag="VQ873_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            28986..29063
                     /locus_tag="VQ873_000683"
                     /pseudo
     CDS             28986..29063
                     /locus_tag="VQ873_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29181..30065)
                     /locus_tag="VQ873_000684"
     CDS             complement(29181..30065)
                     /locus_tag="VQ873_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3106995.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(30210..31361)
                     /locus_tag="VQ873_000685"
     CDS             complement(30210..31361)
                     /locus_tag="VQ873_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3106996.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(31507..33273)
                     /locus_tag="VQ873_000686"
     CDS             complement(31507..33273)
                     /locus_tag="VQ873_000686"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3106997.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(33330..36446)
                     /locus_tag="VQ873_000687"
     CDS             complement(33330..36446)
                     /locus_tag="VQ873_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3106998.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(36456..38750)
                     /locus_tag="VQ873_000688"
     CDS             complement(36456..38750)
                     /locus_tag="VQ873_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3106999.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(38809..39609)
                     /locus_tag="VQ873_000689"
     CDS             complement(38809..39609)
                     /locus_tag="VQ873_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3107000.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(39606..40379)
                     /locus_tag="VQ873_000690"
     CDS             complement(39606..40379)
                     /locus_tag="VQ873_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3107001.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(40404..40874)
                     /locus_tag="VQ873_000691"
     CDS             complement(40404..40874)
                     /locus_tag="VQ873_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3107002.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(40865..41296)
                     /locus_tag="VQ873_000692"
     CDS             complement(40865..41296)
                     /locus_tag="VQ873_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107003.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(41289..41729)
                     /locus_tag="VQ873_000693"
     CDS             complement(41289..41729)
                     /locus_tag="VQ873_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3107004.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(41741..42379)
                     /locus_tag="VQ873_000694"
     CDS             complement(41741..42379)
                     /locus_tag="VQ873_000694"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3107005.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(42494..43897)
                     /locus_tag="VQ873_000695"
     CDS             complement(42494..43897)
                     /locus_tag="VQ873_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3107006.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            44073..44846
                     /locus_tag="VQ873_000696"
     CDS             44073..44846
                     /locus_tag="VQ873_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3107007.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
BASE COUNT        13590 a         9877 c         7938 g        13860 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagatacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaattg agttatgaag
    27961 ataaagttca gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa
    28021 gatttgtgtg gatgtttctg gtctaaagtc atctgaatct ttgagatgag ctttataaat
    28081 cgcttttttc agtttttgca ctggtgtttc gataaactca aactttttag ccgtggtatt
    28141 gcctgatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aacattttta
    28201 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt actatatttg
    28261 agccacttcg tctttaacgg ctttattcat aagctcttgt aatttttctt tactatcaat
    28321 tacttctgat tttccgttgt aatttattgt aataggtttt aacttaccta atttctcgac
    28381 acgctcagaa atttgatctt ttttgaaggc tgcatatgtt tttcctaaga ttttttcgaa
    28441 aatatattta tcagatagcg gtttgccttc ttcttcagct tggtttttgt attgatttga
    28501 aacataagga acaaatcctt catagtaacc taatgctccc ataagttcaa aagcttgttt
    28561 tctaattcaa accattgcaa ctcagatttc agcttttcag ataaatcctg ctcatccaaa
    28621 taatgacttg aaattagtgc tgaactcgtt tctgtatcct gtacaggctg agcacccata
    28681 ccagcaaaaa aataaactcg ttcctagcaa gaccgaacaa gctcctattg catatttcct
    28741 caaagaaaaa cgctgctttc tctcaaattg aaattctttc atcccatctc ccatcattca
    28801 ttattactgt atattttgta tatcagaaat agtttgtatt cacaaatctt tctagttatt
    28861 cccttatcat tcctaattaa gggagataac atacaataat ttttagttaa atgtatatcg
    28921 atgttttttg tttttcttaa taaacgcaat acaaaaagag cctgttgcca agctctttat
    28981 actcaatgaa aatcaaagag caaactagga aactagccac aggttgctca aaacaccgtt
    29041 ttgaggtagt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    29101 gaactgacga agtcagtaac atctatacgg caagacgacg ctgacgtagt ttgaagagat
    29161 tttcgaagag tattagtcta ttatttcttc tcagcgcgaa gggctgacaa gatttgtgta
    29221 cggatatcat ccacaccatt tggagtattt ggtaaaaaga tggtttgatt tcctttagag
    29281 gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga ggatagacat gatttgttct
    29341 tctgtcatgc caacattggc ttccttgagt tcggtgatag actctgccaa tccatccaca
    29401 atcgccttac gttgttgggc aatccccaca ccatgaaggc ggtctttttc tgcttcggct
    29461 tcagctgcag tgacaatttt aatcttgtca gcttccgcca attcttgtgc tgcgacccgc
    29521 ttacgttgcg ccgcattgat ttcattcata gattgcttaa cttctgcatc tggttcgacc
    29581 ttggtaatca aggttttcac gataatgtag ccgtaagtgg tcatttcttc tgctacttgg
    29641 tgttgaacct caagggcaat ctcatctttt ttctcaaaca attcatccaa ggttaatttt
    29701 ggaacagaag agcgaagagc atcttcgata taagatttaa tctgagattc tggacgtatg
    29761 agtttatagt aagcatctgt cacgctctgc tcgttgacac ggtactgagt cgctacattc
    29821 atcataacga acacattgtc cttggtctta gtctcaacca caatatcact ttgcaacaag
    29881 cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag gcaagcgaat atgaataccg
    29941 ctattagcaa ccttttggta tttcccaaag cgttcaataa tcgccaccga ctgctgacga
    30001 accacataaa ctgtactcag tgtgactatc accaatagga gcacacaaac aatcagaaaa
    30061 atcatgaaaa atattgccat aatggaacct ccacaagtat ttttctagta ttatagcaca
    30121 tttaaagaag gctgtgccgt ttttactgcg atttttcctg aaatgtcaat aattagaggt
    30181 gaattgtcct attgtcgtct aatctcttgc taaaataact ctttataaaa ggcaatcgtt
    30241 tcttctaagg ttggcataaa tggatttcct ggtgcgcagg catcaatcaa ggcattctta
    30301 gaaaggtatt caaagtcgaa atctttttct tcaataccaa gttcagtcaa tttcttagga
    30361 atacctactg tctcagaaag cttctcaatc tcagcaatcg cataatcggc acactcttga
    30421 tctgatttac cttccacatg aaggcccaag gctttggcaa cattgcggaa agcttctggt
    30481 acacgtttag cattttcacg ttctataact ggtagcaaca tggcacagca aacaccatgt
    30541 ggcaaattat atactgcacc gagttggtga gccattgagt gaacataacc aagaccagca
    30601 ttattaaagc tcataccacc aaggaagatg gcattgacca taccttcacg cgcttcaata
    30661 tcatgtccat tttctacagc acgaggaaga tattccttga taagctcaat agcaccaata
    30721 gacagtttct tggttacatc ataagcacca ggtgttacca aagcttcaac agcgtgagtc
    30781 agagcatcca taccagtagc agcagtcaga cctttaggtt tggaaagcat gagttccggg
    30841 tcattaacag agataagagc aaggctattc ttgtcaacca ttaccatctt aaccttgcgt
    30901 tcttcatcag taatcacata gttaatagtg atttctgcag aagttcctgc cgttgtattg
    30961 atagccacaa ctggcaagcc ttttttagca gacttatgaa gcccttcata atcctgtggt
    31021 tttccaccat ttgtagccat gatagaaata caactagctg catcctgtgg agaacccccg
    31081 ccaagactga tgataaaatc acatccatgt tcttgcaaag cagctacccc atctgtgaca
    31141 ttcttacaag tagggtttgg ctctacatcg ctaaagatga catattcgat tccttctgta
    31201 tccagtggtt ttaaagtctt aggtaaaata tcactgcctt cgatgtactt atctgtcacc
    31261 aaaagtgcct ttttatagcc aagttccttg atataaggac ccacttcatt tacaacacct
    31321 tttccaataa ggttgactgc cggaacataa aatgtagcca tataattttc ctcctgcgcc
    31381 tccgcgctat ctatttaaca tcattatatt actttttgta ttcgttttca attatttgtg
    31441 aattgtttaa caaatctttt taaaaggata ggagggacgt aagttcacct cctatataaa
    31501 caagttttat ttatgtagtg gtcccaacaa ctgacatgca cgatagtctg ctgattctag
    31561 atcttctgtt ccaaataagg accaattttt aggtctaaag atatcttcct caggtacatt
    31621 atgcatattg acaggaattc tcaacataga agccaaggta atcaagtctg ctccaatgtg
    31681 tccatatgtt atggctccgt gattagctcc ccaattattc atgacgtcat agacagactt
    31741 gaaagcacct tttcctgtca aacgtggagc aaaccaagta gttggccatc ctggatctgt
    31801 acgattatct aaagtatggt gaacatcttc aggaagttca agtgtataac cttctgcaat
    31861 ttgtagcact ggaccaaccc cttttagaag attgagacgt accattgtta ctggcatatc
    31921 ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg aagtattcgc ggtttgctgg
    31981 tgggaagtct gtattttcaa gcatagcctg cacttcactt tcatccaact cccagaatgg
    32041 tttcataaca ggtttgccat ctcgagtagc ttgacctgta ccatctaatg tacaagaacc
    32101 agagttgatt agatgtaaga agccagctgc agcacgaccc tctaaagtat atcctgttac
    32161 acgttcaaca gcctctggac tccaataagt acgcacatca gcaaagattt gtggagtatt
    32221 tgttaataga taattaaaga gcatagacac accatttagt gaatcattct ctgtcgcaaa
    32281 tacaaatggt tttcgaatac cattccagtc aaactgagta ttgaggaaag tttccataaa
    32341 atctccattt ggaaaatggt ctgtccactg acgttgacct tggaaaccag ctactaaagc
    32401 atggtgacca actgcttctt cctcaaaacc aagttcagca agtcttgggt taccaaccat
    32461 taagtcacgt ccaatcatga acatcttaat aacaaattcc cattgtctat ctttttcttc
    32521 acggcttaaa acaaggtctt cacggttatg gtcgaatcct tcttttacgt tttctttcac
    32581 ccatttgagc gcacgttcga actcttcagg gtcgtaaata ccacggtcca tacggcgtgt
    32641 gaactccgtc atatctaccg attcatttcg cattcctaag tattcttgga agaaatccgg
    32701 atttacaata gaaccaccaa tccccatcga aacactaccc attgataggt aagcagtgtc
    32761 tctcatcaag ccagttgcaa gagctgcccg cgcataacgt aaaagttttt ctttgacatc
    32821 ttctggaata gctgtatcat tagcttcctg aacatctcta ccataaatcc caaaggctgg
    32881 aatccctttt tgagtatgtg aagctagtac agctgcaaga tagacagctc ctgggcgttc
    32941 tgtcccatta aatccccaaa tagcatgagg aatatctgga gacatatcca tagtttcact
    33001 accataacac cagcatggtg taactgtaat tgttgcgcaa acatttgatt ttttgaacaa
    33061 ctcatgggaa gctgcagcct ctggtacacg gccaatagta gatggagaaa tcacgcattc
    33121 cacaggttcc ccatctggat atttcaatgt gcttgaaatc aaatctgcca cacttttagc
    33181 catgttcatt gtttgtactt caagtgattc gcgtacacct tgacgacgac catcaatagt
    33241 cggacgaatc ccaatacgtg gatgttgaat catactattt tcctcttatt tttctgtttc
    33301 tttcatacta ccgatgataa tttttaaaat tacttataag tataaacctc tacctctgcc
    33361 aaacttaaag gaattcctgc gtttctcaaa gaaattctaa ccttttttcc cttcagccct
    33421 tttaagtcta tggatagatt attgctttct aaactgtcaa tatgttgttt aaaaacttca
    33481 tgattatttg aatcatatat aataatatca aaatttgata atctctgaat ttcagcatct
    33541 gttctattat aaataattaa cttttctaat tcttcggttt gtgctaaatc tatctcccac
    33601 catgaaggag aatctccttt ggtatgagtc actgaatgat gaccataatc tccgttttta
    33661 tttccatcaa ctgctagacg agaaaaacca ttgtaatccg ttgaactctg tcgagtttct
    33721 ttggttaatg caatattaga aagtttcttc ggagttctct ttgaaccata gacttcaact
    33781 tccgctaaac ttaacggaat agctgctgat tttaattcta ttttgactag cttagcccct
    33841 acagaaggta cttttaaaga taacaaacca tcaactactt tatcaaaatg tcttctaaaa
    33901 acttcttctc ctgatgaaga tagaaaaata acatcaaaat tagataaacg ctgaggttcg
    33961 gcatctgttc tattataaat atcaacttta gaaaccgtaa actcttctcc cagatcgacc
    34021 tgccaccaag cgttagaatc tgccttagta tgagtcaccg aatgatgtcc gtaatctcca
    34081 tctttattac catcaactgc taaagcagct acaccctcat aattggttga actttgagta
    34141 gctaccttat ttgtagagac tactttatct tctgttattt tatctatatc ctcttcagat
    34201 tgcttaccat ctgattctct aaaaacctct acttctgcta aactcaaagg cactccactc
    34261 gttagtaatt taactttaat ataccttgct cctttttctt tgaaatctag actaacagat
    34321 tcacccgaca aattattaac atgtttctta gcaacttcgt ttctattatt gtcatataga
    34381 atcacatcaa aattagatag acgttgagtc tcagcatctg tgcgattata aattttaaca
    34441 agcccaactt tatccatttt tttcaaatcg acttcccacc aagagggatt atctgcccta
    34501 gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt taccatccac agctctatta
    34561 gggtctccat tgtaatctac agaactttgt gttgttggtt ttgcatatgc tatattcaaa
    34621 ttaccatcat taaatttatc tggtgttggg aaagggactg ggcctgtccc ttcagtattt
    34681 atagacatct ctaccattcc attatgatta accgtaatgg tataaacatg ggtattctca
    34741 tcccaatttt ctgtataagt ataatgattt ttatcgccac ttatatttat ctgaggttta
    34801 tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa agtcattatc tacaggattg
    34861 atggaataat ttttgcttat ccagttcgct aactctaatt cttctttctt ccaacttttt
    34921 gatgcatcaa aatttcctga taatgcccac atagctgtct tatctgtcct gtaattgttc
    34981 aataaaatat gtaaattatt tggattttct ttaacaacag cgtaagtatg tggcgtcaaa
    35041 tctaacgata acgactttgt attattagta tacataggca acattacttg ctgattttta
    35101 ttgatattag cattactatt ataaatatac caggaattac ctacacgctg agcataccca
    35161 tctccttcat aaagttttgg ataaagcgag tttaaatagt tgactttact agacaattcc
    35221 tcactatttt tagtcaaaat ttttgcatta gggaatatag atgaaatctt ttccttatca
    35281 attttctcat gtattacagg aagaatatga tatctcccat tattatataa aggcattgtt
    35341 tcatcattcg aataaagtcc ttgataaaat ccgtttaatg aactaatcct accttctcca
    35401 ttccaaaata cagcttttgt tctatttaca acttcttcct tacttggagc tggattttgt
    35461 atagcatgtc taaagaaagg aataatacct ttagtaaatg ctggagttgg tacatcattt
    35521 gtcataaatg tatacgcggc acattcaaaa ttataaactg tgcctccccc agtatataca
    35581 ttcatcattt ccatagcaat cattgattct ggttccgatg cataggatct catatcccta
    35641 gctcttccag tttcaaatgt gtttgtataa tgtttttccc accatttcca tgtatctgtt
    35701 gatgagcccc agttatcaca taagccactc aaccaaaatc cactaacgat agaatctgta
    35761 cccgcatcat ctcttattgg cgtattttta gttgccaaca ccaaattttt atgatatttt
    35821 tgactcgctt caaagaatgt cggatcattc ataatagttt cccagaacca tttttcatga
    35881 tcatgccaga taaaatgcgc tccatatttg gcacaaactt ccaaatattt agcactatgc
    35941 ggagctaact ggttattgta aatccaataa ttctcaatat ttaaaacacc ttttaacaca
    36001 ctatactttt ggaattgttc atctaaccac tctggaggaa ctgtattacg ctctccagcc
    36061 gacataataa ccaagaaaac tggaatgttt agactttgag cttcctccaa catcttgaca
    36121 taccattctc tcaattcttt cgtatctcgt ggaatacaac ttgttggttt acagactttt
    36181 gcaggatgaa gttcaatcgc tgcatatggt tttacatctt caggaatagc ttcccatgct
    36241 cccttcaatg tgttccccca ccataatccg ttaccattat cattgccata caacggagaa
    36301 agcaacaatg gcgattcatt attaatcgtc gttctcattt gaacacgatt atcagcctta
    36361 actcctgcta acaatccaaa acataacatc ccaatacata caaacagtat tgtgattaat
    36421 tttcttttta ttttttcttt attcatgact tatacctaaa aatttaactc aataattttt
    36481 tctgaattaa ataccaattc aatattttgt acatcagtat ttttgccata tattcttact
    36541 cttacttttt gatctttgtt tcctccttcc aattttagga atgttatatc cccatttttc
    36601 caagcaaacg ataccttata tcctcctctt actctgaaac ctttcacttc tccttctgac
    36661 caagcagaag gtaaagctgg aattagtgat aaccaattat gatggctctg tactaataat
    36721 tcacaaattc cactcaccaa acctaaatta ccatcaattt gaaatggtgg atggtcaaga
    36781 aataaattgc caagagtcgc attatttaac aaaccattaa tctggttata agcaggttca
    36841 ccttgatata gtctcgcaaa aaaatgaatc agccatgcag cactccaacc tgtttgtgta
    36901 ctagcatgca aaccacttac taaccaatta ttaatcgctt gctccctctc ctgtgaagat
    36961 aaaaagttag cgtttgataa tctcctattg atagtgattt tagctgcttc tgctaattcc
    37021 ggagttttat gaatatcaat ctcattataa ggataaagcc caaatagagg tgaaatgtgt
    37081 ctatgcccag gctctacttc ttcataatct tctaaccatt cttggatttg cccattacta
    37141 cctatttttg ttttaggtag tttctttttt aactccttca cacgactaat aaaatccgaa
    37201 ttgtctccta attgttttgc aattccaatg catgaatcac aaaaatatct taaaatttga
    37261 ttatcaattg tagatgatag acaagcattt ccttcaatac cattttttaa gcgatattta
    37321 ttttccggtg agacacttgg acctgtcatc aagtagccat ccacctcaaa taaataatct
    37381 tcaaagaaaa gaaatgcttc ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct
    37441 tggaaatata aatagtgttc ccaaatatga gtacataacc atggaatagt taatacccaa
    37501 attgcagccc ccatggcatg agattgggga gccgtatcgc caaaaccatc cgtattatga
    37561 tgtgctgtaa aacctctagc tccatacatt ttcttagcgg ttagtcttcc cggttctctc
    37621 attctttcga gcatatcaaa taatggatat tctacttctg gtaaatcaca tggacctacc
    37681 atccaataat tcatttgagt attaatatta atcgtatatt tagaacccca aattggattt
    37741 aattcatcac accatattcc ttgaagattg gcaggtaaac cattcggttg actagacgat
    37801 attaacagat atcttccata atgaaataac aagttagtca agtagttact atacttttta
    37861 gtgttttcaa gaagtagatt cgttggaatg ctaagacaac ctttactata gtctagttta
    37921 aaatcaactc tattaaattg ctcctgatat ttttttacat gttcatcttt ttctgtaaag
    37981 taatcaatac tactaaattc tccctgaaga gaagaaatat ctatatttcc ccaataatcc
    38041 gtcattgatt tgagataaag aaatacctct gtagcattcc gaataactat tgtctctccc
    38101 aatacactta cttcaccatc cgtaacctta gaatgacata ctactttaaa ctgaacacct
    38161 tttctacctc cagcagaggc cgacattaaa attgtacttg aatccagttt agatacttcg
    38221 tcattaaacc gtttatttct acccaaatta atgtttaaat ttaatgtgtt ttgaactgat
    38281 gacactatac ggcaacataa aatattctta ttaaaactcg taaaatattc tctttttatt
    38341 tgtaaattac aactattagg ctcaaacaca acattagaaa tagctgtatc taaatctagc
    38401 tctctttcat acaatgaaag agcacaagac tgaatatcta tatgctcaat gtaaagttcc
    38461 ccaagtaatt catagtggct ttgatctctt ggggtagcaa acattgttaa ctttatcaat
    38521 tcttcggctt tctgaatttc tccatctaaa agatattccc gaattttttt aagatgcaat
    38581 agtgagtctg gattatttct atctgacttt cctctatacc aaatagtctc atcgtttagt
    38641 tgaatacatt cttttgtagc tgaaccataa atcataccac ctaaatgacc gttcccaatc
    38701 ggcaaggctt cattccaatt tgcggcagct ttcttatacc ataatttcac tctttacctc
    38761 tcttccaaaa tggaggtgat atcccaaata ccacctccac actttctact acttcaaaat
    38821 tcctaaaaca actaggataa ctccaatagc cataacacta aagattagta caaccggatt
    38881 ctttcctttt ctaattaatt tacacattaa taaagtcaaa gccataggga taaatcctgg
    38941 aattaatttt gtaatcattt cttgaacaga aataacaagt tccccctgct taaattctaa
    39001 tccaaaatta ataccaacca ttgatggaat caaaccaccc actagtacta gccctaatgc
    39061 tgtcgccata ctcgtaacgc gattcaatgt tccttttgta ttattttctt ggataagact
    39121 agaaccctta gtatacccat atttcaaacc gaaatattta acaggaatat taataatatt
    39181 aaacaatatt aaggcgataa agatacctaa agcaccgccg tctttagaat aagacgcacc
    39241 aatactaaaa cagataggaa ctagtgtcag ccagaacaaa ctatctccta gaccagccag
    39301 tggccccatc aagccaactt taataccagt aattgaagct gcaccttcat ttccttcttg
    39361 ttcttccata gcggaagtaa ctccaagaat aaatggtgcc gctgtttgat gagtattgaa
    39421 aaactcaagg tgacgtttca ttgcaggaga agctgaatct ttgtctgggt atagtttttt
    39481 caatactgga agaattgtat atagaaaacc taggttctgc attctctcat agttccatga
    39541 agaaccatac ataaaacttc gtttgaaaac ttttttaagt tcaactttag ttactttatt
    39601 attcatcata gatcaagatc ctcctcaaca tcactacttg aagttgtttc ttgtggttta
    39661 cttccaatca tatcgtagaa gtatgctacc gcaataccaa ctagtgagat cccaatggtt
    39721 gacattcctc catacacaga acaaatgaat ccaatcaaca agaataccca catatttttc
    39781 ttgagcatca tatttaaaag cataccaaaa ccaattgaag gtagtaaagc acctgcagag
    39841 ttaagtccct gcataacgat tggtggaacc ttagcaaaca agtctgccac atattcccct
    39901 ccaagcataa tagctaggaa aattggtaca attttaaata acgtgattaa aaccaaactt
    39961 gaataatgat aaaaaccgat ctttgaataa tctccgtttt tagcatcatt atcagctttt
    40021 ttcacaaaat aaacatctaa agtttttgca agaacatcca actgttgggt agcaactgca
    40081 attggaactg ctatagcgat accagcagtt tctccttgac cagataaaat accaaatgca
    40141 gtaccaataa tcgcacctga aatagtatct ggtggagtgt aacctccaat acctgttaca
    40201 ccgagccaag ttaattcaag agctgaacca ataagaacac cttgggtgaa atctcctaag
    40261 actaagccaa ccattgcact tgtaactaag ggacggtgaa tcataaataa cggtccatta
    40321 tagtcaatag tggcaataat cccaactaat gtcaccagta atgcttgtgt gaatagcata
    40381 tactgtacct ccttaaatta tttttataaa aatttttcca acattgtaac tttatcatta
    40441 ggaaccattt gaatttcaac tctcgttccc ttatcaacta ttttcttaaa ataatatttg
    40501 tcttcttcac ctagagctac acctcccgtt accttttcat tttcctccgt tttactcatc
    40561 tgtcctacat tgaggtactc caattttaaa tttccttcaa tagaatcata cacatctttt
    40621 ggatttgtat atatcagcat tgttctcttt tttattggca cagagtttaa aacttccaca
    40681 aaccgtttta cactaaagaa aacaattttt aaacctaccg gtgcagaaat ctttaaaata
    40741 gattgtcgtg ttttatcttc tgagatgcga tcattaacaa tgataacttg ctcaatatca
    40801 tactttttta gccacgtagt gacaacttga ccatgtacca gacggtcatc aatacgaaca
    40861 aactctatag acataaatcc tcttcctcct ctacgttaag ttgttgttta acattaaaca
    40921 aactattttg agcattttga acaatttctt ctaaattgat ttttgaatca taacttgata
    40981 ttaattccac taggagaggg atattaaacc ctgttacaat atcaactgaa tccaaattta
    41041 aaaaccgtga caaagccaca ttattaggac ttcctccaat caagtcagtc aaaacgataa
    41101 cctcttgatt tgagtctaac agttcattta cttgattttt aaaataatgt tcaaactcta
    41161 caatattctc tccaggcatc aaacctaatg tcctaactct atcatttgtt gtctcaccaa
    41221 caaacatttc tgcggtcatg agagctccgc tagcaaaatt accatgactg gcaactaaaa
    41281 ttcctctatt aaacattttc tctttcaaca actactcctt tcttaaggat aatattagca
    41341 taaagtgaag tttctcctgt agcaacaata gcataagctt tcttactacg ttcataaaag
    41401 tcttctcttc taagataagt aatcgtttta agatctgtac catgaccttc aatcatctgt
    41461 ctataggtac cccatatctt aggaatatca tcacccgaaa caacgttcat aaactgaatt
    41521 gaactatcga cgtaactatc taatggcatt aaatacagaa tggaatctaa taattctgga
    41581 atatttacac catcacaacg aattagctta tttgcacatg aggcagaagg ataattcgcg
    41641 tcagctaata ctatttcatc tccatgtccc atttccatta aagtcttcaa taaatctgga
    41701 gaaatatttt tcggtatatg ttttaacatt aatatcctcc ctattttctc tgaccgtatg
    41761 ttttaaattt ttctgccatc aattccatct cctcatcagg aagaactact ggctctccaa
    41821 aattcttagc taaacaataa atttttgcac aatattcaac ttcttcaaca atattaaatg
    41881 cattcaataa attttgtgca cctgctaaaa ttccatgatt cgctagtaaa actgctctac
    41941 gaccttccat tgctttagct gcattcacag ccaattcttt cgtgccatat gttgcatact
    42001 cagctacccg aacatctttc cctgccactg caatcatata atgactcgct ggaagtggtt
    42061 ctctgagaca agctaatact gttgcataag ttgtatgagc atggataatt gcatcgatat
    42121 catcacgagt ttgatattga atcaaatgca tataccattc gctagatggc aagcgttctc
    42181 cctctacaac atttccatta atatccatca ctacaatatc ggattctttg atttcaaaga
    42241 aatcaatacc cgacggggta attgccatca attgtttttc acgatcgaaa acgctgagat
    42301 tcccacctgt tcctttcgtc aaatctgttt ctactagctt cttaccatat ttaattaatt
    42361 cttgttttac atctgacatc cttgtcctcc tcatatcaaa acactaaata tttttcaatt
    42421 caccaattat ccccccttcc tgcacaaaag ctaagaaggg ggagggaggc aaatttacaa
    42481 actctcaatc tttttaattc ttttgggagt aataactctc taattgtaga aactcctcaa
    42541 taacatggtg agcctcttcc atccctttta attgtcccat agctatgagc tgcacaacaa
    42601 tattccccac agctgtagcc tcagtcaaac ctgtaagaac ctctttacca gttctatcag
    42661 caatcatttg gttaaagtaa ctggctctag cacctcctcc aatcacatat atcctcttat
    42721 aaaccttatg agttagttct tctagtaact ctatcgcttt cctatacgtt tcagctaggc
    42781 tttcataaac aatcttaaat agttgtccat ctgtccactc tctagtttca tgatgataag
    42841 ctagatattc tgtcaaagtc ttgtgcatat cagattctgt tgcaaattca gttgattcag
    42901 tatcaatcag aggaagattt tctttttctt tctccaccat tgtcctaata tcatcaaaag
    42961 aataggcttt ccctcttcgt tcaaatgaac gtcttagttc ctctatgatc cacaaccctg
    43021 tacaattctt cagaaatgta atcactccat ctttaccgac ttcatttgta aatccataac
    43081 tgaaggattc ggtagtaaga agcggtgaag taagttccac tccaaccaaa gaccaagtac
    43141 ctgatgaaat aaataaacta ccttctgtct taggtactga gacaatcgcg cttgctgtat
    43201 catgactaca aacattcaca acaggaatat cgcctaaacc atactccttt tttatccttc
    43261 caagaacatt tccctctgaa acaatctcag gaagtaaaga tgaatccaat tcaaatagtt
    43321 ttaagatatt ctgattccag ttttgactcc taggatcaaa taattgagtt gttgaagcaa
    43381 tgcttttttc tgtagcaaac ttacctgtca agagataatt aaacaaatct ggcattaaaa
    43441 gaatcttatt ggtcttatag aaagagtcag gagattcttg acgtgcctta aagagttgaa
    43501 acaaggtatt tatctccata atctgatttc ctgtctctga atacagtttt tctaattcag
    43561 tcatttcaga tatttccttt aacactccct ttgttctttc atcacgataa tgaacaggtt
    43621 gtaataacag cttaccttca ttatcaatca gtccaaaatc aactccccat gtgtcaatac
    43681 cgatagataa aatcttgtaa ctagtattag ccaagcggat actttcaaga attttagcta
    43741 gtagaaagtc aatatcccaa gataaatgcc cttttactct aataggtaga ttagaaaagc
    43801 gatttatttc ttccattact agtttatttt cagaaaggta accaacgatt gctcttccag
    43861 aagtcgcacc taaatctatt gctaaaaccg cttccatttt tcttctctct tcgtccttga
    43921 ttaactttat tataatcccc acgttttatt ttttcaatat gtgaacgctt acttgaataa
    43981 tgttcaaatg ttaacccaat attcataaaa ataattcaaa ttcctccaat ttgtgctata
    44041 atatagttga aatgataaat taggaggagc ttatgataaa agatgaacgt gtacttgaat
    44101 tgattgaaat tattaaaaag aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt
    44161 tctccagcac aagtacctta cgtcgtgatt taattttctt agaaaatcaa ggtcttatca
    44221 aaagaaagca cggatacgtg accctgtcct ctatgaacac aattgaactt tctcatcaaa
    44281 tacgggaagg agaaagtact aggcaaaaaa gactaatcgc tagtctcgct aaagacttta
    44341 ttcggtctgg tatgtgtgtt tatctggatt ccagtactac tgtctacgaa ctttgtccct
    44401 atctttctga acttgataat ttgattattt ttacaaatgg tttacatact gcacaaaccc
    44461 tatctgaaac tgttaaagat agctccaaaa tctttatcac atctggcgag gtcaaacatc
    44521 aatcctgttc cgtggtcaac tatgataagg aaaattcttt attagatcat tttaatatcg
    44581 atttagcatt ttgttcagca agaggtattg atgaccaata tgtttatgaa gcttctctca
    44641 gccaagctat ttcaaaaaag aatattattg acaaagccca tgaaaccatc ttactgattg
    44701 atagttctaa attttacaag actggatttt ttaaaattaa tcccctctcc aaatacacaa
    44761 cctttatttc agacaccgtg ccagatcaaa aattattaga cgcagtcgaa ttatttgatg
    44821 gagaatgggt ttctgatatt caatgaaaat caaataggaa gctagtctca gcttgctcaa
    44881 agtacagatt tgaaaactga tgaagtcagc tcgaaacact gttttgaggt tgtagataga
    44941 actgatgaag tcagtcacat atatacggaa agacgaagct gacatgatgt gaagagattt
    45001 tcgaagagta ttcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt
    45061 ttctcagcaa ccctaaaaac agaggctgga caaaaactca atttcaggag aaaatggagt
    45121 aaaccttccc acaataaaac gcatagtatc aagtttttgc acacctgata ttatgcgttt
    45181 ttctgatttt aaagactttg tcgcctagac cctatatttc aagaattaag tgaccttgat
    45241 gatctaaatg tattgtggta tacta
//
LOCUS       DAVBOH010000012        44507 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOH010000012 DAVBOH010000000
VERSION     DAVBOH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.012"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..220
                     /locus_tag="VQ873_000697"
     CDS             <1..220
                     /locus_tag="VQ873_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107008.1"
                     /translation="SVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTW
                     AHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(255..1052)
                     /locus_tag="VQ873_000698"
                     /pseudo
     CDS             complement(255..1052)
                     /locus_tag="VQ873_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1317..1553
                     /locus_tag="VQ873_000699"
     CDS             1317..1553
                     /locus_tag="VQ873_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3107009.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1784..3070
                     /locus_tag="VQ873_000700"
     CDS             1784..3070
                     /locus_tag="VQ873_000700"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3107010.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3302..4450)
                     /locus_tag="VQ873_000701"
     CDS             complement(3302..4450)
                     /locus_tag="VQ873_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3107011.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4625..5437)
                     /locus_tag="VQ873_000702"
     CDS             complement(4625..5437)
                     /locus_tag="VQ873_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3107012.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5475..5855)
                     /locus_tag="VQ873_000703"
                     /pseudo
     CDS             complement(5475..5855)
                     /locus_tag="VQ873_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5868..6131)
                     /locus_tag="VQ873_000704"
     CDS             complement(5868..6131)
                     /locus_tag="VQ873_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3107013.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6131..6364)
                     /locus_tag="VQ873_000705"
     CDS             complement(6131..6364)
                     /locus_tag="VQ873_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107014.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6364..6732)
                     /locus_tag="VQ873_000706"
     CDS             complement(6364..6732)
                     /locus_tag="VQ873_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107015.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7017..7163
                     /locus_tag="VQ873_000707"
     CDS             7017..7163
                     /locus_tag="VQ873_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107016.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7207..7581
                     /locus_tag="VQ873_000708"
     CDS             7207..7581
                     /locus_tag="VQ873_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107017.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7574..7777
                     /locus_tag="VQ873_000709"
     CDS             7574..7777
                     /locus_tag="VQ873_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3107018.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7794..7991
                     /locus_tag="VQ873_000710"
     CDS             7794..7991
                     /locus_tag="VQ873_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107019.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8002..8163
                     /locus_tag="VQ873_000711"
     CDS             8002..8163
                     /locus_tag="VQ873_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107020.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8158..8583)
                     /locus_tag="VQ873_000712"
     CDS             complement(8158..8583)
                     /locus_tag="VQ873_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107021.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8637..9350
                     /locus_tag="VQ873_000713"
     CDS             8637..9350
                     /locus_tag="VQ873_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3107022.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9363..9620
                     /locus_tag="VQ873_000714"
     CDS             9363..9620
                     /locus_tag="VQ873_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3107023.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9706..10026
                     /locus_tag="VQ873_000715"
     CDS             9706..10026
                     /locus_tag="VQ873_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107024.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10042..10338
                     /locus_tag="VQ873_000716"
     CDS             10042..10338
                     /locus_tag="VQ873_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107025.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10331..11158
                     /locus_tag="VQ873_000717"
     CDS             10331..11158
                     /locus_tag="VQ873_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3107026.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11146..11304
                     /locus_tag="VQ873_000718"
     CDS             11146..11304
                     /locus_tag="VQ873_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107027.1"
                     /translation="MGILELIEQFEIDYYPLSYEKKTLLADQPIHPVVACLSEMASWH
                     ECGGRLVW"
     gene            11298..12068
                     /locus_tag="VQ873_000719"
     CDS             11298..12068
                     /locus_tag="VQ873_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3107028.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12083..12277
                     /locus_tag="VQ873_000720"
     CDS             12083..12277
                     /locus_tag="VQ873_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107029.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12277..12504
                     /locus_tag="VQ873_000721"
     CDS             12277..12504
                     /locus_tag="VQ873_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107030.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12631..12798
                     /locus_tag="VQ873_000722"
     CDS             12631..12798
                     /locus_tag="VQ873_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107031.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12785..12994
                     /locus_tag="VQ873_000723"
     CDS             12785..12994
                     /locus_tag="VQ873_000723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107032.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12966..13295
                     /locus_tag="VQ873_000724"
     CDS             12966..13295
                     /locus_tag="VQ873_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107033.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13285..13710
                     /locus_tag="VQ873_000725"
     CDS             13285..13710
                     /locus_tag="VQ873_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3107034.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13710..14224
                     /locus_tag="VQ873_000726"
                     /pseudo
     CDS             13710..14224
                     /locus_tag="VQ873_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14221..14610
                     /locus_tag="VQ873_000727"
     CDS             14221..14610
                     /locus_tag="VQ873_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107035.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14610..14846
                     /locus_tag="VQ873_000728"
     CDS             14610..14846
                     /locus_tag="VQ873_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3107036.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKKLDWLIEEMEHE"
     gene            14843..15001
                     /locus_tag="VQ873_000729"
     CDS             14843..15001
                     /locus_tag="VQ873_000729"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107037.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15213..15614
                     /locus_tag="VQ873_000730"
     CDS             15213..15614
                     /locus_tag="VQ873_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3107038.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15803..16345
                     /locus_tag="VQ873_000731"
     CDS             15803..16345
                     /locus_tag="VQ873_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3107039.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16509..16700
                     /locus_tag="VQ873_000732"
     CDS             16509..16700
                     /locus_tag="VQ873_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107040.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16820..17140
                     /locus_tag="VQ873_000733"
     CDS             16820..17140
                     /locus_tag="VQ873_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3107041.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17278..17670
                     /locus_tag="VQ873_000734"
     CDS             17278..17670
                     /locus_tag="VQ873_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3107042.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17663..19393
                     /locus_tag="VQ873_000735"
     CDS             17663..19393
                     /locus_tag="VQ873_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3107043.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19401..19619
                     /locus_tag="VQ873_000736"
     CDS             19401..19619
                     /locus_tag="VQ873_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107044.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19637..20839
                     /locus_tag="VQ873_000737"
     CDS             19637..20839
                     /locus_tag="VQ873_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3107045.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20823..21398
                     /locus_tag="VQ873_000738"
     CDS             20823..21398
                     /locus_tag="VQ873_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3107046.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21395..22567
                     /locus_tag="VQ873_000739"
     CDS             21395..22567
                     /locus_tag="VQ873_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3107047.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22579..22869
                     /locus_tag="VQ873_000740"
     CDS             22579..22869
                     /locus_tag="VQ873_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107048.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22872..23153
                     /locus_tag="VQ873_000741"
     CDS             22872..23153
                     /locus_tag="VQ873_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3107049.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23140..23439
                     /locus_tag="VQ873_000742"
     CDS             23140..23439
                     /locus_tag="VQ873_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3107050.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23436..23783
                     /locus_tag="VQ873_000743"
     CDS             23436..23783
                     /locus_tag="VQ873_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3107051.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23780..24103
                     /locus_tag="VQ873_000744"
     CDS             23780..24103
                     /locus_tag="VQ873_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107052.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24115..24693
                     /locus_tag="VQ873_000745"
     CDS             24115..24693
                     /locus_tag="VQ873_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3107053.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24705..25124
                     /locus_tag="VQ873_000746"
     CDS             24705..25124
                     /locus_tag="VQ873_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107054.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25402..28161
                     /locus_tag="VQ873_000747"
     CDS             25402..28161
                     /locus_tag="VQ873_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3107055.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28158..28880
                     /locus_tag="VQ873_000748"
     CDS             28158..28880
                     /locus_tag="VQ873_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3107056.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28881..32102
                     /locus_tag="VQ873_000749"
     CDS             28881..32102
                     /locus_tag="VQ873_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3107057.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            34098..35480
                     /locus_tag="VQ873_000750"
                     /pseudo
     CDS             34098..35480
                     /locus_tag="VQ873_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35461..35664
                     /locus_tag="VQ873_000751"
     CDS             35461..35664
                     /locus_tag="VQ873_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107058.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35667..36019
                     /locus_tag="VQ873_000752"
                     /pseudo
     CDS             35667..36019
                     /locus_tag="VQ873_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36029..36445
                     /locus_tag="VQ873_000753"
     CDS             36029..36445
                     /locus_tag="VQ873_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3107059.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36449..36784
                     /locus_tag="VQ873_000754"
     CDS             36449..36784
                     /locus_tag="VQ873_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3107060.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36784..37740
                     /locus_tag="VQ873_000755"
     CDS             36784..37740
                     /locus_tag="VQ873_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3107061.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(38010..38189)
                     /locus_tag="VQ873_000756"
     CDS             complement(38010..38189)
                     /locus_tag="VQ873_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107062.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38331..38480)
                     /locus_tag="VQ873_000757"
     CDS             complement(38331..38480)
                     /locus_tag="VQ873_000757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107063.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38762..39229
                     /locus_tag="VQ873_000758"
     CDS             38762..39229
                     /locus_tag="VQ873_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3107064.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39262..39359
                     /gene="ffs"
                     /locus_tag="VQ873_000759"
     ncRNA           39262..39359
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ873_000759"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39416..39859
                     /locus_tag="VQ873_000760"
     CDS             39416..39859
                     /locus_tag="VQ873_000760"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3107065.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39861..40376
                     /locus_tag="VQ873_000761"
     CDS             39861..40376
                     /locus_tag="VQ873_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3107066.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40390..41751
                     /gene="radA"
                     /locus_tag="VQ873_000762"
     CDS             40390..41751
                     /gene="radA"
                     /locus_tag="VQ873_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3107067.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41824..42321
                     /locus_tag="VQ873_000763"
     CDS             41824..42321
                     /locus_tag="VQ873_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3107068.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42346..42540
                     /locus_tag="VQ873_000764"
     CDS             42346..42540
                     /locus_tag="VQ873_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107069.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42522..43145
                     /locus_tag="VQ873_000765"
     CDS             42522..43145
                     /locus_tag="VQ873_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3107070.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43290..44258
                     /locus_tag="VQ873_000766"
     CDS             43290..44258
                     /locus_tag="VQ873_000766"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3107071.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(44395..44507)
                     /locus_tag="VQ873_000767"
                     /pseudo
     CDS             complement(44395..44507)
                     /locus_tag="VQ873_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13875 a         7643 c        10190 g        12799 t
ORIGIN      
        1 atcggttatt attatggata atgcaagatt ccatagaatg gggaagttag aacttttatg
       61 cgaagagttt gggcataaac ttttacctct tcctccctac tcacctgagt acaatcctat
      121 tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac
      181 cttttacgag gcttttttat cctgctcttg tttcaattga ctatattaga ggcgagacat
      241 ttttcggttc tttgtcaact gtagtgggtt gaagaaagcg aagatctaga aaggacaaat
      301 ttcgtccttt cttttttgaa gttttcaaag ttcctaaaac caaaggcatt gtgcttgata
      361 agtttgatga gattattggt ggcttccagt ttggcgttgg aataaggtaa ttgaagggcg
      421 ttgacgattt tctctttatc tttgaggaag gttttaaaca gagtctgaaa aagaggtgga
      481 aaagcaagag ctgatagaga ttatagtggt gtttcaagtc ttcggaatag ctcaaaagtt
      541 tatctagaat ttctttatta gtcaagtgca tacgaaaagt agggcgataa aatcgtttat
      601 cactcagttt ctgactatct tgttgaatga gctttcagta tcgcttgata gccttgtatt
      661 catgggattt cggatgatgg cttgtgttct gctctcaaga acagttatga tattgagctt
      721 atcaaagtct tgagcaataa agctcatttc catctcccga ttgaaacagt cactccccgg
      781 actgtttcaa cgtcctagga cataatctca ggaagacgcg aaaaatcatg ctcaaagtga
      841 aaatcattgt tcttgcgaat gacagttgaa gttgaaatag acaactgatg atcaatgtcg
      901 gtcatagaag tctttttaat tagcttctga gcaatctttt ggttgatgat acaaggaatt
      961 tgatgattct tcttgacgat agaagtttca gcgaccatca tttttgaaca gtgatagcac
     1021 ttaaaacggc cttttctaag aagaattcta gtttgaattt tttatactag aaaatcagaa
     1081 ccataatacc tatataaaaa tattatagtt ctaataggat ttacccaaaa gttttaaggc
     1141 ggtcttttta gaactttaat cgtttgaaat ttaggtagca aatttgtttc tattttgtca
     1201 acttttccta tttttatctt gttgaggctg gtattttaac aattcaggaa ttgatagtga
     1261 atgtgtaaaa ttttttgtta gaataagttt ataaaaaaga aaaggagtat ttgattatgt
     1321 tacaaaaaat ttatgagcag atggctaatt tctatgatag tattgaagaa gagtatggtc
     1381 ctacatttgg tgataatttt gactgggaac atgttcattt taaattttta atttattatt
     1441 tagtgagata tggcattggt tgtcgtaggg attttatcgt ttaccattat cgtgttgctt
     1501 atcgtttgta tcttgaaaaa ttggtaatga atcggggttt tatttcttgt tgaggtaatt
     1561 ttagtaaatt tccgaactaa tttactcttt tatggaaaga taatagtaaa tagctagtaa
     1621 tttttctaaa tcatttttta atagttggaa atagcaaatc tttctattgt ttcttcttga
     1681 taaaaaggcg attttttatt ataataaatt gtaagatata attgcaggtg agagtcctgc
     1741 catgtatgtg agaaaggaag agcctgaggg ctcagacaaa attatgactt cagttgttgt
     1801 tgtaggtacc caatggggtg atgaaggtaa agggaagatt acagacttcc tttcagcgaa
     1861 tgcagaagtg attgcacgtt accaaggtgg tgataatgct ggtcacacga ttgtgattga
     1921 cggtaagaaa tttaagttgc acttgattcc atctgggatt ttcttccctg aaaaaatatc
     1981 tgtcattggg aatggtatgg ttgtaaatcc taaatctctt gtaaaagagt tgagctatct
     2041 tcatgaggaa ggtgtaacaa ctgataactt acgtatttct gatcgtgcgc atgttatttt
     2101 gccttatcat atcgagttgg atcgcttgca agaagaagct aagggcgaca ataagattgg
     2161 tacgacaatt aagggaattg gtccagctta tatggacaag gctgctcgtg ttggaattcg
     2221 tattgcagat cttttagata aagatatttt ccgtgagcgt ttagaacgta accttgctga
     2281 aaagaatcgt ctttttgaaa aattgtatga cagtaaagcg attgttttcg atgatatttt
     2341 tgaagaatat tacgaatatg gtcaacaaat caagaaatac gtgatagata catctgttat
     2401 cttgaatgat gcgcttgata atggcaaacg tgtgcttttt gaaggtgcac aaggtgttat
     2461 gctagatatc gaccaaggta cttatccatt tgttacgtca tcaaaccctg tagctggtgg
     2521 tgtgacaatt ggttctggtg tcggtccaag caagattgac aaggttgtag gtgtatgtaa
     2581 agcttatacg agtcgtgtag gagatggtcc tttcccaact gagttgtttg atgaagtggg
     2641 agaacgtatc cgtgaagtgg gtcatgaata tggtacaaca actggtcgtc cacgtcgtgt
     2701 aggttggttt gactcagttg tgatgcgtca tagccgtcgt gtttctggta ttactaacct
     2761 ttctttgaac tctattgatg ttttgagcgg tttggatact gtgaaaatct gtgtggccta
     2821 tgatcttgac ggtcaacgta ttgactacta tccagctagt cttgagcaat tgaaacgttg
     2881 caagcctatc tatgaagagt tgccaggttg gtcagaagat attaccggag ttcgcaattt
     2941 ggaagatctt cctgagaatg cgcgtaacta tgttcgtcgt gtgagtgaat tggttggcgt
     3001 tcgtatttct actttctcag taggtcctgg tcgtgaacaa acaaatattt tagaaagtgt
     3061 ttggtcctaa gagattttta agatttgttt aagataggtc gggtatacta tagacagtta
     3121 taagaagacc tcctaacttg ttgtaacaaa tatcctaaac ttttcttttt cataataatc
     3181 tcccttaact ccacccaatc aggtggagtt ttttagctct atttcaggct tttggggact
     3241 attctaaaaa taatttttcg atatttttcg gattttggtc ggggaattgg cggggacttt
     3301 tttagcgaat atgactaaga aataggtctg ttgtcgcttc agcaagttcg tcctctactt
     3361 gattgtaacg atccgtcata taaacctttg tatgccccag cgcctggctt aattgttcaa
     3421 gcggaacccc tgcaataatg ctttgagtcg tgaagaagtg gcgcatcatg tgaggtgtta
     3481 catgcaatcc tgttgcttca ttcactagat tgaagtttct atttagctga tttggattga
     3541 tgagaccacc tttctcgttg atagttatat aatccttgtg ctgttccttg ataattccta
     3601 actttcgctt aatcttagaa gcttcagcta tcagataata gatcaggtct gttccgatat
     3661 catcaaggca gacatatcgc tctgaatcct tcgttttaag ccctcctttc ccttttaagg
     3721 tctggttgct tcgactgtct ctaagatgca gtatagcccg tccgctgtcg ttctgagtga
     3781 tgtccattgg acgcaatcca aagacttctc ctcttctcaa tccaaaaatt gtcagatagg
     3841 tcagagcgta gaattgtttt ggcataatct cttctgcctt tgctatccaa gtcttgaact
     3901 ctttgagagt cactttcttg tttgcagcag ggatatcact ctggccgatg aaaacacctt
     3961 tcaagcgatt tgagagcaga tttccatttt tgacggcatc attcagcaat gccatgaagc
     4021 tggaattgag ggtttgaaca gtgtatctgg tatggttctg caacttttca gcgataaata
     4081 gttcatactc atttctatcc aaatttttaa gcaggataga accaaacttt gccttgatat
     4141 ggttcttata gagattgtca ttgaggtagt aggaagtgtc attccagcgc cctgttgaca
     4201 atctcttttc agaatagata tcccaatatt gatcaagcgt tagattcgta ttgataccta
     4261 attcttgttc ttggatttgt tgctcaagct ctaccaaggc tgcacgagct tgagggagag
     4321 ttgtgaaacc acttttactt ttttctcttt ttttacctcg gaagaaaaaa gaacgtctga
     4381 catagtaacg cttgccttta gcagtctcat agtaatagat atttgggtat tttgttttat
     4441 tatatttcat tgtattctcc ttgtttatcg gcttctggac aaggtctaaa cattgagaat
     4501 attgacatca cccctttcat ggtgtaaaat agggtataga aaagaggcct ttttaatggc
     4561 tgatttttta taagggtaag cttcacaatc aaactttggc gagggcgatt gtggggcttt
     4621 ttttttattt tctgaatagt ttgtatagtt tatacaaact ccaagctgtc aaagggactg
     4681 caaggaatgg agcgattgga ataccaacaa ctccaaaaaa gactaagaaa agatacagtg
     4741 ctgaaaatat gattttattg gcaggaagtt ttttcttagg agatgtttct gaaagattaa
     4801 tctcgtttac tatatcagcg acactgtcac taacaatatt ttgttcaata tgttcagttt
     4861 cagttgtttt agtttcaata gcttcagttt ccgtaacttc tttattggaa atgttatcat
     4921 caattatctc agatgattcg ctctgaatta cttctttttg tgaagaatca acaatggtaa
     4981 ggtaaatttc aaaaccaaca tccaaatcat tatttgtgac aactttttct tcatactcgt
     5041 cccattcttt atatgggcca ccttttatct ctccctctat tacaaagtta tattttttat
     5101 tatcaaaata ttttcgtatt gttttagcaa tggttgcagg aacatatcct acatgattat
     5161 caaatatcaa aacttttata gcattaggat catatctatt atctacttct ggaacgagct
     5221 caatattgaa aaagtctaaa tcttgatatt tgaaaacttt cagaccatat tcttcaagtt
     5281 cttctctaag ttccttagtt gataaattgc tatagtactt tgcatattct gggattccgt
     5341 tatcttcagc aatcatattg caagcttctt ttactgcttt tttatatttt gtcactccag
     5401 cgactctgaa taatattttt tcaacagtct tttgcatata tttcccctct atataaatat
     5461 cttcaatgca atttttaatt tactaatgcc aagtactctt ccttgaccat gacttcatta
     5521 gtcatagttt ttagattgta gtaagacatg aatttgaggt aatcaaactc tgtggggtcg
     5581 tctaagcttt ctagtgcgtc tttcacgaga tgatggatca tattcctatc agcttcgttt
     5641 tcacagcgta ggcgagcgtt ttggtactct gagcgtgtat ggtctttgtg tccgagttag
     5701 tgtagggcga cttggatttg ttgttcagga gctaagttgt ggtcaatagc gagtacgttt
     5761 gtgtctggat tgtagaaacc gctactgtgc cagtttgaac cgtcgaagag acaaagctct
     5821 acttgatatt cttcgcagag tttagcgagt atcatagttc tccttcgtta tttataaaca
     5881 tctctgcggt gggcgatttc cacggctagg acgactagtt tatcgtcttg gatatcacag
     5941 atgatgcggt aattctctac tctgtatcgc cagtaacctg caaggttggc ttttagtgct
     6001 tttccgtgtt gtcgtggatt ggtcgtgttt tcaatgtttt tagcaagcca ggataggatt
     6061 tgttttctgg ttggggtatc tagtttttta agttgcttga gagctttttt atcaatatct
     6121 agccgataca ttaagcaata tcctctcgag atagtcctag ttcatccaag acctcatcca
     6181 tggtataagt agctgggtcg gctaaatact ccatataggc ttggtcggct gctcgtgcgt
     6241 cttcgatatc ttccatgagt accatgaagt cgtcaaaatc catggttgtt gtgtcgatac
     6301 cgtgtttggt taggtagtcc gtgatgtagg agtttttttc tgtgaaattg atcgtgatag
     6361 tcattagcgt tctcctttgc ttttgaagtg ggcggataga acggatgtga tgaagtcgat
     6421 atcatcttca tttagtggtt ttccgtcaaa taacatggtg ttggctgctg ctttgcgtaa
     6481 gtctatgatt tgtccattta cttgagcaaa ttcatcactt ccagcgatag caggattatc
     6541 tgtccgtccg agtaggtagt cagcacttac attaaaataa tcagctattt cttttaaaac
     6601 ttttgaacta ggattacttc tttttaatcg atataaagta ttagttccat aaccaagttt
     6661 ttcttctaaa atatttatag aaatcccctg tttatcagct aattctttta ttttatcgaa
     6721 tgctacaaac attaattttt caacctttct aagcaaacga aaaataattt taaaatattt
     6781 gtagaaaata gttgacttat ttagtcaaat gttttaaaat aatattcgta agctaaagag
     6841 ttagcgaact agacaactaa aaaataaagc cttacaaaac tgattggcgt ccgtttactg
     6901 taggtaaaac ttacttttag taggtctttt ctctatgttt ttattttaaa acatttgact
     6961 agagttgtca agaagttcgc taacttttta gataattttt taaaaggagg tcagggatga
     7021 acgaagaaga cctgaaagaa ttattggaac tcttagcgac agattatggg cgagggtatc
     7081 tagatggagt agttggggga ctttcaatgc ttttgaaaat ttcaaaagaa gcagagaaat
     7141 atagaaagga aaaatatgag taaagcaaaa ttattagtca cataaagtag gtaaacgagg
     7201 taggaaatga tagaaacact ggaaataaaa ataaacaaaa agacatactt catatctgca
     7261 agggcagatg ttccagtcag gtataaagtt atgtttggca gaaatctctt cgatgacttt
     7321 tcgaaaataa aaaacaataa agatgaaact ctatcacttt gtctattatt ttgtatgaca
     7381 gacaaatcgt cagaagaatt ctgtaaattt tttattgaaa ataattcata tataacaagt
     7441 agacatcact atgaggcaat aagattattt gaaaaacatt ttatctttaa gcccgtaaca
     7501 tattcactag aggacatagt tcaaatccta acaatatatc tagaaaatac taaaacacag
     7561 attggaggaa aaaatgagta aagaactaaa aataattaag gctaaaatta aaactcgttt
     7621 gattgagttg gatatgactc aagtcgaatt ggcaaaacaa gtatctgtag catcatcagt
     7681 tatttcagag ttgctgaagt atggaaaagg aagtgattat gtgaaagaaa aagtcgtaga
     7741 tattttgggt attgaaaacc cttgggaaaa tagttagagc atgaggaaat agtatgaaca
     7801 acgcagcgca aaaagtaaca cggattgaca aagatgcctg ggagattgct acggagctgg
     7861 cgaacgagta cggcgtatct atttgtcaca tcatcagcga gagcgtccgc tactgtgcag
     7921 agaatgccga atttaaggag atggacgttg tcgttaaacg attggtagtc ggcagtaagg
     7981 tgctggagta ggagggtgga gatgaatgaa ctagtatggt tttactttgt tgtcataatc
     8041 aatcttatca ttggttttgc tacatactac gctagcaaaa gagatagaga aaagcgcatc
     8101 aacgggttta aaaaaataca agatgatgag cttgaaagag ttagaaataa atttaattta
     8161 tgatttttta gaagtctttt gaataaatct tttatttaag ttttgtttgc tattgcttgc
     8221 tttattagct atttttaaag ctttgtcaaa atcaacctcg cctgtaaaaa ctttgtaggt
     8281 aagatcattc atcttcatag acttgtcggt ttcagtatca agctgagata ccttctcaag
     8341 ttcttgcaac cgtaattcat gagcttgttt gattttttca agttcaaagg catgttgctg
     8401 ttttagagta tctatctgat gatgaaattc tctttcgagt ttttcaacag tatgtgaatg
     8461 ttctttggct tgtttttcaa tctcagcttt attgttagct tttgatgcga catatgacca
     8521 taaccctgat attattgcaa gaataatact aatcacaggt tgaataagag cttgatattc
     8581 cataagattt ctccaatcgt tttattttaa ttataccaaa tttagaaagg aactttatga
     8641 acgaaatttt taattttcac gggcaggaag tccgtacttt gatcattgat gacgaacctt
     8701 ggttcgttgg gaaagatgtt gcagacatcc taggatatag caaggctaga aatgcgattg
     8761 ctcttcatgt tgatgaagat gacgccctaa aacagggcct cacagataat ttaggaaggg
     8821 ttcaagaaac tatcatcatc aacgaatctg gcctctactc tcttatctta tccagcaagt
     8881 tgcctcaggc taaagagttt aagcgctggg tgacatcaga ggttttgcca gctattcgca
     8941 agcagggcgg tttcattcgc gaggacttgg acgaggatgc ctttatcgct ctgtttactg
     9001 gccagaagaa attacgtgag caacaggcga ccatgctgga agatattgac tatctcaaga
     9061 gtgagcaacc gattcaccca agctatgcta aatcgctcct gaagaagcgt aaggctcggg
     9121 tcgtggtttg cttaggtggc attgatagtc cggcttatgc ggataagact ttcgctcagt
     9181 cagtctttag acaagctgag attgacttta aagaccactt caacattaat cgctatgact
     9241 tgctaccgaa aaaattcgca gatgcagcct tggcctattg gatgacttgg gagccaagca
     9301 ccaataccaa gatgaaaatc atgaaattga actcatttga cgaagggtag gaggggaaga
     9361 agatggacaa tgttctactt tcactgtctg aatggattaa atccattatc aaggacacaa
     9421 tcacaaggct agtcgaaata gaaaaagata gtgaccacta tccagagctg atggatgtga
     9481 acactacctg tgattttcta ggaattaagt atgccacctt ttcagataat tatcgttact
     9541 taaagggatt tccaaaggaa ttacctggta agaaatggtc aaaaagagcc atcaaagaat
     9601 ggctctctaa tcaaatataa taactttact aaaaggcttc tggacaaggt cttagcaaaa
     9661 ttatttgact atattatagc acaaaaagag gataaggaga taaaaatgtt tgaaccaccg
     9721 attttagacc agctgatggg ggttggagcc ttactgcttg gatttgcagg ggcttgccgt
     9781 catatcaaat tgcaggaaca acgcaaggaa gaagaaagac gagaagagca agaatttgcg
     9841 tctatgatta tccaagtgcg taatcatgca tatgaacgtg gtagagagga caaatggcaa
     9901 gaaattcgca agaatattcg cagagagttc aaaggattca catatgacaa cgaaccgcct
     9961 gtaggcttgc gtcctgagcc gttagctttg ccagaaccta aacagtctgc aatcagattt
    10021 ttgtaatgag gaggtcagga aatgcaagaa ttgattgaat cgctggataa cctgattatg
    10081 attgttaaag aactggaagg aagggaatca acttcaagac attttattac gatatgggaa
    10141 aacgattata aaaatctatt acgagtcaaa gaatacctaa ccgactatga aaaactagca
    10201 aaggactatc gttatatgac ccttaaaaat aagctgctaa agattgaaaa aatggagctg
    10261 gaaggcaggt acatctatga agatatgcgg atgaagtatc gtgccaatcg caggaagtgg
    10321 ggtgctcggt atgtctgaaa tcaagtggat aaaaatcaaa acggatattt ttgacgatga
    10381 aaagatgtgt ctaattgatg cctcgcctga tcgtgatgca attattgtaa tctggatcaa
    10441 acttataaca ctagcaggca aattgaatac aaaaggcgta ctaaccattt ctaaaaacat
    10501 tgtatacacc gatgaaatgc ttgcacaaac gttccaccgt ccgttgaata cagttcgtat
    10561 ggctcttgaa gtttttgaaa agtttggaat ggttgaaaaa atcgatggag tgataatgtt
    10621 acccaattgg gagaaacatc agaacattga cggcatggaa aaaataaaag agcaaaatcg
    10681 aaatagagca gcacgtcacc gacaaaaaca gaaattactt gcacagaaca acgaaagtaa
    10741 cgttactgat aacgttatgg ataacgttac agtaacgcat ggtaacgcac tagataaaga
    10801 attagataaa gatatagaga taaataataa taaggtgatg attagttcca gcctttctga
    10861 aaatttgaaa aatagcggaa tccatctaac tgataagtca catcaacagt tacttgatta
    10921 tgtgggactt gatggaatga gtttcgatat gttgaaccgt gcagtcgaga aaacttccgg
    10981 atcacacaaa cctagtttca attacctaat agccattctt gaaagttgga aaaagaaagg
    11041 cttcacatcg attgagcagg tggatgagga cgaccgtaaa tataaagagg gtaagaagtc
    11101 aagacaacaa aacgataaaa catcggaaca ggaggtaagg gacgaatggg gattttagaa
    11161 ctaattgagc agttcgagat tgactattat ccgttaagct acgagaagaa aactctttta
    11221 gcagaccaac caattcatcc agtggttgcc tgcttgtctg aaatggctag ctggcatgaa
    11281 tgcggaggtc ggctagtatg gtagacaatg tgtttgagga aatcgcctta tcttatcgta
    11341 ggaatacaga acaacaagaa gagttctgcg aaaagcataa catccctttg ataaagatat
    11401 tgaggaccga gagtgttgta tgtcgcatgt gtgaatctga gcggattcat gaagaaaatc
    11461 aggaaagagt gaatgaactg gctaatgctg agaatgagcg agagaggaaa tactatcttg
    11521 aaaagttctc tctttatgat gaaattttga aaaatgctac tttggacaat tttgaaacac
    11581 caaccgaaaa agaagcggaa aagctagctt ttgcaaagag gatttgtcgt gagtggtctg
    11641 agggtgctag gaacaacatt gtacttcagg gagaagctgg aactggtaag agtcatttgg
    11701 cttttgctat ggttaaggct ctatctgagt acacgaaaga gattgctatt tttattaacg
    11761 taactgactt gctgatgaag attaaagctg attttagtca ggaagagttt ctggtcaata
    11821 aaattgctag tgctaagttc ttggttttgg atgatttagg aatggaaaaa gatagcgaat
    11881 ggtcatttac tattctctac aatatcttga ataagcgttc aaacacaatc attaccacaa
    11941 atttgatttc tgccgatatt caaaaaagat atggcagacc tttcatgtcc agactaatga
    12001 agggtgtaga taaagaccat ttgatggttt tcaatgattt gacaaacaag cgaaagcaat
    12061 atttttagaa taggggtggc tgatgtttat tttaaagcat gggacaagag aggataagcc
    12121 gtttctaagg tctgcaatta tcagtgtgac tggcttggat atttcgtgtt ctgaggagaa
    12181 gaaagccatg cggtttattt ctcgggcggc agccttacag gttagcaagg cattgagagg
    12241 ttcctttggg aacttctacc ctgtcgaggt ggagtgatgt tagagcttta tttcgtctac
    12301 aacgggcact gtaagttttt ccttgggagg tttgacaatg tcgatgatct cattgagcag
    12361 atggaagacc atcagtgggc tttctcagct atcactcatc caaggtttca gaagcacatt
    12421 ggtcagcgga cgacacgatt tgactacggt tctaaggatt gttactattt agcgactttt
    12481 tcaggaggag aaaaaaatga ttgaacttat taaagaattt ggaatggcta ttctgtggtt
    12541 atttcttggc tatttagtcg gggaacgtgc agcaagaaag gaaaagaaag atgatcaata
    12601 acgttacatt tttagtggga ggtaagaaac atggttggag taacctatca ggaaattcat
    12661 ctctttgttg aatttttgaa agagcagtac gggcaaggtc gtccagacta tattgaagcc
    12721 ctgaacgact tagacggtct ggtggaagtc tcctacagag aagctattga aagattttta
    12781 gaagatgaag tacgataaac aggctgagat tgacggactg aaacgcacga tcgagcaaaa
    12841 cgaagagaag ataatcgagt attcgaagcc gtgcgatgca cgcaagagac ggattagagc
    12901 gctggagcgc gatttgttga ggaaaaagaa taaagaatta agacggaaag cggaggagtt
    12961 ggaatatgat ggaagagtta aagcaaaaag ttaatgaagt atacaactgg acggtagaag
    13021 acgggaagcc gcaacctccc aagcaagatt taccacaagc ggtgaaagac cgggcggact
    13081 atttttggga aatggcagaa gatggtatga cgtttatggg agcgatggaa tgcatcttcg
    13141 ctgatgaaaa gcctacagac tatgatttgg gagctactaa gggttggttg ccaaaatcta
    13201 aggagtttga tgattgggtt ggctattcgc caagcatgtc tcagttagtt attgcagttt
    13261 atttgattta cagaggaagc gaagatgaaa cttaatgaat tgattaagaa atataaaaaa
    13321 cttgagggtg tatggaatgc tgaaggagca gaactagttc gtcaaatttt tctgcaagac
    13381 ttggaacaac tagataaacc gcaaccagtc aaagttccgc agtgtgtggc ggaatatata
    13441 gaatttaaaa agaaaaacaa ttttcatgtt tacggtcttg cttggcttaa cggctacgag
    13501 gtcgaaaaag agaagcggta ttttgttaag attaaaggga atattaaaga aaatatgttg
    13561 gtttatggag aacttttgaa aaggtatttc tttacaaaaa gctttagttt agacgatgtt
    13621 atatattccc acactcgtaa agaactagaa gccgcaaact tcggctgggt gtttgattgc
    13681 ccaggtattg agattgagga ggtggaataa tgggagatat acgaatacta gacgcttgtt
    13741 gtggcagtcg tatgttttgg tttgataaaa atgagagtca tacaactttc atggacatca
    13801 gacaagaaaa atttgaaata catggaaaaa ggtaaacgta aaccctgacg ttgtcggaga
    13861 ttttcgtgat atgccattcg atggtgaaac atttaatcta gtagtatttg atccgccaca
    13921 tttgaaatgg gcaggtcaaa actcaattat gcgatcacaa tatggccagc tggataaagt
    13981 tacctggtcg gaagatttag ccaagggttt tgaagaatgt atgagagttc taaaagttgg
    14041 aggtactcta gtttttaaat ggtctgattg tcaaatcaac gttaaagaag ttcttaaatc
    14101 tgtacctttt aaaccattgt ttggacaaca aagaggtact acgcattgga tgacgtttat
    14161 gaaatttgag aaggtcacag agagaaagga cggcacgttt gtaaaagagg aggatttggc
    14221 atgataccga aatttagagt gtggcatcat gaattaggta gactgatgtc agtcaaatgt
    14281 atgttttttc aggatagcga gattgaagaa tttgagttaa acgatgcttt aatgaatgat
    14341 tacattacag cttatcctga tgaaatcgaa ctcatgcaat caacaggact caaagacaag
    14401 aacggcaagg aggtattcat cggtgacatc gttaaatgta caagaggatg tctccatgaa
    14461 gtatatttag aaaaagaata cggtggtaca ttcataggtg gaatgcctgc tgtataccta
    14521 aaaggacttg gagatggata tgcgtggacg gaatatgagg aaatcatcgg caacatctac
    14581 gaaaatccag agcttttgga ggataaataa tgaacccaga aataattgac aatataaaca
    14641 aaccaagcca ctaccaaggt gcaaacggtc ttgaggctat cgatgttgtg cataacttcg
    14701 ttgggagcct ttccggagcg tctgctttct tttggggcaa cgcaatcaag tatatgttac
    14761 ggtttcaaaa gaaaaatggt ctggaagacc tgaagaaagc tagaaagaaa cttgactggc
    14821 tgattgagga gatggagcat gagtgaatac gcattgtatg aaggcgacac ctttattacc
    14881 atggggacgc ttgcggaaat cagcaaagaa acaggaattg ctgaacggtg caagtatttc
    14941 agagtttgcc atcgaagata tctgtacgtt ttttgggatt gagatccaag aaaggaaata
    15001 aaagtcaatg aacaaaagaa ttaagaagaa gatagctaaa cggcagatac aagaaaagca
    15061 agaagaatta tacaaacaac tacggaaatt aagttctgaa gaaattgaag ctataactaa
    15121 aatgattaat caggcagttt ctaatattcg caaggctttc tctcagatat ttgataactt
    15181 gtttacattt ttgaaaaact tggaggtgga aattgaaaaa attgagcgac gaagaactca
    15241 aaacgttaga cagagaactt ttcaaatttc aaaacattca acgcacaata gacttaagaa
    15301 ggctagaatt agaaaccaga aacccagatg ctcaaagtgg gccaactgta ggaataagca
    15361 aacctaccga aactatcgca atcagaatcg cagatgatcc gactttaaaa tttcttgaag
    15421 gatttaaagg gattattaac aaactcttaa gcaatctagt cgaggaggac aaagaaattt
    15481 tcaatctacg ctggagatac cctcaactga gatgggaaga aatagcagaa cagaaattca
    15541 tgagcaaagc tacaatctat cgacgtagaa ggattatctt agaacagtac gctataatga
    15601 aaggtgagtt gtaaataaga ttgagacaaa agacatcttg aagtctcaca aaaaaagggc
    15661 tattatgata gcatgaactt ctgaaaacaa aaacacaaat cacatgttgg agttatccta
    15721 tttttacaga aaagttgttt aacagaggaa catcatgagt cagcaaccag ctggcttttt
    15781 gttttgtaga aaggaggcag ttatggaatt tgtatcaccg ataaaagaca atgataatat
    15841 tcaagctatg aaagattatc tcagagaatg gaatgagatg tattatatgc tattcatcac
    15901 aggcctgaat actggcttac gagtcggaga tatacttacc ttgaaagtta aagatgttca
    15961 aggttggcac atcaaactga gagaacggaa gactggcaag cagataacaa gacggatgac
    16021 aaaagaactc aagaaagaaa tgaggagata tgttgaaggc aaaccatttc atcatttctt
    16081 attcaagagt aggcaaggtc agaataaagc gatcactcgt gagcgagcct atcaaatcat
    16141 acatgaagca gctgaagaac ttggcattga taatgttggc acacatacaa tgcgcaagac
    16201 attcggctat aaatattaca acaagacaaa ggacgtagga acattacaga aaatgttcaa
    16261 tcactcatca cctgcaatca ccctgagata catagggata gagcaagcag agcttgatga
    16321 cgcactacgg aactttgtca tttaattttt tagatattac tttcacataa tgagttaagc
    16381 ataaactgaa aaaatgaaag tcttcaaaac ctatgattag taagggtttg agatttagag
    16441 tgagtttaac aaaatataag atatgtgaaa gtgagggata aaattggtat agttacaaga
    16501 ggtgaaaaat ggtaaaagaa taccgtgatg attttcttgg agaaaaggcc ttcgagaaat
    16561 taaataaaga tattgatgcc aatcctgaag ttggctttga aattgttgga tatactcaaa
    16621 cagcatttgt aaatggaatg catataccgt taacagccat actagtaaaa tggaataatt
    16681 tttttaaaga atcagaatga gacaaaagac atcttgaagt ctcacaaaaa aaggtttatt
    16741 atggtagcat agatttcttg tatgaggagg ggataggtca aaggcctatc ccttttagca
    16801 ttgagaaagg aggtttgaga tgtataacaa acctatcaga ccatccttga aatctaagaa
    16861 gtgggagaag ttccgtgata ggataatgcg taagcatgat tatctttgcc aagaaagttt
    16921 gcgttacgga atttctgttc aagcagaaat ggtacatcat atctttcctg tgtctgaata
    16981 tcctgagctt gaatttgttg aatggaattg cttgccattg acgaataaga aacataatac
    17041 gtttcatgat agagtgaacg atagagtaat caaccaagga ttgtattggc agaaaaaaag
    17101 aaaaaaagaa tttttaaatt ttttcaaaaa tgaaaaatga aaatttttaa tccccccctc
    17161 tttttgaaaa atcattttgg ccagtagggt actggtgaag ggaacttttt ccaagtcggg
    17221 ggccttcaaa caaaaagggg gtaaaaacta agcgattttg acgaaaggag gtagtttttg
    17281 gctaaaccaa ttacagcaaa gtcgattaag tcaaaagtgg tcaagcagat gaaagacttg
    17341 ggaacttatc gtaaagagtt cgaaatgatc attgacattt ttgcaggtat gttataccag
    17401 tatcagaaac ttgctcaaga ttatgctgat atgggttatc cagtaacaga cacctacgtc
    17461 aataaggctg gtgctgaaaa tgagcgcaaa gttccaatct tgacagcgat ggaaattttg
    17521 aggaaagata tactcagcta ctctaatcag ttgatgatga atcctaagtc gctcggtgag
    17581 gtagtagaac aagagggtga gtcagttctt actgaggtac tgaagttcaa gaacgaaatc
    17641 aagaagaagc gagtgactgg caatgggtaa tcttgataaa gctaaaaaat acgctcaaca
    17701 cgtcttaact caccgagaag aacattgcga agaaaacatc cttgctgctg aacgtttttt
    17761 ccgtgattta gaaaatccaa cctttgagat ggatgaggat atggtggatt ttgttattca
    17821 ctttatcgag aacgtgatag ttcatcagca gggcgatgat atgtttgcgg tatctatccg
    17881 taacaagcca ttgcttttgc aaccgtggca acatttcgtt gtagttaatc tgtttggttt
    17941 ttactacaag ggtacgaatg agcgcaggtt caaagaagcg cttatcatgc ttgctcggaa
    18001 gaatgggaag acctcgttta ctgctgcaat cgcacttgct tatcagatat tagatacaga
    18061 tagcggttcc aaatgctata tcgttgctaa ctcagtcaag caagcgatgg aagcttttgg
    18121 ttttttaaga ttcaacgttg aacgctggaa cgataagaac attcgtatca aggataataa
    18181 ccaagaacac tctatcaccg ccaattttgg tgatgaaggt tctttcttta tccaggcttt
    18241 agcgaatgat gagagccgtc tggactcttt gaacggaaat gttatcatct tggacgaagc
    18301 tcacacaatg aggaacagta agaaacatgg tcttatgaaa aaaacaatgt cagcatacag
    18361 aaacagtatg ctttttgtta tctcaacggc tggggatatt cctaccgggt tccttgctaa
    18421 ccgtctgaaa tactgtcaaa aggtgctcaa gcaattagtc actgatgatt catttttcat
    18481 cttcatctgc aaggctaatc aatctgctga tggggacgtg gtgaactatc tggacgagaa
    18541 tatcctcaag atggctaatc cgtcatgggg tgtcacggtt tcgctcaagg ctctcaagga
    18601 agaagcagag caggctatga atgatcctca gacaagaaat gagtttttca ataagacctt
    18661 gaatatcttc actaactcta tgaacgctta ttttaatcct gatgagttta ttgcgtcgga
    18721 tagttgctac gattggagtt tagaagagct ggcacgtttg cctattcgtt ggtatggtgg
    18781 tgcggacttg tcaagattgc acgacttaac agctgctgct ctctatggtg tctatcatga
    18841 cggtgagaaa gacgttgata tctgtatcac acatgctttc ttccctcgga ttaatgctca
    18901 gaaaaaagct aatgatgacg ggattccact ctttgggtgg cagtctgacg gttggttgac
    18961 gatgagcaac actccgaccg tcctctatga tgatatcgtc aaatggttca tcaagatgag
    19021 ggagaaaggg ttcaagattg ctgctgtcgg aatggatagg aagtttggcc gtgagttctt
    19081 gacgaagatg aaacaagctc ggttcaagat gattgaccaa cctcagcttt tttatctgaa
    19141 atcagaggga ttcagacgga ttgagtttaa agttaagaat aaagaatttt actatcttca
    19201 ttctgatgct tacgaatact gtgtgagcaa tgttagagca attgaaaagg tggacgatgc
    19261 tgtgcaatat gagaaattag atggagacgg tgggactgca aggattgact tgtttgatgc
    19321 cagcgtcttt gcttgtatac aggctcttgc taatcttggc aagggtggtg atgtgatgag
    19381 attctttgat taggtgaatt atgaatgaaa tagtattatc agaacatgaa attaacttgc
    19441 tgatcaacaa agggcgagtt aaagtaattt taaacgggga agtagtaact attcgtcaaa
    19501 gacatatgaa aaatttgatg gctgaaacag taaaatggga aaaacaggta attgatgtca
    19561 gtcagaatat cgtaagaaat aaacactttg attcactttt tcaaaatact tttcgttaga
    19621 aaggaggtga ggaaacatgg gtatttttga aaagttttgg aaacgaaaca agccaagtaa
    19681 gtcaatcaac atgctgagtc attcagattt agggttgtca aacctgatgg actcgtatgt
    19741 acctttggcc agaaatccag atgtggtgac agcggttaat aagattgctg atttggtctc
    19801 taatatgacc atccacttga tggagaatac agataaaggt gatatcagaa tccgtgatgg
    19861 gcttgctaga aagattgata tcaatccgtg taaacacatg acaaggaagt catggatttt
    19921 caagattgtg cgcgatttgc ttttatatgg cgatgggaac tctgtcctac atgtggaata
    19981 tgaacctgtt acggattata tttctaatct aagaccattt ccgatgagag aggtttcatt
    20041 ccaaacagat aaggattcct atgtaatctc atttaggggt gaagaatatt cccctgatga
    20101 agtagtccac ttcgtcatca atccagatcc agatattcca tacattggta ctggttttag
    20161 ggtgacgttg acagatgtgg ttcaaagttt gaacatggct accaagacta aaaaaagctt
    20221 tatgaacggg aagaatattc ctagtcttat cgttaaagta gactcgtcta gtgctgaact
    20281 agattcggag caagggcgtg agcgtatcgc tgagaagtat ttgagtacta gcagggttgg
    20341 cgctccatgg attgttccag aggcattgct ggacattcag caggtaaaac cgcttagtct
    20401 aacggacatc gctttaaacg agtctgtgga attggataaa agaacagttg caggtctatt
    20461 aggagtacct gcttttattt tgggtgtagg agagttcaac aagacagagt ataacaactt
    20521 tgtaaatacg actgtcatga gtattgctac cactattact caaacactaa ccagggactt
    20581 acttttgtct agcaatcgtt acttcaagct aaatcctcgt tcactcttct cttacaacat
    20641 tacggagttg tctgctgttg ctcaacaaat ggcaaacagt gctgcaatgc gtcgtaatga
    20701 gtggagggat tggctaggga tggctcctga tcctgagatg gaagagttga ttgttcttga
    20761 aaactttctc cctcaggaga aactaggaga tcaaaataaa ctgaagggag gtgaggaaga
    20821 gaatgcaaaa gcgaaatagc tatcgtgcca ctcaatttca aacgagagaa gaagaatctg
    20881 gtgatttgat tttgagtggc tactttatca agtttgacga ggagacggaa ttgtggccag
    20941 gctactgtga agttatcaag cgtgctggtg ttgagaaagc tgtcacagac gctgatatca
    21001 gagctttatt taaccatgat gatagccttg ttctcggtcg aacaggtaac ggaactctga
    21061 cactgggtgt tgatgatgtt ggtctttttg gagatatcat cattaacaag gatgatcctc
    21121 aagctgttgg ggcctatgcc cgtgtcaagc gtggagatgt tatagggtgt agctttggct
    21181 ttatcccggt aaaaatcgaa acggaagaac gtgaagatgg ttcatatttg gacactgtct
    21241 tagagctaga aatctttgaa gtgagtccat gtactttccc agcctatcca caaacggaaa
    21301 ttgctgcacg acaaaaagac ttcgaaagtc agaagcgtgc taatcgtgaa gcgctagaca
    21361 agcgcaagaa agaaattaag gagaaattta atctatgaac aaattattga ttttgggcgc
    21421 tcgtatgcgc aacaaagcag acaaagttgt agagcttgaa gaatcaatca aagaattgaa
    21481 caagcgttct gaacttgaag ctaagaaatt ggaacaagct ggaactgacg aagaagtttc
    21541 agcagttgaa aagaaccttg aagacatcca aaaagaatcg gatgaaaagg aagcagaaaa
    21601 agaacaactt gaaaaagaaa tcgaagattt gaaaaatcaa gttgaagaac taaatcgtaa
    21661 agcaccgact tacccaagtc aagaaaaacg tggaggacag aaattggaac gacgtgacgc
    21721 aatcgctaaa tacattcgta ctggtcaaac tcgtgacatt gtaggcttga aaactactga
    21781 ttcaggaagc gcagctttaa tccctactga agttttgaaa cctcattttg ttaataaaac
    21841 acgtaatcca cttttggatc ttgtggaacg tgtgaaagtt aatagtggat ctggtaaata
    21901 tccagttatc aagaaaacgg atggtgtaat ggtttcaata gatgaattga aatcaaatcc
    21961 agaactcgga aaaccagcaa tcagcgagat tgattattca atcaagactt accgtggata
    22021 tgtccctgtg tcacaagaaa tgattgacga cgcagactat gacatcatgt ccattgttga
    22081 agacgaagtg ttcaatcaag gtgacaacac tgaattgtca ttagttacag ctgtcctcaa
    22141 aacagctacc caagcagatg cggctggatt tgatggtatt aaagatatct acaacaagaa
    22201 gcttaaatca atttataaag caagcatcgt tgtaactaag tcaatgtttg ctgcgcttga
    22261 caaagtgaag gacaaagatg ggcgctacat gcttcaaact gatgtggctt cacctactgg
    22321 ctattcattt ggtgggaaaa caatctacaa agtagatgac acagtgtttg gaaacgaagg
    22381 agatatgaaa ttcttcatcg gagatgttac tgagttcgtc aaagagtttg accgttctca
    22441 agtatccgtt aaatgggtga acaatgacat ttacggacaa ttgcttgggc tttttatccg
    22501 tttggatatt aagaaagcag atgaagaagc tggattcttc ggaacatata ctgatgttgt
    22561 agcttaagga ggtagcgtat gagctataaa gtaatccgtc ctttcaagga cttggctgat
    22621 cctgaaaatc atgactacgc tgttggcgat atctttcctc gtgagggata tgagccaaca
    22681 gatagcttta ccaatggcct tttgactggc gctaacactg ctggctctat cttccttgag
    22741 gttttgggag atgatgaacc taagaaacca gcgcctgaaa caaaagaagt gaaggaagag
    22801 cccgcagttg agcaggaaga aacagttgag gaaactgctg aagagtctgc tgaggaagtt
    22861 gaggaataga catggaccaa ggtcagcttt tagagttgct gaagcttaag ttgggtattt
    22921 caaccgactt gagagacaag ccgttaaaaa aaatcatttc aagtgtcatc actgaattga
    22981 ccgataatct cggtatcgag cttgttggtg agcgtgctga ccatgaaatg tttatcgttg
    23041 actatgccgc ttatcgttat gagggtgggg tggatatgcc acgtcacctt cagtggcgac
    23101 tgcataattt acagatagca tcaaagaaag aggtcaagaa tgtggaatca tgaaatcaca
    23161 ctgatctcca agaaagtaac aggtaaggat aagttactac aaccaatctc tgaagatgtt
    23221 gaagttactc tcttatgtcg caaaaagagg gtcactcgct ctgaatttta tcaggcgaat
    23281 caggtagggc ttaaaccgag cttggtcgtt gagattcgaa attttgagta tgagaatcaa
    23341 gagcttgcga agttcgaagg caagcaatat catatcttga aaacctatcc tattgattct
    23401 gaaattttag agttgacttt gtcagaggtg ttgaaatgag taatgacctt gctgatttga
    23461 tagcgaaaga gcttgcagct tactctgatg aggttactga agaagtggat aagattgcag
    23521 agcaagtgac tgatgagact gtggatgagt tgaaagagac aagtccgaaa cggtacggaa
    23581 agtatcgtag aagttggaaa aagaagaagt tggccaatgg ctcttttgtt gtgttcaacg
    23641 cagttgcaag tcttactcac atacttgaaa acgggcacct ttcaagaaat ggtggtcgtg
    23701 tcgctggtat cgtccacatc aagccagctg aagaaaaagc aattcagaac tttgagaagc
    23761 gaatcaagga gattgggaaa tgaagctatc agactttgct gctattttgg aacaggcaaa
    23821 cttgcctgtc acttatcgag cgtttaaaat tggaaacgct cctgacctac cttatctggt
    23881 ctattatgaa tcaagtccag tcatcaattc agctgacaac acggttaatc atcagattaa
    23941 gagcgtgaca gttgagctgg cttttgagag taaggatgaa gatttggaag aacgtctgga
    24001 agagctgtgg gcaaaccaca agctcttttt tgaagttcaa gaagaaacat ttatcgagac
    24061 tgaaagactc tatgtcaagt cttacacagt ctatctatac taaggaggaa tgacatgact
    24121 caagaaaata aagtaacctt tggcctagaa aatgtacata tcgcacctat caagacactt
    24181 gcagcagatg gagttatcac ttacggcgat gtttttcgtt ttcctggagc aatagagctg
    24241 atacttgata ctaaagggga aacaacccct atcaaagcag acaacaagga ttaccatttc
    24301 atgaattcaa acgaaggata tgagggtaaa cttaaaatcc cacacatcat tgatgaattt
    24361 gcgacaaaaa ttcttggtga aatcaaggac cctcaaactg gtgttatgac tgaaaaagca
    24421 gatgcgagct tgacagagtt cgcaatgatg ttccagtttg aaggcgacaa aaacaagact
    24481 cgctatgtga tgtactactg ttttgccagt cgcccatctc ttggctcaaa aactaagaac
    24541 gggacatcaa ccaacgaacg tgaacttagt ttcaaagcta gcccgcgtcc attggataca
    24601 gttgtcaagc gttctatcac atcagctgat gacaaggatg cgtatgacaa ctggttcaag
    24661 aaagtgtatg aacctactgc agttgcagct taaggagaag atctatgcgt aaaatcgttt
    24721 tggttggtga tcaggagtat gagttgggga ccaacggcta tactcctatt gcttacaagc
    24781 aacaatttgg aaaagattat tttcaagatt tgttctcgat gttgaaaaat caatcattca
    24841 tgaatgaatt gaacaagttg gaaaccgaca aggaattgac agcgactaat attgatattt
    24901 cgatgttgtc agattttgac atgacctttt tcaaccgtct tttttggacc tttgctaaat
    24961 ctgcaaatcc tcacatcaag ccttatgaac aattcttcat ggaaatggaa atcttcccga
    25021 ttcaggaagt tggacctgtg ctgatggaaa tgctaaatgc gagcatgacg acaaaaaagc
    25081 accagatgag tcagaatcag ctagcgaaga aatcttcaca gtagaatcct atctatcttg
    25141 ctgtaaagaa actggtcttt ctattgatga tctaaagcac atttcaatcg gaatggctct
    25201 ggattatcag acggattatg tgaatctacg gagcgaggat aagggtggcg aacggaaagc
    25261 cacgcaagct gattttgaca gtttttaaag aaaaatgagt gctgagagag cgattctgag
    25321 accaagttcc ttggtctggc tgcattatca gtggtagaag ttctctcagc gcttttctat
    25381 ttttttgaga aaggaggaaa tatggcagga aatatcaaag gtatcaaaat tgaaatcgat
    25441 ggcgacacgc aacccttgca gaaggcgctg aaaaatgtca ataaggccgc tactgatgca
    25501 agtcaggagt tgagacagat tgacaaggcc ttgaaatttg atacagggaa cgtaacgctc
    25561 ctgactcaga aacaagaggt cttacaaaag caagtttcga cgaccaagga gaaactggaa
    25621 accttgagac aagctcagtc tcaggtggaa cagcagttca aaaatggtga tatcggtgct
    25681 gatcagtacc gtgcctttca acgcgaagtc gaagttactc aaaacgtcct aaaaggatat
    25741 gagggtaagc ttgcaaatgt gaatcaggcg cttaatgaga atgggagtgc tactcagaac
    25801 aacaagaacc aattaaaaga gttgcaaaat gagcagagtc aacttgcttc agagatgagt
    25861 aaggtgacaa gttcattcaa actgcaagaa agcgctttgg gttcaaatgc tagtgaagcc
    25921 gagagaaatg ctcttgccca gaaaaagatt ggtgcccagt ctgagattgt aagtaaacag
    25981 atttcaaatc tagaacagca attggaaatc actaaaaaag aatttggtga gaactccaca
    26041 caagccaaca agatggaatc tgagctaaat caggctaaga ctgcttttaa tcatctcaat
    26101 gatgagatga agggaacaaa gtctgctgct gatagcactc aagaaagttt aagtgaaatc
    26161 tcaagaaatt taagagcaga actacttcaa cagtttagtg agaagttgag tgctatttca
    26221 gaaaagcttg tggaagtagg aaaagaagcg ttagaagcag ctgctcaaat gcaagctagt
    26281 aatgctcaat ttactaccgt tttcggagat atggaaaccc aagcaagaga agcgttgaat
    26341 gctattggtc aggaaatgga tattgtccca gagcgtttac aagggtcatt tactcagatg
    26401 gcttcatttg ctaaaacttc aggactagac actgcgcaag cattggacct gacttcccgt
    26461 gcaactaggg cagcggcgga tggcgcagct ttttacgaca agtccatcga gagcgtatca
    26521 gaaagcctac aatctttcct gaaaggaaac tttgctaacg atgccgctct tggaatctct
    26581 gcgacagaaa cgaccaggaa tgcagctgca aataaattgt acggaaagtc attcaaggac
    26641 ttgagcgaag cgcagaagca attgaccttg cttcagatgg tcgaagacgg aaataaactc
    26701 tcaggagctc ttggacaggc tgcaagagaa tcagacggcc tagaaaacgt gatggggaat
    26761 ctgaaacaag ctgggaccaa tgcattatct gctattggtc aacctcttct agaaatgatg
    26821 attcctgttt ttcaaacctt ggcaacgatt gtgaaaggtg tggccgagct gttcaattcc
    26881 ttgcctgatc cagtaaaaga ttttgttgtt attttaggaa cagttgtgac tgctgtaggg
    26941 gtcatagccc ccatattctt aaccttgcaa gcccttgctg agtttttaaa aatatctatt
    27001 ggagaaatga taattgccgc attgccaatt attggaacag ctattgcaat tgctgctgca
    27061 gttgctgcaa ttattgttat tgtaaaatat ctctgggaaa ctaacgaagg ttttcgagat
    27121 gcggtcacga ccgtttggaa tgctatacta gccgttatca atacagttgt ttcagaaatc
    27181 tctgatttca tcatgagtat attcgggacg gttgttactt ggtggacgga gaaccaggaa
    27241 cttatcagga caagtgctga gactgtctgg aatgccattt atacggtcat cagtacaata
    27301 ctggatatac ttggcccctt gctccaagct ggctgggata acattcaact gatcattaca
    27361 acaacttggg aaatcatcaa gatcgttgtt gagactgcaa tcaatgttgt ccttggtgtt
    27421 atccaagcag ttatgcagat cattactggt gattggtcag gagcttggga aactatcaag
    27481 ggagtgtttt ctactgtatg gcaagctatt caaagcattg ttcagactat tttctcagct
    27541 atccagagtt atatttcaaa tattctcaac ggcatttcag gaactgtatc aaatatctgg
    27601 aacagcatca aggacactgt ctcaaatgtg ttaaatgcta tatctagtac tgtatcaagt
    27661 gtttgggaag gtatcaagag taccatttca agtgctatca atggtgcaag ggatgctgtt
    27721 tcttcagcta ttgaagccat caaaggattg tttaacttca acatcagctg gccacatatc
    27781 ccactacctc acttttacgt gagtggttcg gccaatccat tagattggtt gagtcaaggt
    27841 gttccaagta ttggaatcga atggtatgcc aaaggcggta tcatgacgaa accaactatc
    27901 tttggaatga atggtaataa cataatggtt ggtggtgaag ctgggaatga agcagtattg
    27961 ccacttaacg acaaaacgct tggagccatc ggtcgaggta tcgctcaaac tatgggtgga
    28021 acttcaccaa ccatcaacat tactattact ggtaacaccg tcagagaaga agctgacatc
    28081 agtcggattg ctgatgaggt ggctcagcgt attgctgacg aattacaacg taggagacaa
    28141 ttgagaggag ggtttgcatg ataaagcata atgagcttgt gattgacggt gtgaggacat
    28201 cgtcttttcc atttaagatc attgtccatg actctccttc aatcgctcta ggagagagca
    28261 agacagctct cttggagcat ggtggtgtca gtggggcaat cgttcagaca aacaagcata
    28321 gggaactggt caagaaaact tatacgattt acttggtcaa acctactgaa gaacagatga
    28381 accaatttat gagtctgttt atccgtgaaa agttctggct agagagtgag cgagtcaaaa
    28441 caactcgtct ttggtgctat aaggtcaatg tgagcgacct tgaagaagtg caacctggtc
    28501 tttacatgac caaagcaacc ttcacttgcc atcctacaaa atactttaaa gactccgata
    28561 cacagagatt gacaagaagt gggactttga ccgttcaagg ttctgctctt gcctttccta
    28621 aaatcacaat cgttggtcag agcgcttctg aaacttcatt tacaattgct ggtcaggtca
    28681 ttcgtcttga acgactcact gagtcgcttg tgatggttaa taatcctgac aatccaagtt
    28741 ttaaaacaac aacagggaag ccagtcaaat ggtcagggga ttttatcaca gttgatccag
    28801 cgaaagtgaa gaatattggg gttgttttag gcccaggtat tcaatcgatt gaaatcgaaa
    28861 cggtttgggg gtgggcataa ttgctttatc tacttaataa agatgtaaga accgttcgat
    28921 ggaacgggga gccacttcat gaagcgactt cggcgattgt gaaagaaact atgaatggcg
    28981 attttacctt gactgtgaaa tatcctattt ctgattctgg tatttaccag ctcatccaag
    29041 aagatatgct gataaaggct ccgactcctg tcttaggagc gcagctattt cgtatcaaga
    29101 aacctgttga gcacaatgac catctggaaa tcacagccta tcacatttca gatgatgtga
    29161 tgcaacgatc tatcacacaa atgagtgtga ctagtcagag ttgtggcatg gctcttgctc
    29221 gcatggtaca aaacaccaaa acggctcttg gagacttctc attcaacagt gatatccagg
    29281 accgtaggac attcaacacg actgagacag aaaccctgta ctctgtattg ctggacggca
    29341 agcatagtat cgccggaacg tgggaaggcg agctggtgcg tgataacttt gcgatgactg
    29401 taaagaagag tcgtggtgag aatcgtggtg ttgttattac aacacataag aatctgaagg
    29461 actaccaacg aaccaaaaac agtcaaaatg ttgttacaag gattcatgct cgatccacat
    29521 ttaagcctga aggtgctgaa aaggaaacaa ctatcagagt gactgttgat agtcctctta
    29581 ttaattctta tccttatata aacgaaaaag agtatgagaa caacaacgca aaatccgttg
    29641 aagagttgca gaagtgggca cagtctaagt tctcaaatga gggaattgac aaggtctctg
    29701 atgctatcaa aattgaagct tatgaacttg atgggcaagt ggtccatatg ggcgacacgg
    29761 tcaatctcaa gagctggaaa cataatgtcg atgcattcaa gaaagctatt gcttatgagt
    29821 tcgatgcctt aaaagaagaa tacatctctc tgactttcga tgataaggca ggtattggtg
    29881 gttctagatc ttctggtggc ctatctagcg cagccgatgc aattcttgga gtgacagaat
    29941 ctgcacaaga aatcgccctt gaaaaggctc ttcaaaatgc tgacttagac tttgatcata
    30001 aggctggatt gcttagacag gaaatttctg acgatattga actggccaaa gccagagctg
    30061 aagaagtcaa gagagaactg tctgacacta tcaatcagcg atttaatagc tttgacaacg
    30121 ggccattgaa agaaactaag cgcaaggctg aggaagcttt gcgaaatgct ggcgcaagta
    30181 ccctgcttgc acaggaagct aagcggattg ggctggattc tgtcgctaga cttgaagcgt
    30241 ttaagtcgca gactacgagc gcacaaacgg ctctgtcggg tgacttggac gctctgaaac
    30301 ggactatcgc gaatgatatt cgaccgaagc aagcacaggc tgaagctgag attgccaagc
    30361 aagctgaagc acttagccgg actaaaaatg aactggctgg cgcaagtacc ctacttgcac
    30421 aggaagctaa gcggattgag ctggattctg ttgctagact tgaagcgttt aagtcgcaga
    30481 ctacgagcgc tcagacggct ttgtcaggtg acttggatgt tctaaaacaa actatcgcaa
    30541 acgatattcg accgaagcaa gcacaggctg aagctgagat tgccaagcaa gttgaagcac
    30601 ttagccggac taagaatgaa ctggctggcg tgaagtcagc gcaagcgacg tataaggaga
    30661 cgacgactcg tagactgtca gaactgacca acttggccaa tggtaaagcc agcaagtcag
    30721 aacttacgca aacagctgag gagctggcta gtcggattgc gagtgtgcag gcaggtagtt
    30781 cacggaatta cttcaggaat tcacgttcaa gaacgttcac aacaggaggt caagcggtat
    30841 acgactatcg aacattcata gttcctgatt tctggaagaa cagtgacagg ttcaagcgtg
    30901 attatgttcg catatctttt gatgtgactt tccctgtcgc cctagtaaat gacatgcctg
    30961 ctatggtgca ttttagtgct catccatggt atgcctacag aaacttaatt tttaaaggtg
    31021 gaactgtcga acgccaacat tttgagttta cgattgactt gtctagttct tctgaggact
    31081 atcagactaa taatgtgttc attcgttttg gtactaatta tggatttcct gctggtctgc
    31141 aggtcgtcat tgagaacgct atgttatcgg ttggtaatta ttttccagcc tatcaaccag
    31201 cgtatgaaga ccaagaagac cgtgtctcag tagtcgaatc caactttaaa cagcgtgctg
    31261 attcactcga cgctggtgta agaagcttga ctgaaggcct tagaaccaaa gcggatatca
    31321 gctcactcaa tgtgactgct gaaaatatcc ggcaatctgt gaagagcctt gagacagata
    31381 cgcagaacaa gctaaatcag aagttgagtc aggctgaatt tgaggtgcga gccggctcta
    31441 tccgtcagga aatcctgaac gcaaccaagg ataaagccag caagtcagaa ctcacgcaga
    31501 cagctgagga gctggctagt cggattgcga gtgtgcaggc atccggtcga aatctattct
    31561 tgaactcact attcaagcag gatattccaa aaacaggaat ttggacaacg agtacatata
    31621 cggctactat cgatagcgaa agtaagtatc ttggacacaa ggctcttaaa attataggtt
    31681 tgaatccatc tggccgtgat ggaggtaatc ccaaggttac ttatccagct ctgggtcaat
    31741 tcgggaaagt aattcccgga agtacgacta atcaagatgt aaccattagt ttttatgcta
    31801 aggcaaataa aaatggaata atgctaagat ctcgattagg gaatatcgga tataaaactg
    31861 gaaatgtgac attgtcgaca gaaattaagc gatatgttgt ccatattcca aaaggttgga
    31921 caaacgaatc caagcagacc acaaatgaat ggttgttcaa tttcaaccag gaaggaacca
    31981 tttggatttg gatgccgaag tttgaaataa gcgatgtaga tacttcttat tcagaagctc
    32041 ctgaagatat agaaggtcag atttcaacag ttgaatcgac cttcaaacaa cgagccaact
    32101 aactcgacgc tggtgtaagc cgtctgactg aaggccttag aaccaaagtg gatatcagct
    32161 cactcaacgt gactgctgaa aatattaggc agtcggtgaa gagtcttgag acagacacgc
    32221 agaacaagct aaatcagaag ttgagtcagg ctgaatttga ggtgcgagca agcggaatcc
    32281 gtcaggaaat cctgaatgca accaaggaca aggctgacaa gaccttggta acagcggagg
    32341 ctgggaagtt gagagaggag ctgacaagtc tgtcggttgg cgagaatctg tttgtaaact
    32401 cagattttaa aaatctgagg gataacggac agcgttatac agctaacggc aagacctatc
    32461 aaaacatgat tgcgccttac tggtacaatc cgtacaatgc tggtattcca aatgctcaaa
    32521 atatccagca tgggtatttt gacacggaaa cgtttagtga tactgtcttt gcctttaacg
    32581 agagcgacgg ctcccgacac tggaaagcat tgtcaactga ttttaaaatc ggagtcatct
    32641 cagctggaga gtattacttt tcagctgatt tgtatgcgac agatttaggc actcatatca
    32701 aatttggatt ttactatcac aactcgactg gcaaactcaa tttttacgca ggtcgaacaa
    32761 aaattgaagt tactgaaaaa ggccgttgga ctaggctagg aattgactta aaggtcaatg
    32821 atgacattga cctgacaaaa aaagtccaat tttacattta cggctataat tttgctagca
    32881 actcaatttt gtaccttaaa aagcctaaag tctcgaaagg tcgcttaaaa agcgattgga
    32941 gcccagctct ggaagacacc gaaggcctca tcactgaggc taaggcaacc tttgagcgga
    33001 cagctcaggg cttgcgaacc gacttatcag ctattcagga atatgtaaat aaagacggtc
    33061 agcgacagga agccctacag cgctatactc gtgaggagag cacgagacaa gcgacagcag
    33121 tccgtgagct ggtcaatcgt gatttcgttg gtaaggctac ttatcaagaa gatgttaagg
    33181 gtatcaatca gaggattgaa gctgttaaaa ctagtgcgaa taaagacatc gctagtcaaa
    33241 tcgctagcta tcgtcaatct gtagatggta agttcacgga tatttcaagt cagataacta
    33301 cttataagca agatgtgggc ggtcaaatca gtggtctatc aaatagactt acaagcagtg
    33361 agcaaggaac cactactcag atttcaaata tttcaaatcg gataaacagt aataaacaag
    33421 gcacagataa tcagatttca aatttaaaga ctcaggtcgc tacaaacaag gataatgctg
    33481 aacgacaaat gggtagaata tctgatcagg tttctgcaaa caaagcgaat gctgatagtc
    33541 aatttgcgaa tgtgaccaat caactagcgc gaaaagtaga gactactgac ttccagcgtg
    33601 ttaaggaaac cagtaaactt tacgagcgga ttttgggcaa tactgaaaat ggaattgcgg
    33661 ataaggttgc tcgcatggct ctgaccaatc aactgtttca ggttgaggtt gggaaatata
    33721 gtgtaagcgg ccctaacctc attaagaata gtgattttaa aaatggtacg aatgaatggg
    33781 gctcaactca aaatttagga agattggtta agcatagctt ttatcacaac gggcagaaag
    33841 accttatgcg tttaagtaat gcaactaaaa acgaaaactt tttgtatagt caccgtttta
    33901 atcttgaacg aaatactgac tatgtactga attttagagg atttaacaac agtgctctcg
    33961 caagctatga tgtttatatt ttgggacgaa gagcaggcga gagcgatgga ttcacaatcg
    34021 ttaagaaagt tgttagcagc aagaaactat ctacctctag atgcgaagat gtctcagtaa
    34081 cttttaattc cggagaaatg gataatgctt acattcgttt tgataacaat ggctcatcat
    34141 caggaacagc tgatttgtat attacagaag ttgacttgta caaaggttat aaacctagaa
    34201 catggcaacc acatccagaa gatgcagtcg cagatgcgaa taagaagctt gaagccacgc
    34261 aaacaaaaat gactcaacta gctggctcat gggtagttga aaacatcaac tcggctggag
    34321 atatcatctc tggaatcaat cttggcgcca atggacataa ccgctttgtt gggaaattga
    34381 cccacatcac tggagagacc ctgattgaca gagcagtcat caagtctgcc atggttgata
    34441 agctcaaaac ggccaatttt gaagctggtt cggtcacgac tacgatatta gacgctgaag
    34501 cggtcacggc tgataaagtg agatttgatg ctgcgtttat tagaaaaatg attgcaaatg
    34561 acgcttttat tgaccaactg acatctaaac gtatcttctc tactaaggtt gagtccgtca
    34621 tttctagttc aaccttccta gaagcctatc aaggccgaat cggtggattt acacttggtc
    34681 aatttgatca gggtggcggt cgctggattt caggtgtcaa tcagttctct gttggtatgg
    34741 ggaatggtgc cgggcatggg gtgccggaca gccttctggg cgaactgggg aaataattgg
    34801 aactatgccg gacctaaagc atggaacgtc aatactgatg ggaaaatgta ctgtaggaat
    34861 gaagtcggtt tttatgatca agtggatttt tcgaattcat cgagagcaaa cttctatggg
    34921 aatactactt tttctcgttc tcctgtgttt tcaaatggta tcgaacttgg aagtaaagat
    34981 gtgcttggtg atggttggaa tcccaaaggc ggaaggaatg cggttgtttg gtggaatcag
    35041 gtcggtagcg gtagcgtgaa gtattggatg gaacaaaaat cagacagacg cttaaaagag
    35101 aacatcacag atacagctgt gaaagccttg gacaaaatca acagattaag aatggttgca
    35161 tttgatttca tcgaaaataa gaaacacgag gagattggtc taatagctca agaggctgaa
    35221 accatcgttc caagaattgt ctcacgagat cctgagaatc cagatggcta tctacatatc
    35281 gactataccg ctttagttcc ttacttaatc aaggctattc aagaattaaa tcaaaaaata
    35341 gaaaaaatgg agaaaacaat agcatgaata acaacatgtt gaccaatatc gcacttaaag
    35401 caattcagga gtttgctctt gaaaatagaa aacgaacaca cagattggag aacttagaaa
    35461 atgaacacag aacagcttaa ccaagcctta caaatgacaa ttcgtgaaat gtcaacaact
    35521 tcaacagatt cgatgattgc aagtaatttc ttgagtattc agttgaatga gcaaagggaa
    35581 gagaatcaaa gacttcaagc acgagtggat gagctggaag ctctgcttga tgaacaaact
    35641 aaaccagcag acaaaggaga atagacatgg cagaaacaat tcaaaacaca gataacttac
    35701 tagaccttac aaaaatcaca gaaccatttg atcttgcgag cgctttgcgc tacatgaaag
    35761 aaaatggaga gttcattcgt tgcaagaatg taagcgatga cttctatatg tatcgtgatg
    35821 ttcaaaaacg tcctgtgatc gtaaatggcc gtcgccaatt caaggatgtt gaaactgttt
    35881 gggcgttcaa ccagtggggg ggggtacaat cacaacaatc aacgtagccg ttctgttgaa
    35941 tcatgaattc tatatcatga aatttgatgc agagggcaat cctgactgga cggatccaac
    36001 ggtaaaacct aaagaatagg aggtgtgtat gcaaattgaa tttttcaatt ttctaagaag
    36061 tgtcgtacag actgaagatg gtttggtctt gtacgctcta gcactgattg tctcaatgga
    36121 aatcattgat tttgtgacag ggacgattgc ggcgattatc aatcctgaca tcgagtacaa
    36181 gagcaaaatc ggcattaacg ggctccttcg taagatttca ggggttctct tactgatgat
    36241 cctcattccg gcgtccgttt tgttgcctga aaagacaggt tttgtattct tgcactcaat
    36301 ctatctcggg tacatcgcat ttacttttca atctctcatt gaaaattacc gcaaattaaa
    36361 aggaaatgtt actctttttc agccgattgt aaaagtattt cagcgattac ttgaaaaaga
    36421 tgatgatacg aaaaaaggag aataacaaat gcaacaaatt actgaaatca ttactaatgg
    36481 agcaatcagc atcctagtca ttttggcagg ggtggtagtt agggtagtca aggaatacct
    36541 cgtcaaaaaa ggtggagaaa agactatcaa gattgttgaa atcttggcca agaacgcagt
    36601 taatgccgtg gagcaggtag ctgctgaaac tggctacaag ggagatgaaa aactggcaca
    36661 ggctcgcgct aaaattcgtg cagagctgac caaatataat atcagtatga cggacaagga
    36721 cttggacacc tttgtggagt cagccgtgaa gcagatgaac gacgcttgga aaggacaaga
    36781 gtaatggata tcgatagaaa cagactacgt acaggcttgc cccaggttgg ggtgcagcct
    36841 tatcgacaag tacatgctca ctcaacaggc aaccgtaact caaccgctca aaatgaagct
    36901 gattaccact atagaaagga ccctgaacta gggttctttt cacatgttgt cggaaacggc
    36961 cgcatcatgc aggtaggacc tgtgaacaac ggaagttggg atgttggggg cggttggaat
    37021 gctgagagtt atgcagcggt tgaactgatt gaaagccatt caactaagga agagtttatg
    37081 gctgactatc gcctctatat cgaattgcta cgcaatctag cagatgaagc aggtttgccg
    37141 aaaacgcttg atacagggag tttagctgga attaaaacgc acgagtattg cacgaataac
    37201 caaccaaaca accactcaga ccacgttgac ccttatccat atcttgcaag ttggggcatt
    37261 agccgtgagc agtttaagca agacatcgaa aacggcttga gcgctgcgac aggctggcag
    37321 aaaaatggta ctggctactg gtacgtacac tcagacggct cttatccaaa agacaagttt
    37381 gagaaaatca acggtacctg gtattatttc gatggctcag gctatatgct ttcagaccgc
    37441 tggaagaagc acacagacgg taattggtac tactttgacc aatcaggcga aatggccaca
    37501 ggctggaaga aaatcgctga gaagtggtac tattttgatg tagaaggtgc catgaagaca
    37561 ggctgggtca agtacaagga cacatggtac tacttagacg ctaaagaagg cgccatggta
    37621 tcaaatgcct ttatccagtc agcggacgga acaggttggt actacctcaa accagacgga
    37681 acactggcag ataagccaga cttcacagta gagccagatg gcttgattac agttaaataa
    37741 atagaaagga aactttctaa attgttcttt caccgcaggc tcaggcttgc ggtttttttg
    37801 tttgtctgaa tcaagaaagc gtctaaccaa ccgacaccaa tgtcggtagc aaaataaatg
    37861 gtttgcctaa aaaattagag ttaagttcta tttttcaaaa acacgcattt tgaacgatta
    37921 gaaacagaaa tctaaatcct attgttcaaa aaaacgttta catgaaaaat agggaggtgt
    37981 tttgttaaaa ataaaaacag tgatcgaaat cactgcttat cagttgtagc aaattcataa
    38041 agtttttctg ctgtgagaag tgccattttg tccatgcttg tttttccttt tctgaggtca
    38101 gaaacagtag tccatggaac tccagcacct tgggaaatag cagatgtaga catcgaactg
    38161 tctaacaatt cttgaataac ttctctcatc ttatttgtcc tttttatttt ttagataaat
    38221 atatacattg attgcaatta taaaaatagc tattgcacta accattgcat ttcctctttc
    38281 catttgataa aatagaggtg taaggggctt tcgccccaac ctcttagcgt ttaccttttt
    38341 ctttgacggg atttcggttt acgctttttg ttttgccttg cgaccgttat tgcggtcact
    38401 agacttgcga tagcagttac cgtttcagga atattgtcta ttgccttttc aagtaacctg
    38461 agccaatctt ctttgttcaa cttcatcacc ccctttcctt atcttgatta tattatatca
    38521 cggtacaccg agaaagtcaa gcgttttgat gaagtttttt ttaatttttt caaaaaaaaa
    38581 tagaccttgt ccagaggtcg gggagttgga gggggcaccc tccaaaagca ttgatttaat
    38641 aaggttttat tttacctttt tcataataat ctccctatag agtcaccgca ttcggtggct
    38701 ttttttgtgt tgggattcat gatataataa taaaatcgat aagtaggaaa agagaaaaga
    38761 gatgtattat acgcttgaag aaaaagaagt ctttatgagg gaggctttga gagaggctga
    38821 gattgctctt gaacacgatg aaattccaat tggttgtgtg attgtcaaag atggggaaat
    38881 cattggtcgt gggcataatg cgcgtgagga attacagcga gcggttatgc atgcggaaat
    38941 tatggctata gaggatgcga acttgagtga ggagagctgg cgcttgctgg attgcacact
    39001 ttttgtgacc attgaacctt gtgtcatgtg tagtggagcg attgggcttg cccgcattcc
    39061 aaatgtggtc tatggggcta aaaaccagaa atttggcgct gctgggagtt tgtacaatat
    39121 cttgacagat gagcgtctca atcatcgtgt ggaggttgaa ataggaattt tggaagatga
    39181 atgcgcagct atcatgcagg atttttttag aaatagacgg aaaaaataat tttgctttta
    39241 aaatgaatag gaatgtgata taataaatag tggagcaaca gttctgcgtg aagcgggtca
    39301 ggggaggaat ccagcagccc taagcgattt gaattgtgtg ctcttttttt cgtgcttttt
    39361 ccgaataaat aagatagaat aatctagaat aaatgataat agaaaagaga aaattatgaa
    39421 aattcgtggt tttgaattgg tttcgagttt tacagatgaa aatttattgc ccaagcgtga
    39481 gacagcgcat gcggctggtt acgacttaaa ggttgctgtg cgtacagttg ttgcgccagg
    39541 agagattgtc ttggttccga caggggttaa ggcttatatg cagccgactg aggttctcta
    39601 cctctatgat cgttcttcaa atcctcgtaa gaagggcttg gttttaatta actcagttgg
    39661 ggtcattgat ggggattatt atggaaatcc tggaaatgaa gggcatattt ttgcgcagat
    39721 gaagaatatc acagatcaag aggttgttct tgaagttggg gaacgtattg tccaggctgt
    39781 ttttgctact ttcttaattg cagatggaga tgcagctgat ggcgttcgaa ctggtggatt
    39841 tggatcgaca gggcactaga atgaagatta tctttgtacg tcatggggag ccagattacc
    39901 gtgagttaga ggagcgttct tatataggat ttgggataga tttggcaccc ttgtctgaga
    39961 tgggacggca gcaagtccag aaattgagca aaaatccttt actctcgtca gctgaaataa
    40021 tcgtatcttc tgcagtcaca agagctttag aaacggcttc gtatgtggtc tgtgctacgg
    40081 gtcttccttt aagagtagag cctttattac atgaatggca ggtctataaa acaggaatag
    40141 aaaactttga aacagctaga agactgtttt tagaaaacaa gggggagttg cttcctaata
    40201 gtcctattca atatgagaca gctacggaaa tgaagtctcg gtttctagaa tgtatgtcta
    40261 agtatcgaga acatcagact gtggtagttg ttgctcatcg aatgctcatg cgccagtttg
    40321 tgccaaatga gaagattgat ttttgccaag tgattgagtg tgagttagag atatagaaag
    40381 aggtttgtca tcgcaaagaa aaaagcgaca tttgtatgtc aaaattgtgg gtataattcc
    40441 cctaaatatc tgggacgttg ccccaactgt gggtcttggt cttcttttgt ggaagaggtt
    40501 gaggttgccg aggtcaagaa tgcgcgtgtg tccttgacag gtgagaaaac caagcccatg
    40561 aaactagctg aggtgacttc catcaatgtc aatcgaacca agacggagat ggaggaattc
    40621 aaccgtgtgc ttggaggcgg agtggtacca ggaagtctcg tcctcatcgg tggggatcct
    40681 gggattggga aatcaactct tctcctacaa gtctcaaccc agttgtccca agtggggaca
    40741 gttctctatg tcagtgggga ggagtctgcc cagcagatta aattacgtgc agagcgctta
    40801 ggtgatattg atagtgagtt ttatctctat gcagagacca atatgcagag tgttcgtgca
    40861 gaagtggagc gtatccagcc agacttcttc attattgact ctatccagac cattatgtct
    40921 cctgagattt caggggtgca ggggtctgtt tctcaggtgc gtgaagtgac cgctgaactc
    40981 atgcagttgg ccaagaccaa taacattgcc atctttatcg taggtcatgt gaccaaagaa
    41041 ggaaccttgg ctgggcctcg tatgttggag catatggtgg atacggtgct ttactttgaa
    41101 ggggagcgtc accacacctt tcgtattttg agagcggtca aaaatcgttt tggttccact
    41161 aatgagattg ggatttttga gatgcagtcg ggcggcttgg ttgaggtact caatccgagt
    41221 caagttttcc tagaagagcg tttggatggg gcgactggtt cctccatcgt tgtaaccatg
    41281 gaagggacgc gtccgatttt ggcggaggtt caggctttag taacaccgac catgtttgga
    41341 aatgccaagc gtactacgac aggacttgat tttaaccgtg ctagcttgat tatggctgtt
    41401 ttggaaaaac gggcagggct tctcttgcaa aatcaggatg cctatctcaa atctgctggt
    41461 ggtgttaaat tggatgaacc tgccattgac ttggctgttg cagttgctat tgcttcgagc
    41521 tacaaagaca aaccaactaa tcctcaggaa tgttttgtcg gagaactggg cttgacagga
    41581 gagattcggc gcgtgaatcg tattgagcaa cgcatcaacg aagctgctaa actgggcttt
    41641 actaagattt atgtacctaa gaattccttg acaggaatca ctctgcctaa ggaaattcag
    41701 gtcattggcg tgacaacgat tcaggaagtt ttgaaaaagg tctttgcata atccgtgaca
    41761 aattctctta aaaatgataa gataggagaa atatttgact atcaaatttt caaggaggga
    41821 atcgtgtcgt attttgaaca gtttatgcaa gccaatcagg cttatgttgc cctacatggg
    41881 cagttaaatc tgccacttaa acccaaaaca agagtagcta ttgtgacctg tatggactct
    41941 cgtctgcacg ttgcgcaagc tctgggcttg gcacttgggg atgctcatat cttgcggaat
    42001 gcaggtggtc gagtgactga agacatgatt cgttcgctag ttatttccca gcaacaaatg
    42061 gggacaagag agattgtggt attgcaccat acagactgtg gtgctcagac ctttgaaaat
    42121 gaaccttttc aggagtattt aaaagaggaa ttaggtgtag atgtgtcaga ccaggatttc
    42181 ttgcccttcc aagatataga agagagtgta cgcgaggata tgcaactgct tatcgagtct
    42241 cccctaatac cagacgatgt cattatctct ggtgccattt acaatgttga tacaggaagt
    42301 atgacagtcg tagaattata aatacttcat ttagaaagaa agtgtatgaa gaaaagcagt
    42361 attttattgc tatgtattgg tttacagtat gaaaccatct actatacgga cggttcgagg
    42421 tcaggtgcgg aatatggact aatgggaatt tctatctttc tagctctctt ttacatgatt
    42481 ccggctcttt attttctctt ccgtattggg aaaaatggga attgccaaag aaggttttga
    42541 ttctgtcttt attgggaggg atgttccttt caggctggtt gtctagtttt gctaatactt
    42601 atatccatga tttactgggg gttcttttcc cagatagtac atttttaaat gcctttgaaa
    42661 gtgctattgt ggctcctttg gtagaagaac ccttgaaatt attgccactt gtttttgttt
    42721 tggctttgat tcctgtgcga aaattaaaat ctttgttttt acttggaatt gcttccggtt
    42781 tgggattcca aatgattgag gatattggtt atattcgtac ggatttgcca gagggctttg
    42841 actttactat ttcgcgaatt ttagagcgta tcatctcagg aattgcctct cactggactt
    42901 tttcaggtct agctgtagta ggtgtttact tgctttacag agcctataaa ggacagaagg
    42961 ttggcaagaa acagggcctt atttttctag gtttagcctt gggaactcac ttcttgttta
    43021 actctccttt tgtggagttg gaaacagagt tgcctttagc gattccagtg gttacggcta
    43081 ttgctctcta tggtttttat catgcttatt gctttgttga gaaacacaat gagttgatga
    43141 cctagaatat ttttcaaaag aatgatgcaa gggtacaaat atggtgccct tcttttattt
    43201 ttgattgaaa aatagtgcaa aaagcgctac aatggtagat ggaaaatctt gtgaaaggca
    43261 caagttatac atatataccg gaggaaatca tgtctttttc tgatttaaag ctgtttgccc
    43321 tttcttctaa taaagaattg gcagaacgtg tggcgcagga gattgggata gagttgggga
    43381 aatcaagtgt tcgccaattt tcagatggag agattcaggt caacattgaa gaatcaatcc
    43441 gtgggaaaca cgtctttatc ttacaatcaa ctagttcgcc tgtaaatgac aatctgcttg
    43501 aaattttgat tatggtagat gctttgaagc gtgcgagtgc agaatctgtc aatgttgtca
    43561 tgccttacta tgggtatgca cgtcaggata gaaaggcgag agcgcgtgag ccaatcactt
    43621 caaaacttgt cgcaaatatg cttgaagtag ctggagtgga tcgtttattg accatcgact
    43681 tgcatgctgc gcaaattcaa ggattctttg atattcctgt ggatcatttg atgggtgctc
    43741 ctctgattgc agattatttt gagcgtcgtg gtatggttgg ttctgactat gtggttgtca
    43801 gcccggacca tggaggggtg actcgtgctc gtaagttggc agaatttttg aaaacatcta
    43861 tcgctattat tgataaacgt cgtagcgttg ataagatgaa tactagtgaa gttatgaata
    43921 tcatcggtaa ggttgaaggc aagacttgta tcttgattga tgatatgatt gataccgctg
    43981 gaacgatttg tcatgcggca gatgctcttg cggaagctgg tgctgttgaa gtctatgcaa
    44041 gctgtacgca cccagttctt tctggtcctg ctacggacaa tatccaaaaa tcagctatta
    44101 agaaattggt tgttttggat accatctatc tgccagaaga gcgtttgatt gataagattg
    44161 agcagatttc aatcgctcat ctcctagggg atgctatcgt acgtattcat gaaaaacgac
    44221 cactttctcc acttttcgat attgagaaaa aaatttaatg accaagcctg agatgattct
    44281 caggtttttt cgtctttttt ccgaataaat agatagtagc ggtgaatcta gtaaagctag
    44341 atttaaaact gtgatataat aaaaagagaa gaaatatgac tgtacgtcat cagaagtttc
    44401 agcgaccatc atttttgaac agtgatagca cttgaatcga cgctttctaa ggagaattct
    44461 agtaggcata ccagtcgttt caagataagg aattttagaa ggttttt
//
LOCUS       DAVBOH010000013        43028 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOH010000013 DAVBOH010000000
VERSION     DAVBOH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.013"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            35..105
                     /locus_tag="VQ873_000768"
     tRNA            35..105
                     /locus_tag="VQ873_000768"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:67..69,aa:Gly,seq:tcc)
     gene            141..214
                     /locus_tag="VQ873_000769"
     tRNA            141..214
                     /locus_tag="VQ873_000769"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:175..177,aa:Ile,seq:gat)
     gene            221..308
                     /locus_tag="VQ873_000770"
     tRNA            221..308
                     /locus_tag="VQ873_000770"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:255..257,aa:Ser,seq:gct)
     gene            complement(434..1369)
                     /locus_tag="VQ873_000771"
     CDS             complement(434..1369)
                     /locus_tag="VQ873_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3107072.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1366..2226)
                     /locus_tag="VQ873_000772"
     CDS             complement(1366..2226)
                     /locus_tag="VQ873_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3107073.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2334..4496
                     /locus_tag="VQ873_000773"
     CDS             2334..4496
                     /locus_tag="VQ873_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3107074.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4588..5847
                     /locus_tag="VQ873_000774"
     CDS             4588..5847
                     /locus_tag="VQ873_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3107075.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5861..6727
                     /locus_tag="VQ873_000775"
     CDS             5861..6727
                     /locus_tag="VQ873_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3107076.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6741..7574
                     /locus_tag="VQ873_000776"
     CDS             6741..7574
                     /locus_tag="VQ873_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3107077.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7575..7655
                     /locus_tag="VQ873_000777"
                     /pseudo
     CDS             7575..7655
                     /locus_tag="VQ873_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7932..9374
                     /gene="gtfA"
                     /locus_tag="VQ873_000778"
     CDS             7932..9374
                     /gene="gtfA"
                     /locus_tag="VQ873_000778"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3107078.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9512..10705
                     /locus_tag="VQ873_000779"
     CDS             9512..10705
                     /locus_tag="VQ873_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3107079.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11392..13371
                     /locus_tag="VQ873_000780"
     CDS             11392..13371
                     /locus_tag="VQ873_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107080.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVEVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13438..14934
                     /locus_tag="VQ873_000781"
     CDS             13438..14934
                     /locus_tag="VQ873_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107081.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14934..15860
                     /locus_tag="VQ873_000782"
     CDS             14934..15860
                     /locus_tag="VQ873_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107082.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15869..16936
                     /locus_tag="VQ873_000783"
     CDS             15869..16936
                     /locus_tag="VQ873_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107083.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16947..17873
                     /locus_tag="VQ873_000784"
     CDS             16947..17873
                     /locus_tag="VQ873_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107084.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18364..18879
                     /locus_tag="VQ873_000785"
     CDS             18364..18879
                     /locus_tag="VQ873_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3107085.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            18901..19302
                     /locus_tag="VQ873_000786"
     CDS             18901..19302
                     /locus_tag="VQ873_000786"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107086.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19314..20191
                     /locus_tag="VQ873_000787"
                     /pseudo
     CDS             19314..20191
                     /locus_tag="VQ873_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20204..21007
                     /locus_tag="VQ873_000788"
     CDS             20204..21007
                     /locus_tag="VQ873_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3107087.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21040..21750)
                     /gene="treR"
                     /locus_tag="VQ873_000789"
     CDS             complement(21040..21750)
                     /gene="treR"
                     /locus_tag="VQ873_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3107088.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21935..23902
                     /gene="treP"
                     /locus_tag="VQ873_000790"
     CDS             21935..23902
                     /gene="treP"
                     /locus_tag="VQ873_000790"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3107089.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24080..25705
                     /gene="treC"
                     /locus_tag="VQ873_000791"
     CDS             24080..25705
                     /gene="treC"
                     /locus_tag="VQ873_000791"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3107090.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25847..26095
                     /locus_tag="VQ873_000792"
     CDS             25847..26095
                     /locus_tag="VQ873_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3107091.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26302..27096
                     /gene="racE"
                     /locus_tag="VQ873_000793"
     CDS             26302..27096
                     /gene="racE"
                     /locus_tag="VQ873_000793"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3107092.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27093..28064
                     /locus_tag="VQ873_000794"
     CDS             27093..28064
                     /locus_tag="VQ873_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3107093.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28040..28561
                     /locus_tag="VQ873_000795"
     CDS             28040..28561
                     /locus_tag="VQ873_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3107094.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28558..29019
                     /locus_tag="VQ873_000796"
     CDS             28558..29019
                     /locus_tag="VQ873_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3107095.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29010..29750
                     /gene="xerD"
                     /locus_tag="VQ873_000797"
     CDS             29010..29750
                     /gene="xerD"
                     /locus_tag="VQ873_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3107096.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29750..30478
                     /locus_tag="VQ873_000798"
     CDS             29750..30478
                     /locus_tag="VQ873_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3107097.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30497..31066
                     /locus_tag="VQ873_000799"
     CDS             30497..31066
                     /locus_tag="VQ873_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3107098.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31053..31775
                     /locus_tag="VQ873_000800"
     CDS             31053..31775
                     /locus_tag="VQ873_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3107099.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31775..32017
                     /gene="yidD"
                     /locus_tag="VQ873_000801"
     CDS             31775..32017
                     /gene="yidD"
                     /locus_tag="VQ873_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3107100.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32242..33207)
                     /locus_tag="VQ873_000802"
     CDS             complement(32242..33207)
                     /locus_tag="VQ873_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107101.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33303..34055)
                     /locus_tag="VQ873_000803"
     CDS             complement(33303..34055)
                     /locus_tag="VQ873_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3107102.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34052..35008)
                     /locus_tag="VQ873_000804"
     CDS             complement(34052..35008)
                     /locus_tag="VQ873_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3107103.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VKKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34998..35957)
                     /locus_tag="VQ873_000805"
     CDS             complement(34998..35957)
                     /locus_tag="VQ873_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107104.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36380..37081)
                     /gene="galE"
                     /locus_tag="VQ873_000806"
     CDS             complement(36380..37081)
                     /gene="galE"
                     /locus_tag="VQ873_000806"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3107105.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37483..38547
                     /gene="pepA"
                     /locus_tag="VQ873_000807"
     CDS             37483..38547
                     /gene="pepA"
                     /locus_tag="VQ873_000807"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3107106.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38569..38865
                     /locus_tag="VQ873_000808"
     CDS             38569..38865
                     /locus_tag="VQ873_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3107107.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39547..39990
                     /locus_tag="VQ873_000809"
     CDS             39547..39990
                     /locus_tag="VQ873_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3107108.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            39994..40758
                     /locus_tag="VQ873_000810"
     CDS             39994..40758
                     /locus_tag="VQ873_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3107109.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40773..41501
                     /locus_tag="VQ873_000811"
     CDS             40773..41501
                     /locus_tag="VQ873_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107110.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41494..43014
                     /locus_tag="VQ873_000812"
     CDS             41494..43014
                     /locus_tag="VQ873_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3107111.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12454 a         7975 c         9675 g        12924 t
ORIGIN      
        1 ttccgtctcg cgccatttta ttgatagtat ttatgcgggt gtagtttagt ggtaaaacta
       61 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgctttgaa ctttgttcaa
      121 attaccaagt tttttaactt gggcgcgtag ctcagttggt tagagcgcac gcctgataag
      181 cgtgaggtcg gtggttcgag tccactcgtg cccattaatt ggagaattac tcaagaggct
      241 gaagaggacg gtttgctaaa tcgttaggtc gggtaactgg cgcaagggtt cgaatccctt
      301 attctccgtt ttaatgagag tctgtaactc tcttttttat ttttagagcc aataaaactt
      361 cagatccgta aaacttaatt gaattactaa tctgaagtta tttttatatc gtttatatta
      421 taattgtgtt attttacttc caactattga gagaaatttc gccactattt agccagattt
      481 cttttccgtt atcacattga actaaaagtt ttccattttc tgagatgtct ttagcaagtc
      541 ccttgtagtc tttttgctct agtgtgaaag tgacttcttt tcctagaatg aatgactgtt
      601 ttttgtatag gtataatagc tcttctgctg gtgtttcgaa gaaagcacgc cagatttcta
      661 tgatcaattc attccttgtt ataggagctg tagctttaaa taagctggca gctttttctt
      721 ttaattcctg agggaagtct ttaatagtga aattgatacc tactccaata atgatatctg
      781 tgactaagcc agtttctaca gaggtcattg cttcagtaag gattcctcca attttatgat
      841 tgtttagata gatatcattg acccatttta tgtcgacatc tattaaagtt aggttcttaa
      901 tggctttgta gacagctcca gctacaagta gtgtgtagga tggtaatttg tcatagggga
      961 gatttggttt aagatggagt gtcatataaa taccaccttg tggtgagtag aaggaacgtt
     1021 gaaaacggcc tcggcctgct gtttgatagg aagctagata gagggtattt gcttcatggc
     1081 ctaaatcaat tgcttctttt gcatctagtt gtgttgattt tgtttcgggt ttaaagctga
     1141 ctttaattgg aagattttct tctagaatct ctggaagaat aaggtcacca ttcatcagtt
     1201 tatatcctct atttttgata ctatcaattt caatgccttc ttgttctagt cgcttgatgg
     1261 ctttccaaat tgctgttcgg cttagggata gtttttctgc gattttttct ccgctgatat
     1321 agtcggtttc tttagatagg atttggtaga cagcttggta ggatttcata atgttgcctt
     1381 tcttactagt tggtattgag agtattcttt tcttgtatga cttggagtct gattaaagta
     1441 ttgtttataa gctttcgaaa aatggagtgg atctgaaaaa cctaccgagt atgcaattac
     1501 cttgatggac tcttgggtat tttcgagaag ttgtctagct cggtgcattc gaacgtagag
     1561 taggtattct ttgggtgata aggtattaaa ttctttgaat acgcttgata agtagcttct
     1621 gtgaacggat agttcttttg ctaaatcttg aattgtaagt gattgaggat agtggctatc
     1681 aattaatcgt ttgcattcaa gatagagttg gtgggttgat gaaatattct tttttttctg
     1741 attgggagca atagttccca gatgaaacat cagttcatga agttgtccca tgatatggag
     1801 ttgagctaat tcacttgatt ttgtaatctg agcgaagcgg acaatgtctg agatgagttt
     1861 tgcagtagtc tgggtatgac aagtttcaga ttggatgaga taggattgat cagaaatttg
     1921 ggaaagagca aaataatcag gggctttccc tccagtgatt cctaaccagt agtaggccca
     1981 aggttcttta ctatctgctt gataaaaggt tagttcctct ggttttaata gaaagaaatc
     2041 tccttctttt aaatcaacaa ttttaccctt gtaatgaaat tttccttgtc ctttagtaat
     2101 gtaatgtaga acgtatgtat cacgaatggc tggaccaaaa gagtaattag gtgtgcattc
     2161 ctcatatcca taaaagctta gggcaaggtc gattgttcca gtctggtatt ctgaaaaaac
     2221 taacatgtgc tacctcctac ctaacatttt accatattct tgagacattt ttctattttg
     2281 gaaagcgatt tcaggtgata aaatataatc aataaagtga tgaggtgaag taaatgggag
     2341 ttaggataga gaataatcta ttttatgttg agagtaaaaa tctaagtttg attattgaaa
     2401 atcgaaatgg ctacttactt ttgaaacatt taggaaagac tattaagaac tataaaggtt
     2461 ccaatagtgt ttatgaacga gaccatgcct tttcaggaaa tccaacggct actaatcgaa
     2521 cctttagttt agatactcag cgacagattt ttggacaaca tggcttagga gattttagga
     2581 aaccaaccat acaggttcag catagtgtaa ctgaagtaac agactttcga tttgtagaag
     2641 caaagatttt aaaaggtcag aatggtccac agggcttacc ttctccacat agcatggacg
     2701 atacagagac tcttgtctta atgttagaag attctaaggc tcaacttagt ctgactttgt
     2761 attatactac ttttaataat gatgcgacta ttgctagcta cagtaaatta gataataata
     2821 gtaatcagga agttgtcatc cataaagatt tttcttttat ggctgatttt ccagctgcag
     2881 attacgaaat agtaactctg cagggtgctt atgctcgtga aaagactgtt agacgtcaac
     2941 aggtagaaca aggaatcttt tcgattagtt caaaccgagg tgcttctggt catgctcaaa
     3001 caccagctct tctactatgc gaacaaggag tcacagagga tgctgggaat gtgtttgcta
     3061 ttcaactaat gtatagtggc aactttgaag cttttgttca aaaaaatcaa ttgaatgaag
     3121 ttcgggtggc tattggcatt aatccagaaa acttttcttg gaagttagct cctgaggaat
     3181 actttgaaac accggtagct ttagtgactc attcagatca gggattaact ggtattagtc
     3241 atgaaagtca gaattttgta ctgaagcaca ttatgctaag tgaattttct aaaaaagaac
     3301 gtccaattct aatcaataac tgggaagcta cttactttga ctttcagaga gaaaaactgt
     3361 tagagttagc agatgaagct aagaaagttg gcattgaact ttttgtatta gatgatggtt
     3421 ggtttggcaa tcgttttgat gataatcgtg ctttaggtga ttgggttgtt aatgaggaaa
     3481 aactgggtgg aagtctagaa agtctgattt cagctatcca tgaaagaggt ttgcagtttg
     3541 gactttggtt agaacccgaa atgatttctg tagatagtga tttgtatcgt caacatcctg
     3601 actgggctat tcaggttcct ggctatgagc atacttattc tcggaatcaa ttagtactta
     3661 atcttgccaa tcctcaggta gtagaatact tgaaaagtgt cttagatcaa ctcctatttt
     3721 atcatgatat tgattacatt aaatgggata tgaaccgcaa tatcactaag ctagggaatg
     3781 gattaactta tctagagaca cagatgcaat ctcatcagta catgctgggg ctttatgaac
     3841 tcgtttctta tctgacagag aagcacagcc atattctctt tgagtcctgc tctggtggtg
     3901 gtggacgaaa tgatcttggt atgatgcgct atttcccaca agtctgggct agtgataata
     3961 ctgatgccat tgcacgttta ccaattcaat acggttcatc ctatctctat ccaaccattt
     4021 ctatgggggc tcatgtgtca gcagtaccga atcatcagat gggacgaatg acaccattag
     4081 aaacacgtgg ccttgtagca atgatgggaa atttgggcta tgaacttgat ttgacaaatt
     4141 tatcagatga agagaaagct acgattgcta atcaggtgaa cttgtataaa gaattacgac
     4201 cagtagttca gttaggacag cagtatagac taattaatcc tgatactgta tccaatgaag
     4261 cagctgtaca atttaattac ggaaatcaaa cgattgtaac ctacgttcgc gttttatctg
     4321 ttgtagagac catggaaaca actttaaaat taaaagattt ggatgaagag ggactatata
     4381 aattacagga aaatggcgaa gtttactcag gtgcagaact aatgtatgcg ggcttaactg
     4441 ttatcttatc ccaaggagat tttttgagta gacagtatat ttttagaaaa ctatgatatg
     4501 tactgacccc aaaagttaga tttattctgt ctaacttttg gggtgcagtt caataagggt
     4561 gtataaattt ataaaggagg ctttctaatg gaatggtata aaaaaatcgg acttcttgca
     4621 actacaggtt tagctttgtt tgggctcggc gcttgctcca actatggtaa atctgcggat
     4681 ggcacagtga ccatcgagta tttcaaccag aaaaaagaaa tgaccaaaac cttggaagaa
     4741 atcactcgtg attttgagaa ggaaaaccct aagatcaagg tcaaagtcgt caatgtacca
     4801 aatgctggtg aagtattgaa gacacgcgtt ctcgcaggag atgtgcctga tgtggtcaat
     4861 atttacccac agtccatcga actgcaagaa tgggcaaaag caggtgtttt tgaagatttg
     4921 agcaacaaag actacctgaa acgcgtgaaa aatggctacg ctgaaaaata tgctgtaaac
     4981 gaaaaagttt acaacgttcc ttttacagct aatgcttatg gaatttacta caacaaagat
     5041 aaattcgaag aactgggctt gaaggttcct gaaacctggg atgaatttga acagttagtc
     5101 aaagatatcg ttgctaaagg acaaacacca tttggaattg caggtgcaga tgcttggaca
     5161 ctcaatggtt acaatcaatt agcctttgcg acagcaacag gtggaggaaa agaagcaaat
     5221 caataccttc gttattctca accaaatgcc attaaattgt cggatccgat tatgaaagat
     5281 gatatcaagg tcatggacat ccttcgcatc aatggctcta agcaaaagaa ctgggaaggt
     5341 gctggctata ccgatgttat cggagccttc gcacgtgggg atgtcctcat gacaccaaat
     5401 gggtcttggg cgatcacagc gattaatgaa caaaaaccga actttaagat tgggaccttc
     5461 atgattccag gaaaagaaaa aggacaaagc ttaaccgttg gtgcgggaga cttggcatgg
     5521 tctatctcag ccaccaccaa acatccaaaa gaagccaatg cctttgtgga atatatgacc
     5581 cgtccagaag tcatgcaaaa atactacgat gtggacggat ctccaacagc gatcgaaggg
     5641 gtcaaacaag caggagaaga ttcaccgctt gctggtatga ccgaatatgc ctttacggat
     5701 cgtcacttgg tctggttgca acaatactgg accagtgaag cagacttcca taccttgacc
     5761 atgaactatg tcttgaccgg tgataaacaa ggcatggtca atgatttgaa tgccttcttt
     5821 aacccgatga aagcggatgt ggattaggag tagagagact atgaaaaaag tattacaaaa
     5881 atattgggca tgggcttttg tggtcatccc cctcttgtta caagcaattt tcttctatgt
     5941 gccgatgttt caaggagcct tttacagttt taccaactgg acaggattga cttataacta
     6001 caaatttgtt ggcttaaaca actttaagct cctcttcatg gatccaaaat tcatgaatgc
     6061 gattggcttt accgcaatca ttgcgattgc catggtggtt ggtgagattg cactcgggat
     6121 cttcattgcg cgtgtcttga attctaaaat caaaggccaa accttcttcc gtgcttggtt
     6181 cttcttccca gctgttttat ctggtttgac agtggctttg atcttcaagc aagtcttcaa
     6241 ctacggtctt ccagcgattg gaaatgccct tcatattgaa tttttccaaa ccagtctttt
     6301 agggactaag tggggagcaa tctttgcggc tgtctttgtc cttctttggc aaggggtggc
     6361 tatgcccatc atcatcttcc tagctggttt gcaatctatt ccaactgaga ttacagaggc
     6421 agcaaggatt gatggtgcga ctagcaagca agttttctgg aacattgaat tgccttactt
     6481 gctaccaagt gtctctatgg tctttatcct agccctaaaa ggtgggctga ctgcctttga
     6541 ccaagtcttt gccatgaccg gtggtggtcc aaacaatgcc acaacctcac ttgggctctt
     6601 ggtttataac tatgccttta aaaacaacca attcggttat gccaatgcca ttgccgtaat
     6661 cttgttcttc ttaattgtag tgatttcgat catccaattg agagtatcta agaaatttga
     6721 aatttaagag gagaagcatg atgaaacaag atgaaagaaa agccctgatt ggcaaataca
     6781 ttctattgat tctaggatcg gttctgattt tagtgccgct ccttgctacc ctctttagtt
     6841 ccttcaaacc cactaaggat attgtagata atttctttgg ctttccaacc aacttcacat
     6901 gggacaactt tagccgtctc ttagctgatg ggattggagg ctattattgg aactctgtcg
     6961 tcatcactgt cttgtcttta cttgcagtaa tgatctttat ccctatggca gcctactcca
     7021 tcgctcgcaa tatgagtaaa agaaaagcct ttaccatcat gtataccctc ttaatcctcg
     7081 gaatcttcgt acctttccaa gtcatcatga ttccgattac ggttatgatg agtaaactcg
     7141 gtttggctaa tacctttggt ttgatcttgc tctacttgac ctatgcgatt ccacagaccc
     7201 tctttctcta tgttggctat atcaaaatct cgattccaga aagtctggat gaagcagcag
     7261 agatcgatgg ggctaatcaa tttacaacct atttccgcat catcttccca atgatgaaac
     7321 cgatgcatgc gacaaccatg atcatcaatg ccctttggtt ctggaatgac ttcatgttgc
     7381 cactccttgt cttgaaccgg gattccaaaa tgtggactct gcctttgttc caatacaact
     7441 acgcaggcca atatttcaac gactacggac caagctttgc ctcttacgtg gtcggcatta
     7501 tcagtatcac cattgtctat ctcttcttcc aacgccatat catttcagga atgagcaacg
     7561 gggcagtgaa gtaatactca atgaaaatca aagagcaaac taggaagcta gccgcaggtt
     7621 gctcaaaaca ctgttttgag gttgtggatg aaactgacga agtcagtaac catacctacg
     7681 gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga gtataagaag agctcatgga
     7741 atctatagtc tttgacacag aggaagagtt tagcttgttg ataattctat gcagaaaaca
     7801 agaaagtagt actttgttta tcacagtcta tattagtacg agtttgatga taaatagaga
     7861 tttaaaatga attttattta tgaagccaga tcatatgaga cttggcttca attagaaaaa
     7921 ggagagtaat gatgccaatt caaaataaaa ccatgttgat tacctattct gatagccttg
     7981 gaaataatct taaagactta tatgataatt tggaagagca ttttggagat gctattggag
     8041 gagttcacct tttaccattt ttcccatcaa caggtgatcg tggatttgcg ccagttgact
     8101 acgacgaagt ggactcagct tttggtgatt gggaggatgt taagcattta ggtgagaaat
     8161 attatcttat gtttgatttt atgattaatc atatttctcg tcaatccaag tattataagg
     8221 actatcaaga aaaacatgaa gccagtgaat ttaaagctct ctttttaaac tgggataagt
     8281 tttggccaga aaaccgtccg acacagtctg atgtagattt aatttacaag cgtaaggatc
     8341 gtgcaccaaa gcaagagatt gtgtttgaag atggttcagt ggaacatttg tggaatacct
     8401 ttggtgagga gcagattgat cttgatgtga ccaaagaagt aactatggaa tttatccgta
     8461 agaccattca gcacttggca agtaatgggt gtgatttgat tcgtctagat gcctttgctt
     8521 atgcagtgaa gaaattggat actaatgatt tctttgtgga accagatatt tgggatttat
     8581 tggacaaagt tcgagatatc gctgctgagt atgggacaga gcttttacct gagattcatg
     8641 aacactattc gattcagttt aaaatagcag accatgatta ctatgtttat gattttgctc
     8701 ttccaatggt gacactttat actctttaca gttccagaac agagcgtttg gctaagtggt
     8761 taaagatgag cccgatgaag caatttacga cgctagatac ccatgatggg attggagtag
     8821 tagatgtcaa ggatatcctg accgatgagg agattgacta tgcttcaaat gaactctata
     8881 aggttggagc caatgtcaaa cgtaagtact ctagtgccga gtataacaac ttagatatct
     8941 accaaatcaa ttcaacctac tattcagcgc ttggagatga tgatgtcaag tattttctcg
     9001 ctcgtctaat tcaagctttt gccccaggta ttcctcaggt ttactatgtg ggtctattag
     9061 caggcaagaa tgacttgaaa ttattagaag aaactaaaga aggtcgaaat attaatcgtc
     9121 attactatag caacgaggaa atagcaaaag aagtgcaacg acctgttgtg aaggcccttc
     9181 tcaatctatt ttctttccgt aaccgttcag aagcctttga tctagaaggg actactgaga
     9241 tagagacacc aacagctcac agcattgtaa tcaaacgtca aaataaagat aagtccgtaa
     9301 cagcagtagc agaaattgat ttgcaaaatc agacttatcg ggtaattgag aatggagttg
     9361 aagtaacatt ttgaagcctt gatatggtgg ataaaatagg gtttttattt tggaaaacgt
     9421 ttcctttgtt ttcaaattgc taaaaaagtg gtacaatata ggacagctta ctattatctg
     9481 aatcagctga tttggagaga aaggattcat tttgaaatca ataggcttta ttgaaaagct
     9541 gaaggggttg tctagtaaag agctgatttt attgggaatt atcctaagta tctttttacc
     9601 cttttatctt tttgtagttg tactctgttt atatattatc agtttgattt ttacaggaga
     9661 catgaaaagt attcttcaga aaatggggga gcatccgatg ctgcttcttt ttcttagcta
     9721 tagtactgtt atatccattc ttgcacaaaa ttggatgggt cttgtggctt cagtaggaat
     9781 gtttctattt actattttct ttttgcacta tcagtcgatt ttatcccata aattctttcg
     9841 attgattttg cagttcgtct tgtttggtag tgtcttgtca gctgcttttg ccagtttaga
     9901 acatttccaa attgtgaaga aatttaacta tgcttttctt tcacccaata tgcaggtgtg
     9961 gcatcagaac cgggcagaag tgaccttctt taatcctaat tattatggaa ttatttgttg
    10021 tttctgtatt atgattgctt tctatctgtt tacaacgacc aagttgaatt ggttgaaagt
    10081 attctgtgtg attgcaggct ttgttaatct ctttggtttg aactttactc aaaatcgaac
    10141 tgcctttcct gctattatcg ctggagcaat tatctatctc tttacgacta ttaaaaactg
    10201 gaaggccttt tggcttagta ttggggtctt cgcgattggt ttgagtttcc tcttttctag
    10261 tgatttggga gttcgaatgg gtactttaga ctcttctatg gaagaacgca tttctatctg
    10321 ggatgctggg atggccttgt ttaagcaaaa tcctttttgg ggtgaagggc cattgaccta
    10381 tatgcactct tatcctcgga tacatgctcc ttatcatgaa catgcccaca gtctttatat
    10441 tgatacgatt ctgagttacg gaattgtggg taccatttta ttagttttgt cttctgttgc
    10501 tcctgttcgc ttgatgatgg atatgagtca ggagtcgggg aaacgtccga ttatcggcct
    10561 ttatctatct ttccttacag tggttgctgt gcacggaatt tttgacttgg ctctcttctg
    10621 gattcagtca ggctttattt tcttgctagt tatgtgcagt attccattgg agcatcgaat
    10681 gttggtatcg gacatgacgg attaagtttt ataagtttga aatcttctac cttgggtagg
    10741 agattttttt atacgatggg catgtcgtgc atctgaggtg taagtcctct gtagggatcc
    10801 actaccggtg aatacaatag cgctccccaa gcctgactat cgtgaggtag cggattaaaa
    10861 tggtctgggg atagatcgtt ttaagtctga cgcaggaaat aagaattgtc agagaaagca
    10921 atagtgaaat cgtaggctat gaatagaaac gtgatagcga ggagcatata gtggataagg
    10981 tagcgagaaa ttttaaagta taaaagatag tcttaatcta tatatgtaaa tcacaaaagt
    11041 aattgaattc ggaataaggt tggtgtgaaa agacatagta aactgaatct tgaatactag
    11101 aatgatactt ctacaatatt gttataattt aatttgaatt ccaaaatcac attgtttcgt
    11161 ccgtatttca ttttactgta tgtcttccta aactccaaag tttctgcgtc aaatttccta
    11221 ttttcactgt agtctttgac acttcgaacg acaatttgaa tcatatattc aaaaaaaaat
    11281 gaaaaatttg tgccaacaag cctaaatatt ctgaaaattt gtttgatttt taatggataa
    11341 tgtgatataa tggttgtcaa tctataattc acataaacag aggagtagaa aatgaaaaaa
    11401 aatcgtgtat ttgctacagc aggtcttgtt ttattagcag caggtgtact tgcagcatgc
    11461 agttcttcaa aatcatctga ttcatcagcc cctaaagctt atggctatgt ttatacagca
    11521 gacccagaaa ccttggacta cctgatttca agtaaaaata gtacaacagt agtgacttca
    11581 aatgggattg atggtttatt cactaacgat aattacggta atcttgctcc tgcagttgca
    11641 gaggattggg aagtctctaa ggatggtttg acctacactt ataagattcg taaaggggtt
    11701 aaatggttta cctctgatgg agaagaatat gcagaggtga cggctaaaga tttcgtgaac
    11761 ggtttaaaac acgcagcaga taaaaaatca gaagctatgt atttagctga aaattcggtt
    11821 aaaggcttgg cagattatct atcaggaact tcaacagatt tttcaacagt tggtgtcaag
    11881 gcggttgatg attatacgtt acaatacact ttgaaccagc ctgaaccgtt ctggaactct
    11941 aagttgacct attctatttt ctggcctctg aatgaagaat tcgaaacatc aaaaggaagc
    12001 gattttgcta aaccaacaga tccgacatcc ttgctttata atggtccatt cttgttgaaa
    12061 gggttgactg caaaatcttc tgtagagttt gtaaaaaatg agcaatattg ggataaagaa
    12121 aatgtccacc tagatactat caatctagct tactatgatg gatcagatca ggagtcgcta
    12181 gagcgtaact tcactagtgg agcttatagt tatgcccgtc tttaccctac cagctccaac
    12241 tattctaagg ttgcagaaga atacaaggac aatatctatt acacacaatc aggctctggg
    12301 attgctggtc tgggtgtgaa tattgatcgc caaagttaca actatacttc taaaactaca
    12361 gattcagaga aagtagctac taagaaggca ttgcttaaca aagatttccg tcaagccttg
    12421 aattttgctc ttgatcgctc agcttactca gctcaaatca atggtaaaga tggagcagct
    12481 ttagcagttc gtaatttatt tgtaaaacca gactttgttt cagctggtga gaagaccttt
    12541 ggtgatttag tcgctgctca acttcctgct tatggtgatg agtggaaagg tgtgaattta
    12601 gctgatgggc aggatggttt attcaatgct gacaaggcca aggcagagtt tgcgaaagct
    12661 aagaaagctt tagaagcaga cggcgttcag tttcctattc atctggacgt tccagtagac
    12721 caagcatcaa aaaactacat atctcgtatt cagtccttta aacaatctgt agaaacagtt
    12781 cttggtgttg aaaatgtcgt tgttgatatt caacaaatga caagtgatga attccttaat
    12841 attacttact atgctgccaa tgcttcatct gaggattggg atgtatcagg aggagtttca
    12901 tgggggccag actatcaaga cccatctact tacctggata ttttaaaaac aactagcagt
    12961 gaaactacaa aaacatattt aggatttgat aatccaaata gcccttcagt agttgaagtt
    13021 ggtttgaaag aatacgataa attagttgat gaagctgcca gagagacaag cgacttgaat
    13081 gtccgttatg aaaaatatgc agcggctcaa gcatggttga cagatagttc actctttatt
    13141 cctgctatgg cttcttctgg tgcagcacca gtgctttcac gaattgttcc atttactgga
    13201 gcttctgcgc aaacaggctc taaggggtca gatgtttact tcaaatattt gaaattacaa
    13261 gataaagtgg tgactaagga agagtatgaa aaagctcgtg aaaaatggtt gaaagaaaaa
    13321 gctgaatcaa atgagaaagc tcaaaaagaa ttggcaagtc atgtgaagta aataatttct
    13381 aatagaactt tctctccatg aggagaaggt tcttttggga tttttaaagg aaataatatg
    13441 aaaaaatata tttttatgcg tgttttgcgg tcattggttt cgattttctt agtaacgact
    13501 ttgacctaca cgattatcta taccttggtt cctcgaaaat tgattttcaa gcaggatcct
    13561 aactataata aaattgcgac aacggctgat aaacgtgata actatgaaaa tactgtgttt
    13621 gagcgtatgg gctacattga gtattacgat actaaagagt tgcaagaaaa ggcaagtagc
    13681 atggattctt ctgtaacagt agaagcaaat gcgaccaata aagctattta tgaaaagtac
    13741 atcaatcaat taggtcatgg ttggactttg ggagaattta ctgaaagtgg tcaattctat
    13801 gctactcgtg aaattccaat ttttgaacgt gtttttcact tctatgctaa cttgattgac
    13861 attgaccata caaataaaat ccaagaccct gaaaatccag acttgaaacg ctaccttcgt
    13921 tttgaaaatg atccagctat cggatggtca ttggtcggtt caggaactaa acataaatat
    13981 ctcttgtact ttaacagtca gttcccattt gttcatcaaa actttgtgaa cttgaattta
    14041 ggtgactctt acccaaccta tgctaataca ccagttcttc aggttattac tcaaggtcaa
    14101 ggacaaacca aaactgccca agttcagttc ccaacaggta agaaaacgtc ttctgtaaat
    14161 atttactcaa gaacctacaa gtcacctagt caggctgact ctcgtgaagt agctagctat
    14221 gggaaagatg atccttatac agcgactgaa agtaattacc aatatccatc tatgattgtc
    14281 agctctgcta ttactggttt gattggtttg gttcttgcct atgctcttgc cgtgccactt
    14341 ggttcagcca tggctcgttt caagaacact tggattgata gcctctcaac aggggctttg
    14401 accttcttgc ttgctcttcc aacgattgcc ttggtttaca tcgttcgatt gattggatca
    14461 tctattgccc ttccagattc attccctatc ttgggagctg gagattggcg ttcttacgtt
    14521 ttaccagcag tcatccttgg tttgttgggt gctcctggta cagccatttg gattcgtcgt
    14581 tacatgattg acttgcaatc tcaagacttt gttcgtttcg ctcgtgcaaa aggtttgtct
    14641 gaaaaagaaa tttcaaacaa acacatcttt aaaaatgcca tggttccgct ggtttcagga
    14701 attcctggtg ccattattgg ggttatcggt ggtgcaaccc ttactgaaac agtcttcgcc
    14761 ttcccaggta tgggtaaaat gttgattgac tctgtaaaag catctaataa ctctatggtc
    14821 gttggtcttg tcttcatctt tacatgtatt tctatcttct cacgtctttt gggagatatt
    14881 tggatgacta ttattgaccc acgtattaaa ttgactgaga aaggaggcaa ataatgtcta
    14941 caatcgataa agaaaaattt cagtttgtaa aacgtgacga ttttgcctct gaaactattg
    15001 atgcgccagc atattcttac tggaaatcag tgtttaaaca atttatgaag aaaaaatcaa
    15061 ctgtagtcat gttgggaatc ttggtagcca tcattttgat aagtttcatc tacccaatgt
    15121 tttctaagtt tgatttcaat gatgtcagca aggtaaacga ctttagtgtt cgttatatca
    15181 agccaaatgc ggagcattgg ttcggtactg acagtaacgg taaatcgctc tttgacggtg
    15241 tctggttcgg agctcgtaac tccatcctca tttctgtgat tgcgacagtg attaacttgg
    15301 ttatcggtgt ttttgtcggt ggtatttggg gtatttcaaa atcagttgac cgtgtcatga
    15361 tggaagttta caacgtcatc tcaaacatcc cacctctttt gattgttatt gtcttgactt
    15421 actcaatcgg agctggattc tggaatctga tttttgccat gagcgtaaca acatggattg
    15481 gtattgcctt catgatccgt gtgcaaatct tgcgctatcg tgacttggaa tacaacttgg
    15541 cgtcacgtac tttgggaaca ccaaccttga agattgttgc caaaaatatc atgcctcaat
    15601 tggtatctgt tattgtgaca accatgactc aaatgcttcc aagctttatc tcatacgaag
    15661 ccttcttgtc tttcttcggt cttggattac cgattacagt gccaagtttg ggtcgtttga
    15721 tttcggatta ttcacaaaac gtaacaacca atgcttactt gttctggatt ccattgacaa
    15781 cccttgtctt ggtatccttg tcccttttcg tagttggtca aaacttagcg gatgctagtg
    15841 atccacgtac acatagatag gagtagaaat gacaaaagaa aaaaatgtaa ttttgactgc
    15901 tcgcgatatt gtcgtggaat ttgacgttcg tgacaaagta ttgacagcca ttcgcggcgt
    15961 ttcccttgaa ctagtcgaag gagaagtatt agccttggta ggtgagtcag gatcaggtaa
    16021 atctgttttg acaaagacct tcacaggtat gctcgaagaa aatggtcgca ttgcccaagg
    16081 tagtattgac taccgtggtc aggacttgac agctttatct tctcacaagg attgggaaca
    16141 aattcgtggt gctaagattg cgactatctt ccaggaccca atgactagtt tggaccccat
    16201 taaaacaatt ggtagtcaga ttacagaagt tattgtaaaa caccaaggaa aaacagctaa
    16261 agaagcgaaa gaattggcca ttgactacat gaataaggtt ggcattccag acgcagatag
    16321 acgttttaat gaatacccat tccaatattc tggaggaatg cgtcaacgta tcgttattgc
    16381 gattgccctt gcctgccgac ctgatgtctt gatctgtgat gagccaacaa ctgccttgga
    16441 tgtaactatt caagctcaga ttattgattt gctaaaatct ttacaaaacg agtatcattt
    16501 cacaacaatc tttattaccc acgaccttgg tgtggtggca agtattgcgg ataaggtagc
    16561 ggttatgtat gcaggagaaa tcgttgagta tggaacggtt gaggaagtct tctatgaccc
    16621 tcgccatcca tatacatgga gtctcttgtc tagcttgcct cagcttgctg atgataaagg
    16681 ggatctttac tcaatcccag gaacacctcc gtcactttat actgacctga aaggggatgc
    16741 ttttgccttg cgttctgact acgcaatgca gattgacttc gaacaaaaag ctcctcaatt
    16801 ctcagtatca gagacacatt gggctaaaac ttggcttctt catgaggatg ctccaaaagt
    16861 agaaaaacca gctgtgattg caaatctcca tgataagatc cgtgaaaaaa tgggatttgc
    16921 ccatctggct gactaggagg aaggaaatgt ctgaaaaatt agtagaaatc aaagatttag
    16981 aaatttcctt cggtgaagga agtaagaagt ttgtcgcggt taaaaatgct aacttcttta
    17041 tcaacaaggg agaaactttc tcgcttgtag gtgagtccgg tagtgggaaa acaactattg
    17101 gtcgtgctat catcggtcta aatgatacaa gtaatggaga tatcattttt gatggtcaaa
    17161 agattaatgg taagaaatcg cgtgaacaag ctgcggaatt gattcgtcga atccagatga
    17221 ttttccaaga ccctgccgca agtttgaatg aacgtgcgac tgttgattat attatttctg
    17281 aaggtcttta caatcaccgt ttatttaagg atgaagaaga acgtaaagag aaagttcaaa
    17341 gtattatccg tgaagtaggt cttcttgctg agcacttgac tcgttaccct catgaattct
    17401 caggcggtca acgtcaacgt atcggtattg cccgtgcctt ggtcatgcaa ccagactttg
    17461 ttattgcaga tgagccaatt tcagccttgg acgtttctgt acgtgcccaa gtcttgaact
    17521 tgctcaaaaa attccaaaaa gagctcggct tgacctatct cttcatcgct catgacttgt
    17581 cggttgttcg ctttatttca gatcgtatcg cagttattta caagggtgtt attgtagagg
    17641 ttgcagaaac agaagaattg tttaacaatc caattcaccc atatactcaa gccttgcttt
    17701 cagcagtacc aatcccagat ccaatcttgg aacgtaagaa ggtcttgaag gtttacgacc
    17761 caagtcaaca cgactatgag actgataagc catctatggt agaaatccgt ccaggtcact
    17821 atgtttgggc gaaccaagcc gaattggcac gttatcaaaa aggactaaac taataatggt
    17881 tttataattt ccatgtcaat ttttatggga attataaaac tttttttgtt ggactgattt
    17941 gaaaaacttt gaaagcttcc tgaaagaatt ttcgaaaaat tttaaaaaat tttgaaatat
    18001 tattgacagg tgatgaaaaa ggtggtagga taggaaggat caaaaaagaa agcagaaaaa
    18061 gaaatgaata agagacaagc cgtaactatg aatcaaaact tttactttag ctactttaga
    18121 tagtgtttgt agacatgtca ccatggatgc aaacagttca agcaatttgt ttgtatctat
    18181 gtggctaaga tttttgattg tggtccatat agatgaatat ctaaatggac tagctaagtt
    18241 gtaacttgtt aggttatttc aagtacccgt ttagatagta tctaggcggt tttttgtttt
    18301 atcttttctg agaaggagtt tcattatgaa agttgttcga aaatcactag ccccctcttg
    18361 gtagtgggga tcctcttgac ttctctgatc agtttgcatc agttgaaggc agataagaaa
    18421 agagatgtct ttcgtatcgg tatttcgcag tttattaccc accagtcctt agacgctact
    18481 agagaaggat ttgtggatga gctggccaaa caaggctatg ttgaggggga aaatattgag
    18541 attgatttgc aaaatgcaca gggagaacaa agaaatctaa aaacgatttc ccagcaacta
    18601 gcagaatcca gcgatgtcgt tctagccatc gcaaggcctt ctgctcagag cttggccaat
    18661 acgacgcaaa cgccaccagt tatcttttca gctgtaacag acccagtcag tgccaagttg
    18721 gttgagtcaa gagaacatcc tgggggcaat gtaactggga caagcgatca gtcatcagat
    18781 gccatttcaa cccaaatcaa tttgataaag aaagtgttgc caaaggctaa aacgattgga
    18841 atcctctata ctcagagcga gcccaattcg gttgtttaaa atgatgaagc taagcgactt
    18901 ctgaaagaaa aaggctttac cgttgttgaa aaaacaatct tggacagtaa taacgtcaag
    18961 gcggcagcag agagtttgat ggcagaggtg gatatggttt ttgtcccaac tgataatatc
    19021 atttcgtcaa ccatggaaac agttaagcag gtttctatta aacacaaggt tccagtattc
    19081 ggtggttcaa cagaaatgat tgctgttggt gacttgtata actacggaac caattatgaa
    19141 gaattgggaa gacagacagc tcgcatgctg attcgtgttt taaaaggtga gaaaccagaa
    19201 aatatagcag ttgagttgcc tgaaaaactg gaattgcata ccaatcaaga aatggcagat
    19261 gcattgggaa ttgatattag taagttagaa ggcaaggaat aaggaggatt aagatgaatt
    19321 ttgtgttatc tagtttatca gaaggtttgt tgtggtcgat tgtggcgatt ggggtctact
    19381 tgactttccg tattttggat attgcggata taactgctga gggagccttt cctctggggg
    19441 cagcagtcgt tgtatcacag atacaggcag gggcaaatcc ttggcttgcg actttacttg
    19501 ctttgctggc aggtatggta gcaggtcttg tatcaggaat gctccacacc aagatgaaaa
    19561 tcccagctct cttgacaggg attgtgacct tgacagggct ctattcaatc aatattaaaa
    19621 ttatgggcag tgtacccaat ctttccttgg gagattctgc aaccgtcttt aaacagttgg
    19681 cgagcttggg tctgacaaat gaaggagctg ttttctcact tagtttagtc tgtctcttac
    19741 ttgtttggtc ttgacccttt tgatgaaaac agagattggt ttggtcttgc gttcgactgg
    19801 ggataatatc ccgataagtg aggccaatgg agtcaatgta gacaccatga agattgttgg
    19861 ttacatgatt tcaaacggtt tgattgccct atgtggttcc ttgtttgccc aaaatgatgg
    19921 attttcagat gtgacttctg ggacaggaac cattgttgtt ggtttgagct cggaagtctt
    19981 gatacacgac ttgaccattg gaggccgctt attatccatc ggaatcggtg ctattgttta
    20041 ccgtttgatt attttaaata tctatgaaat tccaaatcta gatcaaaact tggtacgtct
    20101 ctttaatgca atcttgctcg ctttggtttt atttgcacca gaattgcaaa agagattaaa
    20161 gattcgtggt ctgaaattga gaaatgaata ggaggagaaa gttatggcaa gtttgttaac
    20221 acttgaaaat attcacaaga catttgaagc agggacggtc aatgagaacc atgtcctcaa
    20281 aggattagat ttagaggttg aagagggaga ttttatctat gtgattggtg gaaatggagc
    20341 aggaaaatcc actttgatga atatcttggc tggcaatcta tcggtggacg aaggggacct
    20401 tctactggca gggaaatcca ttaaaaatct gagtgtcaga aagagagcca aggatattgc
    20461 ccgtgttttt caatatccta agatgggaac agcttctcgt ttgacgattg aggagaatat
    20521 ggctattgcc ttgagacgtg ggcaaaagag agggcttggt tggggtgtga aggagaagga
    20581 tagaatccag ttccaagagg ccttgaagga gttgaatatt ggtcttgaaa accgcttaaa
    20641 agtagatact caatatctct caggaggaca aagacaggct ttgaccctag tcatggcagc
    20701 tctggtgaaa cccaaacttt tacttttgga tgaacatact gcggcacttg acccgaaaac
    20761 cagtcaaatg gtgatggact tgacgcaaaa gattgtggag caccatcagt ggacgacttt
    20821 gatgattacc catgatatga atcatgcgat tgagtacggc aatcgtctca ttatgctcta
    20881 tcaaggcaag atagtggtgg atgtcaaggg agaagagaaa aagcatctga cagttgaaga
    20941 ccttatgcat ctcttccaga aaaatagtgg ccaaagtctg gtcagtgatg aattagtttt
    21001 gggataaaga aaaaggctga gatctggtgt ctcagtcttt tatttcttgc gttttgcaaa
    21061 atctacaaat ctaaattttt ctaacttatg gcgactttcg gtaaactgaa attggcgtcc
    21121 gtcttggaga tagacttttg atttaatcga aacgacataa gggtctttgc caatgtccat
    21181 gagaatcttg tctcggtcgc ttgagtggtc aatggtgatt tccttctgag cataatcaat
    21241 aaggagtttg aggccatttt ctatataaga atagatagac tgctcagcaa tttggcgagt
    21301 gagatttgga attagttcca tatccagata gtctgtatcc agaacggata ccagatcatc
    21361 caccacacgc tggcggacca ccttccaaac catccgaaac tctgggaaac cggttatcag
    21421 tgaggatttt ttatcaataa taatcttgtc cagactgacc acgttggttt tagagcgcag
    21481 tccaagttct ttaactagtt cttggtagct ggttaggttg gatacaggga aattgacggt
    21541 ttcttctttg acgacttgag aaccttgccc tcttatcttt ttgatcaatc cttcctcttg
    21601 gaggagagac agggcctttc ggacggtatc acgactcact tgatattgct ccataaggtc
    21661 gtgctcgcta ggaaggaaat ctccgacagc gtaagtctcg ttttgaatgg tttcttggat
    21721 ttgcttaaat aattgttggt atttcttcat tttgcctgct taaataggtt tttagtctag
    21781 tttaatgaac acctgtatct attttaccat acaagtgcta gaaaatttac aaaaaaacac
    21841 cctttttata ccaaacaagt tgcagacaag tttggtatcg tttacaatat acttatcaaa
    21901 tcaaacttgc tttgacaagt ataaggagaa tcaaatggga aaatttgaac aagaagccaa
    21961 agatctgctt caggcaattg gaggcaaaga aaatgtgact gccgtaactc actgtgcgac
    22021 acggatgcgc tttgttttag gagatgataa gaaggctaat gttaaagcta tcgagtcaat
    22081 tccagctgtt aaaggaactt ttacaaatgc aggtcaattt caggtaatca ttggaaatga
    22141 cgtgcccatc ttttataatg attttacagc cgtttcaggt attgagggtg tttccaaaga
    22201 agcagccaag tctgcagcta agagtaatca aaacgtggtc caacgtgtta tgaccactct
    22261 ggcggagatt tttactccga ttattccagc cttgatagtc ggaggattga tcctcggttt
    22321 ccgtaatgtc ttggaaggtg tccattggtc gatgttggat ggcaagacca tcacagaatc
    22381 ctctcagttt tgggcaggtg tcaatcactt cctctggttg cctggtgaag ctatcttcca
    22441 gttcttacca gtagggatta cttggtctgt ttctcgtaag atgggaacca gccaaatttt
    22501 gggaattgtt ctcggaatct gtttggtatc gcctcagttg ctcaatgcct atgcggttgc
    22561 ttcaacgcca gcagctgata tcgcggcaaa ctgggtttgg aattttggct attttactgt
    22621 taatcgtatc ggttaccaag cccaagttat cccagccttg cttgcaggtt tgagtctgtc
    22681 ttatcttgaa atcttctggc gcaagcatat cccagaagtc atttctatga tttttgtacc
    22741 tttcttgtca ttgattccag ccttgatttt ggctcatact gttttgggac caatcggttg
    22801 gacaattgga caagggcttt catcagttgt cttggcaggt ttaactggtc cagttaaatg
    22861 gctcttcggt gcaatttttg gtgccctcta cgctccattt gtcatcacag gtctgcacca
    22921 tatgaccaat gccattgata cacaattgat tgcggatgct ggtggcactg ccctatggcc
    22981 aatgattgct ctttctaata ttgctcaagg ctcagccgtg tttgcctatt atttcatgca
    23041 tcgccatgat gagcgtgagg ctcaggtttc acttcctgca accatttcag cctatctcgg
    23101 tgttacagaa ccagctcttt ttggggttaa cgtaaaatat atttatccat ttgttgctgg
    23161 gatgactggt tcagcccttg caggcatgtt atccgttact tttaatgtaa ctgcggcttc
    23221 tattggtatc ggtggtttgc caggtattct ctctattcaa cctcaataca tgctgccatt
    23281 tgcaggaact atgctagttg cgattgttgt tccaatgctc ttgactttct tcttccgcaa
    23341 ggctggtctc tttacaaaaa cagagggcga tacgaacttg caggcagaat tcgttgctca
    23401 agaagaagca gaatttgtga accatgaacc agtagaactt acttcggtag aaattatcag
    23461 cccactaact ggccaagtga aagaattgag tcaagcgacg gatcctattt ttgcatcagg
    23521 tgtcatgggg caaggtctag tcattgaacc aagccaaggt gagttgacct ctccagttaa
    23581 tgggacagtg acggttcttt tccctaccaa gcatgccatc ggcattgtct ctgacgaggg
    23641 agttgaattg ctcatccaca tcggtatgga tacagtaggt cttgatggca aaggttttga
    23701 aagtcttgta gtccaaggag atcacgttac agttggtcag caactgattc gttttgatat
    23761 ggatgtcatt aaggctgcag gtctggtgac agaaactcct gttatcatca ccaaccaaga
    23821 tgcttataca gcgactattc ccggaactta tccgacaacg atccaagctg gagcatctct
    23881 catggtcgct acacgaatct aatactcttc gaaaatctct tcaaaccacg tcagctctat
    23941 ctgcaacctc aaaatagtgt tttgagcaac ctgtggctag cttcctagtt tgttctttga
    24001 ttttcattga gtataattga aatagcacaa atagggacgg aagactgctt cctccctttt
    24061 atcagaaaag gagaaacaga tgacacttga taaaggaaaa gtagtctatc aaatctatcc
    24121 aaaatcttac aaagacacca ctgaaaacgg tattggggat ttccgtggga ttatcggaaa
    24181 aattccctat ctagccaaac taggtgtgga tatggtctgg ctcaatccat tctatccaag
    24241 tcctcaacgg gataatggtt acgatatttc agattatatg gcagtggatc ctctttttgg
    24301 tgatatggct gattttgagg aaatggtgtg tatcggtaaa gagcacaaga ttgactttat
    24361 gctggacatg gtacttaatc attgttcgac agagcatgaa tggtttcaga aagccctagc
    24421 tggtgataag tattatcaag actttttctt catccaagac caaccaacag attggcagtc
    24481 taagtttggt ggttctgcat gggcgccttt cggggatact gggaaatact atcttcacct
    24541 atttgatgag acccaggctg accttaactg gcgcaatccc aatgtccgta aggagctttt
    24601 caaggttgtt aatttctggc gcgacaaggg tgtcaaaggt tttcgatttg atgtgatcaa
    24661 tttgattggt aaggacgagg tttcagtgga ctgtcctgaa aatgaaggga agccagctta
    24721 tacagacaaa cccatcgttc ataactattt gcgtatgatg aaccaagcca cttttggatc
    24781 tgacgatagc tttatgacag ttggggaaat gtcttctacc accatggaaa actgtgtcct
    24841 ctattcgtcg cctgatcgtc aggaattatc catgaccttt aattttcatc acctcaaggt
    24901 ggactataag gatggacaaa agtggacctt ggctcccttt gattttgaag agttgaagag
    24961 tctttaccat agttggggta aggaaatgag tgataaagac ggttggagtg ccctcttttg
    25021 gaacaatcac gatcaaccac gtgccttgaa ccgttttgtc gatattcaaa acttccgcaa
    25081 ggaaggagcc accatgctag cagccagcat tcacctgtca cgtgggacac cttatatcta
    25141 catgggtgag gaaatcggga tgattgaccc agactatgat tctatggctg attatgtgga
    25201 tgtcgaatcg cttaatgcct atcagatgct cttagaagaa ggaaagagtc agcaagaagc
    25261 cttccagatt attcaagcta agtcgcgtga taattcacgc attcccatgc agtgggatgc
    25321 ttcggaaaat gcaggatttt caacaggcac tccttggttg aaagctggta aatcctataa
    25381 atacatcaat gtagaaaatg aaatccaggg tccgattttt accttctatc aagacttgat
    25441 tcgactgcgt aaggaaatgc caatcatttc agaaggaagt tacaaaccag cctttgaaga
    25501 tagcaaacaa gtctacgctt ttgaacgcca gtttgaggat caaaagttac tagtgctcaa
    25561 taacttttat gctaaagaag tggaaatcga cttgccagca gtctaccaaa atggacagat
    25621 tttgatttca aactatgaag atgcagaagt gtctgagaaa attctactaa aaccctatca
    25681 aacactggct atttatgtaa attaaactta gcaaggagac ctctttttca gaaaagcagg
    25741 tctttttttg ctgtctattc catccttgaa agtgtagaac aaactggtca gggtggctag
    25801 tttgtggtat aatgaaaggg actcaaaaag aaacaggaga aaaatgatgg atttactttt
    25861 agcaattgta ttgattgtgc tagcttttct aggaggagct cttggaggaa tgtacttggt
    25921 tcgtaagcaa atcgaaaaag aatttgctga caacccacgt ttgaatgctg aagcagttcg
    25981 tactcttttg agtgcaaatg gtcaaaaacc aagcgaagct aaggtacaac aagtttacca
    26041 ccaaatcatc cgccaacaaa aggcagccct tgctaacaat aaaaagaaaa aataaataag
    26101 gaaaagtctg ggatgaaagt tccagacttc tcactatgtt ggttatggtt tagggatgag
    26161 actttttcct tgcattctat tgatatttga ttatgattaa gagagaggta gttgacattc
    26221 tatcaagctg tcggtcagtt cgttcagtac aaggaatcat aatgaacgat caatcagaaa
    26281 aaagactaga aagaagactg tatggataat cgaccaattg gttttttgga ttcgggtgtc
    26341 gggggcttga ccgttgtgcg cgagctcatg cgccagcttc cccatgaaga aatcgtctat
    26401 attggagatt cggcgcgggc gccctatggc ccccgtcctg ctgagcaaat tcgtgaatat
    26461 acttggcagc tggtcaactt tctcttgacc aaggatgtca aaatgattgt cattgcttgt
    26521 aacactgcga ctgcggtcgt ctgggaagaa atcaaggctc aactagatat tcctgtcttg
    26581 ggtgtaattt tgccaggagc ttcggcagcc atcaagtcca gtcaaggtgg gaaaatcgga
    26641 gtgattggaa cgcccatgac ggtacaatca gacatatacc gtcagaaaat ccatgatctg
    26701 gatcccgact tacaggtgga gagcttggcc tgtcccaagt ttgctccctt ggttgagtca
    26761 ggtgccctgt caaccagtgt taccaagaag gtggtctatg aaaccctgcg tcccttggtt
    26821 ggaaaggtgg atagcctgat tttgggctgt actcattatc cactccttcg ccctattatc
    26881 caaaatgtga tggggccaaa ggttcagctc atcgatagtg gggcagagtg cgtacgggat
    26941 atctcagtct tactcaatta ttttgaaatc aatcgtggtc gcgatgctgg accactccat
    27001 caccgttttt acacaacagc cagtagccaa agttttgcac aaattggtga agaatggctg
    27061 gaaaaagaga ttcatgtgga gcatgtagaa ttatgacaaa taaaatttat gaatataagg
    27121 atgaccagga ctggtatgtt gggtcttata gtatttttgg tggcgttaac agtttgagcg
    27181 actatcagac agattttcct ctgtttgaat tctccaaaat atttggagat gaagagtatg
    27241 gtttcccgct ttcagttact gttttacgct atggttctac ctaccgtttg ttctcctttg
    27301 tggtagatat gcttaatcaa gaaatgggac gaaacttgga agttattcaa cgtcatgggg
    27361 ccctgctctt ggttgaaaat gggcaactct tgtatgtaga attgcctaaa gaaggggtca
    27421 atgttcatga tttctttgag acaagcaagg tcagagaaac cttgttgatt gcgactcgta
    27481 acgaaggcaa aaccaaggaa ttccgagcta tctttgataa gttaggctac gatgtggaaa
    27541 atcttaatga ctaccctgac ctgcctgaag tagcagaaac aggtatgacc tttgaagaaa
    27601 atgcccgcct taaggcagaa accatttctc aattaacggg taagatggtt ttggcagatg
    27661 attctggtct caaagtcgat gtccttggtg gcttaccagg cgtctggtca gctcgtttcg
    27721 caggtgtggg agcaactgac cgtgaaaata atgccaaact cttgcacgaa ttggccatgg
    27781 tctttgaact caaggaccgc tcggctcagt tccacacaac cctagtcgta gccagcccaa
    27841 ataaggaaag tttagttgtt gaagcagact ggtcaggtta tattaacttt gaacctaagg
    27901 gtgaaaatgg ctttggctat gatcccctct tccttgtagg agagacaggt gagtcatcag
    27961 ctgaattaac cctggaagaa aaaaatagtc aatctcaccg tgccttagcc gttaagaaac
    28021 ttttggaggt atttccatca tggcaaagca aaccatcatt gtaatgagcg attcccatgg
    28081 cgatagcttg attgtggaag aagtccgtga tcgctatgtg ggcaaagtcg atgccgtttt
    28141 tcataacggc gattctgaac tacgtccgga ttctccactt tgggagggca tccgcgttgt
    28201 taaagggaac atggacttct acgccggcta cccagaacgt ctggtgactg agcttggttc
    28261 gaccaagatt atccaaactc atggtcactt gtttgacatc aatttcaact ttcaaaagtt
    28321 ggactactgg gctcaggagg aagaggccgc tatctgcctc tatggtcact tgcatgtgcc
    28381 aagtgcttgg atggaaggca agatcctctt tctaaatcca ggttctatca gccaaccacg
    28441 aggtaccatc agagaatgtc tctatgctcg tgtggagatt gatgatagtt acttcaaagt
    28501 ggactttttg acacgagatc acgaggtgta tccaggtttg tccaaggagt ttagccgatg
    28561 attgccaagg agtttgagac tttcttgttg gggcaggagg aaactttttt gacccctgct
    28621 aaaaatctag ctgtgttgat tgatacccac aatgcggatc atgcgaccct cttgcttagt
    28681 cagatgacct atacccgtgt tcccgttgtg acagatgaaa aacagtttgt tgggacgatt
    28741 ggactcagag atattatggc ttatcagatg gagcatgact tgagccaaga aatcatggcg
    28801 gatacggata tcgttcatat gacaaaaacg gacgtagcgg ttgtttcgcc tgatttcacc
    28861 attacggagg tcttgcacaa gctagtagat gagtccttct taccggttgt ggatacagag
    28921 ggtattttcc aagggattat tacgcgcaag tccatcctca aggccgttaa tgccctcttg
    28981 catgatttta gtaaggaata tgagattcga tgccaatgag agacagaatt tcagcctttt
    29041 tagaggaaaa gcagggcttg tctgtcaatt ccaagcagtc ctataagtat gatttggagc
    29101 aatttttaga catggtaggt gagcggattt ctgagaccag tctcaagatt taccaagccc
    29161 agctagccaa tctaaaaatc agcgcccaga agcgaaagat ttcggcctgt aaccaatttc
    29221 tatactttct ctatcaaaaa ggagaggtgg acagctttta ccgcttggaa ttagccaaac
    29281 aagctgaaaa gaagacggaa aagccagaga ttctatacct agactctttt tggcaggaaa
    29341 gcgaccatcc agagggccgc ttgctagcgc tcttaatcct agaaatgggg ctcttgccca
    29401 gtgagatttt agccatcaag gttgcggaca tcaatctgga ttttcaggtg ctgcgaatca
    29461 gcaaggcttc ccaacagagg attgtcacca ttcccacggc cttgctttca gaattggaac
    29521 ccttgatggg gcagacctat ctttttgaaa gaggagggaa accctattct cgtcagtggg
    29581 cctttcgtca gttagaatct tttgtcaagg agaaaggttt tccatcctta tcagctcaag
    29641 tcttacgtga acagtttatt ctaagacaaa tagaaaacaa ggtcgatttg tacgaaattg
    29701 caaaaaaatt aggattaaaa acagtcctga ccttagaaaa atatagataa tggatattaa
    29761 attaaaagat tttgaaggac ccctggactt actcttgcat ctggtttcta agtaccagat
    29821 ggatatctac gatgtgccca ttacggaagt catcgaacag tatctagcct atgtctcaac
    29881 cctgcaggcc atgcgtctgg aagtgacggg tgagtacatg gtcatggcta gtcagctcat
    29941 gctgattaag agtcgtaaac tccttccgaa ggtagcagaa gtgacagact tgggggatga
    30001 cctggagcag gacctcctct ctcaaatcga agaatatcgc aagttcaagc tcttgggtga
    30061 gcacttggaa gccaagcacc aagaacgggc ccagtattat tccaaagcgc cgacagagtt
    30121 gatttacgaa gatgcggagc ttgtgcatga caagacgacc attgacctct ttttggcttt
    30181 ttcaaatatc ctagccaaga aaaaagagga gtttgcacaa aatcacacga cgatcttgcg
    30241 ggatgagtat aagattgagg acatgatgat tatcgtgaaa gagtccttga ttggacgaga
    30301 tcaattgcgc ttgcaggatt tgttcaagga agcccagaat gtccaagagg tcatcaccct
    30361 ctttttggca accctagagt taatcaaaac ccaggagctg atcctcgtgc aagaggagag
    30421 ttttggagat atctatctca tggaaaagaa ggaagaaagt caagtgcctc aaagctagac
    30481 ttgatagaga ggaaagatga gtactttagc aaaaatagaa gcgctcttgt ttgtagcggg
    30541 tgaagatggg attcgggtcc gccagttagc tgaactcctc tctctaccac cgacaggcat
    30601 ccagcaaagt ttaggaaaat tagcccagaa gtatgaaaag gacccagatt ccagtttggc
    30661 tttgattgag acaagtggtg cttatagatt ggtgaccaag cctcaatttg cagagatttt
    30721 gaaggaatac tctaaggcgc ctatcaacca gagcttgtct cgggctgccc ttgagacctt
    30781 gtccattatt gcctacaaac agccgattac gcggatagaa attgatgcca tccgtggagt
    30841 taactcgagt ggagccttgg caaagttgca ggcttttgac ctgataaagg aagacgggaa
    30901 aaaggaagta ttggggcgcc ccaacctcta tgtgactacg gattatttcc tagattacat
    30961 ggggataaac catttagaag aattaccagt gattgatgag cttgagattc aagcccaaga
    31021 aagccaatta tttggtgaaa ggatagaaga agatgagaat caataagtat attgcccacg
    31081 caggtgtggc cagtaggaga aaagcagaag agctgattaa gcaaggcttg gtgacggtta
    31141 acggccaagt ggtgcgtgaa ctagcaacca ctatcaagtc aggcgacaag gtcgaagttg
    31201 aaggtcaacc tatctacaac gaagaaaagg tctactatct gcttaacaaa ccacgcggtg
    31261 tgatttccag tgtgacagat gataagggtc gcaagacggt tgtcgacctc ttgcccaatg
    31321 tcaaagagcg tatttaccct gtgggtcgtt tggactggga tacatcagga gtcttgattt
    31381 tgaccaatga tggggacttt acagacgaga tgattcaccc tcgtaatgag attgacaagg
    31441 tttatgtcgc gcgtgttaaa ggtgtggcca ataaggacaa tctccgcccc ttgacccgtg
    31501 gtcttgagat tgatggtaag aaaaccaagc cagctgttta tgaaattctc aaagtggacc
    31561 cagtcaaaaa tcgctctgtg gtgcagttga tcatccatga agggcgtaac catcaggtta
    31621 aaaagatgtt tgaagctgtt ggtctccaag tagataagtt gtctcggact cgttttggac
    31681 acctagactt gacaggactc cgtccaggag aatcccgtcg tcttaataaa aaagaaatca
    31741 gccaactaca caccatggct gtaactaaga aataatgaaa cgaattttaa tagcgcctgt
    31801 gcgcttttac caacgtttta tctcaccagt ctttccaccc tcttgtcgct ttgagctgac
    31861 ttgttccaac tacatgattc aggctattga aaaacatggt tttaaggggg tattgatggg
    31921 cttgtctcgg attttacgtt gtcatccctg gtcgaaaaca ggtaaggacc ccgttccaga
    31981 ccgcttttcc cttaaacgaa atcaagaagg ggaatgaggt ggggtaaata gatttcaaaa
    32041 tgataaaaac gcatcctatc aggtttgagt gaacttgata ggatgcgttt tagaatgtca
    32101 aaattttata ctcttcgaaa atctcttcaa accgcgtcag ctttcatctg caacctcaaa
    32161 acagtgtttt gagcaacctg cggctagttt tctagtttgc tctttgattt tcattgagta
    32221 ttaaattgag tttgaagtgg cttatttcaa agctttttgt atgtcttcaa tcatgagttt
    32281 tgttgattca agtccgcctc cgcttagata ccagaggtct ggtgttagtt ggataatctt
    32341 accattttta gcagcaggtg tttcagcgat aagggcattt tctaggacac cgtcgttgct
    32401 agagttgtcc ccaccgatgg caagggtacg gttgatgaca aagaggatgt cagggttgat
    32461 ttctttgaca ctttcaaagc tgacttcttg tccgtggcgt gagtcttcaa atgttgtatc
    32521 agttggtttg aatttcaagg tttggtacaa gaaagagaaa cgagatttgg caccaaaggc
    32581 tgccattttt ccttcattaa ggaggatcgc aagggctttt ttgtcagagc tttcattttt
    32641 agtagcgact tcttggatgc tcttgtctag cttggccaat tcttccttgg ctttctgtgt
    32701 accagtttcg ccgaaggcac ttgctaagga ttcgatatta gccttggtag aagtccagta
    32761 gtcgtccttg cttgcttgga agagaacggt tggggcgatt tctttgaatt tgtctacgaa
    32821 tttttgtgta cgtggtgaag cgataatcaa atcaggctca agggcggcga tagcttctaa
    32881 atcaggttct ttcatagaac caacattttt gacagttccc actaggtctt ttagataagt
    32941 cggaacagtt tttgtaggca ttccgacgat atttttttca aatcctaaag cgcgaatagt
    33001 atccgcagcg ccgaggtcaa aggtcacaat cttttcagga actttggaaa gtttgacctc
    33061 gtccagtgaa cttttaatgg ttacctctgt tggagcagag ctactggtct ctgtctgact
    33121 agtgcttgag tttgtactac atgcaccaag taggagcaag aagctggcca ctagggcagt
    33181 gaaataaagt ttaagggatg ttttcataat ttctcctttt taaaatgtga taacgattta
    33241 gggagtctct taatcttatt gactaagaga ctgaaggttc tctaacttga gcttttatgt
    33301 tactagctat agatacagat ctttttgtta ttgatatcag ctagcgtgat gggaatctca
    33361 taaagttgac tgagcaggtc agcctgcatg atttgatcgg ttcttccctt gctaaagacc
    33421 tggccgtcct tgaaggcgac aatttcatct gcatactgac tggccatgtt gatatcgtgg
    33481 aggacgatga taatggtctt gccgagttcc tccaccagtc gtcgaagaat ctgcatcatg
    33541 ctgacgcttt gcttgatatc gagattgttg agtggttcgt ccagcaagat aaagtccgta
    33601 tcctgggcca gtaccatagc gataaagacg cgctggagtt gcccccctga caggctattg
    33661 atgtagcggt cttttaagtt ggtcagttcc aaatagttca gagtttctcg gattttttcc
    33721 cagtcttctg atctaagtcg acctcggctg tagggaaaac gtccaaaact gaccagttct
    33781 tcaacagtca atttggcttg gtaattgatt ttctgtttta ggatggttag ttcttgggcc
    33841 agttcttgcg aattccagct ctcgatttca cgtcctttga tactgagaac tccctgatct
    33901 ttcttggtta gtctgctcat gatggagagg agagtcgatt ttccagcacc atttggacca
    33961 ataaaggctg tcagtttttg aggactgact tcaagcgaaa tgccttgcaa aatatcctgt
    34021 ttttgaatgg atttgtcaat gttttccagt ttcactgacg agccctccta tatagtaaga
    34081 taaagaataa gaagccaccc acactctcaa tgatcatact gatacgaatt tccagtgcaa
    34141 agactcgttc aatcaaggct tgccccaagg ttaagctaat aaatccaacc agaatggcca
    34201 ctataaagag taacttgtgc tgatagtctt tgacaatcag gtaggtgagg ttggccagca
    34261 taaagccgaa gaaggccata ggtcctacca aggcagtggc cgttgaggtc aaaagcacga
    34321 ttccccagag gagctctttc tgttcttttt taacatcgag tcccaatatc tgagccgttt
    34381 ctctttgcag gtgcaagaca tctagaacga ctgcttttcg aaagaaaaag attgtcaaag
    34441 cgaggatgat cagagaaccg atggctagga tggaagtgtt aagatgttga aaggaggcaa
    34501 aaagactatt ttgcagttta tcgtattcgt ttggatccat taggacttga aggaaggtgc
    34561 tgatatttcg aaagagactt ctgagcgcta gacagatcag caggatgaag accaggtctt
    34621 gcttcatcag tgtcttcaag taaccttgta aggcgagaaa gaagagggac tggacaagaa
    34681 gtaagactag gaattctaag ataggggatt tgcccagttg aagaaacttg ctttcaaaaa
    34741 ccagtagtag ggtttgtagt aggacgtaga aggattcaat tcccaaaata ctaggcgtca
    34801 ggaagcgatt ttccgtcagg gtttgaaaac taatggtcga aatcccagtc gcgatggcta
    34861 ccaagagata aacgatgatc ttttgggaac gcaacttcca agcaaaggct gacaagtgag
    34921 tgatgggcca aaagtagaga agacaagctc cgatggcaag aataatgaga atccagaaga
    34981 gcttggtatg tttgctttta gtctgcatct tttcgtcccc ctctccagag aagtaggata
    35041 aagacgagac taccgatgat tcctagcaag agactgacag acaactcata gggcctaatc
    35101 agaactcggg ataggatatc gcaagccaga actagattgg caccaaccag tgcgaccatg
    35161 agtttggttt gacttagatt atctccatag cgcttgcgaa caagattggg aacgataact
    35221 ccgagaaatg gtaagccacc cacggtaatc atggtgacgc ttgtcgttag cgccaccaga
    35281 aagagggcca gtttttcaag tagggagtag gaaatcccca aaccctcgct ggtttctttc
    35341 cccagattca tgatggtgaa ggtttgggat aatttccaaa cggttatcag gatgatgagg
    35401 cctaagaaga gccactcata ctgatgggtc tgaatcatgg agaaggagcc ctgggtccag
    35461 gcagtcatac tctgaaccag attgaaacga taggcgataa cttctgtgac tgagccgata
    35521 atcccgctat agatgatccc aatcagaggc aacatccacc tttcctttac agtaaaaatg
    35581 gtcataaagg ctaggaagaa gagggtgaat acgatggatg aaacaaaagc gaagagcatc
    35641 ttttgggtca gactagccga tggaaagaca aaaaggctca gcaccattcc cagtttggcg
    35701 gcttcagtcg ttccaactgt actcggtgca gcaaactgat tttgggtaat agtctgcatg
    35761 agaaggcctg ccatactcat actagaggca gtcaggagaa tactgatagt tcttgggaga
    35821 cgggactctt gaaagaggag ccaggtctgc tggtcgaaat caaatagctt tccccatgaa
    35881 aaatcactgg tcccaatgct aatagagaga aagactagga gtagaagtaa gccaattaaa
    35941 taatgagaaa gtttcatacc ccgtcctttc atgtagattt ggtatcgaaa gatatctgcg
    36001 gatataaatg taacattatt tttctaatct gtcaataaaa tttctgacaa tttaataaat
    36061 acaacaagga gagagcaaca agactttctc ctttgttatc ctattctaaa atgtttttac
    36121 cttaatctga taaaataata tcttcgaggg agtagctagc cgtccaatca agatattgtt
    36181 tagcttttga agcatctgct aggacactgg ctgggtcact agcacgtcga gcaacaatct
    36241 cgtgtgggat tttttaattt agtaattctt cagcagtttt aaagatttct ttgatagtat
    36301 agcctttttt agttcctaag ttaaagattt gagaagaact gtcttcttga aataggtagt
    36361 tcattccttt aacatgagcc tatgcaaggt ccaagacata aatgtaatct cgaatacatg
    36421 aaccgtcacg tgtatcgtag tcatctccaa atatttttaa gctatcatgt tgtcccaatg
    36481 cggtcttgtt gatatttgga atgatgtgag ttggattttt cacacgcaga ccgtttgaag
    36541 catccatttc agccccagca acattaaagt aacggaaaat aacatatttc cagtcgtagc
    36601 gattggccat ccagtaaatc attcgttcgc ccatcagttt tgtctctgca taagggttga
    36661 cagggtcgag cagggtatct tcagtcaccg gcttgtcaat acagttattt ccatagagag
    36721 aagcagtcga agagaacatg attttttgaa tgccaacttc agataagact ttgagaactt
    36781 ggttcatacc agcaacgttg gcagtgaagt atttacttgg attttcaata ctttcgctca
    36841 caacaatttc acctgcacaa tggaggacag catcaatctg attttcttct aagtaagcct
    36901 ttaaggcgct agcatcataa acatccagtt ctttaaagct agcacgacta tccacagccg
    36961 ctcgatttcc tgtggagaga ttatcgagga catgcacctg atagccagca tttaaaagag
    37021 ctttaacggt atgggagcca atgtagctag tcccacctgt aacaagaatt gttttggtca
    37081 tgattttttc cttttctagt tttgtactat agtaaattga aataagatat gaacaactct
    37141 attaggaaag tcgaattaat ttctagaaat gtttcagcag ctacagcgta ctattccaaa
    37201 ctcaaccaac tatatattta aagaaagaag aaagggaagt caactatttt ctgtaaattt
    37261 catgaaaaat ccaaacaact ttgatggtgt attgtttttt ttgtttggaa ataaatattc
    37321 gagttaattt tggaatgttt actagatttt gcactacatg caagagaata ctatcctttt
    37381 ctaagataga gcaggactaa gatactaact tagaaatcca ccttcccact atccttctcc
    37441 tataaaaagt ggtaaaatgg atgaaagaaa gaaggaactg aaatgacaac attattttca
    37501 aaaattaaag aagtaacaga acttgctgca gtctcaggtc atgaagcgcc tgtccgtgct
    37561 tatcttcgtg aaaagttgac accgcatgtg gatgaagtgg tgacagatgg cttgggtggt
    37621 atttttggta tcaaacattc agaagctgtg gatgcaccgc gcgtcttggt cgcttctcat
    37681 atggacgaag ttggttttat ggtcagcgaa atcaagccag atggtacctt ccgtgtcgta
    37741 gaaatcggtg gctggaaccc catggtagtt agcagccaac gtttcaaact cttgactcgt
    37801 gatggtcatg aaattcctgt gatttcaggt tctgttcctc cgcatttgac tcgtggaaag
    37861 gggggaccaa ccatgccagc cattgccgat atcgtttttg atggtggttt tgcggacaag
    37921 gatgaggcag aaagttttgg catccgtcct ggtgatacca tcgtaccaga tagttctgca
    37981 attttgacag ccaatgaaaa aaatatcatc tcaaaagctt gggataaccg ctacggtgtc
    38041 ctcatggtaa gcgagctagc tgaagcttta tcaggtcaaa aactcggcaa tgaactctat
    38101 ctgggttcta acgtccaaga agaagttggt ctgcgtggcg ctcatacctc tacaaccaag
    38161 tttgacccag aagtcttcct cgcagttgat tgctcaccag caggtgatgt ctacggtggt
    38221 caaggcaaga ttggagatgg aaccttgatt cgtttctatg atccaggtca cttgcttctc
    38281 ccagggatga aggattttct tttgacaacg gctgaagaag ctggtatcaa gtaccaatac
    38341 tactgtggta aaggcggaac agatgcaggt gcagctcatc tgaaaaatgg tggtgtccca
    38401 tcaacaacta tcggtgtctg cgctcgttat atccattctc accaaaccct ctatgcaatg
    38461 gatgacttcc tagaagcgca agctttctta caagccttgg tgaagaaatt ggatcgttca
    38521 acggttgatt tgattaaaca ttattaaacc ataagggagg tggtagggat ggcagaacca
    38581 aacctagaaa gccttataaa agatctttac aatcatgctc gacatgattt gagtgaagat
    38641 ttagttgctg ctctcctaga gactgctaaa aaactgccta ctacaaatga gcaattgcag
    38701 gcagttcgtc tctcaggcct ggtcaatcgt gaattgctcc taaatcccaa acatccagca
    38761 cctgagttgc tcaacttggc tcgctttatc aaaagagaag aagccaagta cagaggaact
    38821 gcgacttctg cgcttatgta tgaggaactc tttaaaatgc tttgattcca ttgtggatca
    38881 aagcattttt tgtaagatct atctcgtgag cgttcaaata gtagtaacaa ggaatcatga
    38941 gaagtcagcc gagcccatag tagtgaagaa acttctgtaa tggaagtgga gcgaagtgag
    39001 gaatcgtcaa acggtagggg ataggctgtt tgaagggtgc tacgaaaaag atagggtaag
    39061 gtgaaattat agcggaatga aataagatat gaacaaattg attgaggaaa ttaaatgaat
    39121 ttatagaaat cttttagcag tcatggtgtc ctattccagt ttcgaaatgc tataaatacg
    39181 aacaaattga ttgggaaatt caaatcgctt tctatcaatg ttttagaaga tacagtgctc
    39241 tagtctaact tcaatatact ataaaagaac agatggaagc aattatgatt tacttctatc
    39301 tttaaaataa atggtctgat aggaaaaatg tgtcccctca taaaatatag gatagtacga
    39361 atggaaggct tttgtagact ggaggacgaa ggagtttaga aactctcgtt aaaagttagt
    39421 tgagccggag tatggtggtg tggataatta tcaaaaatta tttctaaatc gaaatagttg
    39481 acagttagaa cgatgagtgt tacaattgtt ttattcattt cgatatcgaa ataaattgga
    39541 ggtgttatga aagatggtca tttgctagcc catcatattc gtttgttgaa tgggcggatt
    39601 tttcaaaagt tactgagtca agatcctgag gctctttata ggggtgaaca gggcaagatt
    39661 ttagcggttt tatggaatag tgaaactggc tgcgcaactg cgacagatat cgcgcttgcg
    39721 actgggcttg cgaataatac gctaacgact atgataaaaa agctagagga acaaaagctt
    39781 gtaattgtta gtccgtgtgg aaaagacaag cgtaagaagt atttagtttt aacggagtta
    39841 ggcaagtccc agaaagaagt ggggcatcgt gtcagtcaga aattggatac tatcttttac
    39901 aaaggatttt cagaggaaga aattcaccaa tttgaaggtt ttcaagaaag aattttggcg
    39961 aatttgaaag agaagggaaa tgaggtttag aatatgtcac aacaagtgaa aaatgctcac
    40021 aacctataca tccatgccat tcaagacgga cgagttgctg aggctcaagc ccagtctgta
    40081 ggggatacct atatccaaca ttcgacaggt gttcctgacg ggaaagaagg atttgcagcc
    40141 ttctttgcag atttctttga gcgtcatcca gagcgtcaga ttaagattgt ccgcaccatt
    40201 gaggatggca atctggtctt tgttcatgtt catcaatatc tgaatggtgg agaagctcaa
    40261 tgggtgacga cggatacttt ccgtgcggat gagaatggtc gtattgttga gcattgggat
    40321 gtcattgact actatcgaac acctgaaaat gatcaactag atcaaatttt tggagatttt
    40381 gaaatcaagg atttggacaa gaaagcagaa aataaaaaac tggttcgccg tttcttgaca
    40441 gaaattttcc aaaatgggga gctagagcag tggagtgatt atgtggcaga cgatttgatt
    40501 cagcataatc atgagattgg acaaggaagt gctgcttata aaaactatgt ggctgaatat
    40561 agtgtcactt ttgactttgt tttccaactc ttaggacaag gaaactatgt ggttagctat
    40621 ggtcagactc agattgatgg cgttgcttat gcccagtacg atatcttccg tttagagaac
    40681 gggaaaattg tggagcattg ggataataag gaagtcatgc ctaaggtaga agacttgact
    40741 aatcgaggga agttttaaat tgaggacaaa gaatgattga atacaaaaat gtagcactgc
    40801 gctacacaga aaaggatgtc ttgagagatg tcaacttaca gattgaggat ggggaattta
    40861 tggttttagt agggccttct gggtcaggta agacgaccat gctcaagatg attaaccgtc
    40921 ttttggaacc aactgatgga aatatttata tggatgggaa gcgcatcaaa gactatgatg
    40981 agcgtgaact tcgtctttct actggttatg ttttacaggc tattgctctt tttccaaatc
    41041 taacagttgc ggaaaatatt gctctcattc ctgaaatgaa ggggtggagc aaggaagaaa
    41101 ttacgaagaa aacagaagag cttttggcta aggttggttt accagtagcc gagtatgggc
    41161 atcgcttacc tagtgaatta tctggtggag aacagcaacg ggtcggtatt gtccgagcta
    41221 tgattggtca gcccaagatt ttcctcatgg atgaaccctt ttcggccttg gatgctattt
    41281 cgagaaaaca gttgcaggtt ctgacaaaag aattgcataa agagtttggg atgacaacga
    41341 tttttgtaac ccatgatacg gatgaagcct tgaagttggc ggaccgtatt gctgtcttgc
    41401 aggatggaga aattcgccag gtagcgaatc ccgagacaat tttaaaagtg cctgcaacag
    41461 actttgtagc agacttgttt ggaggtagtg ttcatgacta atttaattgc aacttttcag
    41521 gatcgtttta gtgattggtt gacagctcta tctcaacatt tgcagttgtc acttttgacc
    41581 ttgttactag ctattttgct tgcgattccc ttggctgttt ttcttcgcta tcatgagaag
    41641 ctggccgact gggtcttgca gattgcaggt attttccaga ccatcccgtc tctggccttg
    41701 ttggggctct ttatcccttt gatgggaatt gggaccttgc cggctttgac agctctagtg
    41761 atttatgcga tttttccgat tttacaaaat actattactg ggctgaaggg aattgatccg
    41821 agtcttcaag aggctgggat tgcctttggg atgaccagat gggagcgtct caagaagttt
    41881 gaaattccac ttgccatgcc tgttatcatg tctggaattc ggacggcagc ggtcttgatt
    41941 atcggtacgg ctaccttggc gaccttgatt ggggcagggg gactgggttc ctttatcctg
    42001 ttgggaattg accgtaataa tgccagtttg attttgattg gggccctttc ttctgcagtg
    42061 ctagctattg cctttaactt cctactaaaa gtaatggaaa aagcgaaatt gcggacgatt
    42121 ttctctggtt ttgccttggt ggctttatta ctgggtctgt cttatagtcc agcccttttg
    42181 gctcaaaaag agaaggaaaa cttgattatt gctgggaaaa taggcccaga accagaaatt
    42241 ttggctaata tgtataaatt gctgattgaa gaaaatacca gcatgactgc gactgttaaa
    42301 ccgaattttg ggacgacaag tttcctttat gaagctctga aaaaaggtga tattgacatt
    42361 tatcctgaat ttaccggtac ggtgactgaa agtttgcttc aaccatcacc caaggtgagt
    42421 catgagccag agcaggttta tcaagtggcg cgtgatggca ttgccaagca ggatcatcta
    42481 gcctatctca aacctatgtc ttatcaaaat acctatgctg tagctgttcc gaaaaagatt
    42541 gctcaagaat atggcttgaa gaccatttcg gatttgaaaa aagtggaagg gcagctgaag
    42601 gcaggcttta cgcttgagtt taacgaccgt gaagatggaa ataagggctt gcaatcaatg
    42661 tatggtctca atctcaatgt ggcgactatg cagccagctc ttcgttatca ggcaattcag
    42721 tcaggggata ttcaaatcac ggatgcctat tcgactgatg cggaattgga gcgttatgat
    42781 ttacaggtct tggaagatga caagcaactc ttcccacctt atcaaggggc tccactcatg
    42841 aaagaagctc ttctcaagaa acacccagag ttggaaagag ttcttaatac attggctggt
    42901 aagattacag aaagccagat gagccagctc aactaccaag tcggtgttga aggcaagtca
    42961 gcaaagcaag tagccaagga gtttctccaa gaacaaggtt tgttgaagaa atgatgggac
    43021 agagactt
//
LOCUS       DAVBOH010000014        40459 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOH010000014 DAVBOH010000000
VERSION     DAVBOH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.014"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..71
                     /locus_tag="VQ873_000813"
     tRNA            1..71
                     /locus_tag="VQ873_000813"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33..35,aa:Gly,seq:tcc)
     gene            106..179
                     /locus_tag="VQ873_000814"
     tRNA            106..179
                     /locus_tag="VQ873_000814"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:140..142,aa:Ile,seq:gat)
     gene            262..351
                     /locus_tag="VQ873_000815"
     tRNA            262..351
                     /locus_tag="VQ873_000815"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:298..300,aa:Ser,seq:tga)
     gene            365..438
                     /locus_tag="VQ873_000816"
     tRNA            365..438
                     /locus_tag="VQ873_000816"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Met,seq:cat)
     gene            442..514
                     /locus_tag="VQ873_000817"
     tRNA            442..514
                     /locus_tag="VQ873_000817"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Phe,seq:gaa)
     gene            527..607
                     /locus_tag="VQ873_000818"
     tRNA            527..607
                     /locus_tag="VQ873_000818"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:561..563,aa:Tyr,seq:gta)
     gene            612..682
                     /locus_tag="VQ873_000819"
     tRNA            612..682
                     /locus_tag="VQ873_000819"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:644..646,aa:Trp,seq:cca)
     gene            697..769
                     /locus_tag="VQ873_000820"
     tRNA            697..769
                     /locus_tag="VQ873_000820"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:His,seq:gtg)
     gene            783..854
                     /locus_tag="VQ873_000821"
     tRNA            783..854
                     /locus_tag="VQ873_000821"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:815..817,aa:Gln,seq:ttg)
     gene            864..947
                     /locus_tag="VQ873_000822"
     tRNA            864..947
                     /locus_tag="VQ873_000822"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:898..900,aa:Leu,seq:caa)
     gene            1054..2331
                     /locus_tag="VQ873_000823"
     CDS             1054..2331
                     /locus_tag="VQ873_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3107112.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2407..3891
                     /locus_tag="VQ873_000824"
     CDS             2407..3891
                     /locus_tag="VQ873_000824"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3107113.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3952..5232
                     /locus_tag="VQ873_000825"
     CDS             3952..5232
                     /locus_tag="VQ873_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3107114.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5236..5856
                     /locus_tag="VQ873_000826"
     CDS             5236..5856
                     /locus_tag="VQ873_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3107115.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6022..7200
                     /locus_tag="VQ873_000827"
     CDS             6022..7200
                     /locus_tag="VQ873_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3107116.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7713..8051
                     /locus_tag="VQ873_000828"
     CDS             7713..8051
                     /locus_tag="VQ873_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3107117.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8062..8430
                     /locus_tag="VQ873_000829"
     CDS             8062..8430
                     /locus_tag="VQ873_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3107118.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8537..9181
                     /gene="pcp"
                     /locus_tag="VQ873_000830"
     CDS             8537..9181
                     /gene="pcp"
                     /locus_tag="VQ873_000830"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3107119.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9209..10066)
                     /locus_tag="VQ873_000831"
     CDS             complement(9209..10066)
                     /locus_tag="VQ873_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3107120.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10196..11338
                     /gene="tgt"
                     /locus_tag="VQ873_000832"
     CDS             10196..11338
                     /gene="tgt"
                     /locus_tag="VQ873_000832"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3107121.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11439..13256
                     /locus_tag="VQ873_000833"
     CDS             11439..13256
                     /locus_tag="VQ873_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3107122.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13409..14560
                     /gene="nagA"
                     /locus_tag="VQ873_000834"
     CDS             13409..14560
                     /gene="nagA"
                     /locus_tag="VQ873_000834"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3107123.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14723..15781
                     /locus_tag="VQ873_000835"
     CDS             14723..15781
                     /locus_tag="VQ873_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3107124.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15932..16297
                     /locus_tag="VQ873_000836"
     CDS             15932..16297
                     /locus_tag="VQ873_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3107125.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16373..17314
                     /locus_tag="VQ873_000837"
     CDS             16373..17314
                     /locus_tag="VQ873_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3107126.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17262..18278
                     /locus_tag="VQ873_000838"
     CDS             17262..18278
                     /locus_tag="VQ873_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3107127.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18280..18606
                     /gene="comGC"
                     /locus_tag="VQ873_000839"
     CDS             18280..18606
                     /gene="comGC"
                     /locus_tag="VQ873_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3107128.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18599..19003
                     /locus_tag="VQ873_000840"
     CDS             18599..19003
                     /locus_tag="VQ873_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3107129.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19008..19268
                     /locus_tag="VQ873_000841"
     CDS             19008..19268
                     /locus_tag="VQ873_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107130.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19231..19692
                     /locus_tag="VQ873_000842"
     CDS             19231..19692
                     /locus_tag="VQ873_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3107131.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19670..20083
                     /locus_tag="VQ873_000843"
     CDS             19670..20083
                     /locus_tag="VQ873_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3107132.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20220..20814
                     /locus_tag="VQ873_000844"
                     /pseudo
     CDS             20220..20814
                     /locus_tag="VQ873_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20875..21828
                     /locus_tag="VQ873_000845"
     CDS             20875..21828
                     /locus_tag="VQ873_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3107133.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21879..23069
                     /locus_tag="VQ873_000846"
     CDS             21879..23069
                     /locus_tag="VQ873_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3107134.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23218..23589
                     /gene="rnpA"
                     /locus_tag="VQ873_000847"
     CDS             23218..23589
                     /gene="rnpA"
                     /locus_tag="VQ873_000847"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3107135.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23564..24388
                     /locus_tag="VQ873_000848"
     CDS             23564..24388
                     /locus_tag="VQ873_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3107136.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24407..25393
                     /locus_tag="VQ873_000849"
     CDS             24407..25393
                     /locus_tag="VQ873_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3107137.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25444..26067
                     /locus_tag="VQ873_000850"
     CDS             25444..26067
                     /locus_tag="VQ873_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3107138.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26198..27655
                     /locus_tag="VQ873_000851"
     CDS             26198..27655
                     /locus_tag="VQ873_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3107139.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27678..27959
                     /locus_tag="VQ873_000852"
     CDS             27678..27959
                     /locus_tag="VQ873_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3107140.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28036..28521
                     /locus_tag="VQ873_000853"
     CDS             28036..28521
                     /locus_tag="VQ873_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107141.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28538..29203
                     /locus_tag="VQ873_000854"
     CDS             28538..29203
                     /locus_tag="VQ873_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3107142.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29207..30070
                     /locus_tag="VQ873_000855"
     CDS             29207..30070
                     /locus_tag="VQ873_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3107143.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30072..30776
                     /locus_tag="VQ873_000856"
     CDS             30072..30776
                     /locus_tag="VQ873_000856"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3107144.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30955..32628
                     /locus_tag="VQ873_000857"
     CDS             30955..32628
                     /locus_tag="VQ873_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3107145.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32740..33831
                     /gene="ulaG"
                     /locus_tag="VQ873_000858"
     CDS             32740..33831
                     /gene="ulaG"
                     /locus_tag="VQ873_000858"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3107146.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33945..35921
                     /gene="tkt"
                     /locus_tag="VQ873_000859"
     CDS             33945..35921
                     /gene="tkt"
                     /locus_tag="VQ873_000859"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3107147.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36038..36337
                     /gene="yajC"
                     /locus_tag="VQ873_000860"
     CDS             36038..36337
                     /gene="yajC"
                     /locus_tag="VQ873_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3107148.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36383..36811
                     /locus_tag="VQ873_000861"
     CDS             36383..36811
                     /locus_tag="VQ873_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3107149.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36813..37223
                     /locus_tag="VQ873_000862"
     CDS             36813..37223
                     /locus_tag="VQ873_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107150.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37522..40173
                     /gene="adhE"
                     /locus_tag="VQ873_000863"
                     /gene_synonym="adhC"
     CDS             37522..40173
                     /gene="adhE"
                     /locus_tag="VQ873_000863"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3107151.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12276 a         7247 c         9107 g        11829 t
ORIGIN      
        1 gcgggtgtag tttagtggta aaactacagc cttccaagct gttgtcgcga gttcgattct
       61 cgtcacccgc tttgaacttt gttctttgta ccaagttttt gacttgggcg cgtagctcag
      121 gtggttagag cgcacgcctg ataagcgtga ggtcggtggt tcgagtccac tcgtgcccat
      181 agtgtttagt ccattactag gggattggaa tattatctgt tcactaagag gacacgggct
      241 tgttcccgta taaactattt tggaggatta cccaagtccg gctgaaggga acggtcttga
      301 aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc cacatcctcc ttttatatta
      361 ttaacgcggg atggagcagc tcggtagctc gtcgggctca taacccgaag gtcgtaggtt
      421 caaatcctgc tcccgcaata aggctcggta gctcagttgg tagagcaatg gattgaagct
      481 ccatgtgtcg gcggttcgat tccgtctcgc gccatttata tattttggaa gggtagcgaa
      541 gaggctaaac gcggcggact gtaaatccgc tccttcgggt tcgggggttc gaatccctcc
      601 ccttccattt tacgggcata gtttaaaggt agaactaagg tctccaaaac cttcagtgtg
      661 ggttcaattc ctactgcccg tgttaataga attatggcgg gtgtggtgaa gtggttaaca
      721 caccagattg tggctctggc atgcgtgggt tcgatcccca tcactcgcct attttatatt
      781 attggggtat agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa
      841 tccagctacc ccagttacta tttgccggcg tggcggaatt ggcagacgcg ctggactcaa
      901 aatccagtgt ccgcaaggac gtgccggttc gaccccggcc gccggtatag tatagtgtta
      961 ggaacgttgt tattcttcgt tcctttttta tattattttt ggtataatta tagttattca
     1021 aattttattt agattaagaa agtgtagggt agtatgtctt gttctatcga tttattaaaa
     1081 catcggtatt tgaaaaatat taaagaaaat cctgaattgt ttgtcggaat tgagttggag
     1141 tatcctgttg caagtttaga aggggatgct acagatgttg aagttataaa ggatctattt
     1201 cattatttag tttctacttt ggatctcacc gtagcaaagg tagatgattt tggcaatctg
     1261 atccagttag tagatccgat aagtcaggat gctattttat ttgaagtttc ctatacaacg
     1321 attgagtttg catttggtaa ggctgaaacg attcaagagg tcgaaaatcg tttcaataat
     1381 tatatgaatg taattcagag aaagttagct gaatcaaatc atgctattgt tggctgtggt
     1441 atccatccca actgggataa aaatgagaat tgtccagtgg cttatccacg ctatcagatg
     1501 ttgatggatt atttgaattt gagtagaaat attattaaat cagatttaca tcatttccct
     1561 gaatatggta cttttatctg tgggagccag gttcagctgg atatttcaaa aaccaactac
     1621 ttacgggtga ttaatgcttt tactcaaatt gaagcggcta aggcttattt atttgcaaac
     1681 tctgaatttt cgggtgcgga ttgggatacg aaaatttcaa gggatatttt ctgggaagaa
     1741 tctatgcatg gtatctatcc agagaatgtt ggggtcaatg ctagactcct taatgatgaa
     1801 gctgattttt ttgactatct aaatcattct gcgattttta ctgcggaacg tgatgggcag
     1861 acctattatt tttatcctat tcaggctggg gactatttgg ctacgtccga aatccaagca
     1921 tttgctctga atggggatga ggttattatt tacccccaag agaaggattt tgaaactcat
     1981 cgtagttacc agtaccaaga tttaacgact cgaggaacag ttgagtttcg tagtgtgtgt
     2041 acacagccac ttgataggac ttttgcttct gcagcttttc acttgggatt attggttaat
     2101 ttagacaagt tagaagctta cttagaaaca gcacctttct ttaaagtatt tggttatgat
     2161 tacaagtctt taaggagaca attttctaag aaaaatctta cagatgagga agaaactacg
     2221 attattgaat tttccaaaga cttactccta ctagctgagg agggactagt ggtgagaaat
     2281 aaggaagaaa tgacctattt acagcctttg agagaagaat tgagcctata atttctctta
     2341 taaagggaga attttctgaa aaatcatgat ataatggacg agactataga taaaggatag
     2401 agagtaatga cattagttta tcaatcaacg cgtgatgcca acaatacagt aactgccagc
     2461 caagcaattt tgcaaggttt ggcgacggac ggcggtttgt ttacaccggt tacttatcca
     2521 aaggtagatt tggactttga caaattgaaa gatgcttctt accaggaagt tgctaagcta
     2581 gttttgtcag catttttaga tgactttaca gctgaggagt tggactactg tatcaacaat
     2641 gcctacgata gcaaatttga tactccagct attgcaccat tagtgaaatt agatgggcaa
     2701 tacaatttgg aacttttcca tggttcaacg attgccttta aggatatggc cttgtctatt
     2761 ttgccatact ttatgacgac tgctgctaag aaacatggtt tggagaacaa gattgttatc
     2821 ttgacagcga catctggtga cacggggaaa gctgctatgg cggggtttgc ggatgtgcct
     2881 ggtactgaga ttatcgtctt ttatccaaag ggtggtgtca gcaaggtaca agagttgcaa
     2941 atgaccactc agaatggtga caatactcat gttattgcta ttgatggtaa ttttgacgat
     3001 gcgcaaacaa atgtgaagca catgtttaac gacgtggctc ttcgtgaaaa attgactacc
     3061 aacaagttgc aattttcatc agctaactct atgaacattg gtcgtctggt gccacaaatt
     3121 gtttattatg tttatgctta cgctcaattg gttaagactg gtgaaattgt agctggtgaa
     3181 aaggttaact tcacagtacc aacaggaaac tttggaaata tcttggctgc cttttatgcc
     3241 aaacaaatcg gcctaccagt tggcaagcta atctgtgctt caaatgacaa taatgtcttg
     3301 acagacttct ttaaaacacg tgtctatgac aaaaaacgtg agtttaaggt aacaaccagc
     3361 ccatctatgg atatcttggt atcttcaaac ttggagcgct tgattttcca tcttttggga
     3421 aataatgctg aaaagacagc tgaacttatg aatgccttga acacgcaagg acaatataag
     3481 ttgacagact ttgatgcaga gattttggac ctctttgcag ctgaatatgc gactgaggaa
     3541 gaaacagcgg cagaaatcaa gcgtgtttat gagtcagatt cttatattga ggatccacat
     3601 acggcggttg cctcagcagt ttatagaaaa taccaagcgg ttactggaga tgtaactaag
     3661 acagtgattg cttcaacagc tagtccatac aagttcccag tagttgcagt agaagctgta
     3721 actggaaaag caggtttgac agactttgaa gccttggctc aattacatga aatctcaggc
     3781 gttgcagtgc caccagcagt tgatgggctt gaaatagctc caattcgtca caagacaaca
     3841 gtggcagctg ctgacatgca agcagcggtt gaggcttatt taggacttta agacagaggg
     3901 agcaaactcg gttgggaaac caactgagtt tcttttcatc aggaggagag attgtttaag
     3961 aaaaataaag acattcttaa tattgcattg ccagctatgg gtgaaaactt tttgcagatg
     4021 ctaatgggaa tggtggacag ttatttggtt gctcatttag gattgatagc tatttcaggg
     4081 gtttcagtag ctggtaatat tatcaccatt tatcaggcga ttttcatcgc tctgggagct
     4141 gctatttcca gtgttatttc aaaaagcata gggcagaaag accagtcgaa gttggcctat
     4201 catgtgactg aggcgttgaa gattacctta ctattaagtt tccttttagg atttttgtcc
     4261 atcttcgctg ggaaagagat gataggactt ttggggacgg agagggatgt agctgagagt
     4321 ggtggactgt atctatcttt ggtaggcgga tcgattgttc tcttaggttt aatgactagt
     4381 ttgggagcct tgattcgtgc aacgcataat ccacgtctgc ctctctatgt tagtttttta
     4441 tccaatgcct tgaatattct tttttcaagt ctagctattt ttgttctgga tatggggata
     4501 gctggtgttg cttgggggac aattctgtct cgtttggttg gtcttgtgat tttgtggtca
     4561 caattaaaac tgccttatgg gaagctaact tttggtttag ataaggaact gttgaccttg
     4621 gctttaccag cagctggaga gcgacttatg atgagagctg gagatgtagt gatcattgcc
     4681 ttggtcgttt cttttgggac ggaggcagtt gctgggaatg caatcggaga agtcttgacc
     4741 cagtttaact atatgcctgc ctttggtgtc gctatggcaa cggtcatgct gttggcccga
     4801 gcagttggag aggatgattg gaaaagagtt gctagtttga gtaaacaaac cttttggctt
     4861 tctctgttcc tcatgttgcc cctgtccttt agtatatatg tcttgggtgt accattaact
     4921 catctctata cgactgattc tctagcggtg gaggctagtg ttctagtgac actgttttca
     4981 ctacttggta cccctatgac gacaggaaca gtcatctata cggcagtctg gcagggatta
     5041 ggaaatgcac gcctcccttt ttatgcgaca agtataggca tgtggtgtat ccgcattggg
     5101 acaggatatc tgatggggat tgtgcttggt tggggcttgc ctggtatttg ggcagggtct
     5161 ctcttggata atggttttcg ctggttattt ctacgctatc gttaccagcg ctatatgagc
     5221 ttgaaaggat aggaaatgca aaaaacagct tttatttggg atttagacgg gactttattg
     5281 gactcttacg aagcgatttt atcagggatt gaggagactt ttgctcagtt ttctattcct
     5341 tatgataagg agaaggtgag agagtttatc ttcaagtatt cggtgcaaaa tttgcttgtg
     5401 cgggtggcag aagatagaaa tctggatgtt gaggtgctaa atcaggtgcg tgcccagagt
     5461 ctggctgaga agaatgctca ggtagttttg atgccaggtg cgcgtgaggt gctagcttgg
     5521 gcagacgaat caggaattca gcagtttata tatactcata aggggaacaa cgcttttacc
     5581 attctcaagg acttgggggt ggaatcctat tttacagaga ttttaaccag tcagagtggc
     5641 tttgtgcgga agccaagtcc agaagcggct acctatctgc tagataagta tcagttgaat
     5701 tctgataata cttattatat aggggatcgg actctggatg tggaatttgc ccagaatagt
     5761 gggattcaaa gtatcaactt tttagagtct acttatgaag ggaatcacag gattcaagcg
     5821 ttagcagata tttcccgtat ttttgagact aagtgataaa aagattgtgt cagttttgtg
     5881 acagagacct aacaaactat ttcaagtaat ctagtttgtt acaaggaata gacagttctg
     5941 ttaaataggc ccgagagggc tttttttcta cattttttgt gttatgatag acaggtactc
     6001 atttgaaagg aatttgaagg aatgaagaaa agaatgttat tagcgtcaac agtagccttg
     6061 tcatttgccc cagtattggc aactcaagca gaagaagttc tttggactgc acgtagtgtt
     6121 gagcaaatcc aaaacgattt gactaaaacg gacaacaaaa caagttatac cgtacagtat
     6181 ggtgatactt tgagcaccat tgcagaagcc ttgggtgtag atgtcacagt gcttgcgaat
     6241 ctgaacaaaa tcactaatat ggacttgatt ttcccagaaa ctgttttgac aacgactgtc
     6301 aatgaagcag aagaagtaac ggaagttgaa atccaaacac ctcaagcaga ttctagtgaa
     6361 gaagtgacaa ctgcgacagc agatttgaca accaatcaag tgaccgttga tgatcaaact
     6421 gttcaagttg cagatctttc tcaaccaatt gcagaagctc caaaagaagt agcatcaaat
     6481 tcagaagttg cagagacagt gactgctgca gaagaagtgg cactatctac agactctact
     6541 acgccagagg gacaaccagc cgaaacaact agtccagttg aagaagtagc tcctcaggca
     6601 acgactctag ctgagaagca ggaaacacaa gtgagctctc aaaccgagtc agcagtggaa
     6661 gcaactacaa tgccagtaga agaaaaagca accgaagcaa ctacaacaag ttcagaagca
     6721 aaagaagtag catcatcaaa tggagctaca gcagcagttt ctacttatca accagaagag
     6781 acgaaaataa tttcaacaac ttacgaggct ccagctgcgc ccgattatgc tggacttgca
     6841 gtaacaaaat ctgaaaatgc aggtcttcaa ccacaaacag ctgcctttaa agaagaaatt
     6901 gctaacttgt ttggcattac atcctttagt ggttatcgtc caggagacag tggagatcac
     6961 ggaaaaggtt tggctatcga ttttatggta ccagaacgtt cagaattagg ggataagatt
     7021 gcggaatatg ctattcaaaa tatggccagc cgtggcatta gttacatcat ctggaaacaa
     7081 cgtttctatg ctccattcga tagcaaatat gggccagcta acacttggaa tccaatgcca
     7141 gaccgtggta gtgtgacaga aaatcactat gaccacgttc acgtttcaat gaatggataa
     7201 acccgacttg gtaacatcat tttgacgaat gagatctagc tttcgtgata ggaagcgatt
     7261 ctcgttcgtt ttttctttgt catactcttc gaaaatctct tcaaacaacg tcagttttat
     7321 ctgaaacctc aaagctgtgc tttgagcaac ctgcgactag cttcctagtt tgctttttga
     7381 ttttcattga gtatcaattt gaatggaaaa tggaaagtta tcatcttgta atgagttaag
     7441 caacattctt gcaatctatt ttatagtaga ttgaaactag aatagtacac aactgcttct
     7501 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgtcctgctc ttatttcatt
     7561 tcactatact ttatattata attgactggt caaatattga taaatcaata aaaagagagg
     7621 ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg agcaagtgag
     7681 tacgcaattg tttgaaaaag cttgggatta gtttgacacg gtatcagatt ttactgtttt
     7741 tgctggagca ttctccttgt aaccaaatgg cggttcagga gcgtttgaaa attgatcagg
     7801 ctgctttgac acggaatttc aagattttgg aaacggaagg tttggtggag cgtcatcgta
     7861 atcctgaaaa tcagcgggaa gtattggtag aggctgcgaa gtatgccaag gagcagttag
     7921 tggtgaatcc ccctctgcag catatcaagg ttaaggaaga gatggaaagt atcttaacag
     7981 agtttgagag aacagaactc agccgtttat taaataaatt ggttttgggt attgaaaata
     8041 tagaaattta aggagaaata gatgtcaatt attacaatta ttttaacaac gatcgttgct
     8101 ttggagcatt tttacatttt ttatttggaa agtattgcca cgcaatcaga tgcgactagt
     8161 cgtgtattta atatggaaaa ggaagaattg gctcatccgt cagtaagttc attgttcaaa
     8221 aatcaaggga tttataaggc tctgctagga gtctttctct tgtatgtcat ttatttctca
     8281 cagaatttag aaattgtgac tatttttgtc ttatttgtga ttggtgctgc gacttacggc
     8341 tctttaacag cggataaaaa aattattttg aagcaaggtg gatcagctat tttggccttg
     8401 attagtattt tactctttaa atacacttga aggtcgattt taatctcgct aatccttttt
     8461 aatccagaat aagggaaata tgttatactt gtttttaaga aaaaagtctc attgaattgg
     8521 ttttgaggag ttagaaatga aagtattagt gacaggtttt gagccctttg gaggggaaaa
     8581 gggcaatcca actttggagg ccattaaagg tttaccagct gaaatccatg gtgctgaggt
     8641 ccgttggcta gaggtgccga cagtttttca caaatctgct caagtattgg aagaagagat
     8701 gaatcgttat caacctgact ttgtcctttg tattgggcaa gctggtggaa gaactagtgt
     8761 gacacctgaa cgagtggcca ttaatcaaga cgatgcacgc atttctgata acgaagataa
     8821 tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg gcctacttta gtagtttgcc
     8881 gattaaagcg atggttcaag ctataaaaaa agagggctta ccggcctctg tttccaatac
     8941 ggcagggact tttgtctgca gccatttgat gtatcaggct ctctatttgg tagaaaagaa
     9001 atttccatat gttaaggcag gttttatgca tattccttat atgatggaac aggtggtgaa
     9061 cagaccgact actccaacta tgagtttagt ggatattcgg cgagggatag aagcagcaat
     9121 cggcgctatg atagaacatg gagatcagga actcaagttg gtaggcggag aaactcattg
     9181 atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg acgttttcga gccaatactg
     9241 ctcggtaaaa cataatttta gtgcattgga tataaggtag gagtgaaaaa ctagcaatgc
     9301 caaaggtaat ccaattgagg aagtaccaag gaagaagctg taaatctagg acaaagtgct
     9361 ggaacttgta gcccttcata aaggaacggc tagtttttag gattcgtctt ggtgggacct
     9421 gtcctaggtc tagactataa cagagaagaa attccacctg tgaataggca taatactgtg
     9481 gaatatagag gatatttcct acaatgatca agatgagact tgcaagaaag tagagtccaa
     9541 agaccatgag gaaacgctcg gtttcaactg atgagagatc tagatttgga aactcaggat
     9601 gtagggtgac gaattttttg gctaaaaagc tactataaaa gaggaggtaa atcccaagta
     9661 aattagggat actccataaa aagagataga aacgtttgag aagtagggtc aaaaaggttt
     9721 gagaaaagcg ctcctcatca aagagagcta ggctgttttt tacagatggc tccgttttag
     9781 aatctttcat gagtgtcagt gttgcataga cggaactggt caaaagaata gtcccgataa
     9841 aggagactag tagaggaaag aggtaggttt gaagtatttg gccaagtatg ctgaaaaatg
     9901 gctgttctaa aacagtcccg tggatccgag ataagggatt aagaaaacca gataagatga
     9961 ccagcatact gggaaggata tagaggagaa agagacgggg ggtgtcagcc tgaaaatgtt
    10021 ttgactcctg acgaattgtt tttaaatcaa tttttggata gttcattctc ttattatacc
    10081 atagttctta tacatagttc gtgacagttc ctactttttt tgataaaatc atacagtgtg
    10141 tccttgggca cactgtatga actgggactg tctttcccag cttcggaggt aaaaaatgtc
    10201 agattcacca atcaaatatc gtttgattaa gaaagaaaaa cacacaggag ctcgtctagg
    10261 agaaatcatc actccccacg gtacctttcc gacacctatg tttatgccag ttgggacaca
    10321 agccactgtc aaaactcagt cacctgaaga attgaaggag atgggttcgg gaattatcct
    10381 atcaaacacc tatcatctct ggcttcgccc tggagatgaa ctcattgcac gcgctggtgg
    10441 tctccacaag ttcatgaatt gggaccagcc tatcttgaca gatagtggtg gttttcaggt
    10501 ttattcttta gcagatagcc gtaatatcac agaagaagga gtaaccttta aaaatcatct
    10561 aaatggttct aagatgctcc tatccccaga aaaagccatc tctattcaga ataatctggg
    10621 ttcagacatc atgatgtcct ttgatgaatg tcctcagttt tatcaacctt atgactacgt
    10681 taagaaatcg atcgagcgta ccagccgttg ggctgagcgt ggtttgaagg ctcaccgtcg
    10741 tccacatgac caaggtttgt ttggaattgt gcaaggtgca ggatttgaag accttcgccg
    10801 ccaatcagct cacgatcttg tcagcatgga tttctcaggc tactctatcg gtggtttggc
    10861 agtgggagaa acccatgaag agatgaatgc ggtcttggac tttacaactc aactgctgcc
    10921 tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca gatagcttga tcgatggggt
    10981 cattcgtggg gtggatatgt ttgactgtgt cttaccgact cgaattgctc gtaacgggac
    11041 ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc cagtttgctg aggactttac
    11101 gccactggat cctgagtgtg attgctacac atgtaataac tatacacgcg cttaccttcg
    11161 tcacctgctc aaggctgatg aaacctttgg tatccgcttg actagctacc acaatcttta
    11221 cttcttgctt aacctgatga agcaagtgcg acaagccatc atggatgaca atctcttgga
    11281 attccgtaag tattttgtgg aaaaatatgg ctataataag tcaggacgta atttctaaaa
    11341 tggaattgat ataagctaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11401 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11461 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11521 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11581 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11641 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11701 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11761 ttatgaccaa cttctatgaa ctcttaacag gtgggagtta tgaatctcag ttcattcctc
    11821 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11881 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatgatct
    11941 ttctcttatc tgctactgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    12001 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    12061 tgggaagtat gttagcaact attgtaggcg ttcgtcagac gacttccctc gtcaagcagt
    12121 tggataaaat ctgggattta cgaaagactt tagtagtttt tggaggaggc tttggtttcc
    12181 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12241 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12301 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12361 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12421 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattttat gtattggaac
    12481 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12541 acgcaattct tgcagcaggt acaggaatct tgaccttcat tgtctgcatg gtgaccttgt
    12601 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12661 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12721 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12781 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12841 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12901 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12961 ctaagggaca ccatatgatt ttggtgactc cttatgaggg tgataagaca aaagagacct
    13021 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    13081 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    13141 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13201 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13261 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13321 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13381 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13441 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttggaaa
    13501 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13561 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13621 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13681 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13741 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13801 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13861 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13921 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13981 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    14041 tgtttgggtg catgcctaca atggaatgcg tgggttgact caccgtgaat tgggtatggt
    14101 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    14161 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14221 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14281 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14341 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14401 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14461 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14521 agcaacctac ctagatggcg tgaaacgtta tcaagcataa gagagaaggc agaagttaga
    14581 gactaacttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14641 acaaaaaaag cttgaagaaa caaagaaaaa tgcttacaat tgaactataa atattacaaa
    14701 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14761 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14821 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14881 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14941 ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    15001 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    15061 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    15121 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15181 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15241 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15301 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15361 gactcataag gttaattctt cagaccctaa aaaagccatt aaagaaattt atgatttgac
    15421 agatggtcgt ggtgtggatg tcgctatcga agctgtaggg attcctgaaa catttgattt
    15481 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15541 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15601 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccgga
    15661 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctacg aagtcttcag
    15721 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15781 agtagtaaaa atatttttgt acataagcaa atagaaattc agtcatccat cagatggctg
    15841 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15901 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15961 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    16021 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    16081 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    16141 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16201 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16261 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16321 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16381 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16441 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16501 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16561 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16621 gaagatggcg tctctacgtt tatctactgt aggcgattat cggggacatg agagtttggt
    16681 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16741 attaggcaag cagtacaggc aacggggact ctatcttttt gctggcccgg ttgggagtgg
    16801 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16861 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16921 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16981 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    17041 aggtgcgaca gtcttttcaa ccattcacgc caagagtatc cgaggtgttt atgagcgtct
    17101 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    17161 gagattaatc gggggaggag gaatcgttga ctttgcaaac agagattatc aagaacacca
    17221 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17281 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17341 acaatctctt ttctagcggt tttcatctgg tggagactat ctccttttta gataggagtg
    17401 ctttgttgga caagcagtgt gtgatccaga tgcgtgtggg cttgtctcag gggaaatcat
    17461 tctcagaaat gatggaaagt ttgggatgtt caagtgctat tgtcactcag ttatccctag
    17521 ctgaagttca tggcaatctc cacctgagtt tgggaaagat agaagaatat ctggacaatc
    17581 tggccaaggt caagaaaaaa ttgattgaag tagcgaccta tcccttgatt ttgctgtttt
    17641 ttcttctctt aatcatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17701 atattgccac ccgaattatc ggtaatctgc cccaaatttt tctaggcatg gcagggcttg
    17761 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgaatgtct
    17821 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctat ttgacagcct
    17881 attatgcacg tgaatggggg aatatgattt cacagggaat ggagttgacg cagatttttc
    17941 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    18001 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    18061 aattgagtct catcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    18121 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18181 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18241 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18301 ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga tgttggtggt cttgctgatt
    18361 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18421 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagcttg
    18481 gaaaagaatg aagatgctag cctaagcaag ttaaaagacg atgggcgaat cacggaagaa
    18541 caggttaaag cttataaaga atacaatgat aaaaatgtag gagcaaatcg taaagtcaat
    18601 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggtcttgtga gtatccttgc
    18661 cttgggcttg tccggctctg ttcagtccac ttttgcggca gtagaggaac agattttctt
    18721 tatggaattt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18781 gactagtctg aacttagatg ggcagacgat tagcaatggc agtcaaaagt tgccagtccc
    18841 taaaggaatt caggtcccat caggccaaag tattacattt gaccgtgctg ggggcaattc
    18901 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18961 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    19021 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    19081 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    19141 agatggcctt gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19201 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19261 agccataagg tcaaggcttt taccttgtta gaatccctgc ttgccctcat tgtcatcagt
    19321 gggggattac tcctttttca agctatgagt cagctcctca tttcagaagt tcgctaccag
    19381 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggt agaattagac
    19441 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19501 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19561 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19621 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19681 gaagaaagtt aaggcaggtg ttctcctcta tgcagtcacc atggcagcta tctttagtct
    19741 tttgttgcaa ttttacttga accgacaagt cgcccactat caagactatg ctttgaataa
    19801 agaaaaattg gttgcttttg ccatggctaa acgaaccaag gataaagccg agcaagaaag
    19861 tggggaacag gtctttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19921 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19981 agaagagaaa agagataaaa aggaagaggt agcgaccgat tcaagcgaaa aagtggagaa
    20041 gaaaaaatca gaagagaagc ctgaaaagaa agagaattcc tagtcaattc aactataatg
    20101 cgttgaatca agaatagtcc actatagttt ctagaaaatt gctggaaatg gatgttaagc
    20161 tccaattcat ttgtttatat cttatttcag tttactatac tttgtgctaa attaaagata
    20221 tgaaacatga ttttaaccac aaagcagaaa ctttcgattc ccctaaaaat atcttcctcg
    20281 caaacttggt atgtcaagca gccgagaaac agattgatct tctatcagac aaagaaattt
    20341 tagatttcgg tggtgacacg ggtctattag ccttgcccct agcccctagc caagcaggct
    20401 aagtcagtca ctcttgtaga catttctgag aaaatgttgg agcaagctcg tttgaaagtg
    20461 gagcagcaag caatcaagaa tatccagttt ttggagcaag atttaccgaa aaatcccttg
    20521 gagaaagagt ttgattgcct tgctgttagt cgggttcttc atcatatgcc tgatttggat
    20581 gcggctctat cactgtttca tcaacatttg aagtaagatg ggaaactcat cattgctgat
    20641 tttaccaaga cagaagctaa tcatcatgga tttgatttag ctgaactgga aaacaagcta
    20701 attgagcatg gtttttcatc tgtgcatagt cagattctct atagcgctga agacttgttt
    20761 caaggaaatc actcagaatt ctttttaata gtagcccaaa aatcactcgc ctagtcaggg
    20821 agtgattttt ctataaggat ggaaaaaaga agggaaattt gataagatag gaatatggat
    20881 tttgaaaaaa ttgaacaagc ttatacctat ttactagaga atgtccaagt catccaaagt
    20941 gatttggcga ccaactttta tgacgccttg gtggagcaaa acagcatcta tctggatggt
    21001 gaaactgagc taaaccaggt caaagacaac aatcaggccc ttaagcattt agcactacgc
    21061 aaagaagaat ggctcaagac ctaccagttt ctcttgatga aggctgggca aacagaaccc
    21121 ttgcaggcca atcaccagtt tacaccggat gctattgctt tacttttggt gtttattgtg
    21181 gaagagctgt ttaaagagga ggaaattact atcctcgaaa tgggttctgg gatgggaatt
    21241 ttgggcgcta ctttcttgac ctcgcttact aaaaaggtgg attatttggg aatggaagtg
    21301 gatgatttgc tgattgattt ggcagctagc atggcagatg taattggttt gcaggctggc
    21361 tttgtccaag gagatgccgt tcgtccacaa atgctcaaag aaagtgatgt ggtcatcagc
    21421 gacttgcctg ttggctatta tcctgatgat gccgttgcgt cgcgccatca agttgcttct
    21481 agtcaagaac atacttacgc ccatcacttg ctcatggaac aaggacttaa gtacctcaag
    21541 tcagacggat acgctatttt tctagctccg agtgatttgt tgaccagtcc tcaaagtaat
    21601 ttgttgaaag tctggttgaa agaggaggca agtctggttg ctatgattag tttacctgaa
    21661 aatctctttg ctaatgctaa acaatctaag actattttta tcctacagaa gaaaagtgaa
    21721 atagcagtag agccttttgt ttatccactt gctagcttgc aagatgcaag tgttttaatg
    21781 aaatttaaag aaaattttca aaaatggact caaggtactg aaatataaaa tagattttgt
    21841 tataatagtt gaaaacgctt aaaaaggggt atcatgttat gacaaaaaca attgcaatca
    21901 atgcaggaag ttcaagtttg aaatggcaat tatacttaat gccagaagaa aaagtattgg
    21961 cgaaaggttt gattgaacgt atcggtttga aagattcaat ttcaactgta aaatttgacg
    22021 gccgttctga acaacaaatt ttggatattg aaaatcatac acaagctgtt aaaattttat
    22081 tggatgactt gattcgtttc gatattatca aggcttatga cgagattaca ggtgttggac
    22141 atcgtgttgt tgctggtgga gaatatttca aagaatcaac agttgttgag ggagatgttt
    22201 tagaaaaagt tgaagagttg agtttgttgg ctcctctaca caacccggca aatgcagcag
    22261 gtgttcgtgc cttcaaggaa ttgttgccag acattaccag tgtagttgtt tttgatactt
    22321 ccttccacac aagtatgcca gagaaagctt atcgctaccc tctaccaaca aaatattaca
    22381 cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag tcaccagttt gtagcaggag
    22441 aagctgcaaa actcttggga cgtccattag aagacttgaa gttaattacc tgtcatattg
    22501 gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc tgtagacact tctatggggt
    22561 tcactcctct tggtggtatt atgatgggaa cgcgtacagg ggatattgat ccagctatca
    22621 ttccttattt aatgcaatat acagaggatt ttaacacacc agaagatatc agtcgtgttc
    22681 ttaaccgtga atcaggtctt ttgggagttt ctgctaattc tagcgatatg cgcgatatag
    22741 aagcagctgt agcagaaggg aatcacgagg ctagcttggc ttatgaaatg tatgttgacc
    22801 gtatccaaaa acatatcggt cagtaccttg cagtgctaaa tggagcagat gccattgttt
    22861 tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg tgatgtaatc tcagggattt
    22921 cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt tggcgttaca ggagacatct
    22981 caacagaggc agctaaaatc cgtgtcttgg ttattccaac agatgaagaa ttagtcattg
    23041 cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa aaaatattca atacaaggag
    23101 ttgggaaagt tatttttcca gcttcttttt ctgatgaaat tgtccaaaac cttgctatga
    23161 ttggcttttt tgaaaaatat ggtataatag tagtaattta atagatggag ttgagttttg
    23221 aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg cgattttcaa ggaggggaca
    23281 agttttgcta atcgcaaatt tgtggtctac caattagaaa accagaaaaa ccattttcga
    23341 gtaggtctat cagttagcaa aaaactgggg aatgccgtca ctagaaatca aattaagcga
    23401 cggattcggc atattatcca gaatgcaaaa gggagtctgg tagaagatgt cgactttgtt
    23461 gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag agatggagaa aaatctactc
    23521 catgtattaa aattatcaaa gatttaccgg gaaggaaatg ggagtgaaaa agaaactaaa
    23581 gttgactagt ttgctaggac tgtctctgtt aatcatgaca gcctgtgcga ctaatggggt
    23641 aactagcgat attacagccg aatcggctga tttttggagt aaattggttt acttctttgc
    23701 ggaaatcatt cgctttttat cgtttgatat tagtatcgga gtggggatta ttctctttac
    23761 ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg caaatggtgg cttctaggaa
    23821 aatgcaggaa gctcagccac gcattaaggc gcttcgagaa caatatccag gtcgagatat
    23881 ggaaagcaga accaaactag agcaggaaat gcgtaaagta tttaaagaaa tgggtgtcag
    23941 acagtcagac tctctttggc cgattttgat tcagatgccg gttattttgg ccctgttcca
    24001 agccctatca agagttgact ttttaaagac aggtcatttc ttatggatta accttggtag
    24061 tgtggataca acccttgttc ttccgatttt agcagcagta ttcacctttt taagtacttg
    24121 gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg actgcgatga tgtatgggat
    24181 tccagtcttg atttttatct ttgcagttta tgcgccaggt ggagtcgccc tatactggac
    24241 agtgtctaat gcttatcaag tcttgcaaac ctatttcttg aataatccat tcaagattat
    24301 cgcagagcgc gaggccgtag tacaggcaca aaaagatttg gaaaatagaa aaagaaaagc
    24361 caagaaaaag gctcagaaaa cgaaataaat aaggaggaat ctggtaatgg tagtatttac
    24421 aggttcaact gttgaagaag caatccagaa aggattgaaa gaattagata ttccaagaat
    24481 gaaggctcat atcaaagtca tttctaggga gaaaaaaggc tttcttggtc tatttggtaa
    24541 aaaaccagcc caagtggata ttgaagcgat tagtgaaacg actgttgtca aagcaaatca
    24601 acaggtagta aaaggcgttc cgaaaaaaat caatgatttg aacgagcctg tgaagacggt
    24661 tagtgaagaa accgttgacc ttggtcatgt ggttgatgct attaaaaaaa tagaggaaga
    24721 aggtcaaggt atttctgatg aagtcaaggc tgaaatctta aaacatgaaa gacatgccag
    24781 cactatctta gaagaaactg gtcacattga gattttaaat gaacttcaaa tcgaggaagc
    24841 gatgagggaa gaagcaggcg ctgatgacct tgaaactgag caagatcaaa ctgaaaatca
    24901 agacttgaaa gagatgggct tgaaggtcga gcaaagttat gatattgccc aggtggctac
    24961 ggatgtgact gcctatgttc aagcgattgt ggatgacatg gatgttgaag ctacactttc
    25021 aaatgattat aaccgtcgta gcatcaatct acaaattgac accaacgaac caggtcgtat
    25081 tatcggctac catggtaaag tcttgaaggc cttgcaactg ttggctcaaa attatcttta
    25141 caaccgctat tccagaacct tctacgttac aatcaatgtc aatgattatg tcgaacaccg
    25201 tgcagaagtc ttgcagacct atgcgcaaaa attggcgact cgtgttttgg aagaagggcg
    25261 cagtcataaa acagatccaa tgtcaaatag cgaacgcaag attatccatc gtattatttc
    25321 acgtatggat ggcgtgacta gttactctga aggtgatgag ccaaatcgct atgttgttgt
    25381 agatacagaa taagtaaaat caggtttatc ctgatttttt gctagttaga ggaggttaaa
    25441 ctgatgttga ataagataag agactattta gactttgctg gtttgcagta ccgtaatcct
    25501 gataaagcgg gagcagagcg agagaagatg ctggcattcc gccacaaagg acaagaggcc
    25561 cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa gccatccaga atggcaactc
    25621 caacagacta gccagtggat gaatcaggcc cagcgtttga gaccacattt ttgggtttat
    25681 ctacagagag acggacaagt gacagaacct atgatggcct tacgtttgta tgggacatct
    25741 actgactttg gaatttcttt ggaagtcagt ttcatcgaac gtaagaagga tgagcaaaca
    25801 ctgggcaagc aggccaaagt tttagacatt ccaaccgtta aagggattta ttatctaacc
    25861 tactctaatg gtcaaagtca acggtgggag gcgaatgaag aaaagcgtcg tactttacgc
    25921 gagaaggtga gaagtcaaga agttcgaaaa gttttagtga aggtagatgt tcctatgaca
    25981 gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga agtcttattc taaaattctt
    26041 ccctattatc tagctacgag aaaataagat aatttgtaaa acatcataaa tcatacagtc
    26101 caagagtgaa cagtccgctg tgtaattctt ggtctttttg tttgcgcttt cgcattatat
    26161 aataaactta caaaaacaat tcaaaaggag aacaattatg gaagtcgttt caagtgttct
    26221 aaattggttt tctagcaata ttttgcagaa tcccgcattt ttcgtaggtt tattggtgtt
    26281 gataggatat gcacttttga aaaaacctgc ccatgacgtt ttttcagggt ttgttaaagc
    26341 aacagtaggg tatatgttgc ttaacgtggg tgctggtggt ttggttacaa cctttcgtcc
    26401 aatcttagca gctcttaact acaaattcca aattggtgca gcggttatcg acccttactt
    26461 tggacttgct gcagcaaaca acaaaattgc agcagagttt ccagattttg ttggaactgc
    26521 aactacagct ctattgattg gttttggaat aaatatcttg ctcgtagctc ttcgaaagat
    26581 tacgaaggta agaaccctct ttattactgg tcacatcatg gtacaacaag ctgcaacagt
    26641 atctcttatg gttctattct tagtaccaca attgcgcaat gcttacggta cagcagcgat
    26701 tggtatcatc tgtggacttt actgggcagt tagttcaaat atgactgttg aggcaactca
    26761 acgcttgact ggtggtggcg gatttgcgat tggtcaccaa cagcaatttg caatctggtt
    26821 tgtagataaa gtagcaggac gctttggtaa gaaagaagaa agtttagaca atcttaaatt
    26881 acctaagttc ctctcaatct tccacgatac agttgttgca tctgctacct tgatgctcgt
    26941 attcttcgga gccattcttt taatcttggg tccagacatt atgtctaata aagaagtcat
    27001 cacttcagga actctattca atcctgctaa acaagatttc tttatgtaca ttatccaaac
    27061 agcctttacc ttctcagttt acttgttcgt tttgatgcaa ggtgtccgaa tgttcgtatc
    27121 tgagttgaca aacgccttcc aaggtatttc aaacaaattg ttgccaggtt cattcccagc
    27181 ggttgacgtt gcagcttctt atggatttgg ttctccaaat gctgtcttgt caggatttac
    27241 ctttggtttg attggtcaat tgattacaat tgtcttgctc atcgtcttta aaaatccgat
    27301 tcttattatt acaggatttg taccagtgtt ctttgacaat gcagccattg cggtctacgc
    27361 tgataaacgc ggcggatgga aagcggctgt tatcctttcc tttatatcag gtgtccttca
    27421 agttgctcta ggagctcttt gtgtggccct tctcgatttg gcatcttatg gtggctacca
    27481 tggaaatatc gactttgaat tcccatggct tggatttgga tatatcttca aataccttgg
    27541 tattgttggt tatgtacttg tgtgtctctt cttgcttgtt attcctcaac ttcaatttgc
    27601 caaagcaaaa gataaagaga aatattacaa cggtgaagtt caagaagaag cttagtatct
    27661 agaaaaggag aaataaaatg gttaaagtat tagcagcgtg cggaaatgga atgggttcat
    27721 caatggttat caagatgaag gttgaaaatg ctctccgtaa gcttaatcaa acagatttta
    27781 cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc agtaggatat gacatcgtaa
    27841 tcgcttctct tcatttgatt caagaattgg aagggcgaac taatgggaag ttaattggtc
    27901 ttgataactt gatggatgat aaagaaatca ccgaaaaact cagtcaagca ctacagtaaa
    27961 aggttggagg gggctggaca gaaactgaga gttatcgttt ctgtccttct ccctctttaa
    28021 ataaaggagg cagatatgaa tttaaaacaa gctttaattg acaatgactc gatccgacta
    28081 ggtttagagg ctaacaattg gaaagaagca gtcaaggtag cagtagatcc cctaattgaa
    28141 agtggggcaa ttttgccaga gtattacgat gctatcattg aatcgactga agagtatggg
    28201 ccttactata tcttgatgcc aggtatggct atgccccacg ctagacctga agctggtgtg
    28261 caaagtgatg ccttttcatt gattacctta caaaatcctg ttgtattttc agatgggaaa
    28321 gaggtatctg ttttgttggc actagcagca acaagttcaa aaattcacac aagtgtagcc
    28381 attccacaaa ttattgccct gtttgaatta gaagattcta ttgcacgttt acaggcttgc
    28441 cagactaaag aagatgtctt ggctatgatt gaagaatcta aggatagccc ttatctcgaa
    28501 ggattggatt tggaaagtta gaaagaggaa taaagaaatg acaaaaagaa tacctaattt
    28561 acaagttgca ttagaccatt cagacttgca aggagcgatt aaagcagctg tttctgttgg
    28621 tcaggaagta gatattatcg aagctggaac tgtttgcttg cttcaagttg gaagtgaact
    28681 ggctgaagtc ttgcgtagcc ttttcccaga taagattatt gtggcagaca caaaatgtgc
    28741 tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt ggagcagact ggatgacttg
    28801 tatctgttgt gcaaccatcc ctactatgga agcagctcta aaggctatca agactgaacg
    28861 aggagaacga ggcgaaatcc agatcgagct ttatggcgat tggacttttg aacaagctca
    28921 gctttggcta gatgcaggta tctcacaagc tatttatcac caatctcgtg atgctcttct
    28981 tgctggtgaa acttggggtg aaaaagacct taataaggtt aaaaaactca ttgacatggg
    29041 cttccgtgta tctgtaacag gtggtctaga tgtagatact ctcaaactct ttgaaggtgt
    29101 tgatgtcttt acctttatcg caggtcgtgg aattacagag gctgcggatc cagcaggagc
    29161 agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg taaatcatgg tacgtccaat
    29221 tggaatttat gaaaaggcaa ccccaacaca ctttacttgg ctagaacgtt taaattttgc
    29281 caaggagtta ggctttgatt ttgtcgagat gtctattgac gaacgtgacg agcgtttagc
    29341 aagacttgac tggagtaagg aagaacgctt ggaagttgtc aaagcaatct atgaaactgg
    29401 tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc tacccattgg gttcaaaaga
    29461 tccagttcta gaggaaaaat ctctagaact catgaaaaaa tgtatcgaat tagctcaaga
    29521 cttgggagtt cgtacgattc aattagctgg ttacgatgtt tactatgagg aaaagtcacc
    29581 ccagacacgc caacgtttta tcaaaaattt gagaaaagcc tgtgactggg ctgaagaagc
    29641 tcaggtggta cttgctattg aaattatgga tgatcctttc atcagtagca tcgaaaaata
    29701 tttggctata gaaaaagaga ttgactctcc cttcctcttt gtatatccag atattggtaa
    29761 tgtgtctgca tggcataatg atatctatag tgagttttat cttggtcatc atgccatcgc
    29821 agctctccat ctcaaggata cttatgcagt gacagaaagt tcaaagggcc agttccgaga
    29881 tgtacctttc gggcaaggtt gtgtcaaatg ggaagaagct ttcgatattt taaaggaaac
    29941 caattataat ggacctttcc taatcgaaat gtggtctgaa aattgtgaaa cagtagaaga
    30001 aacacgcgca gccgttcaag aggcgcaagc ttttctctat ccactcatta agaaagcagg
    30061 tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa acgagtctgt gatgccaatc
    30121 aatcattgcc aaaacatgga cttgtcaaat ttacctgggg gaatgtatct gaagttaatc
    30181 gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga ttatgacgaa ttgacacctg
    30241 aaaacatggt agtgactgat ctagatggta agatcctaga aggggattta agaccatctt
    30301 ccgacctccc aactcatgtg caattatata aggcttggtc agaaattggt agtgtggttc
    30361 acacccattc gacagaagct gttggttggg ctcaggcagg tcgtgatatt cctttctacg
    30421 gaacaaccca tgcagattat ttctacggtt caatcccttg cgcccgtagt ttgaccaagg
    30481 acgaagtaga agtggcctat gaaaaagata ctggcctggt tatcgtagaa gagtttgaac
    30541 atcgcggact taacccggtt gaagtaccag gaattgttgt acgcaatcac ggtccattca
    30601 cctggggcaa aaatccagag aatgctgttt atcactctgt cgtactagag gaagtatcaa
    30661 agatgaatcg ctttacagaa caaatcaatc caagagttgg acctgctccc cagtacatac
    30721 tagaaaaaca ctaccaacgt aaacatggac caaatgctta ttatggtcaa aagtaagaac
    30781 gatgaaggag gagaaaaaga taaatttagc tcctcttttt acatttgatt tttattgaga
    30841 gtaaagttgg aattgaagta attttaaaag attttttaga aatagcgctt gatatatata
    30901 tggtaaaata aaaagaattg ctgtgatatc aatagatttg ggggattttt taatatggta
    30961 ctggataagg caagttgtga tttgcttcaa tatttgatgg atcaagaaac gtccaaaacg
    31021 attatggcga tttcgaaaga tttgaaagag tcaagaagga aaatttatta tcacattgac
    31081 aaaatcaatg ctgctctggg tgacgaggcg cttcacatca ttagtattcc acgaattggt
    31141 attcacttaa cggaagagca gagagatgct tgttgtaaac tattatcgga agtagattcg
    31201 tacgattata tcatgagtgc gcatgaacgt atgatgataa tgttactatg gataggtatt
    31261 tctaaagaac gtattacgat tgaaaaattg atagagttaa cagaggtatc taggaatact
    31321 gttctcaatg atttgaatag tattcgttat caactaactt tggaacaata tcaggtgatc
    31381 ttgcaagtga gcaagtcaca gggataccac cttcatgccc accctcttaa taaaattcag
    31441 tatcttcaat cgcttctata tcatattttt atggaagaaa atgccacttt tgtatctatt
    31501 ttagaagata agatgaaaga gaggttagat gatgagtgtt tgctttctgt tgaaatgaac
    31561 caatttttta aggaacaggt tcctttagtt gaacaagatt tagggaagaa aataaaccat
    31621 catgaaataa cttttatgtt gcaggttcta ccttatttgc tgttaagctg tcataatgtt
    31681 gaacagtatc aagaaagaca tcaggatata gagaaagaat tttctttgat aagaaaaaga
    31741 atagagtatc aggtgtctaa gaaattagga gaacggttgt ttcaaaagtt tgaaatttct
    31801 ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc tctcctatcg taaagatttg
    31861 gatattcatg cagaaagtga tgattttcgg caattaaaac ttgctttaga agaatttatc
    31921 tggtattttg aatcacaaat ccgaatggag attgagaaca aggatgattt gttacgaaat
    31981 ttgatgatcc actgtaaagc cttgttattt agaaagactt acggtatttt ttctaaaaat
    32041 cctctaacaa aacaaattcg atccaagtat ggagaattat ttttagtcac tagaaaatct
    32101 gcggaaattt tagaaggagc atggtttatt cggctaacag acgatgatat tgcctatttg
    32161 acgattcata ttggaggatt tttaaaatat acaccatcgt ctcaaaaaaa tatgaaaaaa
    32221 gtttatctcg tttgtgatga aggtgttgcg gtttcgagac ttttgctgaa acaatgcaaa
    32281 ctttattttc caaatgagca aattgacact gtatttacaa cagaacaatt taagagtgtg
    32341 gaagatattg cacaagttga tgtagtgatt actactaatg atgatttgga tagcagattt
    32401 ccgattttaa gggttaatcc tatccttgaa gcagaagata ttttgaaaat gctagactat
    32461 cttaaacaca atatatttcg taataagagc aaaagtttca gtgaaaatct ttctagtctt
    32521 atttcgtctt atattgtaga tagcaagttg gctagtaagt tccaagaaga ggttcaaaca
    32581 cttataaatc aagaaatagt agttcaagct tttttggaag atatttgaag gacagtccaa
    32641 tgatgaacac aaacctgtgt ttttcttggt cttttttagt gttttgaagg gtggtatact
    32701 aatctcaaag ataacaatta tatccaaagg aggcaacata tgccaaacgt caaagaaatt
    32761 acaagagagt catggatttt agccactttc ccagagtggg gaacatggtt gaacgaagaa
    32821 atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt ggtggctagg caactgtggt
    32881 acttggatta agacaccagc tggtgctaac gttgtcatgg acctttggtc aaaccgtgga
    32941 aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc aaatggcaaa tatggcaggt
    33001 gttcgtaagt tgcaaccaaa cttgcgtgtt cagccaatgg ttatcgatcc atttgctatc
    33061 aacgaactag actattactt agtttcacac ttccacagtg atcatatcga cccatacaca
    33121 gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta agtttatcgg tccttaccac
    33181 tgtggacgaa tctgggaagg atggggtgtt ccaaaagaac gtatcatcgt tgttaaacca
    33241 ggtgacacta tcgaattaaa agatatgaag attcatgcag tagaatcatt tgaccgtact
    33301 tgcttggtaa ctctcccagt gaacggtgct gatgagacag gcggtgaact tgctggcttg
    33361 gctgttacag atgaagaaat ggctcaaaag gctgttaact atatctttga aacaccaggt
    33421 ggaaccatct atcatggtgc agattctcac ttctcaaact attttgcaaa acatggtaaa
    33481 gactttaaaa ttgatgttgc tttgaataac tatggtgaaa atccggtagg tatccaagac
    33541 aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc tgcgtaccaa agtcattatc
    33601 ccagttcact atgatatctg gtctaacttc atggcttcta ctaatgagat tctagaactt
    33661 tggaaaatgc gaaaagatcg cttgcaatac gatttccatc catttatctg ggaagttggc
    33721 ggtaagtaca cttatcctca agatcaacac ttagtagaat accatcatcc acgtggtttt
    33781 gatgattgtt ttgaacaaga ctctaacatt caatttaaag ctttgctata atataaaaat
    33841 attctttgga ggttatccgt atgttgcatg atacggataa ttttcatata atagtaaaat
    33901 agaatgtgtg attcaataat cacctcaaat agaaaggaaa ttctatgtca aatctatctg
    33961 ttaatgcaat tcgttttcta ggtattgacg ccattaataa agccaactca ggtcatccag
    34021 gtgtggttat gggagcggct ccgatggctt acagcctctt tacaaaacaa cttcatatca
    34081 atccagctca accaaactgg attaaccgcg accgctttat tctttcagca ggtcatggtt
    34141 caatgctcct ttatgctctt cttcaccttt ctggttttga agatgtcagc atggatgaga
    34201 ttaagagttt ccgtcaatgg ggttcaaaaa caccaggtca cccagaattt ggtcatacgg
    34261 cagggattga tgctacgaca ggtcctctag ggcaagggat ttcaactgct actggttttg
    34321 cccaagcaga acgtttcttg gcagccaaat ataaccgtga aggctacaat atctttgacc
    34381 actatactta cgttatctgt ggagacggag acttgatgga aggtgtctca agcgaggcag
    34441 cttcatacgc aggtttgcaa aaacttgata agttggttgt tctttatgat tcaaatgata
    34501 tcaacttgga tggtgagaca aaggattcct ttacagaaag tgttcgtgac cgttacaatg
    34561 cctacggttg gcatactgcc ttggttgaaa atggaacaga cttggaagcc atccatgctg
    34621 ctatcgaaac agcaaaagct tcaggcaagc catctttgat tgaagtgaag acggttattg
    34681 gatacggttc tccaaacaaa caaggaacta atgctgtaca cggcgcccct cttggagcag
    34741 atgaaactgc atcaactcgt caagccctcg gttgggacta cgaaccattt gaaattccag
    34801 aacaagtata tgctgatttc aaagaacatg ttgcagaccg tggcgcatca gcttatcaag
    34861 cttggactaa attagttgca gattataaag aagctcatcc agaactggct gcagaagtag
    34921 aagccatcat cgacggacgt gatccagtcg aagtgactcc agcagacttc ccagctttag
    34981 aaaatggttt ttctcaagca actcgtaatt caagtcaaga tgccttgaat gttgtggcag
    35041 ctaaattacc aaccttccta ggtggatcag ctgaccttgc tcactcaaac atgacttata
    35101 tcaagacgga tggacttcaa gacgatacca atcgcttgaa tcgtaacatt cagtttggtg
    35161 ttcgtgaatt tgcaatggga acaatcttga acgggatggc ccttcatggt ggacttcgtg
    35221 tatacggtgg aactttcttc gtcttctctg actatgtgaa ggcagctgtc cgtttgtcag
    35281 ccttacaagg acttcctgtg acttatgtct ttacccatga ttcaatcgca gttggggaag
    35341 atggtccgac tcacgaacca gttgagcatt tagcaggtct tcgtgctatg ccaaatctaa
    35401 atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc ttggtacctt gcagtgacaa
    35461 gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa cttgactgtt gaagatggaa
    35521 cagacttcga caaggttgct aaaggtgctt atgttgtata tgaaaatgca gccgactttg
    35581 ataccatctt gattgcgaca ggttcagagg ttaatcttgc tgtctcagct gctaaagaat
    35641 tggctagtca aggcgaaaaa atccgcgtag tcagcatgcc atctacagat gtctttgata
    35701 aacaagatgc agcttacaag gaagaaattc ttccaaatgc agtccgccgt cgtgttgcag
    35761 tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg tctcgatggt gccgttctag
    35821 gtattgatac cttcggagcc tctgccccag caccaaaagt attggcagaa tatggcttta
    35881 ctgtcgaaaa tcttgtaaaa gttgttcgaa atttgaaata atcctaaaaa tcagggcgta
    35941 agctctggtt tttcttacca gaaaagtaag gtacaatctt gtaaaagtag ctgaaatttg
    36001 atatagtagt cctatgtaaa agacaaagga gaaaacaatg aatccaaata ttactttttt
    36061 aatcatgctt gtaggtatga tggccttgat gttctttatg caacgttctc aaaagaaaca
    36121 agctcaaaag cgtatggaaa gcttaaataa actacaaaaa ggctatgaag tgattacaat
    36181 cggtggactt tatggaacag tcgatgaagt agatacggag aagggaacaa tagttcttga
    36241 cgtagatgga gtttacttga cttttgaact agctgctatc aagacagtat taccgctgaa
    36301 agaaacagct tcactagaag gcgcaattga aaaataagac gggatcacga actcccgttt
    36361 tctataaaag aaaggaaatg ggatgaaaaa attagtcttt gtctgtctgg gaaatatttg
    36421 ccgtagccct atggccgagt ttgttatgaa atcaatgaca gataactacg aaatccaaag
    36481 tcgagcaact tcctcttggg aacatggcaa tccgattcat aaggggactc agggaatttt
    36541 tcaagagtat gagattcctt atgacaagaa caagacatcg cttcagatta gtaaggaaga
    36601 ttttgaagcc tttgattata ttatcggaat ggacgcttca aatatttctg acttacgtca
    36661 gatgtgtcca gtagactgtc aagataagat ttactcattt tcatctgaaa gtgttccaga
    36721 cccttggtat acaggagatt ttgaagaaac ctatcgacgt gttcaagagg gctgtcaagc
    36781 ttggttagaa cgtttagaaa aggagagtta aggtggaaaa tcttacgaat ttttacgaaa
    36841 agtatcgtgt ctatctgact cgtccacgtt tagagctttt ggcagtagtt accattgttt
    36901 tctgtgctgt actcgtcttt tttctaaata ttccaggaaa aggtgtctta aaactcgata
    36961 atggaacgat tgtttatgat ggcagtcttg tccgtggtaa aatgaatggc caaggtacca
    37021 ttaccttcca aaatggagac caatatacag gtggcttcaa caatggagcc ttcaacggaa
    37081 aaggtacctt tcaatctaaa gaaggctgga cctacgaagg tgattttgta aatggtcagg
    37141 ctgaaggaaa agggaaacta acaacagaac aagaagtcgt ttatgaagga acttttaaac
    37201 aaggcgtttt tcaacaaaaa taaagcctcc tatcaaagga ggtattatta gaatcacaag
    37261 gtaagcgctt acctgtgaat ccctttcttt ccaaatccct cttccaagca agtttgtgaa
    37321 ataaaaaata tttgaaataa atttcacaaa cttcaaagat aaaacttgat aagaaaagaa
    37381 aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga aatgtttatg aaactgttta
    37441 caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa ttaacaaagg atatcgttcc
    37501 ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg tgacaccaga ggaaaagaaa
    37561 ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag ctctagttgc ccttgaagaa
    37621 atgcgtaaat tggatcaaga acaagttgac tacatcgttg ccaaagcatc agtagcagct
    37681 ttggatgccc acggagaatt ggctttacat gcctttgaag aaacaggacg tggtgtattt
    37741 gaagacaaag caactaagaa cttgtttgct tgtgaacacg tagtaaacaa catgcgccac
    37801 actaagacag ttggcgttat cgaagaagac gatgtaacag gattgactct tattgctgaa
    37861 ccagttggtg ttgtttgtgg tattactcca acaacaaacc caacatcaac agcaatcttc
    37921 aaatcattga tttcattgaa gacacgtaac ccaatcgtct ttgccttcca tccatcagca
    37981 caagaatcat ctgctcatgc agctcgtatc gtccgcgatg cagctatcgc agctggtgct
    38041 cctgaaaact gtgtacagtg gatcactcaa ccatctatgg aagcaactag tgcccttatg
    38101 aaccacgaag gtattgcaac aatccttgca acaggtggta atgccatggt taaagccgca
    38161 tactcatgtg gtaaaccagc tcttggggta ggtgccggaa acgttccagc ttatgttgaa
    38221 aaatcagcaa acattcgtca agcagcacac gatatcgtca tgtctaaatc atttgataac
    38281 ggtatggtct gtgcatctga acaagcagtt atcattgata aagaaattta cgatgaattt
    38341 gtagcagagt tcaaatctta ccacacttac tttgtaaaca aaaaagaaaa agctcttctt
    38401 gaagagttct gcttcggcgt caaagcaaac agcaaaaact gtgctggtgc aaaattgaac
    38461 gctgacatcg ttggtaaacc agcaacttgg attgcagaac aagcaggatt tacagttcca
    38521 gaaggaacaa acattcttgc tgcagaatgt aaagaagttg gcgaaaatga gccattgact
    38581 cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg aaagccgtga agatggtatt
    38641 actaaggctc gtcaaatggt tgaatttaac ggtcttggac actcagcagc tatccacaca
    38701 gctgacgaag aattgactaa agaatttggt aaagctgtta aagctattcg tgttatctgt
    38761 aactcacctt ctacttttgg tggtatcggg gacgtttaca atgccttctt gccatcattg
    38821 acacttggat gtggttctta cggacgcaac tcagttgggg ataacgttag tgccattaac
    38881 ctcttgaata tcaaaaaagt cggaagacgg agaaataaca tgcaatggat gaaacttcct
    38941 tcaaaaacat actttgaacg tgattcaatt caataccttc aaaaatgtcg tgacgttgaa
    39001 cgtgtcatga tcgttactga ccatgccatg gtagagcttg gtttccttga tcgtatcatc
    39061 gaacaactgg accttcgtcg caataaggtt gtttaccaaa tctttgcgga tgtagaaccg
    39121 gatccagata tcacaactgt aaaccgtggt actgagatta tgcgtgcctt caaaccagat
    39181 accatcatcg cactcggtgg tgggtctcca atggatgctg ccaaagtaat gtggctcttc
    39241 tacgagcaac cagaagtgga cttccgtgac cttgtccaaa aattcatgga tatccgtaaa
    39301 cgtgccttca agttcccatt gcttggtaag aagactaaat tcatcgcgat tccaactaca
    39361 tctggtacag gatctgaagt aacaccattt gccgttatct ctgataaagc aaacaaccgt
    39421 aaatacccaa tcgctgacta ctcattgaca ccaactgtgg caatcgtaga tcctgctttg
    39481 gtattgacag ttccaggatt tgttgctgct gatactggta tggacgtatt gactcacgcg
    39541 acagaagcat acgtatcaca aatggctagt gactacactg atggtttagc acttcaagcc
    39601 attaaattgg tctttgaaaa tctcgaaagc tcagttaaga atgcagactt ccactcacgt
    39661 gagaaaatgc ataacgcttc aacaatcgct ggtatggcct ttgccaatgc cttcctaggt
    39721 atttctcact caatggccca taagattggt gcgcaattcc acacaatcca cggtcgtaca
    39781 aatgctatct tgcttccata cgttatccgt tacaacggta cacgtccagc taagacagca
    39841 acatggccta agtacaacta ctaccgtgca gatgaaaaat accaagatat cgcacgcatg
    39901 cttggacttc cagcttctac tccagaagaa ggggttgaat cttacgcaaa agctgtctac
    39961 gaactcggtg aacgtattgg gatccaaatg aattttagag accaaggaat tgacgaaaaa
    40021 gaatggaaag aacattctcg tgaattagcc ttcctggctt atgaagacca atgttcacca
    40081 gctaacccac gtcttccaat ggtagaccat atgcaagaaa tcatcgaaga tgcatactat
    40141 ggctacaaag aaagaccagg acgccgtaaa taattgttta tcagtctaga agcaagacaa
    40201 aaactcaatt tgagggaaag atccagtact ttttctatga taaaaggcat cctatcaagg
    40261 tttttgaaca cctgatagga tgccttttta tgatattgag gcctttttgc cctttttgaa
    40321 aaactagaat agaaacaaaa tatataatag attgaaactg gaatagtaca cttctgcttc
    40381 taaaacattg ttagaattcg atttgactgt cctgatcgat ttgtcctgtt cttatttcat
    40441 tttaatatat aaaaaatat
//
LOCUS       DAVBOH010000015        40389 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOH010000015 DAVBOH010000000
VERSION     DAVBOH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.015"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..262)
                     /locus_tag="VQ873_000864"
     CDS             complement(<1..262)
                     /locus_tag="VQ873_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107152.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGA"
     gene            complement(705..1160)
                     /locus_tag="VQ873_000865"
     CDS             complement(705..1160)
                     /locus_tag="VQ873_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107153.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1435..3172)
                     /locus_tag="VQ873_000866"
                     /pseudo
     CDS             complement(1435..3172)
                     /locus_tag="VQ873_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(3335..4219)
                     /locus_tag="VQ873_000867"
     CDS             complement(3335..4219)
                     /locus_tag="VQ873_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3107154.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(4331..5185)
                     /locus_tag="VQ873_000868"
     CDS             complement(4331..5185)
                     /locus_tag="VQ873_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3107155.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSENREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(5243..6001)
                     /locus_tag="VQ873_000869"
     CDS             complement(5243..6001)
                     /locus_tag="VQ873_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3107156.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(6063..6251)
                     /locus_tag="VQ873_000870"
     CDS             complement(6063..6251)
                     /locus_tag="VQ873_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3107157.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(6574..7140)
                     /locus_tag="VQ873_000871"
     CDS             complement(6574..7140)
                     /locus_tag="VQ873_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107158.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(7408..9087)
                     /locus_tag="VQ873_000872"
                     /pseudo
     CDS             complement(7408..9087)
                     /locus_tag="VQ873_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(9179..9340)
                     /locus_tag="VQ873_000873"
     CDS             complement(9179..9340)
                     /locus_tag="VQ873_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107159.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(10024..10338)
                     /locus_tag="VQ873_000874"
     CDS             complement(10024..10338)
                     /locus_tag="VQ873_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107160.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(10304..10693)
                     /locus_tag="VQ873_000875"
     CDS             complement(10304..10693)
                     /locus_tag="VQ873_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3107161.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(11081..11875)
                     /locus_tag="VQ873_000876"
     CDS             complement(11081..11875)
                     /locus_tag="VQ873_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107162.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(11875..12882)
                     /locus_tag="VQ873_000877"
     CDS             complement(11875..12882)
                     /locus_tag="VQ873_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3107163.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(12882..13889)
                     /locus_tag="VQ873_000878"
     CDS             complement(12882..13889)
                     /locus_tag="VQ873_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3107164.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(13879..14904)
                     /locus_tag="VQ873_000879"
     CDS             complement(13879..14904)
                     /locus_tag="VQ873_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3107165.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(15297..15515)
                     /locus_tag="VQ873_000880"
     CDS             complement(15297..15515)
                     /locus_tag="VQ873_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107166.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(15761..16039)
                     /locus_tag="VQ873_000881"
     CDS             complement(15761..16039)
                     /locus_tag="VQ873_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107167.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(16253..17884)
                     /gene="rlmD"
                     /locus_tag="VQ873_000882"
     CDS             complement(16253..17884)
                     /gene="rlmD"
                     /locus_tag="VQ873_000882"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3107168.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRGLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(17958..18932)
                     /locus_tag="VQ873_000883"
     CDS             complement(17958..18932)
                     /locus_tag="VQ873_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3107169.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGSNFLSSLWQALVNFFKSFGS"
     gene            complement(19006..19620)
                     /gene="pmp23"
                     /locus_tag="VQ873_000884"
     CDS             complement(19006..19620)
                     /gene="pmp23"
                     /locus_tag="VQ873_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3107170.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(19620..20594)
                     /locus_tag="VQ873_000885"
     CDS             complement(19620..20594)
                     /locus_tag="VQ873_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3107171.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(20602..21858)
                     /locus_tag="VQ873_000886"
     CDS             complement(20602..21858)
                     /locus_tag="VQ873_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3107172.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(21920..22351)
                     /locus_tag="VQ873_000887"
     CDS             complement(21920..22351)
                     /locus_tag="VQ873_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107173.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(22353..22952)
                     /locus_tag="VQ873_000888"
     CDS             complement(22353..22952)
                     /locus_tag="VQ873_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3107174.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(22939..23778)
                     /gene="prmC"
                     /locus_tag="VQ873_000889"
     CDS             complement(22939..23778)
                     /gene="prmC"
                     /locus_tag="VQ873_000889"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3107175.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(23778..24857)
                     /gene="prfA"
                     /locus_tag="VQ873_000890"
     CDS             complement(23778..24857)
                     /gene="prfA"
                     /locus_tag="VQ873_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3107176.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(24867..25346)
                     /locus_tag="VQ873_000891"
     CDS             complement(24867..25346)
                     /locus_tag="VQ873_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107177.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(25336..25935)
                     /locus_tag="VQ873_000892"
     CDS             complement(25336..25935)
                     /locus_tag="VQ873_000892"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3107178.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            26058..26240
                     /locus_tag="VQ873_000893"
     CDS             26058..26240
                     /locus_tag="VQ873_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3107179.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            26377..27750
                     /gene="mnmE"
                     /locus_tag="VQ873_000894"
     CDS             26377..27750
                     /gene="mnmE"
                     /locus_tag="VQ873_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3107180.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(27797..28732)
                     /gene="dapA"
                     /locus_tag="VQ873_000895"
     CDS             complement(27797..28732)
                     /gene="dapA"
                     /locus_tag="VQ873_000895"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3107181.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(28788..29864)
                     /locus_tag="VQ873_000896"
     CDS             complement(28788..29864)
                     /locus_tag="VQ873_000896"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3107182.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(30206..30278)
                     /locus_tag="VQ873_000897"
     tRNA            complement(30206..30278)
                     /locus_tag="VQ873_000897"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30243..30245),aa:Thr,seq:ggt)
     gene            complement(30378..30887)
                     /locus_tag="VQ873_000898"
     CDS             complement(30378..30887)
                     /locus_tag="VQ873_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3107183.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(30885..30981)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            31010..31441
                     /locus_tag="VQ873_000899"
     CDS             31010..31441
                     /locus_tag="VQ873_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3107184.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            31523..31900
                     /gene="mscL"
                     /locus_tag="VQ873_000900"
     CDS             31523..31900
                     /gene="mscL"
                     /locus_tag="VQ873_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3107185.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(31942..32915)
                     /locus_tag="VQ873_000901"
                     /pseudo
     CDS             complement(31942..32915)
                     /locus_tag="VQ873_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
     gene            33070..34293
                     /gene="pepT"
                     /locus_tag="VQ873_000902"
     CDS             33070..34293
                     /gene="pepT"
                     /locus_tag="VQ873_000902"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3107186.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34329..34958)
                     /locus_tag="VQ873_000903"
     CDS             complement(34329..34958)
                     /locus_tag="VQ873_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107187.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            34923..35144
                     /locus_tag="VQ873_000904"
     CDS             34923..35144
                     /locus_tag="VQ873_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107188.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(35415..36426)
                     /locus_tag="VQ873_000905"
                     /pseudo
     CDS             complement(35415..36426)
                     /locus_tag="VQ873_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36652..39771)
                     /gene="phtE"
                     /locus_tag="VQ873_000906"
     CDS             complement(36652..39771)
                     /gene="phtE"
                     /locus_tag="VQ873_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3107189.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(39982..>40389)
                     /locus_tag="VQ873_000907"
     CDS             complement(39982..>40389)
                     /locus_tag="VQ873_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET3107190.1"
                     /translation="KPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPS
                     TDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLK
                     SSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        11842 a         8156 c         6666 g        13725 t
ORIGIN      
        1 tagcacctct ttctttcaca atttcaattt tcaaagtcaa ttcataatct tcaacaggat
       61 tgagcatttt atcttctcct acaatatcga cataagatac attaaacttc tgacaaatga
      121 tgtcaattaa ttccgtagag actgaactag ttccattttc ataacgactc aagctatttc
      181 gagaaattcc tataattcgt gcaaattcag gttgtgttaa gtcatgtgtt ttacgtaagg
      241 attttatgtt ctttccaatc atagtaaact cctttatttt tataattcaa ttatagcata
      301 aaaaagtata acgcaccaat tttggtgcgt tatacttttt ttctagccta aactttactt
      361 ctataaaagt cacctaaaga gccataaata tttattcttg tattaatttt ttcgatgcgc
      421 aaacgatatc tacaaataca tctataacga ttcacctttt aggattttta ttgtcaaaat
      481 tgcctttatc tacaaagaca aaatgcttat aaaatagctt gaaatcaagg attatcacct
      541 ttttcgttgt agcaacactc cacatgtgat tattaggcta ttagcaaagc gtatccaata
      601 cctcaataaa gtgttgtttt tactgatatt ttaactatat tgtatagtct actatttaaa
      661 tctcaattag gatattttat agaataccca aaattcaaca ataactaaaa gtaagattcc
      721 attgtatttc cttgttggtc tttcatatca cgaattttat ttttcagaat attaaagtta
      781 caaatttcat ctctaatatc gttatccgct ctgtagccat taatcatctc agtcagagtt
      841 ttccctttac taccattctt tatagtagta tttactcttt ttatactgct ttcaaaaggc
      901 tcatatgttt tatacttaat tacttcgtct ttaaaattaa ataaaggtgt atccggctta
      961 gcattccata aaataatcaa ccacattata gcattataaa gctgctttgc agtttcattc
     1021 cacttttcag gttgtaaatt tccactccct gtattgtcat attcttgtct attatttaca
     1081 tgagaatcac ctacaagtgg attaaaaaga ggtagccctt tgtgattaat tagttctaaa
     1141 aaatcccttg ccgcacccat gcaacactga ataacttcct tcttgccatc aattttactc
     1201 tcagcgataa atacataata ttcatcttca atagttgctc ctgcatcact atgtttttgt
     1261 tgatttgcta acagcttaat atgtgcttta ggctaaactt caaaatctct aacaattctt
     1321 tgtcttgttt catgtcctct acaattcatt taagttctcc tttacaagtt tagtaactag
     1381 ccttattata ctatataaga tatgaaatgt accataatct tcatcaacta gtttttagaa
     1441 aatcacaaat ccatctggag agatgacaag ctgattctcc aattcttggc aattgcttgc
     1501 tagtgctact gcttctttct ctaaaagata atcttctgtt gattggttga atattgcttt
     1561 gaggatccgt ccttcgtatt tccattccag agctactaaa tcagatttga tttcttgaag
     1621 gctatacttg ccatgcgaaa taattactga cgcgtatttc cgaatcttaa tcagcctctt
     1681 cataaagttc agcatatcat tgtcacttga tacacgttcc caaggcatac aacgacgaca
     1741 atctggatct ggtcctccag tcaaggctag ctcggttccg taataaatgc acggtgttcc
     1801 tttttgtaaa aagagaaagg ctaaggctga tttaaccagt tgaacatctt cattggccgt
     1861 ccacaggatt cgctctgtat catgtgaatc caagagatta aacatgacct ctgaaatctg
     1921 ctgcttgtaa tacatagact ctccattgat ttcatcgatg aactggtctg tcttcttaat
     1981 tcctcgtaag aaatagtcct tgatactatc agataaagga taattcatga tggcatggaa
     2041 ctcatctcca tttagccaag gctgagatgt atgccagact tctcctagga tataaagatc
     2101 aggattttta gctaaaactg ccttacgaaa atccttccag aactgatggt caatctcatt
     2161 agccacatcc aaacgccaag catcgatatt aaactcttca atccaataag tcgcaacctt
     2221 taaaagataa ttcttgacct ctggattggc tgtatttagc ttaggcatat agtcctcgaa
     2281 accaaaaaca tgatagggta agtctctctt attaactagt ttttcagttg tcactgggaa
     2341 ttgttgaata tggaaccaat ccttataagc agactgttca ccatttttga cgacattttt
     2401 ccattgaaga gattgcgaac caatatgatt aaataccgca tccagcatga ctttcatgcc
     2461 acgatgatgc gcttgatcca ccagttcccg aaaggtctcc ttgtctccaa aatgacggtc
     2521 aatttcaaag taatctgtcg tattgtactt gtgattgctt gtagattcaa agatgggaca
     2581 aagatatagt ccagtaatac ccaagtcttg caagtaatcc atatgatcaa taatcccctg
     2641 taaatcacca ccaaagaaat catcgctctt aggtgtgaca gatgaatccc agtctaaagt
     2701 cccttctggg tttaatagag cattgccatt ggcaaatctt tcaggaaata tctgatacca
     2761 taccgtattt gaaacccagt caggaacctt gcaggcatca atcttgaaga taaggcaact
     2821 taaatccatt cccaattgca tgaagatttt ctagagaatt ttccacacac cctttatcgc
     2881 catacaaaat attttgacct tctgtatctc tgagctcaaa gagatactgg atacgtgcaa
     2941 agtcaactga cacttcaacc tgccaatggt caaataaggt accagaagtt atcttgacca
     3001 tttcttttgt atcctgataa aactcctcca taaagataaa agggtcccca tagtgcaagt
     3061 tgatgctttc aatgtcccct ttcttagttc gaattcgaat atggagtttc ttatccttat
     3121 aaagataggc atactccgac tcaggcctat ggtaaatagc actcaattcc atcaatttgt
     3181 ctcctaaagt attcattcaa attttacgca aacgttttca aactcaatga atccagtata
     3241 ctatttttgt aaactatttg caaggaatgt ccgttgttaa aggaactatc ttttaaagta
     3301 tacaaaaagc cttaaaaaag gctttctcta tatactaatc ctctttcggt tttgaaaata
     3361 cttctactcg ctgagctagg actttgattt ctacaggtag gttatctgat ttatctccgt
     3421 caacatctga ctccaattca ctatctgaag agattttaat attacgcgct ttgatatact
     3481 cgatattatc atttgcgaca acatcccctt ttaataaatc aggaatgacg gataatttgg
     3541 agaatataga ggcatctttc agaatcaaaa tgttggcata gccgtccttg ttttcttcaa
     3601 agattttctt atcagcgaag taatttgtca aaaggaccaa aacatggcta gcttcaccaa
     3661 cataatttcc attttctgtc tcaaccttaa tgttaaagac ctgatctgtc atgacagact
     3721 tcatggtatt tacagcatag gttaaaatac cgaattttgt tttgtcctct atttcaacat
     3781 tgtgaatcgc ctcaggcaga gaaccgatac taaagatata accaaaatag ttgtcatttg
     3841 ctttaccgat atcaatctta ttgattaaat caaaatccag ttcgtcaatt gcgccatcga
     3901 tgtcttgatt gatttccaaa agttttgtaa tgaggttacc cgtaccgcct gggataatcc
     3961 ctaacttagg aatgtagtct ctctcatcaa tacctgaaat gacttcattg acagttccat
     4021 ctccaccaaa cacaaccact gcatcatact gctcacgaga agcttcttca gcaaaatgtg
     4081 ttgcatccag cgctttttcg gtaattttgg tttcaacata ttcaaagtat tcttttgctt
     4141 tattctccag cttttctttg taatccaaag ccttctcgcc accagaagta gggttgataa
     4201 ttaccattgc ttttttcatt gattttatcc ttaattttaa acagaaatgt ttacatttcg
     4261 tcgtatgcaa gtaaatgtaa tcctattata caatgaaaat acagaaaaga gaaatctgac
     4321 atactggaga ttaatacgct tttattctat tttcccatcg cctaactaca tcctttaagg
     4381 gttcatccaa gtaagaatag gccttatcct tgatccaatc aggaataccg taagctgcct
     4441 ctgctatgct acaagtgatt gctgcgagag tatcactgtc gccaccaagt gagatggcat
     4501 ttcttatcgc atcttcgaag tctctacttt caagaaaggc gataatggct tgagggacag
     4561 tttcctgaca tgtttcgtta aaacgatagt taggacggat ttcatctaaa gtttgagata
     4621 gattgtaatc gtattctttt tctatataat ccttaattcg tcttttacac tctgtaggat
     4681 tgtcgttaat tgattgctcg tactctctac aataaccacc aaagtaaaaa cgacatagaa
     4741 agatagcatc agctgtagcc atagcgcctt tgacaccttc tggatgatta tgagttacct
     4801 ctgcagaaag actcgtaagt cctctagatg atggccacat accagttttc gcataaaaac
     4861 cacagtccat gatccaagca catggagaaa tacgcatagc tgatccattc ccaaagctat
     4921 tataaggctc acggttttcg ctgtttagcc atgcattaaa ccgagcaccg taatcagcat
     4981 tcggatacat tctgccatat ttcttcatcg cgtcaatgaa atcgtctttt tgtccaccat
     5041 tcataattgc ttctgcaaca gcacaggtca taaccgtgtc atctgtaaaa aagcagtcct
     5101 tccgaaataa aggaaagtcc tttgttttga tattgttcca ttcgtaaaca gaaccgacaa
     5161 tatctccaat aattgctcca agcatcagat tcctccttgt tcattttgat gctttttata
     5221 ttggttatct accatattta ttttagaaaa taacatcctg ttggatttta aaaatttcat
     5281 ttttttcaaa atagggtttt accatttctt tccacctagc tctatgaaaa ttgattgatt
     5341 ttaaaggaga taggccataa tttcccaatg cataaccatc atttacttca acaacaagtg
     5401 ttctgccatc gcgagtaaca ccgatatcta gtccataagc tattggcgca tctttccaac
     5461 atgatatcgc ttcatcaatt acacttgcat caaattgtgc atgataatca cctgtatagg
     5521 gtcgaacatc taatacgcga ccatctaaca caaaacaacg ccattcagct atgaattcta
     5581 caacctcact aatccatata ggatagtcga aaggtagacc aatacctatt aaatcatggg
     5641 ttccattaac aactcttcca gtaaagactt ttgaaccagc tttaggctta ataaattttc
     5701 cccaattatc aggtatattc acaatctctc ctaaaatacc agcataaatc tttcgaccat
     5761 aaaactcttt aagctcaata ggatagtcat gaaccggaac gtttaagccc atcattttta
     5821 gtaatgctct agtctccatt atataatcta caactatatc ttcacttgtt aactctttta
     5881 tttcagaaaa agattgatat aaaataactt cttctccttg taagtaggca cctacttgag
     5941 cattgtattt attaattgaa acctcacttg gtaatttact ttgtctaata taaacaacca
     6001 tttcatcact cctatatcac tagtgttaca ccaatttgta aaaaataata gcaattttgc
     6061 tcttattttt ttgagtaaat agcccccata atatcatcga aataatcaac ggtatttagg
     6121 agtaattcaa taacctggga ctttgttagt cgcattcccc ttctatctct agcatcttct
     6181 actaaatttt caagtttctc tagattttta tcatccaagc taatcattat tctattttta
     6241 tcggttgcca ttttcatcac ctcgagttaa ttctatcaca ggtgtaacac ttgtgtcaac
     6301 tggcttttat aatacattag tttaaaagtg gagaggattt ttaacacagt aactttaaat
     6361 ctttggtatt aaaaaatttt cacaatattt atagaaataa aatctgtctc aaatcagtta
     6421 tcaaatctag tataaattat gagcggctac tctaatactt tccctctaaa caagaaaaag
     6481 acttacactc aagggttttc ttcccccccc ttcgttataa cgttttgact cttttactag
     6541 caaaggtata tactcacaag gaactttggt tgactattga atctctccaa cttcttcttt
     6601 aacatatcct tctacatctt caatctctac aaacattggg tctaagtgac acaagaaatg
     6661 ccaaacttcg atcccttttt ttctgtaaag aatcgcttca ccgtcttcac ttccgaaaaa
     6721 gcttctgtcg atttcatatc cgcggctttc taagaagtct tttgctttac gatagttcgt
     6781 ttctcttgtt tcgacatagg ctttaacttc atggttgtta acgacatatg catcaatttt
     6841 tgaatatcct tcgatcactc tatcattttt gagggataaa tttgaaatct ctttccaaat
     6901 aatgtttaca ttttcctcag gatcgaacat aaatttagat aaaggaacaa tatttccgtt
     6961 aaaaataatt tccatataat ccggtatgtt tttaggatta aaatactcca cttcaaaacc
     7021 atcttctgtt tccagagtgt atcccgggat ttgagctaca aaggctttcc catcttctat
     7081 ggaatcaaat gctactaaat ctttagaata atcattttgg tacaattcca atataaccat
     7141 cgataatctc tccattttca ttatcaggcc aatgtaaata agcacgtcac ctgaccaatt
     7201 caggctctct gtatcatctc atcatatttc ctacttactt tacgagtcct atacccagaa
     7261 cacaccttat cgaccttcgg tctcacctcg tcgcattggc tgaacatcta cttttacttc
     7321 gctgatgctt caactcgtac aagcagtgat accgcctcag cgtgatgcgt cagtgggact
     7381 caaaaagttt ggggaacctt ttgaggatta actacgtttc tctaataaac ttacacattc
     7441 aacttgttca tcattgtcca aatctatgtt gagattttct tctataattg gtagcttaaa
     7501 agtaatggat tttagccatt gtccgttaga ttgtttttct tcataaactt gaatttcaga
     7561 aatcaaagct gaaattaact gcctacgctc tacatcattc atgactttat agagcttatc
     7621 aaaatagatc agaaccttat atatgttatc tcctgtaagc ttttcagctt caatagtctg
     7681 tttctttgct ttcgcatcaa ttagtgatga ttctaattca tctattttgt catacatacg
     7741 atatagtcta tcatctaaat cctgtttcct tctcttataa tgcttatctt caacatctaa
     7801 attatctatt tcctcaatta gcttaaactt tgtagaatga ctctttctca attccttttg
     7861 gtaattatct atttcttttt ctatttcaga ggtatccacc ttcatgttga ttttttcttg
     7921 catcatagaa gcaaatttcg gattacttac tatcttgaca atcacctctg caacagcatc
     7981 atctaacaat tcttctctaa tttgcttact gaatgtacac ttatgacctc ttatcatctg
     8041 cctatggtta caaccatagt aataaaaatc tttatacttt gtgccatctt tctttttctt
     8101 gatacacttg ttcccaaaca ttcccactcc acatatcggg cattttacaa ttccagaaag
     8161 caagtgtgtg cgtgtatctt ttcctttatt cacatgctca tatttctttg cttgagattt
     8221 tagcttaacc tgagcagctt accaaacttc atcggaaact atagcttcat gtatcccttc
     8281 agatattaga tattcatctt gttcaacctg cttatattca tttcttgtac catgaacttt
     8341 ttctaaagtt cttcttccaa atgctatttt cccattatat acaggattct ttaatatctt
     8401 tcttataaga cctgcatcaa acaaaggatt cttaccattc tgtcttggga tttttctaat
     8461 tccatgattc tctaagtatt tagatatccc attggctcct atcgtagtat ttacatactg
     8521 gtcgaaaatc gttcttattg caactgcctc ttcctcattt ataaacagct tgccgtcttc
     8581 aagtttatat ccatacggag caaagccacc attccatttt ccttcccttg ctttttgaat
     8641 gcaaccttcc attgtttgaa tacggatgtt ttctctttct atttcagcca cagctgataa
     8701 aacagaaatc attagtttcc cagcatcttt agatgaatca atgccatctt caacgcagat
     8761 aagattaact ccataatcct gcattatctg aagtgtagaa agaacatcag cggcatttct
     8821 tgcaaatctt gataacttaa acacaagaac aaaagatact ccatcttttc cagattttat
     8881 atcttccatc attcgattga actgtattct accttcaata gacttgccag acttcccggc
     8941 atcttcatac tctccaacaa tttcataatc gttgtaaata gcaaaagctt tcattcgtga
     9001 tttttgtgcc tctaacgaat acccctctat ctgtattgac gtagatactc gtgtatagag
     9061 gtatactttt attttttctt ttgacatagt attaacctca atataatttt tctatatcat
     9121 atataatttt tttaatttaa gtttggacta tcatttcaag tatattataa cacttttatt
     9181 agtccgtctc aatttgtgtt tttgccatgt caaaactatt tttcatctct tgattttttg
     9241 ctggcgttgg atcgggtaga ttatctaaat ctaaagcacc agcatatttt gcaatcagat
     9301 ttgctattaa atcagccaat ccattccagt cattgtccaa tatatacctc ctctaaagtt
     9361 ttatatctaa taattatttg tttaattaag ttttttgaca ttgacaagtg ctttggatta
     9421 gcaacatagg aatctcacct ccgcctctat tccggatgag ccggcttcaa ccttagaagt
     9481 atcattatcc tcattttctt catagcggat agggtatccc tccctatatt caaactctta
     9541 cttatcgctc actttctttt tacttagcag aacttttttt gccgaattat tcagccgaaa
     9601 gatcttgacg gataggttat tacgctccaa aaataattaa cgtcttgtct tggtctattc
     9661 aattgttaag gttcaaaatt tatcgagagt tattaatctt tttaaaattt gaccatcaga
     9721 aaatatttat cttaatgtaa caaaattcta taaattaccc tcttatactt aacagtgaaa
     9781 agaagtcttt cttggtaacc aattttgaaa tagaatttgc ttatataaaa aggtcaaatt
     9841 cccactgcat aagtagcagt gaaaattaga ccctcttggt aactgtcatc taaaagtctt
     9901 ctagcatttc tttaattttc taatcgcctt taaagtgtca tatttatatt tttttatctc
     9961 tggcatactt tgataccttt ttagacttaa agtctttaat agtgcctttc cacctctttt
    10021 tatctataaa gattctccta catcataatt cattttttta tttaaacctt tctgtcttag
    10081 tttgtcttta tcttcttcat accattttaa gattgtcaca tagtggtttt gataggtctt
    10141 accactgctt tccatgtatc tggatagttt atttatcatt atatctgtgt gtgagtttaa
    10201 tttttctttt agatttttat attcttcttt gcttaacctt acatttttga attctccata
    10261 aaaaatgggg gtggactttt tatctatctc tccctctctc tctttatcta tctctatatc
    10321 tttccatgta attccaatct ggagtacctc tactgtctat cggtaattta attttgatat
    10381 ctggcaatac tgtgctagat atttgatctt tatattcagt attttttaaa gcttgcctaa
    10441 taattgaagt taaatagaat gctacttctt tattcaattc tttatttttt aattttaaac
    10501 aatgaatttt catatctagg cttgctttat atttatgata aaagactgct cctaaaaatg
    10561 aaacagatat aaaattttca aaaactctat aatttttatc atctatatct tcgtagtaac
    10621 ctaagatacc attgtcaata tttgtagcac taattctagg agtttttcca tcgagtaaat
    10681 atctttttgg aatagatgag cctgttggta cttgactcga tttccccttt ttttcggtaa
    10741 taaatatttc tttttatttt gttgtccgat atttttccta cctgtccttt gtaggatgag
    10801 tattttctag attttcttga ataacttttt acttgaagtt ttagcttttg aactagtcgt
    10861 tgtactttct ttttgtttat tatcagtcct gatcttttta atattgctgt tattctctat
    10921 atcctatttt tcattcatga tattctttta ctaattttat cttaaattct gtgctgtatt
    10981 tgccattaaa aaactgacct cctttagtta gttttttggc ctaacttttg agggtcagtt
    11041 caaaatttgc gacttttaaa tgaattccga tattcaatta ttaagagcta acatggtgct
    11101 tgccaatagg aatcattaga ggcgaattgg aaatagggtc acgtataatt tttgcttcaa
    11161 gattaaagat atctttaact agtttatcat ttagtatatc ttcaggcttt ccctctgcaa
    11221 caagtttacc ttctttaatt gcaaataggt aatcagcgta tcttgctgtt agatttatat
    11281 cgtgcaaaat catgcaaatg gttgtcttat atttttggtt tagatcagtc aagaggtcta
    11341 atagttctat ttgatatgag atatccaagt aagtagttgg ctcatctaaa agtaggatac
    11401 ttgtatcttg ggctagggct agagctatcc atactctttg cctttgaccc ccagaaagtt
    11461 cttcaactag gttatttgct agatcttcaa cattggcctt aaccattgat ctgtttatta
    11521 tttcaaggtc atcttttcca agactcttaa aaggctttct gtaggggaaa cgaccacggc
    11581 ttacaagatc agctactgtt attgattcag ggattattgg agattgaggt aatatagcta
    11641 tgtgttttgc taaatctttt tctttataag aattaattga tttattatcg agcaatactt
    11701 ctccctctaa tggctttata agtcgagaca aggttttaat gagtgttgat ttcccacaac
    11761 catttgaccc aataataact gatatttttt cttcaggtat ttttatattt atattttcca
    11821 agattatttt ttcatcataa ccgcaggtaa gattatttga ccacagacct ttcattatat
    11881 attcctcctg ttcattttta ttagtaagta tattaagtat ggtgaaccta acaagccagt
    11941 tacaacacct actggatatc tagctggtaa aatattttga gagaatatgt ctgataacaa
    12001 aactagtaaa attccaacca atccagctaa tattgggctt cttttcttgc caatatttaa
    12061 ggctatggga ccagctaaaa aagatataca agctattggt cctgtaattg aagtagaaaa
    12121 agcagttaaa gatacagcgc aaaaaattaa aacaagcctt gaaagctcgg gatttgctcc
    12181 aagtccgatt gctatttctt caccaagttc aataatttct agtcttttat taaaaaataa
    12241 aactaatata gtagcaataa tacttactat tagaacaaga ggtatgtcat ctaactttgt
    12301 aaaagataaa gagccactga gccatctcat aacttcttgt aattcatatc ttgctacttt
    12361 caacaataaa aatgaggtgc ctgctcttgt gacagcttga aaaccaatgc ctaatattat
    12421 cagtcttgct gctgaaaaac catctttttt agctagtaaa aataatatta aagatgatgt
    12481 tagtccacaa gttattgaaa taattccagt agttaaacta tttgttttta ataccaatat
    12541 gcaaaagacc gctgcaatag atgaagaact tgtgacaccg attatatcag gacttgcaag
    12601 aggatttctt aacatagttt gaaagataaa tcctgccaat ccaaaagacc agccagctat
    12661 aattcctgct aataattttg gtaatctaat ttccataatc gaaaaactag ctccaggaac
    12721 agtttcacta tttaagactt taatcaaagt tgaaaaagaa taactttcat ctccgataag
    12781 taaaatgaaa aatgatagac tgattattat taataaaaat agtgaggaaa atagtgttat
    12841 tctatttttt cttttttgaa tacctataat taaattttgc attagttatt aacccctcta
    12901 tttttcatag ttacataaat aagtactgga cccccgatta ttgcagtaat tatccctact
    12961 tcaatttcac ctggtttacc taacatacgg ccgattatat cacatataag caagagctct
    13021 gcacctataa aagatgaaga aatggtcatt gtgcgtatat ctttgcttat aaataagcca
    13081 caaaagtgag gaactataag acctacgaag ccaataggtc caccaattgc agtaatactt
    13141 gaacataaaa gcacacttgc aattattgca agtgatctta tcctattaac attaactcca
    13201 agaccaacag ccatttcatc acccatagct aaagcgttta aatctgatga aataaatata
    13261 gctatcaaat gacctaaaat tataaaaggt agtagtgtag atatagaaga taatgtagct
    13321 gctccaaggc tacctatttg ccaaaatcta aatttgtcta agacgttatt attcggtaaa
    13381 attaaaaaac ttacaaaact gcttaaagcc atactaacac aagttcctga taaggcaagt
    13441 tttatagggg taaggcctgc ttttccgctt acagcaatcg cgtatacaaa aattgcactt
    13501 actaagccac caatgattgc aaaacttata tggcttatgc ttgatgaaat tcctaaaaaa
    13561 gaaagaccaa ttactacact aagacttgct cctgtgttta taccgagtat acctggatca
    13621 gctattgggt ttctagtaac tgattgcatc aatacaccgc ttatggcaag actagaacct
    13681 gctaaaattg caaaaatagt tctaggtatt cttttatata taattgattt aataaaatca
    13741 tcatttgtat tacccattcc aaaagctgct aaaaaatctc tgatattaat ttcttttgtt
    13801 ccaagcttta atgacaaaaa tattgtaata agaagaccta ggcagattac aaaaattatg
    13861 cctaggttta tttgtttttt atttcgcatt tttgcatgca tttcctaaaa gatttaggta
    13921 ttcttcaata gtatagttta ttgaaagtgg tgttggagtg catgaggctg ctaacggtgt
    13981 attatctgga attacagcaa cggcaccatt tttaattgca tttattttac ctaaaagagg
    14041 atctttttgt aaagcttcaa gagttttatc atcaccataa gttatgatta catcagcatc
    14101 atttatctta tttgcttctt ctgcagaaat ttcctttgca aaactatctt cactctcaaa
    14161 ttcttttaat gattcaggga aaactagacc taaatctgtt aaataatttg ctcttggatc
    14221 tttgctagta taaatccaga attttgatgt atctgcagca ttaatcatag taaataatac
    14281 tttttttcct ttgatttttc ctttgatttc tggatgtttt tctaattctt tggatatacg
    14341 agcttcagta tttttgatta actcatcacc ttctttttcc atacctaagg cttttgaatc
    14401 aattttaatc atatctctcc ataaagtttg ccaaggttta gatttgtatg ctgctacagg
    14461 agcaattttt gatagagtgt cataatcttc tttagttata ccagaataac ctgctaagat
    14521 aacatctggt ttagaatttg atattgcttc aaagttaagt ccatccaaat cgtcaaatag
    14581 gttagcttta ccatttagtt ctttgatttt ttcttctgtc catggtaaaa ctcctttatc
    14641 agcacttaca ccgtaatttg cttttgaaaa tccaacagga actattccta aagctaatgc
    14701 tacatcatga tttccccaag caatagttgc aactctttca ggttttttat ctaatatagt
    14761 ttgaccgaaa gcatgatcta aaactatttt atcaggcgca tgctctttag aagtattttc
    14821 ttcattttta acagaattag aagaacaagc gctaaaaact atacacatag ctaaaatagc
    14881 tattagaaaa aatttgtttt tcataaaaac tccttaaaca tatttcaagt ctattgtatc
    14941 gataataatt atcattgtca atagatacag ttacaaattt aataatataa ttttttcaaa
    15001 aaaggatcta gtttttattt ttagttaaat tatgtctata tttttcatta actcatcaat
    15061 aaaaatttgt ttgctaatat ctctttcttc tgattttgtt tcaaggatta ttgctacatc
    15121 attcatattt ttaggtaaat accaaccatc tggcttatct gaatatccct tgaagcctaa
    15181 ttgattaaaa gtagttattt gaccagtacc ttgattgatg ttttcttcaa cttcattaaa
    15241 gcctatactt ctcttgcata atccctaact tgatcttctg tccttaaagt cattttctat
    15301 tcctcgtcac taaaattatc ttcaaaacta ataatatcat taggagtgca agataaagcc
    15361 ttacatattc tttctaaatt cttaaatgta attggtttat cctttcccat ttgtgccata
    15421 acatttgttg taagtcctgc catagctatt acatctgttt tctttagtcc tttttttgct
    15481 aactgtatcc ataatggttt atagttaagt gccataatat ccctcttttt ttcttcatta
    15541 gatttattta attatagcat aaatattgat tttattcaat cttacattga tttagtgatt
    15601 tgttttagag aatttgttgt gttattccgt ccttattttg ccataaattg ttttaagtgg
    15661 gacctcttat ccttaccatt tttacctcct aattttgagt ataaaaaaga cgatagagtt
    15721 tttaatttct atcgtctgag atttacatat taaattttca tcacaaaata agactcttta
    15781 aagaatcttt aaattcattg gtatgctgct tacaatatcc attattaaaa tggatattgt
    15841 aagcagcata ccaactattt attttttgag ttttaaactt tggtagaagt cttgaactcc
    15901 ttatatttac ataactattt gcctctataa ctgttatgac acgaaaccaa caagcaagtt
    15961 caagcacctc catatcttta ttcaaatgag gactaagata ttcacaaact ttatcataaa
    16021 cctctttatc ttttttcata aaaggggcat acaacttagc aaatttatcc taaaattttt
    16081 tgttgccttt atcaatcatt tcaacgctcc tttaaatata aaaatgatcc tatcaatctt
    16141 tatattgagc ctattttcta attgatacct tgcaagaaag gaataatagc tgttcctata
    16201 ccaagtagga atgtaataaa tgcagaaagt catatactgt cattcttttc tattaaatca
    16261 ttttgaagtg tctcaaagca tccatgatgg cttcttcttt ttcaggtgta cactgtggaa
    16321 taatttgttt atccttttta gacttgttgt aatgttctcg taattctatt ccacatttct
    16381 tttttatctg tgcaatatat aatgtcgaaa cttttaattc aaatttattc caaacatatt
    16441 ctttgatttg agcatatgtt gctttgctct ccgcacttgt caaatccatc tcatccagct
    16501 caatttcaac acttatgtgc ttatcgacat caagtttgga caaaagtgct accgtctcga
    16561 cgtgatgcgt ttgaggaaat agatccaccg gctggacttt cttcaattca tatcccaatt
    16621 cttggtagag tttgatatca cgcgccatgg ttgcgacatt gcaggagata taggcgatgc
    16681 gatcggctcc tgtttgggcg cttgctttga taaagctttc tgtcaagccc ttgcgtggag
    16741 gatcaaccaa gataacggtt ggttgaatcc catctttaag ccaattcttc atagcatttt
    16801 cagctgtgtc acagacatag tgggcgtttg aaatattgtt cagctgagca ttttttttac
    16861 tattctcaac cgcttctgga atcagttcaa caccgtagac ttctttgaca tgcttggcga
    16921 ctgataaacc aatggttcca ataccagaat aagcatcaat aaccacgtca tcttttttta
    16981 actctgcaaa gtcaatggct gtttgataga gtttctccgc catttcagta ttgacttggt
    17041 aaaaggctgg gccagcgatt tggaagtcat ttcccaacat ctggtccgta atatagtctt
    17101 gaccataaag agtgcgccac tccttaccaa aaatcgcatt ggtattctgg tcgttgatat
    17161 tttgcatgac agacacaatc tctgggaact gcttgataac ttgttcaatc aattggtcaa
    17221 cacgaaaaac ttttggacga gttgtcacca aaacgaccat gatttgtcct gaatagtgac
    17281 cacgacgcac cacaagattc cgaatcaatc cagactgttc cttttcgtca taaggtttta
    17341 aatcaaaacg acggagcagg cctcgaagag ctactacgac ttggtcaatg acaggatcct
    17401 ggataaagaa atcttcaagg ggcatgaggt cgtgcgaatt cttacggaaa aatcctgttt
    17461 ccaagacacc attcactcga cgaacgggca cctgcgcctt attgcgatac ttgactggat
    17521 gttccatacc aagcgtttca gcaacttcta catctgcaat tccagcaatc ttgtagagac
    17581 tgtccttgac ttgcttggtt ttaaacttga gctgttctgg ataagaaagg tgtcctaaat
    17641 ccgcgattcc tgaacgcagg taagccaaat ctagatcttg attacggtgt ggtgactgga
    17701 caaggtattt ttcaactttt ccaaagccaa tctttttatt gaccttgagg acacgcatga
    17761 gaattttttc actcggtaaa gcattctcta caaaaaagac caaaccatct accttggcaa
    17821 ctcctgcccc ttcatgggtc aagtcaacaa tttcaacttc tacaatatca tttttcttta
    17881 acattctttt ctctttctat tggccgacaa aaaagacggt aacgttacgg ttaccatcca
    17941 ttataccatg aaatttctta agaaccaaaa ctcttgaaga agttgacaag ggcttgccag
    18001 agggagctta agaagttact accgtcctct agcgccttat ccgcatcaaa gttaaggttg
    18061 atatttttaa aactgtcgcc agcttgtgat acgatgcttt gtttaaggtc atttagggtt
    18121 ttagtgaaat ctgcattgct gaggatatca ctctttgaga gattcaaggc aaaattgatg
    18181 atgatattga tctggtttcc tgttatgacc tgatcaagtt tgtaattttt taaggtatct
    18241 tcaacaatct tgcggatatc ttcttctgtc agatttccct tgctttcttt agctttggcg
    18301 agtcctgact tgatatcagc tagggcaacg tttaatttat tagcatcata gcctgatttg
    18361 tccttgtttt cagcattgat atctgacaaa gcttttagct cttcttgagc caaatcttta
    18421 ttagcttgtg gcaccttggc tccattagcc tctagcgaat agtaaatccc tgctaaagca
    18481 ctttctcctg taactggaat aggggctgct acagtgattt tggcatgttc catacccagc
    18541 gttactgctg cgtttcggta catatcctga gtcaccttag tgatattttc tggtgtttca
    18601 atcttgacct caagtggcga tttgtcacct agcttttgaa tcttggctga tgaatacaac
    18661 tgtaagctag agtcattggc cacattcatg attttagaat aaacatcagg tgtcatggtc
    18721 ttgagttctt tggtatctgt tgaggcattg tagcccagtt ttttaagagt ttgatttttt
    18781 tggtcttcag atagggagga acctaggaca tattcaggtt ggacataggt ttcatcgata
    18841 actttttgaa catctgttgc tgcatggacg ctattcatag ctgttactgc ccacaagacc
    18901 gcagcactag tcagaaagag tttctttctc atagggaatt tcctccttta cttctttata
    18961 gtaatatatc tatcttaaag aaaacttata acaaaaacac ctggtctagc cagatgttga
    19021 aaagagagtg aaacatttga tgatgtaaag gttaagtcgt acctgtctag aataataata
    19081 atttcctcca tttacataga gttcagcacc gtgaaaaatg gaaatggggt gaatataact
    19141 ataagtcttt ccagtcgtat taccaagcaa gggggcaaca gtctcacgag agtactgttt
    19201 ggctagagcc aaggtatttt ccttgccatt ttgggcgata aaatcgatat aggcaggtcc
    19261 aaaattatag gcttgaacag ctgtccagat atctacaccc ttcttctgcg ccagatagag
    19321 attgcctgtc agagtttgaa tgccttgccg aatgctagag gcattatcat tgatggtgtt
    19381 ggtggaacca cttgcagact cactagactg cataacatcg ccttcttttc cttttgtttc
    19441 agtataaatc atagcaagca caagctcttc gtttgctggg gtgtcttttt cactcaagat
    19501 ttctcgcacc atgggttgat aggtcatgac ttgtttgaca tcttgatgaa cgcggtaagc
    19561 tttatagcca gcaaaaagga agactgctag tacaagcact cttcgaattc gtttaaacat
    19621 tatttacttt ggatatcctc gatatttttg attaagatag agtaggttcc attttcgttt
    19681 tggataaact caacagactc ggcgtcttga tagacgttat tgggaacgat gagctcaatt
    19741 ccatttgata aggagagttt ttggttttca aatttcttta attggcgact tgcatcaatt
    19801 tcatcaaatt gaacaggttc tggtacggct tctttgactt ggtcaataaa gctcaaacga
    19861 gccgtcagat tgttgtcaaa aaggtcatta gccaatttct caggtgacaa ttcattgctt
    19921 tcttctaggt tgttgaaaat cgctgatttg accttggatt gaaattgaaa atcatctgtg
    19981 ttaaaagatt cagcaattct ctgggctgtt ttttccagtt ccttgataga ttttttagga
    20041 gaaatcttag gagcgacagc aagaagatta tctgaaaaat agttcaaaaa agtcccgttg
    20101 tacttgattc gtttttcaat caggtgatac ttgcgactct gaagattgac caccaaggcc
    20161 tcgtcagcac ccgttccaaa tccaggcagg ttattctgag tcagcttgat tggattatca
    20221 acttctcctc cgaggtgggt caaggtctcc cgcagggcaa ttcgcaagaa agcgaaatgt
    20281 tctacacctt ctttagaaaa ttgaacaaaa atcaagtcat tggtcttgag attttcagaa
    20341 atgctaaact cctctttcca gagattagcc agcgttactg atgtctccaa caaatcgtct
    20401 gtaatatgat tgaagaaggg attttcttct tcgaaaatcc cagtcttggc ttcatctgaa
    20461 tacacatgtt caattttttt acgtaggtat tcttcgattt ttggagtaat attgagaaac
    20521 ttatctgcta agaacagctc ggtatcatcc ggactgaact ggtgaataat ggctttctta
    20581 atataaatgt ccataaaagt tttattcctc gtataatggg aaggcatctg tcaattcttt
    20641 gactgcactt ctcacttctt ctaatacagc ctcattttct gaattcttaa gggttttaat
    20701 gatgagttca gccactttgc gactttcttc ttcaccaaat ccacgtgcag taatagctgc
    20761 tgctccgata cgaatcccac ttgtcttgaa tggtgacaag gtttcgtaag ggattgaatt
    20821 tttatttagg gtaatattga cttcatccag caagttttga gcaacttttc cgttttctac
    20881 aaccttagtc acatcaacaa ggaagagatg gttttcagtt ccacctgaaa taatacggaa
    20941 atcagggtct tgcaagaaga catctgccat agccttgctg ttcttaatta cattggcagc
    21001 atattccttg aaagctggat ccaaaacttc tttgaaggaa actgccttag cagccacaac
    21061 atgctccaaa ggaccaccct gaataccagg gaaaatagct gaattgattt tcttagctaa
    21121 atcctcatca ttggtcaaaa tcaaaccacc acgaggacca cgaagggttt tgtgggtcgt
    21181 tgttgtagtg atatgagcgt atggcactgg gcttgggtga agaccagctg caaccaagcc
    21241 agcgatgtgg gccatatcaa ccataagctt agccccaaca gcatctgcaa tttcacggaa
    21301 ttttgaaaag tcaataattt gagaataggc tgaagcacca gctacaatca gttttggttt
    21361 tacttcttgg gcttgtttca agatagcatc aaagtccaaa agttccgttt caggatccac
    21421 actataggaa agaaagttgt aggtttgacc agagaagcta actggagctc cgtgggtcaa
    21481 gtgtccacct gctgccaaat ccattcccat aaccgtatca cctggctcaa tcaaggacat
    21541 gtaagccgca cagttagctt ggcttcctga atgtggttgg acattggcaa atttagcacc
    21601 gaaaatttct tttgcgcgtt caatagcaag agtctctaca acgtctacta catcagttcc
    21661 accataataa cggcgtcctg ggtaaccctc ggcatattta tttgtcaaga tagacccttg
    21721 agctgccata acagccttgg aaactacgtt ttccgaagca attaactcga tattattttg
    21781 ttggcgttct tcttctttgg caatagcatt ccagagatca gcatcatatg ctttaaaatc
    21841 atctttgtca aaaatcatag gtcttctcct ttattgtgtg actagtccat tagtttgatt
    21901 ttacaataag aaaatcaaac taaaagatgc gaataaaccg tttctgcatt ttatcacaag
    21961 tatagccaac tttttcataa aatgcatgag cacccagacg atgattggca gaatttaagc
    22021 ggataaaccc ataaccacat cttttggctt cttgttccaa cccttgtagt aaacttttac
    22081 cgataccttg accttgcgct tgaggtgaaa ctgctaaagc taagatatta aatcctgctt
    22141 tggaatagag tgattcgtaa acttcagcgt ggacatatcc aagtaagaca tgattagctg
    22201 catcctcata gccaagtagg aaatgatggg aatcctgaga cagtctagct agttggctag
    22261 ccgtttcctc tggactaaaa gtataaccca aagcctcttg gttgatgtca catatcgctt
    22321 tcacatctgt ttcttgcaaa tctcttagca tttcaagcct cctcaaaaga aatctctggc
    22381 aaccgagcaa gaatatcttc tcgtttaatt gcgccttggc gtaagatttt caccttgtct
    22441 ccagacaaat ccacaatagt tgaatcctgt ccagttagaa aagcatcgtc ttccagaccc
    22501 agaacctctt ggtcaaaatc cttcagaatt tgttcaaagg ttacaccact tgcctgacct
    22561 gagatattgg cagacggccc aatcaaggga cctgtctctc gaattaaatc cagtgtgata
    22621 gggtgactgg gcatccgaaa tccaatagtt gcaaggtcag aatttaccca atagggaact
    22681 cggtcattgg cttcgagaat aatggtcaag ggacctggca aaaaggtctc tacaagtttt
    22741 tgtagataag ctggctgatt cttagaaaag tgcaagatat cctctaaaga ggcaacattg
    22801 agattgagcg ccttgtctct aggacgacgt ttgagctggt aaacatggtc aactgctttt
    22861 tcgtctaagg ccttggcaaa aagaccataa accgtctctg taggcagaat gacagctcca
    22921 ccattttcca actcttgtct aatcctgtcc atcatcaacc acgaccatcc tatcttgacc
    22981 aaattggtcc ttgagtgttc gaactctttt ttcaggaaga tgtttcctaa aaagttcggg
    23041 aacactttga ccttgcttgt atccaatttc aaggtaaatc ttaccaccat ccttgagata
    23101 gtcttttgca tcttccgcaa ttctacagta aatagctagg ccatcctcgt ctgcaaagag
    23161 agctagatga ggctccgaat gcaaaacatt caagcctacc tctgactcat cttcacgaga
    23221 gatatagggt ggattggata caattatatc atatttttca gaaatttctg caaaacaatc
    23281 agatttttta aaaaatatat taagattttg atcgctagca ttctctgatg caagctctaa
    23341 ggcctcttga gaaacatctg ctgctgtcac tgaccaatct ggtctatttt ttgctagagc
    23401 gagagcaata gctccactac ctgttccaat atccagaact gagagattcg tctcaagatt
    23461 ttcagttaga ataagctcca ctaactcctc tgtttctgga cgaggaatca aaacccgttc
    23521 atccaccttt aaatgcattc cataaaaatc tgcctgtcca atgatgtact gagctggctt
    23581 gtgagctgct agttgctggt aaatatcttc tacaaattgt ttttcttcct ctgttgtcac
    23641 ctcctgctgg agggcaaaaa taaagtctgt aaaagataga tttttcagac tacgatagac
    23701 aaaagagagg ctttccgctt cctctccttg tcttatcaac tcttcttcaa aatttgaaaa
    23761 taattgagct aatttcatta tttgtttaat tcttctagtt tttgtgtttg gtcataaagc
    23821 accaaggcat ccacaacttc gtccaattta ccagacaaaa tcgtatctag tttttggagg
    23881 gtcaagccga tacggtggtc tgtgacacgg ttttgtggga agttataagt tcggatccgt
    23941 tctgaacggt caccagtacc gattgtcgac ttacgctcag cgtcttgttc atcctgagca
    24001 atctgagcaa agtggtcagc gacgcgtgca cggataatct tcatagcctt ctcgcggttc
    24061 ttctgctggg tacgttcttc ctgcatctca accttgatat tggttggcaa gtgaacgata
    24121 cgaacggcag tcgcaacctt attgacgttc tgtccaccag caccagaggc gtgatagatg
    24181 tcgacacgaa ggtcttttgg atcaatgtcg tattcaacct cttcaacttc tggcataaca
    24241 agaactgtcg ctgtcgaagt atgaacacgg ccttggcttt ctgtcacagg aacacgttgc
    24301 acacggtggg cacctgattc atacttaagc ttagagtata cagactgacc tgaaaccata
    24361 gcaaccactt ctttaaaacc accgacacca ttcatagagg cttccatgac ttcaaagcgc
    24421 caaccttggg cttccgcata cttttggtac atagttagca aatctccagc gaaaagtgcc
    24481 gcttcgtctc caccagctgc tccacggatt tcaaggatga tattcttgtc atcgtttgga
    24541 tcctttggaa ggagcaaaat tttcagtttt tcttcatatt cttctttttc agccttggca
    24601 tctttgagtt cttgcttggc catttcttcc aagtccgcat ctccgcctga ttccttaatc
    24661 atctcttcgg catcgacgat attttgaagg acttgtttat actcacggta ggctattacg
    24721 gtgtcacgat tggaagcttc ttcttttgaa agctccataa aacgcttggt gtctgaaacg
    24781 acatcagggt cactcagcaa ttctcctagt tcttcataac ggtcttctac agcttgtagt
    24841 tgatcataga tgttcatttt ttctccttat ttctcaattg ttaaatcata gattgctact
    24901 acttcattct cggctatttc cccagtttct ttaaatccat aactgaggta acaaaatctt
    24961 gcctgttcat tttctggttc ataagacaac caaagtttat tgcttaaacc tgctggcgct
    25021 gttcgaacat agtctagtac tttatccata attggtttaa aatatccttg attttgaaaa
    25081 ttcctatcaa tcataaaacg aaatagtaaa taatttccac tactaattcc gatcttttta
    25141 tcataagcta tcatcacaaa acctataatt gcatcattat cataaactgc caatgtagct
    25201 acaaaatctc catttttagt gtagacgtat gcttcagcta aactaattgc gttggttgca
    25261 atgaattgtt tttgatattc cttgacatcc aaatttaaaa catcaaaata attttccatt
    25321 gtaacatctc ttagttcaat tgtcatagtt ttgctccttg ttagaggtta tcattggcgt
    25381 aaaataatgt ttacggcaaa ctgagatata ggtttcgtta ccaccaatct ggatctgttc
    25441 tccatcgtaa acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca
    25501 atactgacag atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga
    25561 accttcgaac aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc
    25621 taactcgtcc acaacacgag ctaggtcgta aacatggtgg cgtttaagaa actgggcttc
    25681 atcgaccaaa acacagtaag gtttttctgg taggtctcgg atatagccaa agatatccgt
    25741 tgtttcctca atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac
    25801 accgtcacgc gtatccagag ccgaggtcat aatgacaaca ccttttcctt gctcctcgta
    25861 gttataggcc actttgagaa tctcaatcgt tttaccagag ttcatggtcc cataacgata
    25921 gtacaactgt gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt
    25981 atatcataat tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac
    26041 tagtggagga agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg
    26101 agcaaaagaa agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc
    26161 ctcaatctgc tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag
    26221 gggaaatgcg tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca
    26281 agtagcattc attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa
    26341 tttccaagaa aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc
    26401 atcgctgcta tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga
    26461 acagacagtt ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc
    26521 agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag
    26581 gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt
    26641 aacacccacg gtgggattgc ggtgaccaat gaaattctcc agctagctat tcgtgaaggg
    26701 gctcggttgg cagaacctgg tgaatttacc aaacgtgctt ttttaaacgg tcgcgtagac
    26761 ttgacacagg cagaggctgt gatggatatc atccgtgcca agactgacaa ggccatgaac
    26821 attgcggtca aacaattaga cggctccctt tctgacctca ttaacaatac ccgtcaagaa
    26881 atcctcaata cacttgccca agttgaggtc aatatcgact atcctgaata tgatgatgtt
    26941 gaggaagcta ctactgccgt tgtccgtgag aagactatgg agtttgagca attgctaacc
    27001 aatcttctta gaacagcccg tcgcggcaaa atccttcgtg aaggaatttc aacagctatc
    27061 atcggacgtc ccaacgttgg gaaatccagc cttctcaaca acctcttgcg tgaggacaag
    27121 gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc
    27181 aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga tgacatagtg
    27241 gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt ggttctacta
    27301 gtgctaaatg ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa
    27361 gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg
    27421 aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt
    27481 gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca agatgctact
    27541 tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc
    27601 gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt
    27661 acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa
    27721 ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg
    27781 gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg
    27841 cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg
    27901 gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa
    27961 ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa
    28021 ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat
    28081 ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga
    28141 aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt
    28201 aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca
    28261 agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa
    28321 taattggtag gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag
    28381 aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta
    28441 cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag
    28501 gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg
    28561 tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca
    28621 ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc tcatggaagg
    28681 gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac acgaaaacac
    28741 ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca
    28801 aatttcaatt cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga
    28861 actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct
    28921 ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca
    28981 ttgatagctt gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag
    29041 gctgcgatag ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca
    29101 gactcagagt gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta
    29161 tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca
    29221 ttatcagtga aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg
    29281 tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg gtttcacacc atcattcaaa
    29341 acctcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct
    29401 tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc
    29461 accatcattt ggattgttga acaattaggg caggcaatga ttccgttgtg agcatcaagt
    29521 gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat
    29581 gtattatcta ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta
    29641 gaactacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct
    29701 tcaattgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca
    29761 aggtaacgaa ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca
    29821 ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg
    29881 aattttctaa aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc
    29941 tttttcatca ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat
    30001 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    30061 ttatgctcaa tagtagtccg aagactacct atcgactcat cgcatattct atattactag
    30121 agatacttga ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta
    30181 ttcaagagtt tccctataca tatcatgcta attgccggga ttgaaccggc gacctcatcc
    30241 ttaccatgga tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat
    30301 tcagaaaaac ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact
    30361 acctagctta tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata
    30421 atcgccccaa taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag
    30481 aatggtaatt ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag
    30541 aggattgaaa agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta
    30601 tattttgcaa aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca
    30661 aagacatcta gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg
    30721 atgatgtact taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga
    30781 taagcaccat agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca
    30841 gcgacgattg caatatctgc aacatcacga atagttaatt ttttcatctt ttctcctttg
    30901 gcggttgccc gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt
    30961 caaccctact agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc
    31021 tattcaaaaa ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac
    31081 tctagtttcg attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc
    31141 tactgcccta gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt
    31201 atttaagcaa aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct
    31261 ttctactttt ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat
    31321 tatagggcaa ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc
    31381 acaaatattc attattatca tcaattatat cttgagcaag gcctatattt ttagaaaata
    31441 atgctccatt tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac
    31501 gaaacattga aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa
    31561 tgttattgac cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc
    31621 acttgtaaac gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt
    31681 tgaacgtatc gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat
    31741 tatcaatttt atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc
    31801 acagaaactg actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga
    31861 agtccttcaa gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg
    31921 caaagctaaa tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt
    31981 tttgatcaga taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac
    32041 aaattctggc atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg
    32101 aactaactca tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt
    32161 gactctaact gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtga
    32221 acgatggtag tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa
    32281 caagacctca atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg
    32341 ttctgtctgt tctctgagat actccaaaac aaaggatcac caaagtccaa ggcaaaaatg
    32401 ggcacactat gggctgaaaa gatgacttta aaactgtctt gctttacttc ttcttttaaa
    32461 atcttagcaa tttcatctgc ccaatagttt aagagcactt cttcctgata ccagtcctta
    32521 atgaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag
    32581 aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt
    32641 tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat
    32701 tcattcccca gcctagcttc taccaaggta acctcttgac gggtaatttt ttgcagaggc
    32761 gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc
    32821 accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt
    32881 gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat
    32941 caagtttatt ttatcattaa ttcatcgata agtaaacgct aacataggga cattctcaat
    33001 cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg
    33061 agttttttta tgacttatcc aaatctcttg gaccgcttct taacctacgt taaggtcaac
    33121 acgcgctctg atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca
    33181 acaaatgtcc taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg
    33241 aatggttttg ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt
    33301 tttatatcgc acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt
    33361 gaaaactacg atggtggtgt gattgaacta gggaattctg gtttcaaact cgatccagct
    33421 gacttcaaga gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaacc
    33481 ttgctaggtg ctgatgacaa gtcaggaatt gctgaaatta tgacagccat tgaatatcta
    33541 actgctcatc ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa
    33601 atcggtgttg gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact
    33661 gttgatggtg gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa
    33721 ttgcatttcc aaggccgtaa tgtccaccct ggtactgcca aagggcagat ggtcaatgcc
    33781 cttcagctag caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact
    33841 gaaggttacc aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggcgcgt
    33901 gcaagctaca tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg
    33961 caatctatcg ctgataagat gaatgcagaa cttgggagct accgtgtcac tctcaacttg
    34021 acagaccagt actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt
    34081 gctaaagccg ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccggggtgga
    34141 acagacggct ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc
    34201 gaaaatatgc acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat
    34261 accatcattg gcatcgtagc ttataaaggc taaaaagacg aggtagctca gctacttcgc
    34321 ctttcttttt attctactgg tttttcttga tttccagtag ttgtagaaga ttctgttgtt
    34381 tcattttctg aagttgattc agcaggttta gaatctcttg tattgcttgg tttgttttcg
    34441 tcgctagcaa tttcaatgtt agattctgca gttgcgtttg gttggttctc agcactggtg
    34501 ttatcactat ttgcttcagc atttcttgct ggacttgttt cttcacttgc gctagctttt
    34561 gactggattt gatgattcaa aactagaata gcttttgtcg attcaagtaa agctgttttg
    34621 tctttactct tagcagaaag ttgatctaat aatgcatcca ccttatcaaa gtccgcatca
    34681 gatccattat tactttctaa ataagagtga agcgacatga gaatatcgta gagtttttga
    34741 tagagtacaa gtgtctgaga atcttgctca gcattttcct tttcttgttg aagggcgcta
    34801 gcgatacgag tcaagacatc ttttacctga ctgtttactt catccaagtc tgcatcagcc
    34861 ttgtttgtgg cagcttttag attttctact tcttctgcca aggattgtct gattccttct
    34921 tcatggattt gttccaagag ttgatttacc ttgctcaaaa gactttctac ttcttccttg
    34981 ctatctgtcg cagattattg gttgccatct accatgtact cctaaaacag gagagttata
    35041 atccaagatt acaaggcctt acagaaataa gaaatccaga taagacaatg ttcgtccaag
    35101 acgctattcg cttcgcacag cagcacggat tcaatatgct ttaattttaa agtttaggtg
    35161 tcaagacctc tttttagtgt gcccaaaatt tagagaagta atcaatcaac taacttttat
    35221 ttttttcaaa ctttcagtaa actgacctaa agctaactca atctgtcttt gtagatgctt
    35281 ctgctatcag ctagaagttg atctactttt gccaagactg ccttctcatc aaaagttcca
    35341 ggttgatagt tggattgcag ggatggaatc ttgtttttca aagccgcttc atatccctta
    35401 gtttgaacct tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc ttctgaatct
    35461 tcacttataa ttcgattggc atcaaaacca tgaccatctt cttcctcatg atggacatgt
    35521 agtgacggat tacttaatac agaactagaa gaacttccta cctcttccgt gttagagtgt
    35581 gatgggggat tgttaagaga tgacttagga atatagtgat agtgatcccc atgtcttact
    35641 atataagcat cacctgtatc tctgacaata tcattagggt taaagacata tgtggctgct
    35701 aattcacctg ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact
    35761 atagtagatt gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac
    35821 aatgatttag aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc
    35881 ggtagtataa cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc
    35941 tttaccatgt tcttgttttt ggcgattgat ttcatctttt gttcgtacat tttctgcatg
    36001 agcttgatct ttaaggtaaa cataatactt tccatctacc ttaataatat atcctccctt
    36061 aacctaactg acgatatctt gatctttcgg ctgatagttg ggggctttca ttaatagctc
    36121 ttcactaaag agcgcatcaa aaggaacttt accattatag tagtgataat gatcgccatg
    36181 agaagttaca taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc
    36241 tttttgacta acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt
    36301 tacatatgaa acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata
    36361 aacacacaga cttaaggaaa ggataacaac agatccagct gctatatatt tctttttaaa
    36421 tttcataatt acctcatttc tataattatt tatatgatgt cttcattatt aaatgattaa
    36481 ataaattaat taaccaatta attaactagt aaatattcca cctcttttta agttgtatgt
    36541 caagaaattt tatatattaa taataaaatg aaattctccc aaagtcagag ttttatttct
    36601 aacttttgag agaacttcat ttttgattca gactttttct actgctattc cttacgctat
    36661 gagatcagat aaattctttt ttatcacttc tccacttggc aatcttaatt caatcgttcc
    36721 atccatattg aatataacac tatctaagcc taatccgtaa ctagctgtaa atttttctaa
    36781 tttttcttgt acaggatcta ctgctggagc ttcctctaat gctggatcta acatagggtc
    36841 actccccaca ttcccttctg gattcaacat tccattatcc gttgagtttt ctggttttac
    36901 aggtttttcg tttggtgcct ctggtaaaga atctgctggt ttattttctg ttggttggtt
    36961 ctcaactgtt ccagtagata cttttccagt ttcagatggt ttattttcac catttccttg
    37021 aggtgcttct cctgtaaaat ctgccatatt ctttttaatg acttctcccg atggtaaata
    37081 taattcaatt gttccgtcca tattaaacaa gacattttct agcttcatcc cataactttc
    37141 agcaaatttt gctacttttt cttgtacagg atccactgta ggaacttctt ctaacgttga
    37201 atcactagta ctgttcccag tttcaggaag cttttctttt tctaccttct cactagtctt
    37261 tggttcttct accttttcat caagttttga gttttcttgt gctttattcc ttttaaattg
    37321 tggtagaata cttggtttat cagtttgatt ttctttttcc aagataggta cttccacaat
    37381 ataagtcgat tgattgtcca aataagcatt tgccatgaag gttacaggaa ttttatttcc
    37441 ggccgttctg gttgttcctt ggtttaattt cggaatcggt aatttaattt caccaacttt
    37501 atagttattt tctaaataag catttccatg aaattcatca aacactctga ctaaagcatc
    37561 agttccttta ggcactgcaa attgagggtt cactcttaaa taagtatccc ctgcatggaa
    37621 aggatagaaa atcgtttgac tggccatttt gtaagctaaa gaggttggaa ctgtaaatgt
    37681 accatcataa cttacttctg gataatcttt tgaagcgata gtatacttaa atgtttgtcc
    37741 tggtaaataa ggttgatcta attcaaagtt tgcaatattc cctactcctt ctccaaatac
    37801 tttaccagat actttctcca atacttttcc atctggtgtt attaatttta ctagcatatt
    37861 gatacctaat tttttttcca attcaggcgg aaaactaaaa gaaacgcgtt tttgaccatt
    37921 ggctagagta aagttttgat tattaaacgt actatttttt aacaaattaa caacattcgt
    37981 taattcttct ccagtataaa ctttattccc ttctttttta gcaactcctt cttcgggttt
    38041 aaacagttca tagttactgt gagaatgacc aattccaacc ggtttatgtt catcaatcgg
    38101 atctgcatga tggtgatctc catgcggata aataatcgca tttttttctt tattcacgac
    38161 aatactttca cgtttgacac catattgttt cataatgcca gcaatttttt cttcgatttt
    38221 tttatctaaa tctttcattt ctttggcatt acctggataa tcctgttcat gagatgacaa
    38281 agaatctaat ccattatgac tagttttaac ttcctctaaa tgtttttgcg cagccttaat
    38341 ttgctcttct gtcaagtcct tcttgaagaa ataatgattg tggtctccgt gactcatgac
    38401 aaaacctgat tcatcttcag cgataatacg attagcatca aatccgtatc catcttcttc
    38461 atgtttctca tgtgaagttc ctggattgat tggaagagat ggagaaggtg ttgctagact
    38521 attgtttgga agagtcggtt gcccaatttg atttgatttt ggaatgtaat ggaaatgatc
    38581 accatgtctt acaatataag ctgtagccgt ttcttcaacg atatcttttg gattaaaaat
    38641 ataaccatca gatgctgaag agagtttctt acttgtcgtt aaagaagaag gattgcttga
    38701 aagactgcct agactagaca ctacttcatt aggttttgca tttgtagaaa ctgtagaacc
    38761 agttccactg ataggcacca ttctggcaat cttttcttct aaggcagaaa gcttgctgta
    38821 aggaataaag tggtaatggt cgccatgcgg aatcgcaact ccatttggtg tacgactgat
    38881 aatcttagca gggtcaaaga ccaggccatc tgattcactg taacgttggg cgctaggtga
    38941 atcatagagt tccttcaaaa gactctggag attttcagat ttatttgctg gcttgctagt
    39001 tgatcctttt gctacagatt gcgtgttatt gtcactagct gttgaagaat agcttaactg
    39061 actcggttgc atattttttc cagccagatg tgctttagct gctgctaatt cactagcaga
    39121 taaatcgctt ttgggaatgt agtgatagtg acctccatga ggaacgatat aagcattacc
    39181 cgtatcttcg ataatatcag ctggattaaa gacataacca tcatttgtcg tatatcgtcc
    39241 ctgagacctt gctacagcaa cattagagtt aaccttctca ttatctttga catgttcttg
    39301 tttttgacga ttgatttcat ctttagttcg aacattatca gcatgagctg catctttcag
    39361 gtagacataa tattttccat cgaccttgat gatataacca cccttgactt cattgacaat
    39421 atcagcgtct ttaagttgat agtttggatc cttcatcaag agttcttcac taaagagggc
    39481 atcataagga actttcccat tatagtaatg atagtggtca ccgtgtgacg ttacatagcc
    39541 ctgatctgta attttgatta caatttgctc agcctgaatt ccttctttct ggctaacctg
    39601 gtctggtgtc aagttttcac ttttctgact tgactggctg ccatccacat aagagacacg
    39661 attattgtcc ttattttcct gcgaacgatg ctggtttagt gcataggcac atagactcaa
    39721 ggatacgata acagctgatc cagctgctat atatttttta ctaaatttca taaatccctc
    39781 atttcaataa atgatgaagt ttttttctca acttctttta ctttattaaa tagttttcta
    39841 aaccgattat ttaaccattt aattaaccag taaatagtct actatttaaa attacttttg
    39901 tcaagtttct gttacgtttt tctaaaaaag agaagtaaca cgaaaggtta cttctccata
    39961 aaatatgctc cattcatttt actactgtat aggagccggt tgactttctt ttaacaaagc
    40021 caagagacta tctacttctg ctgaaatagt attattatct ttcgttccga gaagaagact
    40081 actttttaga ccagtcaatg tctccatagc attttgtcta atactagaat ctgttacttt
    40141 ttctagcaag gcctccgcct ctgctatctt agcgttaata acagaatgct ctacttgagg
    40201 aatttcagcc tcatctgtag tatcttcagc ttcttcctct gtctcttccg tatcagtgct
    40261 tggtttataa agattatctg ctgaaggatt taaaccagcg tgattctctt tttcatcaga
    40321 ttcagggtga gttggctcac ttacttcatc atgttcctta tcttcctcag gtttttctgt
    40381 ctgaggttt
//
LOCUS       DAVBOH010000016        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOH010000016 DAVBOH010000000
VERSION     DAVBOH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.016"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(133..373)
                     /locus_tag="VQ873_000908"
                     /pseudo
     CDS             complement(133..373)
                     /locus_tag="VQ873_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(523..1377)
                     /locus_tag="VQ873_000909"
     CDS             complement(523..1377)
                     /locus_tag="VQ873_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3107191.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            complement(1584..2621)
                     /locus_tag="VQ873_000910"
     CDS             complement(1584..2621)
                     /locus_tag="VQ873_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3107192.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            complement(2737..3903)
                     /locus_tag="VQ873_000911"
     CDS             complement(2737..3903)
                     /locus_tag="VQ873_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3107193.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(4202..4606)
                     /locus_tag="VQ873_000912"
     CDS             complement(4202..4606)
                     /locus_tag="VQ873_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107194.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            complement(4613..5428)
                     /locus_tag="VQ873_000913"
     CDS             complement(4613..5428)
                     /locus_tag="VQ873_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3107195.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(5415..6320)
                     /locus_tag="VQ873_000914"
     CDS             complement(5415..6320)
                     /locus_tag="VQ873_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3107196.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(6348..6824)
                     /locus_tag="VQ873_000915"
     CDS             complement(6348..6824)
                     /locus_tag="VQ873_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3107197.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(6821..8608)
                     /locus_tag="VQ873_000916"
     CDS             complement(6821..8608)
                     /locus_tag="VQ873_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3107198.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDFFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            8956..9672
                     /locus_tag="VQ873_000917"
     CDS             8956..9672
                     /locus_tag="VQ873_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3107199.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            9988..13923
                     /gene="strH"
                     /locus_tag="VQ873_000918"
     CDS             9988..13923
                     /gene="strH"
                     /locus_tag="VQ873_000918"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3107200.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(13978..15276)
                     /gene="purB"
                     /locus_tag="VQ873_000919"
     CDS             complement(13978..15276)
                     /gene="purB"
                     /locus_tag="VQ873_000919"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3107201.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(15339..15566)
                     /locus_tag="VQ873_000920"
     CDS             complement(15339..15566)
                     /locus_tag="VQ873_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3107202.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            complement(15576..16667)
                     /gene="purK"
                     /locus_tag="VQ873_000921"
     CDS             complement(15576..16667)
                     /gene="purK"
                     /locus_tag="VQ873_000921"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3107203.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            complement(16654..17142)
                     /gene="purE"
                     /locus_tag="VQ873_000922"
     CDS             complement(16654..17142)
                     /gene="purE"
                     /locus_tag="VQ873_000922"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3107204.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            complement(17545..18807)
                     /gene="purD"
                     /locus_tag="VQ873_000923"
     CDS             complement(17545..18807)
                     /gene="purD"
                     /locus_tag="VQ873_000923"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3107205.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(18929..20476)
                     /gene="purH"
                     /locus_tag="VQ873_000924"
     CDS             complement(18929..20476)
                     /gene="purH"
                     /locus_tag="VQ873_000924"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3107206.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            complement(20501..21010)
                     /locus_tag="VQ873_000925"
     CDS             complement(20501..21010)
                     /locus_tag="VQ873_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3107207.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(21094..21639)
                     /gene="purN"
                     /locus_tag="VQ873_000926"
     CDS             complement(21094..21639)
                     /gene="purN"
                     /locus_tag="VQ873_000926"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3107208.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            complement(21636..22658)
                     /locus_tag="VQ873_000927"
     CDS             complement(21636..22658)
                     /locus_tag="VQ873_000927"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3107209.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(22695..24137)
                     /locus_tag="VQ873_000928"
     CDS             complement(22695..24137)
                     /locus_tag="VQ873_000928"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3107210.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(24230..27955)
                     /locus_tag="VQ873_000929"
     CDS             complement(24230..27955)
                     /locus_tag="VQ873_000929"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3107211.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(28157..28864)
                     /locus_tag="VQ873_000930"
     CDS             complement(28157..28864)
                     /locus_tag="VQ873_000930"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3107212.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            complement(29034..30383)
                     /locus_tag="VQ873_000931"
     CDS             complement(29034..30383)
                     /locus_tag="VQ873_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3107213.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(30396..32549)
                     /locus_tag="VQ873_000932"
     CDS             complement(30396..32549)
                     /locus_tag="VQ873_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3107214.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(33264..33494)
                     /gene="blpU"
                     /locus_tag="VQ873_000933"
     CDS             complement(33264..33494)
                     /gene="blpU"
                     /locus_tag="VQ873_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3107215.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(33697..33987)
                     /locus_tag="VQ873_000934"
                     /pseudo
     CDS             complement(33697..33987)
                     /locus_tag="VQ873_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(34033..34266)
                     /locus_tag="VQ873_000935"
     CDS             complement(34033..34266)
                     /locus_tag="VQ873_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3107216.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(34272..35264)
                     /gene="plsX"
                     /locus_tag="VQ873_000936"
     CDS             complement(34272..35264)
                     /gene="plsX"
                     /locus_tag="VQ873_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3107217.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(35261..36031)
                     /gene="recO"
                     /locus_tag="VQ873_000937"
     CDS             complement(35261..36031)
                     /gene="recO"
                     /locus_tag="VQ873_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3107218.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(36028..37197)
                     /locus_tag="VQ873_000938"
     CDS             complement(36028..37197)
                     /locus_tag="VQ873_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3107219.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            37346..38356
                     /locus_tag="VQ873_000939"
     CDS             37346..38356
                     /locus_tag="VQ873_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3107220.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
BASE COUNT        11140 a         9115 c         7406 g        10750 t
ORIGIN      
        1 ggggtcagta cattcaacac ctgatactat gcgttttttt aattttaaag attttttaca
       61 acttcttttg actcacatta aactattcta atagttaata gacctttgca catatcgtct
      121 caaaacattc atttatttcc gtttaatcaa gtatcggata gccttttcta ggcgttcctt
      181 ttgagcttca gaatcatcta gtggctgatt gatacattca gtaagatttt cggtaattat
      241 catctcaatc acgcgctcta cactagatct cactgctgtc agttgcgtca cgatctcctt
      301 caatcatctt ttgaatccca cgcaactggc cctctgaacg tttcaaacga gtaatatact
      361 ttgaatttgt catttctttt tccttgctcg atttttcttc attatatctc taatcagctt
      421 ctttgtcaaa attctcaccc atccagctca cgcagttctg ttaccaaaga ccgttcaaaa
      481 agcaaactag caatacttat aacttattaa aaattcctaa ttttaccttg ctaaacgaat
      541 acaggtcacg atgccatctg agtctgtgat ttccaattgg ctcgatgtca tccatttgat
      601 tggtgcgtca acttcttgtg ctcgttgggc aatcgttaac agttcttttt tatgtgcgac
      661 ttcgatgaca tagtaggcta aacctggtaa gccttgctta cgcgaagcca gaccttttcc
      721 tccccattcg ttaactgcta aatgatgatg gtaatctcca gccgcaatcc aactagcgct
      781 aggcacactg aatttatcct ctagccctaa caccttttga taaaactggc tggactttcg
      841 actatccttg actgaaagat gaatatgccc cattctcgta ccttctgcca ggataaaggg
      901 ctctactctt tcccccaact cataaatgtc ctgcgccgca agagcctccg tcactccgat
      961 aatgcgtcca tcttctcgaa tatcccatgt ggaaactggc ttatctcgat agagttcaat
     1021 gccatttccc tccaaatctt ccaagtaaat agcttcactg taaccatggt ctgcaccgcc
     1081 gacaagagga atctgtaaat ctgtcaggtg tttcaagaca tcagccaaag ccttgcgtgt
     1141 gggtaagaga atggccaaat ggtaaagacc ataatgttcc ctcacttctc cgctctcttg
     1201 tgcttgaatc agctgtacca agacttttcc accaaggcct agaatggact ctgtctcagt
     1261 ttgagataag atttctaaac caataacttg ctgataaaag gctgtttgac tggccaaatc
     1321 ctttacattt aaaactgtct ctgccaaata aatgtgactc ttgtattcat aggtcataaa
     1381 tggtcctctt ttctcgttgt aattattatt gttacaacta ttatataatt tccatcaaga
     1441 aagtcaagcc agataactca aaaataacac catttcagga taagataaag taaatcattt
     1501 cataacaaaa cgcatagtat caaacttttc atcacctgac aatatgcgtt attttaattt
     1561 taaagacttt ttgaccagct tttttatttc acaacaagtt cataacgtgt cttactggtg
     1621 aaggtttgac cagccttaag aatgacttgg cctttaaggt cactgtgaat ggcatctggt
     1681 aaagcttgcg cttcaagagc aatcccattg tgctgtagca ttggctgacc tcctatgatg
     1741 acactttcat ccacaaagtt tgctgtgtag accacaaagc aaggagcttc tgtcttgaaa
     1801 agcaggaagc gacctgaatt ttggtcataa aggaatccag cattgtcatg gcctgcagga
     1861 agggcaaatg gatgatccaa acctgatgcc agctggattt gctcatcttc ttctgcaaag
     1921 atatccttca acaaggtacc attgtagacg tgtttgacca catcacggtt ggcttctgga
     1981 gttttggcag gaacaccgtc aggagcgatt gagtaaatgc cctctgtgtt tagttggaag
     2041 acatgacggt caatcgtctg cgtgaaatca ccagacaagt tgaaatagct gtggttggtt
     2101 ggattgacca gcgtatcctg atcggtcgtt accttgtagc tgatttcata ggcaccagtt
     2161 tcttccaagt gataactgat ccaaatcttg agatttccag ggaaccctcc tgtcccatct
     2221 gtacgctctg tgtagagagt caagccatga tcgcttactt cttcaacttc aaacaagctg
     2281 gaatcccaac cagttgaacc actgtgatta cagttgctag cattattaac ctcaaggtca
     2341 taggtcttac cattgagctc aaaggtcgca cctgcaatac gacccgctac aggacctaca
     2401 cttgctccat gcttgggact attgcctaca taactatcaa agtcatcaaa tcccaagata
     2461 acattggcaa aatttccagc cttgtcaggt gcgacatagc gcaagatggt cgcgccataa
     2521 gtcataacct caagttggta gccaccgtct gtctcaaatc gataggccaa gacatcctcg
     2581 ccctcaacat ttccaaatac acgctctgtg tatgctttca ttctgttctc cttttactat
     2641 ttctctcaag caaacaaacc atagaaagcg tactgacaat ctatggttta tctgataatt
     2701 tacaaatcct cttgtcaaga attcataaac actgtcttac ttttgatatt cgtgaattat
     2761 gacaccttgt actacacggt ttactgtacc tgtaggagac ggtgtatctg gtttattttc
     2821 taccttgagt gaagtcaata gggcaaagag ttgggcataa acgatgtaag ggaagacacg
     2881 gtaaatatca ttcaagacac cgccacaacc aagggccact tctttgacat tttcaagacc
     2941 aaaagcttga tcactcaaaa gcacaacacg acgagcaatc tggtcaccag caacttcacg
     3001 aaccaagtcc aagtcatact tacgagtgta gtctgtcgtt gtaccaaaga ccaaaacaac
     3061 tgtattgtcg ttgataagag attttggacc gtgacggaag ccaactgggc tttcatacat
     3121 ggtcgcaact tgaccagcag ttaattccaa aatcttgagc tgagcttcat gagcaagtcc
     3181 aaagaaagga ccagcgccta gatagatgac acggttaaag tctaaatcaa caagctcttt
     3241 gacatcttct gccttgtcta aaactttacg ggcaagacta gatacaactt caaaacgttc
     3301 agacttaaca gcaaattctg taggatcaaa gaccaagaga gctgtcaaca tcatagacgt
     3361 aaagctagaa gtcatggcaa atccagcatc attagagaca gctggttgca agagcaagag
     3421 attacggtca tcaccgtgag cttgaagagc caatttacca tctgctgcac aagtaatcgt
     3481 cacttgataa agctcatcca ccaaggattt ggccaaatca acagtcgcca cactttcagg
     3541 cgagttccca ctacgagcaa aagacacaag gacagttgcc acatcttttt tcaaataggt
     3601 tgctggattg gcaacgatat ctgttgtcgc aatagcattg aaattccatt tgcgttcgtc
     3661 atagacttcc ttaaaataag gtagcaaggt atctcccaca taagcagaag tcccagcacc
     3721 tgtcaagata accttaatat agtcatgttt atcagcgatt tcttgtagga aggctgcaat
     3781 ttcttcacgt tttgcttgat aaaattcaaa agcttctctc catacatcag gctgttggta
     3841 gatttcacgc gtagtgattt ctgcacccaa ttcgagcaag tcttcttttg tataatgtag
     3901 cattgagttc ctctttttct attaaatatg ggaatgggag taagctacat tcccatgtat
     3961 attctatata aaatgctcta acgattttca cgttgtcaca tgaattgaat cgagttccaa
     4021 ctaaaatctg taggaaacta gccgcaggct gctcaaagca ctgctttgag gttgccggat
     4081 aagactgacg aagtcagctc aaaacaccgt tttgaggttg ccggataaga ctgacgaagt
     4141 cagtaacata tacctacggc aaggcgacgt tgacgtagtt tgaagagatt ttcgaagagt
     4201 attattcatc ttcgtcatca tcgaagcccg ctaacaggtc attaactttc acaatgcttt
     4261 ctgcagcacg gctcttgtag tccgcatctg cgcctgtaag gctcgcattg ataaattcaa
     4321 tcaccattgg aagattcatc cctgcgtaaa ggtcaatatc acgaccttcc atgatcaagc
     4381 gactcaccac attacaaggt gtcccaccga gaagatccgc aaagactagg aaatcatcca
     4441 atccttcaat aacagcttca aatttagcag taaattcttc tgggccatct tctggaagaa
     4501 gagctactgt gtaaatgttg tcttgtgggc ccataatcat ttctgtgcta cctctaagct
     4561 cctcacagaa gcgaccatgg ctcaccaaaa ttaatgattt agtcataagg aattacattc
     4621 caagtgcaaa gtgaccaagg gcagaaagag ccaaagcaag tacgataata ataccgatag
     4681 ctttagtaga gttcatacct ttcttaccaa gcaaccagaa gataaaggca gtaaagattg
     4741 ctggaagcaa acgtgggaag atttggttca agatgtcttg gaaatcaatc atcttttcac
     4801 cgattggcaa cttgtaagaa atttcaaagt taatcactgt tgctacaaga gcacccatca
     4861 tgaagacacc aagtacagat gcagcgtcaa tcaaagctgt caaggtactt tgcatgttgt
     4921 tgataaggtt aaccccttct ttgtaagcaa attccaactg tttccaacgg aagatgtcat
     4981 acgctactgc aactgcaatc caaaggaaga tcccccaagg ttggccagcg atagccatag
     5041 ttgctgcgac tgaccccatg atagcaggta caagtgaacc aaagattgta tccccaagag
     5101 gagcgaatgg tcccatcaaa cctgtcttga taccgttaac ggcgtctttt gaacctacac
     5161 catctttttc ttccatggca aggtcaaaac cagcgataat ggtatggaag aatggtgaag
     5221 tattgaagaa ttgagtatga actttcatca tttctttcaa ttcaggagtt ccatcaccat
     5281 acattttacg caactgaggc aagatcatgt aaaggtaacc agaagcttgc atacgttcgt
     5341 agttccaacc taattggaaa gtaaacaagc tacgtttgtt gatttgatta aaatcttctt
     5401 ttgtaagttt gtaattagaa ttcgtcatct tcgatttccc cactttctga tggtgtagaa
     5461 ggtgctgcta cagctacttt ttggctattt ttgaagtgaa gcactgcaag gaaaatacct
     5521 acgatagaaa taccaatcat agacaaacct ttgaagttgt tcacgaaacc aattttttca
     5581 gcaacttcag caggaagagt acctacgata ccagcaacag cgccaccaag acctgttaca
     5641 tatgagtaaa gaacagtcaa catagctgtc aaaccaaatc ccatagcaag gtagtgaagg
     5701 ttacgtttaa ctggaaggta acgaagcaag attgcaaatc caagacctgg aagcatacgt
     5761 cctgcaagtg tcaagccatc tgcaacccat ttgtaggctt caacgaagtc tactactgat
     5821 tgtacaaagg caccaccaaa agcaagggca aagaagactg gaagggcacg agatagagcc
     5881 cacggaatcg caccaagcaa gtagttgcgt tcaatacctt tatagtcaaa gcgttcgatt
     5941 gcagcatcca cacggtgagc gaagaaggta gtagtcatac gaccaagaac gtcgaagtaa
     6001 gtcaagagag ctgctactgg tacagcgatt gtagtaatgg caagcggtgc atcaattcct
     6061 tgtgaaacag agaaggctgt cgcaagaacc gcaccagaag ttgcgtcgat acgagaagca
     6121 ccaccgaagg taccaacccc aagaacgaac agttgcaagt taccaccgat aagtaaacca
     6181 gtagtcacat ctcccatgat taaaccagta atgaaaccag caaatacagg ggaacctgca
     6241 gatgaaacga tcgtcaactc atcacagatt tgataagctg agtacaaagt gagaagtaaa
     6301 atttgccacc attgtatcat aacaatgacc tcctaaaaat ttttttccta ttttaataag
     6361 ctcaaaaagt ctgaaattgg atcatttgga accatctgag cagtaagttt aacacctttt
     6421 tctgccagtt tgtggaagtc ttccacatcc ttgtctacta cgttgataga acgtgtaata
     6481 gaacgagttt ctggtgtttg agacatattc ccaacattaa gggtttcaag tggtacacct
     6541 gcttctacca aaccaaggaa gcggtctggt ttacgagcca cgataaagag acgttggcta
     6601 tcgtatttgc cagcaagaat attggctgca gctttctcaa ctggcaaaat actcaatttc
     6661 acacctggtg gtgtcgcaag tttcaaacca ctcttttcaa tatcgttgtt gacaacttcg
     6721 tcgtctacaa ccataatgcg tgaaacattt agttttccag cccaaagatt ggctacttgt
     6781 ccgtggatca aacgtccatc aatacggcat cctacaattg tcataagttt tcccccttta
     6841 tatgttttag tgtaggttta cgagttaaat gaatctcttc tttatattga ccttctgttt
     6901 caaagataat gatgcggttg gcaccttcct tgagatagct atgagggata taaagtgaga
     6961 gagttgggcc aacgttccaa aaacgtccta gattctgccc attgacaaag gcaaccccct
     7021 taccaaactc agacaagtct aggtaagtat cttttggctc ttcgactgta aagtcataag
     7081 cgtaaaaggc tggttgtcct tgagtccatc cttttgaaaa atcaattttc tcaggattgt
     7141 ctagtgggag tggatagtgt ttccagttta gtaagaaatg cagatcctta cagacccctg
     7201 tccgaattcc cttacgttgc gtatccgcta agaacttatg cccatagttg acacgcccca
     7261 tattttctat caagatatct aacctagata gccctttctt tttaccttga taaaaaaaat
     7321 cttccccaat ctctgtctga tattgagttt taacccactg accatcgaca tacagctggg
     7381 ccctatctcg accatcaatg atacgaagtc tttcttcttc tgcatcccag tttgtttctg
     7441 ttcgataaag taggtagcca taactttgtc ccagctcctc catcttttga ggatagagac
     7501 tttctacagg acttgacaag ctatctaagg tttcaaacaa agaaactttt tcaactagtg
     7561 gaatagcatc caactccata ctctctttgt agagtggttc caactgcgga tactctgaaa
     7621 aatgtgttgc catcatcttc ttgactgcaa gatatttagc agttggattt ccttcttcat
     7681 ccagaagggc atcgtaatca taagacgtaa cttgtggcag gtccaaagtt cctcgagctg
     7741 agcaaccatt catgaaacca aagtttgtac caccgtggaa catgtaaaga ttgatagagc
     7801 cttgttccaa aacctctcga actgcatctg ccaattcctt aggatcccgt gtgataatcg
     7861 gttctttcca gcgattgaac caaccatccc agaactccat acacatgagt ggccatttct
     7921 taccatgttc atcaaagaat tcctgcatct gcgaaaagtt gtaaggtgcc ttagaaccaa
     7981 agtttcctgt tacaaagagg tcctcttcaa ttaaggttcc agctttcaga gtagctcgcc
     8041 atggaccatc tgatgtaaag aggggacagg ttacgccaca ctcttccatt agctgtcgaa
     8101 tcgctctcag gtaagcctta tcttctccgt aagaaccata ctcattttca acctgcatca
     8161 tgagaatatt gccaccattg tccaacaaac gaggcaccag tcttggcaat aactgatcat
     8221 agtagcgacc aactgcctcg atatatgctg ggtcagatga gcgaattcgc atgttcttgg
     8281 tcaagagcca agctggtaag ccaccgaatt cccattccgc acagataaat ggagacggac
     8341 gcacaattgc gtagagaccc aaatcctgcg ctatttggag aaatttctct aaatccagat
     8401 caccttcaaa atgaaactca ccttcacgag gctcgtgtaa attccaagca acataagtct
     8461 ctaccgtatt aaaaccaaga gccttcaagt tatagagcga atgataccaa tcctctggag
     8521 gaaccctaaa ataatgaatg gcaccagata aaatcttaaa tgattttcca tcgagataga
     8581 aatcatctcg tatctcaaat cgtgtcataa aactaccttc cgaccgcgaa agtttgcgct
     8641 ttcatttgtt gttatattaa ttataaacca atctgtttga actgtcaata gaaattgtcg
     8701 ggatatttac tgcattttta ctattataca cacattcaat tagtttcaaa catttttaga
     8761 cccatttcaa acgctcttta aatttggaat ataggaccta aaataatttt gtatagaata
     8821 catttataaa atatgatcaa tccctatata gcttaatttt tcaaactatt attctaattt
     8881 tttattcaaa agactactat ttttttcgct tttatggtaa aattttctat ggagaaggaa
     8941 aatagaggta aaaatatggc aattcccaaa tatcaataca taaaagacga attaaaaaat
     9001 aaaatcatct ctgggcagtt tagcagtgga gataaatttt atactgaagc agaactcatt
     9061 tcaatgtacg atgtcagctc tatcacagtt gttcgcgcct taaacgacct tgccaaagat
     9121 ggctatattg tccgccaaca aggaaaagga accttcgttt cacgtgcacg caaacacaag
     9181 cttgtagagt tttcagatat tgaactcttc aatgctaaag atgataaggt aactgttctt
     9241 tcaattgaac gcggaaacaa gcttgtttac ctggaaaaat tgggtctacg cggcgatcaa
     9301 ttctactaca agattgaacg tatccgcgaa tcaaacggtg tcgtttatat ctaccataca
     9361 tcctacatcc cagaacaata tatcaacgca aattatccaa accttgaata ctatagttct
     9421 atctataatc gtttcaagtt agactaccac attcacatga atgatgaaca ctttgaagaa
     9481 atcaacgaaa tagtctttcc aactccagaa catgcggctt cagtcctcgg agtcgatgaa
     9541 caattcccta ctgtcctaca aactaaaatc accaaactcg aatcaactgg ccaagtttta
     9601 gaatacagtg aaacttacaa acgatctgat tactacaaga ttaaattcat ctcatgtgac
     9661 cgtgatcact aagaagaaag cctgagccta atcgctcggg ctttttctat gcttattata
     9721 ccacaccaaa aaggtagcgc ttacctattt ttggaagatt ctataatttg tggaatattt
     9781 tatagaaata gaaccaaaaa ttatactaga tatatatacg tattttttcc gaccaatctg
     9841 aaatcttaag cttaaatttt atattttttt atacttatta tagttttttg tcatctcctc
     9901 ttgactctcg ttaatataag aaataaaata aaggcgttga tttatataat cgctatcaat
     9961 ataacaatgc aatcaggagg ttttgcaatg aaacatgaaa aacaacagcg tttttctatt
    10021 cgtaaatacg ctgtaggagc agcttctgtt ctaattggat ttgccttcca agcacagact
    10081 gttgcagccg atggagttac tactactaca gaaaaccaac cgaccatcca tacagtttct
    10141 gattcccctc aatcatccga aaatcggact gaggaaacac ctaaagcaga gcttcaacca
    10201 gaagctccaa aaactgtaga aacagaaact ccagctactg ataaggtagc tagtcttcca
    10261 aaaacagaag aaaaaccaca agaggaagtt agttcaactc ctagtgataa agcagaggtg
    10321 gtaactcaaa cttctgctga aaaagaaact gctaataaaa aggcagaaga agctagccct
    10381 aaaaaggaag aagcgaaaga ggttgattct aaagagtcaa atacagacaa gactgacaag
    10441 gataaaccag ctaaaaaaga tgaagcgaaa gcagaggctg acaaaccgga aacagaggca
    10501 ggaaaggaac gtgctgcaac tgtaaatgaa aaactagcga aaaagaaaat tgtttctatt
    10561 gatgctggac gtaaatattt ctcaccagaa caactcaagg aaatcatcga taaagcgaaa
    10621 cattatggct acactgattt acacctatta gtcggaaatg atggactccg tttcatgttg
    10681 gacgatatga gcatcacagc taacggcaag acctatgcca gtgacgatgt caaacgcgcc
    10741 attgaaaaag gtacaaatga ttattacaac gatccaaacg gcaatcactt aacagaaagt
    10801 caaatgacag atctgattaa ctatgccaaa gataaaggta tcggtctcat tccgacagta
    10861 aatagtcctg gacacatgga tgcgattctc aatgccatga aagaattggg aatccaaaac
    10921 cctaacttta gctattttgg gaagaaatca gcccgtactg tcgatcttga caacgaacaa
    10981 gctgtcgctt ttacaaaagc ccttatcgac aagtatgctg cttatttcgc gaaaaagact
    11041 gaaatcttca acatcggact tgatgaatat gccaatgatg cgacagatgc taaaggttgg
    11101 agtgtgcttc aagctgataa atactatcca aacgaaggct accctgtaaa aggctatgaa
    11161 aaatttattg cctacgccaa tgacctcgct cgtattgtaa aatcgcacgg tctcaaacca
    11221 atggctttta acgacggtat ctactacaat agcgacacaa gctttggtag ttttgacaaa
    11281 gacatcatcg tttctatgtg gactggtggt tggggaggct acgatgtcgc ttcttctaaa
    11341 ctactagctg aaaaaggtca ccaaatcctt aataccaatg atgcttggta ctacgttctt
    11401 ggacgaaacg ctgatggcca aggctggtac aatctcgatc aggggctcaa tggtattaaa
    11461 aacacaccaa tcacttctgt accaaaaaca gaaggagctg atatcccaat catcggtggt
    11521 atggtagctg cttgggctga cactccatct gcacgttatt caccatcacg cctcttcaaa
    11581 ctcatgcgtc attttgcaaa tgccaacgct gaatacttcg cagctgatta tgaatctgca
    11641 gagcaagcac ttaacgaggt accaaaagac ctgaaccgtt atactgcaga aagcgtcacg
    11701 gccgtaaaag aagctgaaaa agctattcgc tctctcgata gcaaccttag ccgtgcccaa
    11761 caagatacga ttgatcaagc cattgctaaa cttcaagaaa ctgtcaacaa cttgaccctc
    11821 acgcctgaag ctctaaaaga agaagaagct aaacgtgagg ttgaaaaact tgccaaaaac
    11881 aaggtaatct caatcgatgc tggacgcaaa tactttactc tgaaccagct caaacgcatc
    11941 gtagacaagg ccagtgagct cggatattct gatgtccatc tccttctagg aaatgacgga
    12001 cttcgctttc tactcgatga tatgaccatt actgccaacg gaaaaaccta tgctagtgat
    12061 gacgttaaaa aagctattat cgaaggaact aaagcttact acgacgatcc aaacggtact
    12121 gcactaacac aggcagaagt aacagagcta attgaatacg ctaaatctaa ggacatcggt
    12181 ctcatcccag ctattaacag tccaggtcac atggatgcta tgctggttgc catggaaaaa
    12241 ttaggtatta aaaatcctca agcccacttt gataaagttt caaaaacaac tatggacttg
    12301 aaaaacgaag aagcgatgaa ctttgtaaaa gcccttatcg gtaaatacat ggacttcttt
    12361 gcaggtaaaa caaagatttt caactttggt actgacgaat acgccaacga tgcgactagt
    12421 gcccaaggct ggtactacct caagtggtat caactctatg gcaaatttgc cgaatatgcc
    12481 aacaccctcg cagctatggc caaagaaaga gggcttcaac caatggcctt caacgatggc
    12541 ttctactatg aagacaagga cgatgttcag tttgacaaag atgtcttgat ttcttactgg
    12601 tctaaaggct ggtggggata taacctcgca tcacctcaat acctagcaag caaaggctat
    12661 aaattcttga ataccaacgg tgactggtac tacattcttg gtcaaaaacc agaagatggt
    12721 ggtggtttcc tcaagaaagc tattgagaat actggaaaaa caccattcaa tcaactagct
    12781 tctaccaaat atcctgaagt agatcttcca acagtcggaa gtatgctttc aatctgggca
    12841 gatagaccaa gcgctgagta caaggaagag gaaatctttg aactcatgac tgcctttgca
    12901 gaccacaaca aagactactt ccgtgctaat tataatgctc tccgcgaaga attagctaaa
    12961 attcctacaa acttagaagg atatagtaaa gaaagtcttg aggcccttga cgcagctaaa
    13021 acagctctaa attacaacct caaccgtaat aaacaagctg agcttgacac acttgtagcc
    13081 aacctaaaag ccgctcttca aggcctcaaa ccagctgcaa ctcattcagg aagcctagat
    13141 gaaaatgaag tggctgccaa tgttgaaacc agaccagaac tcatcacaag aactgaagaa
    13201 attccatttg aagttatcaa gaaagaaaat cctaacctcc cagctggtca ggaaaatatt
    13261 atcacagcag gagtcaaagg tgaacgaact cattacatct ctgtactcac tgaaaatgga
    13321 aaaacaacag aaacagtcct tgatagccag gtaaccaaag aagttataaa ccaagtggtt
    13381 gaagttggcg ctcctgtaac tcacaagggt gatgaaagtg gtcttgcacc aactactgag
    13441 gtaaaaccta gactggatat ccaaaaagaa gaaattccat ttaccacagt gactcgtgaa
    13501 aatccactct tactcaaagg aaaaacacaa gtcattacta agggcgtcaa tggacatcgt
    13561 agcaacttct actctgtgag cacttctgcc gatggtaagg aagtgaaaac acttgtaaat
    13621 agtgtcgtag cacaggaagc cgttactcaa atagtcgaag tcggaactat ggtaacacat
    13681 gtaggcgatg aaaacggaca agccgctatt gctgaagaaa aaccaaaact agaaatccca
    13741 agccaaccag ctccatcaac tgctcctgct gaggaaagca aagctcttcc tcaagatcca
    13801 gctcctgtgg taacagagaa aaaacttcct gaaacaggaa ctcacgattc tgcaggacta
    13861 gtagtcgcag gactcatgtc cacactagca gcctatggac tcactaaaag aaaagaagac
    13921 taagtctttt cgataaaaaa taaacagcga gattgaagct cgctgtttat tttttaatta
    13981 atcacctagt ccaagacgtt caaagatatc atccactcgt ttggtgtaat aaactgggtt
    14041 gaagatttca tcgatttctt cttgagtgag acgtgatgtt acttctgaat ctgcctcaag
    14101 aagtggttta aagtctactt ggttgtccca agagtaggct gtttttggtt gcaccaagtc
    14161 ataggcttgc tcacgggtca tgcctttttc aatcaatgtc aacatagccc gttggctaaa
    14221 gataagacca aaagtcgagt tcatgtttcg gatcatattt tctgggaaga ctgtcaagtt
    14281 cttgacgata tttccaaaac ggttgagcat gtagtcaatc aaaatggtcg tatctggtgt
    14341 gatgatacgc tcagctgatg agtgagaaat atcgcgttcg tgccagagag cgacgttttc
    14401 ataagccgta atcatgtgac cacgaatgac acgcgccaga ccagtcatat tttcagaacc
    14461 gattgggttg cgtttgtgag gcattgctga agaccctttt tgccctttag caaagaactc
    14521 ttctacttcg cgttgctcag atttttgtag accacgaatc tcagtcgcca tacgttcgat
    14581 tgaagtcgca atgctggcaa gaaccgcaaa gtactcagcg tgaaggtcac gaggaaggac
    14641 ttgtgtagag atttcttggg cacggatgcc aagtttatcg cagacatact cctctacaaa
    14701 tggtgggata ttggcaaagt tcccaaccgc accagaaatc ttaccagctt ctacaccagc
    14761 agccgcatgc tcgaagcgct cgatattgcg tttcatttcg ctataccaag ttgccaattt
    14821 aagaccaaaa gttgtcggct cagcgtgcac accatgagta cgccccatca tgatggtgaa
    14881 cttgtgctcc ttggccttgt cagcgatgat attagtgaag ttttcaaggt cacgacggat
    14941 gatgtcgttg gcctgcttgt agaggtaacc ataggcagta tccaccacgt cggtagaagt
    15001 taacccatag tgaacccact tgcgctcttc accaagagtc tcagaaaccg cacgcgtgaa
    15061 agccaccaca tcgtggcgcg tctcctgctc aatttccaaa atacggtcga tgtcaaagtc
    15121 cgccttcttg cgaatcaaag ccacatcttc cttagggatt tcccccaact cagcccatgc
    15181 ctcgtcagag aggatttcca cctcaagcca agcacggtat ttattttctt cactccaaat
    15241 attcgccatc tcagggcgag agtaacggtt gatcatgtgt taatctttcc tttcttctta
    15301 agctgttggg aataagctat ctaggtaaac caagatttct actcaaactc ctcttttcca
    15361 ataaacacag acgggtaatg atctagtgta ttcaaatccg tatccagcgg tacatcatag
    15421 atagctaaat aattttcggg gtattgtgca gctagttctt catatttagc ttgtacctta
    15481 tcttggtcag cactagcata caacacttca acaactgctc cagtcttatc cttttcaata
    15541 aatgcattaa cgataatttg tatcatagac ttgtcctaaa aatcaatccc ttccccaaac
    15601 tcttccacac tatccggtac atcactaaac aaagtcacat gtcccatctt acgattatgc
    15661 tttgcttcta ttttaccata catgtggagg tgggtgcttg gattttctgt gacatatttt
    15721 tcagcggcct caacatgctg gccgagaacg ttaagcatga cggcaggcgc atgtagtttg
    15781 atggctggca atggtgctcc cagaacacct aatatatgcg tgtcaaattg tgaaaagtca
    15841 caggcttcaa tagagtagtg gcctgagttg tgtggtcgtg gagcaatctc attgacaatg
    15901 atgtcatcag ctgtcgcaaa catttccaca cagagagttc cagacaagtt gagttgttct
    15961 gcgattcgca ctgccatagc tttagccttg tctgctagac tttcagaaat acgggctggt
    16021 acgatggtct tagacaggat attgttgcgg tggatatttt cctgaactgg gaaaaacgtc
    16081 acctccttcc catttcctga cacgatgaca gaaatctcaa ggtcaaaatt gacaaattct
    16141 tccaagacac aagctgctga gtcggctaat gcataggctt cttccaaatc gtctgctgaa
    16201 cgaatgacat tttgcccgtg tccatcataa ccacctgttg cgatcttaag gacatagttt
    16261 ttcgacaagt cgatatctgc caagtctagg ctagaagtca cgaccttgta gggtgccaca
    16321 gtgacttgag ccttgtttga caaaaagtcc ttttcaaaaa tacgattttg cgaaatgcgg
    16381 agcagatctg ttccttgagg gagttgtcca tccttgataa cgacatccaa accgtcagcg
    16441 tcgacatttt caaactcgta agtgaggaca tcgcaacggt ctgccaactg acggagggcg
    16501 tccacatcgt tataaggtgc cacaatgatt tccgccacgc gagaggccgg gcaatccgcc
    16561 gcaggatcca gcgcgataac cttgtgcccc atgtagatag cagaaatggc catcatctga
    16621 cccagttgac cgccaccgat aattccgatt gttttagatg agctcatttg acgactcctc
    16681 tgcgattttt ccttgttctt ctgcgaaatc tgccaatgct gtcgcgatag actgatcctc
    16741 tactgagagg agacggagag cgaagagggc cgcatttgtc gcacctgctt caccgatagc
    16801 catggtcgca acaggcaccc cacccggcat ctgaacgata gaatagagtg aatccactcc
    16861 actaagagca cgagagttga ctggcacacc aatgactgga aggattgttt tagcagcgac
    16921 catacctggc aaatgggctg cgccaccagc acctgcgatg atgatcttga tgccacggct
    16981 acgggcttct tctgcatgtt tgaacatgag gtctggtgta cggtgtgcgg aaacaacttt
    17041 cttttcgtag gctacaccga agcggtctag gacttctgct gttttttgca tggttgccca
    17101 gtcggatttt gagcccatga tgatggaaat tactggtttc atttcttctc ctttttcctc
    17161 tttttcaaca atcaccttag cttgtgaggg acggcagcag ccaccaaagg tgtctcatgc
    17221 ctaaattgga aacccaaggt cttccaattt ccctgaacga ttggattatc atccaatcgt
    17281 tctttcacaa cggcggtaat tgctccatat tagctcgcta acgctcgcaa accatacgac
    17341 cattaacgta ttttgtgaat ttttattttt ctttttgata atggtcttag gtgatggagg
    17401 cggaagcaaa ccttcggttt cattcctaaa ctttgagcct aaggtctcaa agtttccccc
    17461 tgaccagaac attcactgtt ctggtctttt caccacgacg accattatcg tgtttggcga
    17521 ctgcgtcgcg ttattcttat atctttactt aattgccttg cttccgatat ctgttcggta
    17581 gaagagtcct tctatttttt gttgggatag ttcttggtag atgctggctt gggcttcttt
    17641 gacggtatct gctgtggtaa cgagcatata aactcgtccg ccgtttgaga gcagcgctct
    17701 gctattttcc gcaaacttag cccctgcata gtaggtaatg atgtcaccat cggttttgac
    17761 tggcaactca acaccctttg aataatctag cgggtagccc ttggatgcga caaccacacc
    17821 cagagtcaca cccttgtccg tccacgtgat atttggctcc ttgctatcca ggatatctgt
    17881 gatattttga gcaaagtcag aggtcaagcg aggcaagata atctgagttt ctggatctcc
    17941 gaaccgagcg ttgaactcga tgactttcgg tccatcagct gtcaggataa gccctgcgta
    18001 aagaactccc agataagggc gaccttcttt aatcatccct tctagaactg gcttgacaat
    18061 ggtgtcaacc gctgtatcaa ctacactctg tggtaagtgt ggaactggcg cataggcacc
    18121 cataccaccc gtgttaggcc ctttgtcgcc atcgtaggca cgtttgtggt cctgagccgt
    18181 tggcatgatg tagaacttat caccattgac aaaggcaaag agtgaaaatt cctctccttc
    18241 aaggaattcc tcaataacca cgcgcgcacc tgagtcacca aatttattgt ccaaaagcat
    18301 ctcatgagcg gcttcgaccg cttgctcaac cgtctcagca acgacgacac ccttcccaag
    18361 cgccaagcca tccgccttga ctacgatagg cgcaccatgc ttttcgatat aggcctttgc
    18421 ttcctcaaaa tctgaaaatg tgccataggc tgctgtcgaa acaccatatt tgaccatgat
    18481 ttccttggca aaatccttgg accactccag ctccgctgca gccctagtcg gaccaaaggc
    18541 cttaagccca gcttggttaa aatcatccac gataccagca gcaagggcat catctgggcc
    18601 gataaaggtc caagcaacat cattggtctt tgcgaagtca atcaatttag aatgttcgga
    18661 aatagagata tttaccaatt ccaaaccatc cagagtcatc ccatcattcc caggagctac
    18721 aaagactttt tccacgtctt ttgattcaag taacttttta gcaatcgcat gctcacgacc
    18781 accagaaccg acaacaagca gtttcattcc tcaacctctt ttgcgaatta tttaccaaca
    18841 ttatatcaaa aaagttcgtt ttaatcttgt ttcagttagc attttaagcc aaaaaaggaa
    18901 agaaactgtt ttcttccctt ttatcttctt aatgtctaaa atgtctcact cctgtgaaga
    18961 ccatggtcaa gccatacttg tcagcggctt cgatagattc ttggtcacgg actgagccac
    19021 cgggctggat gatggcctta attcctgctt tggcgatttc ttccacgtta tccgcaaatg
    19081 ggaagaaggc atctgaagca aggaccgccc cgtccagacg atctttggct tggtcaatgg
    19141 caaggcgaac agaagccaca cggttggttt gacctggacc aacaccaagt gtcatgtggt
    19201 cgttggtcac gataatgcca tttgatttga cgtacttgat agccttccaa gcgaactcaa
    19261 gagcagtcgc ttctgtctcg gttggctgac gtttggtcac cacttgccag tcagctgggc
    19321 tttccttgac cacgtcttga ttttgcacga gaagtccacc gactacacct gtgtattctg
    19381 cttccacttc gctagcctct tgagcattaa atggcaaggc aaggatacgc aagtttttct
    19441 ttttattgat caaaatggct agcgcttcat ccgtatagct tggtgcaatg atgatttcga
    19501 ggaaaacgcc gtgcatcttc tcagctgtcg cagcatccac ctcacggttg aggacgacaa
    19561 ttccaccaaa gatagacact gggtcagact cataagcgta ttcccaagca gtctcgatgt
    19621 catcagcttg accaattcca catggattca tgtgtttgag agccacaacg gttggactat
    19681 ctttgaagtc acggatgata cggatagcag catctgcatc acggatatta ttaaatgaca
    19741 attctttccc gttgagctgt ttggctgaag caatggagta atctgtaggc aaagctttct
    19801 ggtaaaagtc cgcgtcttgt tgaggattct caccgtaacg cattggttgc ttgaggtcat
    19861 aagtcaaagt gagtttttca ggcttgcttt cacccacttg agctgtgaag tattttgcaa
    19921 tcaaggcgtc ataagccgct gtgtgacgaa atactttggc tgctaaacgt tggcgagttt
    19981 cataagaggt ttcgccgttt gctgccaatt cgtccaaaac cacagcgtag tcagcaggat
    20041 ctaccacaac tgtaacactg gcatgatttt tcgctgctga acgaagcata gatggcccac
    20101 caatatcgat attttcaact gcatcagcat aagtcacatc tggtttaagg atagtttcct
    20161 taaatgggta aaggttgacc accacaaggt caatgagctc aatcttgttg tccttagccg
    20221 cttccaagtg gctatccaag tcacgacgag cgagaagccc tccgtggata tttgggtgga
    20281 gggtcttcac acgaccgtcc atcatttctg ggaaaccagt cacatcatcg atagcaatgg
    20341 tatccacccc agcattatca agggcaacct tagttccacc tgttgagata atctcccaac
    20401 caagtttttt gagttcttgg gcaaattcaa caatgcccgc tttgtctgag acgctgatta
    20461 agacgcgttt agtcattata ttctcctttt taatcattag ttaaacacca attaaatgca
    20521 gtaacagtaa aacaagataa gcaaaaccaa ggctaagcat acctaagata ttgatccatt
    20581 ttctagtctg tgatttgaac actcttataa aaatttgata aatcagtaag cctacacaga
    20641 cacctagcgt atttaaagtc aaatccgtta tatctgttat acctattgct aaaatatact
    20701 gtaagcactc aaacaataaa ctaatcaaga aacctgtccc gactattctt aaactagata
    20761 aattagtttt tatcaaaggg aaacaaacac ctaatggaat aaaggaaatc agattaaata
    20821 acatttcagc aaaaacaatt tttccatcga ctattagtgg ttctgaaaat ggaatccaat
    20881 tgatatacct tggagctaag aaaaatgcta taaattcagg atttgtttca aacttaaata
    20941 agattcccca agttaataac atcagataga cataaaatac atatcgagtt gtttttttag
    21001 attctaacat tacaaatacc tccgtttgaa gccgtcttca acaaacactg actccaattt
    21061 aaaatcaaag atatcatatg aatcatcaaa aagtcaatct gtaaatagag ccttcactac
    21121 ttccagatac aacctgtact ctgcttcatg gatgcgagct tcaaatctgt caatggtatc
    21181 atcagctagt cgtggcacac gaacctgttt gatgacctgg cctgtatcca cacccgaatc
    21241 cacccagtga atggtcacac cagactgacc cacgccagca ttccaagcat cctcaatccc
    21301 atgagctcct ggaaattctg gcaagtaggc tggatgaata ttgacaatcc gaccttcata
    21361 agccgacaat aaggttggtc caacgatttt tatgtagcct gctaggcaaa ccaagtcaat
    21421 ctggtgttct tccaagagtt cgacaagggc tgcttcgtag tctgccttgc tctcaaactc
    21481 cttgagttca aaagcatagg acagaacgcc gagctgcttt gcacgctcaa gcacataggc
    21541 atcacgatgg tctgaaaaga caaactccac tggaaattct tcggcaatca cctgaaaatt
    21601 tgagccatta ccagaggcaa aaaccgctat ttttttcatt tgataatgac actttcgttt
    21661 tctttcttga cgatgcgacc aatttcatag actgcttcat ccaacaattc ttttacacgc
    21721 tctacatttt cagggctgac cgccaacata agtcccacac ccatattgaa gatttcaaac
    21781 atttcttcgt gtttaatctg accatatttt tcaagggctt tgaaaattgg aagcactgga
    21841 actttgcttt catcaatttc agcagctagg tcatctgcaa acatacgagg gacattttcg
    21901 ataaagccac cacctgtgat gtgggcaatg ccgttgacca actcttcttt gatgagcggc
    21961 aagacagcct tgacatagat acgagtcggc tcaagtagaa cttccttaag tttcttgcct
    22021 tccaattctg gtaggacttc ctcacctgtg taatccgcaa agacacgacg aaccaaagag
    22081 taaccatttg agtgaatccc acttgaagca agtccgagaa gaacatctcc ctctaccacc
    22141 tttgaaccgt caatgatttg agatttttca gccacaccga ccgcaaaacc agccaagtca
    22201 tagtcgtctt cgccgtacat gcccggcatt tcagccgttt ccccaccgat gagggcagca
    22261 ccagcctgca cacaaccttc tgccacacca gcaaccactt gttctagctt agctggttca
    22321 ttcttccctg tcgctacgta gtcgagaaaa tagaggggtt ccgcacctgc agcaatgatg
    22381 tcgttgacac acatggccac acagtcctgc ccgatggtat cgtgcttgtc gtacttgata
    22441 gccaacatga gcttggttcc gacaccgtca gtccctgaaa tcaagacggg ttctttaacc
    22501 ccagtcttgg aaagatcaaa cataccacca aagccaccaa gagctcccat gacacctgca
    22561 ctctccgtac gggccacgtg ctttttaatc cgttcaacaa cttcataacc cgcttcaaca
    22621 tccacacccg actgggcata tgcattttta tttgtcattt attttttcct tttctttaat
    22681 ggagaatctg tcgcctactt gtaaaaactg gtcttttctt ccaaacttct acgatagtct
    22741 tcttcgtagt catagagagg cgttgggtag tcaccgtcaa agtaagcgac acagagacca
    22801 ccgttcggcg catctgtttc gataccaatc gactcaatca agccatcaat tgaaagataa
    22861 gtcagactgt ccgcaccaat gatttggcga gtttcttcga ccgtatgatt ggctgcaatc
    22921 agctcctgac gggtctggat atcaatcccg tagaaacatg gatacgctag tgcaggactt
    22981 ccaatggcaa cgtgaacctc agtcgcaccc gcttctttca agagctgaac gatacgacga
    23041 gaggttgttc cacgtacaat ggaatcatcc accatgacca cacgtttgcc tttgacaaca
    23101 cccgaaacag cagacagttt catccgcact ccttgctccc gcaattcttg agtcggttgg
    23161 ataaaagttc gctgggtgta ttggtttttg atcagaccca tttcatttgg taagcctgat
    23221 tcttccgcaa atcccatagc cgcgcttagg gaagaattgg gcacaccaac tacaatatct
    23281 gcctcatgct taaattctcg cgccaattgc gctcccattc tcttacgtgc cgtatggaca
    23341 ttgacaccgt ggatattaga atcagggcgg gcaaagtaga tatactccat agaacaaatc
    23401 gccaactggg tatcatctgt atagctgtca tactgaatgc cctcgtcatc aatgatcaca
    23461 atctcacctg gcttcaaatc acaaatccac tcggcaccaa tgacctcaaa agcacaggtt
    23521 tcagaggaaa caaccaccgc tccgttggcc attttcccga tagaaagcgg acgaaagcca
    23581 ttagggtcaa gagccgcaat caacttgtcc tcaaacagca agatataggc aaaaccacct
    23641 ttgacaaggc tgagcgcttc cttgattttg cccatcaggc taggattatg actgcgacga
    23701 atgaggtgag ccaagatttc agagtccgaa gtcgcgctga aaattgctcc tctttgttcc
    23761 agttctttct tgagagaggc tgcattggtc agatttccat tatgagccaa accaaactgc
    23821 atatcgtgaa aacggaagag gaagggttgg atgttatcaa cagaagcttc gccagcagtc
    23881 gcataacgca catgcccaat cgcaccagct cctgtcaatt tatccaaatt agatggattt
    23941 ctgaaaactt ctgataaaag ccccatgtca cgatggcgct tcagttgtcc ttgatcgttg
    24001 gagaggattc ctgccccctc ctgaccacgg tgttgaagac tgtggagtcc aaagtaggtc
    24061 aacttagcag catctggatg tccccaaata ccgaaaacac cacattcttc attaagagat
    24121 tttacttcgt atgtcatttt ttatacctaa ttttcatttg taatcatcaa gagctagatt
    24181 tacatgactt ttacattact gatactatct attagaaaat ctgtaagtct tattttccag
    24241 tgaaatgttt aaccgctgat gcgaacaggt gttggtcttt attgcctggg atattttgga
    24301 aaagaccatc ctcataacgt tctgagtggc ccatcttacc gatgatttga ccattcttgc
    24361 tggtaattcc ttcgatggca tggacagaac cattcggatt gtacttagaa tccatacttg
    24421 gtttaccgtt aaagtcaacg tattggctga aaatttgtcc attgtcacgg agctctgcaa
    24481 attcctcagc cgtcacgaca aacttccctt caccgtgcga aacaggaata gcgtggatat
    24541 cgcccacttg cacaccagcc aaccatggtg agttggtatt ggcaatgcga gtttccacca
    24601 tcttggccac gtgttggttg gcatcattgt agaagagggt tggactagta ctgttagcat
    24661 cttcaaagtt tccgtatggt aggagacccg atttgactaa ggcttggaat ccattacaaa
    24721 taccgataat caagccacca cgggcgataa agctatcaat agccacacgc actttttcat
    24781 taagcaggat attgacgata aacttagctg aaccatctgg ttcatccgca gccgagaatc
    24841 caccggcaaa gaagagaata ttagtcttgt cgatattgtc aaccatagtt tcaactgact
    24901 tgacaatagc ttcttcattc aaggtcacga atggcaccaa attgacctct gcaccttctt
    24961 tttcgaaggc cttagctgaa tcatattctg agttggttcc tggaaagact gggatgtaaa
    25021 ccacaggttt ttcaaccttt tctttggctt taatcacaac atctgatgcc acagctggta
    25081 cttcttctag ttctttcgct tgggtaaatt ctgttgggta aacttcttcc aatgtccctt
    25141 gaaatgcact gtcaagcttg tgtccatcta gcttcacacc gttgacagtc agtgtaaagt
    25201 ctgctttcgt ttgtccaatc ttctctactc cagcaatttc ttcaggagat gtgaagacaa
    25261 agccgcctaa ttgagctgtc aaagctgttt taagttcagg caaggtcacc tctgcaccaa
    25321 tatagtttcc aaaggtagca agagccaaac tttcaactac accaccgtat ttgacagctg
    25381 atgcagatgt cactttatgg tcagcttggc ttgcttcaaa ctgagcaaaa tttttcttaa
    25441 tcaagtcaaa atcaatctct gcagagaggg cttgacctgg gatgtagtag atattttccc
    25501 caacagcttt aaattctgga gagagcacct tacggctatc tgccgtcgtc accccaaagg
    25561 caaccaaggt tggcggaacg gtcaattctt caaaggtacc agacatggag tccttaccac
    25621 cgatagatgg caagccaagt tgaatctgag cttcaataga gcctagaagg gcggctactg
    25681 gctgaccaaa acgctctgct tgcttgtcca tccgctcgaa atattcttgg taagagaaac
    25741 gagccttaga ccagttggca ccagcagcca ccaaacgagc agttgcttcg ataaccgcat
    25801 aagcagcacc gtggtatgga gaccattcag ctacatatga gttgaaacct tgagcaatga
    25861 ccgacgcagt atgagtcaca ccgtgttgaa ctggcaattt ctgcacagat gcctcagttg
    25921 gtgtgagttg gtaacgacca ccaagtgggt gattaaccgt tgagcgtcca acagagcagt
    25981 caaagacagt ctgtaatcct ttttgacttg catggttgag gtcagataga accgtaaggg
    26041 tatctgattc cagtgtttca gcagatgttt gacgctcttc tgggagtttg acatccttgt
    26101 ccacaacttt ggcatcgaca accacgcgca caccattggt gtcaaggaaa cgacgctcca
    26161 agtcaacgat tgtctcacca ttccagttca tgacaagatt tggtttttca gttactgtcg
    26221 ccaccacaac agcatcaata ttttctttgt tacattcggc aacgaaggca tccacatctt
    26281 caggacgaac cacgaccgcc atccgttctt gtgattcaga gatggcaatt tctgtaccat
    26341 tcaagccctg gtatttaaga ggcaccttgt tgaggtcgat ttcaagaccg tctgccaatt
    26401 caccgatagc cacacagacg ccgcctgccc caaagtcatt ggacttcttg atcagacgag
    26461 tgacattgcc attacggaag aggcgctgaa tcttgcgttc ttcgatggca tttccttttt
    26521 gaacctcagc accagcagtc tctacagact caactgtttg aaccttagaa gagcccgtcg
    26581 caccaccgac accatcacga cctgttttgc ctccgagaag gatgatcaca tcacctgctt
    26641 caggtttttc acggacaaca ttgcccttgg gagccgcacc aacaacggca ccaagttcca
    26701 tacgtttagc tacaaagcct gggtggaagt attcacgaac gtaggttgtg gcaagcccaa
    26761 tctggttacc atatgaagaa taaccatgag ctgctgtttt agaaatgact tgttgtggca
    26821 atttcccagc acgagtttcc gaaatcggtg ctgtaatatc accagcacct gaaatacgca
    26881 tggcttggta aacataggaa cggcctgaca acggatcacg aatagctcca ccgatacagg
    26941 tagccgctcc accaaatggc tcaatttctg ttggatggtt gtgggtttca tttttaaaca
    27001 tgaggagcca aggttccttg acaccatcaa cgtccacttc aatttcaact gagcaggcat
    27061 tgatttcgtc agagacttcc atatcatcca atcgtccatt agcacgctca taacgaccga
    27121 aaatagtcgc catatccatc aaggtttgtg gtttttcaga ccgacctaat tcctcgcgca
    27181 tggcaatata cttgtcatag gttgactgca attgcttttg aaatttagaa gctgaaaagt
    27241 cgatgtgttt caactctgtc tcaaaagtcg tatgacggca gtggtcagac cagtaagtgt
    27301 ccaaaacctt gagttcagtc tcagttggca cgcgcccgat tgacttaaag tagtcttgga
    27361 taaagagcaa atcatccact tccatggcca tcccttgttc ggccttgtag cgagcaaagt
    27421 cttctgctgt atagctttca aagaaagtca attttggaat ggtcttgtct gactctgaaa
    27481 actcctgctt ggcaatccct gtcgtgatat ccttgaaacg agaatcaact ggattgagca
    27541 ggtagttttt gacagcttcc aactcagtca catcaatatc tttattcacc aagtaaagtt
    27601 gggctgtgtt gactgtcacg tcactcgaac ttcccaacaa aagcaaggct tcctgtgacg
    27661 aagctgcacg ctggtcaaac tgccctggta gactttcaat ggcaaagaaa gcatagttag
    27721 caagatccgc ctgcacagat acttcatcta aaacatggtc ggttacctgc tcagagaaaa
    27781 tgtgcttctc tgcaggtgca aacaagtcct cagccaagtc aaatacatca tatacttgca
    27841 caatacgaat acttttcaag cttgacagtc ccaagttgtg ctggagctct ctaaccaaac
    27901 tctctgactt gacctgaaaa tcagcctttt tttcaacaaa aatacgttta tccatcaatt
    27961 cttattcctt tatttcagct cttgcaatat tcccaaacag ccttgaggtt gttattttaa
    28021 accctgcaac ttttcctaga caatttcgta aacatcggtt agttcaccta gttctctaca
    28081 gagtgaaaag gtctggggga ccttttcagc ctgagtcctt ttagttgaga gacgaaggtt
    28141 ttccattgca aacagattat ttcaattcct gcaacttttc ccaaacaatc tcataaacgt
    28201 cggttagttc tcccaatcct ctacggaaaa catccttatc catgtggttg ccatcagcat
    28261 cccacaagcg gcagttatct ggtgaaaatt cgtctgccaa gataatcttg ccatccttgt
    28321 caaaaccgaa ctctagctta aagtcaatca atttaagccc aatctcagca aaccagactt
    28381 tcaatagttc attgatacga cgcgtttctt ccttcaagta ggcaatctgc tggtcatccg
    28441 caatctgtag gaatttcaca tgctcatcat tgataaatgg atcatccaaa tcatcatttt
    28501 tgtagtaaaa ttcgacaatc ggagtctcca aggcgattcc ttcatccaca ccaaaacgtt
    28561 ttgaaaagga accagcagta tagttgcgga gcacgacttc caaaggaata atcttaacct
    28621 ttttattgag ttgttccgtg tctgaaagtt tctccacaaa gtgagtcgcc acaccagccg
    28681 catttaattt ctcaaaaata aaagatgaga tctgattatt caagactccc ttacctgcaa
    28741 tctgctcctt cttgacacca ttgaaagcag tcgcctggtc cttgtaagtt gaaataataa
    28801 gattttcatc ctcagttgta tagatatctt tagcttttcc cgaatagatc aattgttttg
    28861 acattttaaa gttcgccttt cgtattactt gagcacattt taccacaaaa aaccaaaaaa
    28921 cacaagaatt taaccgaata aatagtagat atttttcaaa aattgtaaag aaaaaactgc
    28981 aagaagaatc tttctcacag tttaaaaatt atttaactct aaaaacacga acattactct
    29041 ttgttcaaaa attgatccaa ataataacgt agataacttt tcttgcccgt aatcatctgc
    29101 aagcggcctt ccaccccgta cctaagtttt tcagcctgct ccgaagttag attagtctcc
    29161 gcctcgattt taaagaaatt ccctttctca gtcttagtag ctgtcgcatc aatacttgta
    29221 atagtagaat ctaggaaaag ttgattcccg gcatcatgag tcgtagtata gcgaacagaa
    29281 tcaccgacct tgattcttgc tacatctttt gaacttagat aggctgtgag tttggctttc
    29341 ccttctcttt ccaaagatgg ataaagttgg gctagtaggg caccttctgc aaccatgcta
    29401 gaatcactgg tctcaggatt aagatgaagc accccatcct cactcgccgt aattttcccc
    29461 ttgtctaaaa gatttccctg taccttctta cctgactctg cctccaagat tttctgggct
    29521 agaagggtca attcctgacc aacctttgcc aagtgttggg atttaaggga ttccaattga
    29581 ctgcttaacc ctgacgcata ggcttgctgg gtacctgaac ctgcatactg gacacggtaa
    29641 gtagcaagac tagattctaa ctgagaaatc tgtgcttcaa cctgtgcaac tgcctgaacc
    29701 ttagtttggg gattttcctc gccctgagac ttgtaggact ggtaaaaaga gtaggctaga
    29761 ttctgaccgg ccaaggaagc acctgtttca atagctgact tagctgtctg gtaatcgcga
    29821 attttagcct ctgtttgact gatgaggttg ccgatttcgg cttgggtttg gctagctgct
    29881 gcattctggg acgcgatggt ctcattttgt tgcgatgtac tagccctaag actgcctgct
    29941 tgactgatgt agtcgcgaaa ggtggcttgg tagccaaact tatcctcctc tggaaagtgg
    30001 ttctcccctt cttgcaggct cttttgcaga tactccaatt gctttttttg atcctttagc
    30061 atgtccaact gactggcata ggactccgct tggacaccct ctgccccttc ttggtattga
    30121 accaaaagat cccccttctt aaccagctta ttttcttcca aatgattgac aagaatacga
    30181 ttgttgctag ttgactggat atttgcaaga atacgactag gttcgacagt agctctagtg
    30241 gacaaactca tctccttctc tgcaacagtt gcaaagccaa gtaaaaacac gagcagaagg
    30301 gccatgggta caatcacact actggaaaaa ttatggtaac gacgattata aaactccgca
    30361 ctttctaaaa attctggttt catcctctcc tctttctagc tattgaccaa atgggcgtaa
    30421 aagccaccct gtgcaagcaa atcagcatgc tttccttctt cgacaatctt gccctgatcc
    30481 aagacaacta ccttctctgt ccgctcagca atagtcaagc ggtgagcaat gaaaatcaag
    30541 gtcttgtcca aagccatgag attatcgaca atccgcttct ctgtcaaaat atccaaactg
    30601 ctagtcgcct catccaaaat caagaccggc gcatctgtca agagagcacg cgccaaagcg
    30661 attctctgac gttgaccacc tgaaatccct gccccatccg aagtcaattc tgtctggtaa
    30721 ttcagtggca tgcgctcgat atcctctcga atctctgcca attcgaccgc ccgtaagata
    30781 tcttcctgtg tcgtcccctc cttggctccc aaaagaagat tctccaaaat cgttccgtta
    30841 aagacatagg gctgttgagg cagatagttg atgtactggc gcagggcttt tttatcaatc
    30901 tgattgagat tgacaccacc cagactaatc tccccttgac ttgggtcgta aaaattaacc
    30961 atcatcttgg ccaaagtcgt cttacctgac cctgaaatcc ccacaaaagc caccttagac
    31021 ccttggggaa cggttaaatt gatatccgac aagacgtctc gaccatagcc atacttgtaa
    31081 tgaacctgct tgaaggtcat ctctcccttc atcaagctca aatcctcaac tgttttcttc
    31141 tcctcaaact cagaagctac tagatacact tcatttagac ggttattggc aacctgcgct
    31201 gtctgaagct tggtttgcag attgatgata ttttccaaag gattggtaaa gtaaaccagc
    31261 aaggtattat aggtaatcaa ctgccccaaa ctcatcttgc catccatgac cagaacagcc
    31321 cccatccaga gaatgccgac attaagcaag agatgggcaa cctttttcag agccttttgc
    31381 tgactctctg ctcgactata ggtaaaggat ttcttcagat aatccacaaa ttccttgtca
    31441 attttttggt aacgctgact ttcactggtc aaggacttga tagtctcaat accgttgatg
    31501 tcctcaatga tagaagaaga cagaaccgca ttggcttcca tggtatcccg attcatcttt
    31561 tcaaacggct tcataaaggc aaagataatc actgtgtaga taggaagcgc caataaagtc
    31621 atgaaaaaga gattggtatt ttgtgaaaat agaacaaggg aaataatgac aaccgttgac
    31681 acatctagga aaatcgaaag gatggtcgaa gccagcgcat cgatgatact gttagcatct
    31741 gtaaaacgag acacgatctc ccctgtcctg cgtgtcgcaa agaaggacat agggaggtga
    31801 aaaacatgct tgatatagga caaaatcacg tcaatcgaca agcgttgccc caaaacaagc
    31861 aagagatact cctgagcgta agacaagatt tgctggagga tgtagacgat gactagccca
    31921 atagaaataa tccctagtgt cgaacgcatc tgatctggca cataggtatc aatgatagac
    31981 tgcagataat aagaacccac aatgttaatc ccggttacca agagtgttgc caaaacgata
    32041 ttggcaatca agccacgctg cttcactaat atagggataa aagagagcag accatttttt
    32101 tgttccttat aaggcttata gtctggacta ggtgccataa aaagagtcac tcctgtccat
    32161 tcttcctcaa aacgctcacg tggcagttta gtcaacttca ccccgggatc tggatcggca
    32221 atatgaatgc tatccttatc ctgcccagtc accacatagt agtggagcaa tttcccttcc
    32281 ttaagcacat gggcaacaaa aggaaaagtc aaatccggca agtcaaaaag cgtcatatcc
    32341 gccttaatgg ctcgcgtctc aaaaccaatc tcctctgcca ccttgaccaa gcccaaagcc
    32401 gtcgtcccat ccatggtcgt cttagccaat tctcgcaagt gagccaaaaa ataataacta
    32461 ccatagtagc caaaaaccat ggctaatgaa gctacaccgc agtccatctg atccacttgc
    32521 ggacgatagt gacgtttccc aaatttcata ttcatctcct tttccctaat actcaatgaa
    32581 aatcaaagag caaactagga aactagccgc aggctgctca aaacactgtt ttgaggttgt
    32641 agataggact gacgaagtca gtcacatata tacggcaagg cgacgttgac gtggtttgaa
    32701 tttgattttc gaagagtata aactcatctg ataacaacta tcttacccca atcactaaac
    32761 aaaaactgga cttccttccc aaatgagcct atctccctcc caactgcact ttttggataa
    32821 aaaaataggc agaacaagag tactgcccac taaaaatatg ctattgaaag gaaattgatt
    32881 ttttactgtc accctagaca agcttgaaac aaataaatca ttgatagtaa cacttacgac
    32941 atcctattta ttacttcaat ttctaatgtc tctgctattt ctaagctacc tctggtatga
    33001 tctattccta gtcagaatag ataacaccgt tctaaattac gattcatagt tactcctttt
    33061 ttgactcgtt actataagac tcctatttac atgcgcaaaa taattttgat tcagattcat
    33121 catttatagt tttgattatt ttttaacaga tttttctgtt ttcttctccg aagactttaa
    33181 aaattttttt ctaattaaat catccatata aggaccaaat ataccaacta ctaaaccaat
    33241 aataaaactt ttaaaatcca taattaccac caacatgtcg ctgcataggc cacacctcca
    33301 agtatagctc ctcccgcagc accagttgct gcaccttgcc atgttcttgt tttaattcct
    33361 agctgaagac ctcgtactgc tcctcctcca acacctgctt tggcaaaatc tccccaattg
    33421 catccgccac cttcaacgca agcaagcatc tcagtatcca taatttcaaa ttgtgacatc
    33481 ttttttgtat tcataacgaa tacctctttt ttatttttaa tatttgtctt gttacaaact
    33541 tgacaagttt agtataacag tatctattaa tttttttcat ccaaatcttg aattggcata
    33601 gaaacgtctt gaattagctt ttttgtttca aaatcatctc tatttttaaa aaagatgttt
    33661 tctaatcact tttttactat tagacttcct gcaaaactag aatcctagtt catgattgat
    33721 aataccagca atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt
    33781 tgaaaacatt ttaaacgttt ttactttggc aaagatattc tcaaccttgc ttctctcctt
    33841 agatagcgca tgattacagg ctttatcttc aactgttagc ggcttgagtt tgctggattt
    33901 acgtggagtt tgtgcttgag gatatatctt catgagccct tgataaccac tgtcagccaa
    33961 gattttacca gcttgtccga tatttctcat ttctaaaaac catctacttc cgttgacttg
    34021 gaactccgat tgctattttc cttgaatgat tttaaccaca tctcctacgt tttggagttg
    34081 gtcaatttct tcatcgctga tttcgatact aaattcatct tccagagtca agataaactc
    34141 catcaagtca acagaatccg catccaaatc gtctttcaga ctcaaggatt ctgtcacgac
    34201 aaagtcctct ccctgtcgct cttggataat ggtcacaata cggtcaaaaa tttctttttc
    34261 tgtcatctct tttattctcc tgaaaattca cgcgcagtct gggcaaccac gtctgtttct
    34321 agcatggtac ggatctgacg aatcgtacta taaacagcct tggcatcgct tgagccatga
    34381 gtcttgacaa caggtgcctt aacaccaaac aagaccgctc caccaatatc tgaataattg
    34441 agttgttttt tcaaacctct gaggctgtcc ttgagaagga gggcacctag tttcgctcga
    34501 agaccaccac ctgtaatagc tgtcttgagc aagcccatga ttcccatagc tgtcccttcg
    34561 atggatttga gcacagcgtt tcccgtgaaa ccatctgcca caacaacatc tgcaacgcca
    34621 ttcatcaaat cacgcgcttc cacatttccg ataaagttca aactttcatc agccactagt
    34681 aattcataag tttccttacg aagcggatcg cccttgctac tctctgttcc gttattgagc
    34741 aagccaacac gtggttgcgc aatgccacga acatttttag catagaagga tcctagaacc
    34801 gcgtattgat ggaggtgctg ggctgtattt tccgcattgg caccgaggtc tagcatgtca
    34861 aatcccttcc catctacagt cggcaaagtc gacataagcc caggacggtc gatattcttg
    34921 atacgaccca cgatgaagaa tccagcagcc aacaaggcac ctgtattccc agccgaaagg
    34981 acagcgtctg cttcaccatc tttgacagcc ttggctgcca ataccatact ggcatttttc
    35041 ttattcctaa tagctctcgt aggttcatca tccgaatcaa tcttctcatc cgtatggata
    35101 atgctgacgc gctctgtcgc tgtcagatat tgcttgattt tagcttcatc tccgtaaagt
    35161 tgaacctcga tatctgaaaa gtcagatagg gcttgattga caccctcaac aatggcctga
    35221 ggtgcgtaat cgccccccat ggcatctact gcgatttttt tcatttcttt tcctctttta
    35281 gtaattgtcc ccagtctgct agggaatcaa taaatttctt tgattttagg tgaatcccaa
    35341 cgtactcttc atataattga tccataaatt ggcgtagctc ttgcttgatt ccaggcttga
    35401 gcgaaatggt ctccaaagtc tcaaaatcaa tagcttgaaa ttgattgagc agatagggga
    35461 tattgggatt gagatgacaa cgtctcttat cctcatgata atgctctgga cagaggcagg
    35521 ctccatattt gaaagaaaag tcaaaagcct gaccaacccg atggcagaag acacactcat
    35581 taaaattgag gctgattcca aatcgagtca aaatttgaat ttcaaaaata ttggtcaaaa
    35641 cctgataatc caagcctgct tccatcaact ccaaagtctt ttgcaaaaaa gcaaacaagg
    35701 gagcatcctg ctgattgtcc tgcaaactag catctgcaag agctgccaca taggtcgcat
    35761 aggccatgac aaagaggtca ctattaatct tgggaaaagt catgacctca tgatagtctt
    35821 cgatgtaact gagtccgtca tcattgattc gcaagagaaa tcgtgccagc accaagggct
    35881 gaataacagg cgccagctta gactgaccag cgtgtttgac aaaaaacatg cgtttgccaa
    35941 cctgctctgt aaaaattttg acgagcttgt catcctcacg aaaattgcga ttgtaaagca
    36001 ccaagccttg actcgtgata gactgaatca tgcttctctc atgtactcct caagtcgttt
    36061 catggcttct ttgatagtct ccatgctggc tgcataagat aggcggacgt agccttcccc
    36121 gtaacgtcca aaggctgcac cagggataaa ggcaacggcc ttcttctgag caaaatcctt
    36181 cagaaaagca aaggagtctt gattgtagcc cgctggaatt ttagcaaaaa tatagaaggc
    36241 accgtctggt ttgataatct caaaaccaag agcagtcatt ttttcgatga tatagtcccg
    36301 acgttggata tattccttct tcatgggctc cgcatcgttt ttaccagccg tcaaggcttc
    36361 taccgcagca tgttgcgcca tggtatttgc ggcagtgacc aagtactggt gactcttgat
    36421 taactgggct gtgaaggtcg caggagcgaa aatcagcccc aaacgccaac ctgtcatggc
    36481 atgcgattta gacaaaccat tgataataat agtctggtct ctcaacatcg ttcctagaga
    36541 cacatgggct tcgcctgtgt aggtcaattc tgagtaaacc tcatcacaga caacaaaaat
    36601 ttcatacttg cgtaaaacag ctgccaaggt ctctaactgc tctcgactgt aggtaattcc
    36661 tgtcggattg gctggatagt tgagaataac caccttgagc ttatcaccct gctccaaaat
    36721 ggccttctcc aacatctcag gagtcaagac aaaaccattt tcagtcgtat caatctcaac
    36781 aatttctgcc ccaactaagt taacaatcgg ttcatagcct ggataagcag gagctggcaa
    36841 aagtaccttg tctccctctt ccaaaatagc cgtcaaagtc gcagataaag cctctgtcgc
    36901 cccaattgta accaagattt cattttcagg agcatagtcc agttggtact tttccttaac
    36961 aaagtcacta gctgcctgac gtagagtcag cagaccactc atccctgtat agtaggattg
    37021 gttctgatca atcgctcgct tggccgcctc cttgacatgg tctggcgttg taaaatcagg
    37081 ttcccccaag gtcaaacgca agaccccagg aatctccgaa atagcctggt caaactgacg
    37141 aatcaacgaa acttgaattt tatctaactg tttattaaag cgcttagtta agtccataga
    37201 tacctcctac tttcaaaacg tatctctatt atactacaaa agcctcccga ccgcaaaaat
    37261 acattagaga atagctttcc actttctatt ttacttttcc tctttacagg tctataatgg
    37321 taacagattc tatttggagg tttttatgtc atttctatca aaaaatggag caggcatctt
    37381 ggtctgcctt ctcatttcta tcgtatcttg gtacttagga ggattcttcc ctgtgattgg
    37441 cgcacccgtt tttgcgattt ttatgggcat gctcctacat ccctttctct cgtcttataa
    37501 acaactggat gctggattga cctttagttc caagaaattg ctccagtatg ccgttatctt
    37561 gcttggtttt ggtctcaata tctctcaagt cttcgcagtt gggcaatctt cactccctgt
    37621 catcctttcc accatttcaa tagccttgat tgttgcctac ctcttccagc gcttctttgc
    37681 cctggataca aaactggcta ccttgattgg agtaggttct tctatctgtg ggggttctgc
    37741 cattgcagcg acagcgcctg ttatccatgc taaggaaaag gaagtagccc aagccatctc
    37801 cgttatcttt ttcttcaatg tcttggctgc gctcatcttt ccaaccctcg gcacctggct
    37861 tcatctatcc aatgacggct tcgccctctt tgcaggaact gcggtcaatg atacttcctc
    37921 tgtaaccgcc acagctagcg cttgggacag tctctaccag accaatgccc tcgaatccgc
    37981 aaccattgtc aaactcacgc gcaccctagc tatcatcccc atcactatct ttctctccta
    38041 ctggcaaagt cgcgagcaaa aaaataagca aggcttacaa ctgaaaaaag tcttcccact
    38101 ttttatcctt tacttcatcc ttgcatcgct cctaaccacc cttctgacct ctctcggtgt
    38161 gtctagtagt ttctttaccc ctctcaaaca actctctaaa ttcctcatta tcatggccat
    38221 gagtgccatc ggtctcaaaa ctaatctggt cgctatggtc aaatccagtg gaaaatccat
    38281 tgttctcgga gccgtctgct ggattgccat catcctcacc agccttggta tgcagaccct
    38341 tatcggcatt ttctaatact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc
    38401 gtatatatgt t
//
LOCUS       DAVBOH010000017        37851 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOH010000017 DAVBOH010000000
VERSION     DAVBOH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.017"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..369
                     /locus_tag="VQ873_000940"
     CDS             <1..369
                     /locus_tag="VQ873_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3107221.1"
                     /translation="SPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLES
                     KGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDYYNNK
                     RIKVKLKGLSPVQYRTKSFG"
     gene            complement(414..1055)
                     /gene="plsY"
                     /locus_tag="VQ873_000941"
     CDS             complement(414..1055)
                     /gene="plsY"
                     /locus_tag="VQ873_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3107222.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1191..3134
                     /gene="parE"
                     /locus_tag="VQ873_000942"
     CDS             1191..3134
                     /gene="parE"
                     /locus_tag="VQ873_000942"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3107223.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3554..6025
                     /gene="parC"
                     /locus_tag="VQ873_000943"
     CDS             3554..6025
                     /gene="parC"
                     /locus_tag="VQ873_000943"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3107224.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6157..7179
                     /locus_tag="VQ873_000944"
     CDS             6157..7179
                     /locus_tag="VQ873_000944"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3107225.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7235..7939
                     /locus_tag="VQ873_000945"
     CDS             7235..7939
                     /locus_tag="VQ873_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107226.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8004..8693
                     /locus_tag="VQ873_000946"
     CDS             8004..8693
                     /locus_tag="VQ873_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3107227.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8690..9613
                     /locus_tag="VQ873_000947"
     CDS             8690..9613
                     /locus_tag="VQ873_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3107228.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9628..10272
                     /gene="pcp"
                     /locus_tag="VQ873_000948"
     CDS             9628..10272
                     /gene="pcp"
                     /locus_tag="VQ873_000948"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3107229.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10440..10670
                     /locus_tag="VQ873_000949"
     CDS             10440..10670
                     /locus_tag="VQ873_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3107230.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10720..10800
                     /locus_tag="VQ873_000950"
     tRNA            10720..10800
                     /locus_tag="VQ873_000950"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10754..10756,aa:Tyr,seq:gta)
     gene            10810..10881
                     /locus_tag="VQ873_000951"
     tRNA            10810..10881
                     /locus_tag="VQ873_000951"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10842..10844,aa:Gln,seq:ttg)
     gene            11043..12245
                     /gene="rpsA"
                     /locus_tag="VQ873_000952"
     CDS             11043..12245
                     /gene="rpsA"
                     /locus_tag="VQ873_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3107231.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12331..12828
                     /locus_tag="VQ873_000953"
     CDS             12331..12828
                     /locus_tag="VQ873_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3107232.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12828..14483
                     /gene="dnaX"
                     /locus_tag="VQ873_000954"
     CDS             12828..14483
                     /gene="dnaX"
                     /locus_tag="VQ873_000954"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3107233.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14511..14705
                     /locus_tag="VQ873_000955"
     CDS             14511..14705
                     /locus_tag="VQ873_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3107234.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14855..15625
                     /gene="sufC"
                     /locus_tag="VQ873_000956"
     CDS             14855..15625
                     /gene="sufC"
                     /locus_tag="VQ873_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3107235.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15653..16915
                     /gene="sufD"
                     /locus_tag="VQ873_000957"
     CDS             15653..16915
                     /gene="sufD"
                     /locus_tag="VQ873_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3107236.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16926..18152
                     /locus_tag="VQ873_000958"
     CDS             16926..18152
                     /locus_tag="VQ873_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3107237.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18139..18579
                     /locus_tag="VQ873_000959"
     CDS             18139..18579
                     /locus_tag="VQ873_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3107238.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18633..20045
                     /gene="sufB"
                     /locus_tag="VQ873_000960"
     CDS             18633..20045
                     /gene="sufB"
                     /locus_tag="VQ873_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3107239.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20244..21485)
                     /locus_tag="VQ873_000961"
     CDS             complement(20244..21485)
                     /locus_tag="VQ873_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3107240.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21588..22697
                     /locus_tag="VQ873_000962"
     CDS             21588..22697
                     /locus_tag="VQ873_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3107241.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23343..23690
                     /gene="ssrA"
                     /locus_tag="VQ873_000963"
     tmRNA           23343..23690
                     /gene="ssrA"
                     /locus_tag="VQ873_000963"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23873..23960)
                     /locus_tag="VQ873_000964"
     tRNA            complement(23873..23960)
                     /locus_tag="VQ873_000964"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23924..23926),aa:Ser,seq:gga)
     gene            24122..24862
                     /locus_tag="VQ873_000965"
     CDS             24122..24862
                     /locus_tag="VQ873_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3107242.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24859..25770
                     /gene="pfkB"
                     /locus_tag="VQ873_000966"
     CDS             24859..25770
                     /gene="pfkB"
                     /locus_tag="VQ873_000966"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3107243.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25767..27719
                     /locus_tag="VQ873_000967"
     CDS             25767..27719
                     /locus_tag="VQ873_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107244.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27883..30108
                     /locus_tag="VQ873_000968"
     CDS             27883..30108
                     /locus_tag="VQ873_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3107245.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30261..30689)
                     /locus_tag="VQ873_000969"
     CDS             complement(30261..30689)
                     /locus_tag="VQ873_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107246.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30827..31969
                     /locus_tag="VQ873_000970"
     CDS             30827..31969
                     /locus_tag="VQ873_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3107247.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31978..33192
                     /gene="thiI"
                     /locus_tag="VQ873_000971"
     CDS             31978..33192
                     /gene="thiI"
                     /locus_tag="VQ873_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3107248.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33327..34151
                     /locus_tag="VQ873_000972"
     CDS             33327..34151
                     /locus_tag="VQ873_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3107249.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34164..35330
                     /locus_tag="VQ873_000973"
     CDS             34164..35330
                     /locus_tag="VQ873_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3107250.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35838..37331
                     /locus_tag="VQ873_000974"
     CDS             35838..37331
                     /locus_tag="VQ873_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3107251.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37344..>37851
                     /locus_tag="VQ873_000975"
     CDS             37344..>37851
                     /locus_tag="VQ873_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3107252.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11452 a         6882 c         8388 g        11129 t
ORIGIN      
        1 tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac
       61 gagaatacga ttctccatag tgaccaaggc tggcaatatc aacacgattc ttatcatcgg
      121 ttcttagaga gtaagggaat tcaagcatcc atgtcacgca agggaaacag ccaagacaat
      181 ggtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
      241 tcgtttcagt cgcttaagca attggaacaa gccattatag actatattga ttactacaac
      301 aacaagagaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc
      361 ttcggataaa ttaattgtct aacttttggg gggcagttca cagaactggc attttatttt
      421 ttaggatctt gatgggttag gttcaatccc caagggacca aattttcagt tttatttttg
      481 atacgagcta tattgtcctt atgacgaatg ataatcaaac tagcaagtgc taagataata
      541 gcgatgaaga gagagtcata gttactcagg ataaaaccaa aaagtggaaa gagcagaacc
      601 ccgataacag ccgcgatcga tgctgtgaca ctagacagtg aaatcatact gccaagatag
      661 agagctccaa agaagataat cgcaaggtag agacagaaga taggcgcaaa tccgaaaatt
      721 actccagcac tggttgcgac agccttacca cctttaaatc ctgcaaagat agggaaggta
      781 tggccgataa cagccaaaag tccaaagatg agaggagaaa cgccttgtag atgaaaaata
      841 atcggaagca gcgttgctag ggttcctttg aaaaagtcaa tcacaaaggt tgccatacca
      901 gctttcttac ctaaaatgcg gaaggtattg gtcgttccag tgttaccaga accatgctcg
      961 cgtagattga tttgaaagaa tacttgtcca atccagagac cagatggaat cgaacccagc
     1021 agataggcta ggattaataa aactattgta atcatactcc tattatatca tgaattggga
     1081 aagaaaagca gagaatctct gctaaaattg tcacatcgga gaaagaaaaa ttttgcaaaa
     1141 tccttggaaa acctgtagaa tagtaaagat gaacgaatag gaggttcctt gtgtcaaaaa
     1201 aggaaatcaa tattaacaat tataatgatg atgctattca ggtgctagaa gggttggatg
     1261 cggtccgaaa acgtccaggg atgtatattg gatcgaccga tggcgctggt cttcatcacc
     1321 tagtttggga aatcgttgat aatgcagtcg atgaagcctt gtctgggttt ggtgatcgta
     1381 tcgatgtaac catcaataaa gacggtagtc taacggttca agaccatgga cgtgggatgc
     1441 cgacaggtat gcacgctatg ggaattccaa ctgttgaggt tatctttacc attcttcatg
     1501 ccggagggaa attcggtcaa ggtggctata agacatcagg tggacttcac ggagtgggtt
     1561 cttccgttgt taacgccctt tctagctggt tagaagttga aattacccgt gatggcgcag
     1621 tttacaagca acgtttcgaa aatggtggaa aacctgtcac gactttgaag aaaatcggta
     1681 cagcacccaa gtctaaaaca ggcaccaaag ttacttttat gcctgacgcg actatatttt
     1741 ctacgacaga tttcaagtac aataccattt cagagcgcct taatgaatca gcctttctct
     1801 tgaaaaatgt gaccttgtct ttaacggaca agcgaacaga tgaagcgatt gagttccact
     1861 atgagaatgg agtacaagat tttgtttctt atctcaacga agataaggaa atcttgacgc
     1921 cagttcttta ctttgaaggg gaagacaatg gttttcaagt ggaagtagcc ctccagtaca
     1981 atgacggatt ctcagataac attctatcct ttgtcaataa cgttcgcacc aaggacggtg
     2041 gaacgcacga gacaggactc aagtctgcca ttaccaaggt catgaatgac tatgcacgta
     2101 aaacaggtct tctcaaggaa aaagataaaa accttgaagg ttcagactat cgtgagggac
     2161 tagcggccgt tctttctatc ttagttcctg aagaacactt gcagtttgaa ggacagacca
     2221 aggataaact aggaagcccc ctagctcgcc cagttgtgga tggaatagtg gctgataagt
     2281 tgaccttttt ccttatggaa aatggggaat tagcttctaa cctcatccgc aaggctatca
     2341 aggcccgtga tgctcgtgaa gcagcacgta aggcgcgtga tgagagccga aatgggaaga
     2401 aaaacaagaa agataagggc ttgttgtctg ggaaattgac cccagcccaa tctaagaatc
     2461 ctgctaagaa tgaactctat ctagttgagg gggactctgc cggtggttct gccaaacaag
     2521 gtcgtgaccg caagttccag gctattctac ctcttcgtgg taaggttatc aatacagcca
     2581 aggccaagat ggcggatatc ctcaaaaatg aagagatcaa taccatgatt tataccattg
     2641 gtgcgggtgt tggagcagac ttctctattg aagatgccaa ctatgataag atcattatca
     2701 tgaccgatgc ggataccgac ggtgcccata tccagacctt gctcttgaca tttttctacc
     2761 gttacatgcg tccgctagtc gaggcaggtc atgtctatat tgccctccca cctctttaca
     2821 agatgtccaa aggtaaagga aagaaagaag aagtggccta cgcttggacg gacggagaac
     2881 tagaagaact ccgtaaacag ttcggtaaag gcgctaccct ccaacgatac aaaggacttg
     2941 gtgagatgaa tgcggaccag ctctgggaaa caaccatgaa cccagaaaca cgtaccctca
     3001 tccgtgtcac aattgaagat ttagcgcgcg ccgaacgccg cgtcaatgtt ctcatgggag
     3061 ataaggtaga accacgccgt aaatggattg aagataatgt caagtttacg ctagaagaag
     3121 cgacagtgtt ttaatgaaag aaaataatat gttagtaaac tggaaattag agtcggatgt
     3181 gaatgactat gtgaaaaagc agtttgaaaa tcttggtttg aaaaaattgc aggattatta
     3241 atgaagaatc tgctatgagt gcttatctca aagaggcgct taagggagcg gctaagacac
     3301 aaactaagac taattttgga aaaccagatt ttcatattga aaaatacaaa caggatagtt
     3361 tggttactta tcgtaactga acacgggagg aattcccgta aaatatcttt tactgcataa
     3421 aaacctactc tacattcttt gaaaggagtt gaacacgccc tagatactgt gtgaaaaaga
     3481 taaattctct tgtgagtttg cttacttcaa gaattttcta ttttcacttg gtattttatg
     3541 ggctttgtat cttatgtcta acattcaaaa catgtccctg gaggacatca tgggagagcg
     3601 ctttggtcgc tactccaagt acattattca agaccgggct ttgccagata ttcgtgatgg
     3661 gttgaagccg gttcagcgcc gtattcttta ttctatgaat aaggatagca atacttttga
     3721 caagagctac cgtaagtcgg ccaagtcagt cgggaacatc atggggaatt tccacccaca
     3781 cggggattct tctatctatg atgccatggt tcgtatgtca cagaactgga aaaatcgtga
     3841 gattctagtt gaaatgcacg gtaataacgg ttctatggac ggagatcctc ctgcggctat
     3901 gcgttatact gaggcacgtt tgtctgaaat tgcaggttac cttcttcagg atatcgagaa
     3961 aaatacagtt ccttttgcat ggaactttga cgatacggag aaagaaccaa cggtcttgcc
     4021 agcagccttt ccaaacctct tggtcaatgg ttcgactggg atttcggctg gttatgccac
     4081 agacattcct ccccataatt tagctgaggt catagatgct gcagtttaca tgattgacca
     4141 cccaactgca aagattgata aactcatgga attcttgcct ggaccagact tccctacagg
     4201 ggctattatt cagggtcgtg atgaaatcaa gaaagcttat gagactggga aagggcgcgt
     4261 ggttgttcgt tccaagactg aaattgaaaa gctaaaaggt ggtaaggaac aaatcgttat
     4321 tactgagatt ccttatgaaa tcaataaggc caatctagtc aagaaaatcg atgatgttcg
     4381 tgttaataac aaggtagctg ggattgctga ggttcgtgat gagtctgacc gtgatggtct
     4441 tcgtatcgct atcgaactta agaaagacgc taatactgag cttgttctca actacttatt
     4501 taagtacacc gacctacaaa tcaactacaa ctttaatatg gtggcgattg acaatttcac
     4561 acctcgtcag gttgggattg ttccaatcct gtctagctac atcgctcacc gtcgagaagt
     4621 gattttggcg cgttcacgct ttgacaaaga aaaggctgag aaacgtctcc atatcgtcga
     4681 aggtttgatt cgtgtgattt cgattttgga tgaagtcatt gctcttatcc gtgcttctga
     4741 gaataaggcg gacgccaagg aaaacctcaa agttagctat gattttacgg aagaacaggc
     4801 tgaggctatc gtaactttgc aactgtaccg tttgaccaat accgatgtgg ttgtcttgca
     4861 ggaagaagaa gcagagcttc gtgagaagat tgctatgctg gcggctatta tcggtgatga
     4921 aaggactatg tacaatctca tgaagaaaga acttcgtgag gtcaagaaga aatttgcaac
     4981 tcctcgtttg agttctttag aagacactgc gaaagcaatt gagattgata cagctagtct
     5041 tatcgctgag gaagatacct acgtcagcgt gaccaaggca ggttacatca agcgtaccag
     5101 tccacgttcc tttgcggctt ccaccttgga agaaattggc aagcgtgatg atgaccgttt
     5161 gatttttgtt caatctgcca agacaaccca gcacctcttg atgttcacaa gtcttggaaa
     5221 tgtcatctac agaccaatcc atgagttggc agatattcgt tggaaggaca tcggagagca
     5281 tctgagccaa accatcacaa actttgaaac gaatgaagaa atcctttatg tggaagtact
     5341 ggatcagttt gacgatgcga caacctactt tgcagtgact cgccttggtc aaatcaaacg
     5401 ggtagagcga aaagaattca ctccatggcg gacctataga tctaagtctg tcaagtatgc
     5461 taagctcaaa gacgatacag atcagattgt agcagtggct ccgattaaac tagatgatgt
     5521 tgtcttggtt agtcaaaatg gttatgccct gcgtttcaat atcgaagagg ttccggttgt
     5581 cggtgctaag gcagcaggtg tcaaggctat gaatttgaaa gaagatgatg tcctccaatc
     5641 tggctttatc tgtaatactt cgtccttcta cctcttgacc cagcgtggaa gcttgaaacg
     5701 tgtttctatt gaggaaattc tagcaaccag ccgtgccaaa cgaggattac aagtcttgcg
     5761 tgagttgaaa aacaaaccgc atcgtgtctt cttggcagga gcagttgcag agcaaggatt
     5821 tgttggcgat ttcttcagta cggaagtgga tgtgaacgac caaactctgc ttgtccaatc
     5881 caataaagga acaatctatg aaagccgatt gcaagacttg aacttgtcag aacgcactag
     5941 caatggaagc ttcatttctg acacgatttc agatgaagaa gtttttgacg cttatcttca
     6001 ggaagtagtt actgaagata aataagtgaa atgaagaatc agttctaaga gctggttttt
     6061 attggagaaa ttttctgaaa attacaaaat atacttgcta ttttagaaaa atagtgtaga
     6121 atataagaaa taggttttta gaataaggag tggaatatga cagtaacgat tgattgggaa
     6181 aacctcggtt tttcctatat gaaattacct tatcgctatc ttgctcattt caaaaatgga
     6241 caatgggatc aaggagagct tacagaggat gcaactttgc atatttcaga gtcttctcca
     6301 agtcttcact atggacaaca agcatttgaa ggtttgaaag cttatcgtac taaggatggc
     6361 agtgttcaac tgttccgtcc tgatgaaaat gctaaacgtc tgcaacgtac atgtgaccgt
     6421 ctcttgatgc cacaagttcc gacagacatg tttgtagaag cttgtaaagc agttgtccgt
     6481 gcgaatgaag aatacgtacc accatacgga acaggtggaa ccttatatct tcgccctctt
     6541 ttgattggtg tcggagatat tatcggggta aaaccggcag aagagtacat tttcaccatc
     6601 tttgctatgc cagttggaaa ttactttaaa ggtggtttgg tcccaaccaa cttcttgatt
     6661 caggatgagt acgaccgtgc agcaccaaat ggtacaggtg cggctaaggt tggtggaaac
     6721 tatgctgcaa gtctcttacc aggaaaaatg gccaagtcac gtcatttctc agatgttatc
     6781 tatctggacc catcaactca tacaaagatt gaagaagtcg gatcagctaa cttctttgga
     6841 attacagctg ataatgaatt tgtaacacca ttgagtccat ctatcttgcc atctattacc
     6901 aagtattcct tgctttattt ggcagaacat cgcttgggat taactcctat tgagggtgat
     6961 gttccaattg ataatcttga ccgttttgta gaggcaggtg cctgtggtac agcagcggtt
     7021 atttctccaa ttggaggtat tcaacatggt gatgatttcc atgtattcta tagtgaaaca
     7081 gaagtaggtc ctgtgacgcg taaattatat aatgaattga cgggtattca gtttggcgat
     7141 attgaagcgc cagaaggttg gattgtaaaa gtagattaaa ataaaccaaa ggagattttt
     7201 tatgaaatag aaaaagtggc tcttaacagc aggagtggtc ctgagcacgt cagctatttt
     7261 agtggcttgt ggaaaaactg ataaagaagc agatgcaccg acaacatttt cttatgtcta
     7321 tgcagtagat ccagcatcat tgggctacag tatagcgact cgaacatcga ggacagacgt
     7381 tattggaaat gttattgatg gtttgatgga aaatgataaa tacggcaatg ttgctccttc
     7441 tcaaaaagac tatgatttga acggtacagg atgggctcca agctatcaag atccagcgtc
     7501 ttacttgaat attatggatc caaaatctgg ttctgccatg aaacaccttg gcattacgaa
     7561 aggaaaagat aaggatgttg tagctaaacc tggtttggat aaatataaga aattgttaga
     7621 agatgctgtt tctgagacca ctgacctaga gaagagatat gaaaaatatg ccaaagctca
     7681 agcttggtcg acagatagtt cattattgat gccaacagct tcatctggtg gttttccagt
     7741 tgtaagtaac gtagtaccat tctcaaaacc atactcacaa gttggtatta agggggaacc
     7801 atatatcttt aaaggaatga aattgcaaaa agatattgtt acaacaaaag aatataacga
     7861 ggtttttaaa aaatggcaaa aagaaaaatt ggaatccaat agcaaatacc aaaaagaact
     7921 agaaaaatac attaaataag gaatggtatt gatcttgata aaatttttaa aatactgtca
     7981 ttttgaatat aaaggagttt gatatggagt ggattagatt aataggaata gcaatcattg
     8041 ttgtgggttt tattttaaaa tttgatacaa ttgcaacagt agtcttagct ggtttggtta
     8101 cagctttagt ttcaggtgtt tctctcgttg aatttttgga gattttggga aaagaattta
     8161 gcaatcagcg agtgctcacg atttttatgg ttaccttgcc tcttgtgggg ctgtcagaaa
     8221 cctttggact caagcaacga tcaatcgatt tgattcgaaa gattaaaggt ctgacagttg
     8281 gaaacttcta tacagtttat ttctttattc gagagttagc tggtttcttt tcaattcgtc
     8341 taggaggaca ccctcagttt gtcagacctt tggttcaacc tatgggagaa gcagctgcag
     8401 agtctcaatt aggtagaaag ttaacagagg ttgaagatga gacaataaaa gcgcgtgcgg
     8461 ctgcgaatga aaattttgga aatttctttg ctcaaaatac gtttgtaggt gctgggggag
     8521 tcctcttgat agggggaaca ttagatcagt taggctatga aagcaattat gcagggattg
     8581 cttctacatc tattattgtt gctgttataa cacttattgt agtggggatt tacaattatt
     8641 tatttgataa aaaattgata tcaaaaaaga ctaggggagg agaacaaaaa tgacagagtt
     8701 ggcaaagcaa ctattagagt tgacctatat tgtgattggt tgtcaatttc tccatacagc
     8761 ctattgtagt tataaagata aaacaaaccc agttcgactt gggacatctg cattttggac
     8821 tctattgtct attacgttta taggtggttc ctatatgcca aatatgagta ttggtattat
     8881 tgtaatccta ttatcgctgt taacattgtt taagcaagtc cgtatcggaa ccttgccatc
     8941 cttagatgaa atgaaagcca atattgaatc taacaggttg aaaaataaaa tttttattcc
     9001 agttatgctg atggcaatac ttgcgttggt cttagcgcaa atgattccag aatttagcaa
     9061 gatttcgatt agccttgccg ccttgtttgc tacaatttct gttcttgtga ttaccaatag
     9121 tcaccctaag agtctgttat cagaaaataa tcgaatgact cagcaagttt caacaagtgg
     9181 tattgttcct caattattag gggctttggg ggctattttt actgtagcag gtgttggtga
     9241 tgttatctct catctgatta gcggtattgt tccttcagat agtcgcttta taggagtttt
     9301 ggcttatgtt cttggaatgg ttctattcac aatgattatg ggaaatgctt ttgcagcatt
     9361 caccgttatt acagcaggtg ttggagttcc ctttgtattt gctctgggag ctaatccaat
     9421 tgtggctggt gctcttgcca tgacagcagg ttattgtggg accttattga ccccaatggc
     9481 tgctaatttt aacgctctac cagcagcatt gatggatatg aaagatcaga atggcgttat
     9541 aaaggctcaa gcaggtgttg ctctagtaat gattgttatt cacatattct taatgtactt
     9601 tctcgcattt tagtaaagga aaataaaatg aaaatattgg ttacaggttt taatcctttt
     9661 ggaggtgaaa agattaatcc agctttggag gctgtaaaat tattaccatc tgagattaat
     9721 ggggctgaag ttcgctgggt agaaattcca acggtttttt ataagtcgtc agaagtttta
     9781 gaggcagaaa tattacgata tcaaccagat gctgtacttt gtattggaca agcaggcggc
     9841 aggaccggct taacacctga acgagtggct attaatcaag atgatgctcg catacctgat
     9901 aacgaaggca atcaaccaat tgatacaccg attcgtattg atggagcatc ggcctatttt
     9961 agtagtttac ctatcaaagc gatggtacaa gctatcaaaa aacagggact tccggcagtt
    10021 gtatccaata gtgcaggaac ctttgtttgc aatcatttga tgtaccaagc tctttattta
    10081 gtggataaaa aattccctaa tatgagagca ggtttcatgc atattccata tatgatggaa
    10141 caagtagtaa ataagccgaa tactgcagga atgagtctat gtgatattgt aagaggcata
    10201 gaggtagcta ttgaagctat tgtagactac aaagataagg atttgcagtt agtaggcggt
    10261 gagactcact gataacctaa aaaggatagt caattatgct tgtttactaa ctattaacta
    10321 tgctaaatca attgaggttg tttacataaa actctatatc agagaagcct gatatagagt
    10381 tttttcttgc tagttttagg attttcttgt aaaatagaaa aagtgaagag aggtatgaaa
    10441 tgagcaagaa agataaaaaa atcgaaattc aagtagcgga tgccaaagtt aatgttggta
    10501 aagacagttt tgaaggttat acattgacta tcggtaaaaa agttatcgga gaaattgccg
    10561 aattagacgg acaatttgcc attataaaga atgggaatgt cgatagtttt tataaaaaat
    10621 tggaaaaagc tgtggaaatt ttgattgaaa attataattt agcaaaataa gtcttgtttt
    10681 tttgaaattt tcatgatata atagtccatg ttgattgtag gagagatagc gaagaggcta
    10741 aacgcggcgg actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tctctctcca
    10801 tttcattaat ggggtatagc caagcggtaa ggcaagggac tttgactccc tcatgcgttg
    10861 gttcgaatcc agctacccca gttcttaggt aataatcaag ataaaaagca aaatatctta
    10921 gggtatttta tttttataat tgaaagacgt gaatgatatg aacatgtcct tgcgggtgct
    10981 taggaaaaaa attataagta tgtcaagttt aagaaaaact tgattgttgg aggatttttt
    11041 agatgaacga atttgaagat ttgctaaata gcgttagtca agttgagact ggtgatgttg
    11101 ttagtgctga agtattgaca gttgatgcga ctcaagctaa cgttgcaatc tctggaactg
    11161 gtgttgaagg tgtcttgact cttcgcgaat tgacaaacga tcgtgatgca gatatcaatg
    11221 actttgttaa agtaggagaa gtattggatg ttcttgtact tcgtcaagta gttggtaaag
    11281 atactgatac agttacatac cttgtatcta aaaaacgcct tgaagctcgc aaagcatggg
    11341 acaaacttgt tggtcgcgaa gaagaagttg ttactgttaa aggaacgcgt gccgttaaag
    11401 gtggactttc agtagaattt gaaggtgttc gtggatttat cccagcttca atgttggata
    11461 ctcgtttcgt acgtaacgct gagcgttttg taggtcaaga atttgatact aaaatcaaag
    11521 aagttaacgc taaagaaaac cgcttcatcc tttcacgtcg tgaagttgtt gaagcagcta
    11581 ctgcagcagc tcgcgctgaa gtattcggta aattggctgt tggtgatgtt gtaactggta
    11641 aagttgctcg tatcacaagc ttcggcgctt tcatcgacct tggtggtgtt gacggattgg
    11701 ttcacttgac tgaattgtca catgaacgta acgtatcacc aaaatcagtt gtaactgttg
    11761 gtgaagaaat tgaagtgaaa atccttgatc ttaacgaaga agaaggacgt gtatcacttt
    11821 cacttaaagc aacagtacca ggaccatggg atggcgttga gcaaaaattg gctaaaggtg
    11881 atgtagtaga aggaacagtt aaacgtttga ctgacttcgg tgcatttgtt gaagtattgc
    11941 caggtatcga tggacttgtt cacgtatcac aaatttcaca caagcggatt gaaaatccaa
    12001 aagaagctct taaagttggt caagaagttc aagttaaagt tcttgaagtt aacgcagatg
    12061 cagaacgcgt gtcactttct attaaagctc ttgaagaacg tccagcccaa gaagaaggac
    12121 aaaaagaaga aaaacgtgct gctcgtccac gtcgtccaag acgtcaagaa aagcgtgatt
    12181 tcgaacttcc agaaacacaa acaggatttt caatggctga tttgtttggt gatatcgaac
    12241 tttaatcaaa ttgaaaattc acaaaatcct ttgtttacta aacaagggat ttttcttttg
    12301 tctctgctcc ttttttgata taatagttct atgttaaaat cagaaaaaca atcacgttat
    12361 caaatgttaa atgaagaatt gtccttccta ttggaaggcg aaaccaatgt tttggctaat
    12421 ctttccaacg ccagtgctct tataaaatca cgttttccta ataccgtatt tgcaggcttt
    12481 tatttgttcg atggaaagga attggtttta ggtcccttcc aaggaggtgt ttcctgcatc
    12541 cgtattgcac taggcaaggg tgtttgtggt gaggcagctc actttcagga aactgttatt
    12601 gttggagatg tgacgaccta tctcaactat atttcttgtg atagtctagc taaaagtgaa
    12661 attgtggtgc cgatgatgaa gaatggtcag ttacttggag ttctggatct ggattcttca
    12721 gagattgagg attacgatgc tatggatcga gattatttgg aacaatttgt cgctattttg
    12781 cttgaaaaga caacatggga ctttacgatg tttgaggaaa aatcttaatg tatcaagcac
    12841 tttatcgaaa atatagaagt caaaacttct cccagttagt tggtcaagaa gttgtggcta
    12901 agactcttaa acaagcggtg gagcaagaga aaataagtca cgcttatctt ttttctggtc
    12961 ctcgtggaac gggaaaaacc agtgttgcta aaatctttgc caaggctatg aactgtccca
    13021 atcaagtggg tggcgaacct tgcaataact gctatatttg tcaagcagtg acggacggta
    13081 gtttagaaga tgtcattgaa atggatgcag cttctaataa tggggtagat gaaattcgcg
    13141 aaattcgtga taaatctacc tatgcgccta gccttgctcg ttataaggtt tatatcatag
    13201 atgaggttca catgctgtct acaggggctt ttaatgccct cctaaagacg ctggaagaac
    13261 caacacagaa tgtagtcttt attttggcca ctactgaatt gcacaagatt cctgctacta
    13321 ttctatcccg tgtgcaacgt tttgagttta aatcaattaa gacacaggat attaaggaac
    13381 atattcacta tatcttagaa aaagaaaata tcagttctga accagaggct gtggaaatca
    13441 ttgccagacg ggcggaaggt ggaatgcggg acgccttgtc tattttggat caagccctga
    13501 gtttgacaca gggaaatgag ctgacgactg ctatctctga agaaattact ggcaccatta
    13561 gcctatcagc cttggatgat tatgtggcgg ccttgtctca acaggatgtt cccaaagctt
    13621 tgtcttgctt gaatcttctt tttgacaatg gtaagagcat gactcgtttt gtgaccgatc
    13681 ttttgcacta tttaagagac ttgttaattg ttcaaacagg gggagaaaat actcatcata
    13741 gttcagtctt tgtagaaaat ttggcacttc ctcaaaaaaa tctgtttgaa atgattcgct
    13801 tagcaacagt gaatttagca gatattaagt ctagtttgca gcccaagatt tatgctgaaa
    13861 tgatgaccgt ccgtttggcg gaaatcaagc ccgaaccagc tctatcagga gcggttgaaa
    13921 atgaaattgc tacgctgaga caggaagttg cccgtctcaa acaagagctt tctaatgcag
    13981 gtgcggttcc taaacaagtt gcaccagctc ctagtcgacc agctacgggc aaaacagtct
    14041 atcgtgtcga tcgcaataaa gtgcaatcta tcttacaaga ggccgtcgaa aatcctgatt
    14101 tagcacgtca aaatctaatt cgtttgcaga atgcctgggg agaggtaatt gaaagtctag
    14161 gtgggccgga caaggctctg ctagttggtt ctcaaccggt tgctgccaat gaacaccatg
    14221 ctattcttgc ttttgagtct aacttcaatg ctggtcaaac tatgaaacga gacaatctca
    14281 ataccatgtt tggtaatatc ctcagtcagg cggcaggttt ttcacctgag attttagcta
    14341 tttccatgga ggaatggaaa gaagttcgcg cagccttttc agccaaagcc aaatcttctc
    14401 aaactgaaaa agaagtagaa gaaagcctga ttccagaagg atttgaattt ttggctgata
    14461 aagtgaaggt agaggaagac taaagaaaga tttcatgata caataagttt atgaataaac
    14521 aacaatttat tattatggcg ctatttacag ctgctgagac ctattttttc aatgaagcct
    14581 ggatgactgg ccgctatatt atggcagcct tttgggcaat tttactcttt agaaatttcc
    14641 gagtcagtta tgtgatgggt aaaattgttg atgtcatcga tcagcatttt aataggaaag
    14701 actagccctc agcttccaga caaaatcaaa gccttttagg cttttttttg ttatactaga
    14761 aaagtatatt tatagaattt ttgctctatt tctggggaaa tcagacgttt ttctagtaag
    14821 tactgtaaaa gttttgaaaa agaaaggaac tatcatgtca gtaatagaga tcaaagatct
    14881 tcacgttgag attgaaggaa aagaaatttt aaaaggggtt aacctgaccc tgaaaacagg
    14941 agaaattgcc gctatcatgg gaccaaatgg tacaggtaaa tcgactcttt ctgccgctat
    15001 catgggaaat ccaaactatg aagtaactaa aggtgaagtt ttgtttgatg gcgtaaacat
    15061 ccttgagttg gaagtggatg agcgtgcgcg tatgggactt ttccttgcta tgcaataccc
    15121 atcagaaatc cctggaatta ccaatgctga gtttcttcgt gccgctatga atgcgggtaa
    15181 agaagatgat gagaagattt cagttcgtga gtttattact aagctagatg aaaaaatgga
    15241 attgctcaac atgaaagaag aaatggcaga gcgttacctc aacgaaggct tctctggtgg
    15301 tgagaaaaaa cgcaatgaaa ttcttcaact tttgatgttg gagccaacat ttgctctttt
    15361 ggacgagatt gactcaggtc ttgatattga cgctcttaaa gttgtgtcta aaggtgtcaa
    15421 tgccatgcgt ggtgaaggtt ttggtgctat gatcatcact cactaccaac gtcttttgaa
    15481 ctatatcaca cctgatgtgg tacacgtgat gatggaaggt cgtgttgtcc tttctggtgg
    15541 tccagaattg gctgcgcgtt tggaacgtga aggatacgca aaattagctg aagaacttgg
    15601 ctacgactac aaggaagaat tgtaatttcc tcgtatcttt taggagaagt aaatgactag
    15661 agaaaatatt aaactttttt cagaaatgca cgctgaacca agctggttgg ctgatctccg
    15721 tcaaaaagct tttgacaaga ttgagacttt ggaattacca gttattgagc gtgtcaaatt
    15781 ccaccgttgg aatctgggtg atggaacgat tacagaaaat gagccatcag caaatgttcc
    15841 agatttcaca gctttagatc atcacttgaa gttggtgcaa gtaggaactc aaactgtttt
    15901 cgaacaaact ccagttgagt tagctgaaca gggtgttgtc ttcacagact ttcactcagc
    15961 tttagaagaa attccagagc tgatcgaaga attcttcatg tcatctgtta agtatgatga
    16021 tgacaagttg gcggcttacc acacagctta ctttaacagt ggtgctgtac tctatattcc
    16081 agataacgta gaaatcacag agccaattga aggaattttc taccaagata gcgatagcaa
    16141 tgtgccgttt aacaagcata ttatgattat cgctggtaaa aattctaaga ttagttatct
    16201 ggagcgttta gagtcacgcg gtgaaggaag tgacaaagca actgccaata tcacagtgga
    16261 agtgattgca cattctggtg cgcaagtcaa gtttgctgct atcgaccgtc taggtgaaaa
    16321 cgtcactgcc tacattagcc gtcgtggtaa attaggcaac gatgcaagta ttgactgggc
    16381 tatcggtgtc atgaacgaag gaaatgtcgt tgctgatttt gatagtgact tgattggtaa
    16441 tggtagctat gctgacctca aggttgtagc tctttcaagt ggtcgtcagg tacaagggat
    16501 tgatactcgt gtaactaact atggctgcaa ctctatcgga aatatcctac aacatggggt
    16561 tatccttgaa aaagcaactt tgactttcaa tggtatcggc cacatcatca agggtgctaa
    16621 gggagcagat gcccaacaag agagccgtgt tctcatgctt tcagaccaag cgcgttcaga
    16681 tgctaaccca attcttttga ttgatgaaaa tgatgtcact gcaggacacg cagcgtctat
    16741 cggacaagtt gatccagaag acatgtatta cctcatgagt cgtggattgg ataaggcaac
    16801 tgcagagcgt ttggttgttc gtggtttcct tggatctgtt atcgtggaga ttccagtcaa
    16861 ggaagttcgt gatgaaatga ttgcaactat cgaagagaaa ttgtcaaaac gctaagggga
    16921 agcctatgtt agatgtagaa gcgattcgca aggattttcc aattttagat cagattgtca
    16981 atgatgaacc tctggtctat ctggacaatg ctgcgacgac acaaaaacca ctagtagttc
    17041 tgaaagctat taacagttac tatgagcagg acaatgccaa tgttcaccgt ggtgtccata
    17101 ccttagcgga acgagcgaca gcttcttatg aagctgctcg tgaaaccatt cgtaagttta
    17161 ttaatgcagg ctctacaaag gaagttctct ttaccagagg aacgacaacc agccttaact
    17221 gggtggcacg ctttgctgag gaaattctca ctgagggaga ccaggtcttg atttcagtaa
    17281 tggaacacca ttctaatatc attccatggc aggaagcttg tcgaaagact ggagcagagc
    17341 ttgtctatgt ctatcttaaa gacggtgcct tggatatgga ggatttgcga gctaaattga
    17401 ctgataaggt taaatttgtt tccctagctc atgcctccaa tgttcttggt gtggtcaatc
    17461 cgatcaagga aatcactcaa ttagcccacc aagttggggc aatcatggta gtggatggtg
    17521 ctcaatctac acctcatatg aagattgatg tccaggactt ggatctggac tttttcgcct
    17581 tttcgggtca caagatggct ggtccgactg gtatcggtgt cctttacggc aaagaaaagt
    17641 atcttgagca aatgtctcca gtagaatttg gcggcgagat gattgatttt gtctacgagc
    17701 aatccgctag ttggaaggaa ttgccttgga aatttgaggc tggaacgcca aatatggcag
    17761 gagctattgg acttgcgact gcagttgatt atctggaaaa gattggtatg gatgccgttg
    17821 aagctcatga acaggaattg attgcgtacg tctatccaaa actgcaggca attgagggat
    17881 tgaccattta cggttctcag gatttggctc aacgttcggg tgttattgcc tttaacctag
    17941 gtgatctcca tcctcacgat cttgcgacgg ctctggatta tgaaggagtg gctgttcgtg
    18001 ctggtcacca ttgtgcgcaa cccttgcttc agtatttgga agtctcagca acagctcgtg
    18061 caagttttta tatctataat accaaggcag attgcgacaa actagtcgat gccctacaaa
    18121 agacaaagga gtttttcaat ggcactttct aaactagata gcctttatat ggcagtggta
    18181 gcagaccatt cgaaaaatcc acatcaccaa gggaagttag aagacgctga gcaaatcagt
    18241 ctcaacaatc cgacttgtgg agatgtcatc aatctctctg tcaagtttga tgcagaggac
    18301 cgtttggaag atattgcttt tctaaattca ggatgcacga tttcaactgc ttctgctagt
    18361 atgatgacag atgccgtttt aggaaaaacc aaacaagaaa ttttagaact ggcgactatt
    18421 ttttctgaaa tggttcaagg gcaaaaagat gagcgtcaag accaacttgg agacgcggca
    18481 ttcttgtcag gtgttgccaa attccctcaa agaatcaagt gtgcaaccct agcttggaat
    18541 gcccttaaga aaacaattga aaatcaagaa aaacagtaag acaagtttct tttgtcttat
    18601 gaattattag aaatgaagaa agaaaggata ttatggctga agaaagagta gaaccaaaac
    18661 caattgacct tggtgaatat aaatttggtt tccatgacga tgtagagcct gtcttatcga
    18721 caggaaaagg actcaacgaa ggtgttattc gtgaattatc tgctgctaag ggtgagcctg
    18781 agtggatgtt ggagttccgt ttgaagtctt atgaaacctt caaaaaaatg cccatgcaaa
    18841 cttggggagc agacttgtca gagattgact ttgatgactt aatctactac caaaaaccat
    18901 ctgacaaacc agcccgttct tgggatgatg tacctgaaaa gattaaagaa acctttgaac
    18961 gtatcgggat tccagaagct gaacgtgctt atttagcagg ggcttctgcc cagtacgagt
    19021 cagaagtggt ttaccacaac atgaaggaag agttccaaaa attaggtatt atctttacag
    19081 atacagattc cgcactcaag gaatacccag acttatttaa tcaatacttt gcgaagttgg
    19141 taccgccgac agataacaag ttggcagccc tcaactcagc agtatggtcg ggtggaactt
    19201 ttatctacgt gccaaaaggt gtcaaggtag atattccact tcaaacttat ttccgtatca
    19261 ataacgaaaa tataggtcag ttcgaacgta ccttgattat cgttgatgag ggagcaagcg
    19321 tccactacgt agaaggatgt acagcaccaa catattcaag caatagctta cacgctgcca
    19381 ttgtagaaat ttttgctttg gacggagctt atatgcgtta tacaactatc caaaactggt
    19441 ctgataacgt ctataacttg gtaacaaagc gtgctaaggc tcaaaaggat gccactgttg
    19501 agtggattga tggaaacttg ggtgccaaaa cgactatgaa atatccatct gtttaccttg
    19561 atggagaagg agcgcgtggt accatgctct ctatcgcctt tgctaatgca gggcaacacc
    19621 aagacacggg tgctaagatg attcacaatg ctccacatac cagctcgtct attgtgtcta
    19681 aatccatcgc taaaggtgga ggaaaggttg actaccgtgg acaagtcacc tttaacaaga
    19741 actctaagaa atctgtttcc cacattgaat gtgataccat tatcatggat gacttgtcag
    19801 catcagatac tattccattt aatgaaattc acaactcgca agtggctttg gaacacgaag
    19861 ccaaagtatc taagatttca gaagagcaat tgtattatct catgagccgt ggattgtcag
    19921 aatctgaggc aactgaaatg attgtcatgg gatttgtaga accctttaca aaagaacttc
    19981 caatggaata cgcagttgag ctgaaccgct tgattagcta tgaaatggag ggatcagttg
    20041 gataaaattt gattttatac tcttcgaaaa tctcttcaaa ccacgtcagc atcgccttat
    20101 cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc
    20161 aacctgcggc tagcttccta gtttgttctt tgattttgaa gatgaacttg tatcaaaaaa
    20221 tcgcggttta aaatcgcgat tttttataat ttctcgttaa caaagcggac aaactgattc
    20281 caccaaactt ttaagaagaa ggctttttca attttcttgt ctgctaccat ttcgaaacta
    20341 gggcgctctg tggtgatgta accttgacca atcaagtcct tgtcttcata agtcaaatgg
    20401 ccaaccactg ttccagcttc aagtggtgct gggattgctt tggaatcagg tgtgaattga
    20461 acagattgag aagattgatt cccaacacgt tcgattagat agatatcctc tggagccact
    20521 gcagttactg tatcttcttt tccatcttgt acaggggctt tgctatcttg ataggcatcg
    20581 ccttgttgaa cgattttgcg aagtgtaaat gtagaagaaa tataatccat tagggaagat
    20641 gtagctgtaa atcgagcgta aggattattg tcttgatgat ctgcatttaa aacaactgtg
    20701 atgactctca tgcctttttc gacagtagta ccaacaaaag actctccagc cttatctgtt
    20761 gttcctgttt ttagcccatc aaaaccacca cggtaagcag gcataccttc taacatgtag
    20821 ttggttgaag tgattgtcat cccagcaaaa gtagaagaag gttttttggt gatttctaag
    20881 acttgtgggt attttttgat gaggttgcga gcaacgatag cgacatcata agcactaagc
    20941 ttattttcct catctttttt agaacctggg taaatgttat cccctagagt ttcattgtta
    21001 agacctgtcg tattgacaac agtggcatcc tgaattcccc attccaagag ttttgcccgc
    21061 atcatatcga cgaaatcttt ttctgagcca gcaattttct cagctagggc aatagcggcg
    21121 ctgttggcac tagataccag agttgcttca agcaactctt cgacagtata attacgggcc
    21181 tccataggaa tattactggc ttcagaattt gtcgtcaatt gataaggata atcagaaata
    21241 tctacaggag tggagagggt aatacttccg ttttccaaag cttcatagac tagataaaca
    21301 gtaatcaatt ttgttatgga agcaatttcg acaggttgcg ttgcatcctt ctcatagaga
    21361 attttaccag tatttgcctc aacagcaatc gcatgtttag cggcaatggt aaaatcttga
    21421 gcaacagcag tagaaacacc ccctaaaaga gagacagtta acaaagttaa aaatattttt
    21481 ttcatagtag tcttattcta tcataaagaa aaaaaatatt cttgctttaa taattcatct
    21541 gttaagcttt ttgaaaatat ggtaaaataa agtgagggag gtaactcatg tttcgtagaa
    21601 ataaattatt tttttggacc acagaaattt tactcttaac catcatcttt tacctatgga
    21661 gacagatggg atctttgatt aacccttttg ttagcgtgct taatacaatt atgattccat
    21721 ttttattagg gggctttctt tattatttga caaaccctat tgttactttc ttaaataaag
    21781 tctgtaaact caatcgtttg cttggtattt taattacctt gtgtactttg gtctggggaa
    21841 tggtcatagg tgttgtctat ctcttaccta ttttgattaa tcagttatct agtttgatta
    21901 tatctagtca aactatttat agtcgagtac aagacttaat catagactta tctaattatc
    21961 ctgcgctcca gaatttggat gtagaagcta caattcagca gttaaactta tcctatgttg
    22021 atattcttca aaatatccta aatagcgtat caaatagtgt ggggagcgtc ttgtcagctc
    22081 ttatcagtac tgttttgatt ttgattatga ctccagtttt tttggtttat ttcttattag
    22141 atggacataa attcttgccc atgcttgaaa gaacgattct aaagagggat cgcttgcata
    22201 ttgcaggctt attaaagaat ttaaatgcga cgattgctcg ctatattagt ggagtttcga
    22261 ttgacgcaat cattataggt tgtttggctt atattggcta tagtattatt ggtttaaaat
    22321 atgctttagt ttttgccatt ttttctggtg tagccaattt aattccttat gtggggccaa
    22381 gtattggttt gattcctatg atcatcgcaa atatattcac tgatccccat agactgctga
    22441 ttgcagtgat ttatatgctt gttgttcagc aggtagatgg caatatctta tatcctcgaa
    22501 ttgtaggaag tgttatgaag gttcatccaa tcacgatttt agttttactt ttgttgtcaa
    22561 gcaatatcta tggtgtagtt ggaatgattg tcgcagtgcc aacctattct atcttgaaag
    22621 aaatttctaa gttcttatcc cgtttgtatg aaaatcataa aataatgaaa gaacgagaaa
    22681 gagaattagc taagtaaaag tcaggagaac cctgattttt ctttactgga agtggccttt
    22741 agattagaag actgaaaata agttaaagtc ttaaactaat tttcacagct aagaatagta
    22801 gaagttaatc tgataaaaat cgaaaaaacc agtggaattc cgtgtcaggg taagttccac
    22861 tggttttcat agtctattaa agttcgaatg aaacctattt atagtatatt gaaactagaa
    22921 tagtacacct ctaattctaa aacattgtta gaaatcgatt tgactgtcct gatctattcg
    22981 tcctattctt atttcatttt actatatttt ggtgcaataa gtgaaaagta gtccgaataa
    23041 tataaggatt gattttatag tttttaaact caaatgaatt aaaataaaga gagtacgaaa
    23101 attctcatct gaaagtattt tagaataatt ctcttcgtga atttcttcaa aacagatagc
    23161 ttcatcttag gtatgtgtta attggatttc gtaagctcta tttacaatcg taaagttatg
    23221 cactgaaaaa gttgtagtta gtcttccagt ttgctaaatt tctcgaatag tatctttttt
    23281 aggtatgtga tttctttttg catttttgag ttagataagg tataatggtt ttattgtctt
    23341 ttggggtcgt tacggattcg acaggcatta tgaggcatat tttgcgactc gtgtggcgac
    23401 gtaaacgctc agttaaatat aactgcaaaa aataacactt cttacgctct agctgcctaa
    23461 aaaccagcag gcgtgacccg atttggattg ctcgtgttca atgacaggtc ttattattag
    23521 cgagatacga ttaagccttg tctagcggct tgataagaga ttgatagact cgcagtttct
    23581 agacttgagt tatgtgtcga ggggctgtta aaataataca taacctatgg ttgtagacaa
    23641 atatgttggc aggtgtttgg acgtgggttc gactcccacc ggctccatta ttcctttgca
    23701 ttcttttgca ttccttggta aaacgttgtt aaatcaacgt tttttatttt tatctttggt
    23761 attcctttgc attcttttgc taaaaaggga gtcacaaaca gaccctattt taaaaaaagg
    23821 atagaaaaaa ggatacaaca tttgtcgcat cctaaaaata atcttttttc gacggaagac
    23881 atgggattcg aacccacgca cgctattaca cgcctaccgc gtttccaaca cggcctctta
    23941 agcctcttga gtaatcttcc aatacttact caaatagtct accataaagg ctcttatctt
    24001 gcaataaaaa ttctagaaat aagaaaaatg atagattttg aaagaaaatg ataaaaaatg
    24061 cttgacttca aaagaaagta tgatagaatg aatagtgtaa acgataacag gaggtgattc
    24121 ggtgttaaaa acagagcgga agcaactgat tttagaggag ttaaatcaac atcatgtagt
    24181 ttctctagaa aaattagtta gtttgctaga aacgtcagaa tcaacggttc gaagagactt
    24241 ggatgagttg gaagcggaaa acaagcttcg tcgtgtgcat ggtggagcag aactccccca
    24301 ctccttacag gaagaagaaa ccattcaaga aaaatcggtc aaaaaccttc aagaaaagaa
    24361 gttgctggct cagaaagcag cctctctcat taaagaaaaa gatgtcatct ttatcgatgc
    24421 tggaacaaca actgcttttt tgattcatga attggtcaat aagaatgtta cagttgtgac
    24481 caactccatt caccatgccg ctcagttggt tgaaaagcag attccaactg tcatggttgg
    24541 aggaaacgtc aagacggcga cagatgctag tatcgggggc gttgctctta accagattaa
    24601 ccaattgcac tttgaccgtg cctttatcgg aatgaatggt gttgacgatg gctattatac
    24661 gactcctgat atggaggagg gagctgtgaa aagagctatt ttggagaatg ccaagcagac
    24721 ctacgtcttg gtggattcgt caaaaattgg acaaacttgc tttgccaagg tagcaccact
    24781 caaacgcgct atcgttatca ctagtcaagg gcatgagctc ttgcaggtta ttaaggagaa
    24841 aacggaggta atagaagtat gatttataca gtcacactca atccatccat tgactatatc
    24901 gttcgtttgg accaagtcaa agttggtagt gtaaatcgta tggacagtga tgataagttt
    24961 gctggtggga aaggaatcaa tgtcagccgt gtcttgaaac gtttgaatat accaaataca
    25021 gcgacgggat ttatcggtgg ctttactggt aaatttatca cagatacttt agcagaggaa
    25081 gaaatcgaga cacgttttgt ccaggtggca gaagatactc gtatcaatgt taaaatcaaa
    25141 gcagaccaag aaacagaaat caacggaacg ggtccaactg ttgaaccggt tcagctagaa
    25201 gaattgaaag ctattttatc tagtctgaca gcagaagata cagttgtctt tgcaggttca
    25261 agtgctaaaa atctaggcaa tgttatctat aaggatttga tttccttgac gcgccagact
    25321 ggtgcgcaag tggtctgtga ctttgaagga cagaccttaa ttgatagttt ggactaccag
    25381 cctcttcttg taaaaccaaa caatcatgaa cttggagcga tttttggggt taaactcgaa
    25441 agtttagatg aaattgagaa atacgctcgt gagttactgg ctaagggtgc tcaaaatgtt
    25501 attatctcta tggctggtga tggcgccctt cttgtcacat ctgagggagc ttacttcgct
    25561 aaaccaatca aaggaacagt caaaaattca gttggagctg gtgattctat ggttgctgga
    25621 ttcacaggtg aatttgtcaa atcaaaagac gcagtagaag ccttcaaatg gggagtggct
    25681 tgcggaacgg caactacctt ctcagatgac ttggcaacgg cggaatttat taaagaaaca
    25741 tatggaaaag ttgaggtaga aaaaagatga aaattcaaga cctattgaga aaagatgtca
    25801 tgttgctaga tttgcaggca actgaaaaaa cagctgtcat cgacgagatg attaaaaatt
    25861 tgacagagca cggttatgta acagattttg aaacatttaa agaaggaatt ttggcgcgtg
    25921 aagctttgac ttctactggt ttgggtgatg gaatcgcaat gcctcacagc aaaaacgctg
    25981 ctgtcaaaga agcgacagtt ctatttgcta agtcaaataa gggtgttgac tacgagagct
    26041 tggatggaca agcaactgac ctcttcttca tgattgcagc tccagaaggt gccaatgata
    26101 ctcacttggc agccttggca gaattgtctc aatacttgat gaaagacggt tttgcagaca
    26161 aacttcgtca agcaacatct gcagaccaag ttatcgaact ttttgaccaa gcttcagaaa
    26221 aaactgagga acttgttcaa gcacctgcta atgactctgg tgactttatc gtagctgtta
    26281 cagcttgtac aacaggtatt gcccacactt acatggccca agaagccctt caaaaagtag
    26341 ctgctgaaat gggggttggt atcaaggtcg aaaccaacgg tgctagcggt gttggaaatc
    26401 aactaactgc agaagatatc cgtaaggcta aagctattat cattgcagca gacaaggccg
    26461 ttgaaatgga tcgatttgat ggaaaaccat tgatcaatcg tccagttgct gacggtatcc
    26521 gtaagacaga agagctaatt aacttggctc tttcaggaga tactgaagtc taccgtgccg
    26581 ctaatggtgc caaagctgca acagcctcta acgaaaaaca aagccttggt ggtgccttgt
    26641 acaaacactt gatgagtggt gtatctcaaa tgttaccatt cgttatcggt ggtggtatca
    26701 tgattgccct tgccttcttg attgacggtg ctttgggtgt tccaaatgaa aaccttggca
    26761 atcttggttc ttaccatgag ttagcttcta tgttcatgaa aattggtgga gctgcctttg
    26821 gtttgatgct tccagtcttt gcgggttatg ttgcctactc tattgctgaa aaaccgggtt
    26881 tggtagcagg tttcgtggct ggtgctattg ccaaagaagg ttttgccttt ggtaaaattc
    26941 cttatgccgc aggtggtgaa gcaacttcaa ctcttgcagg tgtctcatct ggtttcctag
    27001 gtgcccttgt tggtggattt atcgcaggtg ccttggttct tgccatcaag aaatacgtta
    27061 aagttcctcg ttcactcgaa ggtgctaaat caatccttct attgccactt cttggaacaa
    27121 tcttgacagg atttgttatg ctagctgtga atatcccaat ggctgcaatc aacactgcta
    27181 tgaatgactt cctaggcggt cttggaggag gttcagctgt ccttcttggt atcgtccttg
    27241 gtggaatgat ggctgttgac atgggtggac cagttaataa agcagcttat gtctttggta
    27301 caggtacgct tgcagcaact gtttcttcag gtggttctgt agccatggca gcagttatgg
    27361 ctggaggaat ggtgccacca cttgcaatct ttgtcgcaac tcttcttttc aaagataaat
    27421 ttactaagga agaacgtaac tctggtttga caaacatcat catgggcttg tcatttatca
    27481 ctgagggagc gattccattt ggtgccgctg acccagctcg tgcgattcca agcttcatcc
    27541 ttggttcagc agtagcaggt ggactcgttg gtcttactgg tatcaaactc atggcgccac
    27601 acggaggaat cttcgttatc gcccttactt caaatgctct cctttacctc gtttctgtct
    27661 tggtaggagc aatcgtaagt ggtgtggttt atggttacct acgcaaacca caagcataaa
    27721 aaatagaaaa atgaaaagat tggaccgttt ggtgcagtct ttttctcttc ccgaaatgcc
    27781 tgtgaaatat ggtataatag aagaatggca aacaagaata caagtacaac aagacggaga
    27841 ccgtctaaag cagaactgga aagaaaagaa gcgattcaac gaatgttgat ttcgttagga
    27901 attgcgattt tattgatttt cgcagccttc aaattagggg ctgcaggtat aaccctttat
    27961 aatttaattc gcttgctagt gggtagccta gcttatctgg cgatattcgg cctattaatc
    28021 tatctcttct ttttcaagtg gatacgaaaa caggaaggac tcttatctgg ctttttcacc
    28081 atatttgctg gcttactctt gatttttgag gcctacttgg tttggaaata tggtttggac
    28141 aagtccgttc taaaagggac catggctcag gttgtgacag atctgactgg ttttcgaacg
    28201 actagctttg ctggaggggg cttgatcggg gtcgctcttt atattccaac agcctttctc
    28261 ttttcaaata tcggaactta ctttattggt tctatcttga ttttagtggg ttctctccta
    28321 gtcagccctt ggtctgttta cgatattgct gaatttttca gtagaggctt tgccaaatgg
    28381 tgggaagggc acgagcgtcg aaaagaggaa cgctttgtca aacaagaaga aaaagctcgc
    28441 caaaaggctg agaaagaggc tagattagaa caagaagaga ctgaaaaagc cttactcgat
    28501 ttgcctcctg ttgatatgga aacgggtgaa attctgacag aggaagctgt tcaaaatctt
    28561 ccacctattc cagaagaaaa gtgggtggaa ccagaaatca tcctgcctca agctgaactt
    28621 aaattccctg aacaggaaga tgactcagat gacgaagatg ttcaggtcga tttttcagcc
    28681 aaagaagccc ttgaatacaa acttccaagc ttacaactct ttgcaccaga taaaccaaaa
    28741 gatcagtcta aagagaagaa aattgtcaga gaaaatatca aaatcttaga agcaaccttt
    28801 gctagctttg gtattaaggt aacagttgaa cgggccgaaa ttgggccatc agtgaccaag
    28861 tatgaagtca agccggctgt tggtgtaagg gtcaaccgca tttccaatct atcagatgac
    28921 ctcgctctag ccttggctgc caaagatgtc cggattgaag caccaatccc tgggaaatcc
    28981 ctaatcggaa ttgaagtgcc caactccgat attgccactg tatctttccg agaactatgg
    29041 gaacaatcgc aaacgaaagc agaaaatttc ttggaaattc ctttagggaa ggctgttaat
    29101 ggaaccgcaa gagcttttga cctttctaaa atgccccact tgctagttgc aggttcaacg
    29161 ggttcaggga agtcagtagc agttaacggc attattgcta gcattctcat gaaggcgaga
    29221 ccagatcaag ttaaatttat gatggtcgat cccaagatgg ttgagttatc tgtttacaat
    29281 gatattcccc acctcttgat tccagtcgtg accaatccac gcaaagccag caaggctctg
    29341 caaaaggttg tggatgaaat ggaaaaccgt tatgaactct ttgccaaggt gggagttcgg
    29401 aatattgcag gttttaatgc caaggtagaa gagttcaatt cccagtctga gtacaagcaa
    29461 attccgctac cattcattgt cgtgattgtg gatgagttgg ctgacctcat gatggtggcc
    29521 agcaaggaag tggaagatgc tatcatccgt cttgggcaga aggcgcgtgc tgcaggtatc
    29581 cacatgattc ttgcaactca gcgtccatct gttgatgtca tctctggttt gattaaggcc
    29641 aatgttccat ctcgtgtagc atttgcggtt tcatcaggaa cagactcccg tacgattttg
    29701 gatgaaaatg gagcagaaaa acttcttggt cgaggagaca tgctctttaa accgattgat
    29761 gaaaatcatc cagttcgtct ccaaggctcc tttatctcgg atgacgatgt tgagcgcatt
    29821 gtgaacttca tcaagactca ggcagatgca gactacgatg agagttttga tccaggtgag
    29881 gtttctgaaa atgaaggaga attttcggat ggagatgctg gtggtgatcc gctttttgaa
    29941 gaagctaagt ctttggttat cgaaacacag aaagccagtg cgtctatgat tcagcgtcgt
    30001 ttatcagttg gatttaaccg tgcgacccgt ctcatggaag aactggagat agcaggtgtc
    30061 atcggtccag ctgaaggtac caaacctcga aaagtgttac aacaataaaa aaatagcttc
    30121 tttccaagtt tggagggaag ctatttttct ggctattgat tacttttata ctcttcgcaa
    30181 atctcttcaa accacgtcag cttcgccttg ccgtactcaa gtactgtcta cggctagctt
    30241 cctagtttgc tctttgattt tcattgagta ttattttctg aagttggagt attgggctgt
    30301 ttttcatttt cagtggcagg tttacttgta gcaggtgtag tagagtcctg agttgctgtt
    30361 ttctgatctt cttttttctc ttccttgacg ctagattttg gcgtttcttc ttgttgtgtt
    30421 ttttcttgag aagtgttatt ttccttattt ggagtagtat tttcctgagg ggattctttt
    30481 tgaatttctt tgacaaaggt tgtcgtctgg cttgtcgtag gttctttttt agtattttta
    30541 ttattattat ccaaggcgtt catgatcgtg atacccgcgg taatcaaacc aaggatacta
    30601 ccgatagtag taatggtttt ttgaaaaaca gtaaagcctt ttttgatatg ttctgttttc
    30661 ggttttgaag ttctacgata gttagacata cattctctcc tttgattatg atttattata
    30721 ctctgtttct ttaaaaaaat cttaaaaaaa gagaaattgc cctttcttgt cgcaggctcc
    30781 gtttcatgat acaatagaag gagtgatttt agaaagcgtg agaaacatga tttactttga
    30841 taattcggcg acgaccaggc cctatccaga agcccttgaa acctatatgc aggtggcttc
    30901 aaaaatttta ggaaatccat ctagtctcca tcgtttggga gaccaggcaa cacgaatttt
    30961 agatgcttcc cgtcaacaga ttgcagattt aatcggtaag aaaagtgatg aaatcttctt
    31021 tacatctggt gggacagaag gggataactg gatcatcaag ggagtagcat ttgaaaaagc
    31081 ccagtttggc aagcacatca tcgtatcagc cattgaacat ccagcagtta aggaatcagc
    31141 cctctggttg aaagctcaag gttttgaagt ggattttgct ccagttgata acaaaggatt
    31201 tgtggatgtt gaggcgctag aagatttgat aagacctgat acgaccctcg tttccatcat
    31261 ggctgtgaac aatgaaatcg gctctatcca acctattgag gctatttcag aattcttggc
    31321 agacaagcca actatttcct tccacgttga tgcggttcag gcgcttgcca agattccgac
    31381 tgaaaagtat ctgacagaac gagtggattt cgcgactttc tctggtcaca agttccacgg
    31441 aatccgtggt gttggtttta tctatatcaa gtctggcaag aagattacgc ctcttttaac
    31501 aggtggtggt caggaacgtg attaccgttc gacaactgaa aatgtggcag gaattgcagc
    31561 gaccgctaag gctctccgtt tatctatgga aaagctagat atctttagga gcaagactgg
    31621 gcagatgaag gcagtgattc gtcaagcact tctggactat ccggatatat ttgtcttttc
    31681 agatgaggaa gacttcgccc ctcatattct gacttttgga atcaagggtg ttcgtggtga
    31741 ggtcattgtt cacgcctttg aagactatga tattttcatc tcaacgacct cggcttgttc
    31801 gtccaaggct gggaaaccag ccggaaccct gattgctatg ggagtggaca aggataaggc
    31861 tcagtcagct gtgcgtctta gtctagacct tgaaaatgat atgagtcagg tcgagcagtt
    31921 cttgaccaag ctaaaattaa tttacaatca aactagaaaa gtaagatagg agcattcatg
    31981 cagtattcag aaattatgat tcgctacggt gagctgtcaa ccaagggcaa aaatcgtatg
    32041 cgtttcatca ataaacttcg caataatatt tcagacgttt tgtctatcta tccccaagtt
    32101 aaggtaacag cagatcgcga ccgtgcccac gcttacctca atggagcaga ttacacagca
    32161 gtagcagaat cgctcaaaca agtatttgga attcaaaact tttcccctgt ttataaggtt
    32221 gaaaaatctg tagaagttct gaagtctgct gtccaagaga ttatgcagga catctacaag
    32281 gaaggcatga cctttaaaat ctctagcaag cgtagcgacc acacctttga attggacagt
    32341 cgtgaactca accaaacgct tggaggggct gtattcgaag ccattccaaa cgtacaagct
    32401 caaatgaaaa gtcctgacat caatcttcag gtggagatac gtgaagaagc agcctatctt
    32461 tcttatgaaa ccgttcgagg ggcaggtgga ttaccagtgg gaacttctgg taagggcatg
    32521 ctcatgttgt cagggggaat cgattcccct gtagctggct atctagcgct taaacgaggg
    32581 gtagatatag aggcagttca ctttgccagc ccaccttaca cgagtcctgg tgctcttaaa
    32641 aaagcccaag atttgacccg taaattaacc aaatttgggg gaaatatcca gtttatcgaa
    32701 gttcctttta cagagattca agaggaaatc aaagccaaag cgccagaagc ctaccttatg
    32761 accttgacgc gtcgttttat gatgcgtatt actgaccgta ttcgtgaggt acgaaatggt
    32821 ttagttatca tcaatgggga aagtctaggt caagtagcca gccaaaccct tgaaagtatg
    32881 aaggctatca atgctgttac caacactccc atcattcgtc ctgtggttac catggacaag
    32941 ttggaaatca ttgacatcgc ccaggaaatc gatacctttg acatttcaat ccaaccgttt
    33001 gaagactgtt gtactatttt tgcaccagat cgtccaaaaa caaatcctaa aattaagaat
    33061 gcggagcagt acgaagcgcg tatggatgtt gaaggcttgg ttgagcgagc agtggctgga
    33121 atcatgatta ctgaaatcac acctcaagcc gaaaaagatg aagttgatga cttgattgac
    33181 aatctgctct aattcagaaa atccaaaaga atagcgaaaa tcagtaaaaa aagttagttt
    33241 tttctctaaa aacaggtaaa aaactaactt tttttatttt tatgatataa tgatataaaa
    33301 ttttgaatat agagagtttt ctgacaatga atcaatccta cttttatcta aaaatgaaag
    33361 aacacaaact caaggttcct tatacaggta aggagcgccg tgtacgtatt cttcttccta
    33421 aagattatga gaaagataca gaccgttcct atcctgttgt atactttcat gacgggcaaa
    33481 atgtttttaa tagcaaagag tctttcattg gacattcatg gaagattatc ccagctatca
    33541 aacgaaatcc ggatatcagt cgcatgattg tcgttgctat tgacaatgat ggtatgggga
    33601 ggatgaatga gtatgcggct tggaagttcc aagaatctcc tatcccagag cagcagtttg
    33661 gtggtaaggg tgtggagtat gctgagtttg tcatggaggt ggtcaagcct tttatcaagc
    33721 acaaaacagg ttggtttgat ggcatgatga cgacaggttg ctctatggga gcctatcatg
    33781 cactcaattt cttcctccag catccagatg tctttaccaa agtgattgct ctcagtggtg
    33841 tttacgacgc acgtttcttt gtcggcgatt actacaacga tgatgctatt taccaaaact
    33901 cgccagtaga ttatatttgg aaccaaaacg atggctggtt tattgaccgt taccgtcagg
    33961 cagagattgt gctgtgtacg gggcttggag cctgggaaca agatggttta ccatcctttt
    34021 acaagctcaa agaagccttt gaccagaaac aaattccagc ctggtttgct gaatggggac
    34081 atgatgtcgc ccacgactgg gaatggtggc gtaaacaaat gccttatttc ctcggtaatc
    34141 tctatttata aaaggagtta cctatgaatt accttgttat ttctccctac tatccacaaa
    34201 actttcaaca gtttaccatc gaactagcta ataaaggcat cacagtcttg ggaattggtc
    34261 aagagtctta cgagcaattg gatgagccct tgcgcaatag cttgaccgag tattttcgtg
    34321 ttgataatct tgagaacata gatgaagtca aacgtgcagt tgcttttctc ttttataaac
    34381 atggtccaat tgaccgcatc gagtctcaca atgaatactg gcttgagcta gacgcaacac
    34441 tcagagaaca attcaatgtt tttggtgcca aaccagagga tctcaaaaag acgaaatata
    34501 agtctgaaat gaagaaactt ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta
    34561 tcaagacgga agcagatgtt gatcaagcag tgaaagaaat cggtcttcca atgattgcca
    34621 aacctgataa tggagtggga gcagccgcaa cctttaaact tgagacagaa gacgatatca
    34681 atcacttcaa gcaagaatgg gaccattcaa ccctttattt ctttgaaaaa tttgtcactt
    34741 ccagcgaaat ctgtaccttt gacgggctcg tggacaagga tggaaagatt gtcttctcaa
    34801 caacctttga ctacgcctat acaccgcttg acctcatgat ttataagatg gacaattctt
    34861 attatgtgct caaggatatg gatcctaaac tgcgcaagta tggggaagca attgtcaaag
    34921 aatttggtat gaaagaacgg tttttccata ttgagttctt ccgtgagggg gacgattata
    34981 ttaccatcga gtacaataac cgccctgcag gtggttttac cattgatgtt tataactttg
    35041 ctcattcctt ggacctttat cgtggctatg cagctattgt cgcaggagag gagttcccgg
    35101 cgtcagactt tgaaactcag tattgtttgg ctacttctcg ccgtgcaaat gctcactatg
    35161 tttattcaga agaggatttg cttgccaaat atagccagca gttcaaggtt aaaaaagtca
    35221 tgccagctgc cttcgcggaa cttcaaggag attacctgta tatgctgaca actccgagtc
    35281 gacaagaaat ggatcagatg attgctgatt tcggacaacg tcaagaataa gaactatcgg
    35341 attaaggaaa ttcactccct taatcctttt gttttgtctg gtaaaaaata agagcatcct
    35401 aacaaggtag ctatcataaa acttgttcga taactatttg aagcaggatt aggtggctag
    35461 aaattgaatt ttaacatttc aatttagtca tagtattgtg ttttcgtatc cttaaatcag
    35521 ctaaaaggat ccatgacgac acctatacga tatagttttc aggataccaa accagtctat
    35581 taatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac
    35641 tgttttgagg ttgtggatag aactgacaga gtcagtatca tatacctacg gcaaggtgaa
    35701 gctgacgtgg tttgaagaga ttttcgaaga gtataaaata ttcaggtgac gcatagatat
    35761 agttaattga agctttgttt gaaatctgat aaaataatga tattactaag ttttaaaaac
    35821 taaagaaaag ggaagatatg attacaggcg aattaaaaaa taaaatcgat cagctgtggg
    35881 aaattctttg gacagaagga aacgcaaatc ctttaacaaa tattgaacag ttgacttatc
    35941 tcttatttat gaaagatttg gatagtgtcg agcttggacg tgaaagtgat gctgaatttc
    36001 tagggattcc ttatgaggga gtttttccaa aagataaacc tgaataccgt tggtcaactt
    36061 ttaaaaatat aggagatgct caggaagttt atcgtttaat gactcaggag atttttccgt
    36121 ttattaaaaa tctcaagggg gatacagatg atacagcctt ttcacgatat atgcgagaag
    36181 ctatttttca aataaataaa cctgctacgc ttcaaaaggc aatttctatc ttagatgttt
    36241 ttccaactag gggattagat gtagattttg ataatgacaa acaaagtatt actgatatcg
    36301 gagatatcta tgaatatctg ttatcaaaat tgtcgaccgc aggtaaaaat ggacagttcc
    36361 gtacacctcg tcacatcatc gatatgatgg ttgagttgat gcaaccgact atcaaagata
    36421 tcatctcaga tcccgctatg ggttctgctg gcttcttagt atctgctagc cgttacttaa
    36481 agcgtaagaa agatgaatgg gaaaccaata cagataatat caatcatttt cataatcaga
    36541 tgtttcatgg aaatgatacg gatacgacta tgttgagact tggggcgatg aacatgatgc
    36601 tacatggagt agaaaatcca caaatcagtt accttgactc gctgtctcaa gataatgaag
    36661 aagccgataa atatactttg gttttagcaa atcctccttt taagggctca cttgactaca
    36721 attcaacctc taatgacctt cttgcaaccg taaaaaccaa aaaaacagaa ttactctttc
    36781 tttctctttt cttgcgaact ttaaaaccag gtggacgagc agcagttatc gtacctgatg
    36841 gtgtcctttt tggttcgtct aaagctcata aaggaattcg tcaggaaatt gtagagaatc
    36901 ataagcttga tgctgtaatc tcaatgccta gtggtgtgtt caagccttat gctggagttt
    36961 caactgccat tctcatcttt acaaaaactg gtaatggtgg tactgacaaa gtctggtttt
    37021 acgatatgaa agcggatggt ttaagtttgg atgataagcg acaaccgatt agcgacaatg
    37081 atattccaga tattatcgaa cgctttcatc atcttgaaaa agaagcagaa cgtcagagaa
    37141 cggatcaatc tttctttgtt ccagttgctg agataaagga aaatgattat gatttgtcta
    37201 tcaataaata taaagagatt gagtatgaaa aagttgagta tgaaccaaca gaggtcatct
    37261 taaagaaaat caatgattta gaaaaagaaa ttcaagctgg cttggctgaa ttagaaaaat
    37321 tactcaagta gggaggtggc tgtatgaaaa aagtgaagtt gggggaagtc ttatctctaa
    37381 aaaaaggcaa gaaagccact gtacttgctg aacaaacaac tctaagccaa cgttatattc
    37441 aaatagatga tttaagaaat aataataatt taaaattcac tgaaagttta aatatgactg
    37501 aagcactccc agatgatatt ctgatagcat gggatggagc taatgcagga acagttggtt
    37561 atggattatc gggagctgtt ggtagtacaa ttacggtctt aaaaaagaat gagcgataca
    37621 aagaaaaaat tatatcagat tacttgggag tctttttgga aagtaaatcg cagtatttac
    37681 gagaacattc aacaggtgca acaattcctc atttaaacaa gaatatatta cttgatttac
    37741 aattagaatt gctaggtatc gaagaacaag agaacattat ctgtattctt aatacgatta
    37801 aagggcttat tactaaaaga aaattgcagt tagatgaact aaacttgctc g
//
LOCUS       DAVBOH010000018        35443 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOH010000018 DAVBOH010000000
VERSION     DAVBOH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.018"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..141)
                     /locus_tag="VQ873_000976"
                     /pseudo
     CDS             complement(1..141)
                     /locus_tag="VQ873_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            127..612
                     /locus_tag="VQ873_000977"
     CDS             127..612
                     /locus_tag="VQ873_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3107253.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            696..1403
                     /locus_tag="VQ873_000978"
     CDS             696..1403
                     /locus_tag="VQ873_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107254.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1404..2735
                     /locus_tag="VQ873_000979"
     CDS             1404..2735
                     /locus_tag="VQ873_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3107255.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2902..3777
                     /locus_tag="VQ873_000980"
     CDS             2902..3777
                     /locus_tag="VQ873_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3107256.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3895..4758
                     /gene="pstC"
                     /locus_tag="VQ873_000981"
     CDS             3895..4758
                     /gene="pstC"
                     /locus_tag="VQ873_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3107257.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4751..5566
                     /gene="pstA"
                     /locus_tag="VQ873_000982"
     CDS             4751..5566
                     /gene="pstA"
                     /locus_tag="VQ873_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3107258.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5568..6320
                     /gene="pstB"
                     /locus_tag="VQ873_000983"
     CDS             5568..6320
                     /gene="pstB"
                     /locus_tag="VQ873_000983"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3107259.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6335..6985
                     /gene="phoU"
                     /locus_tag="VQ873_000984"
     CDS             6335..6985
                     /gene="phoU"
                     /locus_tag="VQ873_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3107260.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7053..7478
                     /locus_tag="VQ873_000985"
     CDS             7053..7478
                     /locus_tag="VQ873_000985"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107261.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7652..8032)
                     /locus_tag="VQ873_000986"
     CDS             complement(7652..8032)
                     /locus_tag="VQ873_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3107262.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8244..9260
                     /locus_tag="VQ873_000987"
     CDS             8244..9260
                     /locus_tag="VQ873_000987"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3107263.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9282..10181
                     /gene="galU"
                     /locus_tag="VQ873_000988"
     CDS             9282..10181
                     /gene="galU"
                     /locus_tag="VQ873_000988"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3107264.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10599..11531
                     /locus_tag="VQ873_000989"
     CDS             10599..11531
                     /locus_tag="VQ873_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107265.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(11634..12311)
                     /locus_tag="VQ873_000990"
     CDS             complement(11634..12311)
                     /locus_tag="VQ873_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3107266.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(12295..12834)
                     /locus_tag="VQ873_000991"
     CDS             complement(12295..12834)
                     /locus_tag="VQ873_000991"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3107267.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(12846..13976)
                     /locus_tag="VQ873_000992"
     CDS             complement(12846..13976)
                     /locus_tag="VQ873_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3107268.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFVGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITETAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(14044..14742)
                     /gene="dapD"
                     /locus_tag="VQ873_000993"
     CDS             complement(14044..14742)
                     /gene="dapD"
                     /locus_tag="VQ873_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3107269.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(14972..15883)
                     /locus_tag="VQ873_000994"
     CDS             complement(14972..15883)
                     /locus_tag="VQ873_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3107270.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(15948..18413)
                     /locus_tag="VQ873_000995"
     CDS             complement(15948..18413)
                     /locus_tag="VQ873_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3107271.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYSLLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            18555..19811
                     /locus_tag="VQ873_000996"
     CDS             18555..19811
                     /locus_tag="VQ873_000996"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3107272.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(19889..21952)
                     /locus_tag="VQ873_000997"
     CDS             complement(19889..21952)
                     /locus_tag="VQ873_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3107273.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21954..22232)
                     /locus_tag="VQ873_000998"
     CDS             complement(21954..22232)
                     /locus_tag="VQ873_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107274.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22384..23232
                     /locus_tag="VQ873_000999"
     CDS             22384..23232
                     /locus_tag="VQ873_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3107275.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23833..24405
                     /locus_tag="VQ873_001000"
     CDS             23833..24405
                     /locus_tag="VQ873_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107276.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(25449..27707)
                     /gene="glgP"
                     /locus_tag="VQ873_001001"
     CDS             complement(25449..27707)
                     /gene="glgP"
                     /locus_tag="VQ873_001001"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3107277.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(27733..29250)
                     /gene="malQ"
                     /locus_tag="VQ873_001002"
     CDS             complement(27733..29250)
                     /gene="malQ"
                     /locus_tag="VQ873_001002"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3107278.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGYVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            29800..31071
                     /locus_tag="VQ873_001003"
     CDS             29800..31071
                     /locus_tag="VQ873_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3107279.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            31182..32474
                     /locus_tag="VQ873_001004"
     CDS             31182..32474
                     /locus_tag="VQ873_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3107280.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            32476..33318
                     /locus_tag="VQ873_001005"
     CDS             32476..33318
                     /locus_tag="VQ873_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3107281.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            33571..34371
                     /locus_tag="VQ873_001006"
     CDS             33571..34371
                     /locus_tag="VQ873_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3107282.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            34381..35367
                     /locus_tag="VQ873_001007"
     CDS             34381..35367
                     /locus_tag="VQ873_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3107283.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT        10842 a         7482 c         6669 g        10450 t
ORIGIN      
        1 ttcgctaatt cttcttttag ggcgattgat ttgtacttcc gtcgcatcaa tcattaccgt
       61 gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacca ctttgaacaa gagttacttc
      121 aacccattgg ctccgacgga taaagaagac ttgataagaa ctctagagtt agctccccat
      181 gttgaaggtg gctattttag acaaacaaaa aaagcttcag acactataaa ccttgctggt
      241 aagggaaggg cgctttatac cagtatttat ttcttattag aagaaacgaa tccttcacat
      301 tttcaccgat tgacagcaga tgaaatctgg tattttcatg cagaatcccc acttactgtt
      361 cacatgatta cagcagatgg tcactacgaa gcagtcactt taggcctgga catatccaaa
      421 gggcaacaac ttcactactg tgttcctaag ggcactattt ggggatcaac agttgataag
      481 gatgatgctc tggtttcttg tcttgttgct cctggttttg aatttgagga ttttgaatta
      541 tttgaaaggg tagatctact ggcgacctat ccagagcaca aggagatgat tgagcgtttg
      601 accagatact agtctttata agcaaattta atctgattta gcaatgttag gatttctgat
      661 aattgtgtta taatgttacc aataggagat aatagatgac aaaacaagtc ttattagtgg
      721 atgatgaaga acacattctg aaattgcttg actaccattt aagtaaggaa ggcttttcta
      781 ctcaattggt aacaaatgga cggaaggcct tagctttggc agaaacagaa ccctttgatt
      841 ttatcttgct tgatatcatg ttaccacaat tagatggcat agaagtttgt aagcggctga
      901 gagccaaagg cgtcaaaact ccaattatga tggtttctgc gaaaagtgat gaatttgata
      961 aggttttggc cttggaatta ggggctgatg actacctgac caagcctttt agccctagag
     1021 aattactggc gcgtgtcaag gctgtcctca ggcgaactaa aggaaaacaa gaaggagatg
     1081 attcagataa tatcgctgac aattcttggc tatttgggac cttgaaagta taccctgagc
     1141 gtcatgaagt ctacaaggcg aataagttac tgagtttgac cccaaaagaa tttgaactct
     1201 tgctctatct tatgaaacat cccaacatga cactgactag agagcgtctt ttggaacgta
     1261 tctgggggta tgactttggg caggaaacac gtttggtgga cgttcatatt ggtaagttga
     1321 gggaaaaaat tgaagacaat cctaaagccc ctcaatttat tcgaaccatt cggggttatg
     1381 gttataagtt caaggagtta tagatgaaac gctaccttca attttggcta gtcaatctaa
     1441 gtgttagcct cattctgatt gcagggatgg cattaacttg gatcagtaaa ggcatcggtc
     1501 tctttcttct agccctttct ttgggactag gtggctactg gctcttttgc ctttggaaat
     1561 gggaagttgc ttttgagacc ttgcaccaac ctctcttgac cagtagtgaa tactttttag
     1621 aaaaagggca agaagactta aagtctttgg ctcagtatgt gtctggccta aaaaccaaag
     1681 tctcccaaca ggatcagcaa tacaaggacc tagccgaaac aatggaggtt cttctgtcgc
     1741 acctaaccat ggggacgttt ttagtttccg ctcaaggtca gatgttatta tccagtcgct
     1801 ctctgcctca ttattttccc gatgtggacg gcgacataag ttcacttgat gacctcaaac
     1861 ggatggatat tcggaattta gttcaccaag cctttgatca aaaaacaagg ttaaaacaag
     1921 aagtaagtgg gtttcatgag ggtgacttga ttttagaagt gacagcagtt cccgttttta
     1981 gccccaccca atctgtggaa gctgtgctcg tcttgctata tgatttaaca acgattagaa
     2041 cttatgaaaa gttaaattta gcctttgtct caaatgcctc ccatgaattg aggacaccag
     2101 ttacttcgat taagggcttt gctgaaacca ttaaggggat gtcagctgaa gaagaagcgc
     2161 tcaaggatga ctttctagac attatttaca aagaaagctt gcgtcttgag catattgttg
     2221 agcatcttct taccttatct aaggctcaac aaatgcctat acaatggacg accctttctt
     2281 tggcagaatt tgtacaggat ttgactcaaa gcttgcaacc tcagctcaag aagaaggatt
     2341 tacagctaaa ggtgcaggtg ccagatgatg tcaccctcgt atcagatagt caattacttt
     2401 cccaaatctt actcaatctt ttatccaatg ccatccgtta cactgaacaa gggggaaaaa
     2461 ttgaggtcaa gacccaaaag gtgaacgaag gcattaagat ttctgtatca gatacaggga
     2521 ttggtattag tcaattagag caggatcgta tttttgaacg tttttaccga gttaataaag
     2581 gtcgaagcag acaaactggt ggcactggtc ttggccttgc cattgtcaaa gaactcagtc
     2641 aattattagg tggccaagtc acggtgacga gtcagcttgg cagaggcagt tgcttcacga
     2701 tttttcttcc taaccaatct ttcgcacagg actaataatt tttaaagcta tttttaggag
     2761 cagccatttt tcaaaagtgg ctttttttga ttctttacac aatctttaca tgaatcaggg
     2821 ataaaccttt acaaagactt gttagactat aaatgtagta agcctacaca agaaaaatac
     2881 atagagataa aggtgattat tatgaaattc aaaaaaatac ttactcttgc agccattggc
     2941 ttatcaggat ttgggcttgt tgcctgtggc aatcagtcat ctacttccaa acagtcagct
     3001 tcaggaacga ttgaggtgat ttcacgagaa aatggctctg ggacacgggg tgccttcaca
     3061 gaaatcacag ggattctcaa aaaagacggt gataaaaaaa ttgacaacac tgccaaaaca
     3121 gctgtgattc aaaatagtac agaaggtgtt ctctcagcag ttcaagggaa tgctaatgct
     3181 atcggctaca tctccttggg atctttaacg aaatctgtca aggctttaga gattgatggt
     3241 gtcaaggcta gtcgagacac agttttagat ggtgaatacc ctcttcaacg tcccttcaac
     3301 attgtttggt cttctaatct ttccaagcta ggtcaagatt ttatcagctt tatccactcc
     3361 aaacaaggtc aacaagtggt cacagataat aaatttattg aagctaaaac tgaaaccaca
     3421 gaatatacaa gccaacactt atcaggcaag ttgtctgttg taggttccac ttcagtatct
     3481 tctttaatgg aaaaattagc agaagcttat aaaaaagaaa atccagaagt tacgattgat
     3541 attacctcta atgggtcttc agcaggtatt accgctgtta aggagaaaac cgctgatatt
     3601 ggtatggttt ctagggaatt aactcctgaa gaaggtaaga gtctcaccca tgatgctatt
     3661 gctttagacg gtattgctgt tgtggtcaat aatgacaata aggcaagcca agtcagtatg
     3721 gctgaacttg cagacgtttt tagtggcaaa ttaaccacct gggacaagat taaataaaat
     3781 gtttgctcca taaatctcta aagagatgca gacgtttcat cgtacaataa gataaagaag
     3841 gcaagtaggg aggtgtcgta tctcccttac tttcttcact agaaaggaca agatgtgaca
     3901 aaacaagcct tcaaagaagc agtttttagg gcaatttttt tcatgagtgc aacagtagct
     3961 gttgtagcta ttttgctaat ctgtttcttt atttttagta atggcttacc tttcatggct
     4021 aactacggct ttgcccgttt tttattaggc agtgattggt cgccaacgaa cattccggca
     4081 agctatggta ttttaccaat gatcgttggt tccttattaa ttaccttagg agcgattgtg
     4141 attggggtgc caacaggcat cttgacatcg gtgtttatgg tttattattg tccaaagccc
     4201 gtctatggct tcttaaaatc agctatcaac ttgatggcag ccattccatc tattgtttat
     4261 ggttttttcg gcctacaatt attggtgcct tggattagaa cctttttagg aaatggcatg
     4321 agtgtcctaa ccgcttcgtt actattagga ataatgattt tgccaaccat tatcagtttg
     4381 tcagaatctg ctatccgaac agttcccaaa acgtattatt ctggtagctt ggctctagga
     4441 gctagtcatg aacggagtat ttttagtgtc atcttgccag ctgcgagatc tggtatttta
     4501 tcagcagtta ttttaggaat cggtcgcgca gtaggtgaaa ccatggcagt tattttggtg
     4561 gcaggcaacc agccaattat tccaagtgga ctcttttcag gaaccagaac cttaacaacc
     4621 aatattgttc tggaaatggc ttacgcatca ggtcagcata gggaagccct tattgcaacc
     4681 tcagcagttc tctttttcct tattctcttg attaatgcct actttgccta cttgaaagga
     4741 aaatcatctt atgagtaaat acctgctaaa acttctcgtt tattgttttt cagctttaac
     4801 ctttggctct ctctttttaa tcattggttt tatcctcatc aaaggcttac ctcatctaag
     4861 tctatccctc ttttcttgga cttatacttc tgagaacatt tcccttatgc cagcgattat
     4921 ttccaccgtt attctggttt ttggtgctct tcttttagct ttgcccatag ggatttttgc
     4981 tggtttttat cttgtggaat atacaaaaaa agattccctt tgtgttaaaa tcatgcgatt
     5041 ggcctcagat accttgtctg ggattccttc cattgttttt ggtctgtttg gcatgctctt
     5101 ctttgtagtc ttcttaggtt ttcaatactc tctgttatca ggaatcttaa cctcagttat
     5161 catggtgttg ccagtcatta ttcgctcaac agaagaagcc cttttatctg ttagtgatag
     5221 catgcgtcaa gcaagttatg gacttggggc aggtaagtta cggactgttt ttagaattgt
     5281 tctaccagtt gccatgccag gtattttagc tggagtgata ctagctattg gccgtatcgt
     5341 tggtgaaaca gctgccctca tgtatacatt aggtacctct accaatacgc caagtagtct
     5401 catgtcttca ggccgttctc tagccctaca tatgtatatg ctgtcaagtg aggggctaca
     5461 tgtcaatgaa gcctatgcta ccggcgtgat tttaattatt actgttttaa tgataaatac
     5521 tctatcaagc ttattatctc ggaaacttgt gaaaggagct tcctagtatg ggaacatttt
     5581 cagtcagaca cctagactta ttttacgggg attttcaagc cttaaaaaat atttcgattc
     5641 aattaccaga aagacagatt actgccttga taggcccatc tggttgtggc aaatcaactt
     5701 ttctaaaaac ccttaaccgg atgaacgatt tggttccttc ttgccatatt gaaggccaag
     5761 tcctcttaga tgagcaagat atttatagta gcaaattcaa ccttaatcag ctacgtaagc
     5821 gtgtagggat ggtttttcaa cagcctaatc cctttgccat gtctatctat gataacgtgg
     5881 cttatggccc aaggacacat ggtattcgag acaaaaaaca attagatgcc ttagtggaga
     5941 aatctttaaa aggggcagcc atttgggaag aagtcaaaga tgatcttaaa aagagtgcca
     6001 tgtccttatc tggcggtcag cagcaacgcc tttgcattgc gcgagcttta gcagtagaac
     6061 ctgatattct gttaatggat gagccgactt cagccttaga ccctatctcc actttaaaaa
     6121 ttgaagacct cattcagcaa ctaaaaaaag attatacgat tatcattgtt acccataaca
     6181 tgcaacaagc ttcacgtatt tcagataaaa ctgctttttt cttaacagga gaaatttgcg
     6241 aatttggaga taccgttgac gtgtttacca atccaaaaga tcagcgcaca gaagactata
     6301 tttcaggacg gttcggataa ggaaggaaaa acctatgaga aatcaatttg acttagaatt
     6361 gcatgaatta gaacaatcct ttttaggact agggcaactt gtccttgaaa cagcttcaaa
     6421 agccttactg gccttagcct ccaaagacaa ggagatggca gagctaatta tcaataagga
     6481 tcatgctatc aaccaaggtc aaagcgctat cgaattgacc tgtgcccgtt tgttggcctt
     6541 gcagcagcca caagtgtctg accttcgatt tgtgattagc atcatgtctt cttgttcaga
     6601 ccttgaacgt atgggagacc atatggcagg cattgccaaa gctgttttgc aactaaaaga
     6661 aaatcaacta gcccctgacg aagaacagtt acaccaaatg ggtaaattat ccctcagcat
     6721 gctatccgat ttattggttg cctttccttt gcaccaagcc tcaaaagcta ttagtattgc
     6781 tcaaaaagat gaacagattg accaatatta ttatgcctta tcaaaggaaa tcattggact
     6841 tatgaaagac caagaaacct caattcccaa tggaacacaa tacctttata tcatagggca
     6901 tctggaacgc ttcgctgatt acattgctaa catttgtgaa cgcctagtct acctagaaac
     6961 aggagaacta gtggatttga attaattcaa ctaatcctta aaagagaaga gtacgattaa
     7021 gtgctctttt ttatggttgt aaaaaagttc atttgaccaa tttaagcagt gtagatagtg
     7081 aggagctgtt tcaattctat cgtgaacgag ggaatgctga aaactttatc aaagaaagga
     7141 aagcaggatt ctttggggat aagacagata gttcgaccat gattaagaat gaagtacgta
     7201 tgatgatggg ctgtctggct tataatctct acctcttttt aaagcagcta gctggtgatg
     7261 aagtaaaggc cttgactatc aagcgttttc gacgtctctt ccttcatatt gccggaaaat
     7321 atgtctctac tgctagacga catattctca aattctcaag tctatatgcc tattcaaaac
     7381 agtttcaagc cttatttgat acaatctgcc agataaatct gatactccct gttccatata
     7441 gagctagagg gcaggggaaa acatgcctaa cagaataagt caccttattt taaaaatcga
     7501 gcatcaaacc aagggaggag tctgcccttt tttaggaaaa aatcaagaca aatctcctca
     7561 attatgtctc taacatcaga aattaagcaa aatcaccaga aggacagtat ttcaactagc
     7621 ttttctggta atttttgaac tgtgtagttc gttagtgcca gatatgaata atttgggatg
     7681 ataaatcttt cttcctcagg tagcctatca taatactctt caaaaatctt atcaaaacac
     7741 tctctttctt ttgggcgata gtttcatctt cgtatgtagg agtcctcatc aagaaatact
     7801 tcaattctag gtattcctta tccaactcta tataacttgg catcaacttg taatcctcaa
     7861 cccccaaacg ttcagcgata tattttaact ttgttagtgt tggtctggat tctccatttt
     7921 caattctaat taattgacgg atacttaatt cagactcatc accacaaaat tctgaacgac
     7981 tgattttttt agccaaacgt aatcttttaa ttttttcgcc aaactctcgc aacctacaag
     8041 aacctcctga gttgtttacc tctattataa gcatatactg aatcaaacta tctatcagat
     8101 ttcttctcac tttaactaaa gactaagagt ttatcccttc atctcggtct ttgtgtattt
     8161 ttccaccata ccccagtaat gcaagtgcaa aatcctctag aatatgatag aataatggaa
     8221 agaactctat caaggaggaa atcatggaaa aacaaaccgt cgccgtcttg gggcctggtt
     8281 cttggggaac tgccctttca caagtcttaa atgacaatgg acacgaggta cgtatttggg
     8341 gaaatcttcc cgagcaaatc aatgaaatta atacctatca tactaacaag cactacttta
     8401 aagatgtcgt tctagatgaa aatatcattg cctacaccga cttagcagaa acattgaaag
     8461 atgtggatgc gattttgttt gttgtcccaa caaaagtgac acgacttgtt gcccaacaag
     8521 ttgcacaaac cttggaccat aaggctatca tcatgcacgc ttcaaaggga ttagaacctg
     8581 atagccataa acgattatca actatccttg aagaagaaat tcctgaacag ctccgcagtg
     8641 atattgtcgt tgtttcaggg cctagtcatg cggaagaaac cattgtgcgt gacctaactt
     8701 taatcactgc tgcttctaaa gatttacaaa cagctcaata cgttcaggag ctatttagta
     8761 atcactactt ccgactttat accaatacgg atgttatcgg ggttgaaact gctggtgctc
     8821 ttaaaaatat tattgctgtc ggtgctggag ctttacatgg tcttggattt ggtgataatg
     8881 ctaaggcagc catcatcgct cgaggtttag cagaaatcac ccgcctaggg gtagcactcg
     8941 gggccagtcc attgacctat agcggcttat ctggtgtggg agatttgatc gtaacgggaa
     9001 cttccatcca ctctcgtaac tggagagctg gagatgctct cggacgagga gaatccctag
     9061 ctgatataga agctaatatg ggcatggtaa tcgaaggaat ttcaacgact cgagcagcct
     9121 atgaactagc ccaagaactt ggagtctata tgcccattac acaggctatt taccaagtta
     9181 tttatcacgg aaccaatatc aaagatgcca tttatgacat catgaacaat gaatttaaag
     9241 cagaaaatga gtggtcttaa ccctctatag aaaggatttt tatgacatca aaagttagaa
     9301 aggcagtcat ccctgctgct ggactaggaa ctcgattttt accagcaacc aaggcccttg
     9361 ccaaagaaat gttgccaatc gtagacaaac caactatcca gtttatcgtg gaagaggctc
     9421 tcaaatcagg tattgaagat attctagttg tcactggtaa atcaaaacgt tctattgagg
     9481 accactttga ttcaaacttc gaattggaat ataacctcaa agaaaaaggg aaaacagatc
     9541 ttttgaagct agttgatgaa acaactggca tgcgtctgca ttttatccgc caaactcatc
     9601 cacgcggtct cggagatgct gttttgcaag ccaaggcttt cgtcggaaat gaaccttttg
     9661 tcgttatgct tggtgatgac ttgatggata tcacagacga aaaggctgtt ccacttacca
     9721 aacaactcat ggatgactac gagcgtaccc acgcgtctac tatcgctgtc atgccagtcc
     9781 ctcatgacga agtatctgct tacggggtta ttgctccgca aggcgaagga aaagatggtc
     9841 tttacagtgt tgaaaccttt gttgaaaaac cagctccaga ggacgctcct agcgaccttg
     9901 ctattatcgg acgctacctc ctcacgcctg aaatttttga gattctcgaa aagcaagctc
     9961 caggtgcagg aaatgaaatt cagctgacag atgcaatcga caccctcaat aaaacacaac
    10021 gtgtatttgc tcgtgagttc aaaggggctc gttacgatgt cggagacaag tttggcttca
    10081 tgaaaacatc catcgactac gccctcaaac acccacaagt caaagatgat ttgaagaatt
    10141 acctcatcca acttggaaaa gaattgactg agaaggaata acaaaatcat ttatataaag
    10201 attagccaca cataaattaa gtaaattctc tacttgaatc tacctattta ataaaaacta
    10261 atgaaaacgc tatacttgta tttgtttttt cattaaaata agagtagaat aaattagtat
    10321 agtaaaacaa aaaagcaccg aatcggtgcg cactttttca agttgtgtac ggacaaagcc
    10381 ttattttaac tttgctatgt tgtttcgaat ggttccaaaa taataaataa ttttaaattt
    10441 gacttaactg ttggagtagt catggttaaa ttaaatcaac cgagccgaac ataagttgtt
    10501 taattttgtg gaagctatta ataaaaatat aataagggag aaagataggt gtaattttaa
    10561 ttttaaagta attgcggaca ctatcaaagt aaaagattat ggagaacaaa tttgtagaat
    10621 ttatcgaaaa caataaaaaa gtaatcattt catcagttgc agttggtgtt gtattggtat
    10681 tagggtttgg atggtattca tataaccaac aacaagcaga acaacaagca aaaattgtac
    10741 aattagaaaa agatagcaaa tcagacaaag aacaagttga taaactattt gaatcatttg
    10801 atgcatcttc agatgaatct atttctaaat taaaagaact atctgaaact tcacttaaaa
    10861 ccgatgcagg taaagactat cttaataaca aagtcaaaga atcatctaaa gcaattgtag
    10921 attttcattt gcaaaaaggt ttggcttatg atgttaaaga ttcagatgac aaatttaaag
    10981 ataaagcaac cttagaaaat aatgtaaaag aaatcaataa acaaattgat tttatcaaga
    11041 aagttgatga aactttcaaa caaaaaaaat tggatgaaac tgtaaaatct cttacagata
    11101 ttgcagacaa attccaaaaa caaattgatg ttctgaagaa agaagaagaa caaaaagcat
    11161 ctgacaaagc taaagaagat aagaagaaag aagaatcaac ttcatctcaa tcttcaaata
    11221 gttcatctca agcatcaagc agttctttta gttcatattc tggtaattca gattatgctc
    11281 cagaacaaac atacacagct gataatagcc aatcttattc aggttcaact ggtggagaca
    11341 atagtaacta taaagcacca gctgctacag acaacggagg aaatgatggc tatattcttg
    11401 ggcacgtaac tggtgcagat ggatcgcaaa gagattttta ttttaaccgt tcaaacggag
    11461 atgttcgtga tacaagcggc aatcacgtag gaaactttgg agggggcatt acagatttta
    11521 gacaacgtta ataactattt tagggctgtg ttgtttcgaa tggttccaaa acacattaaa
    11581 agctactcat tttttaagta gcttttttct tattcaagtt tacatattag ttgtcacaac
    11641 cccattccct tgtagaaaag caaaatggcg agtcctacga acaagactac cgctcctaat
    11701 ctctggctgg tattatacat ccgtttttct cctctaactg gaaagataac tgctagaaat
    11761 gcgccaccaa ctgcaccacc gatatggcct gctaggctga ttcctggaat cagaacactt
    11821 ccaataatgt taaccacaaa aagtgtcaga taggattgcc ctagctgttg gatataagga
    11881 ttgcgagttg catagcgaag aacaataatc gcggcaaata gcccataaag agaggtagag
    11941 gcgcctgctg ctaaggattt aggactaaat acaaaaacaa agagattgcc catcattcct
    12001 gataagagat agagaaaaaa gaactgctta gagccgaaaa tctcctctac ctgccttcca
    12061 agataataaa gtgaaagcat attaacaatg aaatgttccc acccaatatg aacaaaaatg
    12121 gcagacaaga gacgccaaac ctgctcggga aagaggcgaa tagctggccc atacatggct
    12181 ccaaatcgaa ataatgtatc tgccctgtca aagtttccgc ctgcagtgac caacattagt
    12241 aaaaatacca aggccgtcac taagaggaag aaactcgtca cagggtaacg tctatcaaag
    12301 atttccttca tcaattaata cctcctgaac aggaatatca tggttttcag gtataaagtc
    12361 ctgaatttga caaggatata tcgtactcaa agtacgacca gaaaaatgtt ccaaatagcg
    12421 gtcataatag cctccaccgt atcctatccg atatcctttc gtcgtaaaag ccagaccagg
    12481 aacatgaatc aaatcaatct gagatgcatc caccacttcc acatctccct gtggctccag
    12541 taaggcaaag gcagttttta ccaactgttg cggatcatag accacaaact ccatgcgccc
    12601 cttgggataa gttttgggta ttaaaacctt cttgccgtcc ttcagcgcct gctcaatcag
    12661 ttcccgcgtt tgaaactcat gagaaaaaga gaggtaggtt gcgatgacct tggcttcttg
    12721 gtagaaggga tggtgtaaaa gccgctcggt taaagcttgg tctatagcct gtttttgctc
    12781 ttgagatata gccttcattt catgcaagac ttgcttgcgt aattccgatt tcatagacaa
    12841 gccctctatt ctgctgcctt ctttttcagg aaactagaca ccgcagccac cccaatagct
    12901 aagacttctt ccttaggact catttgaggg tgatgaagag cgtagggact atcgataccc
    12961 agccaaaaca tcacgccatc aacctttgaa aggagataac caaagtcctc gcctgtcata
    13021 gcaggttcga tatcaatcaa ctcgattccg tctttttcgt caaagaagtc catcagttca
    13081 cgcgccaagg ctggattgtt ctcaacaggt aggtatccac cttgtttgag ttccacttcg
    13141 acttccatat caaaggcagc tgcaacccct tctgcaactg tttttaccct cttttgcacc
    13201 aagagactca tgtcctgtgt caaggcacga atagttccat gtaaaaaagc tgtttctgtg
    13261 atgacattgt tggtggttcc agcttgaaaa acgccgaagg tcaccactgc tccctcgatt
    13321 gggttgacat tgcggctaac aactgactgc acttgggtca caaagtaact agccgctacc
    13381 aaggcgtcat tggcttcatg aggaaaagct gcgtggccac ctttgccttt gaaacggatc
    13441 ttcacctcgc aagttcctac aaagagtgta tgagtattag tcgcaatctg gccgactttc
    13501 aaatctggac gaacatggag accatagaat tggtttggca accaatctcc aaaagcaccg
    13561 tcctcataca tgagcatacc accagcttca ttttcttcag caggctgaaa tagaaagagc
    13621 agattattct tgggttgctc ctcaagggcg cgctcaagac agcctaaggc aatggtcata
    13681 tgaaaatcat gaccacaggc atgcatgcga ccttggtgtt gagaagcaaa aggtagacct
    13741 gtttgttcga cgataggcag gccatcaata tctgtccgcc aaccaatggt tcgctccggc
    13801 tgacttccct gcaggtagac caaaatccct gtccgccaag tacgaatttg aacaaaatcc
    13861 ttgcccgtag tcaatttctc aatcacatcc agcaaataag cctgagtctt gaactcctcc
    13921 aagccaatct ctggtatctg gtgtaaatct cgtctagtct gaatcaaatc taacatctat
    13981 ctgtcctccg atatagcaga aagaggctgg aaaaagggtt ccgcctcttt tttactttta
    14041 caattacaag gtacgaagcg catcctctag cgctgttttt tgttgggttt gggcatcaat
    14101 ttctttgatg atacgagctg gaacacctgc tactaccacg ttttctggga catcttgggt
    14161 aacgatagct cctgcagcga caactgaacc actaccgatt tggactcctt cgataaccac
    14221 tgcattagca ccgataagaa cattgtctcc gacacggact ggttcagcac tagctggctc
    14281 aatcacacct gccaaaactg cacctgcacc aacgtggcta ttttttccaa cgatggcacg
    14341 gccaccaagg atggcaccca tgtcaatcat ggttccagca ccgatttcag caccgatatt
    14401 gataacagat cccatcatga taacagcatt gtcaccaatt tccacctggt cacggataat
    14461 agcacctggc tcgatacgag cgttgatagc acgcttatct agcaaaggaa ctgcagaatt
    14521 acgagcatct tgctcgacaa cataatcttg attttctacc aaaccttcaa gaagcggagc
    14581 cacgtccttc cagtctccga ataggacatt tcctagtttg acaacagagc taggcacagc
    14641 agttgcgagt tgcccctcaa aggttacttt gacactggtt ttcttttcag cattggcgat
    14701 aaattggata atttcttgag cgttcatttt tgtagcagtc ataggtgcct cctggttcgt
    14761 tataatgata cctattctac caaaaaaggc ctcaaatttg aaaccttttt gtctgttttt
    14821 aggtatgatt ttttagggat gtgagataaa acgtgctgtc ggtaaaagca agcccctacc
    14881 gatacaacct aaaaacactc ttcacaacta tctccccgtg ttttattgac tattctagta
    14941 tagcacactt ttagaattaa gaaaagactt tttatctact ttctttcgct tcttctatag
    15001 acaaaaatat catgggtaaa ataatcaagg ctatagctag aaggagggac caatccacta
    15061 ctaatcctaa gaacaaaaca ctcaagagag cagaagagag aggttcactg gcactgataa
    15121 cggcaaccac caaaggagaa accaaggaca cagccttcat ggaaatgaaa aaagcaaaag
    15181 ccgttccaaa gaaagcgata atgaggcaaa tcaagatact ccaaatatca agagtaaagg
    15241 aaagctgata aaccggcgag aggacattgc taaacaaacc tgccaaaatc atcccccacc
    15301 caaccgtagg aacaaaacca taacgcttag caaaaggttg gggcaagata acattaaaca
    15361 taacacccat ggcactcagc aaacctgtta taagagctag cggcgtcatg gataactgag
    15421 agagatctcc ctttgtcgcc atcaagcaaa cacccagcat ggcaaccaaa acatagaaaa
    15481 cagcgctttt tgacgctcgt ttttgataaa ccaagcgatt gtaaaagagg ataaagacag
    15541 ggctaataaa ctgtaaaata gttgctgtcg tagcatttga gtattctaca cagagataga
    15601 aaaaatactg gactgaaaaa atccccaaaa tagcataggc taaaaagggc aggtaatttt
    15661 tcttgtctcg ccaaatatct agcacttgcg attttaattg tattgcagac caaatgagta
    15721 caatactccc tgccagtgtc aaacgcatag aggtaatcca gcccgaagac acctgataat
    15781 gagtaaagaa gtactctcct aaaattccac agattcccca tattaagccg gataggagcg
    15841 aataaatttt tccgttaaca atctttttct gatactgatt cataccctta ttgtaacacg
    15901 aaaggaaaaa agtggcaatc cattgattgg ccacttcatt tagagaatta tcgtctcgcc
    15961 cttgaagaag aaggtcgtgt agtacttgag ttactgctat cgctagaact actacttgaa
    16021 ctgctggagc tggatggagt tggtagactc cccacaatac tagaccaagc attctgataa
    16081 tccgcatcac ttccgccaat agcaaagcga taacttgtcg ctggcgctcc tgacttatta
    16141 gcccaatagc tggtaacagt cgaacctgtg acctctacct cttttccttc aacagaaacc
    16201 ttccctggtt tttgacctgt tgatttcaag acttccgatt tcactacact aggatctaaa
    16261 gcaaagcgct cgttccccca aatgcttggg gaagcttgct gaatcgcatt tactagatga
    16321 gccatgtaat tagagttatt agaataacct gctctacgtg acaatgaatg attatcatca
    16381 tgcccaatcc agccacctag ggttaatcta ggtgtcgaaa gcatgagcca catattttcg
    16441 tcttggttgg ttgtaccagt cttcccaatc caatctgcat tagccagagt aggatttaaa
    16501 gaagtcaggt tagacttgaa ggttgttgtc acacgagagg atagaacttc tcgtagcaat
    16561 ccctgcataa tcgtcgcagt agcttttgaa tagacttgaa ccggtttatc ctgatactca
    16621 tacaccactc taccatctgc tgcttcaatc tttgaaatca catgcttctg atgataaact
    16681 ccattattag ctaaggtctg atagccattg gtatgctggg caactgtgac ttcaatacca
    16741 ccacccattg gcaagctctc aataccgtac tcaggaatct cgtaacccat cttttccata
    16801 taacccttga catcaacacc attttcacgg agcagactat aggtccagta agcagggata
    16861 ttccatgagt agttcagagc ttctcccaag gtcatcattc ctgttccctt gctattagca
    16921 tacataatcg gattgccatt agcaaagttt gttggatagt tagatagaat cgtttcactt
    16981 cccatcaagc cctggtcaat agcaataccg taggccagca agggcttggt agtagaagct
    17041 ggcgaacgtt tggtatcaaa ggcatgatta ttttgatttt cttgataatt acgaccacct
    17101 acaaagccta gaatagcacc tgtttggttg tccatcaaga cattccctac ttctacacga
    17161 cctgttccat cgtctaaaag atagccataa tcagcaaccg cactttgcat ggcagaatga
    17221 attttctgat ctatggtagt agtaatctta taaccaccat tttcaatttc cttggctgcc
    17281 aaatctcgat aaaacttctg agttgcctca tttttcaact ccttagcgga gacattgtct
    17341 ctctgagcta gatagtcata catacgttct tgagcttctg ccaaagttgt aaagtataaa
    17401 tagtctcgtg aaattcctgt aaccgtgccc gatggtaaaa agtcctgttt aaggtcataa
    17461 tccttgtact gagaatactc gtctttgctt aatgcacctg tacgatacat actgtaaaga
    17521 actgccttag cccgtcttaa gccaatttct aggtcttcat cactcttcaa ctccccagta
    17581 ttttcataag gagagtaagt aatgggactc tgtggaagtc ctgctaaaaa tgctgcttga
    17641 ggaacagtca actgactggc atctacaccg aaaattccct cagctgcttg ccgagcccct
    17701 gcaatattct gtcccttatt atttcggcca aagggagcca cattgagata ggtcgttaaa
    17761 atctcatctt tattcatggc gcgttccaag gcaagagcat ccacaatctc tgccgcctta
    17821 cgagccaagg tcggcgcatc cccaaccacc tgctgtttaa ttagttgctg ggtcaaggtt
    17881 gaacccccac tagaggaacc caaacctaca aatttcccca aggtcgcacg aatcaccgcc
    17941 ttgggtacta cacccttatg ttctttaaag tgttcatctt ctgtcgcaat gatagccttc
    18001 ttcagatttt ccgaaatttg ctcagatgag atagaagtgc gcaacaaatc actctctatg
    18061 gaagcaatca ccgtcccgtc cgaataggta atctctgaaa tagaagagat gtccttgacc
    18121 tgattcacca attcttctgt ctgaggcacc cgaaccttgt caaataaggc cactccgtac
    18181 cccaaagcaa tcccagctcc caacattcct cctagaaaac cgagtacaaa gagtaagtta
    18241 aataaggctt ttatactcag taaaatagct gggaaaatgg ctgacttatc taaggtttta
    18301 gattttttgg tacttgaacc tttcttgcca ggtctagctg attttttatt tttttgtttt
    18361 tgctggaaaa attccagcat ttttcgtttt aattcattta attgattttg catggatttc
    18421 ctcactttat ctattatacc acaaaaggga aattttcaat aaaatagcca ctttcttccc
    18481 tattctgcta ggctattgcc caagtttgtg atacaatagg tagaaacaat aattttaaaa
    18541 aggagaaaaa acacatgcac atttttgatg agctaaaaga gcgtggtttg atatttcaaa
    18601 cgactgatga agaagctttg cgtaaagccc tagaagaagg tcaagtttct tattatactg
    18661 gctacgatcc aactgctgac agccttcacc taggccacct tgtcgcaatc ttgacaagtc
    18721 gtcgcttgca actagcaggt cacaaacctt atgcgctcgt tggcggtgct acaggtctca
    18781 tcggagatcc gtccttcaaa gatgctgaac gtagtctcca aacaaaagac acagtagatg
    18841 gctgggtcaa gtctatccaa ggacaacttt ctcgttttct tgactttgaa aatggcgaaa
    18901 acaaggctgt catggtcaac aactacgact ggtttggcag catcagcttc attgacttcc
    18961 tccgtgatat tggaaaatac ttcacggtca actacatgat gagtaaggaa tctgtaaaaa
    19021 aacgaatcga aacaggaatt tcttacactg agttcgctta ccaaatcatg caagggtacg
    19081 acttcttcgt ccttaaccaa gaccataatg tcactcttca aatcggtggt tctgaccagt
    19141 ggggaaatat gacagctggt accgaattgc ttcgtcgtaa agcggacaag actggtcacg
    19201 ttatcactgt tccactaatc acagatgcaa ctggtaagaa atttggtaaa tcagaaggaa
    19261 atgccgtctg gctcaatccc gaaaagactt ctccatacga aatgtaccaa ttctggatga
    19321 acgtgatgga cgctgacgct gttcgcttct tgaaaatctt tactttcttg tcacttgatg
    19381 agattgaaga tattcgtaaa caatttgaag cagcgccaca cgaacgcttg gctcaaaaag
    19441 tcttggctcg tgaagttgtt acacttgttc acggagaaga agcctacaaa gaagcactta
    19501 acatcactga gcaactcttt gcaggaaaca tcaaaaacct ttctgtcaaa gagctcaaac
    19561 aaggacttcg tggtgtgcca aactaccaag tacaggcaga cgaaaacaac aatatcgtgg
    19621 aactgctcgt ctcatctggt atagttaact caaaacgcca agcccgtgaa gacgtccaaa
    19681 acggagccat ctacgtaaac ggcgaccgca tccaagagct tgactatgtc ttgagtgacg
    19741 ctgataagtt agagaatgaa ctgactgtta tccgtcgtgg gaagaaaaaa tactttgtat
    19801 tgacttacta aactattcaa catttatcta taaacaaagg agttagcctc gagaaaggta
    19861 actccttttt gctgttaata actctcatct atctattttt aatagacagg ctacgcagga
    19921 caatgcgcaa ggttgttaga ttatgtaaga tagagagatt tgaaggactg agccaattaa
    19981 ataagccgaa gccaatcaaa ctactattta cgacaacggt atcttgaata tttttcttga
    20041 tgagtgtttg caaagatgat gataacgaat ccaactcttg gaagaaatcc aaacgattat
    20101 ctaacaataa gatatcactc atctgcttag aaatatctgc actctcattc atcaccacac
    20161 cgatatctga tagagttaaa gccgctgagt cattcaatcc atctccaacc atcaaaatag
    20221 tgtgacctgc tttctgcagt ttctctacta actcaaattt cccatcaggt ttcaagtctg
    20281 tatagacctg atcaaagggc aaatctttga ctaattcctc tgtcctagtc aaggtgtctc
    20341 ctgttgccag aatcaatttt ttcccctgtg ccttaagttt atccaaggct gtttttgctt
    20401 cttttctcaa aggagtatga atgcagaaca ttccaatcaa ttcattttga taagccaaga
    20461 ataagagatt gtagtgactc ttgtactctt caattaaagc attttgttct gaactgatat
    20521 gaatctgctc atcctgcatc aagacataat tcccaataag aactggttgg ccatctatat
    20581 gagatttgat ccccttgctt gcgatatatt ggagtttccc atgcatttcc tcatgttcaa
    20641 ttccctctat ctcagcttgc ttgacgatgg cattagcaat aggatgataa atgtgttcct
    20701 caagacaggc actgattctg agaatatctt cctcactata gtctccaaaa ggtaacacct
    20761 tttcaactat aggataacta gttgtgattg ttcctgtctt atcaaacaag aaagtatcaa
    20821 cttccagata tttctccaga acatctccat ccttaatcac catttcacgg ttcaaccctt
    20881 ccttgataac tgtcaaataa gctacaggag tagagatttt caaagcgcag gagaaatcga
    20941 ccaataggaa agaaatagcc ttagaaaaag aacctgtcaa taggtaagtc agcccagacc
    21001 ccaagaaatt atatttgacg actttatccg ccatcttgat gaaatagcgt tgtttcgttt
    21061 tcttgttttc ttcagatttc ttcatcaact caatcagctg taaaatacgg ctgttcatct
    21121 gattatctgt tacacgaatg cgtaactctc cagtttctaa tactgtattt gcacaaacca
    21181 aatcagactc tcttttttca actggaaaac tctctcctgt caaggaactt tcgttgacca
    21241 tacctaaacc tgaaactact tgtccatcaa acagaatttc atttccttga gataagatca
    21301 agacatctcc tatttgaaca tcggaactct tgatactaac aaccgtatcg ccctgtacta
    21361 ggaatacatc gctctctttt gcaagaagac tctgttctaa atctgttgca gtttttttca
    21421 aggaccactg atctaaatga ttccccaaat caagcataaa catgatattg ctagctgtct
    21481 tggattggtt cataaacaag gacaataaaa tagccgaaca gtccaagact tccatcgtta
    21541 gttccttacg cgctagtgtt tgataggctt ctctaatata acccaaagcc tgataacaag
    21601 tccatatata gcgaatagga tacggcacaa aactacgaaa aagtacacgc ttaaccgctg
    21661 cacctgaaac aatagaataa gcactctctt ctctacgaat gggaagagtc atcaactcag
    21721 aaactttccc tttatcaatt ctttttaaaa aggcttctgc attatctaat acagaaaagc
    21781 cttcttttat gcgtagagta aagtgctgtt gatccatgta aaactggata gactcaatcc
    21841 ccttttcatc tctcgccaag gaacgaagat agtcttgaat atccaaggta agtgaaaaag
    21901 aagatgatag tcggatatgt tggtatcctc tatgtagcac tttaaaagac atattattca
    21961 cctataaggc tatctaattg ctcttctttt ttctcttgct cgtacaaata tttggcatct
    22021 tgcaagacat cgtctccatg ttgcttcaca acagaaacag atgcatctag ctcgtctttc
    22081 aacttgtaag ccttagccaa agctttagaa taaccttttt tagcttcctt acttgctaag
    22141 attttcaaac caagggtacc aaatgcgaca ccacccaaaa ataatgaaga ttttttcgca
    22201 acttttgcaa cggttaatac ttcttttaac atacttattt cctccttatc attattatat
    22261 agcaatttag atataaaagc aatttcattc tataaattgg agaattagtt ttatttctac
    22321 tgaatctccc atctacttat tcctaaagtt gctttcattt gcctcttttg atacacttaa
    22381 actatgaata caaatctcaa gcccaaactt cagcgttttg cttctgcgac tgcctttgcc
    22441 tgtcctatct gtcaagaaaa tctgactctg ttagagacta atttcaagtg ctgcaaccgt
    22501 cattcttttg acttggcgaa atttggctat gtcaatctag cacctcaaat caagcaatct
    22561 gctaactatg acaaggaaaa ttttcaaaac cgtcaacaaa tcctagaagc cggcttttac
    22621 caagctatct tagatgctgt atctgacttg cttgcaagct caaaaactac cacaacaatt
    22681 ttggatatcg gttgtggtga aggattctat tctcgcaaac tacaagaaag tcactctgaa
    22741 aaaactttct atgcctttga catctccaaa gattcagtcc aaatcgctgc taaaagtgaa
    22801 cccaactggg cagtcaattg gttcgttggc gacttggcac gacttcctat aaaagacgct
    22861 aacatggata ttctgcttga tatcttctca cctgccaact atggagaatt tcgtcgcgtt
    22921 ttatccaaag acggtatctt gataaaggtt atcccaactg aaaatcacct caaagaaatc
    22981 cgtcaaagag tacaggacca gctgacaaac aaggagtatt ctaaccaaga tatcaaggag
    23041 catttccagg aacactttac catcctatct agtcaaactg cctctctgac taagactatc
    23101 acagcagaac aactccaagc cctactcagt atgactcctc tcctctttca cgttgaccag
    23161 agcaagattg actggagcca actgacagag attaccatcg aagcagagat tttggttggg
    23221 aaagcattct aaactagact tcccaaaggt ataaaactta ccgaaaatct tcaatattat
    23281 aaaaacgcat aagaacaggt acacaaacct taatcttatg cgttttgtta tagtttccat
    23341 acacattaag gggaaatagt tgaaatcagt tctcttaata accattgaat accatatact
    23401 acatttaccc caaatatgat ataggccgta taaatcaagt atttcgattt ttcccgcctc
    23461 aaagaataga tcttatacaa aataaataaa tttaaaataa taaataatag agacaaaatc
    23521 ttcctccaaa atcaatatta aaagtagcca gtcaatcata gttctaatct ttattttcga
    23581 ttcgaaatta caaacttatc aatgaacaat aagtgatata aggccagtac cagaccccaa
    23641 acgctaccac gaaaagagaa ttcttgatga ttgagagtaa acaaatcatg gttaccaata
    23701 tagaggcagg tcaaaataac aaataaaatc caaaataaat ccgtccattt atattttgaa
    23761 aaatattttt ttgactataa taacagtata tgataaaatg taagcagata caaataaaaa
    23821 ggagaaaagc tcatgaacaa attaatgaaa tttatttcgg tttttttgac gtcaattgtg
    23881 ttaattgtat cagcgattcc aagtgtttca gctgtatacg cttctgaaca agtatcacaa
    23941 attgaaacaa atatggaact tcaacctgtc acttctctaa cagaagaaca aatcaataca
    24001 cttgcaaacg aaatccaatc ttttcatcca gacgtctcac aacaatggat caaagaagta
    24061 attaaccgac aattacaagg cgattataca atcccaccta catactctcc atttagagca
    24121 gcttggcaag gtattacagt taatcaaatg ggtgctctat tagatactgc aatagcttta
    24181 gcattaggag gaactactgc aggccttgca aatctaatta aagtaaaagg aaaacatgca
    24241 gcaaaaagtg ctattcgttc agcaatttct agatatctag gtagttggtt tgtaaatgat
    24301 gttgctttag aattcgctat gaatttatta tcaccgggga cttatttagc acaattatgg
    24361 gataaaaatg atgccattcc taacaacgga aggattaact tttaatcatg agatatacaa
    24421 taaaattaat tgggtataac gtattttcgt tgtttatatt ctttatctta tcaatgttgt
    24481 ttaaagttcc ctttaggtgg tggatcagca ttgcaatgac gacttcgtcg tacattgtat
    24541 ataattactt aaagaaaaag agagaaaagg aatgatctta taccagatca ttccttttct
    24601 gctttctgta aatccctcgg agtgtgtttg gcgctttgat acgaagtgtc aaagctgtat
    24661 aaacgttact atttccaaaa aagtaacaga aaattcctgc tttgtaggac tgctttgggt
    24721 gagtaataga catgtcgact caccctatct cctgatggcg aaaagaattt agcaatggtg
    24781 caagttgttc tgaactcgag aaaaaacatg ccgaaatcga agaaaagcgt gcagaacttg
    24841 aagcgaagaa gcaagaaatg ttgaatcgct tggataaata gaatttagaa aacagaaaaa
    24901 ctaaaaagaa tgtagggttt atttccctac attcttaaaa taacttagta cataaatgac
    24961 aatgctgcca ctgccgtcaa tattgcaaaa actattttcc aaattttttt attttttcca
    25021 aaaatcttat caggtaacaa gcttattaca agaaaggtaa taaacaacac caatttaagt
    25081 gtgtatatca taaaaacacc ttctttccta caattatatt ataatacttt atgtaagcga
    25141 atacaagaga tgtgaggtaa ccaactacga aaaaatataa ggctgaagac agtaaaaacc
    25201 agcatttaaa gccttcactg tatctaggat ttccctattt ttagacaaga ttgacccaaa
    25261 tccacagcat ttaaaaaagc gaatttcaat cgaaactcgc ttttttacaa aatgtattag
    25321 tataaatttg tatcttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
    25381 gttgctcaaa gcaccgcttt gaggttgcag ataaagctga cgtggtttga agagattttc
    25441 gaagagtatt agttcaagtg ccagatgtct tcattatact gagcgattgt acggtcagat
    25501 gagaagaatc ctgctttaga aatgttaacg atgactttat ccaaccatgc gtcacggtct
    25561 tcgtagtcag caagcatttg ctctttgact ttgatgtagt cttccaagtc aagaagagtc
    25621 atgaaccagt ctttgttgat caattcattg taaagacgtt ccaagcgctc tttgtttcca
    25681 gctgcaagaa ctgcatcact aacgatgaag tcaaccaatg gtttgatagc ttcacgagcg
    25741 tagaattcgc ttgatttgta agctgctttt gcgtaaaggt cgataacagt ttctgaatct
    25801 tcaccgaaga tgtagatgtt ttcttctcca accaactcag cgatttccac gttagcaccg
    25861 tccatagtac caagtgtcaa agctccgttc aacatgaatt tcatgttacc agtacctgaa
    25921 gcttctttag aagcaagtga aatttgttct gagatatcac atgctgggat aaggaaactt
    25981 gctgcagtaa cgttgtagtt ttcaaccata actacttgca agtgtggagc tactgctgga
    26041 tcgttagcaa taacttctga catgcaaagg attaaatgga taatgtcttg agcgattgtg
    26101 taggctggag ctgctttacc accaaagaag attgtgattg gacgagcagg gatgttacca
    26161 gctttgatgt caaggtattt gtggatcacg tacaaagcgt tcatttgttg gcgtttgtac
    26221 tcgtgaagac gtttgatttg gatatcaaag atagaatttg aattgatttc cacaccttgg
    26281 tgttctttca agtgacgagc caatttacgt ttgttgtgag ccttgatgct ttccaatttt
    26341 tctttgacag ctgctttgtc ttcataagac aaaagttttt caagctcatc tgcttcatgg
    26401 tgccaaccat ctccaagaat ctcatctaag tagtgagaca atcttgggtt agcatgcata
    26461 agccaacgac ggaaagtgat accgtttgtt ttgttgttga acttttctgg gtaaaggtcg
    26521 tagaaggctt tcaactcaga atttttcaag atttcagtat ggagtgctgc aaccccgtta
    26581 acactgtatc cgtagtggat atccatgtga gccatgtgaa cacgtccgct ctcatcgatg
    26641 atttgaacag ctggatcttt gtactctgcc ttcacacgac ggtccaattc ttcgatgatt
    26701 ggtaccaagt gaggaaccac ttcttgcaag aattcaagag gccatttttc aagcgcttca
    26761 gcaaggattg tgtggttagt gtaggcagtc atgctacgaa caattgagat tgcttcgtca
    26821 agctcgatac cacgtgcagt taaaagacga atcaattcag gaatcaccat tgatgggtga
    26881 gtatcgttga tttggacaac tgcgtagtca gcaaggtcat gcaagttgct tcctttttcg
    26941 attgcttcgt cgatgatcaa ttgcgcaccg tttgaaacca tgaagtattg ttggaagata
    27001 cggagcaatt caccttgacg gtcactatca tctgggtaaa ggaagagagt caagttgcga
    27061 gcgatatctg tcttgtcaaa gttgatacca tctttaataa tagaagaatc aactgaatcc
    27121 aagtcaaaca aacgcaagcg gtttttagtc gctgtttcat aaccagtaac atcaatatcg
    27181 taaagagttg atgtcaaagt aaagtctgca aatggtactt ggtagctacg gcttgagcaa
    27241 accaaccagt tttgctctgt caaccatgca tttggaattg tttcttgttg gttgttttta
    27301 agaacttgtt ggaaaagacc aaagtggtag ttaagaccaa caccgtcacc attcaaacca
    27361 agagtagcaa ttgagtcgat aaagcaggca gccaaacgtc ccaaaccacc attaccaaga
    27421 gatggttcca attcaacttc ttcaacttcg atcaagtctt tacctgcagc tgcaagttct
    27481 tttttaacat cgtcgtaaag accaaggtta atcaagttgt ttgacaagag tttaccaatc
    27541 aagaactcag ctgagatgta gtaaactttt ttcttaccag tgttgactgg tttttggctg
    27601 cttgcaagct tgctgtagtt aagaagagca aggtaaagct cttcattgct acattctgca
    27661 atggttttat tgtaacgatt ttgtacaaat tcttgtagtg ataacatgtt tagttgtctc
    27721 ctgattattg tcttatttct ttaaatctac caaattttca ttaattcggc gataaattgt
    27781 tgtcaagtca agcaaacctt cctcgacagc tggtgtcaat tgatcttcag tcatacgcca
    27841 agaccagttt ccaccaaggg tagatgggaa gttcatacga gctgcctcat ccaattctag
    27901 taaatcttgc atagtcgcaa ttgccataaa gctaactgat gaaaatactg tacgaagcat
    27961 agcgtgtacc actgtttcgt attctttacg gttcgtgtaa cgagccatgt actcacgagt
    28021 cgcatcatca atctcattac ggtaccaacc aagaaccgta ttgttatcgt gtgttcctgt
    28081 gtacataact gagttagcag gtgccaagtg tgggctatca atgctttcgt cttctgggtt
    28141 gaaggcaaat tgaagaatct tcattcctgg gaagccagta cgttcacgca attcgatcac
    28201 ttcatctgtc atgaagccaa ggtcttctgc gatgatgttt agctcaccaa gttcttcctt
    28261 aacggctgca aaaagcttgt agcctggacc tttcacccac tcaccaggtg ctgctgtatc
    28321 ggaaccagca gggatttccc aataagattc gaagccacgg aagtggtcga tacgaacgat
    28381 atcgtagatt ttgaagcttt cacgcaagcg ttcaatccac catttgtagc cgtctttgtc
    28441 cattgcttcc cagtcataga ttgggttacc ccaaagctga ccagttacag aaaactcatc
    28501 tggtggacat cctgcgatac aagtagcctt accattgaca tctgttttga agagatgtgg
    28561 atttgcccac atatcacttg aatcttccgc tacgtagatt ggcatgtccc caacgatttc
    28621 gatgtggttg tcgttagcgt aagctttcaa tttcaaccat tgttggaaga agaagtattg
    28681 agtcacacgg tggtaaacca acttgtctgc caattgctca cgatagcttt caagtgctga
    28741 agctttacga gcacgagcat ctgcatctgg ccattcagtc caagcaagat tgtcaaaatg
    28801 ctctttgata gccatatact cagcaaagag ctcaagccat gattggttgt cttgagcaaa
    28861 tttctcaaaa tctttaacat atccgacttc aaagaaacgc ttcaccgctt tttctaaaag
    28921 aggacgacgt gcatagtaga ttttagcata gtcaacttca gacgcatcgc taccaaagtc
    28981 aactccttca aggtcacttg cttccaacaa accttgctcc accaagatat ctaaatcgat
    29041 aaaatgagtg tttcctgcga aggctgagaa agattggtaa ggagaatccc cgtaactagt
    29101 tgctcctaat ggaaggattt gccagtaacg ttgttttgta cggaccaaga aatcaacgaa
    29161 gtcgtaagca ctttgaccaa atgatccgat tccgtaagct cctggaagag aagagatgtg
    29221 catcaacaca ccactttgac gttttttcat aatagcacct cgtgtgttaa aataatggaa
    29281 cgttgcgtat ttttcagacg caaacgtttg cgttacttat aagtatactc cttttcaagc
    29341 ataattgcaa gcgtttttaa aaaacttttt tgattatttt taaggagact aactcatttt
    29401 agcaaagata acttaaaact atctaatcct aaggtttgac tctcacgaga cagtatacaa
    29461 agtacaaaac ctccttaggg agcttgaatt tatatgcaac aaagcacaaa cgtctataga
    29521 aaatagatat agattagaaa tagggaggta gcccctcctg atttccctct ttagacagat
    29581 tccatatatt tttattaaaa atactgtatt cttatctatt tcatactttt cttctattaa
    29641 aatgcaaaat tatgctatca aatcaagctt aaaaattttt taaaattttt acaaaaaata
    29701 cttgcaaccg ttttctattt atgctatact aagctcataa aggaaaacgt ttgcgtttcc
    29761 ttatcaataa aacttgctat tctttgggag gaatacacta tgtcatctaa atttatgaag
    29821 agcactgcgg tgcttggaac tgttacactt gctagcttgc tcttggtagc ttgcggaagc
    29881 aaaactgctg ataagcctgc tgattctggt tcatctgaag tcaaagaact cactgtatat
    29941 gtagacgagg gatataagag ctatattgaa gaggttgcta aagcttatga aaaagaagct
    30001 ggagtaaaaa tcactcttaa aactggtgat gctctaggag gtcttgataa actttctctt
    30061 gacaaccaat ctggtaatgt ccctgatgtt atgatggctc catacgaccg tgtaggtagc
    30121 cttggttctg acggacaact ttcagaagtg aaattgagcg atggtgctaa aacagacgac
    30181 acaactaaat ctcttgtaac agctgctaat ggtaaagttt acggtgctcc tgccgttatc
    30241 gagtcacttg ttatgtacta caacaaagac ttggtgaaag atgctccaaa aacatttgct
    30301 gacttggaaa accttgctaa agatagcaaa tacgcattcg ctggtgaaga tggtaaaact
    30361 actgccttcc tagctgactg gacaaacttc tactatacat atggacttct tgccggtaac
    30421 ggtgcttacg tctttggcca aaacggtaaa gacgctaaag acatcggtct tgcaaacgac
    30481 ggttctatcg caggtatcaa ctacgctaaa tcttggtacg aaaaatggcc taaaggtatg
    30541 caagatacag aaggtgctgg aaacttaatc caaactcaat tccaagaagg taaaacagct
    30601 gctatcatcg acggaccttg gaaagctcaa gcctttaaag atgctaaagt aaactacgga
    30661 gttgcaacta tcccaactct tccaaatgga aaagaatatg ctgcattcgg tggtggtaaa
    30721 gcttgggtca ttcctcaagc cgttaagaac cttgaagctt ctcaaaaatt tgtagacttc
    30781 cttgttgcaa ctgaacaaca aaaagtatta tatgataaga ctaacgaaat cccagctaat
    30841 actgaggctc gttcatacgc tgaaggtaaa aacgatgagt tgacaacagc tgttatcaaa
    30901 cagttcaaga acactcaacc actgccaaac atctctcaaa tgtctgcagt ttgggatcca
    30961 gcgaaaaata tgctctttga tgctgtaagt ggtcaaaaag atgctaaaac agctgctaac
    31021 gatgctgtaa cattgatcaa agaaacaatc aaacaaaaat ttggtgaata aaaaatttgt
    31081 tcaagggggg tggaaatcaa atcccccttt gaatttatca atagagacac aaataattta
    31141 gctttcttat aaaaaagtag tatcctatga aaggagttaa tatggaaaag caacaaccta
    31201 gtaaagcagc cctgctgtct atcattcctg ggttaggaca gatttacaat aaacaaaaag
    31261 ccaaaggttt tatcttcctt ggtgtaacca tcgtatttgt cctttacttc ctagcacttg
    31321 caacccctga attgagcaac ctcatcactc ttggtgacaa accaggtcgt gataattccc
    31381 tctttatgct gattcgtggt gccttccatc taatctttgt aatcgtttat gtactctttt
    31441 atttctcaaa tatcaaagat gcacatacga ttgcaaaacg cattaacaat ggaattccag
    31501 ttccacgcac actcaaagac atgatcaaag ggatttatga aaatggcttc ccttacctct
    31561 tgatcattcc atcttatgtt gccatgacct tcgcgattat cttcccagtt atcgtaacct
    31621 tgatgatcgc ctttaccaac tacgacttcc aacacttgcc accaaacaag ttgttggact
    31681 gggttggttt gaccaacttt acaaacattt ggagcttgag taccttccgt tctgcctttg
    31741 gttctgttct ttcttggact atcatttggg ctttggcagc ttctacttta caaatcgtaa
    31801 ttggtatctt cacagctatc attgccaacc aaccatttat caaaggaaaa cgtatctttg
    31861 gtgttatttt ccttcttcct tgggctgtcc cagccttcat cactatcttg acattctcaa
    31921 acatgtttaa cgatagtgtc ggtgctatca acactcaagt attgccaatc ttggctaaat
    31981 tccttccttt ccttgatgga gctcttattc cttggaaaac agacccaact tggactaaga
    32041 ttgccttgat tatgatgcaa ggttggctcg gattcccata catctacgtt ttgactttgg
    32101 gtatcttgca atctattcct aacgaccttt acgaagcagc ttatattgac ggtgccaacg
    32161 cttggcaaaa attccgcaac atcactttcc caatgatttt ggctgttgcg gcacctactt
    32221 tgattagcca atacaccttc aactttaaca acttctctat catgtacctc ttcaatggtg
    32281 gaggacctgg tagtgtcgga ggtggagctg gttcaaccga tatcttgatc tcatggatct
    32341 accgtttgac aacaggtaca tctcctcaat actcaatggc ggcagctgtt accttgatta
    32401 tctctatcat tgtcatctca atctctatga tcgcattcaa gaaactacac gcatttgata
    32461 tggaggacgt ctaagatgaa taactcaatt aaactcaaac gtagactgac tcaaagcctt
    32521 acttaccttt acctgattgg tctatcaatt gtaattatct atccactgtt gattaccatt
    32581 atgtcagcct ttaaagcagg taacgtctca gcctttaaac tagatactaa tatcgacctc
    32641 aattttgata actttaaagg cctcttcact gaaaccttgt acggtacttg gtacctcaac
    32701 actttgatta tcgccttaat taccatggct gttcaaacaa gtatcatcgt acttgctggt
    32761 tatgcttaca gccgttacaa cttcttggct cgtaaacaaa gtttggtctt cttcttgatc
    32821 atccaaatgg tgccaactat ggccgctttg acagccttct tcgttatggc gcttatgttg
    32881 aacgccctta accacaactg gttcctcatc ttcctctacg ttggtggtgg tatcccgatg
    32941 aatgcttggc tcatgaaagg ctacttcgat acagtgccaa tgtctttaga cgaatctgca
    33001 aaactagacg gtgcaggaca cttccgccgc ttctggcaaa ttgttctacc acttgttcgc
    33061 ccaatggttg ccgtacaagc tctctgggcc ttcatgggac ctttcgggga ctacatcctc
    33121 tctagtttct tgcttcgtga gaaagaatac tttactgttg ccgtaggtct ccaaaccttc
    33181 gttaacaatg cgaaaaactt gaagattgcc tacttctcag caggtgctat cctcatcgcc
    33241 cttccaatct gtattctctt cttcttccta caaaagaact ttgtttcagg acttacaagt
    33301 ggtggcgaca agggataatt tatccccgcc accctttttc attttatact cttcgaaaat
    33361 ctcttcaaac cacgtcagct ttatctccaa cctcaaagtt gtgctttgag caacctgtgg
    33421 ctagtttgca ctttgatttt cattgattat tagcaattgt cactgtaaat aatatccttg
    33481 tagcaagcaa tttttctcct agacttgaaa taaagcgcat ttctctatat aataatactc
    33541 atatagaaaa caccttttag aaagatacct atgcttccat atccattttc ctatttttca
    33601 agtatttggg ggtttcgtaa gcccctgtcc aaacgtttcg agctcaactg gtttcaactt
    33661 ctctttacca gtatcttcct tatcagcttg tctatggtac ccattgctat ccaaaacagc
    33721 tcccaggaga cctatccgct agaaactttt atcgataatg tctatgaacc tctgacaaat
    33781 gaggttgtcc aggatctctc tgaacatgct acaattgtcg atggcacatt aacttatact
    33841 ggaacagcta gtcaaacccc ttctgttgtg attggtccaa gtcaaatcaa ggaattacct
    33901 aaggacttgc aactgcattt cgatacaaat gagctagtca tcagcaagga aagcaaggag
    33961 ctgacccgca tctcttaccg agccattcag actgagagtt tcaaaagcaa agacagcttg
    34021 acccaagcaa tttctaaaga ctggtaccaa caaaatcgtg tctatatcag cctcttccta
    34081 gttctcggtg cgagcttcct ctttggtttg aatttcttta tcgtctctct aggagctagt
    34141 cttctccttt atatcactaa gaaatcacgc ctcttttcat ttagaacctt taaagagtgc
    34201 tatcacttta tcttgaactg tttaggattg ccgactctga ttacacttat tttgggatta
    34261 tttggccaaa atatgacaac cctgattact gtacaaaata ttctttttgt tctgtatctg
    34321 gtcactatct tttataaaac acatttccgt gatccaaatt accataaata ggagattttt
    34381 atgcccgtta cgattaaaga cgtggccaag gctgctggtg tttcgccttc aaccgtaacc
    34441 cgtgttattc aaaataaatc aaccattagc gacgaaacaa aaaaacgcgt tcgcaaagct
    34501 atgaaggaac tcaactacca cccaaacctc aacgctcgta gcttggtaag cagctatact
    34561 caggttatcg gattagttct tcctgatgac tcagacgcct tctaccagaa tcctttcttt
    34621 ccatcggttc tacgtggcat ctctcaagtc gcatctgaaa accactatgc cattcagata
    34681 gcaacaggga aagatgagaa ggagcgtctc aacgctattt cacaaatggt ctacggcaag
    34741 cgtgtagatg ggctaatctt tctctatgcc caagaagaag accctctcgt aaaactcgtc
    34801 gcagaagaac agttcccctt ccttatctta ggtaaatctc tatctccttt catcccactt
    34861 gtcgacaacg gcaatgttca agctggtttt gatgcgactg aatatttcat caaaaaaggc
    34921 tgcaaacgca ttgcctttat cggaggaagt aaaaagctct tcgtgaccaa agaccgttta
    34981 acaggctatg aacaggcgct taaacattac aaacttacca ctgacaacaa tcgcatctac
    35041 tttgccgacg agtttctgga agaaaagggc tataaattta gcaagcgatt attcaagcac
    35101 gatccacaaa ttgatgctat catcacaacc gatagcctcc tagctgaagg tgtttgtaac
    35161 tatattgcca aacaccagct ggatgtccct gttctcagct ttgactcggt taatcccaag
    35221 ctcaacttgg cagcctatgt cgatatcaat agtttagagc ttggtcgtgt ttcccttgaa
    35281 actattctcc agattattaa tgataataaa aacaataaac aaatttgtta ccgtcaattg
    35341 atcgcccaca aaattatcga aaaataagag actgggcaaa gagtcgttaa aagcaaaaac
    35401 gcatactatc aggtattgaa aaaacttgat actatgcgtt tta
//
LOCUS       DAVBOH010000019        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOH010000019 DAVBOH010000000
VERSION     DAVBOH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.019"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ873_001008"
     CDS             complement(21..833)
                     /locus_tag="VQ873_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3107284.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ873_001009"
     CDS             1023..2441
                     /locus_tag="VQ873_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3107285.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ873_001010"
     CDS             2494..3201
                     /locus_tag="VQ873_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107286.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ873_001011"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ873_001011"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3107287.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ873_001012"
     CDS             4279..5601
                     /locus_tag="VQ873_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3107288.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ873_001013"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ873_001013"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3107289.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ873_001014"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ873_001014"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3107290.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ873_001015"
     CDS             complement(7036..7353)
                     /locus_tag="VQ873_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3107291.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ873_001016"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ873_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3107292.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ873_001017"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ873_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3107293.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ873_001018"
     CDS             complement(8829..9251)
                     /locus_tag="VQ873_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3107294.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ873_001019"
     CDS             9398..9574
                     /locus_tag="VQ873_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107295.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ873_001020"
     CDS             9976..12189
                     /locus_tag="VQ873_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3107296.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ873_001021"
     CDS             complement(12411..12887)
                     /locus_tag="VQ873_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3107297.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ873_001022"
     CDS             13110..16313
                     /locus_tag="VQ873_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3107298.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ873_001023"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ873_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ873_001024"
     CDS             complement(17456..18085)
                     /locus_tag="VQ873_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3107299.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ873_001025"
     CDS             complement(18095..19096)
                     /locus_tag="VQ873_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3107300.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ873_001026"
     CDS             complement(19127..19768)
                     /locus_tag="VQ873_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3107301.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ873_001027"
     CDS             complement(19787..20602)
                     /locus_tag="VQ873_001027"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3107302.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ873_001028"
     CDS             20873..21307
                     /locus_tag="VQ873_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107303.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ873_001029"
     CDS             21319..22509
                     /locus_tag="VQ873_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3107304.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ873_001030"
     CDS             22520..23011
                     /locus_tag="VQ873_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3107305.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ873_001031"
     CDS             23026..23805
                     /locus_tag="VQ873_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3107306.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ873_001032"
     CDS             23792..24610
                     /locus_tag="VQ873_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3107307.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ873_001033"
     CDS             24610..24903
                     /locus_tag="VQ873_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3107308.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ873_001034"
     CDS             24925..26826
                     /locus_tag="VQ873_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3107309.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ873_001035"
     CDS             26886..27887
                     /locus_tag="VQ873_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3107310.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ873_001036"
     CDS             complement(27997..28332)
                     /locus_tag="VQ873_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107311.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ873_001037"
     CDS             complement(28343..28585)
                     /locus_tag="VQ873_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107312.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ873_001038"
     CDS             complement(28596..29138)
                     /locus_tag="VQ873_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3107313.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ873_001039"
     CDS             complement(29154..29348)
                     /locus_tag="VQ873_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107314.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ873_001040"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ873_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3107315.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ873_001041"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ873_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3107316.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ873_001042"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ873_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3107317.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ873_001043"
     CDS             33051..34031
                     /locus_tag="VQ873_001043"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3107318.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOH010000020        34102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOH010000020 DAVBOH010000000
VERSION     DAVBOH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.020"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ873_001044"
     CDS             85..366
                     /locus_tag="VQ873_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3107319.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ873_001045"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ873_001045"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3107320.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1601..2937)
                     /locus_tag="VQ873_001046"
                     /pseudo
     CDS             complement(1601..2937)
                     /locus_tag="VQ873_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819742.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ873_001047"
     CDS             3042..3782
                     /locus_tag="VQ873_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3107321.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ873_001048"
     CDS             complement(3811..4266)
                     /locus_tag="VQ873_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3107322.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ873_001049"
     CDS             complement(4286..5461)
                     /locus_tag="VQ873_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3107323.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ873_001050"
     CDS             complement(5520..6365)
                     /locus_tag="VQ873_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3107324.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ873_001051"
     CDS             6490..7047
                     /locus_tag="VQ873_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3107325.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ873_001052"
     CDS             7066..7533
                     /locus_tag="VQ873_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3107326.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ873_001053"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ873_001053"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3107327.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ873_001054"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ873_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3107328.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ873_001055"
     CDS             9094..9342
                     /locus_tag="VQ873_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3107329.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ873_001056"
     CDS             9443..10603
                     /locus_tag="VQ873_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3107330.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
     gene            10871..11740
                     /locus_tag="VQ873_001057"
     CDS             10871..11740
                     /locus_tag="VQ873_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3107331.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11744..12700
                     /locus_tag="VQ873_001058"
     CDS             11744..12700
                     /locus_tag="VQ873_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3107332.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12700..13464
                     /locus_tag="VQ873_001059"
     CDS             12700..13464
                     /locus_tag="VQ873_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107333.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13464..14174
                     /locus_tag="VQ873_001060"
     CDS             13464..14174
                     /locus_tag="VQ873_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107334.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14482..15138
                     /locus_tag="VQ873_001061"
     CDS             14482..15138
                     /locus_tag="VQ873_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3107335.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15246..16341
                     /gene="prfB"
                     /locus_tag="VQ873_001062"
     CDS             join(15246..15317,15319..16341)
                     /gene="prfB"
                     /locus_tag="VQ873_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3107336.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ873_001063"
     CDS             16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ873_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3107337.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17044..17970
                     /locus_tag="VQ873_001064"
     CDS             17044..17970
                     /locus_tag="VQ873_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107338.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18256..20436
                     /locus_tag="VQ873_001065"
     CDS             18256..20436
                     /locus_tag="VQ873_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3107339.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20488..21303
                     /locus_tag="VQ873_001066"
     CDS             20488..21303
                     /locus_tag="VQ873_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3107340.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21443..22786
                     /locus_tag="VQ873_001067"
     CDS             21443..22786
                     /locus_tag="VQ873_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3107341.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VQ873_001068"
     CDS             23163..24353
                     /locus_tag="VQ873_001068"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3107342.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VQ873_001069"
     CDS             24906..25841
                     /locus_tag="VQ873_001069"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3107343.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VQ873_001070"
     CDS             25875..26912
                     /locus_tag="VQ873_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3107344.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VQ873_001071"
     CDS             27085..27690
                     /locus_tag="VQ873_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3107345.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VQ873_001072"
     CDS             27846..28376
                     /locus_tag="VQ873_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3107346.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ873_001073"
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ873_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3107347.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            29482..29964
                     /locus_tag="VQ873_001074"
     CDS             29482..29964
                     /locus_tag="VQ873_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3107348.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VQ873_001075"
     CDS             29966..31507
                     /locus_tag="VQ873_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3107349.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VQ873_001076"
     CDS             complement(31563..32366)
                     /locus_tag="VQ873_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3107350.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32670)
                     /locus_tag="VQ873_001077"
     CDS             complement(32449..32670)
                     /locus_tag="VQ873_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107351.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33149..33358)
                     /locus_tag="VQ873_001078"
     CDS             complement(33149..33358)
                     /locus_tag="VQ873_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107352.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ873_001079"
     CDS             33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ873_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3107353.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33820..34059
                     /locus_tag="VQ873_001080"
     CDS             33820..34059
                     /locus_tag="VQ873_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3107354.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        10382 a         6356 c         7395 g         9969 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttactccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggtaatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaactgcgt caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac
    10741 aacctcaaag cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    10801 cattgagtat aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag
    10861 agtgaatctt atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct
    10921 gttagcccta ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg
    10981 tgatatttat atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa
    11041 tttctttgta gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga
    11101 gtttcttgct taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat
    11161 tggggtttct ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc
    11221 cttccctcaa gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt
    11281 gcagttaatg attttgggca tttccttgat tttgatgatt ttgttacaag tcattgtcca
    11341 aaagactaag atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt
    11401 gatggggatc aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc
    11461 gggtgcggct ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt
    11521 tactccaggt cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg
    11581 tgcggctctt ggtggctttg tgattggtct attggaaacc tttgcgactg cctttgggat
    11641 gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc
    11701 agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa
    11761 agttaatatt ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt
    11821 ttcagtcgga gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat
    11881 tattttggct gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca
    11941 tgctggtttc atggcgattg gtgcctatgc agcagctatt attggttcta aatcaccaac
    12001 ctacggtgcc ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt
    12061 acttgtcggc attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg
    12121 tgtttctgaa attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc
    12181 aggtatttta gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat
    12241 tacaaccatt gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt
    12301 tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat
    12361 cgcttttgtc tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat
    12421 cgggtctgtt gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt
    12481 tgtatttggt ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat
    12541 tttaaatatg cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt
    12601 ggtattggta atgattttca gaccaggtgg actccttgga acgtgggaac tgagcctatc
    12661 acgtttcttt aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa
    12721 cagttaacca aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac
    12781 gaaggggaac tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac
    12841 cttttgaccg gtgtttatga accaagcgag ggaacagtaa ccctagatgg tcaccttttg
    12901 aatgggaaat caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc
    12961 cgtctcttta aagatttaac agttttagat aatgttttga ttgcttttgg aaaccatcac
    13021 aaacagcatg tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa
    13081 ttaaaggcta aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact
    13141 cttgctaaaa atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct
    13201 acggaaccta aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca
    13261 gccgaattga ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg
    13321 attgaacacg atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat
    13381 ggccgtttaa ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa
    13441 gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt
    13501 acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt
    13561 cccttatcgg tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg
    13621 ttcgaccaag ttcaggaaag attgaatttt taggtcaaga aatccaaaaa atgccagctc
    13681 agaaaatcgt ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct
    13741 tgactgttat ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc
    13801 aagcaaactt gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgt aagaaccaag
    13861 atgcagctac tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt
    13921 caacaccaaa acttcttctt ttagatgaac catcaatggg acttgcccca atcttcatcc
    13981 aagagatttt tgatatcatt caagatattc agaagcaaga aacaaccgtc ctcttgattg
    14041 aacaaaatgc caataaagca ctcgcaatct ctgaccgagg atatgtattg gaaacaggaa
    14101 aaatcgtcct atcagggaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat
    14161 atctaggtgg ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt
    14221 aatcatcaat atagtccggg ggaccttttt agtcggtaga ttgagattgc aaacaaatat
    14281 gcatctacat tgaaagctta atttctaata attgaaaaaa tcgaatgaaa aatttcttac
    14341 cttcattcac agagctctat ttcagagctc tttttgctag cttattcata cttttctgaa
    14401 tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa
    14461 gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat
    14521 attagtccag atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac
    14581 cgtctgcctg ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca
    14641 caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat
    14701 aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt
    14761 ctagaagatg caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat
    14821 aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt
    14881 gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt
    14941 cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat
    15001 attccgcgta aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta
    15061 ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact
    15121 tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt
    15181 agagcaaaag atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag
    15241 tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt
    15301 ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac
    15361 aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa
    15421 ttgaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa
    15481 gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg
    15541 cagttagccg aacttgataa gataatgacc agctacgaga tgactctact attgtcagaa
    15601 ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg
    15661 caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt
    15721 aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta
    15781 tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcatcgctta
    15841 gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa
    15901 gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg
    15961 gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta
    16021 cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat
    16081 ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagat
    16141 aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc
    16201 caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt
    16261 gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat cgatgcttat
    16321 ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag
    16381 atgtcgttaa aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc
    16441 aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc
    16501 gttctctgta tcgtgaagta aaaatcgata aaggaagtct atcagttgct ggttttaatc
    16561 tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc
    16621 aagattataa attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag
    16681 taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg
    16741 gattgaagca taaggttcgt tctttcccaa atgaactctc aggtggggag cagcagcgaa
    16801 ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag
    16861 gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg attaacctac
    16921 aagggacaac tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc
    16981 gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat
    17041 acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat
    17101 ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata
    17161 tttgcatctg ttattttcaa tacagcgaaa ttagctacag atattgaaaa taatgtccgt
    17221 gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt
    17281 caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg
    17341 gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg
    17401 ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta
    17461 gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt
    17521 gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt
    17581 atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt
    17641 tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg
    17701 gttggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt
    17761 ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa
    17821 tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt
    17881 ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga
    17941 atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg aggagattgt
    18001 aaaatctcct tttttgctac aagagttttt gaaaagagat gcgtagaaga aaagagcttc
    18061 caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac
    18121 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
    18181 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
    18241 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
    18301 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
    18361 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
    18421 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
    18481 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
    18541 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
    18601 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
    18661 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
    18721 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
    18781 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
    18841 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
    18901 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
    18961 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
    19021 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
    19081 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
    19141 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
    19201 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
    19261 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
    19321 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
    19381 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
    19441 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
    19501 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
    19561 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
    19621 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
    19681 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
    19741 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
    19801 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
    19861 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
    19921 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
    19981 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
    20041 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
    20101 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
    20161 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
    20221 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
    20281 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
    20341 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
    20401 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
    20461 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
    20521 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
    20581 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
    20641 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
    20701 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
    20761 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
    20821 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
    20881 gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
    20941 tggtgggata aaggttttca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
    21001 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
    21061 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
    21121 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
    21181 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
    21241 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa
    21301 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
    21361 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
    21421 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
    21481 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc
    21541 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
    21601 tactttcttg ttaccgattt ttcagcaatt agatgaagct agcgatagtg tacaagcagt
    21661 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
    21721 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
    21781 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
    21841 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
    21901 tgaagcagat atgaccttgg atatgggatt cttggaaact gttgataaga ttgctgacag
    21961 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
    22021 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat
    22081 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
    22141 ttaccagttg actcagtcga tgcagccgta tttggcaatg atttttgtta acactaaaac
    22201 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
    22261 tggcgatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
    22321 tgagtatatt gtcgcaacag atttggcagc acgtgggatt gacattgaag gtgtcagcca
    22381 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
    22441 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
    22501 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga
    22561 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
    22621 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
    22681 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg
    22741 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
    22801 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
    22861 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
    22921 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
    22981 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
    23041 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
    23101 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca tgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataaggc aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcatggg gatatttcaa gccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagatca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gatcaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatca aaaaatctga
    25861 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg acacatcaaa ccatgcagga
    28441 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    28681 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    28981 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tacattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtgg aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaatcgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aagggggcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgctctt taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccaga tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaata tcctcaatgt cttcttgttt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaacac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gggaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atggaaatgg ctgaagacgg
    30301 tgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat cttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caaaccaaga acttgcaaat
    30961 tggttacgac cttcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagctttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaaa gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc cagtaaatgg
    32521 tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga aatttagagg
    32581 aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg tgatagcaat
    32641 gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct tcttctgaaa
    32701 aatgctcatg aagggcttga tccaggtcgc aagatttcat tttagaaagt ccagtaactc
    32761 ccttcttctt caggatattc tttttcatgg tattatttag atggtcaagt gagtcaaaag
    32821 aagtttcgac aagagcatac cctttttcta tcagagtttt tagatgttta ggggcatcaa
    32881 taccataagt gtactcaaag tattttggaa accagatctt aagaaagctc gtaaagctag
    32941 ccagttctct aaacgctaag aactagctac aacacagcat ttacaacact tcatggttca
    33001 caccatgggg tgctttttaa tgattttaag caaaattcac acttaattga aagttattta
    33061 aattagatga aaatttattt tttgaaaaag cgggaaaaca ttgattctaa gcgaattttg
    33121 aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga
    33181 ttctccatag taaaatgata tctcctgcta gtgaatcatc tactaataag tccatatttc
    33241 gcttgggaac gggcttggga cttagaagcc aagtatccaa ctctcgttca ggcgatatga
    33301 agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg gatagcatct
    33361 ttcaaacatt tatttcctat tctaacaaat ttctaaatac tttaagaaat ttatagtctg
    33421 tcaagttttt ttcttgacac atgccagaaa tctgctataa tagaacatgt gctaaatagc
    33481 tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa
    33541 tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac gtagcagatt
    33601 cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac ccacttgttg
    33661 ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct aatggagctc
    33721 aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa aaattccacg
    33781 attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat tgaaaatctc
    33841 attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat caagattgag
    33901 gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt gggtcgtgta
    33961 atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc tgtcccaact
    34021 gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga cggatgtctc
    34081 gcttttttgt gtggaataga ag
//
LOCUS       DAVBOH010000021        33668 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOH010000021 DAVBOH010000000
VERSION     DAVBOH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.021"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            426..686
                     /locus_tag="VQ873_001081"
     CDS             426..686
                     /locus_tag="VQ873_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107355.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            640..860
                     /locus_tag="VQ873_001082"
                     /pseudo
     CDS             640..860
                     /locus_tag="VQ873_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1179..2108
                     /locus_tag="VQ873_001083"
     CDS             1179..2108
                     /locus_tag="VQ873_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3107356.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            2122..3045
                     /locus_tag="VQ873_001084"
     CDS             2122..3045
                     /locus_tag="VQ873_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3107357.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            3129..4604
                     /locus_tag="VQ873_001085"
     CDS             3129..4604
                     /locus_tag="VQ873_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3107358.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            4876..5862
                     /locus_tag="VQ873_001086"
     CDS             4876..5862
                     /locus_tag="VQ873_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3107359.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            5984..6844
                     /locus_tag="VQ873_001087"
     CDS             5984..6844
                     /locus_tag="VQ873_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3107360.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(7021..8085)
                     /locus_tag="VQ873_001088"
     CDS             complement(7021..8085)
                     /locus_tag="VQ873_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107361.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDKAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(8148..9059)
                     /locus_tag="VQ873_001089"
     CDS             complement(8148..9059)
                     /locus_tag="VQ873_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3107362.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(9052..9645)
                     /locus_tag="VQ873_001090"
     CDS             complement(9052..9645)
                     /locus_tag="VQ873_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3107363.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(9632..9958)
                     /locus_tag="VQ873_001091"
     CDS             complement(9632..9958)
                     /locus_tag="VQ873_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3107364.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(10097..11260)
                     /locus_tag="VQ873_001092"
     CDS             complement(10097..11260)
                     /locus_tag="VQ873_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3107365.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYT
                     AMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSL
                     AGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLS
                     QTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            11318..12457
                     /locus_tag="VQ873_001093"
     CDS             11318..12457
                     /locus_tag="VQ873_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3107366.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            12525..14375
                     /locus_tag="VQ873_001094"
     CDS             12525..14375
                     /locus_tag="VQ873_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3107367.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14554..14652)
                     /locus_tag="VQ873_001095"
                     /pseudo
     CDS             complement(14554..14652)
                     /locus_tag="VQ873_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14678..15310)
                     /locus_tag="VQ873_001096"
     CDS             complement(14678..15310)
                     /locus_tag="VQ873_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3107368.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15332..16204)
                     /gene="sdaAA"
                     /locus_tag="VQ873_001097"
     CDS             complement(15332..16204)
                     /gene="sdaAA"
                     /locus_tag="VQ873_001097"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3107369.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(16213..16884)
                     /gene="sdaAB"
                     /locus_tag="VQ873_001098"
     CDS             complement(16213..16884)
                     /gene="sdaAB"
                     /locus_tag="VQ873_001098"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3107370.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            17126..17698
                     /locus_tag="VQ873_001099"
     CDS             17126..17698
                     /locus_tag="VQ873_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3107371.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(17750..18070)
                     /locus_tag="VQ873_001100"
     CDS             complement(17750..18070)
                     /locus_tag="VQ873_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3107372.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            18495..18779
                     /locus_tag="VQ873_001101"
     CDS             18495..18779
                     /locus_tag="VQ873_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3107373.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            18834..20942
                     /locus_tag="VQ873_001102"
     CDS             18834..20942
                     /locus_tag="VQ873_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3107374.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            20939..21580
                     /locus_tag="VQ873_001103"
     CDS             20939..21580
                     /locus_tag="VQ873_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107375.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            21787..22593
                     /locus_tag="VQ873_001104"
     CDS             21787..22593
                     /locus_tag="VQ873_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3107376.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            22559..23029
                     /locus_tag="VQ873_001105"
     CDS             22559..23029
                     /locus_tag="VQ873_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3107377.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(23319..23639)
                     /locus_tag="VQ873_001106"
     CDS             complement(23319..23639)
                     /locus_tag="VQ873_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3107378.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            24403..24783
                     /locus_tag="VQ873_001107"
     CDS             24403..24783
                     /locus_tag="VQ873_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3107379.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            25157..26215
                     /locus_tag="VQ873_001108"
     CDS             25157..26215
                     /locus_tag="VQ873_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107380.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            26530..27506
                     /locus_tag="VQ873_001109"
                     /pseudo
     CDS             26530..27506
                     /locus_tag="VQ873_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27883..28257
                     /locus_tag="VQ873_001110"
     CDS             27883..28257
                     /locus_tag="VQ873_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3107381.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            28465..29367
                     /locus_tag="VQ873_001111"
     CDS             28465..29367
                     /locus_tag="VQ873_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107382.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            29423..29776
                     /locus_tag="VQ873_001112"
     CDS             29423..29776
                     /locus_tag="VQ873_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3107383.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            29773..30501
                     /locus_tag="VQ873_001113"
     CDS             29773..30501
                     /locus_tag="VQ873_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107384.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            31633..31872
                     /locus_tag="VQ873_001114"
     CDS             31633..31872
                     /locus_tag="VQ873_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107385.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            32422..>33668
                     /locus_tag="VQ873_001115"
     CDS             32422..>33668
                     /locus_tag="VQ873_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3107386.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATG"
BASE COUNT        10567 a         5594 c         6979 g        10528 t
ORIGIN      
        1 agtgtattga atttataaca gtacaccttg gctgctaaaa tatttctata aattaatttg
       61 actttcctga tagagttgtt cacatcttat ttcaaatcac tataaaagct ctataatctc
      121 tttattaaga tttgcccatc agacgaaata taatggattg aaactagaat agtacacatc
      181 tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttcttg
      241 tttcatttta ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt
      301 ttaaaagtgt tttgatagtt tggatttctt ctttagttga tttcatatca ctgttatata
      361 atgctttttg attttagtct agtattagta agcagactca aaccttagaa aatcttttga
      421 gatcattgac aggtgtatcg aatcctacca cagattcagc acgtctggtt ttggcagagg
      481 ctaagaaagc ttttgcagat gatagtttga cagagcaagg tttacgtgat attttgcaaa
      541 cagtcaaaga tgccattgct tccctagagt ccattaagga aagccagtca gcaactaagg
      601 atggaggaca aacagcgggc aaagaaacag caggagaaga tgagtctgca aatcaaactc
      661 aagaaattag ccaaggaatt aagtaaactt cttaaagact caaaccttga aacagtagat
      721 aaggatgtcc ttgaaaactc tcaaaaagaa cttcaaaaag cagttttgtt cttggcagat
      781 gaaaaagctc tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta
      841 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatctctgag
      901 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg
      961 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     1021 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     1081 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     1141 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     1201 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg gacactctgg ttgattctat
     1261 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     1321 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     1381 tatttagttc aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct
     1441 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     1501 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     1561 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     1621 tattggaaag tcttggtctc aaagaagtca atttttacgc tgacctgggc atctggccct
     1681 atctcctact tttcctaggt atttggaaag gctttggata tagcagtgtc atgtactatg
     1741 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     1801 agtggcaacg tattcgcaac gttaccattc ctcagttgac tccgcttgta actgtattga
     1861 ccatccttgc agtcggaaat atcttccgcg cagactttgg tctcttctat caaatcccac
     1921 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtc tttaatggtt
     1981 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     2041 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     2101 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     2161 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     2221 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     2281 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     2341 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     2401 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     2461 cggacaacct ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc
     2521 aacgctggtt tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact
     2581 gtttgggcct tgattgttcc aatgcttctc tcaccattca atatcatctt gatgcgttcc
     2641 ttcttcaaga agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt
     2701 gaggcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     2761 acgcttttga cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     2821 agtgataact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     2881 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     2941 cgtatggcca tggttgtggt agcaaccctt ccaatcgcga ttttgtatcc attcttccaa
     3001 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagcactt gtttccaaac
     3061 ttcccttgcg tgaagttaag atcattacat tgtttataag tttaaaaata aaaaaaggag
     3121 tttttatcat gaaaaactgg aaaaaatatg cttttgcatc tgctagtgta gttgctttgg
     3181 ctgcaggtct tgctgcttgt ggcaacttga caggtaacag caaaaaagct gctgattcag
     3241 gtgacaaacc tgttatcaaa atgtaccaaa tcggtgacaa accagataac ttggatgaat
     3301 tgttagcaaa tgccaacaaa atcatcgaag aaaaagttgg tgctaaattg gatatccaat
     3361 accttggctg gggtgactat ggtaagaaaa tgtcagttat cacatcatct ggtgaaaact
     3421 atgatatcgc ctttgcagat aactatattg taaatgctca aaaaggtgct tatgctgact
     3481 tgacagaatt gtacaaaaaa gaaggtaaag acctttacaa ggcacttgat ccagcttata
     3541 tcaagggtaa tactgtaaat ggtaagattt acgctgtacc agttgcagcc aacgtagcat
     3601 catctcaaaa ctttgccttc aacggaactc tccttgccaa atatggtatc gatatttcag
     3661 gtgttacttc ttacgaaact cttgagccag tcttgaaaca aatcaaagaa aaagctccag
     3721 acgtagtacc atttgctatt ggtaaagttt tcatcccatc tgataacttt gactacccag
     3781 tagcaaacgg tcttccattc gttattgacc ttgaaggcga tactactaaa gttgtaaacc
     3841 gttacgaagt acctcgtttc aaagaacact tgaagactct tcacaaattc tatgaagctg
     3901 gctacattcc aaaagacgtc gcaacaagcg atacttcctt tgaccttcaa caagatactt
     3961 ggttcgttcg tgaagaaaca gtaggaccag ctgactacgg taacagcttg ctttcacgtg
     4021 ttgccaacaa agatatccaa atcaaaccaa ttactaactt catcaagaaa aaccaaacaa
     4081 cacaagttgc taactttgtc atctcaaaca actctaagaa caaagaaaaa tcaatggaaa
     4141 tcttgaacct cttgaatacg aatccagaac tcttgaacgg tcttgtttac ggtccagaag
     4201 gcaagaactg ggaaaaaatt gaaggtaaag aaaaccgtgt tcgcgttctt gatggctaca
     4261 aaggaaacac tcacatgggt ggatggaaca ctggtaacaa ctggatcctt tacatcaacg
     4321 aaaacgttac agaccaacaa atcgaaaatt ctaagaaaga attggcagaa gctaaagaat
     4381 ctccagcgct tggatttatc ttcaatactg acaatgtgaa atctgaaatc tcagctattg
     4441 ctaacacaat gcaacaattt gatacagcta tcaacactgg tactgtagac ccagataaag
     4501 cgattccaga attgatggaa aaattgaaat ctgaaggtgc ctacgaaaaa gtattgaacg
     4561 aaatgcaaaa acaatacgat gaattcttga aaaacaaaaa ataatcagct aaattgattt
     4621 cgtgtattca ttcctaactc ctaaaataag aatcactgct ttcctcaggt tggtctgggg
     4681 gagacagtgg tttttttggc acaaggatat agatatccat gttttctctt gtccttattt
     4741 taaccattca ggaaatttcg agaaccctct acaatttcca gtcaaataaa ttgcattcgt
     4801 tttctcaagc aggtatacta gtgtagataa ataaaaaatt tagaaaattt aagaatagaa
     4861 aagagaacaa atcttatggc aaaagatatt cgtgtcttac tttactacct ttatactcca
     4921 attgaaaatg cagagcaatt tgctgcagac cacttggctt tctgtaaatc aatcggtctt
     4981 aaaggccgta tcctagtcgc tgacgaggga attaacggaa cagtttcagg tgactatgaa
     5041 acaactcaaa aatacatgga ctacgttcac agccttccag gaatggaaga actctggttc
     5101 aagattgacg aagaaagtga acaagccttc aagaagatgt ttgttcgcta caagaaagaa
     5161 attgtccacc ttggtttgga agacaacgac tttgacaatg acatcaaccc acttgaaaca
     5221 acaggtgctt acttgtctcc aaaagagttc aaagaagcgc ttcttgataa agataccgtt
     5281 gtccttgaca cacgtaatga ttatgagtat gacctaggac atttccgtgg ggctattcgc
     5341 ccagatattc gcaacttccg tgagttacca caatgggtcc gtgataacaa ggaaaaattc
     5401 atggacaagc gtgtcgtggt ttactgtaca ggtggcgttc gctgtgagaa attctcaggc
     5461 tggatggttc gtgaaggtta caaagatgtc ggccaattgc acggaggaat cgcaacttac
     5521 ggtaaagacc cagaagttca aggtgagctt tgggatggga aaatgtacgt ctttgacgag
     5581 cgtattgccg ttgatgtcaa ccatgtcaac ccaactatcg tagggaaaga ctggtttgat
     5641 ggaacaccat gtgaacgtta tgtcaactgt ggaaatccat tctgtaaccg tcgtatcttg
     5701 acatcagaag aaaatgaaga caagtacctt cgtggatgct cacacgagtg ccgtgttcac
     5761 ccacgtaacc gctatgtttc aaaaaatgaa ttgacacaag ctgaagtgat tgagcgccta
     5821 gccgctatcg gtgaaagctt ggatcaagca gctactgtat aagatcaaac agtcctcagg
     5881 ggctgttttt ctatgctttg tactcaaaaa tctaaagttt gtttctgtat ctttcagaaa
     5941 aataaggtat actgtatgta aacgatttca aaggagtcca gttatggcaa aaacattttt
     6001 tattccaaat aaacagagca ttttaggaga acaagagatt ttgaatgcca agtcgatctt
     6061 ggccttgcta gacggtttgg agtcacatag ctatgatgta gtctatctcc gtcagcctct
     6121 taatcgtctc gagtatattg agtgtgcgat agtggggcaa tcacaatttc tttttaaggt
     6181 cagttatgct gatggtcaaa aggcttaccg tgtcgatctt cctgacctac taacaaagac
     6241 agactggcag attatcaagt catttttaga tgctttgctt gcttatacag ggactgatat
     6301 tgaagggcta gatggttttg attttgaagc ttatttccaa gcaagtattc aagcctatct
     6361 agcagaccct gtagctcgtt ttacgatttg ccaaggaatt tttaatccta ttttctttag
     6421 tcgtgagaac ttgaaaagct ttttagaggc agatggcttg gctcagtttg aagcgcgtgt
     6481 gcgtgcggtt caagagacag atgcctactt tgcgagagtt tccttctatc aggatggaga
     6541 aggaaaagtg catggcgttt accatctagc tcaaggagtc aagacagttt taccgagaga
     6601 accgtttgtt cctgcagcct atattgagca attggtggat aaggaagtgc agtgggagat
     6661 tgacttggtt caaatcacag gagatggctc taaaccagaa gactatgaag ccattgcccg
     6721 cttggactat gcaaaattct tagaggtatt acccctatct ttttaccacc aactagacgc
     6781 caatcaaata gaagtgcaac ccatattaga caaagatttt aaagcattag cacaagaaga
     6841 gtaaagcaga agcaggtcaa tcgacttgct tttttgaaat agaaaaatcc tgccatgaaa
     6901 gacaggattg ctactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgta
     6961 cttgagtacg gtaaggcgaa gctgacgtgg tttgaatttg attttcgaag agtatgaagt
     7021 ttaaagaaag gccaagatac gaagataatc tccaatcagt gccacttcag ctacaaagaa
     7081 gaggaggata ataactccgt tcacaaggac agacaagaat aattgataga aggagtcggt
     7141 ttcacttgct tgacttggtc ttgtaatgat atggagactg gcaagcagaa tgattccaat
     7201 gctaatcaca cacaagaggg ctgtaaatcg taggctatca aagaaagcaa agaaactagc
     7261 aatagcagtg aggaagattg gaattgctaa gagttgacta tattgttgga gaaccttgtc
     7321 tagcgtccag tccttttcct ggtggataaa tcgtctcaca acgaaactac ccaagaggaa
     7381 tgaaaagaag aagagtgttg tcgctactag gatagagatg atagaaaaaa gagttaaagg
     7441 agctagctgc tcagggaagc gactgttaat gcttgctata tgtccatagt aagcatgttt
     7501 gatgtgatag atactaaaga aaaaggaaga tgcagaaaac agaatgagca agagaaaggc
     7561 tgtgtaactg tgtgtgatac ttgtttccaa cttacttgta ggagatttga tcgcttccac
     7621 tagccaagac caaaaatcaa gcacttgctc tttccattta tccctagatt ttggagcttt
     7681 gtcggggata taaggacttt ctaaagattt actgataaga agtggctctt tcgtggttgc
     7741 tttttgctga ggaagagctt cttggctctc ttcagctata gtgacttttt ctgtttcttt
     7801 agaaaggtct ggctcttctt cagtagaatt agatgccttc ttttcttcta tttctgttct
     7861 cgcttcactg tcttcaggag cttcaatttt ctcttcttgc tggctttcca attcgacttc
     7921 agcttgaggg acttcctcct ctaactgagt atttttttca attggtgtat cgagatcggc
     7981 tatcgtttct tcagccttgt ctgcaacctc ttgagcttgc tcttcaggct tgttcttgct
     8041 tgttgttttt acaaaatcat tactttcaaa ccattcttgt ttcatggtag aacctccttt
     8101 ttagttagat aaatatgctt ccatagtagc agatgtaagc gtttttgtca acgtctgctt
     8161 ggtgtggata ttagatcaat attatcatca gatctcgcaa tgagttgatc cttgacatcg
     8221 gttttttcag ttttgtaagg gttgcttaat tccgtacctc ttgattcagg cttttctctt
     8281 gtgaattgga agatagaacc atagttgctt gagatgtccc agttaattcg ttggctttct
     8341 ttctggttta ggatgattct gagataatct ttggcagtca gttcaacctt gccatggact
     8401 tggatatttt cagcgtggaa gtgattctct gttgactcta gctgactatc tgtaagaact
     8461 gtatcaaaga tattaacgat attgggcgtt gtgagtttac tgtttttgat acgacttcct
     8521 tcaattcgga ggatatagct gtttgtattg agggtcgcat tttcaaggct agcatttatg
     8581 atggtggttt gtccgcgatt ggctgagatg ttgatccctt ttagagttct cccttttggt
     8641 agctggagaa taacttcttc aaaacgacta gagtagctac ttgcgatatg aagaatccca
     8701 ccaattccag aagagagaaa cggagtttca gacagtttct tatcagtgag actcagagtt
     8761 ctatcgttct gattggtgat aagatcatgg tgagcagaaa gagatggatg gtaagaaatg
     8821 tggatttgat catcgaaaga gtctgtgatg gtgagcgcgt gttggtggag agtaatttct
     8881 aggttttcga cttccttgcc aaaggttagc ttttccgtac ggctatcata gataggttct
     8941 ttggacatgg aaagtaggct tttaatcccg tcagattgga tacctacaaa aagaaggata
     9001 aagccgataa cggtagtcac cacaccaaag atgagaaatc cttttgtcca tttacgcatg
     9061 ctggttacct ctctttcttt ttttaagaac aaattgtacc aggcgaacaa tgagtagacc
     9121 gaagaagcga gctacatagg aaatgcctag taaaactagc gaagaagcac cgatagccag
     9181 taaaccagaa ccaaaaatca agataaaggc tgatttggct tgggcgagga cagtgaaact
     9241 ttcaactaaa aataggaatc cgccgatgat acccagtatg gaaactgcaa agaaagccag
     9301 aatgacagtc aaagcggcta caaggattgc gaacagggtc acgaggatgg cgattcccag
     9361 aggaatgccg ataggtgctg caaggagggc taacaaggcg atatgtaaaa tttgtcggtt
     9421 atttttttga gcgggtgctt cattgatttt tttatcgaga agattggata gaacttcgtg
     9481 ggccgcttct ttgggagttc ccaaactagc gatgagttct tcttctcctt cgactccagc
     9541 atcgtcaaag agctctctga aatagtccat ggcttcgata cggtcagctt caggtagttt
     9601 cttgagatag agttctagct gagtcaggta ttcagttctt gtcatggcgg atactccctt
     9661 ctatgatgcc attgatggtg tctgtataga gtgcccattc atcttttagg gtcaagagct
     9721 gctctatacc accgtttgtc aaggagtagt atttgcgcat gcgaccttgg aactctctag
     9781 aataggttgt cagaaagcta ttgccttcca attttttgag aatgggatag agtgtggatt
     9841 ctttgatatt agcgatcagc ttaatggttt ggctaatctc ataaccataa gaatcaccct
     9901 gctccagtac ggccaagatg agaaattcaa tcaaggcaga ggatgttgga aagtacatgg
     9961 gaaacctcct tttctaatgt gtaagatttt tatatataat ttttctacac atacattgta
    10021 catctaaaag aaagccctgt caagagaaat gtgtaaaatt tttatatata aaaaacttct
    10081 agctaaaact agaagtttaa aggatcttat ccgctctgtc cactgtaaag agggccacag
    10141 tcatcaggat atcgatgagc aagagggcag ctacagctgg tacccaagag tggaataggt
    10201 caaaactgta accaaagagg gttggcccaa aggctgctag gatatagcct cctgtttgag
    10261 ataggccgga caattgggct gtcttttcag gggcgcttgt cttgagtgaa aagttgacca
    10321 tgagataagg gaagagggcg ctggttgcgg ttccgatgag gagatggatg gcaagccagt
    10381 aaatgaaatt attgattggg aaaaagagca tggaaatgcc gaccacacca gctagtgaaa
    10441 ccagagtgag catgagctga cggttgcgag tagataaact ggttgtcagg cttgggatgg
    10501 tcattgaaaa aggaatgcta atcagagata agatagaagt cagcaagcca gcttcgtgac
    10561 tggatagacc tgcatggata gacatggtag gtaaccaggt catggcggtg taaaagatca
    10621 aggattgaaa acctgaaaag ataataattg cccaaacctg tttattacgc atgaccttta
    10681 tttgactttt ttgtttggtt tgtggagcta gtctatgatt atagcggtga tttgggagcc
    10741 agaccaaaaa agttgctaga cagagtaacg tgaggaggat aagtcctttc caagaactgg
    10801 cttgtgtaat gggcacagct agataggaag ccagagccgt tgcaatcccc atagacgtta
    10861 catataaggt ggtcagaaaa ccaattttct ttggttgatt ggcttggata agactaggaa
    10921 gcaggacatt gatgactgcg acacttgccc caaccatcaa ggttcctaga tagagcaggg
    10981 gcagattgat tagtcgaata agtgagccga tggtcaagaa gaagaggctg taggtgaaga
    11041 gatgctccaa gccgattttc tgagccagtc gggtagaaaa tggtgaaaag agggtaaaca
    11101 taaggagagg caggctggtc aagacaccaa gcgaactaac ttctacctcc agaccttgcg
    11161 aaatatttcc caaaataatg ggtaaaacag taaaaggagt tcgcaaggaa acaccaatca
    11221 ggataatacc tggaacaaaa aagagtgatt gctttttcat ataatatctc ttctagctga
    11281 ttttaataac agcttatttt aaggcttttt cactataatg tcaagtaagg tttctggctt
    11341 tcaagataaa aatggaaaag tcttgaaaat tatgatagaa tggtggaagg gaaaattcag
    11401 gagagtagta gtgactcaaa atgttgaaag tcttctcgta tccattgtaa tcagtgcata
    11461 caatgaagaa aaatatctgc ctggtctaat tgaagactta aaaaatcaaa cctatcctaa
    11521 agagaatatt gaaattctat ttataaatgc tatgtccaca gatgggacca cagctatcat
    11581 tcagcaattt ataaaagaag atgcagagtt taactcaatt agattgtata acaatcctaa
    11641 gaaaaatcaa gctagtggtt ttaacctggg agttaagcat tctgtagggg gccttatttt
    11701 aaaaattgat gctcattcaa aagttactga gagttttgta atgaacaatg tggctgttat
    11761 tcaacaaggt gaatttgtct gtggagggcc tagaccgacg attgtcaaag gaaaaggaaa
    11821 atgggcagag accttgcatc ttgttgagga aaatatgttt ggcagtagca ttgccaatta
    11881 tcgaaatagt tccgaggata gatatgtttc ttctattttt catgggatgt ataaacgaga
    11941 ggttttccag aaggttggtt tagtaaatga gcaacttggc cgaactgaag ataatgatat
    12001 tcattataga attcgagaac atggttataa aatccgctat agcccaagta ttctatctta
    12061 tcagtatatt cgaccaacat tcaagaaaat gctgcatcaa aagtattcaa atggtttgtg
    12121 gattggcttg acaagtcatg ttcagtttaa gtgtttatca ttatttcatt atgttccttg
    12181 tttatttgtt ttgagtcttg tgtttagtct agcattgtta ccgatcacat tcgtattcat
    12241 aactttacta ttaggtgcct attttctact tttatcatta ctgtcattac tcactttgct
    12301 gactttatta aaacataaaa atggatttct aattgtgatg ccctttcttt tattttccat
    12361 tcactttgct tatggccttg ggacgattgt aggtttaatt agaggattta aatggaagaa
    12421 ggagtacaag ggaacagtaa tttatttgga aaaataagcc aaataaatta aaatgtgcta
    12481 taataacaat atagtagaac tattttaagg aggagtaaat ttctatgaat aaaaaactca
    12541 cagattatgt gattgatctg gtggaaattt taaataaaca acaaaagcag gttttctggg
    12601 gaatatttga tattttcagt atggtggttt ccatcattgt atcttatatt ttattttatg
    12661 ggctgattaa tccagcacct gttgactaca ttatctatac gagtttggcc ttcctgttct
    12721 atcaattgat ggttgatttt tggggcttga gcgcgagtat tagtcgttac agcaagatta
    12781 cggatttcat gaaaatcttt tttggtgtga ctgctagcag tgtcttgtca tatagtatct
    12841 gttatgcctt cttgccactc ttctccatcc gttttatcat tctctttatc ttgttgagtg
    12901 ccttcttgat tttattgcca cggattactt ggcagttaat ctactccaga cgcaaaaaag
    12961 gtagtggtga tggagaacac cgtcggacct tcttgattgg tgccggtgat ggtggggctc
    13021 tctttatgga tagttaccaa catccaacca gtgaattaga actggtcggt attttggata
    13081 aggattctaa gaaaaagggt caaaaacttg gtggtattcc tgttttgggc tcttatgaca
    13141 atctgcctga attagccaaa cgccatcaaa tcgagcgtgt catcgttgcg attccgtcgc
    13201 tggatccgtc agaatatgag cgtatcttgc agatgtgtaa taagctgggt gtcaaatgtt
    13261 acaagatgcc taaggttgaa actgttgttc agggccttca ccaagcaggt actggcttcc
    13321 aaaaaattga tattacggac cttttgggtc gtcaggaaat ccgtcttgac gaatcgcgtc
    13381 tgggtgcaga actgacaggt aagaccatct tagtcacagg agctggaggt tcaatcggtt
    13441 ctgaaatctg tcgtcaagtt agtcgcttca atcctgaacg cattgtcttg ctcggtcatg
    13501 gggaaaactc aatctacctt gtttatcatg aattgattcg taagttccaa gggattgatt
    13561 atgtacctgt gattgcggac attcaagact atgatcgttt gttgcaagtc tttgagcagt
    13621 acaaacctgc tattgtttat catgcggcag cccacaagca tgttcctatg atggagcgca
    13681 atccaaaaga agccttcaaa aacaatatcc gtggaactta caatgttgct agagccgttg
    13741 atgaagccaa ggtgcctaag atggttatga tttcgacaga taaggcagtc aatccaccaa
    13801 atgttatggg agcaaccaag cgcgtggcgg agttgattgt cactggcttt aaccaacgta
    13861 gccaatcaac ctactgtgca gttcgttttg ggaatgttct tggtagccgt ggtagtgtca
    13921 ttccagtctt tgaacgtcag attgctgaag gtgggcctgt aacggtgaca gacttccgca
    13981 tgacccgtta ctttatgacc attccagaag ctagccgtct ggttatccat gctggtgctt
    14041 atgccaaaga tggggaagtc tttatccttg atatgggcaa accagtcaag atttatgact
    14101 tggccaagaa gatggtgctt ctaagtggcc acactgaaag tgaaattcca atcgttgaag
    14161 ttggaatccg cccaggtgaa aaactctacg aagaactctt ggtatcaacc gaactcgttg
    14221 ataatcaagt tatggataag attttcgttg gtaaggttaa tgtcatgcct ttagaatcca
    14281 tcaatcaaaa gattggagag ttccgcactc tcagtggaga tgagttgaag caagctatta
    14341 tcgcctttgc taatcaaaca acccacattg aataaaaaag aaaaacgcat attatcaagt
    14401 taaataacct tggtaatatg cgttttatta tgtagagact tatactcttc gaaaatctct
    14461 tcaaatcacg tcaacgtcgc cttgccgtat atggttactg acttcgtcag ttctatccac
    14521 aacctcaaaa cagtgttttg agctgacttc gtcagttcca tctacaacct taaaacagtg
    14581 ttttgagcag cccgcagcta gtttcctagt ttgctctttg attttcattg agtattactt
    14641 cattttcttc tgaaatagag ttgtcgccca gtctatgcta ttgaaaatac gccaaaactt
    14701 ctaagggttt gtgagcgata taatcaggtt gatagtttag tagatctgct tgctctccaa
    14761 atccccaagt gacggccaat ttctgaatac ctgtttctcg agctcccagc atatcaaact
    14821 tggtatctcc gatgatgatg gcttgttctg gtgctagttg atgtgtctgt aaggcttggt
    14881 gaatgacatc tgccttatgg ggtgcttcag ggctagaacc ataaatacca tcaaagaaat
    14941 gatggatttc caagtttttg gccatgtctt gagcagtaga tgtattcttt gtcgtggtga
    15001 tgtagagtgg ataactgctc gataactcct caagcaagtc tataatctga ggaaagagtt
    15061 gagcttcata gatgcctttt gccttatagt aagaacgata tatctgcatg gcttcagaaa
    15121 tttggtcttt ggacaggcag gtcgcaaaac tactttcgag aggtggtccc ataaaaccac
    15181 gaatagtttt ggcatcaggg ctaggcaccc ccagctcttt aaaagtatag gtaaaggcat
    15241 tgtgaatccc gatagaacta tcaacgaggg ttccatccaa atcgaaaaaa atcgctgtga
    15301 tagaggtcat ggtttctcct atttgataag cttattctcc gaaaatctct ttttggaggc
    15361 gacgaccagt aggggtggta gcgagtccac cttcagctgt ttcacgaaag gcagttggca
    15421 tgcttgctcc tacttggtac atggcatcga tcacttcatc cacagggatt ttagattcga
    15481 tacctgccaa ggccatgtct gctgcgatga aagcaaagct agctcccatg gcattacgtt
    15541 tgacacaggg aacttcgacc aaacctgcaa cagggtcaca gatgaggcct agcatatttt
    15601 taatgacaaa ggcaatagct tgactggcct gataaggtgt tccacctgca gccagagtca
    15661 aggcggcagc actcatagca gaggctgaac caacttcagc ttgacaccca ccctcagcac
    15721 ctgagatgga ggcattgttt gcgatgacta gtccaaaggc accagcagca aagaggaaat
    15781 ccaattgttg ctcgtggctg aggtctaatt tttcaatagc agcagtgaga acggaaggga
    15841 gacaaccggc acttcctgcg gtaggagtag cgcagaccaa gcccatttta gcattgtgtt
    15901 cattgactgc gatagcattt cgggcagcag agagaatcgt gtaatctgat aaagtttttt
    15961 cgtttttgat gtagtgatcc aatttggcag catctccacc tgtcaggcca ctacgagatt
    16021 tattttcatt gaggccaagt tggacagagg ctttcataac ttccagattg cgttccatga
    16081 gaaggaagac ttcttcacgt tcgcgaccgg tcaattcaaa ctctgttgta atcatgagtt
    16141 ctgcgacatt tccttgaaag tccagatctg cttgctcgac caattctttg atagaataaa
    16201 acatgcttcc tcctatttaa agaaattgac attgtggaga tgagggattt ttcgaatttc
    16261 ttcgatagcc tcatcacagt tgcgactgtc aacttcgata atcataatgg ctttttcacc
    16321 agctttttca cgagtgacat tcatctgggc gatattgata ccatagcggg aaagcgcctc
    16381 tgtaacaagg gcaatcatac ctggaatatc ttgatgaacg atgatgatag tcggtgtatt
    16441 catattgaga gagacggcaa aaccattgag ttcggttacc tgaatatttc ctccaccgat
    16501 agaaatacca gtcacgctga tggtcttgtg ggcattttta acagtaattt tagtggtgtt
    16561 agggtgaggg gcattgctgt ctttctgaat ggtccagaca atcttgatac cacgcttgtg
    16621 ggcaatttcc agactatttg gaatttcagg atcatctgta tccattccta aaatacctgc
    16681 aacaagggct aggtctgttc cgtgaccacg ataggtcttg gcaaatgagt taaaaagttg
    16741 gaattcaact tctgtcggag tatcatcaaa aatggaagag acaatcttcc caatacgaac
    16801 agcaccagcg gtatggctac tagatgggcc aatcataact ggtccgatga tatcaaagac
    16861 agattgaaaa cgaagtgatt tcatcagttt ccccttataa aaattcttat ctctattata
    16921 tcaaagaatg aggggcttgg ctttaattgt ggatgaaaac ctttctaata cctcaaatag
    16981 cataaaaata gtatctttta tgacaaaaaa caccttattt agggaaataa aaaataattt
    17041 tgtaatattt ctacataaaa gtgtcaagaa acggtaatat ttaaagggta tgatagaact
    17101 atagaaagaa ggagaatttt cgaatatgaa atcaataact aaaaagatta aagcaactct
    17161 tgcaggagta gctgccttgt ttgcagtatt ttctccatca tttgtatctg ctcaagaatc
    17221 atcaacttac actgttaaag aaggtgatac actttcagaa atcgctgaaa ctcacaacac
    17281 aacagttgaa aaattggcag aaaacaacca cattgataac attcatttga tttatgttga
    17341 tcaagagttg gttatcgatg gccctgtagc gcctgttgca acaccagcgc cagctactta
    17401 tgcggcacca gccgctcaag atgaaactgt ttcagctcca gtagtaagtg aaacagttgt
    17461 ttcaactgta agcggatctg aagcagaagc caaagaatgg atcgctcaaa aagaatcagg
    17521 tggtagctat acagctacaa atggacgtta tatcggacgt taccaattaa cagattcata
    17581 cctgaacggt gactactcag ctgaaaacca agaacgtgta gcagatgcct acgttgcagg
    17641 acgttacggt tcatggactg ctgctaaaaa cttctggctt aacaatggct ggtattaaga
    17701 actaacgaac aaataatatg taaagagtcg aggaaatccc tcggcttttt tatctttcct
    17761 tcgcttggta atagatctct acttcttttt tgagatgaga cagcatagaa gtttcctcgg
    17821 ttagctccag aagggagaac cctttttgga taagtttaga atcgtctgta caaatcccaa
    17881 tacggacata gcagatagcc agcctatcgt agcttttctt attcttggcg tcctctagta
    17941 aagtgtagca gatttgctta cacatgtttt tatcttgatt gtatagatag agtgtggaaa
    18001 ggttgagcag gattgctatt tgcaagtcat ataaatgttg atagttttta tagacttcta
    18061 agcgttgcaa gattttctcg gattattgac aaataaacgg acattctgat agacgattgc
    18121 cctagcggct tagtgtaaac tttacaaatt tggcttgtaa tttttttata aaattcactt
    18181 cagttacttg acagttatta tattttcact tattatatag ataaaaggat gagatgggag
    18241 tttaaaaatt tgaaagcgct atccatattg tttattggac tgattcttga gtaatagtta
    18301 gagtgtgctt aatactactc tggttgttca aggacctgat acagaagcgc accattctct
    18361 cggttaagag taagttcgtt gttaaaaaat gaaatgagat agaaggaagg tgagtccaat
    18421 ggactacgat acttgttgat aaattactat agctgttttt acggaagagc tctcgataat
    18481 aggagaaata aatcatgaga aaattagtta aaattggtgt tgcatcttta atggtatgta
    18541 gtatacttgc ttctacaagt gttttggcag tatgggttga tggtggtcaa tggaactatg
    18601 gagtaggatg gtcaggaaat tttggttatt ctgattattt acattctact cgctctcata
    18661 cagcaactgt taaagatgga aataaattct ctaaggatcg tgcagaagct gaggcatggg
    18721 ctcgggcttc aatcttcaaa ttcccaccaa cgggaatgga atatttctat ggattttaat
    18781 taaaattctc cctccccttt tggagaggga gtttcttcac gggaggtatc tctatgaaaa
    18841 aaatcagtca tctttgtatg ttactcctgc ttctgtgtac cacttttttt gtttttaatg
    18901 taaactatac acgagaagtg gttcggattc aagaaatggg aaagactgta gattctttgg
    18961 atttgtattt gaaagatatt aacgaacctg cagcgtctgt tcttcgattt tttgaggatg
    19021 tatcaaagga gtataaagtc tccatcatca aaacagacag tggtgatgag gtggtcaagt
    19081 ctggtgtttt tgataaagat accttcccct accaagagtt tgggatttct tctcttgatt
    19141 ttaccacaga tggtgaagga gtctatagta ataaagaaat ttccaataaa cttggtacga
    19201 ttccgacctt tctaaaagcc aaacctattc agcttatgac ttttcaaacc tatatcaagg
    19261 atacatctcg tagtttaaat ggtcgctata cgataacttc tacacaagag atggacaagg
    19321 ataggattgt acagaaatgg agcgattttt tcaagataga ccaggctacc ttgctagagc
    19381 cgacctacaa aagtgcagtg gaagtcataa atcgagattt gcttttatct gccattgttt
    19441 ttgtcttggc tattttgctt cttgtgttag tgacagtgta tcaaccgatg atggagatga
    19501 aaagagttgg ggtacaaaaa ttacttggtt ttcaagatag ggctgtttta gctgatgttg
    19561 taaaaggcaa cctttacctc ctcctaggtg gggctcttgt gatcaatcta ggcgtgtttt
    19621 tcttgcttga ttataagcca aaagatttgt ttcctatgct gtggttgtct cattttttgc
    19681 tgttgcagct ttatctcttt atcagttggt tgacttacct cttaatccaa aaaatgacaa
    19741 tcagctctct gctgaaaggt ttttcatctt tcaaatttgg tctactcttt aattatttga
    19801 tgaaaattgg aactaccatt ttactgacag tcttgctagt tggggtagga aaaagtttgg
    19861 agcaagaaaa caaagagttg gattaccaga aacagtggat cagccaagga aattatctga
    19921 ccttagaaac tttccaactc aatgataact tgtggcaaga gcagttggca ggctcaggga
    19981 aggcattgga ttatttctat cgattttatc aggatttggt agaaaaaacg caggcgggct
    20041 atgtgcagag tagcagtctt cctgtaaaaa attttgtcca atcagaacag attcagcaat
    20101 atcagttaac agatacggtg gatgtttact atgccaatcg caattttcta aagagcaagg
    20161 gattcaagct accagatacc ggtattaaaa aagttatttt gatgccagca agtacgaaag
    20221 gtgaagaaga taaaaatcag ctcttgggga agttaattgc ctttcattcg atgaagtatg
    20281 aagagcagca aaaacgaacg atagaggaga tggatgtcga gattgcctat tatgaaggag
    20341 attggtcatt tttcccatat agtgataagc gaaaggaaaa tctctccaat ccaattatta
    20401 gcttggtcaa tgattctgat atgatgtggg atgagaaagc ctccctgtca acaactggct
    20461 taaataatcc gattaaaatt gaaaatacgg ttcaacatca aaaagagatt acagagttag
    20521 ttgagaaatt gtcagatgga aattatttaa aattttcatc tattcaagcc attcaacaag
    20581 agaaagtgga ttcttatcga gatgctgttc ggaattttaa cctactcttt gctttgtttg
    20641 gtctccttag catgatgatt tcctacttct tactagtaat aactttctta ttgaagcgca
    20701 gggatatcat taccaagaag tttatggggt ggaaactggt cgatcgctac cgtcctctcc
    20761 tcgttctgct cttgctgggc tatagtttcc ctcttctagt cttgattttc tttgcccatg
    20821 cgttcttgcc acttctgctg tttgcaggct ttacatgttt ggatatacta tttgtgctag
    20881 tcttggcttc taggatggag aaaagaagtc tagtagagtt attgaaaggg ggcatcttat
    20941 gattgagttg gaaaatatta ccaaaaccat tgggggaaaa gtgattttgg atcacttgtc
    21001 tctcaggatt gatcaggggg atttggtagc tattgttgga aaaagtggta gtgggaagtc
    21061 gaccttgtta aatttattag gtttgataga tggtgattat agtggacggt atgagatttt
    21121 tggtcagaca aatctagcgg tcaattctgc taagtcgcaa acaataatcc gtgaacatat
    21181 ctcttatctg tttcaaaatt ttgccctgat tgatgatgaa acggtcgagt acaatctcat
    21241 gctggcgctg aaatatgtga aattgtctaa gaaagacaag ctcaaaaagg tggaagagat
    21301 tttagagaga gtaggtttgt catctacttt gcatcaaaag gtttccgagt tgtctggtgg
    21361 cgaacaacaa cgaattgcag ttgctagagc catcttaaaa cccagccagc tgattttagc
    21421 cgatgaacca acaggttcgc tagatcctga aaatagagat ttggtcttga agtttctctt
    21481 agagatgaat cgcgagggga aaacagtcat tattgtgacc cacgatgctt atgtagccca
    21541 acaatgtcat cggatcattg aattgggcga ggggaaatga gtttgttcag ctctttttga
    21601 ctgactgaat actcatgttt ttcagagagg aatagcataa atacgcctag aaatgacatt
    21661 tttatgtagt atttctaggt ttttttgttt caaattgaaa atttttccaa tttaggcttg
    21721 acaaaggatg aagataggtg tattatttat acaaccaaaa agaataaaca taaaggagac
    21781 tttgttatga ataagatgaa gaaggtgttg atgacgatgt ttggtttagt gatgctcccc
    21841 ctactatttg cttgtagcaa caatcaatcg gctggaattg aagccatcaa gtccaaagga
    21901 aaattggttg tagccctcaa tccagatttt gctccatttg aataccaaaa agtggttgat
    21961 gggaaaaatc agattgtggg ttcagatatc gaattagcca aggctatcgc aacagaacta
    22021 ggtgtcgaat tggaactatc tcccatgagt tttgataatg tactggctag tgttcaatca
    22081 ggaaaagccg accttgccat atcaggtgtt tctaagacag atgaacggag caaggtgttt
    22141 gacttttcca ttccctacta tactgcaaaa aataaactca ttgtcaaaaa atctgacttg
    22201 actacttatc agtctgtaaa cgacttggcg cagaaaaagg ttggagcgca gaaaggttcg
    22261 attcaagaga cgatggcgaa agatttgcta caaaattctt ccctcgtatc tctgcctaaa
    22321 aatgggaatt taatcacaga tttaaaatca ggacaagtgg atgccgttat ctttgaagaa
    22381 cctgtttcca agggatttgt ggaaaataat cctgatttag caatcgcaga cctcaatttt
    22441 gaaaaagagc aagatgattc ctacgcggta gccatgaaaa aagatagcaa ggaattgaaa
    22501 gaggcagtcg ataaaaccat tcaaaagttg aaggagtctg gggaattaga caaactcatt
    22561 gaggatgcct ttaaagcatc cattgaaaaa tagaaagaag gaaaagaaca tgagtaaaga
    22621 aaaagtaatt ttggcctatt ctggcggttt ggacacatca gttgctatta cctggttaaa
    22681 gaaagactat gatgttgttt cagtttgtat ggatgtgggt gaagggaaag acttagactt
    22741 catccatgat aaggctctca aggttggggc agtcgaatct tatgtcattg atgtcaagga
    22801 cgaatttgct acagattatg tgctagtggc tcttcagtca catgcctatt atgaacaaaa
    22861 gtaccccttg gtatctgcct tgagccgccc tcttatttct aaaaaattag ttgaaatagc
    22921 gcatcagaca ggagcgacta caattgctca tggctgtacc ggtaagggga atgaccaagt
    22981 cgaataccag attgcagtcg ctaagaaagc gaatgaagct aaaaagtgat ggagtgatgg
    23041 gttcagaata agaggttggt cgattggtag cctctttctt gtcgttgaaa aagtgagata
    23101 tattgacttt tgaaaaaaat gtcataattg agttgggata aacgtaaaag tcatactttc
    23161 tcgttaaatc gttcggcgat tcatggtgac atggacacat agtagtaaac acactatgtg
    23221 gcttggcaga gctaaaaact tctggcttaa caatggctgg tattaagaac taacgaacaa
    23281 ataatatgta aagagtcgag gaaatccctc gacttttttt ataatttctt tggttgataa
    23341 tgggtctcta cttctttttt gagatgagac agcatagaag tttcctcggt cagctctagg
    23401 agtgagaacc ctttttggat aagtttagaa tcgtctgtac aaatcccaat acggacatag
    23461 cagatagcca gcctatcgta gcttttctta ttcttggcgt cctctagtaa agtgtagcag
    23521 atttgcttac acatgttttt atcttgattg tatagataga gtgtggaaag gttgagcagg
    23581 attgctattc gcaagtcata taaatgttga tagtttttat agacttctaa gcgttgcaag
    23641 attttctcgg attattgaca aataaacgga cattctgata gacgattgcc ctagcggctt
    23701 agtgtaaact ttacaaattt ggcttgtaat ttttttataa aattcacttc agatacttga
    23761 cagttattat attttcgctt atgcttatta tatagataaa aggacgggat aggagtttaa
    23821 aaatttgaaa gcgctatcca taataataac gcataatttt ctccttttcg tgaaaaaagt
    23881 taacgtaatt ttaaaatgag cttaataaga ggtactatgt aggtagaaaa taaagatagg
    23941 agaaaaagta tgaataaaaa aatattttgt attctggtat gtattatatc attgattagt
    24001 ctagctataa tctttccatg gggctggtcg atataatgta agggagcttg agttgttagt
    24061 ggaggataaa atgttaagag taatagtagt tattcaatct ttagtaataa tactgcttgc
    24121 tgttgcttta ttattatctc ggaaaaactt tgattcgtta aatgttgttc ttataatgat
    24181 gatcgtatca caattgttgt tattagtata tttgataaaa tcagggaatc agtgattagc
    24241 tgttatttga attaagtaaa ctgttaagct tcaagcagta actggtttta aatatttaaa
    24301 ataagataaa ggaaggaagt ctaatttagg taactaaaca aagcctgcga tcacttgtta
    24361 ggaaactatc ctaaccatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
    24421 aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg tggtgttggt
    24481 cgtaactggt ggaatagtag aggtagtttt gcaacagttt tggatgtagg tttggccatc
    24541 tatagtggtg gtgcaacaat ttattctgct tatgcgataa aaaaagctat ctcagctaat
    24601 agaggggcta ttacgagaac attacgtagt ttaataatta aacatgtagg tagtgcagct
    24661 ggccatttag tcaatactgc actaaacgtt gcactaactg ttactggatt ttcactaggt
    24721 ggagcaatcg catatggggc tgattgggct gacggtagct tagatggtta tatttttgct
    24781 taaaatgaaa catttttttg caggaattgg tgaaattcat tttttgttat ttttattata
    24841 tctaagcatg tctgctagtc caattattgg actagtgatt ggatatacta aaataaatct
    24901 aataaattct attattatag ctcttggtat gatattggca ttaattttgg tattatcaag
    24961 agtgtataga aaatattttt atagagacga tgatgactaa agtttttatc aataatttgg
    25021 gctccttgtc aactgtagtg ggttgaagaa aagctaacgt ctggggaagg ggttaaagct
    25081 ttgctttatc aaatattgac ttacagagtt gctctattgt attgatgtat tcttagtaaa
    25141 taatatggtg ttttgaatga aagatgatca gaaatattta ttagcgggac tttattcgct
    25201 tctagttgca atattttatt ttccattgat tgagtccaag gggatttttg taagtatatt
    25261 gatggcggtt ttacttttat atttaatata cttcattgga acagtcattc atattgtgat
    25321 aattaagttt ataagaaaaa aatcttttaa gtatttggtt ctatatccat ttacttatga
    25381 tgggagctgg agatttcaac ctataaactt actctacttt ccagaaatgg tgagagatgt
    25441 cattccgatt aatttagttc aagaatattg ccaaggacaa ccttacgggc tgttaaaaaa
    25501 gatgctgaaa agaattcgat tgtcacgaga gatagcttta ctcctggcta ccattatcgt
    25561 ctattttttt acgcatagaa ttctacctct ttcagtattt acgttcatgt tttcttacat
    25621 attgatattt gcacaatctt atttgggtgg taatactgct tggattggaa atagaagatt
    25681 aataatagat gatgaatttg aaaaaatctt gctttcaaaa agttatataa aagaaatatc
    25741 atctgcacga tactcggaat acttgacatg tgaatacaaa aaccttacac caatcatatt
    25801 gttagctatt tttgaaaatt tacttgactc ctacttgctt cagaatcaga gtgaggttga
    25861 cttagatatt ttttataaag ttttaccttt gctttataaa gaaaaatata ctatgggatt
    25921 caattacttt gtaagtttaa attatttact atataaggtt ggatttttgg gaatcattta
    25981 cgataatgaa gcattaggag atttgtcaaa acaatattta aacagaaata tttcggaatt
    26041 acaagatggt tctttcgagg gcggtataca agatgctgtt gcctctaaac aaatagtagt
    26101 tataaatgaa tttatagctt gtttaaattc cagatgcatg ccatcccaat atgatagatt
    26161 tttttataaa gatagacctt atattttttc cagaaagagt cctattaaga ggtgaaaatt
    26221 tgttacattt ggattaacaa gtgtcctagg gattagaaat aactctagta tagctagata
    26281 tttttgagta actagaaata tcattaggct acccatatga ttgccagaaa agatggctga
    26341 tgaatcttat ttatactgtt gcagtaggcg ttgtctagga taaataagct atcttgatgg
    26401 gggagattgg aataatttta gtagaaacat taaaggatta tgggcaagta gcacaggatt
    26461 aggtgatgca atgtgctaag ttggcttggt gttagcagta gtattattta acaatggaaa
    26521 gtagactaaa tgaaaaataa acgttatttt tttgacacaa ttttaatgat tttactactt
    26581 ataagcacga tattttgtgt cagcccagta tttataaaat tggacatctt aggaactccc
    26641 tctcatgcca tcttaacctt tgtattggcg ataccgttat tctatatttt gtctcaatgc
    26701 ttacatactt tgctattact agtttcctca atcttttgta aattaagacc aatttatttt
    26761 tattttatat ttgtgatcat tataggagct aggaaatact atcgaattct ctttcaccaa
    26821 ctaatgggat ttagtccagg aatagcagtg ttttataagg agagtcaaac aactaagaat
    26881 ctgtttaaat tttactactt cttgtacttt acaacactaa tttcatacta ttttttcttt
    26941 acttttgtgt atgacaaacc gttgcttttg cctcttattc cattttctat tatcatagca
    27001 ttagtacaaa aactttatag aattgagaat cagcaattat ttctgttaaa atcaaaggta
    27061 ctaacaatac tggaatctaa gaagaattgt gagtttaatc ttcaggatta tcatgaaatt
    27121 tggaaattgc aatcaaaatc tgagttgcca tgcgtggctt tatcttatat cagtttgatc
    27181 aagccatatc tttcagagag cgtgcgtgaa caaattgatt tattagaagt taagcgattt
    27241 aaaaaaataa atcatccaat atcactttat ggtatgttgg atgttataaa attaaatcta
    27301 tatttacggc attataatga aaaaataaat atgaatcaat gttaaagaaa attttagagg
    27361 taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat agctcgcaac
    27421 cattatcttt atctttagct atttcagaaa tccaactttt gcttgaagtg tatataggga
    27481 tcaaacatgt ttcaattagg agataaaact agaataacat ttgctattat aggggcaagt
    27541 tgcatattag tcagtatgta tcttatacct ctcattaaca cggataataa attttgggaa
    27601 atacttttat ttataatagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa
    27661 taaattttga aatagtatta gtgagttcgc aatcatttat tgctagtggt ttagaactgt
    27721 taagtttcaa gcaataattg gttttaaacc ttaggtaacc tataaaaaca aataaggtag
    27781 agaaaggata tcttatttag gtaactaagt actataaaca cagtcgacaa tcacttgtta
    27841 ggaaaccatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
    27901 aataattatg ttgctcttga gcaagaagag atgatgtatt ttgatggggg attttctatt
    27961 ccgagatggc ctgttgcaac agccattaat atagctttta atgatgtctt aggtggagga
    28021 gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca
    28081 attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt agcaggattt
    28141 gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcaatgc tattacaaca
    28201 atctgggcca ataatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta
    28261 gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata
    28321 tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa gttgattatt
    28381 tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga
    28441 aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc
    28501 cctctttttg tcttgtggct agagttgcat gtcctagtga ataacttact attgaatcta
    28561 gaatctcccc ttgattttgt gattagtatg agtcttgctt tctgtagttt gattttatca
    28621 aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt
    28681 acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat
    28741 ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt
    28801 tttattcttg aaattgctat tatcctagta tttattttaa aaattccttt tgcaatcatc
    28861 atgcttacta caatattttt ctggactata atggatatca atcatctcgt ttttaataag
    28921 acggaatttc tttttaatca aaacaaatgg caaaaagaag attcgtttga aagtgatttg
    28981 acgaaaacgt taaaggataa gatacaaaaa tcagagctaa gttattctga cttaatgtct
    29041 cttcagctgt atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag
    29101 gatattttga aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag
    29161 ttactgctgt atgaaatttc tattagtaac aataacaact ggcaagaaaa ggttgataaa
    29221 attagaatac agctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta
    29281 aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta
    29341 ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt
    29401 tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga
    29461 tgaagaagaa atgatgtatc ttgatgggga agcttattta agcaagcgtg cttgtcaagg
    29521 aatttgcgca gctttagcta tgagttcagg aacttttata gcattagctg gagctgcagt
    29581 tttaaccaaa aaactaataa actatattaa ggttggaggt cttggaggct ggcttattgg
    29641 tgcagcagca ggtgtattgg ctacagcagc agggaaaata gcttactata ttggatatgg
    29701 tgttcttaat agaggttgtg atattaacgg gaacccttat ccttgggatg gattcatatc
    29761 tgcgacagta aaatgagtaa tgtagataag attcgaaaaa tacacattat cgtatgttgg
    29821 atgtatatat ttttatcatt cagggcgatt ataaatgaca cggagtattt tttgcttatt
    29881 tttttagctt ttatctactc aatagtatca ctacctctat attctgtgaa aaataaaata
    29941 gtatctatct gtctagccat aaattcgatt ctgttaatga gtttccccat tttaatcaat
    30001 aagtttttcc cagaaagttt tttgacttat accgtattaa taagtgtttt tattacagag
    30061 ttgataattt ttcatttaat tgggaaagat tttgatatta aattgactaa cgaatataag
    30121 aaaattagtc agtttagaag caaggtgtct caatctcctt ggataaaata tttagagatt
    30181 tctagtttta tattaactat atttccatct attctttatg gtacagttga taatcatgta
    30241 ctgactctta tctttttgat aaaaatttgt gcagatacca cgataaaatt tttattcatc
    30301 agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt cgcattggat
    30361 gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg ctatttgttt
    30421 tcggttttac ttcttttttc taatttttca gttccattta tcaaagaaaa ggaattcgaa
    30481 ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc ttaaaatcag
    30541 atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac aatcgaggat
    30601 cacttgttag gattacattt taatcatgct taataagaat ggagaattcc tatggggatt
    30661 gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctatt ctaggtttag
    30721 aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcccg aaaacattta
    30781 ttttatagca attctaggct tagaattgct catatatatg tatttgagct gctcgatagt
    30841 taggatagct ctattctgag aaatctgagc tatcaatgct tcagaatagt attcgccaat
    30901 ggtttttatt gaagaggtga ttgttttatg atagtctaaa ataaaactga tttaatagag
    30961 taaatggaga atcgttacat gaaacatttt tttgcaggaa ttggtgagat aaaacttgtt
    31021 ggctacttat tgtatatatg tgtaggacta gctcctcttt ttcatatata tgtcataggt
    31081 tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttatatt tgtaagtatg
    31141 ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac ttgaactgta
    31201 tctaaaaaca gaggttggtc gattatcagc ctctttcttg tcgttgaaaa gagtgagata
    31261 tattgacttt tgaaaaaaga tgtcataatt gagttgggat aaatctaaaa ataatatagt
    31321 agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat taatttgact
    31381 ttcctaatcg atttgttcat atcttgtttc aatctactat actttctcgt taaaccgttc
    31441 ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt ggcagatcta
    31501 aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga gaagccgact
    31561 ctaatcaacc actttgggca gtagtgagaa ctgccccgtg ctttttattt tgagaaaata
    31621 tggagtttgt cgttgaaatt acttgattgt attttggatt atcaagaaag attcaatgga
    31681 aaaacatgtc aagtatcaac gaattataag tatttagaga ctttcaaagt gaatttttgc
    31741 ttgactgatt tacatcattt atttgactta cacaaaatca cacgagatta tgctagtcaa
    31801 acaaaacctg ctattcaagc tggtgttttt attttagaag attttagaaa tatcctatgt
    31861 acaatgatgt aatcgaaagg atatctttat gtgagtttat cggcgatatc ttctatatct
    31921 aagctagcaa gttgttgcat cgtagctaag gatttatcta aaaatactat gaaattggac
    31981 gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg aagagacaaa
    32041 agcggagtat ttaaaccagt tactctacat tttacaagcg ctaagaaata tgctaaagtt
    32101 cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg cttaagcttg
    32161 cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat gtttttatag
    32221 gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa agtagtgtct
    32281 ttatcttttt ggagtagaag cttatgatat agaaatttgt aataaaaatg taatataaaa
    32341 catttgacaa atatttacgg ggggagtata cttaatataa gtatagtcta aaaatgacta
    32401 tcagaaaaga ggtaaattta gatgaataag aaaaaaatga ttttaacaag tctagccagc
    32461 gtcgctatct taggggctgg ttttgttgcg tctcagccta ctgttgtaag agcagaagaa
    32521 gcccccgtag ctagtcagtc taaagctgaa aaagactatg atgcagcgaa gagagacgct
    32581 gagaatgcga aaaaagcttt agaagaagca aaacgtgcgc agaaaaaata tgaggatgat
    32641 cagaagaaaa ctgaggagaa agcgaaaaaa gagaaagaag cttctaaaga ggaacaagct
    32701 gcaaatctga aatatcaaca agagttggtt aaatatgcta gtgaaaaaga ttcagtaaaa
    32761 aaagctaaaa ttctgaaaga agtggaggaa gctgagaaag agcataagaa aaaacgagca
    32821 gaatttgaga aagttagatc agaggtaatt cctagcgcgg aagagttaaa aaagactaga
    32881 caaaaagcag aagaggctaa agcaaaagaa gcagaactta ttaaaaaagt agaagaagct
    32941 gagaaaaaag ttactgaagc caaacaaaaa ttggatgctg aacgtgctaa agaagttgct
    33001 cttcaagcca aaatcgctga gttggaaaat gaagtttata gactagaaac agaactcaaa
    33061 gggattgatg aatctgactc agaagattat gttaaagaag gtctccgtgc tcctcttcaa
    33121 tctgaattgg atgccaaacg aactaaacta tcaacacttg aagagttgag tgataagatt
    33181 gatgagttag acgctgaaat tgcaaaactt gaaaaaaatg tagaatattt caaaaaaacc
    33241 gatgctgagc aaactgaaca ataccttgct gcagctgaaa aagacttagc tgataaaaaa
    33301 gctgaattgg agaaaactga agctgacctt aagaaagcag ttaatgagcc agaaaaacca
    33361 gctgaagaaa ctccagctcc agcaccaaaa ccagagcaac cagctgaaca accaaaacca
    33421 gcgccggctc ctcaaccagc tccagcacca aaaccagaaa aaacagatga tcaacaagct
    33481 gaagaagact atgctcgtag atcagaagaa gaatataacc gcttgcccca acagcaaccg
    33541 ccaaaagcag aaaaaccagc tccagcacca aaaccagagc aaccagttcc tgcaccaaaa
    33601 acaggctgga aacaagaaaa cggtatgtgg tacttctaca atactgatgg ttcaatggcg
    33661 acaggatg
//
LOCUS       DAVBOH010000022        33062 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOH010000022 DAVBOH010000000
VERSION     DAVBOH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.022"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ873_001116"
     CDS             complement(339..1319)
                     /locus_tag="VQ873_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3107387.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ873_001117"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ873_001117"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3107388.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ873_001118"
     CDS             complement(3669..4772)
                     /locus_tag="VQ873_001118"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3107389.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ873_001119"
     CDS             complement(4762..5130)
                     /locus_tag="VQ873_001119"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3107390.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ873_001120"
     CDS             complement(5169..6200)
                     /locus_tag="VQ873_001120"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3107391.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ873_001121"
     CDS             complement(6202..7233)
                     /locus_tag="VQ873_001121"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3107392.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ873_001122"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ873_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3107393.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10262)
                     /locus_tag="VQ873_001123"
                     /pseudo
     CDS             complement(9973..10262)
                     /locus_tag="VQ873_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10290..10922)
                     /locus_tag="VQ873_001124"
     CDS             complement(10290..10922)
                     /locus_tag="VQ873_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3107394.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10926..11567)
                     /locus_tag="VQ873_001125"
     CDS             complement(10926..11567)
                     /locus_tag="VQ873_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107395.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11560..12351)
                     /locus_tag="VQ873_001126"
     CDS             complement(11560..12351)
                     /locus_tag="VQ873_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107396.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12536..12871)
                     /locus_tag="VQ873_001127"
     CDS             complement(12536..12871)
                     /locus_tag="VQ873_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107397.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13011..13346)
                     /locus_tag="VQ873_001128"
     CDS             complement(13011..13346)
                     /locus_tag="VQ873_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107398.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ873_001129"
     CDS             complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ873_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3107399.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14761..15475)
                     /locus_tag="VQ873_001130"
                     /pseudo
     CDS             complement(14761..15475)
                     /locus_tag="VQ873_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
     gene            complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ873_001131"
     CDS             complement(15472..16368)
                     /gene="dnaI"
                     /locus_tag="VQ873_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3107400.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16369..17538)
                     /locus_tag="VQ873_001132"
     CDS             complement(16369..17538)
                     /locus_tag="VQ873_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3107401.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ873_001133"
     CDS             complement(17539..18012)
                     /gene="nrdR"
                     /locus_tag="VQ873_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3107402.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18152..18517
                     /locus_tag="VQ873_001134"
     CDS             18152..18517
                     /locus_tag="VQ873_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3107403.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18522..19217
                     /locus_tag="VQ873_001135"
     CDS             18522..19217
                     /locus_tag="VQ873_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107404.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19234..20001
                     /locus_tag="VQ873_001136"
     CDS             19234..20001
                     /locus_tag="VQ873_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107405.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20354..21553)
                     /locus_tag="VQ873_001137"
     CDS             complement(20354..21553)
                     /locus_tag="VQ873_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107406.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21550..22443)
                     /locus_tag="VQ873_001138"
     CDS             complement(21550..22443)
                     /locus_tag="VQ873_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107407.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22566..22757
                     /locus_tag="VQ873_001139"
     CDS             22566..22757
                     /locus_tag="VQ873_001139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107408.1"
                     /translation="MKIKEQTRKPAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23150..23338
                     /locus_tag="VQ873_001140"
                     /pseudo
     CDS             23150..23338
                     /locus_tag="VQ873_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23753..24370
                     /locus_tag="VQ873_001141"
     CDS             23753..24370
                     /locus_tag="VQ873_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3107409.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24413..25300)
                     /locus_tag="VQ873_001142"
     CDS             complement(24413..25300)
                     /locus_tag="VQ873_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3107410.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25449..27332)
                     /locus_tag="VQ873_001143"
     CDS             complement(25449..27332)
                     /locus_tag="VQ873_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3107411.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            27708..29162
                     /locus_tag="VQ873_001144"
     CDS             27708..29162
                     /locus_tag="VQ873_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3107412.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29143..30108
                     /locus_tag="VQ873_001145"
     CDS             29143..30108
                     /locus_tag="VQ873_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3107413.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30143..31417)
                     /locus_tag="VQ873_001146"
     CDS             complement(30143..31417)
                     /locus_tag="VQ873_001146"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3107414.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31417..32589)
                     /locus_tag="VQ873_001147"
     CDS             complement(31417..32589)
                     /locus_tag="VQ873_001147"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3107415.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32720..32968)
                     /locus_tag="VQ873_001148"
     CDS             complement(32720..32968)
                     /locus_tag="VQ873_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107416.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9693 a         7424 c         6237 g         9708 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatactttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctgg ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc cccccagaat cggactgccc caaggaagaa agaagaaagc aatccagatc
    10201 aacagaacta aaccaatata gaccttagaa tagcgtgtaa taaatgattt tagatgtgcc
    10261 ataagccatc tcctaggatt gtatatcctt tacatttgta tatgtccatt ttcgacaact
    10321 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
    10381 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac acttttctca
    10441 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
    10501 atcaaggcca ttttttgctt tgttcccaag gataaatgcc ggtattcaac gtcttcaaat
    10561 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
    10621 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
    10681 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta tcccgtaaac tttaccatct
    10741 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
    10801 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
    10861 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
    10921 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa gaatcaacat aactaataag
    10981 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
    11041 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
    11101 gacagtagta agtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
    11161 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
    11221 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
    11281 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
    11341 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
    11401 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
    11461 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    11521 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    11581 tttaagtacc atataaggga caacataaag gatataagga gtaaagagtt tcatcaaact
    11641 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    11701 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    11761 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    11821 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    11881 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    11941 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    12001 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    12061 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    12121 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    12181 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    12241 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    12301 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    12361 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    12421 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    12481 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    12541 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    12601 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    12661 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    12721 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    12781 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggca
    12841 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    12901 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    12961 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    13021 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    13081 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    13141 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    13201 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    13261 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    13321 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tcctcctttt gatagcgttt
    13381 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    13441 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    13501 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    13561 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    13621 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    13681 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    13741 agacgttgct tagtcaaagc tgatacaaaa ataatcggtg cataaggcag gtattggaac
    13801 tgctcacgga tatcttcttc ccagtttttc atggtatggt tgtctttttc aagcgtatcc
    13861 cacttgttga ctacgataat cattccttta ccagcttcat gggcaaatcc tgcgatacgc
    13921 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    13981 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    14041 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    14101 tgggtatcaa tagcgtcacg agttgttcca gcaacaggac tggcaatgac acggtcttct
    14161 cccaagatag cattaatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    14221 ttaatgacat ctggattttc ttcttcatat tcatttggaa ggttttccac aatcgcatct
    14281 agtacatccc ctgtaccgat accatggaca gatgagatag gcagtggttc acccaaaccg
    14341 agagcataga aatcatagat atcatttctc atctcagggt tatccacctt gttgactgcg
    14401 aggataactg gtttgtgggt cttataaagc ttgcgggcta cgtattcgtc tgcatcggta
    14461 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    14521 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    14581 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    14641 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    14701 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    14761 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    14821 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc ccccccagca tagtcagcct
    14881 gcacacggtc ataagcttgg attgtctcag ttgactgttc ttggtattct tcctcaaaga
    14941 caacattctc tagtggcagt ctcggtttca catcatgatg ttgatttggc acacccagtg
    15001 ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa gagctctgcc acttcttcag
    15061 acttgtatcg aaccaaaccg ataatcacac caccatagcc caagctttca gctgccaaca
    15121 aggcgttttg tccagcaaga gctgcatcga ccgaactaat caagagacct tccacacctt
    15181 ggggttggaa ggtgtcggta tgaagtcggg ctcccttttc tgctcggttc aaatctccga
    15241 caaagagaag gaaaacagca gactggcgaa tggcttcttg aggtaccaat tcatacaagg
    15301 catctttctt ctcttgactt cgtaccacaa tcacagagta ggattggaaa ttcttccaag
    15361 atgatgccat ctgggctgct gtcaaaatct catttaagtc tacttgggga atttcttgct
    15421 ctttaaacct gcgcactgaa gtatgagcct tcatcaattt aatggtttct gtcatcgacg
    15481 gtttactcct tctaaacgag tctcctcagc caaataacgg atgcgttcca tgacccgtct
    15541 ggcttcccag gtttcgtcat ttccatgttt cactttcgca aaatgcttct ccaaatcttc
    15601 aaagttgaag ttggatgtga aaaaggtcgg taaattttcc tgcatccgat attggagaat
    15661 gacctgcagg atttcgtcac gtacccaaac ggttgattgc tcggcgccaa tatcatctaa
    15721 aatcaggacc tcagacagct taatctcatc caccaaggtc ttaacattgc catcactgat
    15781 agcatttttg acatcaatga caaagctagg atagtggagg agagttgatg aaacaccacg
    15841 tttttctgat aaatcatgag ctaaggccgc caccatgaaa cttttaccca caccaaagtc
    15901 tccatataag taaagacctt ttcgaatagc tggatattgc tccacgaagg ctagtagctt
    15961 ttcaaaaact ggtaagcgcc ccaaatcatc caagtcaact tgagccaaac tagctttctt
    16021 gagactggct ggtagattga ttaacttgag acggttctta atagccgctt ctttttcagc
    16081 cgcgattagc tcaggagttt cttcatatga aacatctgca tagccatgat tcttaaccaa
    16141 aatcggcttg tagcctttgg caatataatc cgtatcccca cggagaaact tgtcacgctc
    16201 ggtgatgtac tgattaaact tggagatact gcgatttaat tcctctggag tcaaggattc
    16261 ttgctggata aaagccgcaa catcagggtc cttcatgatt ttctggacca aatcttgata
    16321 ataaaaacgg ctgggttgac gtttgagtac gtctccgaca ctttccatct aatctcctcc
    16381 tttttctaat cgagctaata gttcttgctt cttacgttct agttccagac gagtttcctc
    16441 gctggtttca ttcttatatt caggattact ccatttagga acattggttt ttactggggc
    16501 agtctgattc tgtttttgtg tttttgcttt ctgtcctcgc tcacggatgc gcaagactgc
    16561 cttttctgcc gaatgaatct tttgataggc atagtcattg gctaccttca tggcatattt
    16621 ctcattgata tttgccgaat cgaccttatt aaaggtcaat aaaagaatga tattgatgac
    16681 ttcgtccagc aagcccaagc cagccatctg ttgcaagagt tctctttctg tttgggtaat
    16741 ggttcccttg cgtgtttgct tgatttctgc caagaactgc agggcagttt tacttttggc
    16801 ttctttgata atggttgttt ccttaagact aaagtcagag gaaactggtt tttgagcaat
    16861 tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca gctgttgact tggccaattg
    16921 ataggtttca aaccaagtcc atttcttctc ctcggcaata gcaaagaggt ttaagacatc
    16981 ggactgctca tccgcaaaac gaagtccatc tcgagccatc agctggcgaa aatgttccaa
    17041 gtcaaaatca ttggccactt tcttcttgag accaaggtct tcttgactgc ctagttctgc
    17101 caattctgga aagacttgat tgagtgagac aggtatttct tcaccatcag cactttcaac
    17161 tttcaaatcc tccacagcag agtcgccaat ctttttctct aagagtctgc gataaacagg
    17221 atgctccaag aagtcttgac tagatagagg agcatggagg gctagctgat aaacatcccc
    17281 cttttgatag agggtcaaga gattaaaagc agataagatt ttcaatgatt ttatcagtct
    17341 atccatccca aagttgagat gattgaggat acttgaaaaa agatattcct ttctaccatt
    17401 atcccaaaaa ctgattgtat aaagataaag gctcagtgcc tcctgaccga taatcgggag
    17461 gtagcactgt accagagatg aggtatcttg cgacacccga ttattcttta gataagaaaa
    17521 acggtcaatt ggcttcattt atctttcctt tttcttttta gaggactggg tgatttgttg
    17581 gagcaagctc tctaactcac tgacatcctt aaaactacga tagacactag caaaacgtac
    17641 ataggtaatc tcgtccaatt cagccaactc ctccatgacg agtgaaccaa tgtcctcact
    17701 ttgaatttca ttttcatttc gaccacggag tttctgttcg atacgattga ctaccatgtt
    17761 gatttcatca cttgacacag gacgtttctg ggctgagcgg ataatcccat taaagatttt
    17821 atctctggag aattgttccc gtgtaccatc ttttttaaca accactaagg ttctttcttc
    17881 tactcgttcg taggttgtaa aacggtgttg gcattcgtcg cactcacgtc ttctacgaat
    17941 ggtgttccct tcttctgctt ggcgactatc gataacactt gacttggtag ccccacattt
    18001 tggacaacgc atcctttccc tccttatcgt tttcttttca ttataccatt ttttaagcga
    18061 ttcccaaaac aattcttctt tttgcttgac aagttttttg ttttgttgta ttatttaatt
    18121 aagacaaaag gataagagaa aggagactaa gatgtcctgg acatttgaca acaaaaaacc
    18181 catctattta cagattatgg agaaaatcaa gcttcagatt gtttcccata cactggaacc
    18241 caatcaacaa cttccaaccg tgagggagct agctagcgag gctggtgtca atcccaatac
    18301 catccaaaga gccttatcag accttgaacg agaaggattt gtctacagca agcgaacaac
    18361 tggacgattt gtgactaagg ataaggagct aatcgcccag tcacgcaaac aattatcaga
    18421 agaagaattg gaacacttcg tttcctccat gacccatttt ggctatgaaa aagaagaact
    18481 accaggcgta gtcagtgatt atattaaagg agtttaagcc tatgtcatta ctagtatttg
    18541 aaaatgtatc caaatcatat ggagcaacac cagcccttga aaatgtttct cttgacattc
    18601 cagctggaaa aattgtcggc cttcttgggc caaacggctc aggaaaaaca accctgatta
    18661 aactaattaa tggcctctta caaccagatc aaggacgtgt cctcatcaac gacatggacc
    18721 caagcccagc aaccaaggcc gttgtagctt atttgcctga tacgacctat ctcaatgagc
    18781 aaatgaaggt caaagaagcc ctaacctact tcaagacctt ctataaagat ttcaatcttg
    18841 aacgcgccca tcatctactt gcagacctgg gcattgatga aaatagtcgt ctcaagaaac
    18901 tatcaaaagg aaacaaagaa aaggttcaac tgattttggt tatgagccgt gatgctcgtc
    18961 tctatgtttt ggacgaaccc attggtgggg tggatccagc agcccgtgct tatatcctca
    19021 ataccattat caacaactac tcaccaactt ctaccgtttt gatttctacc cacttgattt
    19081 ctgatatcga gccaatcttg gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc
    19141 aaggaaatgt agatgatatt cgctacgagt caggtgaatc cattgaccaa ctcttccgtc
    19201 aggaatttaa ggcctaagca aaggagatta tttatgtttt ggaatttagt tcgctacgaa
    19261 tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt cctttctgcc
    19321 ctcatcggaa tacagacaca aggctttaaa aatctacctt accaagaaag tcaggctact
    19381 atgctacttt ttctagctac agtctttggt ggcttgatgc ttacacttgg gatttcaacc
    19441 attttcttga ttattaaacg cttcaaaggt agtgtctacg accgacaagg ctatctgact
    19501 ttgaccttgc cagtttctga acaccatatc atcacagcca aactaatcgg tgcctttatc
    19561 tggtcattga ttagcaccgc tgtattggct ctaagtgctg ttattattct ggctttaaca
    19621 gctccagaat ggattcctct ttcttatgtg attacatttg tagaaacaca tcttcctcag
    19681 atctttctta caggtatatc cttcctacta aatactattt caggaatcct ctgcatctac
    19741 ctggctattt ccattggaca gcttttcaat gaataccgta cagcactcgc tgttgcagtc
    19801 tacattggta tccaaatcgt cattggattt attgaacttt tcttcaatct tagttctaat
    19861 ttctatgtca attcactggt aggactcaat gaccatttct atatgggagc aggtatagcc
    19921 attgttgaag aactcatatt catagctatc ttttatctcg gaacctacta catcttgaga
    19981 aataaggtta atttgcttta aataattttt acctagatat gtaacatact catagaacaa
    20041 aagagaccag gcaaaaagtc tttacaatta gaaaacgcat agtatcaagt gttaaaaatc
    20101 cttgatatta tgcgtttttt gtgagctgac ttatttcctt tcactatatc gcaaaatgaa
    20161 ataagaacgg aacgatggga ttttggaatt caaatcaatt tataagaatg ttttagaagt
    20221 aatattatcc tattccagat tcagttcact atacaattga gttttcaagc aacctgttta
    20281 cataatgtgt acataattag gttcgtgatt ccaccctttt cacctttaaa aacctcgctt
    20341 tcgcaaggct cttctattta taagataagg cacgtttaaa ggttttccaa atccctaaat
    20401 catccgtttg aagaacgaga ctagcataca tgcgtccgat aaatcctgtt gctaccaccg
    20461 caaaaatcac tgtaatagca agtgaaatcc atgcttccgc tccctccgca tagccattaa
    20521 tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat ataagaacca atcttcaaga
    20581 ggagattgtc accagctgca cctagagctg tcactccaaa aaaaccaccc ataatcaaaa
    20641 tcatcaaagg cgacaaggct ttccctgagt cttcaggacg agaaaccata gatcctagga
    20701 aggctgccaa gactacgtac atgaaaagac tgatcaaaat aaagagcaag gtattcagtg
    20761 agatagcatc tcccaagtga tccaaaatac cagactgagc caagaatggc aaatctttaa
    20821 agagcaaaac ggcagccaga ccacctacaa catagatccc aatatgcgtt aaaatcacta
    20881 gaaacagagc catcatccgc gcatagaaat agtgacttgc ccttatgcta gaaaagacga
    20941 cttccataat tttggtgcct ttttcactgg caacttcctg agctgttaca cccgcatagg
    21001 taatcagaat catataaaga aagaatccta aggcacctgc tgcaattgtt tgaataaact
    21061 ttttattttc cttggcttca tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt
    21121 tttcctgctc ttgagacaag gaagcagttg aacgattaag ctgattttgc agttcattga
    21181 gtgtacctgt aacctcaaat ttaattccat tttcaagcga tgtttcgcca tgataaactg
    21241 cctttagaac actatcttct tgatcaatgg tcaaataacc ttttaatttt tcttctttaa
    21301 ttgcttcttt ggcacttgct tcgtctttat agtcgaagtt aacaccattt acattcttca
    21361 gtccttctgc tacagatggc actgttgtca ctactgccac tttattattt ttagccatag
    21421 aagaaccttg gagatgccca attcctacag agattcctaa aaagaggaac ggcgaaatca
    21481 ccataaagaa gaaactccat gactcgacat gtcgaagata ggtttccttg attacaaccc
    21541 acatatttct catacttcca ctcctgattc tagtttaaag atttcatcga tagttggcgc
    21601 ttgttggtca aatgttgcga tatattgacc ttgagtcaag attgggaaga gttcccttcc
    21661 agcgctctca tcctccaaaa tcaatttcca actgccttgt ttggtcaagc tcacctgttt
    21721 gacatgagga agattttcca attcttcctt gcttcgttca cttgaaacaa agagacgcgt
    21781 tttcccgtat tgattgcgga catcctgaac tggtccgtgc aagaccacac ggccatctcg
    21841 aatcatcaga atatcgtcac aaagttcctc aacattggtc atgacatggt cagaaaagat
    21901 aatggttgct ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac
    21961 tgggtccaat ccactaaaag gctcatccaa gataatcagg tctggttcat gaatcagagt
    22021 aataatgagc tgaatcttct gctgatttcc ttttgacaga ctcttgattt tatctgtcag
    22081 ctttcctttt acttccaacc tcttcatcca ttgagggagt ttttctttga cttctttggc
    22141 atccatgcct tttagagtcg ccaagtagcg aacttgttca agaactgtca atttaggcat
    22201 gagactgcgt tcttcaggca gataaccaat ccgagcatag atctcctgac gaatatcctg
    22261 accatccaga ccgatttctc cctgatattc taggaatttt aaaatactat ggaaaatcgt
    22321 tgtttttcca gcaccatttt ttccgactag tcccaaaata cgacctggtc gcgcttgaaa
    22381 gtcaatacca aacaaaactt gcttggatcc aaaacttttc tctagacttc ttacttctag
    22441 catctttcac ctccgaaatt tcttgcactc attatactcc tttttgatag cctttacaat
    22501 gttttttgtc catttttaga agactattgc tgtgtaaaat atggcctgga gcacttttat
    22561 actcaatgaa aatcaaagag caaactagga agccagccgt agactgctca aagtacagct
    22621 ttgaggttgc agataaaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
    22681 gaactgacga agtcagtaac tatatctacg gcaaggcgaa gctgacgtgg tttgaagaga
    22741 ttttcgaaga gtattagtga taaatccatt atacagcagc aaacttaatt tataccttcc
    22801 gctcctcaac tgtctatttt taatcctgaa ttgttatttg agtaactcct ttttcctcgt
    22861 aaagttttct tcctctaaaa cttctggaaa aaggctaata gtttcagaca acatttttat
    22921 aagaaacaag ttcatctgtc atttcaagaa ggagtaatcc tttatctact aatggacgga
    22981 acagaattca accgcttgtc ccatatgttt tctaaggatt atatagtaaa atgaaataag
    23041 aacaggacaa attgatcagg acagtcaaat tgatttctaa caatgtttta gaagtagatg
    23101 tatactattc tagtttcaat ctgctatatc tattatgcac acccctatag gatctaatga
    23161 aaatcacaac aggctcattc atagatagtt acctcaggaa actaagaaaa cgactacaaa
    23221 ggaagtcgca ttcatcgaaa agtggattaa caactatcct aaaaaatgct tgaactacaa
    23281 gtcccccaga gaagacttct ggatgactaa cttgaacttg aaatttagca ataattaatt
    23341 caccatctaa ctatatttag taattatttc agaactgatt aatattaaaa ttaactaaca
    23401 attcaaagga ttcatactag ccataaatta cgtccatcag agagagactc ttactacttt
    23461 tagattttag tctttctagc ttcagaatac atctaaactt tagggaaaat gactattcga
    23521 aagcgcgaat gcctcaaaat tatctcagat aagctattcg aaacttagaa tgcttttaaa
    23581 tttatggaat tgcgattatt tgaaacctag aatgcatata acctttagtt gacagaccta
    23641 ttctaagtct cgaagggcta tttactttct attccttatc aaaaaagact cattccccct
    23701 ttctcctcca aaatatggta tagtagaaat atactatcta tgaggagttt acatgtcaca
    23761 ggataaacaa atgaaagctg tttctcccct tttgcagcga gttatcaata tctcatcgat
    23821 tgtcggtggg gttgggagtt tgattttctg tatttgggct tatcaggctg ggattttaca
    23881 atccaaggaa accctctctg cctttatcca gcaggcaggc atctggggtc cacctctctt
    23941 tatcttttta cagattttac agactgtcgt ccctatcatt ccaggggcct tgacctcggt
    24001 ggctggggtc tttatctacg ggcacatcat cgggactatc tacaactata tcggcatcgt
    24061 gattggctgt gccattatct tttatctagt gcgcctatac ggagctgcct ttgtccagtc
    24121 tgtcgtcagc aagcgcacct acgacaagta catcggctgg ctagataagg gcaatcgttt
    24181 tgaccgcttc tttattttta tgatgatttg gcccattagc ccagctgact ttctctgtat
    24241 gctggctgcc ctgaccaaga tgagtttcaa gcgctacatg accatcatca ttctgaccaa
    24301 accctttacc ctcgtggttt atacctacgg tctgacctat attattgact ttttctggca
    24361 aatgctttga cacgtaaaaa atccgtttgg tttcccaagc ggattttgtg ctttattttg
    24421 aaacttcttt tgcaagaaca aagttcccaa gtgtggcaga accatttcct gcgactgctg
    24481 gcgtcacgat atagtcacgc acatctggta ctggtaggta accattaaga agagatgtaa
    24541 atttctcacg gacacggtcc agcatatgtt gttgagccat gacccctcca ccaaagacaa
    24601 tcacgtctgg gcggaaagtc actgtcgcat taaccgcagc ttgagcgata tagtaggctt
    24661 gaacatccca aacagggttg ttgagttcaa tagtttcccc acgtacacct gtacgagctt
    24721 ccaaacttgg accagctgca tagccttcca gacatccctt atggaaagga caaacaccct
    24781 taaactcttt ttcaatatcc attgggtgtc tagcaacata ataatgaccc atttcagggt
    24841 gacccacacc accgataaac tcaccacgtt ggatgacgcc tgcaccgata cctgtaccga
    24901 ttgtgtagta aaccaagttt tcgatacgac caccagcatt gttacgggca accacttcac
    24961 cgtaagcaga gctgtttacg tctgttgtga agtacattgg cacgtttagg gcgcgacgaa
    25021 gggcaccaag caagtccaca tttgcccagt ttggttttgg agtcgtcgtg ataaagccat
    25081 aagtttttga gtttttgtca atatcaatcg gcccaaatga accaactgca agaccagcaa
    25141 ggttatcgaa ttttgagaag aactcaatgg ttttatcgat tgtttcgatt ggagttgttg
    25201 ttggaaattg tgttttttct acaacgttaa agttttcatc accaacagca cagacaaact
    25261 ttgtaccgcc agcttccaag cttccatata attttgtcat gataaacctc ttgtttttat
    25321 tttctttatt atagcatact tcgaaagtct aaatgtctct attttttaga ttttcctctg
    25381 taaatcttac tatctaataa aaacgaacaa acatgtcatt tgttcgtttt cacattagag
    25441 aggattgatt agattttcac ttcgatcaca gcatccccct tcgcaactga acctgttgcg
    25501 actggagcta ctgaagcgta gtcagctgta tttgtaacga taaccattgt tgtatcatca
    25561 agtccagctg tagcgatttt atttgagtca aatgttccaa gaacatcgcc aactttcacc
    25621 ttatcacctt gagcaacttt tgcttcaaaa ccgtcaccgt tcatagatac agtgtcaata
    25681 ccaacatgaa tcaaaacttc agcaccattt cttgttttca aaccaaaagc gtgccctgtt
    25741 ggaaaggcaa ttgaaacttc agcatcagct ggtgcataga ccacgccttg gcttggtttc
    25801 acagcgatac cttgtcccat agctccactt gagaagactg ggtcattgac atcagcaaga
    25861 gcgacaacat caccgacgat aggagttaca agtgtttcat tttgaagagc tgctggcgca
    25921 acttcttctt tttcttcagc cacttcagct tgttttgcag ctgcagttgc gtctacttca
    25981 tcttcgtaac caaacatgta agtaagagca aaaccaaggg caaatgatac agctaccata
    26041 agaaggtatt gtggaagttg tccgttacca acataaagca ttgtaccagg gatgatggtg
    26101 ataccattac cagtaccagc aagtccaagg atagaagcca atccaccacc gattgcacca
    26161 gcaatcaatg aaaggaagaa tggtttacgg aagcgcaagt tcaccccgaa gatagcaggc
    26221 tctgtaatac ctaggaaggc agaaagagca gccgggaaag caagtgtttt cagttttgga
    26281 ttttttgttt taacaccaac cgcaacagta gcagcacctt gagctgtcat agcagctgtg
    26341 atgatagcgt tgaatgggtt agcatggtca gcagcaagta attgcacttc aagcaagttg
    26401 aagatgtggt gcacacctga cacgacgatc aattggtgaa ccccaccaat caagaaacca
    26461 ccaagaccaa atggcatgct aagaatcgct tttgtagcaa taaggatgta gttttcaaca
    26521 acgtggaaaa ctggtccaat gacaaagagt ccaaggatag acatgaccaa aagtgtcacg
    26581 aatggtgtta ccaagaggtc aatgacatct ggaacaacct tgcggacagc tttttcaaat
    26641 ttagctccga caaccccgat gatgaaggct ggaagaacgg aaccttgcaa accaacaaca
    26701 gggatgaaac caaaaaagtt catcgctgtt acttcaccac cttgagcaac tgcccaagcg
    26761 tttggaagtg agccagagac aagcatcata ccaagaacga taccaacggc aggatttcca
    26821 ccaaatacac ggaaggttga ccacacaacc aaacctggca agatgatgaa ggctgtatct
    26881 gtcaagattt gtgtgtaagt tgcaaagtca cctggaagtg gcatttcaag agcgttgaaa
    26941 agaccacgca cacccatgaa gagacctgtc gctacgataa ctgggatgat tggaacgaaa
    27001 acatcaccaa aagtacggat agcacgttgg aaccagttcc cttgtttagc aacttctgct
    27061 ttcatgtcat ccttagatga tgttggtaat ccaagtacaa caacttcatc gtacattttg
    27121 ttaactgtac ctgtaccaaa gataatttgg tattgccctg agttaaagaa agcaccttga
    27181 actttttcca agttctcaat cacttcttta ttgattttct cttcatcttt gaccatgaca
    27241 cgtagacgag tcgcacagtg ggcaacacta ttgacatttt cacgtccgcc caaggcatcg
    27301 atgacttttt ttgcaatttc ctgattgttc atttgcaaaa atctccttat ataacatttt
    27361 gttcttgttt gaaagcgatt ttattcgccc ttacgactat tattttatca tgttttaaaa
    27421 atatgtcaag cgttttgcat aaaaatattc tatccactta gtgggcaagc tttagattga
    27481 ttgtttttga ctgtttcatc aggaattcct tgaaaaataa gtttgaaacc ttggttaaaa
    27541 agtattttat ttcattatct ttcacatttt cgtaaaaatt tgattgattt cctgtattta
    27601 ttttatgata atcgtttgac agtttttcct cttttttaac ataaaaggct tgcatttttt
    27661 atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg gaatggacaa
    27721 ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa catataaagg
    27781 aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa acaggacttc
    27841 tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt taccagaatt
    27901 ttccttttgg tgcagcccac ggtttgaaat cttgggcaca gctagaaagt gatgatttgg
    27961 ttcactttaa agaaactgga atcaaagttt taccagatac tccattagat agccacggtg
    28021 cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat acaggaaatg
    28081 ttcgcgatga aaactggatc cgtcacccat accagatcgg tgctttgatg gacaaggagg
    28141 gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct actgaccact
    28201 tccgcgatcc acaaattttt aactttaaag gtcaatacta tgctgtcgtc ggtggacagg
    28261 acttggagaa aaaaggcttc gtccgtctct acaaggctgt caataacgac tacacaaact
    28321 ggcaagcagt tggcgacctt gactttgcta acgaccgtac tgcctacatg atggaatgtc
    28381 ctaatctgat ctttgtagag gaacagcctg tccttctcta ctgtccacaa ggattggata
    28441 agaaagttct agactacgat aatatctttc caaatatgta taagattggg gcttcctttg
    28501 accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat tacggtttcg
    28561 aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca gttagctggc
    28621 ttggtttgcc agatgtttct tacccatctg actgttttga tcaccaagga accttctctt
    28681 tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc gctgctatta
    28741 aggaccttcg tgcttctgaa gaagccttct caaaccgttc ccaaaccaag aacacttacg
    28801 aacttgaact caacttggaa gctaatagcc agagcgagat tgtcttactt gctgataaag
    28861 aaggtaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca gtggatcgta
    28921 gccaggctgg agaacagtat gcccaagaat ttgggacaac tcgttcttgc cctatcgaga
    28981 atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt ttcatcaata
    29041 aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat ggtatcctga
    29101 tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc aaaactaact
    29161 gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat caataaaaaa
    29221 gggtatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgagaga attaagctat
    29281 aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat cggcttgatt
    29341 ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga acaccaactc
    29401 ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga gaaggaacgc
    29461 gaatacatcg aaatgttgga agccaatcag gtagacggca tcatttctgg tagtcacaac
    29521 ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga ccgaaaccta
    29581 tcgccagaca tccctgttgt ctcctctgac aactatgctg gtggggttct tgctgcccaa
    29641 accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga caattccaat
    29701 tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc tcctattatc
    29761 aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa tatcttgacc
    29821 cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct gatcattaaa
    29881 atcgctcaag aattgggcat ttctgtccca aaagagctca aggttatcgg ctatgatggg
    29941 acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc tttggaagag
    30001 attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga agtcgccaca
    30061 actggttact tcttaccagt tacactatta ccaggaaaaa gtatttaaac acaagaaaac
    30121 tcagaccgat tcgtctgagt ttttatgatc ttaaattttc gagatagcgc tgggctgtct
    30181 ctaggttaaa ggttttatct gagatgaggc gctctactag gggagcaact tcagattcac
    30241 tagccccagc taggagagct agggatttgg cctgtagttt catgtggcct tgctggatgc
    30301 ccgtacttac caaggctttg agggctgcaa aattttgggc aagaccgatg gacacgataa
    30361 tctgggctaa ttctctggca gaaggatttc ctagtagatc atgactgaga gctacacgtg
    30421 ggttgaggcc gatagagcca cccttagtcg ctacaggcat gggcagggtc atctcaccga
    30481 ccaattcttc tctttcaagg tccagcgtcc agcaactaag accttgatag cgtccatctc
    30541 gactggcaaa ggcatgggcc ccagcttcga tggcacgcca gtcattacca gtggcaatca
    30601 aaatcgcatc aataccatta aaaattcctt tattatgagt agcagctcgg taaggatcag
    30661 cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat ctctcgtcct tgatcctttt
    30721 ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt caccagagaa tcggtcgcgt
    30781 agttggacag gattcccatg agactctgtc cctgactgag ttcttctaag actggtttca
    30841 aggcttccag catggtgttg agcatattgg cacccatggc ttcctgggta tcgacatgaa
    30901 tataaacaac gagaaagtct ggttcgcctt ttatctgctc gacatgcaga tcacgcgccc
    30961 cacctccacg tttaacgata gaaggatagg cttgattggc aagctccaag agctccgctt
    31021 tcttgctggc aatcttctct tgcgctagtt taggattagc aacttgataa agggctacct
    31081 gcccaatcat ctgtcgctga tggacttgtg cagtaaaacc acctgcacgc ttgatgattt
    31141 tgctggcata gctggccgcc gcaaccacag agggttcttc tgtcacatag ggaacggtgt
    31201 attcctgacc gttgacaagt acctccggaa ccagtgaata aggcagagaa aaagttccca
    31261 ctacattctc actcagctgg tctgccacag tcacgctcat ctgttcatcc ttctccagac
    31321 tagcttgtct ctcaggacta aggagcgcct gagcttttaa cagctcgagg cgctcttggt
    31381 atgatttttt agaaaatcca ttccaactta tcttcattat ttttcaacct tgctataacg
    31441 gcgttggtgg tcgagaattt caaccaaggc aaaatcttga ttttcatagc cagcaaactg
    31501 ggcagagttt gtttcatcca agtttacttc ctcaaaaaag accttttcat agtctgcaac
    31561 ggataagaca gttcgttggt tgagcttgtt caagcggtct ttatccaaat aagcttcata
    31621 tccttcaacc aattcaccac tgaagaactc agccacagct ccacttccgt aactataaag
    31681 ggcgatttta tccccagctt tcaagctatc tgtattttcc aagagagaca aaagtccaag
    31741 gaaaagtgaa cctgtgtaga tattccccac cttttgactg tagagaatag actggtcaaa
    31801 atgcttttgt aagaggtctt ttttctcttg aggcaggctc ttatccatga tttttttcaa
    31861 gccttttagc gctaatttag gataaggcaa gtggaaacaa acagccgcaa aatcatccaa
    31921 agtaagctgg tagcgttttt gatattcaag ccaagtcgtt ttcaaactat ccaagtattg
    31981 ttgggtagaa tagacaccat ttacataagg agttgtcgag taatttggtc gccagaaatc
    32041 catgatgtca cgggtctgag ctacattgtc attattaaag gccatcatgc gtggattttg
    32101 tgtaatcaac atagccacac ttccggcacc ctgagtgggt tctcccggag tttcaatacc
    32161 gtatttggca atatcacttg caatgaccaa gaccttggac tccggagaat tttccacatg
    32221 caatttggca taatggaggg cagcagtcgc cccatagcag gcttctttaa tctcgaaact
    32281 acgagcaaag ggctggatgc ccagcaagcc atgcacaaag acggccgcag ccttactctg
    32341 gtcaattcct gactcggtcg ccacaatgac catgtcaact tcttgtcttt cttgctcagt
    32401 taaaatagag tcactagcac tggccgccaa ggtcacgatg tcctcagtta ggggcgcaat
    32461 actcaattcc ttgagtaaga gtcctttact taatttttca gggtcaattc ccctcgcttc
    32521 tgctaagtct tgtaatttca agacatattg actggtcgca aaaccaatct tatcaatacc
    32581 gattgtcata tttacctctg ttttatcatt catgtaaaaa atcgttctat actattttat
    32641 cacaaatggc agtaaaagag agaaaaaaga cttgattcac caaatcaagc ctcttattgg
    32701 tcatcatttt aaagaatgat tagttgctag agagttcacc gatataagta gctttataag
    32761 ctccattcac agttatcagc tcctggagga tcaaatttcc tgagtaagtc cttcccatct
    32821 catctacaaa tttttgataa aactgactgg tcggaatttc tctgacatcc ttatcaaatg
    32881 tcttatcaag tgttttacta accttctcag caatcaattg atgctcttgc catccacttt
    32941 gaaactctga gcccgaacta gaaaccatga ctgggataaa caacaaggtc agtagattta
    33001 cagacaataa ggaaagtagt agacttcctg caaaactaga atcctagttc atgattgata
    33061 at
//
LOCUS       DAVBOH010000023        32119 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOH010000023 DAVBOH010000000
VERSION     DAVBOH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.023"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ873_001149"
     CDS             complement(181..1359)
                     /locus_tag="VQ873_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3107417.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ873_001150"
     CDS             1639..2901
                     /locus_tag="VQ873_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3107418.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ873_001151"
     CDS             2904..3800
                     /locus_tag="VQ873_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3107419.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ873_001152"
     CDS             3815..4132
                     /locus_tag="VQ873_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3107420.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ873_001153"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ873_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ873_001154"
     CDS             4475..5077
                     /locus_tag="VQ873_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3107421.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ873_001155"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ873_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ873_001156"
     CDS             5624..6394
                     /locus_tag="VQ873_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3107422.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ873_001157"
     CDS             complement(6672..6959)
                     /locus_tag="VQ873_001157"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3107423.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ873_001158"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ873_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ873_001159"
     CDS             complement(7545..7748)
                     /locus_tag="VQ873_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3107424.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ873_001160"
     CDS             complement(7779..8387)
                     /locus_tag="VQ873_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3107425.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ873_001161"
     CDS             complement(8426..8596)
                     /locus_tag="VQ873_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3107426.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ873_001162"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ873_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3107427.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ873_001163"
     CDS             complement(9258..9422)
                     /locus_tag="VQ873_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3107428.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ873_001164"
     CDS             9865..11346
                     /locus_tag="VQ873_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3107429.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ873_001165"
     CDS             11708..12703
                     /locus_tag="VQ873_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3107430.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ873_001166"
     CDS             12830..14140
                     /locus_tag="VQ873_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3107431.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ873_001167"
     CDS             14236..15138
                     /locus_tag="VQ873_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3107432.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ873_001168"
     CDS             15140..15985
                     /locus_tag="VQ873_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3107433.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ873_001169"
     CDS             15995..17314
                     /locus_tag="VQ873_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3107434.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ873_001170"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ873_001170"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ873_001171"
     CDS             complement(17861..19132)
                     /locus_tag="VQ873_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3107435.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ873_001172"
     CDS             19402..19641
                     /locus_tag="VQ873_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107436.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19806..20003
                     /locus_tag="VQ873_001173"
     CDS             19806..20003
                     /locus_tag="VQ873_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107437.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTHWKNRYE"
     gene            20122..20300
                     /locus_tag="VQ873_001174"
                     /pseudo
     CDS             20122..20300
                     /locus_tag="VQ873_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20337..20789
                     /locus_tag="VQ873_001175"
     CDS             20337..20789
                     /locus_tag="VQ873_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3107438.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21080..21550
                     /locus_tag="VQ873_001176"
     CDS             21080..21550
                     /locus_tag="VQ873_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3107439.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            21569..22657
                     /locus_tag="VQ873_001177"
     CDS             21569..22657
                     /locus_tag="VQ873_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3107440.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLLGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22638..23066
                     /locus_tag="VQ873_001178"
     CDS             22638..23066
                     /locus_tag="VQ873_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3107441.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23201..24154
                     /locus_tag="VQ873_001179"
     CDS             23201..24154
                     /locus_tag="VQ873_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3107442.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24156..24899
                     /locus_tag="VQ873_001180"
     CDS             24156..24899
                     /locus_tag="VQ873_001180"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3107443.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24910..26706
                     /gene="pepF"
                     /locus_tag="VQ873_001181"
     CDS             24910..26706
                     /gene="pepF"
                     /locus_tag="VQ873_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3107444.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26766..27443)
                     /locus_tag="VQ873_001182"
     CDS             complement(26766..27443)
                     /locus_tag="VQ873_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3107445.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27690..28460
                     /locus_tag="VQ873_001183"
     CDS             27690..28460
                     /locus_tag="VQ873_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107446.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28453..29217
                     /locus_tag="VQ873_001184"
     CDS             28453..29217
                     /locus_tag="VQ873_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107447.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29641..30432
                     /locus_tag="VQ873_001185"
     CDS             29641..30432
                     /locus_tag="VQ873_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3107448.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30543..31211
                     /locus_tag="VQ873_001186"
     CDS             30543..31211
                     /locus_tag="VQ873_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3107449.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ873_001187"
     CDS             complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ873_001187"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3107450.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         9731 a         5259 c         6723 g        10406 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagctgcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aatcatactc aatgaaaatc
    19741 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac
    19801 gtggtttgaa tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata
    19861 gagtacgcag tgttcctatg attcattcaa ctccgcctca atctgtctta gatcgagata
    19921 cttttacaat tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc
    19981 attggaaaaa taggtatgaa taaattggct tcccttagaa ccacatctag gggcttttat
    20041 gtataataga ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg
    20101 ttgtcaggag gtaaaagcgc tatgcctatg acacaaaaag agatggttaa actccttacg
    20161 gcccatggtt gataaagact agaggcggta aaggttccca tattaaaatc gagaagcaag
    20221 gggaaagacc tatcacaatc cctcatggtg agctgaataa gtacactgaa agagggataa
    20281 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    20341 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    20401 ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt tctgaggctt
    20461 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    20521 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    20581 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    20641 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    20701 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    20761 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    20821 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    20881 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    20941 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    21001 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    21061 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag aggaagagtt
    21121 ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc atgcggtaga
    21181 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    21241 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    21301 gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta aaaaaggatt
    21361 ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg aggttgggct
    21421 agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta tggaatggaa
    21481 tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt atccttatcc
    21541 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    21601 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    21661 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    21721 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    21781 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    21841 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    21901 aagcgatcaa agaatcatcc tgatgctttt aggaggcttg atggttcatc tcggcttgat
    21961 attattggcg atagtgtttg gctttttgac aagaagctgg tattttgcag ggacttggat
    22021 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    22081 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    22141 acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact ttgttcaagc
    22201 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    22261 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    22321 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    22381 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    22441 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    22501 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    22561 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    22621 gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc aagattgccc
    22681 tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat atcccttgtc
    22741 ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct tttgaatgcg
    22801 ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt ctgctttgga
    22861 gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg gttggtcagc
    22921 taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc tatcagctga
    22981 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    23041 aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct aaactgaacc
    23101 cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc ttcagagaat
    23161 ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa catggcaaga
    23221 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    23281 gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg ttgaccgctt
    23341 cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag cctactaccc
    23401 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat cagaattgac
    23461 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    23521 ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    23581 tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc tggatcctgg
    23641 catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg ccttggaaca
    23701 ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg ttctctctat
    23761 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcagt
    23821 tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc atgtagcggc
    23881 aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa acatcttggc
    23941 ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg aaggttacct
    24001 gatcatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg ctgaatcagc
    24061 tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg tctttaagaa
    24121 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    24181 gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg tttcaggtta
    24241 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    24301 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    24361 tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    24421 tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt cctgcagact
    24481 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    24541 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    24601 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    24661 aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    24721 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    24781 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    24841 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    24901 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ctgggactta
    24961 acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    25021 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    25081 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    25141 atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca agctgggatg
    25201 gaatttgaaa cagctgccag cgtagccttg accttctttg acgatgcctt ggtggcagca
    25261 gacgaggaag tcttggaccg tttgggtaaa ttgccacatt taacagctgc cattcgtcag
    25321 gctaaaatca aaaaagccca ctacttaggg gcagatgtgg agaaggcctt gacaaatctc
    25381 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    25441 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    25501 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    25561 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    25621 aaactcttgg ctgatatgaa gggatatgac tctgtctttg actatcttct agctgaacaa
    25681 gaagtggacc gtgtcatgtt tgatcgccag attgacctca tcatgaagga ctttgcacca
    25741 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    25801 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    25861 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    25921 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    25981 tatgcagcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    26041 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    26101 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    26161 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    26221 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    26281 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    26341 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    26401 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    26461 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    26521 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    26581 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    26641 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    26701 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    26761 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    26821 gaacgtggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    26881 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    26941 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    27001 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    27061 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    27121 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    27181 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    27241 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    27301 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    27361 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    27421 atgatgaaaa tatctggttt cataaaaatt ttctccaaat ttcatatatc gatgattttc
    27481 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    27541 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    27601 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    27661 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    27721 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    27781 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    27841 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    27901 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    27961 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    28021 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    28081 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    28141 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    28201 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    28261 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    28321 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    28381 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    28441 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    28501 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    28561 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    28621 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    28681 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    28741 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    28801 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    28861 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    28921 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    28981 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    29041 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    29101 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    29161 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    29221 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    29281 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    29341 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    29401 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    29461 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    29521 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    29581 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    29641 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    29701 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgatcttgtt
    29761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc
    29821 attgctgagg tggtcttagc tgatggaggg ttagataaag agattgataa ggtaggcttg
    29881 tcaacacttg aacgttcttt tagggcactt gtttatgcaa atctcttgtc tgtagatgct
    29941 aaccagcaat cggtttttta tcagggatta caatcagaaa ttcgtaatgt ccttttaaat
    30001 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    30061 tgggttcacg cttttgcaca tggagccgat ttactgaaag aggtggtttg tcatccagac
    30121 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaagaatg
    30181 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    30241 ttacaaggga agttagcgca agaacaagta gcttcttgga taaaaactgt tgattttccg
    30301 atagaagaaa gggaggattt ttacaaattt tccaacttca gaacctgtct gttggaagtc
    30361 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    30421 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    30481 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    30541 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc gtcgggacag
    30601 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    30661 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    30721 atccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    30781 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    30841 tgggtaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    30901 ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgtc ttagttatca
    30961 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    31021 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    31081 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    31141 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    31201 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    31261 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc ctaggtatgg
    31321 ttactgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    31381 gttctatctg ccacctcaaa cactgctttg agtaacctgc ggctaacttc ctagtttgct
    31441 ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat aaaggtcgtg
    31501 ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac cgtagttata
    31561 gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt ctaaatagcg
    31621 agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt cgtggaaatc
    31681 tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga cacagagctt
    31741 gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga tttgtcccag
    31801 cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt ctctagtaat
    31861 ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga ctgtttcata
    31921 gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa agacgaccaa
    31981 ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag cacgcaaaaa
    32041 gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg catatcccaa
    32101 acatcgtaat attctactt
//
LOCUS       DAVBOH010000024        31439 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOH010000024 DAVBOH010000000
VERSION     DAVBOH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.024"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..108
                     /locus_tag="VQ873_001188"
     CDS             <1..108
                     /locus_tag="VQ873_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3107451.1"
                     /translation="TNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            108..869
                     /locus_tag="VQ873_001189"
     CDS             108..869
                     /locus_tag="VQ873_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3107452.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            897..2054
                     /locus_tag="VQ873_001190"
     CDS             897..2054
                     /locus_tag="VQ873_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107453.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            2873..3232
                     /locus_tag="VQ873_001191"
     CDS             2873..3232
                     /locus_tag="VQ873_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107454.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            3308..3606
                     /locus_tag="VQ873_001192"
                     /pseudo
     CDS             3308..3606
                     /locus_tag="VQ873_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            3593..5457
                     /locus_tag="VQ873_001193"
                     /pseudo
     CDS             3593..5457
                     /locus_tag="VQ873_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5502..6354)
                     /locus_tag="VQ873_001194"
                     /pseudo
     CDS             complement(5502..6354)
                     /locus_tag="VQ873_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            6436..6507
                     /locus_tag="VQ873_001195"
     CDS             6436..6507
                     /locus_tag="VQ873_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3107455.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            6611..7480
                     /locus_tag="VQ873_001196"
     CDS             6611..7480
                     /locus_tag="VQ873_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3107456.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            7467..8189
                     /locus_tag="VQ873_001197"
     CDS             7467..8189
                     /locus_tag="VQ873_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3107457.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            8186..8716
                     /locus_tag="VQ873_001198"
     CDS             8186..8716
                     /locus_tag="VQ873_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107458.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            8720..9814
                     /locus_tag="VQ873_001199"
     CDS             8720..9814
                     /locus_tag="VQ873_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107459.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            9817..10488
                     /locus_tag="VQ873_001200"
     CDS             9817..10488
                     /locus_tag="VQ873_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107460.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            10490..11518
                     /gene="galE"
                     /locus_tag="VQ873_001201"
     CDS             10490..11518
                     /gene="galE"
                     /locus_tag="VQ873_001201"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3107461.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            11542..12786
                     /locus_tag="VQ873_001202"
     CDS             11542..12786
                     /locus_tag="VQ873_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3107462.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            12836..13195
                     /locus_tag="VQ873_001203"
     CDS             12836..13195
                     /locus_tag="VQ873_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3107463.1"
                     /translation="MISRIGDIMFDFANNTFLAGLNPTSLSVVAIYQSLESMIGVLFN
                     LFGGVIADSFKRKKIIITTNILCGIACITLSFISQEKWLVYAIVITNVILAFMSAFSG
                     PSYKAFTKEIVKKDSIS"
     gene            13247..13999
                     /locus_tag="VQ873_001204"
     CDS             13247..13999
                     /locus_tag="VQ873_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3107464.1"
                     /translation="MIAIFLYKLLGIHGVLLLDGLSFLIAASLIFFITPVNEEVDTKE
                     NMTIRGIFDDLKIGFTYVYSHKQILTIIALSALVNFFLAAYNLLLPYSNQMFGSISSG
                     LYGTFLTAEAIGGFIGAILSGFINKSLSSKRLMLFLAYSGLMLMLTAPIYYMFRNVII
                     LAFTPALFSLFLSIFNIQFFSIVQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVL
                     NPNNTFNFFIIGVSITILSLIFSTLLKRYDRS"
     gene            14679..14900
                     /locus_tag="VQ873_001205"
     CDS             14679..14900
                     /locus_tag="VQ873_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107465.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15348..15650
                     /locus_tag="VQ873_001206"
                     /pseudo
     CDS             15348..15650
                     /locus_tag="VQ873_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15806..17035
                     /locus_tag="VQ873_001207"
     CDS             15806..17035
                     /locus_tag="VQ873_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3107466.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            17055..19751
                     /gene="ppc"
                     /locus_tag="VQ873_001208"
     CDS             17055..19751
                     /gene="ppc"
                     /locus_tag="VQ873_001208"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3107467.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    19834..20051
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20164..21168
                     /locus_tag="VQ873_001209"
     CDS             20164..21168
                     /locus_tag="VQ873_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3107468.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            21237..22103
                     /locus_tag="VQ873_001210"
     CDS             21237..22103
                     /locus_tag="VQ873_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107469.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            22100..22858
                     /locus_tag="VQ873_001211"
     CDS             22100..22858
                     /locus_tag="VQ873_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107470.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ873_001212"
     CDS             22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ873_001212"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3107471.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ873_001213"
     CDS             24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ873_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3107472.1"
                     /translation="MATKQKKVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            25834..26163
                     /locus_tag="VQ873_001214"
     CDS             25834..26163
                     /locus_tag="VQ873_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3107473.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ873_001215"
     CDS             26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ873_001215"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3107474.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            27337..28662
                     /locus_tag="VQ873_001216"
     CDS             27337..28662
                     /locus_tag="VQ873_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3107475.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            28693..28869
                     /locus_tag="VQ873_001217"
     CDS             28693..28869
                     /locus_tag="VQ873_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3107476.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            28928..29062
                     /locus_tag="VQ873_001218"
     CDS             28928..29062
                     /locus_tag="VQ873_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3107477.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            29126..30436
                     /gene="obgE"
                     /locus_tag="VQ873_001219"
     CDS             29126..30436
                     /gene="obgE"
                     /locus_tag="VQ873_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3107478.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            30446..30604
                     /locus_tag="VQ873_001220"
     CDS             30446..30604
                     /locus_tag="VQ873_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107479.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT        10503 a         4775 c         6355 g         9806 t
ORIGIN      
        1 acaaatatct atttagtaga aaattttgat gaaatagaga gatatagcgg ctatttggat
       61 ggaattgaac gtatgttaga gatatctgaa aaacggatgg tagcctagtg gaaatccaag
      121 attatactga cagtgaattc aaacatgctc tagcacggaa tcttcgttca ctgacaagag
      181 gaaaaaagtc cagtaagcaa cctatagcga ttttgctcgg agggcaaagt ggtgccggta
      241 agactacaat tcatcgtatt aaacagaaag aatttcaagg aaatattgtt atcatagatg
      301 gagatagttt tcgttctcag catccacact atttagaact gcagcaagaa tatggcaaag
      361 atagtgtaga atacaccaaa gattttgcag gtaaaatggt agagtcttta gtaacagaat
      421 tgagtcattt gggatacaat cttttgatag agggaacttt acgaacagtt gatgttccaa
      481 agaaaacagc acaactcttg aaaaataagg gatatgaagt acaattagcc ttgattgcga
      541 caaagcctaa gctgtcctat ctgagcactc ttattcgata cgaagaactg tacgctatca
      601 atccaaatca agcacgcgca acaccaaaag aacatcatga tttcattgta aatcatctag
      661 ttgataatac acgacaattg gaagaactag ctatttttga aagaattcaa atttaccaac
      721 gagatagaag ttgtgtatat gattcaaaag aaaatacaac ttcagcagca gatgttcttc
      781 atgagttatt gtttggagag tggagtcagg tagaaaagga gatgttgagg gtaggggaaa
      841 agagacttaa tgaattactt gaaaaataaa caattgatat ttttaggaga gtagaaatga
      901 gagggtttaa taacaagata aagtctgttt atcaagaact aacaaattcc aaagagaaat
      961 tcggtagctt tcacaagact ttaattcatt tgcatacacc tgtttcttat gattacaagc
     1021 tattttctaa ttggactgca acgaaatata gaaaaattac tgaagatgaa ctatatgata
     1081 tattttttga aaataagaaa ataaaagttg ataagacaat tttttttagt aattttgata
     1141 aggttgtttt ttctagttca aaagaatata ttagttttct tatgttagca gaggcaatca
     1201 taaaaaatgg aatagaaata gttgtagtaa ctgatcataa tactaccaaa ggtattaaaa
     1261 agttacaaat ggcagtctca atcataatga aaaattatcc gatttatgat atacatcctc
     1321 atattttaca tggagtagaa attagtgcag cagataaatt gcatattgta tgtatatatg
     1381 attatgaaca agaatcatgg gttaatcaat ggttaagtga aaatattata agtaagaaag
     1441 atggaagtta tcaacattca ctgactataa tgaaggattt caataatcaa aaaatagtta
     1501 actatattgc tcatttcaat agttatgaca ttttgaaaaa aggttctcac ttatcaggtg
     1561 catataaacg aaaaattttt tctaaagaaa atacacgatt tttggagttt aatattaact
     1621 cgaaagaatc ttcgcaacaa cttgatattc tctataaaga agttggtgta ttaagtttgg
     1681 gacaaaaagt tgtagccatg cttgattttt tattagcata tagtgactat tctaaagact
     1741 tcagaccatt gattattgat cagcctgaag acaatctaga caatcgttat atttacaggc
     1801 atttagttca gcagtttaga gatgtgaaag ctcaacgtca aattatttta gcaacacata
     1861 atgctacaat tgtaacaaat tctatgacag atcaagttgt tattatggag tcagatggag
     1921 ttaacggatg gattgaatca cagggatatg ttagtgaaaa atatataaaa aatcatatca
     1981 tcaatcaatt agagggagga aaagattcct tcaagcataa aatgtctata tatgagacgg
     2041 ctttatcaga gtagagtcag aaaaagtagg ttagaaattt agcctacttt tttctttgtt
     2101 cgacaggcat agtgtacatc tgaggtccaa gtcctctgtg gatatttgct gcagatgaaa
     2161 ccaatagcga ctcctaagcc tgaatatcgt gatgtagggg ggataggaag gaattagcga
     2221 aatcaaggtt ctacaaacag aatcgtgact tgaagccata tatagcggat gaggaactct
     2281 aaaatccaaa taggtgtcgt aacctatata cgtaaattac gagagtaaac taggaaagat
     2341 gtacggctta ttccgtgagc gtttaggacg tagtacaacg aatcatggga gtcagctgaa
     2401 cacatagtat tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa caattaaatg
     2461 aatacctctc taattaaatt tgtcaattct aattcctggt atgaaaagac agtgacctaa
     2521 aaatgtaaac gatgggagct gatcataaat ataggacggt acatgcagtg gtgttagaga
     2581 ttagtcccta cttgatttgt gataacttcc ccaactttct tctgctatac ttttctcaac
     2641 ttttaaaaat ccaactaaga attttacctg ggagtttggg ggcgtagcca ccaagttatc
     2701 ttatggttag ctgtcaaaac tggaaggttt tggttagctg gcgatatgat tttttgggta
     2761 ttgtgaccac aatgcctgag ctcgcaaaga ccgaacaagg actttaagaa atttcccgta
     2821 tgacacacgg ggtcggggtt tacccgagaa aggatgaaag tgaggaaaag agatgtctga
     2881 acagtaccgt gacattcgaa aagaggtaaa tctaaccgca gatgagctaa aacagattga
     2941 aaaaatgatg gaggttgata attatcgtca cttttcacca ttcgtcaggg ataaaatttt
     3001 gatgactgat gacaaacagt tagctgccaa agaatggttt tccctttggc agtctcaaaa
     3061 gtttgaacag atcagtcgag atgtgcattt ggttttgatt atcgcaagag agaatcatca
     3121 agtgactcaa gagcacgtct caatcttatt gacttgtgtt caagaattaa ttgtagaagt
     3181 caatcaagct cagccactca gtcgtgaatt ctgtgaaaaa tatatgggat aggagactgc
     3241 tatggtttat cgttatcgta ctaatctaaa aaaatatttc taactgattc agaattgaat
     3301 taattaaatg atcgtattac taagagtcac tgtcaaaatt tctcagtcta cgccagaaaa
     3361 gttttgctta atcccaatat gtcatttgtc acgattaaca ctgatactta tgaacagtta
     3421 gtgtttgaat tgaggaggat tggaaataac atcaatcaaa ttgcgcgtgc gattaatcaa
     3481 agccatctga tttctcagga ccaattacaa gaattgagta aaggagtcgg agagttaatt
     3541 aaggaagtgg acaaagaatt tcaagtggag gtgaaaagac tgaaggagtt tcatggtagt
     3601 tactaaatac tttgcgacgc acggaaaaaa atatcgtagg cgtttgatta aatatatcct
     3661 caatccagat aaaacagata atctaaaatt agtatctgat tttggcatga gtaattactt
     3721 agattttcct agccatgcag aaatggtaga aatgtacaat gttaacttta ctaataacga
     3781 caagttgtac gagtccagaa atgaccgaca agaaaaacac caacaaacta ttcatgccca
     3841 tcatctcatc caatcatttt ctcctgaaga taatctgaca cctgaagaaa ttaaccgcat
     3901 tggttatgag accatgatgg aattgacagg aggtcgtttt aagtttatcg tagcaactca
     3961 cacagacaaa gatcatgttc ataatcacat cctaattaac gctattgacc gcaattcaga
     4021 taaaaagttg atatggaact atgccttgga acgaaacctc cgtatgattt cagaccgtat
     4081 ttctaaaatg gctggtgcaa aaattattga gaaacgttat tcctatcgag attataaaaa
     4141 atataaggaa tctagtcata aatttgaatt gaaacaacgt ctttattttt tgcttcagca
     4201 atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc agattgattt
     4261 tagtcaaaag catagccgtt ttttgatgac agatagaacg atgataaaac caattcgagg
     4321 tcgccaactt agtaaacgag atttatatga tgaagacttt tttaaaacat attttgccaa
     4381 acaagagatt gaaagtcatt tagaattttt gttgaaccgt gtcaattctt tagaagagtt
     4441 aataacaaaa gcaaaagaat tgaatctaac cattgactta aaacaaaaaa atgtaacttt
     4501 tatcctggaa gaagataatc aaaagataag tttgggtcat aaaaaataag tgataagaaa
     4561 ttatatgatg tcaaattttt tcaagattat tttaaaaata aggaagtcgt tgcttcagaa
     4621 ggattagaga atttatagga acagtaccat gctttccaag aagaacgaga taaggataaa
     4681 gtatccactg aagagattga ggaagccttt gagatattta aggaaaagag agatgctgtt
     4741 cgtgaatttg aagtggaact tgcagagaac caaatagaga agctagttga tgagggaatt
     4801 tatatcaaag tgtcttttgg tattaagcag agtggtctta ttttcattcc caattatcaa
     4861 ttggatacta tggaagaaga caatcagaaa aaatataaag tctacattcg agaaacgtct
     4921 tcttactttg tctataataa agaaaacatg gataataatt gtttcatcaa gggtaggacc
     4981 ttaatcagac aattgagcaa cgatagccaa aaactcccct atagacgacc aactttaaaa
     5041 agtcttcaag agaagatttc taaaattaat cttatgattg aactatctaa cacgaacaaa
     5101 caataccaag aaatcaaaga tgagcttgta ttagaaattg cagagattga tatgcagcta
     5161 gaagaaaccc aagaaaaaat cgccacctta aacaagatgg cggaagtcct tatcaatttg
     5221 aagagtgaag atcatgagac tagaaaatta gctaagtatg attttgacca aatgaacatg
     5281 acggaatcaa taatgttaga tcgactcaat acggatattt taaaattaca acaggaactt
     5341 ggtaatgaaa ttaataaata tgaggagata gctagaagat tggatttgtt tgtgaaaatt
     5401 attaatacca ataaatttac agttctaaaa tttcacgaga atgccttact agaataatat
     5461 tatttacgac taattagtta aaagatagag aataatttca tttatttttt atttactagt
     5521 ttattaaaat ggtcagtata gtgtaatttt aacttgtatt ctcctaaaat atcgagaact
     5581 tgtatagctt gtttcattgt ttcaatacca ctacttaatt gacgtttaaa ttcatagtaa
     5641 ccggttgcat agagaaaaac tgtctgttca taaaagttta attcattctc taacaatccc
     5701 tttatctcat taattaaata agagcaatta gaaaattctt ctttatctat gctgagaatg
     5761 aaacaattta tagctagctg agtgacaatc cgcttatttg ttttatttag agatgagtaa
     5821 atataattat ttaacatttc tttagttaag taagaagtag gagttgtagt taattgttcg
     5881 tacacagtta cctaataaaa taatctcata ataaccccat ttttcaactt taaagagata
     5941 atctgctagt tgaagtaatt catcatctga tggaatgatt cttgaatcca ttgtgtgtaa
     6001 aatggatttt accattgttt tttcaaaaga atctaaagtg taatttgagg aatccgaaag
     6061 tagagattgt atattattga tgttttgtaa tgaatattgt ttacggatat actgtattaa
     6121 gttggcaaat gactcagttt ttgtatagtc ttcatcgtgt aaaataagaa actcatccaa
     6181 agtaatgtgt aatttgtcta aaatattgat cagtcggata catgatatct ctgactctcc
     6241 acgttcaaat cgggatattt gcgattttga aagatgctca tcagcaacag agcatagact
     6301 gatttgtttg cctttacgaa cttttctaag tgtgatgcca agttttgatt tcatagtttt
     6361 tcccattttc ccaacaaaaa gttaacttag ttttatttat tgtacaataa ataaaaattg
     6421 aaaggaagtc taaatatgaa gaaaatttca aaatttttcc caattttgat gctagtgatg
     6481 gacattatca ttattgttgg tggttaaatc acttaggtgt acacctaagt ctttagagta
     6541 tctaaagact atacttacta gctaaaacat atttaagtta aatcgtaaaa ttttagagag
     6601 tggtgagact ttgaaacata aaaaagtatt aattataggg tatggtataa tgactcgggg
     6661 tatattaaaa atcctgaaac agtcgaaaaa atataatata tacctatata gtaggcatct
     6721 aaattcaaca ataaatggaa taatatttat tagagaagat gaattacctg atgctataaa
     6781 tcaggttgat tttataatca cttgttttag taatcatatt gaaacggata atttcattaa
     6841 tgagttttta ttaaatatac aatcacttcg taaaaccata gtaattgatt ttacaacctc
     6901 caggattgat tgcgttgaaa aatttaaaaa aactgttgaa attaaagggg gatactatat
     6961 agaggctcct ttcacaggag gtaagttagg aagtaatagt ggtcaactat caattttttt
     7021 acatattgat gaaggtgtaa actataataa aaaggagtta atggaattat taaaattaat
     7081 ttcaaaaaaa atatactttt ttgaaaagag tacggaacca acaaaattca agttaattta
     7141 taactcgtgg ggagcgtatt tgctttactc tattaagcta ttcaaccctt tacagtatga
     7201 tttttcacca aagtctctag aggtagcgaa tacaatcgta tgtaatgatg gttggatgag
     7261 tttagtatgc aactccaaat tagaacagat caatgatcaa gattttgatg acatacactt
     7321 tagagtagaa tatatggtaa aagatttaga atatgctaat ttttcagtct ttcatgatga
     7381 agtgaaagaa ataaattatt tattacagca atatagggat tgcttagtaa ctgatagtgg
     7441 aaaagattat acggtaatag gaaagtatga taacttatag gaatgacttg ctgtctaaag
     7501 aattagatat actaatttca ttttttaaaa aatgcgaggt aggaaaaatt tcactcgtta
     7561 ttactggttc cttggcaaga ggtaatccaa gaatcaagga tgggaaatta gaatcggata
     7621 ttgatattct agttatagta gacagtattc agcaattaat tagtataaaa aagactttag
     7681 agggaaggtt tcactttgta cataaaattt ctttgatttt ttgtttgaag gaaagaataa
     7741 atcgaagtcg ttatcgtgga attattaata gtattagaag tgtagataat cttttagtag
     7801 ataatctgca tataaaaaat caaataatag aagctttaga ctcacctacc aatattgtgg
     7861 agcagactcg ctctatgatt caggaatttt gttattattc atcaaaatat ttaatttcaa
     7921 agaataatta tttggaatta aaactagaaa agtattggaa ggagattgca acattaaatc
     7981 atatcgataa aaagataaaa cacctagatt ttgaaagaat atttgctgtt ttaaaagaac
     8041 acaaaataca aattttggat tcaagtgaat attttttcca aaatgtaaaa acttctgaga
     8101 atatttattt agagatgagg gatttagtat ctttggaaaa tcaaggatta gactttgaac
     8161 attgtatttt gagcttgggg gaaagatgat aataaataca ttaggaccaa ctgcaacaga
     8221 ttgtttttat gcaataaatc gtataaaatt aaaagtagat gtgattgtac tgtatgatag
     8281 ttttgatagt atagttaatt gctttgataa attaaaaggg caatatatat tattacctgt
     8341 agctttcgag agtagtatta aaaattatag ttggaaagat ttcaactttg aatatcataa
     8401 gcggattgaa attgtggatt cttttcactc ttttactaag ggaatggttc taatcgagaa
     8461 ttgtaattat aaaattaata gggcgattat ccaacctgca actgagattt tgatgttaaa
     8521 ctatttaaag aaaaaaagta tggatctgag gatagatttt acccatagta aagttatggc
     8581 aaataaaaaa tttctggaag aaggttatcg tttttcaata gtaagccaag aaacgataat
     8641 taataatgat gatattatta tttgtgaaac tttctctcca gaaatgattt ggtgcttata
     8701 tagagtgaaa ggatagaaaa tgttttctga aattattaag aaatatgata ttgttacact
     8761 gaaagatagt ggttttttga gaggtgattg gttcataggt tcagcgttaa tggctcatga
     8821 ctatgaaagc cttaaggaag ggatatattt ctatccccag gaaacaattt ggacaagaat
     8881 cttggattta gaatatataa atccgtattg ggaaatatat aatcaaactt ataatttctt
     8941 attagttaat aaacaagatt cattagcaat gaatttttta actagtcttc taagagaaat
     9001 agaagttatt tcgtctaaaa cattagattt tgttgttatt acttcaaacg aacacctaat
     9061 taggaattta attgatagag actattatat tattacaaaa gagattccat tttttattga
     9121 aaactcaaaa gttggaaatt attttaaaat ttttgtgaaa aatggaggac agtttattcc
     9181 tataattgac tgtacggaat ttaagattca gtctaagaaa tattttgaga taaatattaa
     9241 taaattctac ctgaaacttt tggattactt tcttcatgga gagattccag aaaaatttaa
     9301 attttttgga aatacctcta atttcaatat agaaagcttg tttctagaat ttattgatag
     9361 ccaagaaaat attcgagtag tttccttgtt ggattgtctt attcaattat cctctaaaaa
     9421 tattgaaatt tcaggaaatt ataaagggca cacagtgaaa aaaatactaa aaaaattcgc
     9481 tttatactca gtaattacca aacttgatat aacgaaagta aatcatttat tgagaaatga
     9541 ttatatctac tttttaatga aggaaattga caatattact aaaaaatatc caaagttaat
     9601 tcaaaagtac cctagagata tcttgagtga taggtatgga ataacaaatg aagtatatag
     9661 atacttaatc ggagagaatt tacatataaa aattaatcat aaattagatg aggttagata
     9721 ttttacagat attccattta ttgatacttc actttctatt gaagagtttg acaaaatagt
     9781 ttctaaaata ttaaaaatta aagtgggagg gtaactatga taagattacc aaataaattt
     9841 aaaggtaata atataactct agaagttaaa ctaaataaag cagttgatgc tagtgtatta
     9901 tacccagatg ttaagtctct agatcaagaa ttgtatcgac aactacaatc agtagaatca
     9961 ttctatctta ccttttctga tatgtattca gaaattaatg aaaataatga aatcttatat
    10021 acagaaataa tctttaagat acctctttgt attggagaag attattttaa ttttccggtt
    10081 gtatcatatg tttcaaatcc ctattcgtta ataagaggat tttatctagg ttttcataag
    10141 gaattggact gtaactatgt atttgatgat gtagagcttc atttttttag ggaagggatt
    10201 tgtgaattta acttcgaatt taaaaatcaa aattcaatca ttacagcaga attaccaagg
    10261 gagtataact atcccttgat cttgtttaat aattccaatc tggttaatca atatggaaaa
    10321 tatactttgt tagacataga caaatataaa ttagagtcta gaaagatttt tgaatttcca
    10381 gaaatttcta tcggtaactt tcttggaagt gaagcaaaat caaatagggt aatttttagc
    10441 caagataaat ttcaaattaa tggcataaag aatatggagg taaattagca tgaaatcatt
    10501 attaataaca ggtggagcag gatacatagg atcacatacg gttttggact tgttagataa
    10561 taattatgaa gtaacaatca ttgatgattt gagtaactct aagaaaaaag ttattgagtc
    10621 tattaagcag atatccaaga agagtagaaa tcttcatttt tataaaattg atttaaaaaa
    10681 tgaagaaaaa ttggaaaatg tttttaagag acataatttt gatggagtaa ttcattttgc
    10741 agggtataaa gctgttggag aatccgtggt tgaaccattg aagtattatg aaaataattt
    10801 attatcaact ataaatattt taaaactaat gaaaaaatat aaggtattta attttgtgtt
    10861 tagttcatca gctactgtat acgaaagtac tcctatcatg ccattctatg agactaatcc
    10921 attaaaagct tcaaacccgt atgggagaac aaaacagtat atagaagtac ttttaaatga
    10981 tttgtttatt tcgaattcaa attggaaaat tgtttgtctg aggtatttta atccattggg
    11041 tgcacatgaa agtggtgatt taggagagga tccaaatgga attccgaata atcttgttcc
    11101 ttacattaca caagttgcaa ttggaaaatt accatattta aatatattcg gagttgatta
    11161 cagtactcct gatgggactt gtataaggga ctatgttcac gttaacgatt tagcagacgg
    11221 acacagaaaa gcattagagt atatttttaa tacagatgaa ggtttatatg aagtaatcaa
    11281 tttaggaagt ggtgttggtt ttagtgtatt tgaaatccta cacagcttag agagtgtcat
    11341 aggctcgtat attccatata agataacttc aaggagagca ggagatatgg acgtttcaat
    11401 tgcagatatt tcaaaagcag aagagctact gggatggaag ccaaggtatg atattatgaa
    11461 aatgtgccaa gatacgtgga aatggcaaca gaaacatcca aatggatatg atgactaata
    11521 attgaaagga ttgggattaa catgcatata gtattattta gatattctgc acgggttgtt
    11581 aaactaaaat atctgtataa cagaaatgta gtaattattg cacctgaggt tcaaagaaaa
    11641 aaatatgaag attatctagc tgaaggaaat aatctaccta aggtcatttt tttagaagat
    11701 tttattctac caaatatcat cttagaaatt agaaggataa gtcaaaatac agaagttgag
    11761 agtattacaa ccttgagtga ggaagacatg gatatagtag gttttttgaa tgatcatttt
    11821 gtagaaaaaa atactcactc tgtgtctaat ttattattta aagacaaata cttcatgcgt
    11881 tcatttttag ttggagtagt aaatcaaccg tattttaggc ttttagaatc agaaaatgat
    11941 ttacgtgttt tttggaataa ttgtaaatct tctgctgcaa ttttaaaacc tagaaatgaa
    12001 gcaggaagta atggaataaa aaaagtttac cctaacgaga aaattgattc agtgtatttt
    12061 gaaaaaaact atattataga ggaatacatt gatatcgata acatgataac atgtgatggt
    12121 tattcaattg gaagtgagat taagcgattt tatgttcacg aatatgagga actattgttc
    12181 aataccttaa gttctagtgg atattatctt gtaaggacta gttcgttata taatgatagt
    12241 gaaaaaattg aatacataga aaaagcattg gaagaatgtc gcaaagtttt gaatgttttt
    12301 tctatcaatt ctgaaataac cccttttcat tttgaatggt tccttgaatt atcaactggt
    12361 aaaatagtct tttgtgaagt tggaaaaaga tttggagggg gagatattcc ccagttaatt
    12421 gaggatagtc atggagttga tgtaattaaa gaatattggg atattttgac taattcacaa
    12481 gtattgaaaa aaataaattt ttctaaagtg atttctagac ctgctaatat ctcagcaacg
    12541 tttgctttat atagaaagca aggtaaggtt atcgaggtac ctgatgaaaa agaattggct
    12601 tgggcaaaaa aagtgtacat atttattaaa ccaaatactt actataaagt atctgaaaat
    12661 gtagtcgaaa attcaatgtt tgtccaattt aattgcaaaa atagttgtga atttgagaaa
    12721 aggttagatg aacttaagca catatcacaa aagtttaaat atgtgattac tgattcggga
    12781 gaataaaatg attagagaag aacatcacaa tattctatcc attgtagcta gtaggatgat
    12841 atctcgaatc ggagatatca tgtttgattt cgccaataat acctttcttg ctggtcttaa
    12901 tccaacatct ctatcagtgg ttgcaattta tcaatcatta gaaagtatga taggtgttct
    12961 atttaattta tttggtggag ttattgcaga tagtttcaag cggaaaaaaa ttattattac
    13021 tacaaatatc ttatgtggta ttgcttgcat aactctttca tttatatccc aagaaaaatg
    13081 gttggtttat gcgatagtca taacaaatgt cattttggct tttatgagtg ctttttcagg
    13141 gccatcatac aaagctttta cgaaagaaat tgtaaaaaag gacagtatat cataacttaa
    13201 ttcattgcta gaaacaacaa gtactgtgat taaagtaaca attcctatga ttgcaatttt
    13261 cttatataag ttacttggaa tacatggtgt gttattacta gatggattat cgtttttaat
    13321 tgctgcctca ctaattttct tcattactcc tgtaaatgag gaggtggata caaaagagaa
    13381 tatgacgata agaggaatct ttgatgattt aaaaatagga tttacgtatg tatatagtca
    13441 taaacaaatt ctcactataa ttgccctttc agcacttgtt aactttttcc tagcagccta
    13501 taatttgttg ctgccataca gtaatcaaat gtttggaagt atttcaagtg ggctatatgg
    13561 aaccttttta acagccgaag cgattggtgg ctttattggt gcgatattaa gtggatttat
    13621 caataaatcc ttgtcaagca aacgtttaat gctcttttta gcatattcag gtttgatgtt
    13681 aatgctaaca gcgccgatct attatatgtt ccgcaacgtc attattttag cctttactcc
    13741 agcattattt agtctatttc tttccatttt taatatccaa tttttctcta ttgttcaaag
    13801 agacgtagat aatgagtttc ttggcagagt atttggaatc atctttacgg tagctattct
    13861 ttttatgcca ctaggtactg tttttttctc agtagtttta aatcctaaca atacttttaa
    13921 tttttttatt attggtgtat ctattacgat attatcgcta atatttagca cgctattgaa
    13981 gaggtatgat agaagttgat agatgataaa aaatagctga tatagagaat ttagagcgcc
    14041 tttggaatat atttttggaa tttaatcaat cacagttgaa tgtgaagggc aatccttttt
    14101 agaagaatac aatcaagata ccattatgct atttctttag ttcagttaaa atattgagaa
    14161 gtattacttt tattgaaaaa gcatcacaaa ggactccaat taatttttaa tgatttttct
    14221 aatctaattt tgtggttatt gacaaataaa gtctagttaa ttgctttgaa atccatggag
    14281 tggtctatat acatctgtta atgcaacgga aaattttatt gataagtagg gggtggctat
    14341 tattcagctt ttaggttctg aaagtaagag attcacatta gaaatatcat gttgaccatt
    14401 tttcaatttg ctggttagta gtaatctgga catcattaat cccttcctta acaaaattat
    14461 gtgacttttg ttaccggatt actgctgatt ttttaatagc ttataacatc tttagacggt
    14521 taatagattt tgaccgtctt tcttaatatt gtcttaccta taatagatat gcttatgaga
    14581 tatgtttaat aaattaattt tagttcaaaa tgtccagttt ggacactttg aatgatttct
    14641 tagttttata tattatactt ttctcaggag aaagctagat gtacagacgt ttgagagatt
    14701 tgagggaaga tcacgatttg acccaaaaac aaatagctaa aatactttcg tttacagact
    14761 cagcttatgc taaaattgaa cggggtgagc atacgttaac agcagatata ttggtaactc
    14821 tctcaaactt ttacgatgtc agtacagact acctattggg attgacggat tttcctgata
    14881 aaattcgctt tagaaaataa tctcctcaat ttcatagagt gtgaaaatgc gaagattttt
    14941 tttatttgtt ctttgacaat tgaatagtcc aaaatggtac tttcctcatt tgtggagcag
    15001 atttgaatgg ttcgccatga taagagcgat attaaaacca tcaataaaat agagcgatac
    15061 tttatatgcc atgatacaaa tgatatacaa tgatacttct gaccgttcag gctgccaccg
    15121 taaaagagca gcaagtgaaa ttcttatgat gacttcatca gtcatgccat gttgaatgtg
    15181 tgagtttgtt agataaacgc aattaatcct caaaaggttc cccgaacctt ttgagttcta
    15241 cagacgcatc acgtggagtg tgtaagcttg ttgctaaaag cgtaaaaacc ttggaacgaa
    15301 aggaataata gacttcctgc gaaacaaaaa tataatacaa taaaactatg aatgatgaag
    15361 caagtaaaca attgagcgat agccgtttca agatccttgt aggtgttcag cgcacgactt
    15421 ttgaagagat gttagcggtg ttaaaaacag cttatcaacg taaacgcgca aaaggtggac
    15481 gaaaaagcaa attaagccta gacgatctcc ttatggtaac tattcaatac atgcgagaat
    15541 agcgcactta tgaacaaatt gcggctgatt ttggcattca cgaaagcaac ataattagtc
    15601 ggagtcaatg gattgaagca actcttattc aaaatggttt tacgatttca aattctgcct
    15661 taattctgta aaaacagtaa aattcgaagg attgtaaggt aagagttttt ttctttctga
    15721 aaaaatggta taatagcaat caaaactaga aaataaaacg gaatttggaa cagatttgtc
    15781 tgtatcctag tagagtggtg atactatgaa gattagtaag aggcacttat taaattattc
    15841 catcttgatt ccctacttgc ttttatctat tttgggcttg attgtggtct attcgaccac
    15901 cagtgctatt ttaattgaag aaggcaagag cgccttgcag ttggttcgaa accaaggaat
    15961 cttttggatt gttagtttga tactgattgc cttaatttat aaattgagac tagatttttt
    16021 gagaaatgag cgactaatca ttttagttat attaatagaa atgcttttat tgttcttggc
    16081 tcgttttatt ggtatttcag taaacggggc atacggttgg atttcggttg caggagtaac
    16141 tattcagcca gctgagtact taaaaatcat tattatttgg tatttagctc accgattctc
    16201 caaacagcaa gaagaaatag ctacttatga ttttcaagtt ttgactcaaa atcaatggct
    16261 tccccgtgct tttaatgatt ggcgattcgt tctcctagtt ctgattggaa gtttgggaat
    16321 tttccctgat ttaggaaatg cgactatttt agtcttggtt tccttgatta tgtatacagt
    16381 tagtggaatc gcttatcgct ggttttcaac cattctggcg ctcgtatctg ccacttctgt
    16441 ctttgtcttg accactatca gcctaatcgg tgttgagacc ttttcaaaaa ttccagtatt
    16501 tggctatgta gccaagcgct ttagtgcctt ttttaatcct tttgccgatc gtgctgatgc
    16561 aggtcaccag ttagctaatt cttattttgc catggtcaat ggcggttggt ttggtctagg
    16621 tcttggaaac tcgattgaaa aacgaggtta tttgccagaa gctcatacag actttgtctt
    16681 ttctatcgtg attgaagaat ttggctttgt tggtgccagt cttattttag ctctcttgtt
    16741 tttcatgatt ttgcggatta tcttggtcgg tatccgagcg gagaatcctt tcaatgccat
    16801 ggttgcactc ggtgtcggag ggatgatgtt ggttcaggta tttgtcaata tcggagggat
    16861 ttcgggcttg attccatcta caggagtgac tttccccttc ttatcccagg gtggaaatag
    16921 tcttctagtc ttatcagtgg cagtagcctt tgtcttaaat attgatgcca gtgaaaaacg
    16981 cgctaaattg taccgagaat tggaaaatca accaatgaac cttctgttga agtaggataa
    17041 agaaaggata gtttatgtct cttcaaaaat tagaaaatta tagtaataaa agtgttgtgc
    17101 aagaagaagt cttgattcta acagaattac tggaagatat tactaaaaat atgcttgccc
    17161 cagagacctt tgaaaaaata atacagttga aagaattatc aacgcaggaa gattatcaag
    17221 gtctaaaccg tctagtgact agcttatcaa atgatgaaat ggtctatatt tcacgctatt
    17281 tctctatctt gcctcttttg attaatattt cagaggatgt ggatttagct tatgaaatca
    17341 atcatcaaaa taatattgat caggactatt taggtaaatt atctacaacg attaaattgg
    17401 tagcagaaaa ggaaaatgcc gttgagatcc tagaacactt gaatgttgtc cctgttttga
    17461 cagcccatcc aacacaagtg caacgcaaaa gtatgttgga tttaacaaat catattcata
    17521 gtcttttgcg taaataccgt gatgttaagt tggggttgat caataaagat aaatggtaca
    17581 atgatttgcg tcgttacatc gaaattatca tgcagacaga catgattcgt gagaaaaaat
    17641 taaaagtgac taacgaaatc acgaatgcta tggaatatta taacagctcc tttttgaaag
    17701 ctgtacctca tttgacgacg gagtataagc gcttagcgca agcgcatggt ctgaatttaa
    17761 aacaggctaa accaatcacc atgggtatgt ggataggtgg tgaccgtgat ggaaatccat
    17821 ttgttacagc aaagaccttg aagcagtctg cactcactca gtgtgaagtc atcatgaact
    17881 actatgataa aaagatttac caactttatc gtgaattttc tctttcaact agcattgtca
    17941 acgtcagcaa gcaagtcaga gaaatggctc gtcaatccaa ggataactcg atttaccgcg
    18001 aaaaagagct ttaccgtcgt gccttgtttg atattcaatc aaaaattcag gcaactaaaa
    18061 cctatctgat tgaggatgaa gaagttggga ctcgttatga aaccgccaat gatttctaca
    18121 aggatttgat tgccattcga gattctctac tagaaaataa gggcgagtcc ttgatttcag
    18181 gtgattttgt ggaattattg caggcagtag agatatttgg tttttactta gcatcaattg
    18241 atatgcgaca agactctagc gtctatgaag cctgtgtggc agaactcttg aaatcagcag
    18301 gaattcattc tcgttatagc gagttgagcg aagaagaaaa gtgtgacctt ctcttgaaag
    18361 aattagaaga agatccccga attctttctg cgactcacgc agaaaaatca gaattattag
    18421 caaaagaatt agctattttt aagacggctc gtgttttgaa agataagttg ggagatgatg
    18481 tcatccgtca gaccatcatt tcacatgcaa ccaacctttc tgatatgcta gaattagcta
    18541 ttctgttaaa agaagtagga ctggtggata cggaaagggc gcgtgttcag attgttcccc
    18601 tttttgaaac aattgaagac ttggatcatt cagaggaaac aatgagaaaa tatctttctc
    18661 ttagccttgc caaaaaatgg attgactcac gaaataacta ccaagaaatc atgcttggct
    18721 actctgacag taataaagat ggcggttact tgtcatcatg ttggaccctc tacaaggctc
    18781 aacaacaatt gactgctatt ggagatgaat ttggcgttaa ggttaccttc ttccatggtc
    18841 gtggtggtac tgtcggtcgt ggtggtgggc caacctatga agccattaca tctcaaccgc
    18901 tcaagtctat caaggatcgt atccgtttga cggagcaggg tgaagtaatt gggaataaat
    18961 acggtaacaa agacgccgct tactataacc ttgaaatgct agtatcggca gctattaacc
    19021 gtatgattac tcagaagaag agcgatacca ataccccaaa tcgttatgaa gccattatgg
    19081 atcaagtagt ggaccgtagt tacgatatct accgtgattt ggtctttggt aatgagcatt
    19141 tctatgatta tttcttcgag tcaagtccaa tcaaggctat ttcaagtttt aatattggtt
    19201 ctcgtccagc cgctcgtaag actattactg aaatcggtgg tttgcgtgcc atcccttggg
    19261 tattctcatg gtcacagagt cgtgttatgt tccctggatg gtacggggtt ggttcaagct
    19321 tcaaggaatt tatcaataaa aatccagaga atattgctat cttacgagat atgtaccaaa
    19381 attggccttt cttccaatcg cttctttcaa atgttgatat ggttttgtca aaatcaaata
    19441 tgaatattgc ttttgaatat gctaaacttt gtgaagacga gcaagttaag gccatctatg
    19501 agattatttt aaatgaatgg caagttacta agaacgttat cttggctatt gaaggacatg
    19561 acgaactctt agctgacaat ccatatctaa aagctagtct ggattaccgt atgccttact
    19621 ttaatattct caactatatt cagttagagt tgattaaacg ccaacgtcgt ggagaattgt
    19681 ccagtgatca agaacgattg attcatatca ccatcaacgg aattgcgaca ggattgcgta
    19741 attcaggttg ataattttca agagtgaatg ctaaaagtga atatcaaaaa aattctaata
    19801 gactattgac aagtagttta aaaatgatat aatttaacca ttcagaaaag taatcataca
    19861 aactttttag agagtctgtg gtagctgaaa acagataagt ggcgatgatg aaaattgggc
    19921 tgaatgctat ttagaatttg aaattataaa aattcggtaa gcacacctta cagtgcatct
    19981 cgttattgcg agactgagcg atagggaaat tccctataat tgaggtggta ccgcgcatcg
    20041 acgtcctcac acaagttttt tgtgtgagga tttttttgat ggaggttagt atggaaagaa
    20101 aacgatggcg tcgcttgttt agataagtga aatatgttaa aggaaataaa aaggagaaac
    20161 agaatgaaaa ataaacgttt aattggaatt attgctgcat tagcagtctt agtagcagga
    20221 agcttgattt attcttcaat gaataaatca gaagctcaga ataataagga tgagaagaaa
    20281 ataactaaga ttggtgtgct tcaatttgtg agccatccat cccttgattt gatttataaa
    20341 gggatccaag atggacttgc agaagaagga tataaagatg atcaagttaa aattgatttt
    20401 atgaactcag aaggtgacca aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat
    20461 gggaatgacc ttgtggttgg tatcgcaaca ccagcagccc aagggttggc tagtgcaaca
    20521 aaagacctac cggttatcat ggccgctatt acagacccaa ttggtgctaa cttggttaaa
    20581 gatttgaaaa aaccaggtgg caacattaca ggggtatctg accacaatcc agctcaacaa
    20641 caagttgaac tcatcaaggc tctgacaccg aatgtgaaaa caatcggagc tctttactca
    20701 agtagcgaag acaattcaaa aacacaggtc gaagaattta aggcttatgc tgaaaaagca
    20761 ggtctgacag tggaaacatt tgcagttcct tcaacaaatg aaattgcctc aactgtcact
    20821 gttatgacta gcaaggtaga tgctatttgg gttccaattg ataacaccat tgcatcagga
    20881 tttccaacgg ttgtctctag caatcaaagt tctaagaaac caatttatcc cagtgcgaca
    20941 gctatggtag aagtaggtgg tttggcatca gttgtaattg accaacatga ccttggtgtg
    21001 gcaacaggta aaatgattgt gcaagtcttg aaaggtgcaa aaccagccga taccccagtc
    21061 aatgtctttt caactggtaa gtcagtcatc aataaaaaaa tagcacaaga actaggtatt
    21121 actatccctg agtctgttct caaagaagca ggacaagtca tcgaataaat aaggtaggga
    21181 ggaggagact cttcccattt tttaaaaaga tgaatataga aaggattaaa taaaatatga
    21241 ttgtttccat tatttctcaa ggatttgtct gggctattct aggtctggga atctttatga
    21301 catttaggat tttaaacttt ccagatatga cgacagaagg ttccttccct cttgggggag
    21361 ctgttgctgt cactttgata accaaaggcg tgaacccatt tttagcgaca cttgttgctg
    21421 taggagcagg ttgtttggct ggaatggcag caggccttct ttatacaaaa gggaagatcc
    21481 caaccttgct ctcagggatt ttggtgatga cttcttgtca ctcaatcatg ctcttgatta
    21541 tgggacgtgc gaatttaggc ctgcttggaa ccaagcaaat tcaggatgtt ttgccttttg
    21601 attcggattt gaatcaactc ttgacaggtc tcatctttgt gagtattgtt attgctctca
    21661 tgctcttttt cttggacact aaactcggac aagcctatat tgctacaggg gataatcctg
    21721 atatggctag aagtttcggg attcatactg gacgcatgga gctcatgggc ttggtcttat
    21781 caaatggtgt gattgccctt gcaggtgccc tcattgctca gcaagaaggt tatgccgatg
    21841 tgtctcgagg gatcggggtt atcgttgtgg ggcttgcaag tttgattatt ggagaagtta
    21901 ttttcaagag tttgagcttg gcagagcgtt tggttactat cgttgtaggt tctatcgctt
    21961 atcaattttt agtgtgggca gttatcgcac ttggctttaa tacaagttac cttcgtttat
    22021 acagtgcctt gattttagca gtctgcctca tgattccaac atttaagcaa acaatcttga
    22081 aaggagccaa gttaagcaaa tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt
    22141 taaaaatggc tttgatgaag aaaagattat tttaaatgat gtttccttag aaatttttga
    22201 acgggacttt atcacgattt tgggcggaaa tggtgctgga aaatcaaccc tctttaacac
    22261 tatagcaggg accttatcac taactagtgg aactatccgt attttaggtg aagatctcac
    22321 taagttttca cccgagaagc gtgccaagta cctgtctcgt gtcttccaag atccaaagat
    22381 ggggacagct ccccgtatga cggtcgctga aaatctttta atcgccaagt ttcgtggtga
    22441 aaagcgtgga ttgttaccac gacgcttgac tagctataag gatgaatttc aggtaaccat
    22501 tgaaaaagta ggaaatggtc ttgagaaaca cttgaataca ccgattgagt tcttatcagg
    22561 tggacaaaga caggctttga gtctcttgat ggcaaccttg aagcgacctg aattactcct
    22621 gttagatgag catactgctg ccctggatcc aaagactagt gttgctttga tggaattgac
    22681 agatgaattt gttaagaaag atcagctaac agcccttatg attactcatc atatggaaga
    22741 tgctctcaaa tacggcaatc gcttgattgt catgaaagaa ggacggatta tccaagattt
    22801 aaaccaagaa gaaaaagcaa aaatgaaaat ctctgattat tatcaactct ttgaataaag
    22861 tagggaaaat gagtgaaata gtttactttt tttctgaaat aaagtatact atatatagta
    22921 tactatgata acatggaggt attgtgtatg gttgacaaac aagtcattga agaaatcaaa
    22981 aacaatgcca acattgtgga agtcatagga gatgtgattt ctttacaaaa ggcaggacgg
    23041 aactatctag ggctctgtcc ttttcatggc gaaaaaacac catctttcaa cgttgtagag
    23101 gataagcagt tttatcactg tttcggttgt ggtcgctcag gtgatgtctt taagttcatc
    23161 gaggagtacc aaggggttcc ctttatagag gcagtccaaa tcttaggtca gcgtgttgga
    23221 attgaggttg aaaaaccgct ttatagtgag cagaagtcag cctcacctca ccaagctctt
    23281 tatgatatgc acgaagatgc agccaaattt taccatgcta ttctcatgac aacgactatg
    23341 ggagaagagg ccagaaatta cctttatcag cggggtttga cagatgaagt gcttaaacat
    23401 ttttggattg gtttagcacc tccagaacga aactatctct atcaacgttt gtctgatcag
    23461 tatcgtgaag aggatttact ggattcaggc ctgttttatc tctcggatgc caatcaattt
    23521 gtagacacct ttcacaatcg cattatgttt cccctgacaa atgaccaagg aaagatcatt
    23581 gccttctcag gtcgtatctg gcaaaaaacg gattcacaaa cttctaagta taaaaacagc
    23641 cgatcgactg caatttttaa caaaagttac gaattatatc atatggatag ggcaaaaaaa
    23701 tcttctggaa aagctagtga gatttacctg atggaaggat tcatggatgt tattgcagcc
    23761 tatcgggttg gaatcgaaaa tgctgtggcg tcgatgggaa cggccttgag tcgagagcat
    23821 gttgagcatc tgaaaaggtt aaccaagaaa ttggttcttg tttacgatgg agataaggct
    23881 gggcaagccg cgatattgaa agcattggat gaaattggtg atatgcctgt gcaaatcgtc
    23941 agcatgcctg ataacttgga tcctgatgag tatctacaaa aaaatggtcc agaagacttg
    24001 gcctatctat taacgaaaac tcgtattagt ccgattgagt tctacattca tcagtacaaa
    24061 cctgaaaaca gtgaaaatct gcaggctcag attgagttta ttgaaaaaat agctcccttg
    24121 attgttaaag aaaagtccat cgctgctcaa aacagctata ttcatatttt agctgacagt
    24181 ctggcgtcct ttgattatgc ccagattgag cagattgtta atgagagtcg tcaggtgcaa
    24241 aggcagaatc gcatggaaag aatttccaga ccgacgccaa tcaccatgcc tgtcaccaag
    24301 cagttatcgg ctattatgag ggcagaagcc catctactct atcggatgat ggaatcccct
    24361 cttgttttga acgattaccg tttgcgagaa gactttgcat ttgctacacc tgaatttcag
    24421 gtcttatatg acttgcttgg ccagtatgga aatcttcctc cagaagtttt agcagagcag
    24481 acagaggaag ttgaaagagc ttggtaccaa gttttagctc aggatttgcc tgctgagata
    24541 tcgccgcagg aacttagtga agtagagatg actcgaaaca aggctctctt gaatcaggac
    24601 aatatgagaa tcaaaaagaa ggtgcaggaa gctagccatg taggagatac agatacagcc
    24661 ctagaagaat tggaacgttt aatttcccaa aagagaagaa tggagtaata atggcaacaa
    24721 aacaaaaaaa agtaacaaca tttgacgtac aggtagcaga atttatccgt aatcataagc
    24781 aaaaagggac agcaacagat gatgaaatca atgcaagttt ggttattcct tttaccttgg
    24841 acgctgatgg gattgaagat ctcttgcaac ggattcagga tgcaggaatt tctatcacag
    24901 ataacgaagg aaatccaagt gcgcgtgttc ttagcaatga agaagaacca gaactcagcg
    24961 atgaggactt gattgggtca acttctgcta aggtcaatga ccctgtccgt atgtacttga
    25021 aagaaatagg ggtcgttcct ctcttgacca atgaagagga gaaagagttg gcactggctg
    25081 ttgaagctgg tgatatcgaa gccaaacaac gtcttgcgga agccaatctt cgtttggttg
    25141 tttccattgc caaacgctat gtcggtcgtg gtatgcagtt ccttgacttg attcaagaag
    25201 gaaatatggg cttgatgaag gcggttgaca agtttgacta ttctaaaggg ttcaagtttt
    25261 caacttatgc aacttggtgg attcgtcagg ctatcactcg tgctattgcg gaccaagctc
    25321 gtaccatccg tatcccagtt cacatggttg aaactatcaa taaattggtt cgtgaacagc
    25381 ggaatctcct tcaagaattg gggcaagatc cgacaccaga acagattgct gaacgaatgg
    25441 atatgacacc tgataaggtt cgtgaaatct tgaagattgc ccaagaacca gtatctcttg
    25501 aaactcctat cggtgaagag gacgatagcc acctcggaga ctttatcgaa gatgaagtga
    25561 ttgaaaatcc agtggattat acgactcgta tcgtcttgcg tgagcaattg gatgaaatct
    25621 tagatactct tacagaccgt gaagaaaatg ttctgcgtct acgttttgga ctagatgatg
    25681 gaaaaatgcg cacacttgaa gatgtgggga aagtctttaa cgtaactcgt gagcgtatcc
    25741 gtcagattga agcaaaggct ttgagaaaac tacgccaacc aagtcgtagc aaaccgcttc
    25801 gtgattttat tgaagactaa gagtgaggaa aatatggctt atacagaaga gcaaattgaa
    25861 aacatcaaaa cacggatttt aacagccttg gaagaagtca tcgaccctga gttgggaatc
    25921 gatattgtca atcttggttt gatctatgag attcgttttg acggtgacac agggcaaaca
    25981 gagattgaca tgactttgac aactatgggt tgtcccttag cagacctttt gacagaccag
    26041 atttatgatg ctatgataga ggttccagaa gtaacggata ctgaggttaa attagtctgg
    26101 tatccagcct ggacagttga aaaaatgagt cgctatgccc gcattgccct aggcattaag
    26161 taaacatata aaagcatgtg agagactgtt ggaaaagcga ggaaatttcc cctcttttcc
    26221 tctagtctct cctttctttt gctgatttta ttcaaagaaa atgatataat agtagttatg
    26281 gagaaaaaga aattacgcat caatatgttg agttcaagtg agaaagtagc aggacaggga
    26341 gtttcaggtg cttaccgtga attagttcgt cttcttcacc gtgctgccaa ggaccaattg
    26401 attgttacag aaaatcttcc aatcgaggca gatgtgactc actttcatac gattgatttt
    26461 ccctattatt tatcaacctt ccaaaagaaa cgctcaggga gaaagattgg ctatgtgcat
    26521 ttcttgccag ctacacttga gggaagtttg aaaattccat ttttcttaaa gggaattgtg
    26581 aaacgctatg tattttcttt ttacaaccgg atggagcact tggttgtggt caatcctatg
    26641 tttattgagg atttggtagc agctggtatt ccacgtgaaa aagtgaccta tattcctaac
    26701 tttgtcaaca aggaaaaatg gcatcctcta ccacaagaag aggtagttag actgcgcaca
    26761 gatcttggtc ttagtgacaa tcagtttatc gtagtaggtg ctgggcaagt tcagaaacgt
    26821 aaagggattg atgactttat ccgtctggct gaggaattgc ctcagattac ctttatctgg
    26881 gctggtggct tctcttttgg tggtatgaca gatggttatg aacactataa gaaaattatg
    26941 gaaaatcccc ctaaaaattt gatttttcca ggcattgtat cgccagagcg gatgcgcgaa
    27001 ttgtatgctc tagcggatct tttcttgttg cctagttaca atgagctctt tcctatgact
    27061 attttagaag ctgcgagttg tgaggctcct attatgttgc gtgatttaga tctctataag
    27121 gtgattttgg agggaaatta tcgggcgaca gcgggtagag aagagatgaa agaggctatt
    27181 ttggaatatc aagcaaatcc tgctacctta aaagatctca aagaaaaggc taagaatatt
    27241 tccagagagt attctgaaga gcatctgtta caaatctggt tggactttta tgagaaacaa
    27301 gccgctttag ggagaaagta aaaagtgagg taatctatgc gaattggttt atttacagat
    27361 acctattttc ctcaggtttc tggtgttgcg accagtattc gaaccttgaa aacagaactt
    27421 gaaaagcagg gacatgctgt ttttatcttt acgacgacag ataaggatgt caatcgctac
    27481 gaagattggc aaattatccg cattccaagt gttcctttct ttgcttttaa ggatcgtcgc
    27541 tttgcctacc gaggttttag caaggcactt gaaattgcta aacagtatca gctagatatt
    27601 atccatactc agacagaatt ttctcttggc ctgttgggga tttggattgc gcgtgaattg
    27661 aaaattccag tcatccatac ctatcacacc cagtatgaag actatgtcca ttatattgct
    27721 aaggggatgt tgatccggcc gagtatggtc aagtatctgg ttagaggttt cctgcatgat
    27781 gtggatgggg ttatttgccc tagtgagatt gtccgtgact tgctatctga ttataaggtc
    27841 aaggttgaaa aacgggtcat tcctactgga attgaattag ccaagtttga gcgtccggaa
    27901 atcaagcagg aaaatttgaa agaactgcgt agtaaactag ggattcaaga tggtgaaaag
    27961 acgttgctta gtctttcgag aatctcctat gaaaaaaata ttcaagcagt tttagtagcc
    28021 tttgctgatg ttctgaaaga ggaagacaag gttaaactgg tagtagctgg ggatggccct
    28081 tatctgaatg acctcaaaga gcaagcccag aacctagaga ttcaagactc agtcatcttt
    28141 acagggatga ttgctcctag tgagacggct ctttactata aagcggcgga tttcttcatt
    28201 tcggcatcga caagcgaaac gcaaggtttg acctacttgg aaagcttagc cagtggaaca
    28261 cctgtcattg ctcacggaaa tccttatttg aacaacctca tcagtgataa aatgtttgga
    28321 accttgtact atggagaaca tgatttggct ggtgctattt cggaagccct gattgcaaca
    28381 ccagacatga atgagcatac cttatcagag aaattgtatg agatttcagc tgagaacttt
    28441 gggaaacgag tgcatgagtt ttatctggat gccattattt caaataactt ccagaaagat
    28501 ttggctaaag atgatacggt cagtcagcgt atctttaaga cagttttgta tcttccgcaa
    28561 caggtggttg ctgtacctgt aaaaggatct agacgcatgt tgaaggcttc aaaaacacag
    28621 ttgatcagta tgagagacta ttggaaagac catgaagaat agaaagagga acagctatga
    28681 aaaaaacaat taatgagaag cggtcgtgat aaaaagattg cgggtgtttg tgctggggtg
    28741 gcccattatc tggatatgga tccgactatc gttcaagtca tttggggtgt tcttacttgc
    28801 tgttacggag ctggaattgt agcttacatt attttatgga ttatcgcacc agtagcaact
    28861 gactattgaa aactagctca attcatgcta agataataga aaatagaatg taacgaagga
    28921 gagaaaaatg gcatttggag ataatggaaa tcgtaaaaaa actatgtttg agaaaataac
    28981 cttgtttatc gtgattatca tgctagtagc aagtttattg ggaatttttg caactgcaat
    29041 tggtgccctc agtaatctat aaaatagatt caagaaaatt tagtgactgg gatttcccag
    29101 ccctttttta aagtgagaag aaataatgag tatgttttta gatacagcta agattaaggt
    29161 caaggctggt aatggtggcg atggtatggt tgcctttcgt cgtgaaaaat atgtccctaa
    29221 tggaggccct tggggtggtg atggtggtcg tggaggcaat gtggtcttcg ttgtagacga
    29281 aggactacgt accttgatgg attttcgcta caatcgtcat ttcaaggctg attctggtga
    29341 aaaagggatg accaaaggga tgcatggtcg tggtgctgag gaccttagag ttcgagtacc
    29401 acaaggtacg actgttcgtg atgcggagac tggcaaggtt ttaacagatt tgattgaaca
    29461 tgggcaagaa tttatcgttg cccacggtgg tcgtggtgga cgtggaaata ttcgtttcgc
    29521 gacaccaaaa aatcctgcac cggaaatctc tgaaaatgga gaaccaggtc aggaacgtga
    29581 gttacaattg gaactaaaaa tcttggcaga tgtcggttta gtaggattcc catctgtagg
    29641 gaagtcaaca cttttaagtg ttattacctc agctaagcct aaaattggtg cctaccactt
    29701 taccactatt gtaccaaatt taggtatggt tcgcacccaa tcaggtgaat cctttgcagt
    29761 agccgacttg ccaggtttga ttgaaggggc tagtcaaggt gttggtttgg gaactcagtt
    29821 cctccgtcac atcgagcgta cacgtgttat ccttcacatc attgatatgt cagctagcga
    29881 aggccgtgat ccatatgagg attacttagc tatcaataaa gagctggagt cttacaatct
    29941 tcgcctcatg gagcgtccac agattattgt agctaataag atggacatgc ctgagagtca
    30001 ggaaaatctt gaagaattta agaaaaaatt ggctgaaaat tatgatgaat ttgaagagtt
    30061 accagctatc ttcccaattt ctggattgac caagcaaggt ctggcaacac ttttagatgc
    30121 tacagctgaa ttgttagaca agacaccaga atttttgctc tacgacgagt ccgatatgga
    30181 agaagaaact tactatggat ttgacgaaga agaaaaagcc tttgaaatta gtcgtgatga
    30241 cgatgcgaca tgggtacttt ctggtgaaaa actcatgaaa ctctttaata tgaccaactt
    30301 tgatcgtgat gaatctgtca tgaaatttgc ccgtcagctt cgtggtatgg gggttgatga
    30361 agcccttcgt gcgcgtggag ctaaagatgg ggatttggtc cgcattggta aatttgagtt
    30421 tgaatttgta gactaggaga ctggtatggg agataaaccg atatctttcc gagatgcgga
    30481 tggtaatttt gtttccgccg cagacgtttg gaatgaaaag aaattggaag aactatttaa
    30541 tcgtctcaat ccaaatcgtg ccttgagatt ggcacgaact aaaaaggaaa atccatctca
    30601 gtaaagaagc taaaaaatcc cgtgcctcat cagacacggg attttgtggt acgacaggca
    30661 tgtatagcaa actgaatctg gaatagcaca gcatatcttc taaaatattg ttataaattg
    30721 atttgaattt caaaattaaa ttgtttgatt cttatttcaa tttgttatag tatatctgat
    30781 gtcaaagttc tcggcgagtc aaatagcgat tcccaagcct gactatcgtg aggtagcgga
    30841 ttaaaatggt ctggggatag accgttttaa gtctgacgct ggaaataaga attgtcagaa
    30901 gaagggatag cgaaatcgtg gctctacgaa caggaacgtg ataataaggc gtatatagcg
    30961 gataagaggg cctcaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc
    31021 acgagagtaa ttgaattcgt actaagattt tctattttca ctgtaacctt ttaacgtcct
    31081 tatatcttgt atacacgagg aaagatgtac gacttatccc gtgaggtcta tcactataaa
    31141 gagaaaacga cagatagaag tgatcctgag tcacggttat ctttaaaata gattgtctga
    31201 taggacggta tgtataaaac gcttctgtga actgagagaa gggggagaag ttcttgctaa
    31261 aatttagttg aacagccgta ttccgatact tagataagag atctagtctt agctcctact
    31321 cggtttcagg ggataaaaaa ggggcaatag cgattcgaga aagattatac tcttcgaaaa
    31381 tctcttcaaa tcacgtcaat atcgccttgc cgtacgtgta ggatactgac tacgtcagt
//
LOCUS       DAVBOH010000025        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOH010000025 DAVBOH010000000
VERSION     DAVBOH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.025"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ873_001221"
     CDS             289..2790
                     /locus_tag="VQ873_001221"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3107480.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLLVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ873_001222"
     CDS             2984..3679
                     /locus_tag="VQ873_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107481.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMMARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ873_001223"
     CDS             3691..4107
                     /locus_tag="VQ873_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107482.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ873_001224"
     CDS             complement(4922..5014)
                     /locus_tag="VQ873_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3107483.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ873_001225"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ873_001225"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3107484.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ873_001226"
     CDS             6127..6699
                     /locus_tag="VQ873_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3107485.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ873_001227"
     CDS             6930..7688
                     /locus_tag="VQ873_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3107486.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ873_001228"
     CDS             7697..8500
                     /locus_tag="VQ873_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3107487.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ873_001229"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ873_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3107488.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ873_001230"
     CDS             9794..11647
                     /locus_tag="VQ873_001230"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3107489.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ873_001231"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ873_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3107490.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ873_001232"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ873_001232"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3107491.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ873_001233"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ873_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ873_001234"
     CDS             15398..16447
                     /locus_tag="VQ873_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3107492.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ873_001235"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ873_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3107493.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ873_001236"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ873_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3107494.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ873_001237"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ873_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3107495.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ873_001238"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ873_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3107496.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ873_001239"
     CDS             24247..28638
                     /locus_tag="VQ873_001239"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3107497.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ873_001240"
     CDS             28740..29003
                     /locus_tag="VQ873_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3107498.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ873_001241"
     CDS             28996..29274
                     /locus_tag="VQ873_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3107499.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ873_001242"
     CDS             29295..29447
                     /locus_tag="VQ873_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107500.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ873_001243"
     CDS             29469..30710
                     /locus_tag="VQ873_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3107501.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ873_001244"
     CDS             30720..30950
                     /locus_tag="VQ873_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3107502.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8794 a         5923 c         7247 g         8998 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcta
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgatgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOH010000026        26679 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOH010000026 DAVBOH010000000
VERSION     DAVBOH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.026"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..287)
                     /locus_tag="VQ873_001245"
                     /pseudo
     CDS             complement(1..287)
                     /locus_tag="VQ873_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(349..798)
                     /locus_tag="VQ873_001246"
     CDS             complement(349..798)
                     /locus_tag="VQ873_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3107503.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(800..1558)
                     /locus_tag="VQ873_001247"
     CDS             complement(800..1558)
                     /locus_tag="VQ873_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3107504.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            complement(1673..3652)
                     /gene="pknB"
                     /locus_tag="VQ873_001248"
     CDS             complement(1673..3652)
                     /gene="pknB"
                     /locus_tag="VQ873_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3107505.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3649..4389)
                     /locus_tag="VQ873_001249"
     CDS             complement(3649..4389)
                     /locus_tag="VQ873_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3107506.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4404..5717)
                     /gene="rsmB"
                     /locus_tag="VQ873_001250"
     CDS             complement(4404..5717)
                     /gene="rsmB"
                     /locus_tag="VQ873_001250"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3107507.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5710..6645)
                     /locus_tag="VQ873_001251"
     CDS             complement(5710..6645)
                     /locus_tag="VQ873_001251"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3107508.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6658..9054)
                     /locus_tag="VQ873_001252"
     CDS             complement(6658..9054)
                     /locus_tag="VQ873_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3107509.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9120..9434)
                     /locus_tag="VQ873_001253"
     CDS             complement(9120..9434)
                     /locus_tag="VQ873_001253"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3107510.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9459..10085)
                     /gene="gmk"
                     /locus_tag="VQ873_001254"
     CDS             complement(9459..10085)
                     /gene="gmk"
                     /locus_tag="VQ873_001254"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3107511.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10215..11828)
                     /locus_tag="VQ873_001255"
     CDS             complement(10215..11828)
                     /locus_tag="VQ873_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3107512.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12171..14918)
                     /locus_tag="VQ873_001256"
     CDS             complement(12171..14918)
                     /locus_tag="VQ873_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3107513.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            complement(15265..16362)
                     /locus_tag="VQ873_001257"
     CDS             complement(15265..16362)
                     /locus_tag="VQ873_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3107514.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(16372..17118)
                     /locus_tag="VQ873_001258"
     CDS             complement(16372..17118)
                     /locus_tag="VQ873_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3107515.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(17221..17574)
                     /gene="rsfS"
                     /locus_tag="VQ873_001259"
     CDS             complement(17221..17574)
                     /gene="rsfS"
                     /locus_tag="VQ873_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3107516.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(17587..18087)
                     /locus_tag="VQ873_001260"
     CDS             complement(17587..18087)
                     /locus_tag="VQ873_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3107517.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            complement(18088..18681)
                     /gene="yqeK"
                     /locus_tag="VQ873_001261"
     CDS             complement(18088..18681)
                     /gene="yqeK"
                     /locus_tag="VQ873_001261"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3107518.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(18681..19310)
                     /locus_tag="VQ873_001262"
     CDS             complement(18681..19310)
                     /locus_tag="VQ873_001262"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3107519.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(19362..19673)
                     /gene="yhbY"
                     /locus_tag="VQ873_001263"
     CDS             complement(19362..19673)
                     /gene="yhbY"
                     /locus_tag="VQ873_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3107520.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(19887..20993)
                     /gene="yqeH"
                     /locus_tag="VQ873_001264"
     CDS             complement(19887..20993)
                     /gene="yqeH"
                     /locus_tag="VQ873_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3107521.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(20996..21586)
                     /locus_tag="VQ873_001265"
     CDS             complement(20996..21586)
                     /locus_tag="VQ873_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3107522.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(21538..22447)
                     /locus_tag="VQ873_001266"
                     /pseudo
     CDS             complement(21538..22447)
                     /locus_tag="VQ873_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            complement(22504..23064)
                     /locus_tag="VQ873_001267"
     CDS             complement(22504..23064)
                     /locus_tag="VQ873_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3107523.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23203..24411
                     /gene="sstT"
                     /locus_tag="VQ873_001268"
                     /pseudo
     CDS             23203..24411
                     /gene="sstT"
                     /locus_tag="VQ873_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24479..25432
                     /locus_tag="VQ873_001269"
     CDS             24479..25432
                     /locus_tag="VQ873_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3107524.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNIAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            25575..25955
                     /locus_tag="VQ873_001270"
     CDS             25575..25955
                     /locus_tag="VQ873_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3107525.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            26054..26275
                     /locus_tag="VQ873_001271"
     CDS             26054..26275
                     /locus_tag="VQ873_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3107526.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            26292..26606
                     /gene="trxA"
                     /locus_tag="VQ873_001272"
     CDS             26292..26606
                     /gene="trxA"
                     /locus_tag="VQ873_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3107527.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT         7451 a         6013 c         4983 g         8232 t
ORIGIN      
        1 tatccaaaga aacaattctc ccttgacttg tgacaatcgc ttgagccttc atagcgtggc
       61 atttcttttt accagaataa ttcgctaatt ctttttttag ggcgattgat ttttacttcc
      121 gtcgcatcaa tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacca
      181 ctttgaacaa gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata
      241 ccaaaatcag ccgcaatttc ttcataagtt cgatattctc gcacatatag aaagcgttgt
      301 taatttattt atctcatttt tcagaaaatt cttttatttc tgtaaaatct acgatactcg
      361 atgtgttttt atataatgat acagtctgag aatcactgtt ccgctagcca ttccaataga
      421 gattaccaaa gccaacatga caaccaaggt cgcacttgcc agtgctttat tatagtcccc
      481 tgtcacaaaa aaggcagttg ttcggtagga gagataacct ggaaccagcg gtgccaaaat
      541 ggccaagata aagaccacag caggtgtctt ataaagaata cttaaaatct ggctgacaca
      601 agaaccaata atggctgcaa tgaaggtagc tacaatgaca ttggtcggtt ccttgagcaa
      661 gagatagatt agccagacag tcatgcccaa aatccctcca ggtaagagca tagaccgttg
      721 cacattgagt acgattaaaa aagtgataat ggcaagaaaa cttgctactg cttgtaataa
      781 aaaggttgtt agtgtcatat tagttcacca ataccaaggc gacagaagtt cctgccccta
      841 aagcgagggt aatgagcagg gattcaaaca tcttactcat accagagttt atgtggttgg
      901 tcataatatc acggaccgca ttggtcaagg caatacctgg tacaaacggc atgaccgcac
      961 cagctataat caaatctgcc gttgaaggaa aacctgtgta gcgagcccaa aactgggcaa
     1021 ttatcccaaa gacaaaggct ccagcaaagg ctgtcacaaa gggaattcgg ataaattttt
     1081 ccacatagag ggaaaaggca aaaccaaata aggtcgccac tcctgcccca agtgcgtcgt
     1141 agatatttcc gctaaacata actgaaaaga aaggagcact aaaggtcgca gccagagtta
     1201 cctgcaactt agtataggga aggggttgag cttgcaaggc cgtcaattgc ttaaaggctg
     1261 tttctaaatc aatctgcccc ccaaccagct gacgagaaat ctggttcaca tcgcagactt
     1321 tttcgatgtt ataagaagag gaggtcacgc gcttcatgcg cgaaatattg gtattttcaa
     1381 tagagaaaaa gatagcggca ggcatggcaa ggacattgca atccacaatc ccctgcgaat
     1441 gcgcgattcg aatcatggta tcttctacac gatggatttc tgagccactt ttaaggagaa
     1501 tagtccccgc tagcataatc acatcaatga cggcatttaa ttcttttgat tcttccatgc
     1561 tttcctcctt ttatcaactc cctctattct atcacaaatc tggactcaaa aaaaatcttt
     1621 gccatgaaat catgacaaag attgattact cattttgatt atccatctac ttttaaggag
     1681 tagctgaagt tgttttaggt ttgtagattg aaatcttgac tctagtctta ttgaggtcta
     1741 ccttttcacc tgctctagga ctttgttcaa caaccatgcc ttctgcacta cctgcaggcg
     1801 ctgtcgtcac ttctacaact tctatattag cttccttaat cccaacaatt tgaatcaaat
     1861 tgttcttagt aaactccaag ctggaaccaa tgtaactcgg catggcaaca cttgtaactt
     1921 ttttagctac tgtcaagaca atttgagtag gtttactcac atcataagtc gttccggcac
     1981 ctggactttg tttcataatc gttcctggtt cgctttcgct ggactcttct tcctctatct
     2041 taatcaaatt ctcaggaacc ttcttctgct tgagttctga gattacttct gtagagttcc
     2101 gtccaatata gttccctaat tgaatcgtcg tagctttttt agctactgtc aaaacaattt
     2161 gagttgcctt gctcaagtca taggtcgtac cttctggtag actttgcttc aggaccgttc
     2221 cagcctcact ctcattcgac tcttcttcct caattttaat caaattatct ggaacttttt
     2281 tctcttttaa ttccgcgata acatcagaag atttccggcc gacataatta ctaatttgga
     2341 aggattgttt gcctgatgag acaaccagat tgattttcgt tccttctttt cgaccagttc
     2401 cagcgccagg atctgtacgg ataatccgcc cttcttccac cttttcacta gcctctgtct
     2461 tctcctcacc aatctcaaaa ttggcttttt tgagcgttgc cttggcctct gcaactgtct
     2521 gacctgccac atctggaatg gcaatggttg caggagttct ggatagtatc caaataagag
     2581 aagctgccac caatacaagg ctggccaaca aaatcaggta acgcatctta aatctatgtt
     2641 ttttcggtgc ttgtggttgg taagtttcct ctgtcacagc ctggcttggg tttttgattg
     2701 atttgtgttc tgtctgcgct tgaaccttag gaatagatgt caaggtactc tgagaaacct
     2761 tcggcaaggt cttggtatct gccttgctcg tttcatcaaa gattaactta ctttcatttc
     2821 tacgattgta ggacaagcta ctagacaagt ccacatacat ctctgaaacc gagcggtagc
     2881 gattggtcaa ctttttagca gttgccttga taataacatt ttctaaagcc tgaggtacag
     2941 atggattttc tgcaataacg gacggcaggg gtttctggaa atgctggagg gcaatggtca
     3001 ccgcgctatc cccgtcataa gggatatggc ctgtcaacat ctcatagaaa ataatcccca
     3061 tggcatagat atcactctgc acagtcgcct tcgaaccacg cgcctgctct ggtgacaagt
     3121 aatgaactga gcccaacatc gagttagtct gggtcagact tgtctctgca aaggctacag
     3181 caatcccaaa gtctgtgacc ttggccgtcc catctggtgt caaaaggata ttttgaggtt
     3241 tcaagtccct gtgaacaatt cctcgagtat gggccaagcg catagccaag agaatttgtc
     3301 ccatgatacg gactgcttct tcattagaaa gaggataatg ttccttgata tagcgtttga
     3361 ggtctagtcc agcaacatac tccattgcaa gatactgttg accgtcttcc tcaccaatat
     3421 ctgttatccg aacgatatga ggatggtcta gatctgccat agctctcgct tcacgctgaa
     3481 aacgagctac agctatcggg tccgtctggt agttggtcct cagaaccttc actgccactt
     3541 cttccccatc taagattaag tctttggcta ggtagacatc cgccatacct cctcgaccaa
     3601 tctgtttgac aatccgatag cgtccggcaa aaatcttgcc gatttggatc attctgcatc
     3661 ctcctcgttc atagaaacaa gggcaaccgt aatgttgtct aaacctcctg cattgttagc
     3721 aaaacgaaca agtgtctccg ttttatctgc taaaggaata tcactggtta caatatcacg
     3781 aatctcactg cctgaaatca tgttggtcaa gccgtcacta ttgagcaaga gatagtcacc
     3841 tgactcaagg ataactgtcc caaaatcagg ctgaatttca tctttttgcc caatagactg
     3901 ggtgataata tttttttgcg gatgagcttc tgcctcttct ggtgtcaatt gaccagcctt
     3961 gagcaattca ttaaccaagg aatgatcgct cgtcaactga tggtattctt ctccacgaat
     4021 caagccgata cgcgaatcac caatatgagc atagatagcc tgattatcaa taatagcaag
     4081 gacttccaaa gtagttccca tgcctctgta agcttcatcc tgaccaagct ggtgaatctt
     4141 ttgattttca atttctaggt aatgggcgaa ccattcacgc acttcattga ctgtatcgat
     4201 ctgggtatca acccaagcta cacccaggtc tgtgaccgcc atttcactag cgatattccc
     4261 tgcacgatga cctcccatcc catcagctaa aataatcatg gtacgtccag ctctattgac
     4321 atagtggttg acatagtctt ggttatttgt tcgtttctga ccaacatctg ttaataatga
     4381 aatttccatg tgtcagttcc ttcctaatcc gatatcttgc gaaattgact gatgaagaat
     4441 ccatcacttc catacaattc aggtgtaatg aggatacagc cgtctttcat gatatcctta
     4501 cattcatgtt ctagttttac ctgctcgaac tcgggatgac tctctaaaaa ggccttaacg
     4561 acttgaaaat tctcctctga gacgatagtg caggtgctat aagttattat accacctttg
     4621 cctagtattt gacaaacact acctaatatt tctaactgaa tttcctgcaa ggacgcgaaa
     4681 tctgccgttt ctttattgta tttgatatct ggttttcggc gcaaaagacc gattcctgaa
     4741 caaggagcat ccaccaaaat cttatcaaag gaatcctggt caaaaaactc atgcaccttt
     4801 ctggcatcca atttttgagt ttgaacccga tcttcaactc ccagacgttg ggcattttct
     4861 tgaattaaat ccaacttgtg gtcgtacaag tccagagcag taacctgacc tgtcgtaaga
     4921 taagaggcta tatgggctgt tttcccacct ggagccgcac aggcatcaag cactcgctca
     4981 tcaccttgta aatcaagcgt cggagcaacc agctgactgg actcatcttg gatggtaatg
     5041 gctccatccg caaacaaatt atgccctgca aaatgccctt gctccttaac cagaccagtg
     5101 gttgctaaaa gggaactatt cgcctccaac aaggcttgga tttcctcttt tcgacttagg
     5161 tctgttacac gaatactagc tttgtttcgc actaacaagc tttcaaagat ggcttttgct
     5221 ctctcctctc cgtattcttc cttgagtttg gtaactagcc aaactgggag agaataggca
     5281 atggagtcac gcttgttttt tcgcttgatg ttagcaatat ctggccagcc ttcacgcaag
     5341 atacggcgaa ggacagcgtt gaccaatttt tcactgcctt ttttacggag tttggccaat
     5401 tccactgctt cattgaccac agcatgatct ggaatcttgt ccaaatagcg gagttggtag
     5461 acactcatga gaagaaggac atagagccag ctgtctaact ggtctctgtc ttcgataaag
     5521 tgggataggt accattccag agtcagttta cgggctaccg ttccatagac tagctcggtc
     5581 actaagccct tgtctgctgc agagagctga ctccccttga ggtgtttatt taaggcgata
     5641 tttgaatatg cttggttcac aaaaacatcc tctagcactg ctagagctaa acttctagcc
     5701 gtttctactt tagtcaccaa atcgttctcc tacagtcaat gtacgtccaa ctccgttgag
     5761 gaaggaagca atgtccatct taggcttacc agctggctgc acttgtttga gggatagagc
     5821 cccttcagcc gttgcgacaa tcaattcttt cttgccgata gagagaatct cacctggatt
     5881 tccctgacct tctactggta gggcttcata aatcttaaag cggtcgccct taaggaaagt
     5941 atgggcaaca ggccaggggt tcattccacg aatttggtta aagagttgac gattggtttt
     6001 gttccagtcc agtttttctt cctctggctt tatatttgga gagaaggtaa cctgactcgt
     6061 atcctgcggt tcaggtttga tatcaccagc aatataggca ggcagagtgt ccaaaagcaa
     6121 atcacgacca actagcgcca atttttcaaa caaggtgcca acattgtcct catctgtgat
     6181 cggaatgctg cgacgagaaa tcatatctcc tgcatccatt tccttaacca tttccatgat
     6241 ggtcacacca gcttcctcat ccccttgaat caaggcataa tggataggcg caccaccacg
     6301 gtgtctagga aggagggagg catgaacgtt gacagcaaag tccatgctat caaggagttt
     6361 gcttgggaga aactgcccaa aagcagcagt cacaattcca tctgctccta gcttcataag
     6421 ttcttccatc tctggacttc cagataattt ttcaggttgg tagatagata gtcctgcttc
     6481 cttggcagcc tgcttgactg gggtttcttg gataactttt ttacgaccaa cagcacggtc
     6541 tggctgggtc acaacggcta gaatttcgta acggtcatct gtcaaaagtc cttttaagac
     6601 tgttgctgaa aagtcggggg tccccataaa gattagtttt gtcatatctt ctccttctta
     6661 taaaaattgc tgcggctcat ggtcaatgct gagacggagc tcactatttt cccgttcttg
     6721 agtcaaggcc aagacctggt tgagggtcgg ccccagctca tcttctaaac ggtatttaat
     6781 taaaatctgg taatgataga ggttgtgggt acgggcaatc ggttttggcg ttggccccag
     6841 aatgggactg gtctctgaca agcctgaccg caaaatgttc atgacttcat aggcacgttt
     6901 gaaaacctct tcttctttct tgtgagaaag ggtaatacca atcgtgaaat agtaaggtgg
     6961 atagccgagt tgtcgtctga ttcccatttc ataggcataa aagccttcgt aatcttgatc
     7021 cttggcaaat cgaatagcat agtgctgcga attgtaggac tgtatcaaga cttgacctgc
     7081 tttttcagcc cgacctgctc gacctgctac ctgagtcaag agctggaagg ttctctcaga
     7141 agaacggaaa tcaggcagat tcaaggccgt atccgcattt agaactccga ctagggtaac
     7201 attgggaaaa tccaaaccct ttgcaatcat ctgagtacca agtaaaatat ccgcttcccc
     7261 tcgcccaaac tggtcaagca aggcttggtg actgcctttc tttcgagtcg tatccacatc
     7321 catcctaaaa atgcgagctt ggggaaagag ttctgctagc tcatcataag ccttctgagt
     7381 tcccgtccca tagtaacgaa tactgtggct cttacagtta ggacagacct gaggaatatc
     7441 cttcgagaaa ccacaataat ggcagttcat agtcttggta tccatatgca aggtcagaga
     7501 aatatcgcag ttgggacaag tatccaccgt cccacactcc cgacacatga caaagctaga
     7561 ataaccacgg cgattgagca tgagaaccac ctgctctttt ttaaccagac ggtcttggat
     7621 agcctctagc aaaggaggcg taaagtttga cgtctcattt tgtccgatat agtctcgaaa
     7681 gtcaatcact tgaacctcag ggattgtagc caaaggattg gcacgttggg ttagacgtaa
     7741 gtgttgatag acgcctttgc cagcacgtgc ccggctctct aagctcggcg ttgcagatcc
     7801 aagtaccaga gttgcttgat tatactgagc ccgtaaaata gctacctctc tggcatggta
     7861 acggggattg ctgtcctgct tataagccgc ttcatgctct tcatcaataa tcatgacacc
     7921 cagatttttc agaggagcaa agatagcaga tctggcacca acaacaactt gggcatcgcc
     7981 acgctccacc ttgcgccatt catcatactt ttcaccattg gataatcctg agtgaagaat
     8041 ggctaccttg tccccaaaac gtgctataaa acgctcggtc atctgaggag tcaaggaaat
     8101 ctcaggtacc agcaaaatag ctgtcttgcc cttatccagg gcaccttgga taatctgcaa
     8161 gtaaacctcg gtcttcccac ttcctgtaat cccttgaagt agaaagggag gttgagaact
     8221 gccaatagaa ctcacaaccg catcacgcgc ctgtctttgt tctggattta actccaaagg
     8281 tctacttgct tcaattcctt caaaataagc agccgagcgt tgaacttcct tttggactat
     8341 ggtaacagca ccttgatcca caaagaagtt gacttgctct cgcgagtagg actctaacaa
     8401 gctagccaag gaagcgctct ctggatgaga cagcagataa tctctcagtt ccaacttttt
     8461 cttggcacgt gtagaaatct caacaccttc taattgggca tggtcaacct cataccaaga
     8521 ctgggtcttg accttctttt gatcgactgc ctgatattcc agaccaagca ggccttttct
     8581 agtcaaacgc atcatttcag cttgcttggc aaggtctagt gaagaaaagg ctagcgaatc
     8641 ttctgaacca aacaggcgta ctcgttcttc ctgactcaag ccttccagag gatagagaat
     8701 cttgtcatag ctagaattca gaaatcctgg aagcatggtc ttgaggatag agattttgta
     8761 ggagaagaca gatttgcgta actcctcagc cagccagagt tgttctggcg tgagaacagg
     8821 agaaaaatcc agcacctctg caatatcttt taaatcttgc tccatctctt ctccatctga
     8881 ttgggactcc aaaccaagaa caatcccttg aatcaggcga ttacccttac caaaaggtac
     8941 atgaacccgc atcccaactt ccagcattcc ctcaaattcc tccggaatcc tgtaactata
     9001 gggctggtcc gtctgcatca aaggcacatc tacgataatc ttagctaggg ccatcttctc
     9061 acctcctcct tgtcagtaca ttcttgcaat agaaaaaata agattgagtc cccccaacct
     9121 taaatttttt caccatcttc tttttcttta gcaatttgct ctttgatttt cttttcttct
     9181 tcttctttgc ggcgtttctc ttcttcgata cggcgacgca ctgcttcacg ttttccttct
     9241 ggatctgggt gaattgtaac gtttcctgat tcgatttctt ctaaagcgcg aagagttgat
     9301 ttttcagact tgaaaccttg agttgctggg gcacctgctt ccaattcgtg ggcacgtttt
     9361 gcttccaaga ttacgagtga atattttgaa ggaaccttgt cgagcaaggt atcaatagag
     9421 ggttttaaca tcatttgctt gtacctattt tctaaatttt atcgggtagt tggagatttt
     9481 ggtaacatct cctgatagtg accaatgaca cgatccacac agaagtgttc tgcttcaatc
     9541 acacatttga cacgttcagc agctaggggc acctgatcgt tgacaatcgc ataatcatac
     9601 tcacgcatga gggcaatttc ttccttggcc ttttcgattc gttgggcaat cacttctgca
     9661 ctatctgttc cacgacctac caagcgatct tgcaattcat ccaaatctgg tggtgtcagg
     9721 aagataaaga cagcatctgg aacctttttc ttgacctgaa gagcaccctg aacttcaatt
     9781 tcaaggaaaa catcgattcc cttgtccaag gtttcattga cataggtcag aggagttcca
     9841 tagtagttgc cgacatattc tgcgtattcc aacatctgtc cttgacgaat cagctcttca
     9901 aattcttcac gagtacggaa gaaatagtca acaccgtcca cttctccagg acgttgtgcg
     9961 cgtgtcgtca tcgatacaga atattgaaat tggttttcag aactctcaaa aatctctctt
    10021 ctaaccgttc cttttccaac ccctgaagga ccagaaaaaa cgattagtaa gcctcggtct
    10081 gccattgtgt ctccttttag tcaatctgtg aaataacatt tctctagaat aatggcaaaa
    10141 agccagatta tcctttacag tctttctatc tagtgtaaca aaaaagcagt aatttttcaa
    10201 ctgctctttc ttatttattt agcataatct actgcacgaa gctcgcgaat cacggttacc
    10261 ttgatatttc ctggataatc gagattgttt tcaattttct tacgaacttt gtgagccaag
    10321 attgtgactt tgtcgtcctt gatttttcct ggattgacca tgatacgaat ttcacgtcct
    10381 gcttgaaggg caaagctagt ttgcactcct tcaaagccgt tagcaatttc ttccaaatca
    10441 tggagacgct tgatgtagct ttcaagagac tcactacgag cacctggacg ggctgcgctc
    10501 aaggcatctg ctgcagcgac gataactgct atcacgctct cagcttcaac atctccgtgg
    10561 tgactagcaa tcgtattcac cacaactggg ggttccttgt acttacgggc caattccata
    10621 ccgatttcaa cgtggctacc ttcaacctca tggtcaatgg ctttcccgat atcgtgaagg
    10681 aatccagcac gacgggcaag agccgcattt tcaccaagtt cgctcgccat gataccagcc
    10741 aacttagcaa cctcaatcga atggcgcaaa acattttgtc catatgaagt acggaactgc
    10801 aaacgtccca taatcttcat caagtctgga tgaaggtttg gcgcaccaat ttcataggca
    10861 gcagcctcac cgtattcacg aatcttattg tcaatctctt gacggttttt ctcaaccaac
    10921 tcttcgatac gagctggatg tatacgacca tctttgagca acatttccat agtcatacgg
    10981 gcaatctcac gacgaatcgg atcaaatcct gacaaggtca ccacttctgg tgtatcgtcg
    11041 ataatcacat cgacccctgt caaactttca aaggtacgaa tgttacgacc ttcacgacca
    11101 ataatgcgtc ccttcatagt atcgtctggc agatgaactg ttgagtttgt tgactccgct
    11161 acatattcac cagcgatacg ttgcatagct tgaaccaaga tatccttggc cattttgtca
    11221 gaacgttcct tgacctcttg ctcagcttcg cgaatgcgac tggcaatctc cctggtcaag
    11281 ttttcctctg tctgagccaa gataatatct cgtgcttctg cctgagacag agcaccaata
    11341 cgctctagtt ctgcttcttt ttgtctttcg acttcctcta attgctcttc acgcgcatca
    11401 aggtttttcg ctctatcaga aatactttgt tctttttgtt caagtgtttg ttctttactc
    11461 gtcaaattgt cgtccttacg gtcaaggcta gtagctctct ctgtcaaacg actttcgatt
    11521 tgtttgagtt cttgacgttc tgatttgaat tcagcgtcca cttcttcacg gtattttctg
    11581 gcttcttctt tggcctccaa tagtgcttct tttttaagag acttgctttc acgtttagct
    11641 tcattaacaa gtaaatccgc ttcacgctca gcttgtccac gtaaattagt tgcttcttgt
    11701 tcagcattta aaagcatcaa ctccgcagct tcctgagatg atttcatctt agctgagatg
    11761 ctgacatatc caatgactaa accaatgatg acggcaaaaa cagcaatcgc aagcgacatg
    11821 atctccatgt ttttacctca ttttattgtt attccgaatg acatacattc ttttacattc
    11881 taccataaaa aagtgatttt cacaaaccta aaatagaata tgttttgggg aaattagtct
    11941 gaattttagg attacacttc cttggttttt taaggagata agtcagtgcc gctatcaaaa
    12001 agttccaccg aatttctacc gctatggatt ttctattgtt gtgccaaata gtgttccact
    12061 agattcaaac attttgcttt caagtctttg aaaattcact ttaggaaatc acagcttatc
    12121 ttcaagatca aatttgtcat aaattaactt ttttatttag ttgtatcaat ttatttctta
    12181 agtattaatt tatcctcatc gaaagctttt aaaatatact cattaatcaa tttattatct
    12241 tcttcatttt ttgaaaaata agttttaata ttattgggag ttctatgttc tagtagacga
    12301 tggataacat catcacttct atcatggaac caggtccaat ctacttcagg ataaagtcct
    12361 cgaatatctt cttcaatatc ttttaaaatc tcaaaatcag aaaaatatcc ttttctactt
    12421 aagttgtata aatctgatac agacttttct cttgggtctg ggaaagtttt aaccccctca
    12481 actcttttat cattaattct tttaatcaaa taatggtaga ttttattttg tatctgagga
    12541 aaatcataga cattataact catcaaatca attactttat ggtaaataat attttctgat
    12601 tcttcataaa cttttagagt atctaaaatg tcatctttaa tatccttttc aaaatactta
    12661 aataagtgac atatcaagtc agaatattct atgatatttt ttatatcatc atttttatat
    12721 tttattctta aaatatctgt attaaatttt tcgagtacta ttattgcagt ttcctgatca
    12781 gttgagcagt attctagtaa ctgtgaatag agcggataca ctgaattata taaagaaaaa
    12841 tttttctcca aaatttcatt taaatgttta tttacaatcc caattatctt agatttcaat
    12901 gaatctttat caataacatc catattatcg aggacaattt taataattct cctaaattcc
    12961 tcgctccaat tataatacag tgtttgatta tttaaaattt ctattacttt ttctatgtca
    13021 atatcatcaa caaggggaag aaaaattagc atatttttaa gctctcgaag attttcatct
    13081 tcagtaattt caagtctttc ttgaagataa gtaattcgat tcaacaagta gtctttcgct
    13141 tcctcagtaa cttttatttt accaaatgaa tagtttctaa aatataaatt tacaacctta
    13201 aaatctatat tcggaagaat taatttaaca tcatccaaat caagattttt aagccaagaa
    13261 gatgttctat cgaaaatact tgagtcaggg tttacatatg aattatcata actgagtaat
    13321 aatatttcta aatatctatt aatgattgat ttataaatct tataatgttc aacacataaa
    13381 caatttaatt ttaaaaagtt ataaagattt tttactgtaa actccgcatt aaatagatga
    13441 ttattagcag accatcctcc tcttctatag ctttcatgct cttcacgaat ttcatcaaat
    13501 aattcattaa tagtttctaa ttttctatat aaaaaattga agttaaggat tgaatctcta
    13561 aaaaattcta taatcttttt ctcatctcct gtaaccgagt taagaatttg ttctgttaat
    13621 tcgcttaatt ctccatcata aagtggctct gcataactag gtgttttttc gtatctatca
    13681 attatttgaa tttgctgaaa attaaattca caaactaaga aattaaaata gtctttctga
    13741 cgaaatgcta tattagctag ttctctaaat tttgcttttg ctaaagaata ttgtttttct
    13801 tcatacaact taaaagcctt acttaagaat cgattcccct ttaaatccct aggctcacca
    13861 atctccatat ctagaaagcg atttaataaa gattttttag ataccataat tcgtaattct
    13921 tcatgaccat caatttcaaa tcttaattga tcatttccaa accagcaata ctcatcatcc
    13981 cagtttaaag cccttttctt taaatcagaa tatctagaaa aatctttcgc atcaataaaa
    14041 ctaagtctat ctaaaaaagc cagttgattc cataaatcat cagcattatt tacatcttga
    14101 cttcggtttt ctgatagaac ctctaaaaaa tcttttgtcc tgcaatacaa tttgttctgt
    14161 ttttctgatg tctcctgacc tagattctct tcattagaga taatgaaaat tccttgcttc
    14221 ttataatact ctcgaatgat catagacggt tcctcgggag tataaaaata agcattttta
    14281 gcatccaatt taaatgtatt ttgaatcatt ctaaaaattg aattaaaagt cgaatcactt
    14341 agagaatacc ccacaaacaa tagagtatga ttcattatca atgactggat taaagtagaa
    14401 atcattggga agttcaaatg atagtctaaa taatcatctt ctttcaaaac aatatttttc
    14461 ttactgaagt caccatgcat tttaatcaag tatctttccg aactcgtata agggatgtct
    14521 ttatcctcag cgactacatt gtactttaac aagccacttt caaattgact ctccagaagt
    14581 gaatcatagt ttgtcgtaat aatatgtttt ggtgcaattt tttctattaa tttatgtaac
    14641 tcatttggtt tactcaatcc cttcttaaag aaaatttctt ctatcttctt tgtgtactga
    14701 tttttcccaa aagtatcata ataatactga gcaattctca gtggactatc tgttctttct
    14761 tctggtatgt tcaattcttt ttttaatgat tgaatcaatt ctccccaagt tggtagatta
    14821 gaattagctg atattcctgc accaacaaac aaaactaagg aattttcttt aatagaattc
    14881 tttatttgag ttatagataa attataattt tcttccatat tttaactatc ctacattagc
    14941 ttgtactaca taaatacaaa ttatccttat aaatcttctt ttttattaca taatcttaaa
    15001 caaaagttta tcatggttta taaatataaa aatttatttg tcttttatat tcaatttatg
    15061 attattaata taaccagttc tcttcattat accacaaaat aacaagcata aagcggattc
    15121 aaagataaag attaaggttc atatactaat tttctttatt gactttttgt cttctgtatt
    15181 agggagttta tcattttcca aaaactttat cttcaatttg ttatctaaaa tttctacaat
    15241 aaaaaagcct acctttcagt agacttagtt tgtttctatt ctaatcggca ctctgccaaa
    15301 attttgctct gctatacttg gctttcctag ttggtaaatc tggtcaacct tttgagtcat
    15361 agcatcccaa ggttctttgc caattcggct gactagattg acctgtcctt tcagagactt
    15421 gagatgttgc ctgccttttt cagtaaatcc aaggacatga atggcttctg gcaagacatt
    15481 ttctctagcc tgtaccaaaa tataggtcaa taggcgtctg acacgcgcct tggtgtaacg
    15541 tttggtagtc actaactcga ccaattcttc cacagactgg gctgttttaa tagcttcttt
    15601 aatgcgcaca gccatttctt gattgacctg atagatggtg gttaggtcgg gatttgacaa
    15661 gatttgatag cggagcaagg gaaaatagtc ttcccagatc accttactgg cctgctcaaa
    15721 tagggcaaca gaaggcataa aacgttctaa gaaatcttgg tccttctgat gttgacggag
    15781 ggctgtcgcc gaggcaaagt ccacatcttt attcacagaa tggtaacctg ccccctgacg
    15841 ctgaatcgga tgcagcttga tatttcgtcc tgcaaccgcc tttgcatagg ccagagcaag
    15901 aacatgattg ggggtattac ctgaaaaatc aagaccagca aattccttcc acatagcttg
    15961 ggttttctgg ggataggaaa gggaatcagg cagatttttc acaaatttct ccatctcagc
    16021 acctttctct gtgtataagt cagcgatttt ctggtaatcc agaacttcct ctgtcccaaa
    16081 aactagacta tcaatgccca agcgatccaa gatatccaca gctccttgac caaagaaatc
    16141 agctgcctga acactgacta aaaagggcaa ttccactacc aagtctgcgc cattttccag
    16201 cgccatctgg gcccttgtcc acttatccac aatagcaggc tctccacgct gcatgaaatt
    16261 ccctgacatg gcaacaattt tcagtccctc tgcctgatcc agcaggtatt tatggccatt
    16321 atgaaaagga ttgaactccg cgataatacc tgttatggtc atgctaatct cctacttctg
    16381 cgccacaaaa aaccaacggg tgctagtttc tgttggctcc ttatcctcaa agtctgcata
    16441 gagtttgaag gacttgaatc cagcctgttc cagcaagatc tcataggtca agatctcata
    16501 ggtcctctcc tcatgtactt catcgtggcg actaaaggaa ccatcagcct ccttgataaa
    16561 gaaagtcagc tcatggacga tggagtgagg aacttcgtcc tcatatgtat cccaaagcat
    16621 ggcaaaatct tccgcatttt catggtagga atagccaggg aatacttcat ctgtctggta
    16681 ggtcgagtgc acgtcaaaga tgaaaactcc ctcttcattc agcgcattgt acacgtcctt
    16741 aaagacgtcc cctacttcca cctcatcctg catatagcag atagagtccg aataacacgt
    16801 gacaaaatcg tatttccctg ccttggacaa attcagcata ttaccttcta taaaagcaat
    16861 cttttgcttg gctgaagttg ctctcttctc cgcaatcttc aacatatccg cactcaagtc
    16921 aagtccagtc acatcaaaac cagcctgaga gaagcgcact gattgaattc ctgtcccaca
    16981 agccaattcc aagagtttct ttctctcctt ggtcttaggc aaatgacgca gagaaaaatt
    17041 cgtccatttg tcgtataaac tatcgtccat gaccgcatca tagaccgccg caaaggtttc
    17101 ataagtcgcc ataatcatga tactaagagc tccatggtaa acaccactag ccctttacct
    17161 ttctatcaat ttttctaaaa taagcaaaga aacccagttg actacaactg agttcatctt
    17221 ctaagcaaga gcttctgaaa tatctactga attcgcctca tgccatagct tctctagatt
    17281 ataatgggca cgcatttctt ctgaaaagat atgcacgaca acagcaccga ggtccagtaa
    17341 gacccagcct ccagctgcat cgccttcgat atggctacct ttaaagcctg cttgagctac
    17401 tttttcacgg atattagctg cgatagcgtc caactgacgg ctattcattg agctagtgat
    17461 gacaaagtag tccgtcacac tagtcaaatc ttgtacatca agtgcgagga tatcctccgc
    17521 acgtttctca tcagccgctt tcacgactag ttctagtaat tctttttcgt tcatttaatc
    17581 ctctttttag aaaatatgtt tgtaatctag aacatctgca aagcactcct cccaaatgtc
    17641 ctcataaaat tcattaatcg tttctgctgg aatgtcatcc ccatcaaagg ttgtgacagc
    17701 accttctgga acaataagct gatagccata ttcaaaggca accttgacag aggtatccac
    17761 acaatattct gtctgcatac cacataaaac taatttttca atcccctgtt tatccaagta
    17821 ttcttttaag ccagtttctt tgaaaatact gttatacttc ttctgaaaga ccttttcagc
    17881 aggttttcga tttaaaagcg cagataactg ccaatcttct gatgtttgag cttcagaatt
    17941 ctcaatatgt tgaacataga taatttcaat attcttgctt ctagcctggt tttgtaaata
    18001 agaaattttt tccaatagac tttttgtctg gaacccagtt tctactaaaa cattctgaac
    18061 atcaatgatt ataaaagccg tcttcattta gtcctctttc aaatagtgca caaaggcgtt
    18121 ataggtttca agggtttggg gatagatggg gaatccctga tgagctagat actccacggt
    18181 acgagctgtt tcgtaggcca ccgccttatt gagcgataga cttgcaatct cacgcgccac
    18241 atctactcca ggaaaggctc gattgtgctc gatatagtct gcgacgtaga tgaccttatc
    18301 taggtctgtc atttgaccag caccgactgt atggacttca atggctcgca ggatttctga
    18361 atcatgcaaa tccaaatctt cctgaatttt gtaaattccg accataccat gccagacatt
    18421 attaccccag tttttgaggt cgaaatctag ctgataacgg tcaatcaagt ctagaaattc
    18481 ctgatctgac aactttttag catagtcatg aagaagacct gctagacttg ctttctcaac
    18541 atctacacca aagcgctgag ctaactccat agcggcacgc tccacaccta gacaatgggt
    18601 tagacgtttc tcaggtagaa gctctgccat tttttccaac aaggcctcac gggagcagtt
    18661 gatatagtct tgataggaca tcagtagagc ccctccttct cgatgtagtc tagcactggc
    18721 tgaggtagga gaaagttggg tttccgacct tgggcaatga agtcccgcac catgctggac
    18781 gagatatcca tgagcggtac gtccacccag ataactggat aggaagtccc tgccttgtag
    18841 cgtggacgct gaacccccac aaactgaacc atgtcaacca gttcatcaat tcggtaccac
    18901 ttaggcagat agtcaaccat gtcggcaccg atgataaagt aataatccgt atctggatgt
    18961 tgctctgtca agattttcat ggtgtcgtag gtgtaggaaa tacccttgcg ctccaactca
    19021 atggtttcaa tgactaggcc gtcaatcccc tcaattgcca actcaagcat cttgagacga
    19081 tggtgttcag ggatggtttc ctttttatca acgtgaggag gttggtattc aggcatgaga
    19141 agaacttgat ccagtcccaa ctgttgccgt acttgatccg caacaatgag atgggcattg
    19201 tgaacagggt taaaattccc ccctaaaatc ccaacttgtt tgcgtttttt ctccttgatt
    19261 tctggctcca actctacctt ggtaaaggga gtcaatagtt cgattgtcat aggctagtcc
    19321 cctttatttc tctataaaaa cagttatttg gagtttcggt cttagatttc tttgactttc
    19381 ttagaaatct tgcgattttc tttcttgcta gattgtttaa acaaaatcaa gatgcgtcct
    19441 attttttgga ctgtatccac accgatttct tcttccaaaa tttcagctac ttcgtggata
    19501 ttttcatctg tgttttgtaa gagagtaacc ttgattaatt cacgcgcatc aagagcttga
    19561 cggacgctgg ttttgatttg gtcgttgagt ccatttttcc cgatttggat gataggtttg
    19621 agggtgtgtg cctggctgtt gaggaaggca cgttgttttg atgttaatga cataattttc
    19681 ttccttgttt ttggatagtt attttaggtg gtgagggacg gtcggaacta attttccaaa
    19741 gatttcatct ttgaaaaatg gatttcctga cctcacaatt gagccttggt ctcaattgtg
    19801 ccccttgcca atctacagat tggcaatcac accacggcaa taactatcgc tatatgagct
    19861 cactttgttc gctcagcgat tttgttttaa ataattgctt ttcgtgtgac gacggcgacg
    19921 ccttctggtg cccagacggc gacttttgct atgcctgtta cacgaatcca gcctaggcct
    19981 gagatgacta ggtctgtctt atctttaatg gtaaagacat gctggactag ccttgggaaa
    20041 tcttcttttt ccttgctatt tggtggtgtc agaagagttc ccaggtgctt atcgtagaaa
    20101 gcactagctc cttcaaactt gctacgatgg agtttgagtt cattatcaaa gaaagcagta
    20161 aatccttgct tttctcctgc tataaagtca aagcgtccca aaccacctaa aaatagggtt
    20221 tgctcaggat taagctgata ggtcttaggc ttgatttcct ttttaggact gacatacttg
    20281 aggtttttgg ccgtcaagta gtgagccatc tggtggcggt ggataattcc cggcgtatcg
    20341 taaatataag atccgtcgtc aagcggaatc tctattttgt ccaaggttgt acctgggaag
    20401 cgtgaagtag tgatgacatt ctgatcaccc gtgatttctt ggataatagc attgattaga
    20461 gttgattttc caacgttggt cacaccgacc acatagacat cgcggccctt acggtagtgt
    20521 tcaatcttgt caatgacttc cttaatggca tgtttatttt gtgctgaagt taggaccaca
    20581 tcgactggac gaagaccttc ttcatgggca cgtttcatga gccactggct aatcttacca
    20641 gacttaactg acttaggaag gatatctttt ttatttccta ccaagaggac atcattgccc
    20701 gagacgaaac gtggtaaacc tgggatgaca gatccattaa aatcaaagat atcaatgaca
    20761 ttgaccacta aggcatcact gtctcccacc tcgtgcaaga gcttgaggaa atcatcgttc
    20821 gtcaactgga catctgtgat ttcattgtag tggcggagac ggaaacagcg ttggcaatag
    20881 acttcgccag tctccaaacc tttttcaagt gccgactggg gggtaaaacc aagaccagct
    20941 ttatctgtcg tctgaatggt tgctccacaa ccaatacaga gaatttcttc catagttaaa
    21001 ttcctttttt atatgtaatc ggtccgtact tttcagtgat ttttctcata acacgacgct
    21061 cacgagttcg gttaatctgc gttttgattg agtcatgttg gaccaagggt ttgactaaaa
    21121 ttgaccgaat ccctgcacgg tgggctgctc gtatatctgt catgagctgg tcgccaacca
    21181 tgaccacttc ctttttgtca tagtggaatt ccttcatagc acggtcaata ccaaatgtga
    21241 agggcttcaa ggcccagtaa acgtaatcaa tcccaaattt ctcaactgct cgttgaacgc
    21301 gttttttggt gttatttgac actacgataa tgccaatacc cgcgtcccga aggtcatgta
    21361 gccattgctt catctctggc gttccatcag ggttgttcca agcaatgagg gtattatcca
    21421 aatcgaccaa aacagccttg attccctgcg cctgcaggct tgggactgtc agatcataga
    21481 ctgcttccac agcaaaatct ggtatataat tttcaatcgc cattctggct ccttttctta
    21541 actttttttc gcaattttcc ttagtaacaa ggataaaaca atccacaaac ctgcactagc
    21601 caaactgata tagagccaag catggggctc atctgttaaa ggtaagggaa cattcattcc
    21661 gaaaaagcct gtcacgactg ccaaaacagc tagcaagact gaaatgatag tcaaggttgt
    21721 caaattgtca ttcagattat tgtttagaat attgttgtaa gaggctgaaa gctgctgtaa
    21781 aatctgagag attaggtctg tcatggatac cagctgatga gcctcaatca tggcatcatc
    21841 aaactgttct ctctcaatct catcaaaact acgatacaag gcatgacctt gaatatgctc
    21901 taacaaaatc cgattttgtt tggcagctgc cgtcagataa accataccag tctccaaatc
    21961 agacagggca aagaggtttt tcttggtagt tcgctggcgc aagaggtcat tgacctcatc
    22021 cctactcttg tccatctgct caatgacagg atagtaggca ttgctgataa tttccagact
    22081 ggcaaagaga aacttataaa tcgaaagcgt gtcatggctc tccagataac gagtcatctg
    22141 ttcaatgaca taggcgttct tggtattact aatggtaatc aggcgacgat gctcgacaat
    22201 aaaggtcatg ggaaaagtct catagtaggc cttgtccttt tttacgtcta ggacattaat
    22261 agataaaggt aaccgtccca ctttcacggt ggtaatccat gtgggcgcgc tcgtttctat
    22321 ccagtgcgta ttcaatggtt tccttgtcca aaccgtaaat ttcagaaagg tcttctagtt
    22381 tattcaactt tcctaggtct aggtctatcc aggtacaacc attgcccaac tgcttttcta
    22441 aaaccatctt ttctccttat taaactccct ctattgtacc acaaattact taaaataaca
    22501 ggtctagtct gtgcgtgaga aattgctaac aactgtgata tttcggttag ggacaaagtg
    22561 aagggcttgc tcctcgctac gaagctgtgt cgtacgaatt cccacactga caaccttacc
    22621 cgatacagta atcggtccat ttgtcagaac gacctcatct cccacatcca gttgacgttc
    22681 aaagaggatg aaaaagccat tgatgacatc agacagaaag ccttgggctc ccataccaat
    22741 cgctacccca gcaataccag ctccagccag caaactagaa actggcaaac ctaaaatcga
    22801 caaaatgcag tagagtaaaa agaaatatag cgtataatta aacacatttt ctagtaaacg
    22861 tgagatggtt ttttggcgtc cgacatcatg acgagacatt tttagagaag gtttgacaat
    22921 tctctgcacc atggtatgaa gcattttttt agcaatataa aatacaatca aaagcagtaa
    22981 aagagaaatg accttggtta gaatattctc gataatggtt gtcacatcta gcttttcaat
    23041 ataagcctga ataaattttt gcatataaaa ctcctttatt tcattatacc atattttcat
    23101 cagtctcatt ctccataaat attcaaaaaa tagacagaaa attcttgatt ttgtctatca
    23161 tttatactat aatcataatc actacacaaa aaggagatta ttatgaaaag aatcattcat
    23221 gcttggaata aggcaagcct tgtcaagcgt atcttgattg gtatgctttg tggggaatcc
    23281 taggactgac ccttcctaat ctctcaggga ttgggctact cggggattta ttcgttggag
    23341 gtctaaaagc tgttgctcct atcctagtct ttgccctcgt tgccaatgcc ctttccaaca
    23401 tcaaaaggga caagatagca atatgaaaac tgttgttttc ttgtatatcc tatgataggg
    23461 actttcgccg ctgctcttgt agctgtacta gcaagtttca tcgtccctat tgaaattacc
    23521 ctaaatagtg ccaatactga aattgcacca ccagatggga ttgggcaggt cctcagcaac
    23581 ctcttgctca aactggttga caacccagtc aacgccctgc ttactgctaa ctatattaga
    23641 atcttatctt gggcagtcat ttttggaatc gctatgagag aagccagtaa aaatagtaaa
    23701 gaattgctaa aaactatcgc tgacgtgact tctaaaattg tcgaatggat catcaatctg
    23761 gctccatttg gaatccttgg tcttgttttt aaaaccattt ctgacaaggg agtcggaagc
    23821 cttgccaact acggtatttt attggttcta ttagtaacga ctatgctttt tgttgcccct
    23881 gtggtcaacc ctttgattgc cttcttcttt atgagacgca atccttaccc tctagtttgg
    23941 aactgcctcc gtgtcagcgg tgtgacagcc tttttcactc gtagttctgc gactaacatt
    24001 cctgtcaaca tgaaactctg ccatgacctt ggactcaacc cagataccta ttctgtttct
    24061 atcccactcg gttctactat caatatggct ggagtagcga ttaccattaa cgttttgacc
    24121 cttgttacag ttaacactct tggaattcct gttgactttg ccacagcctt tgtcctcagt
    24181 gtggtagcag ctatctcagc ctgtgatgct tcaggtattg ccggaggttc cctccttctt
    24241 atcccagttg cttgtagcct tttcggtatt tctaacgata ttgccataca aattgttggg
    24301 gttggttttg tgattggtgt catccaagac tcatgtgaaa cagcccttaa ctcttctaca
    24361 gatgtcctct ttaccgccgt tgccgaatac gcagcaaccc gtaaaaaata actcatcaag
    24421 gcaagcctgc tcatgtcttg tcttttacgc ttttattcta acttattagg aaattcttat
    24481 gtctattagc caacgtacga ccaagctcat cttagctacc tgtcttgcct gcctgcttgc
    24541 ttattttctc aatctttcgt cagcagtttc ggctggaatt atcgctctct tgagcctatc
    24601 tgatacgcgt agaagtactt taaaactggc tcgcaatcgt cttttttcta tgcttctagc
    24661 tctggctatc ggcgttctag cttttcactt gagcggattt catatctgga gtctcggcct
    24721 ctatctggcc ttctacgttc ctttagccta caagatgggc tgggaaattg gcatcacacc
    24781 aagcacggtt ttggttagcc atctcttggt tcaagagtca acctctccag acctcctagt
    24841 caacgaattc cttctctttg ctattggtac aggatttgcc ttgcttgtta atctctatat
    24901 gccttcacga gaagaggaaa tccagcacta ccacacgctg gtggaagaaa agttaaaaga
    24961 tatcctccag cgcttcaaat actatttatc cagaggagac ggacgcaacc gagcacagct
    25021 ggtagcagaa ttagacacgc ttttgaaaga agccctcaga ctggtctatt tggatcactc
    25081 tgaccacctc tttcaccaga ccgactacca tatccactac tttgagatga gacaacgaca
    25141 aagtcgtatc ctgagaaaca tagcccaaca gattaacact tgtcaccttg ccgccagtga
    25201 aagcctgatc ttagcgcaac tcttttcaaa aattgcaggt caactgagcc agaccaatcc
    25261 tgcttctgat ttgctagatg aaattgaacg ttatctggaa gtcttccgga accgcagtct
    25321 gcccaagaca agagaagagt ttgaaacccg cgccactctt cttcaactcc tacgtgaagc
    25381 caaaaccttc atccaagtaa aagttgattt ttaccaaaaa tatagacagt aaaaaagaaa
    25441 accactaaaa aacagagctt gccagtattc ttgaaaagta gtataattat tgcatgcgca
    25501 atcatcttgt gacgcagaga ctgcccgtta atggactttc ttctatttat gactctaaaa
    25561 agaaaggaga cactatgacc tatttggaaa aatggtttga cttcaatcgg cgtcagaaag
    25621 aaattgaaag tctcttggaa gagaccattg cccaacagag cgagcaaagt ctgaccttga
    25681 aagagttcta cctgctctac tatctggact tggctgaaga aaaatctcta cgccagattg
    25741 acctgccaga taagcttcat ctgagcccga gcgcagtttc taggatggtg gctcgcttgg
    25801 aagctaaaaa ttgcggtcta ctcagtcgca tgtgttgcca tcaagataga cgctctagtt
    25861 ttatctgcct gacaaatgat gggcaaaaga cactggcctc gctacaaaag actgtcgaag
    25921 aaagcttgga agcaggtttg gatttcttga tttaagatga ttttaaaaaa agttgcgtgc
    25981 gcaatcattt ttcttgacat tctcttttat aaggagtaaa ataaagttag cattaaacaa
    26041 aggagtttta aatatgattg aaattaccta tatagatgcc agcaagaacg aaagaactgt
    26101 gactttcgag tcttatgaag actttgaacg ttcgcaacaa gcttgcctta tcggcgtcgc
    26161 agactactac cctgtccaaa aattaactta caagggtcat aatttggact accatgggac
    26221 ttatggagat atcttcttct atctcatgaa acaagattta agccaatata actaaaaaaa
    26281 ggagaaatac aatggcaaaa gcaattacag atgcaacatt cgaacaagaa acaaaagacg
    26341 gtttggtctt agtagacttc tgggcaactt ggtgtggtcc atgtcgtatg caaggtccaa
    26401 tcttggacaa attgtctgaa gaactttcag aagatgtctt gaaaatcgtt aaaatggacg
    26461 ttgatgaaaa tccaaacaca gctcgtgctt ttggaatcat gtctattcca actcttctct
    26521 tcaaaaaaga cggccaagtt gtcaaacaag ttgcaggtgt tcacacagca gaacaaatca
    26581 aggccatcat tgctgaattg agctaatcaa acgagagacc aagtactttc tttggtctct
    26641 tttttcttgc tctttgccat ttttcaaaaa atatgctag
//
LOCUS       DAVBOH010000027        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOH010000027 DAVBOH010000000
VERSION     DAVBOH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.027"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ873_001273"
     CDS             complement(15..311)
                     /locus_tag="VQ873_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107528.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ873_001274"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ873_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3107529.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ873_001275"
     CDS             complement(3584..4810)
                     /locus_tag="VQ873_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3107530.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ873_001276"
     CDS             complement(4853..5545)
                     /locus_tag="VQ873_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3107531.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ873_001277"
     CDS             complement(5731..7482)
                     /locus_tag="VQ873_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107532.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ873_001278"
     CDS             complement(7472..9217)
                     /locus_tag="VQ873_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3107533.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ873_001279"
     CDS             complement(9423..9719)
                     /locus_tag="VQ873_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3107534.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ873_001280"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ873_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ873_001281"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ873_001281"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3107535.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ873_001282"
     CDS             11300..11443
                     /locus_tag="VQ873_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3107536.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ873_001283"
     CDS             11443..11682
                     /locus_tag="VQ873_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3107537.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ873_001284"
     CDS             12560..13141
                     /locus_tag="VQ873_001284"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3107538.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ873_001285"
     CDS             13141..14403
                     /locus_tag="VQ873_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3107539.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ873_001286"
     CDS             complement(14490..15356)
                     /locus_tag="VQ873_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3107540.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ873_001287"
     CDS             complement(15343..16113)
                     /locus_tag="VQ873_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3107541.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ873_001288"
     CDS             complement(16139..16993)
                     /locus_tag="VQ873_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3107542.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ873_001289"
     CDS             complement(17150..17554)
                     /locus_tag="VQ873_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3107543.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ873_001290"
     CDS             complement(17624..19105)
                     /locus_tag="VQ873_001290"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3107544.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ873_001291"
     CDS             complement(19124..20302)
                     /locus_tag="VQ873_001291"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3107545.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ873_001292"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ873_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3107546.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ873_001293"
     CDS             complement(21519..22556)
                     /locus_tag="VQ873_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3107547.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ873_001294"
     CDS             complement(22557..22910)
                     /locus_tag="VQ873_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3107548.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ873_001295"
     CDS             complement(23154..24044)
                     /locus_tag="VQ873_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3107549.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ873_001296"
     CDS             24177..24713
                     /locus_tag="VQ873_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3107550.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ873_001297"
     CDS             complement(24879..25685)
                     /locus_tag="VQ873_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3107551.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7803 a         5738 c         4613 g         7860 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacttata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaacgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBOH010000028        25830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOH010000028 DAVBOH010000000
VERSION     DAVBOH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.028"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ873_001298"
     CDS             59..772
                     /locus_tag="VQ873_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3107552.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ873_001299"
     CDS             786..1433
                     /locus_tag="VQ873_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107553.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ873_001300"
     CDS             1571..2224
                     /locus_tag="VQ873_001300"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3107554.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ873_001301"
     CDS             2234..2698
                     /locus_tag="VQ873_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3107555.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ873_001302"
     CDS             2711..3979
                     /locus_tag="VQ873_001302"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3107556.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ873_001303"
     CDS             3993..4253
                     /locus_tag="VQ873_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107557.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ873_001304"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ873_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3107558.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ873_001305"
     CDS             5779..6747
                     /locus_tag="VQ873_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3107559.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ873_001306"
     CDS             6763..7755
                     /locus_tag="VQ873_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3107560.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ873_001307"
     CDS             7973..9016
                     /locus_tag="VQ873_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3107561.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ873_001308"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ873_001308"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3107562.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ873_001309"
     CDS             10829..11818
                     /locus_tag="VQ873_001309"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3107563.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ873_001310"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ873_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3107564.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ873_001311"
     CDS             complement(13455..15005)
                     /locus_tag="VQ873_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3107565.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ873_001312"
     CDS             complement(15021..15800)
                     /locus_tag="VQ873_001312"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3107566.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ873_001313"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ873_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3107567.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ873_001314"
     CDS             complement(16720..18228)
                     /locus_tag="VQ873_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3107568.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ873_001315"
     CDS             complement(18313..18546)
                     /locus_tag="VQ873_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3107569.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDVLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ873_001316"
     CDS             complement(18816..19040)
                     /locus_tag="VQ873_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107570.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ873_001317"
     CDS             complement(19144..20973)
                     /locus_tag="VQ873_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3107571.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ873_001318"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ873_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3107572.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ873_001319"
     CDS             complement(21330..21686)
                     /locus_tag="VQ873_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107573.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ873_001320"
     CDS             complement(21982..22272)
                     /locus_tag="VQ873_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107574.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ873_001321"
     CDS             complement(22262..22627)
                     /locus_tag="VQ873_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107575.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ873_001322"
     CDS             complement(22624..24039)
                     /locus_tag="VQ873_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3107576.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ873_001323"
     CDS             complement(24042..24725)
                     /locus_tag="VQ873_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107577.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..25723)
                     /locus_tag="VQ873_001324"
     CDS             complement(24953..25723)
                     /locus_tag="VQ873_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3107578.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25723..>25830)
                     /locus_tag="VQ873_001325"
     CDS             complement(25723..>25830)
                     /locus_tag="VQ873_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3107579.1"
                     /translation="TNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         7821 a         4827 c         4813 g         8369 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaacat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatact ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatcac catctatgat aacaatattt ccttgaaatt
    25561 ctttctgttt aatccgatga attgtagttt taccggcacc actttgccct ccaagcaaaa
    25621 tcgctatagg ttgcttactg gacttttttc ctcttgtcag tgaacgaaga ttccgtgtta
    25681 gagcatgttt gaattcacta tcagtataat cttggatttc cattaggcta ccatccgttt
    25741 ttcagatatc tctaacatac gttcaattcc atccaaatag ccgctatacc tctctatttc
    25801 atcaaaagtt tctactaaat agatattcgt
//
LOCUS       DAVBOH010000029        25645 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOH010000029 DAVBOH010000000
VERSION     DAVBOH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.029"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..165)
                     /gene="tnpB"
                     /locus_tag="VQ873_001326"
     CDS             complement(<1..165)
                     /gene="tnpB"
                     /locus_tag="VQ873_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3107580.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRF"
     gene            complement(146..331)
                     /locus_tag="VQ873_001327"
     CDS             complement(146..331)
                     /locus_tag="VQ873_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107581.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(635..2197)
                     /gene="guaA"
                     /locus_tag="VQ873_001328"
     CDS             complement(635..2197)
                     /gene="guaA"
                     /locus_tag="VQ873_001328"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3107582.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2339..3037
                     /locus_tag="VQ873_001329"
     CDS             2339..3037
                     /locus_tag="VQ873_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3107583.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3080..3976)
                     /locus_tag="VQ873_001330"
     CDS             complement(3080..3976)
                     /locus_tag="VQ873_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3107584.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3985..4920)
                     /locus_tag="VQ873_001331"
     CDS             complement(3985..4920)
                     /locus_tag="VQ873_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3107585.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4917..5642)
                     /locus_tag="VQ873_001332"
     CDS             complement(4917..5642)
                     /locus_tag="VQ873_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3107586.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5726..6361)
                     /locus_tag="VQ873_001333"
     CDS             complement(5726..6361)
                     /locus_tag="VQ873_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3107587.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6363..7190)
                     /locus_tag="VQ873_001334"
     CDS             complement(6363..7190)
                     /locus_tag="VQ873_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3107588.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7212..7547)
                     /locus_tag="VQ873_001335"
     CDS             complement(7212..7547)
                     /locus_tag="VQ873_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3107589.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7548..8079)
                     /locus_tag="VQ873_001336"
                     /pseudo
     CDS             complement(7548..8079)
                     /locus_tag="VQ873_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8710..9321
                     /locus_tag="VQ873_001337"
     CDS             8710..9321
                     /locus_tag="VQ873_001337"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3107590.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9366..10094
                     /gene="rlmB"
                     /locus_tag="VQ873_001338"
     CDS             9366..10094
                     /gene="rlmB"
                     /locus_tag="VQ873_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3107591.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(10133..11044)
                     /gene="trxB"
                     /locus_tag="VQ873_001339"
     CDS             complement(10133..11044)
                     /gene="trxB"
                     /locus_tag="VQ873_001339"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3107592.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11110..11334)
                     /locus_tag="VQ873_001340"
     CDS             complement(11110..11334)
                     /locus_tag="VQ873_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3107593.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11412..12155)
                     /locus_tag="VQ873_001341"
     CDS             complement(11412..12155)
                     /locus_tag="VQ873_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3107594.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12155..12955)
                     /locus_tag="VQ873_001342"
     CDS             complement(12155..12955)
                     /locus_tag="VQ873_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3107595.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13113..13469)
                     /locus_tag="VQ873_001343"
     CDS             complement(13113..13469)
                     /locus_tag="VQ873_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3107596.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13482..13994)
                     /locus_tag="VQ873_001344"
     CDS             complement(13482..13994)
                     /locus_tag="VQ873_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3107597.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(13994..14488)
                     /locus_tag="VQ873_001345"
     CDS             complement(13994..14488)
                     /locus_tag="VQ873_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107598.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14623..15069
                     /locus_tag="VQ873_001346"
     CDS             14623..15069
                     /locus_tag="VQ873_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3107599.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15066..15713
                     /locus_tag="VQ873_001347"
     CDS             15066..15713
                     /locus_tag="VQ873_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3107600.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15734..16315)
                     /gene="pdxT"
                     /locus_tag="VQ873_001348"
     CDS             complement(15734..16315)
                     /gene="pdxT"
                     /locus_tag="VQ873_001348"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3107601.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16316..17191)
                     /gene="pdxS"
                     /locus_tag="VQ873_001349"
     CDS             complement(16316..17191)
                     /gene="pdxS"
                     /locus_tag="VQ873_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3107602.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17343..18722)
                     /locus_tag="VQ873_001350"
     CDS             complement(17343..18722)
                     /locus_tag="VQ873_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3107603.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19016..19939
                     /locus_tag="VQ873_001351"
     CDS             19016..19939
                     /locus_tag="VQ873_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3107604.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19999..20604
                     /locus_tag="VQ873_001352"
     CDS             19999..20604
                     /locus_tag="VQ873_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3107605.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20623..21867
                     /locus_tag="VQ873_001353"
     CDS             20623..21867
                     /locus_tag="VQ873_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3107606.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22090..22347)
                     /locus_tag="VQ873_001354"
     CDS             complement(22090..22347)
                     /locus_tag="VQ873_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3107607.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22389..24425)
                     /locus_tag="VQ873_001355"
     CDS             complement(22389..24425)
                     /locus_tag="VQ873_001355"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3107608.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24685..25602)
                     /gene="glyQ"
                     /locus_tag="VQ873_001356"
     CDS             complement(24685..25602)
                     /gene="glyQ"
                     /locus_tag="VQ873_001356"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3107609.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         7599 a         5769 c         4668 g         7609 t
ORIGIN      
        1 aaagcggtct ttacgtccac cacaaaagag aaaaacttga ccggagaaag gatctaattc
       61 aaagtgggtt ttaaccagat aagccagtga atcaatgcct tgcctcatat ccgttttccc
      121 acatacgaga tagacctgcc ctaggctaga tagatgaatt gtcatagagc aacaccttat
      181 ccaaaagctg ttctaccatt tcgagattga gagattgaaa aaaacttact tcaagcttgc
      241 caatacgaat tttaagcaga atatcatttc tctttttaga atcaaaagga cgagattgtg
      301 gaatctctac aggaacaata ggttgtggca ttaaaatatc ctccaatagt tttactttac
      361 taatagtata caggaggagc tccatgaatg atagatacct tgttatgacg cgcttaccat
      421 attagaaagt tggctctcta attaaattaa ttctcattat atatatcaaa agaccgcagt
      481 ttgaaaacta cggtctaatt ttttgtccaa atgtaaacca cttggaacta ttattcaatt
      541 tattcttttt agcaaatgtt cccgttttaa tcccagttac agtttttaat cctttgtaac
      601 cgttgatttt acaaagcttt taattttttt gcgattactc ccactcaact gttgcaggtg
      661 gtttacttgt aatatcgtag acgatacggt taacatgatc cacttcattt acgatacgta
      721 ctgagatttt ttgaagtact tcccatggaa ttttggcaaa atcagcagtc ataccatcga
      781 tagaagtgat agcacggatt gcaatcgtgt agtcatacgt acgaccgtca cccataacac
      841 cgactgaacg aacgcctgtg ttaacagtga agtattgcca aatatcgcgg tcaagtccag
      901 ctttagcgat ttcttcacga agaatagcgt ctgattcacg aacggtttca agtttctctt
      961 cagtgatttc acccatgaca cggatagcaa gtcctggtcc tgggaatggt tggcgccata
     1021 cgatatggtc tggcatacca agctctgtac caagagcacg aacttcatcc ttgtaaagag
     1081 tattgagtgg ttcaatcaat tcaaactgca tatcttctgg aagaccaccc acgttgtggt
     1141 gtgacttgat agtttgagct gtatccgtac cagactcgat aacatctgta tataaagtac
     1201 cttgagcaag gaatttcaca tctttgagct tgcttgcttc gtcatcgaat acatagacaa
     1261 actcgttacc gatgatttta cgtttttgtt caggatcaga aacgccagca agtttgtcaa
     1321 ggaaacgttt agcagcgtct gctttgacga tattcaaacc aaacttacca ccgagcatgt
     1381 ccataacttg atcagcttcg cctttacgaa gaagaccgtg gtccacgaag atacagatca
     1441 attgatcgcc aatcgctttt tggagaagaa ccccaacgac agatgagtca acaccacctg
     1501 atagaccaag aaggacacgt ttatcaccga cggtttcacg aatttttttg atctgcatgt
     1561 caatgaaatt atccattgac cagtcacctt tagccttaca aatgttaagg gcaaagttac
     1621 gaaggatatc atttccgtat acagaatgac gaacttctgg gtggaattgg ataccgtaaa
     1681 tgtgtttatc tgggttttcg atggctgcgt atgggcagtc agctgatgta cctgtacgaa
     1741 caaagtcagc aggaatctca gtaaccgcat caccatggct catcaaaaca gtctgttcat
     1801 caggtgttga ttcaaaaagc gctgatggtg tgtgagttag ggttgattga ccgtattcac
     1861 gatttccagc atcacctgca ggaacaactt ttcctccaag tttatgggtc aataactgca
     1921 taccataaca gattcccaaa attggaattc cgagttcgaa gatttctggg tcaatatcaa
     1981 atgaaccatc ttcatataca gaatttggac cacctgatag aataattcct acaggattga
     2041 cttcacgaac ttcagcagct gaaattttat ggctttttag ttctgaaaaa acaccaatat
     2101 cacggatacg gcgtgaaatc agctggttgt actggctacc atagtccaat acgatgattt
     2161 tttctacatc ttgcaaatca gttgaaatgt tgctcatctt tttcctttct caaaagaaat
     2221 atcttttctc aatattctat cacaaataag ggcgaattac caactaaaca aggcgaagtt
     2281 tgactttttc tagtttattg gggtacaata gagaaaagat agaaatgaag tgaaaaatat
     2341 gctacctgct tatatgaaaa tccatgatca gataaaaaag gatattgacg agcaccgttg
     2401 ggctattggt gagaggcttc ccagtgaaag agatttagct gagcagtttg cggtcagtcg
     2461 catgaccctc cgccaagccg tatctctatt agtcgaagaa ggcgtcttag agcgccatgt
     2521 aggaagcggc acctttgttt ccagtactcg agtacaagaa aagatgcgag ggacaaccag
     2581 ttttactgaa attgtcaaat cccaaggtaa agttccctct agccagctca tttcctacaa
     2641 aaaaaccatt cccaatgagc aagaagttgc caagctagga atttttccaa cggacaatat
     2701 tatccgaatg gagcgggtcc gctatgccga ccaagttccc ctagtttatg aagttgcttc
     2761 tattcctgaa aaattcatta aggactttaa aaaagaagaa atcaccagtc atttcttcca
     2821 aaccttgcaa aaacatggct atcgtatcgg caaatctcaa cagaccatct atgctcgcct
     2881 tgctaaagaa aagattgccc actatttgga agttgaaaaa ggacatgcta ttcttggatt
     2941 gacccaggtt tcctacctag aagatggtac tgcttttgaa tacgtaaaaa gtcaatatgt
     3001 aggcgaacgc tttgaatttt atcttgaaaa taattagatt accacgcaaa aactctctgt
     3061 cacggacaaa gagtcttttt tatttttcta agaataaatc tttcaaagaa atcaaagtta
     3121 cagcaaacaa tatcattgcc ataccaagaa aatcaatggg ataaaattgt tcattcatta
     3181 ttaagaaggc aaagaaaatc gccgatattg gctcaattga agccaacaag cttgacttga
     3241 ccggtcctat cagactggct cctttaagga aagctgtata ggcaaagaca gtcccgataa
     3301 ggataatgcc tgcaaacgca aggagaaaat caagactagt cgggatatcg gcctgtagaa
     3361 cccctgtaaa aggaagagcg accaaacctg ctatgaccat tcccacacca atgaccaagc
     3421 tgctccccca ctttttaatc aaggctatgg gtaaaatgat atacagagca taagtaaagg
     3481 cagaaaagag accccagaac agaccagcag gtgtcatgga taactggtcc aactgcccat
     3541 gtgttgcgat caggaaggtt cctccgatgg cgaatatgat ggaaactatc tctcccagtg
     3601 tcggtgccac cctatccttg atacagctat aaattaaaat tccgacagga caaacatact
     3661 gaagcaccgt cgctgttccc gcattggtct cctgaatagc agacagatag gcgaattggt
     3721 tgagaaaaag accaatcaga gcaaaaataa gaagagacag caaactcttt ctatccttta
     3781 aaaagaccag tattttatcc tttgcagtag cataagccaa gagcatgaga attccaccag
     3841 cgattaaaag acgcaagttg gtcaagacca gagccgaaat tccgtgtgcc attaggtatt
     3901 ggccactcgt tcctgacaac ccccaagcaa taccagccac aactgttagt aaagtccctt
     3961 ttaaactatt tgacatgtct ctccttactc ttctttgcga atcaagttca tcacttgatt
     4021 gcggtctaat atccattgag ctctctcgtc cttttcatag gtacgattcg ataggaaaat
     4081 agtggcttct tgcttctgac gattccacat gataaaggta cctgtatagc ccgtatggtc
     4141 tagccaatct ccttccaaat tccatgctaa agaacgttcc ttgtcatcca aaggagaaaa
     4201 attttgactt aagtctcttg caaaatcatc tgctaaatag tgttctaaaa agatttgtaa
     4261 atcctttata gtcgaaaata aaccagcact cccagcatgt ctacccagga gacgagcctt
     4321 gggatcatgc actatgcctg cctctacacc tctaactgtt ggaacagcaa gctcaactga
     4381 cccaaacttg gtttccgtca ttccccaagg tttccagact tgatccttta aaatcacatc
     4441 caaatcttga ttaaaaattc tttccaaaat aaagcccaac agcaaaaaat ggacatccga
     4501 ataaagaaag gctggctgac ttcgtctgtt gagatgaaac atcgcttcct ttaattcagg
     4561 ggctgttaaa agatcacgat taggaataaa aggatcaagg tctgttgcat gagtcaagag
     4621 ctggcgaata gtgatgtctg gataatcact ctcaggtaaa aaatctatta ccagtctatc
     4681 aatatctaat tgacctattt cccacaagaa ggtacaaact gtgccaaccc caacaacctt
     4741 gctgacacta gctaggtcat aaactagtcc tgcctcagtc tgcaagccat gctctgggtc
     4801 actctggcct aaatagaact ctgtccattg attgtcctta aaatacgcaa aagaggctcc
     4861 gggataaatt cctgcctcga tttgttcttc tattttttta ataatcttgg tccacttcat
     4921 acttcttcaa accacaattc aacattattt ctatctttac aaaggaagaa tttttcagac
     4981 ttaggaataa aatattcagt agactcaaac ttctggcgaa gacttgctat gtctaattca
     5041 ttgaccaaga acttgagcat agataagtcc caggtaaccg tattgtccac agtcaaatcc
     5101 tgcccctgag ctggaataaa atcaagggat gccccaattt cagatgattc caagaaactt
     5161 tcgatatcag ttgggagatg taattccata gaaatctcaa atttacttaa agaaattgat
     5221 accaaatctg tttgaaattc aggcttttct cctacttcta ctagacttgc tctgtcatct
     5281 tccgcatgaa tcaaaatcaa atcatcttct ggtgagaaaa tttcaaaagc gtagccattt
     5341 tgacctttat ataatcgatg aatcgaatct gttttagata agattccttc aatttctaag
     5401 ggattttcca ccttgacaat caatctagct agtttttttc ttccctctac cttacgagta
     5461 cgcatactgg gagcttcttc taaaaccagc ttttcaagac ccgtttggtc acctagtgac
     5521 agaaaggccg attcttctaa caaggccttc attccaaggg tttcaatata aaatgtttca
     5581 tttaattttc tattattagc ttttaaagta ggaataatcc gtacaatctg atttacattc
     5641 ataaattcct ccgtcacttt ttattttaaa ggattttaga attttttaca agatattatg
     5701 ctcaaattta acattattta gctatttagt aaagatagtc tttcaaggct tttgacaaag
     5761 cctgataacc agcaatactg aggtgcagtc catcagttgt atattctttt ttgagttggc
     5821 ctgcttggtc tgtcaaacaa tcaaatactg gcacaaattc cacctgcata taggcagatg
     5881 caagctcttg ataggcttga ttccagttct gaattttttc attcgagcgg atatagactg
     5941 cctgctggta ctcctctccc tcattgacag gcaaaatgga aagcaattta atctctgtca
     6001 atggataatc gcgagcaacg gattgaatga tagcttcgag attattgaga gcctcattca
     6061 caggaacatc ctttccgata tcatttgtcc caatcagaag aaaaatttta tctactgctc
     6121 caccatatag atgagcatca aggttctcta gtaacagtcc tgtctgatag ccacgaattc
     6181 ctcgattgac aatcgtcttt gaagtcccaa atagctcctg tagaggataa tactcgacaa
     6241 tggaatcccc aataaaaaga atgtttggtt ctacaacaga aatgtgattt aggtgacgat
     6301 acttagtttg aattttttct tgttccttta ggagccaatt ttctaataac tgtactgcca
     6361 cttcattctc ctttttctaa ccagttttcc aagacttgat aaactcctcc ttggctgttg
     6421 gctggtgcta gagcagtcgc cacagctttg gctttctcat cagcattttc catcgcatag
     6481 gcaattccag ccatttcaag catttcaaca tcattttcac tatcaccaaa agccatgatt
     6541 tcttgggatt tcaagtccca gcgcttgagt aattcctcca agccccatgc tttatgaatc
     6601 ccagcttgga ggatatcaat gcaaccatag ccactggata cagctcggac acggccatca
     6661 aagagagcat tgatttcttc caaaaccgaa ctcaaacgtt cctcaccaac aaccatgctc
     6721 atcttgagca caccaccaaa gaggtcagat gttaattcat ccacaaattg catccgttgg
     6781 tagaattttt caatcatttc tggagtcata aaactttcaa gatctgtaaa aatcgtacct
     6841 tccttgacaa aatcaccctt catccccgtt acaacaaact ggtcctgaca cgctcgaccc
     6901 ttgaaatgag tcaaagcctt gttgacaatg gcgtcatccc atgtctgagc ctgaatcaat
     6961 tcattgtttt caaaaatacg agcgccatta gcaacaacca gaaccactcg atccaccaag
     7021 ggactcagta gttgtctcat gcggtgaatt tcattgcccg tcgcaatgac aaaacgaatg
     7081 cccctttgat ccaactgatc taaaatcttt tccaatcgtg ggagatcaag ctgacctcta
     7141 gcatccagca aggtcccatc catatctgtc gcaattacct taatcatcat ttactttcct
     7201 ctggattcaa gctaatacca cttcaatccc acatgttcat tcatttcttt ataggctgta
     7261 tcaattcgtt ccttagtcgc ttcatctaac tggtcacgat gactgccatc ctctataaaa
     7321 tcttccaaaa tataagtttg gtaatgatac aagggatatc cttctggtga aaaggttccc
     7381 tttggtgttc gattgaccca agtaggatga gctttagctg ttccgatagt tgtttttcca
     7441 tccttcttct tgatggtgac atccatgaga acaccacgtt cagtccactt agcattctct
     7501 tcatctccca tagattcaat ccgttgattg gaaatgaagt tccccattta atagacaatg
     7561 agcttcttat ctccatcttt ttccaccgtt tcagatggtt caacaacgtg aggatgccct
     7621 ccaaagataa tatccgctcc ccaatcgatc atcttgtgat aaagagcttt ttgttcttca
     7681 gttggttcca atcgatactc aacacccatc tgaagcatga taatggtgat atctgcttcc
     7741 ttctctgccc gttcaatttc aaccttcatc ttatcttcgt ttaaatctga aagataacga
     7801 ttatagtctt cctgagaaat atactgctca attccattga aaccatagga ataggctaac
     7861 aatgcaacct tgataccatt cacttcctta atgaccagcg gagcctgaac acgtggttcg
     7921 tgcgtataaa ctccgattgg agtgattcca gctttctcaa taatatcggc cgttgaaata
     7981 actccctcaa gttgaaataa ctccctcaag ttgcgaatcc aaaatatgat tatgagctaa
     8041 atccagcaca tgataacctg cctccttaat agcatccata acttcagcag gagcattaaa
     8101 gagaagataa cccgctaaat aatgatcctt attaatggtt ccttcaaaat caccaatagc
     8161 taaatctgct tgcttgagcc aaggagtcac atactcaaaa ttttcatgaa agtcataggt
     8221 accgtcttct tttttagctg aaaagaaaag tccatcgtgg tagagcaaat ccccgtgggc
     8281 cataattctg gcagtttttt cctcttccta ctcctgagac ttttgcttag tcccctcttg
     8341 agaaatagta tctcgttttt gactagtcaa gggattcctt ggaagctttc aaacaacaag
     8401 accaagccct tcataaaacg aaaagctaaa ccaccctgat ttcgatttta tcttctttgt
     8461 atcttcattc tccctacttt cttatgcaag ccttttcttt ttattatatc acagataagt
     8521 atttctttca caattgaatt gaacttccca tctattttct ataaatccta aatgccataa
     8581 tgctttcaat tcttgtcatt ttgtgatatc atgtagagga aatgaactaa tccacagtgg
     8641 cttatttcaa gtataccact tgggctttgg cagtagctaa ctgcactaaa tataatataa
     8701 ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg ctcacttaat tgatatgaac
     8761 gatattatcc gtgaagggaa tcctactcta cgcgcgattg ctgaggaagt cactttcccc
     8821 ctatctgacc aggaaatcat cctaggcgaa aagatgatgc aattccttaa acattcccaa
     8881 gaccctgtca tggctgaaaa aatgggactc cgcggtggtg ttggactggc tgctccccag
     8941 ttagatatct caaaacgcat tatcgctgtt ttggtaccta atattgttga agaaggcgaa
     9001 actccacagg aagcctacga tttggaagcc attatgtaca atccaaaaat cgtctctcac
     9061 tctgttcaag atgctgctct tggcgaagga gaaggttgcc tgtctgttga ccgtaacgtg
     9121 cctggctatg ttgttcgcca tgcccgcgtt actgttgact actttgacaa agatggagaa
     9181 aaacaccgta tcaaactcaa aggctacaac tccattgttg ttcagcatga aattgaccac
     9241 attaacggta tcatgtttta cgatcgcatc aatgaaaaag acccatttgc agttaaagat
     9301 ggtttactga ttcttgaata aagaaaatcc cgttgcaaga cggggttttg tgttataata
     9361 gaggcatgaa aacaaatgat attgtctatg gcgtccacgc cgttaccgaa gccctccttg
     9421 caaatacagg aaacaaactc tacctccaag aagatctccg aggtaagaat gttgagaaag
     9481 tcaaggaact agctacagaa aagaaggtgt ccatttcttg gacatcaaaa aaatctctct
     9541 ctgagattac tgaaggtgct gttcatcaag gttttgttct acgagtgtct gaatttgcct
     9601 atagcgagct agattacatc cttgcaaaaa cacgccaaga agaaaatcca cttctattga
     9661 ttctagatgg tctaaccgat ccccataatc tgggttctat cttgcgaaca gccgatgcga
     9721 ccaatgtttc aggtgtcatc attcccaagc accgtgctgt cggagtaact cctgtcgttg
     9781 ccaaaacagc cacaggtgct attgaacacg ttccaattgc ccgagtgaca aacctcagtc
     9841 aaaccttaga taaactcaag gatgaaggct tctggacctt tggaacggat atgaacggta
     9901 ctccttgcca caagtggaat acaaaaggga aaatcgccct catcatcgga aatgaaggaa
     9961 aaggcatctc tagcaacatc aaaaaacagg tcgatgaaat gattaccatt ccgatgaatg
    10021 gacatgttca aagcctcaat gccagtgttg ctgcggccat tctcatgtac gaagtttttc
    10081 taaatagact ataaaaaagt ttccagtcat ctgattggaa acttttttat aattaactat
    10141 gttctgtgat aaacttgtag gcttcttgac cagcgatagc tccatctcca actgctgttg
    10201 ttacttggcg aaggtctttc aagcgaacat ctccaactgc aaagataccg tcgactgcag
    10261 tcttcatgtg gctatctgtc acaatccagc ctgcctgatc ttggatattc aattctttaa
    10321 caaaatcgct aagagggtcc aaaccaacat agataaagac accaccgaag gcttgctctg
    10381 tcacttgacc tgttttcaca ttttcaaaaa cgacagattc tactctgttt tcacccttga
    10441 tttccttcac tacagaatcc cagataaagc tgattttttc attcgcaaag gcgcgatctt
    10501 gtaaaacctt ttgggcacga agttggtcac gacggtgaac aatggtaaca gtcttagcaa
    10561 aacgagtcaa gaagagggct tcttcaacag ctgaatctcc accaccaact accaataaat
    10621 cttggtcacg gaagaaagca ccatcacaca cagcacagta agaaacacca cgactgttca
    10681 gttcttcttc tccaggcact cccaaaggac ggtgtttaga accagttgct acgataactg
    10741 tacgtgtttc atatgtttgg tcatcagtca tcactttctt aaaatcacca tggtcttcga
    10801 cattttcaac ataaccataa atgtgctcaa caccaagatt ttcaagtggt tcaaacatct
    10861 tttcagccaa ttcaggtcca ctaatattag cgtatcctgg gtaattttcg atatcagatg
    10921 tattattcat ctgaccacct ggcagaccac cttcaatcaa agctactttt agattgcttc
    10981 gagcagcata caaggccgca gtcatccctg caggtccagc accgataata atagtatcgt
    11041 acatatagat tccttctttc ttgttgtaac tatctttatt ctaactcttt cttgtcaatc
    11101 acgcaaggat tatgccttga aaacaagaat taaactcata accgcaaagg ataatactgg
    11161 gacaaccaag actccaatca taatcatatc atagagatgg gcttggcgag ccctggctgt
    11221 cttatcaact cccgacatgg ctctcagacc aatccaaatc cctaaaaaaa tcagaacaag
    11281 gatggtggtc aagatcaaac tctcgaaata taaagaaaat agttgcagta gcatgatttc
    11341 tctcatttct atctttttta aagagtaaac tcagctagtc caactaactg agttttcctt
    11401 tatctattat atcaaatata agtccgtttg taactagcga agaattcttt tgtccgctct
    11461 tctttagggg tgtggataat ctcatccgga gttccagact cgatgatttt ccccttatct
    11521 aagaagagaa ttttatccgc aacttgggct acaaaggaca tgtcatgact gaccaaaatc
    11581 atggtctgac ctgacttagc agcatctgca atagactttt ctacttcacc gaccaattct
    11641 gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat ctggtttcat agcaagcgca
    11701 cgcgctaggg caacccgttg cttctgtcca cctgataaat ggcgaggata atggttttca
    11761 cggtccgaaa gcccaacctt agccaactct tccttggcaa tcttagtcgc ttcttggtca
    11821 gataatttct tgacaacaac caagccttct ttcacattat caagtgctgt tcgacgttca
    11881 aataaattaa actgttggaa aaccatagac aacttacggc gtagggcaag gatttcttct
    11941 tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct gaatagagcc actgtcaggt
    12001 gtttcaagat aattgagact gcgaagaaag gttgattttc cagctcctga agaaccaatc
    12061 aaggctacaa cttccccttt ttgaatatcc aagttcagat gatccaagac agtctgtcct
    12121 gaaaaggatt tgcttaaatt cgaaatctta atcattaacg aaggtctcct ttcacatctg
    12181 tttgcactgt atcaggtgca gaaatagcca tttttctctc gatgaaacga ccgaggcttt
    12241 caattccgat attgactacc caataaacaa gggcaacaga gatgaagcgt tcaaaatagc
    12301 gataatcagc tccacctaga atctgagctt gggcaaagac ttccacaaca cccgcactaa
    12361 aagctagaga tgttcccttg gtcaaaccga tgagggaatt aatcaaggtt ggagtagcta
    12421 ccaccgctgc attaggaata atcactcgtc gataaacttg cgctcgggtc atacccagac
    12481 tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat ggctgcacga atggtttcac
    12541 tagcataagc tgcctcatta aaggcaaaag cgacaatcgc aaaagctgca gctggaatcg
    12601 cattgatatt gagaccagtt ccccattgct gattgagggc tttcaaagcc aaaggaattc
    12661 cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc ttttaagaaa ctaacaaaga
    12721 aggcctgcaa gggatataaa atcttgacac gattgatctt cacaatggca aaaagaagcg
    12781 ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat aattgttgtt ggaagttgtt
    12841 ggacaattct agggattcca tcaaagaccg aacgtaggct aaacagcttg ccatccggaa
    12901 tcaattgcat caagttttgg taccaatctg atgctaaaat cgttgtaaca ttcataaaaa
    12961 catcctcttc tgataatgat tcattctacc atgcttctgc cgtcaatgaa attatttgct
    13021 acggtcagat acagactttg tctacctact agtttatcat actttgaaac agggaagtta
    13081 tatattttat ctatcaaaga gatagataaa aactatttca gtcccagttc ttcataagat
    13141 tttcgataac cgatttgctt aacagttcca ttttctacta aaatgggccg ttttaacaac
    13201 ataccgtcac ttgctagcaa ctcagccgct tcttggtttg acaaacttcc taccttatct
    13261 tttagcccta attcacggta tttgatacca ctggtgttga aaaattgctt caattcaaat
    13321 cctgaggttt ctagccaatt caaaatgact tcttggctag gtgtttcttc cacgatatgg
    13381 acggctttat agtccacacc taattgattt aattcttgtt ttgctttttt acaagttgaa
    13441 catttggggt attcgataaa ttctaacatg tgcttctcct tctatttgtt tatatcttta
    13501 aaatctacgc cttcatgctc caagagccaa gctttctttt ccactcctgc agcatagcct
    13561 gtcagacgct tgcctgctcc caacacacga tgacaaggta ctaggataga ccaaggattg
    13621 cgtcccactg ctccaccaat tgcttgagca gaagccactt gcaggtcttg agcaatttgt
    13681 ccataggtca ctgtctgacc ataaggaatg ccctgtaaat agtcccaaac tctcttttca
    13741 aaattcgttc cgattggcgc caagagcaag ttggataaat cctgaggctt gcctttaaag
    13801 taatcatcta agcaagcaat aactgggtct aaaataggat gactaacaac ttcttctatc
    13861 gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa
    13921 taatggtcat cagctacaag tgatagaata ccaattggtg aggagtagag gatttttaca
    13981 tacttctttt gcattatttc tttaattttt gataggccaa gcgttcgcca tctactggca
    14041 ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg ttgcataacc ttgttttcag
    14101 catgcgtatc tgagcgaaaa tcaagataat caaaaccttc aatcaagccc tctaagaagg
    14161 tttgagcaac tccttttccc tgcacatctg ctgccacagc aatacggtga aagactagat
    14221 actctgactc tccagcttgc cagtttccct cataaatagc ttcataggcc tcctctggac
    14281 tcttggtcac agcagcatag gctagcagtt ctccctcttc caaggctacg taggcttgcc
    14341 ctgagatgat atcatcgata ataacatctg catttggata gccattttgc cactggttac
    14401 taccagcatc tgctaaacat tttttggcat cctctatcac ctgcatgatg gcatctactt
    14461 catttggaaa agctaaacga atttccatct tttttcctca tttctgacta gtttctccca
    14521 tcatagcata atttaagtct ttctacaagc agttaaaact tgactttgta tttttgttat
    14581 tttataatct agttatcaaa actatataaa aaggagttga aaatgaaaac taccttttcc
    14641 tacccaaaat gggcagaaat tccaaacatt aacctctatc tggaccaggt tttgctctat
    14701 gtcaatcagg tctgcgcccc tatctctcct aataaagaca aaggcctaac agcatctatg
    14761 gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg acaaaaaaaa ataccaacgc
    14821 caacagattg cccgtttgat tgctatcaca accctcaagt ctgtattttc tattcaagaa
    14881 atagcccaga cacttaatac tctacaaact caagcaagtt cagaccaact ctacgatgct
    14941 tttgtggact acatgaacca aggaattgac ccagctaacc ctattatcca aaccagctgc
    15001 caaaccgtta aactctatca tcaaactcta gacttaatcg atcatactca agaggaggta
    15061 atccaatgaa cactagtctt aaactcagca aacaactcag ttttggagag gagattgcta
    15121 atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat cttgctgcct atttcatcca
    15181 tctatagtta tgaagcacac ggatttttat cctctatcgg cgtttccatt ttcgtcatca
    15241 gtctctttct catgttccta tcatccacca tttatcactc tatggcctat ggttcgaccc
    15301 acaaatatgt tttgcgaatc attgaccatt ctatgattta cgttgccatt gccggctcat
    15361 acacgcccgt tgtcttgacc ttgatgaata actggtttgg ctatctgatt attgtcatcc
    15421 aatggggaac gaccatcttt ggtattctct ataaaatctt tgctaaaaag gtcaatgaga
    15481 aatttagcct tgctctttac ctgattatgg gctggttggt tctggctatc attcctgcca
    15541 ttatcagtca aacgacaccc gttttctgga gtctcatggt aactggcggg ctctgttata
    15601 cagttggagc tggattttat gccaagaaaa aaccttattt ccacatgatt tggcatctct
    15661 ttatcctagc tgcgtccgca cttcaataca tcgctattgt ttattacatg taaaaaagtt
    15721 gagaaattca atctcaactt ttttctttac acatattgat aaagtactgg tgcaagcgca
    15781 catcatcagt caattctgga tgaaaagaac ttaccaacat atttttttct tgggctgcaa
    15841 caatttgatt gttcactgtt gctaaaattt ctacaccctc accaacacta ctgataatcg
    15901 gaccacggat aaaggtcatt ggaatcttgc caactccctt acattctgct tccgtgtaga
    15961 aacttcctaa ttggcgccca taagcattac gctcgaccac catatccata gttcctagat
    16021 gactctcttt ctgagaagtg atttccttag ccagcaaaat taagcccgca caggtcccaa
    16081 acactggtaa gccagataga atggcttctc ggatgggaag tagcatgttc tggtcacgta
    16141 agagcttgcc catggttgta gactcaccac caggcaaaat caaacccgac aagtcactct
    16201 gatcttgctg aaaatcatct agatttctga gttctacact ctcgacacct aattgatcta
    16261 gcacttttgc atgttctgca aaggcccctt gcaaggccaa tattccgatt ttcatctatt
    16321 ttcctcgttc agccatgaga atttggattt cattttcatt aataccaacc atggcttctc
    16381 ctaaatcttc agagatttga gctaggattt gaggattacg gaagttagtc acagccttaa
    16441 caatggcact cgctcgttta acaggatctc ctgacttgaa aatacctgaa ccgacaaaga
    16501 ccccctctgc ccctaattgc atcattaacg cagcatctgc tggcgttgca acacctccag
    16561 cagcgaaatt tacaactggc aattttccat gttcatgaac atattggacc aattctacag
    16621 ggacttgcaa atccttggca gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc
    16681 gaatttcctg attcatcata cgcatatgac gaacagcttg gactatatcc cctgtccctg
    16741 gttctccttt ggtacgaatc atggaagcac cttcagcgat acgacgcaag gcttcaccca
    16801 aatccttagc accacagaca aaaggaactt ggaattcttt cttgtccaca tggaaacggt
    16861 catcagctgg agatagaact tcactctcgt cgatataatc aatttcaata gcctctaaaa
    16921 tctgagcttc aacaaaatgc ccgattctga ccttagccat tactggaata ctaaccgctt
    16981 cttggatttc cttaatcatc tttgggtcgc tcatgcggga aactcctcca gctgcacgaa
    17041 tatcagccgg aattcgttcc aaggccatca cagctgccgc accagcagct tctgcgatac
    17101 gagcctgttc aggattctgc acatccataa taacaccacc cttgagcatc tgtgccaagt
    17161 ttttatttag ttcataacga ttttcagtca tttgttttat cctcatcatt tgtattggta
    17221 gctacctttt cattttaagt cagaacagaa tgaagcacaa gataaaaaaa ctataattgt
    17281 atggggacag attagctaaa aactatctga ccttaactta aggccagata gctcattcat
    17341 ttttattttt cagccgtaag ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt
    17401 ggcaagaaga agaggtctgt caatgccaat ttatcaattg tcacatgctc ttggatagca
    17461 agtgagaaca tgtggattcc catgctaatt gcaatatcat gtgaaaccat ttgggcacca
    17521 agaatttcac ggctatcttt gtcaaagaca atcttaattg ctacttcatg gttgtcatgt
    17581 ttcatgaatt ctggtttttg aagatcgtta aagcctgttt cagttgcgtt gtaaccagca
    17641 gctttcgctt tttcaagagt caaaccagtt gaaaccatgt gaagaccgta gattgagata
    17701 ccatttgaac cttgaacacc gattccttcc aattcatgtc cacaagcatt gtaggcacca
    17761 acgataccag tgcgaacagc atttgaagca agagcgatat agcttgtatc tttacgagca
    17821 ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt
    17881 ttcttgtcta caaggaaggc accgttgcgg aagagttcga tcttaccatc tgcaagggct
    17941 gtgtttggac ggaaaccaac tgcaaggata accatatcca cgtcaaagct ttctttgtca
    18001 gtaatcaagc gttcaacttt accgtcacct tcgattgctt taacagtttg acctagagcc
    18061 aagcggatgt tgtgatcttc caagttcttc gccatcattt gtgtgaagtc tttgtcatag
    18121 taaccgttca agacagtatc aacgatatca acaaggacaa cttcttttcc aagacgttca
    18181 aaggcttcag caagttcaac accgatgtaa ccaccaccaa caacggcgat acggtcgagg
    18241 tgttggctct tgtcagaaag tttattgata acttcttcag cattttggta caatttcacg
    18301 aattgtacgt tttcaagagt tgctttaaat tcgcggtttc ctttaacaat ttcaacacct
    18361 tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa tcaatttttc gtatgattct
    18421 ttgtgctctt ttccttcaac ttccgctgta actactttgt tatcatagtc gattgaaaga
    18481 acaggtgagt tcatgtaaac tttagcacct ttagcttcca atttttcttt atcagaatag
    18541 aacaagcctt cagcaccgtc aatttgttca ccaatccaaa gagccattcc acatcctagg
    18601 aaagagatgt tagagttttg gtcaaataca acaatttcgt tctcatttcc aaaattatcc
    18661 aacatggtat tgatacatgc tgtaccagcg tggttagcac cgactacaac gattttactc
    18721 ataaaaattt cctgccttca ttctaaattt accttactag tataccattt accgttagcg
    18781 tttacaaggg gggtactatt atttcagcat tttttatcaa aaataattcc ccatttatcc
    18841 tgttttcaag cctcatgaat tttatgagca tatttcttga ctttttccaa attttgtttg
    18901 tgaaaattct aactttatgg tattataata acatgaaaat gaaatgtaag ggcttcaatt
    18961 tagatgatta tttgatatta caacttattt tctataagag aaaggagttg gtagcttgac
    19021 tcttcgttca cattctgaac ggctaatggg gactactatc actatttcat tagtggatga
    19081 gcaagccgat atctttctcc aaaaatcctt tgacttgctc aaagaacttg aataccgctt
    19141 caacgccaat agtcaagaat ctgagttgat ggaaatcaat tatcaagcag gaatagcccc
    19201 cgtcacggtt catccagacc tgtttgagct gatttcactt gggttagagc atagcctagc
    19261 gctctctagc cacctcaata tcagcattgg tcccttaatt caaacctggc gtatcggttt
    19321 ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg gtgctgcctc taatcaatcc
    19381 tcatggtatc gagttagatt cttctacttc tactgtgttt ttaaaacaga aaggaatgaa
    19441 gatcgatcta ggttgtttag ccaaaggata cagtgcggat aaggttgccc aatttcttag
    19501 gaaagagggg gtgacttctg ccttgatcaa tctgggaggg aatatcctga ccattggaaa
    19561 aaatcaggca agaggggata acccatggca aatcgggatt caagacccag ccaatcctag
    19621 gggaaatcat ttaatgacca tccctgttgt caataaatct gtcgtgactt caggcattta
    19681 tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac atttttgaca gtcaaacagg
    19741 atatcctgtt gaaacggaac tagcgagtct aacaatcatc tctgataaat cagtcgatgg
    19801 cgaaatctgg acgactcgac tctttggaga aagacctgct tctatcctct ggcaagtcga
    19861 aagtttggag ggcatcgaag tcatcctcat cgataaagaa ggccacctaa gctgttcttc
    19921 aggaattcct actctataga gacaactgtt tcaatggaat tttaaaattg tattatgtaa
    19981 aaagagaaag gaaatctcat gttaaaactt attgctattg ttggaacaaa ttcaaaacgt
    20041 tctacaaacc gtcaattgct tcaatacatg caaaaacact tttctgacaa agctgaaatt
    20101 gagcttgttg aaatcaaggc cattcctgtc ttcaacaaac cagctgacaa gcaagtacct
    20161 gctgaaatat tggaaattgc tgctaaaatc gaagaggcag atggcgttat tatcggtact
    20221 cctgagtatg atcactctat tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat
    20281 ggtatttacc cacttttgaa caaaccaatc atgattacag gtgcttctta cggtacgctt
    20341 ggttcatctc gtgcccaatt gcaacttcgt caaatcttga atgctcctga aatcaaggca
    20401 aatgttcttc cagatgaatt cttgctctca cactctcttc aagcatttaa cccaagtggc
    20461 gacttggttg accttgatgt tatcaagaaa ttggatgcca tctttgatga cttccgtatc
    20521 tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat tacttcgcaa agatgctgaa
    20581 gactttgact gggaaaattt gtaagatagg agaccaaaaa gaatgaaatt tgttggactt
    20641 gttggatcaa actacgatca atcatataac cgtaagctct tggaatttat ccgtcgctac
    20701 ttcaaactca aatttgaatt agaagttctt gaaattgacg aagttccaat gtttaaccaa
    20761 gatgaaaaat gggatgaaag tttccaatta cgttatttat ataacaaaat tactcgtgca
    20821 gatggtgtta tcattgctac tcctgagcat aaccacacta tctcagcttc actcaaatct
    20881 gtacttgaat ggctttcata cgaagttcat ccatttgaaa acaagcctgt tatgattgtg
    20941 ggtgcatcat actatgacca aggaacatca cgtgctcaag ttcaccttcg taaaatcctt
    21001 gatgctccag gtgttaatgc ctacacgctt ccaggtaacg aattccttct tggtaaagct
    21061 aaggaagctt ttgataacaa cggaaatatc accaacgaag gcactgttaa attccttgaa
    21121 acttgcttag ataactttgt taaatacgta ggagtcgttt cgaaattgaa aaaaccaaaa
    21181 ccaatcgaat cagaagactt ggattgtgga aaaccaatcg ctacaaccat cacagaagtt
    21241 gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa tcactggtgc tgtttctggt
    21301 gatacctatg tcaaattgga ccacggtatc ctaacagtta accaaattga tatgttcttg
    21361 aaagctatgc catttgaatt gacatacgct gacgacaaca accaattcct ctactacaac
    21421 aacgctcacc aagatccaga cactatgttc gctaaacgtg taccacctca atcaggtagc
    21481 cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta tgaagaacgt agagtgggtt
    21541 atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta cgatcgttcc aggttctcct
    21601 gcaggtgtta tcaacactca caactaccaa gcaatgtact atcctgatgg atcatacgct
    21661 ggtatcaatg aaatcgtctt taacttccaa ccatggcttg actggtacct aaaagagact
    21721 ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg ctgccggagg tcatggagac
    21781 gccgatgcta cttctggcgc ttctgattca ggggatgctg gaggccacgg tggtgacgca
    21841 gacgctacag ccggtgcaag ttactaatga tagtttttag gaaccattat ggttcctttt
    21901 ttagcgaaaa aagactagca aacacaaact gctagtctct ttgttatcgt ttcatctatc
    21961 tttgttaaaa gaaagagtac ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    22021 ccgcaggctg tacttaagta cggcaaggtg aagctgacgt ggtttgaatt tgattttcga
    22081 agagtattat tatgaatttg ggtcatcaag actacggcca tgtaatcctt tttcacgttg
    22141 tacttggcgt agtttttctg gtgtaacatc gtttccttct tcgtccacaa ttttgattcc
    22201 ttcaatgtgg tgacgaacag cgcggcgata accttcgatg tactcctcac gtagtttggc
    22261 ttgttccact ttttcttctg atgttaagcc ttctgttttt ttctttttag caagctcatt
    22321 gatacgagca atttttttcg gatccatttc ttctcctttg taataagata aagtccgttt
    22381 atcaaatttt atttagtgtt aatttggtta aaacaagcaa acttagctgc tttcttggtt
    22441 agttgtgaca agattgccaa acgattttga cggacagcct gatcttcagc cattaccata
    22501 gtattttcaa agaaagcatc aatgactggg ctaagcgcaa agagttgttt caattgctga
    22561 cttgcaggtc ctgataaaac gagtgtttct actgcttctg ccaaagcttt ttcttggtca
    22621 ttctcaaata gtgctgaatc aactgtagca accccttctg ccttctcagc caggttaaag
    22681 gcacgagaaa gtgattcaac agatggttta aaatattctt ccttgcttac ttctacgaga
    22741 gcacttgctg cttccaacat atctgccaca acaaagtttg aacctgcaag aactgcttcc
    22801 ttgatatctt ttggagtaga gcccatcatc ttatcaacac gagccttgat aaagtccata
    22861 acctctgctt tattttcata agtcaaactg tcaaatttca atgcataaag gctatcaatc
    22921 agctcatcca tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac accttgagtt
    22981 gcacgacgaa gggcataagg gtcattagaa cctgatggaa tcaatcctac tgagaagaaa
    23041 ctcaaaatcg tatccaattt gtctgcaatg gctagaactg cgccgacctt gctctctgga
    23101 agttctcctt cagctgatgt aggcatgtag tgttcacgaa tagcagctgc caccgctgga
    23161 gtttcaccag caagaagggt gtatttttca cccataattc cttggagttc gtcaaattca
    23221 ccaaccatac ctgtcaataa gtcaaacttg taaatggctg ctgcacgagc aaggtcaact
    23281 gtttcatcca ctgacaaacc agctttttct gccaaaagta cagtgatttg acccgtacga
    23341 atcatgtgtt cacgaaggga accaatcttc tcatggaagg tgacattgtt taatttttca
    23401 acaagatctg aaatcaccaa tttttggtct tcacgccaga agaattctcc gtcttccaag
    23461 cgggctacca agactttttc atttccttta atgacatttt tcaaacgctc tgcgtttccg
    23521 ttacgaacag aaatgaagtt tggcaagagt tttccatctt gatcacgaac aacaaagtaa
    23581 cgctggtgtt ccttcataga agtcaccaag acttcttctg gaacttcaag gtatttagca
    23641 tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat tcaagacttc attcagcaaa
    23701 tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa tttccttgat ttggtcaaca
    23761 atcatttgct cacgttcaca tggatctgcg attacaaact gcttacgaag gtcttcttca
    23821 tagctcaatg ctgactgaat tttggtttct ttccccaaga aacgatggcc acggctcaca
    23881 cgacttccct tgatatcaag gaaatccaag tcaaactctt gctcatccaa gagaacagtt
    23941 aaagtgtgga caggacgaat gtattcaaag ctatttccag cccagtgcat gctgacaggg
    24001 aaagtcaatg acttcaagac atctacaaca ccaggaacaa tggcttcaac tgcttgacca
    24061 acttcttcct tagtgacata gacatattct tcacccttga tttcacggaa ttcgatatct
    24121 tcaacagtca agccttttcc acggacaaat ccttgagctg ctttggtaaa gtttccatca
    24181 ctatccaagg caattttctt tgctggtccc ttgaaatctt ctgtcaaatc agactgtttg
    24241 tctgataaac cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt ttgaatggct
    24301 tcaaaagaca ggcggttttc cttgaggaag gctgccattt tttcgcctag ttgtttttca
    24361 cttggtgtga caacataggc tggtaattct tcaagaccga gttctactaa taagtttttt
    24421 gtcatgtttt ttcctttaca ttttcttcaa tcttttttga tatgcacctt aggtactggg
    24481 gacgtcgcta actaactctg tgagtctgta tggaaatcca atgctaaatt tatcaagatt
    24541 tccaacaatc tcatcaaagt ggatttagct gactgatttt tgaacctaag gtttcaaaaa
    24601 tccccacata acagtacggc ggtgcatatc cctctagcaa gtcttcgact tgcctctaac
    24661 gattttagag tacagtatta ctcactattc tgcgtcttct gctaaaagtt taactcgtgt
    24721 ttcttcatcc aaaagtgggt aacctaggcg tttgcgttct gcaacaaagg ttttggctac
    24781 aacacgggcc aagttacgga tacgagcgat atagcctgca cgctctgtta cagatacggc
    24841 accacgcgcg tcaagcagat taaaggtatg tgaacatttg agaacatagt cataggcagg
    24901 gtgtaccaag ccttcttcta atgcacgacc agcttctttt tcaaacttat caaagttttc
    24961 aagcaaaatt tcttggtccg aaatttcaaa tgaatatttt gagtgctcat actcaggctg
    25021 gataaagatt tctccgtatt ttacaccatc agcccactcg atatcataga cagagtctac
    25081 ttcttgaatg taagaagcca agcgctccaa accataggta acttccgcag tcacagggcc
    25141 agttgccaat ccaccgactt gttggaaata agtgaactga gtgatttcca ttccgtcaag
    25201 ccaaacttcc caaccaagac cagctgaacc agttgatggg ttttcccagt tgtcctcaac
    25261 aaaacgaata tcgtgctcca aaggattgat tcccaatttt tccaaagact caaggtaaag
    25321 ttcttggata tttgatggag aaggcttcat gaccacctgg aattggtggt gttggtagag
    25381 acggttaggg ttttccccat aacgaccgtc agcaggacga cgtgatggct ctacataagc
    25441 tgcattccat ggctcaggtc cgatagcacg aaggaaagtg taaggactca ttgtccccgc
    25501 acctttttca ttgtcataag cctgcataag catacaacct tggtcattcc aaaattgttg
    25561 caaagtcaaa ataatttctt gaaatgttaa tttcttagac attgtttact ccttaataaa
    25621 aaatgatttc ttgcgacacg agtct
//
LOCUS       DAVBOH010000030        24519 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOH010000030 DAVBOH010000000
VERSION     DAVBOH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.030"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ873_001357"
     CDS             complement(98..2356)
                     /locus_tag="VQ873_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3107610.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ873_001358"
     CDS             complement(2585..2815)
                     /locus_tag="VQ873_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3107611.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ873_001359"
     CDS             3005..3688
                     /locus_tag="VQ873_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3107612.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ873_001360"
     CDS             3688..4422
                     /locus_tag="VQ873_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3107613.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ873_001361"
     CDS             4576..5433
                     /locus_tag="VQ873_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3107614.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ873_001362"
     CDS             5575..6447
                     /locus_tag="VQ873_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3107615.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ873_001363"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ873_001363"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3107616.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ873_001364"
     CDS             7426..8637
                     /locus_tag="VQ873_001364"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3107617.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ873_001365"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ873_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ873_001366"
     CDS             9197..10006
                     /locus_tag="VQ873_001366"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3107618.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ873_001367"
     CDS             10482..11213
                     /locus_tag="VQ873_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107619.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ873_001368"
     CDS             11259..11462
                     /locus_tag="VQ873_001368"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3107620.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ873_001369"
     CDS             11487..11999
                     /locus_tag="VQ873_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3107621.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ873_001370"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ873_001370"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3107622.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ873_001371"
     CDS             complement(13390..13914)
                     /locus_tag="VQ873_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3107623.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ873_001372"
     CDS             complement(13967..14203)
                     /locus_tag="VQ873_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3107624.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ873_001373"
     CDS             complement(14271..15191)
                     /locus_tag="VQ873_001373"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3107625.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ873_001374"
     CDS             15389..15793
                     /locus_tag="VQ873_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107626.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ873_001375"
     CDS             16009..16590
                     /locus_tag="VQ873_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3107627.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ873_001376"
     CDS             16587..17864
                     /locus_tag="VQ873_001376"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3107628.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ873_001377"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ873_001377"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3107629.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ873_001378"
     CDS             18531..18920
                     /locus_tag="VQ873_001378"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3107630.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ873_001379"
     CDS             19011..20063
                     /locus_tag="VQ873_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3107631.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ873_001380"
     CDS             20207..21742
                     /locus_tag="VQ873_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107632.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ873_001381"
     CDS             21735..22793
                     /locus_tag="VQ873_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107633.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ873_001382"
     CDS             22796..23752
                     /locus_tag="VQ873_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107634.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23837..24519
                     /locus_tag="VQ873_001383"
                     /pseudo
     CDS             23837..24519
                     /locus_tag="VQ873_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7182 a         4406 c         5573 g         7358 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag
    17461 ttcaccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt caaaacatct actggctttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa
    18421 ggccgccggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagctaaag acggaagtgt ttacacggga gtgaatattg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aactaactta tgatgataaa gttcagatct atgaacttag
    23881 aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca attctaatct
    23941 taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa
    24001 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggcta
    24061 gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaactg
    24121 gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaccaagag ggagagtacc
    24181 taaaatggga cgtaagccaa gaacgagacc tgaagagagg acagaattag aacgtcttca
    24241 agcagaaaat gagtacctga gagcggagaa tgccatccta aaaaagttaa gagaactccg
    24301 attgaaggag gaaaaagaga aagaagaaag atagaaattg ttcaagaatt aatgactgag
    24361 ttttcgttag atcttcttct aaaagccatt aaactagctc gttggaccta ctactatcac
    24421 ttgaaacagt tagacaaacc agataaggac caagagctta aagctgaaat tcaattcatt
    24481 tttatcgaac acaagggaaa ttatacttat cgccgggtt
//
LOCUS       DAVBOH010000031        22288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOH010000031 DAVBOH010000000
VERSION     DAVBOH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.031"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(287..574)
                     /locus_tag="VQ873_001384"
     CDS             complement(287..574)
                     /locus_tag="VQ873_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107635.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(584..994)
                     /locus_tag="VQ873_001385"
     CDS             complement(584..994)
                     /locus_tag="VQ873_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3107636.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1062..1793
                     /locus_tag="VQ873_001386"
     CDS             1062..1793
                     /locus_tag="VQ873_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107637.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1790..2839
                     /locus_tag="VQ873_001387"
     CDS             1790..2839
                     /locus_tag="VQ873_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107638.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPMDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(3007..3336)
                     /locus_tag="VQ873_001388"
     CDS             complement(3007..3336)
                     /locus_tag="VQ873_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3107639.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3613..3951
                     /locus_tag="VQ873_001389"
     CDS             3613..3951
                     /locus_tag="VQ873_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107640.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3956..4693
                     /locus_tag="VQ873_001390"
     CDS             3956..4693
                     /locus_tag="VQ873_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107641.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4707..6047
                     /locus_tag="VQ873_001391"
     CDS             4707..6047
                     /locus_tag="VQ873_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3107642.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ873_001392"
     CDS             complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ873_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3107643.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6303..7664)
                     /locus_tag="VQ873_001393"
     CDS             complement(6303..7664)
                     /locus_tag="VQ873_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3107644.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ873_001394"
     CDS             complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ873_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3107645.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10110..10364
                     /gene="blpM"
                     /locus_tag="VQ873_001395"
     CDS             10110..10364
                     /gene="blpM"
                     /locus_tag="VQ873_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3107646.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10380..10583
                     /gene="blpN"
                     /locus_tag="VQ873_001396"
     CDS             10380..10583
                     /gene="blpN"
                     /locus_tag="VQ873_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3107647.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10827..10976
                     /gene="blpO"
                     /locus_tag="VQ873_001397"
     CDS             10827..10976
                     /gene="blpO"
                     /locus_tag="VQ873_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3107648.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11080..11199
                     /locus_tag="VQ873_001398"
     CDS             11080..11199
                     /locus_tag="VQ873_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3107649.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11667..12038
                     /locus_tag="VQ873_001399"
     CDS             11667..12038
                     /locus_tag="VQ873_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107650.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12667..13050
                     /locus_tag="VQ873_001400"
     CDS             12667..13050
                     /locus_tag="VQ873_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3107651.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13102..13791
                     /locus_tag="VQ873_001401"
     CDS             13102..13791
                     /locus_tag="VQ873_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107652.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13833..14066
                     /locus_tag="VQ873_001402"
     CDS             13833..14066
                     /locus_tag="VQ873_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107653.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14217..14828
                     /locus_tag="VQ873_001403"
     CDS             14217..14828
                     /locus_tag="VQ873_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107654.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14989..15783
                     /locus_tag="VQ873_001404"
     CDS             14989..15783
                     /locus_tag="VQ873_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3107655.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15780..16415
                     /gene="trmB"
                     /locus_tag="VQ873_001405"
     CDS             15780..16415
                     /gene="trmB"
                     /locus_tag="VQ873_001405"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3107656.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16541..17020
                     /gene="rimP"
                     /locus_tag="VQ873_001406"
     CDS             16541..17020
                     /gene="rimP"
                     /locus_tag="VQ873_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3107657.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17064..18200
                     /gene="nusA"
                     /locus_tag="VQ873_001407"
     CDS             17064..18200
                     /gene="nusA"
                     /locus_tag="VQ873_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3107658.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18222..18515
                     /locus_tag="VQ873_001408"
     CDS             18222..18515
                     /locus_tag="VQ873_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3107659.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18508..18807
                     /locus_tag="VQ873_001409"
     CDS             18508..18807
                     /locus_tag="VQ873_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3107660.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18824..21616
                     /gene="infB"
                     /locus_tag="VQ873_001410"
     CDS             18824..21616
                     /gene="infB"
                     /locus_tag="VQ873_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3107661.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ873_001411"
     CDS             21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ873_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3107662.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         6578 a         3871 c         4884 g         6955 t
ORIGIN      
        1 tgttttgagc tgacttcgtc agttctatcc acaaccttaa aacggtgttt tgagcagtct
       61 gtgcctagct ttctagtttg ctttttgatt tttattgagt atgagttacc taaattatga
      121 tgcatagttg atgggatata tataatagat tgaaatagaa tatgaacaaa ttgataagag
      181 gattttaaag taatctctaa caatgcttta gaaactatag tgtgctattc taaattcaat
      241 tcactataac ttgtttacgt tttaaaaaag agccgggggg ctctttttac ttatcttcag
      301 ttccctgcat ttcttttatc acagctagtc tagtctggat atccttttcc aagaccttaa
      361 acttgtaagt caagtcttct tggtattcct tgataagttc tttttgctgg ttaatgattt
      421 gcaggctgtt ttggataata tccacatcgt ccttgatagc ttgaacgcgg tcagtggtat
      481 tcaagacttc atctgtgatg gtttggcgat tttttgtaac cagataactt ccggctgcag
      541 ctcctgcaaa tagcagtagg ttggataatt tcatagcaac tccttaagcg tttttgatgg
      601 tttcagcgac ttgagcaagt ttgtcaaagt ctggttcgtg ggcgataaaa tcaatcttga
      661 ggtcatcgtc agcactgtag cgaggcacaa ggtgaacgtg agtatgaaaa actgtttgac
      721 cagcgacttc ttcacagttg gaaatgatat tcataccagc agccttagtg actttcatga
      781 ctttttgagc tacttttggt acttgggcaa agagttggct ggcgctcgta gcatccatct
      841 ccaaaagatt gcgatagtgt tcttttggca cgaccaaggt gtgtcctagt gttacttgag
      901 agatatcaag aaaggcaagg acctgctcat cttcatatac ttttgaagca ggaatttccc
      961 ctgcgatgat tttacaaaaa atgcaatctg acataaaatc tacctctact gtactgaatt
     1021 ttgatataat atagctacat tataccagat ttggagaaaa tatgttagaa attaaaaacc
     1081 tgacaggtgg ctatgttcat gttcctgttt tgaaagatgt gtcctttact gttgaaagtg
     1141 ggcagttggt cggtttgatt ggtctcaatg gtgctgggaa atcaacgacg atcaatgaga
     1201 ttatcggtct gttggcacct tatagtggct ccatcaatat caatggcctg actctgcaag
     1261 gagatgcgac tagctaccgc aagcagattg gctacattcc tgagacgcct agtctgtatg
     1321 aggaattgac cctcagagag catatcgaaa cggttgctat ggcttacggt attgagcaaa
     1381 aagtggcttt cgaacgagta gagcccttgt taaaaatgtt ccgtttggaa cagaaattag
     1441 actggttccc tgttcatttt tcaaaaggga tgaagcagaa ggtcatgatt atctgtgctt
     1501 ttgtggtgga tccaagtctt ttcatcgtgg atgagccttt ccttggtctt gatccgctgg
     1561 ctatttctga tttgattcag cttttggaag tggagaagca aaagggcaag tctattctca
     1621 tgagtaccca cgtgctggat tcggcggaga agatgtgtga tgcctttgtc attcttcaca
     1681 agggagaggt gcgtgccaaa ggcaatctcc tgcaactacg tgaagccttt gatatgcctg
     1741 aggctagttt gaatgatatt tacttggctc tgaccaaaga ggaggatcta tgaaagactt
     1801 gtttttaaag agaaagcagg cctttcgtaa ggagtgtctt ggttatctgc gctatgtgct
     1861 caatgaccac tttgtcttgt tcctgcttgt cctgttgggc tttctagcct accagtacag
     1921 tcaactctta caacattttc ctgaaaatca ttggcctatc cttttgtttg taggaattac
     1981 gtctgtttta cttttacttt ggggaggaat tgccacctat atggaggctc cagacaagct
     2041 ctttctctta gttggagaag aggaaatcaa gctccatctc aagcgtcaaa ctggcatttc
     2101 cctagtcttt tggctctttg tacagaccct tttcttgctg ttatttgcgc ccttgttttt
     2161 agcaatgggt tatggcttgc cagtttttct gctctatgtg cttttattgg gggtaggaaa
     2221 atatttccac tttcgtcaaa aggccagcaa atttttcact gaaactggac tggactggga
     2281 ctatcttatt tctcaagaaa gcaagcgtaa gcaagtcttg cttcgtttct ttgccctctt
     2341 tacgcaggtc aagggaattt caaacagtgt caagcgtcgt gcctatctgg actttatctt
     2401 aaaggctgtt cagaaggtgc ctgggaagat ttggcaaaat ctctatctgc gttcttatct
     2461 gcgaaatggc gacctctttg ctctcagtct tcgtcttctc ttactttccg tactggcgca
     2521 ggtttttatc gagcaagctt ggattgcgac agcagtggta gttctcttta actacctctt
     2581 gctcttccag ttgctggccc tctatcatgc ctttgactac cagtatttga cccaactctt
     2641 tccgatggac aaggggcaaa aggaaaaagg cttacaggag gtagttcgag gattgaccag
     2701 ttttgtttta cttgtggaag tagttgttgg gttgattacc ttccaagaaa aactagccct
     2761 tctagcctta ctaggagctg gtttggtttt actagtcttg tatttgcctt atcaggtaaa
     2821 acgtcagatg caggactaac attgctgata cgacactaaa aaagaagttg agttcagtct
     2881 gtctcaactt cttttttgtt actacaggat aatggttggt ccgtagagac ttatactctt
     2941 cgaaaatctc ttcaaaccac gtcagcgtcg tcttaccgta ctcaagtaca gcttgcggct
     3001 agcttcctag tttgctcttt gattctcatt gagtattaac ttggtcttga cttggtcaaa
     3061 gtggaagcgg tcataggccc gccaagcggc gcgagttgga gcatctggat caagagcgct
     3121 gagtcccatg agaagactgg aagtctggta aaatttttcc aattcaatca agaatcgatt
     3181 atccactgtt tcagccttgg ctagaaaacc aagaatagag tttaattgct cctgaaagcg
     3241 gacgtcgtca gcggttgcct gtttgcatgc ttgataggct ttgtttaagt cagtaatcaa
     3301 agtctgagct cttttgatag ggtctgtatc tgtcatgaga attcctcctc taatctgggt
     3361 gccagtcttg attctagcaa ctgtgttttg atactgtcag tctatcactt ttatctcctt
     3421 tttcgccttt aaatctttaa ttgtcattga aatgtcttga attgcgctga gtgaatttta
     3481 tgataaaata gtggtaagct catcatgata ttgtagaaaa ataattcttt taggagcttt
     3541 caaagactgt ttaggattgg gtgtgcttgt gttagatttt ttctgttatt cttttcttag
     3601 gaggagaatc caatgaaaca tatgattatt cagacacaga aaacagtcta taaagtaaac
     3661 gtcgacgatg tctactatat ccaaacacat ccaactaaag cccatactgt aaagattgtt
     3721 acagaagagg ctagttttaa tatggttcaa aatttaagta atcttgagaa ccaatatggg
     3781 gaaaccttga tgagatgtca tcgaaattgt ttggtcaatc ttgataaagt aaaatcgatt
     3841 gattttcaag aaagaatcct ttttcttgga gaagaaggtc aatacgctgt caagtatgcc
     3901 agacgtcgct atagagaaat tcgtcaaaaa tggttgaaag aaggagagta agaagatgag
     3961 aatatttgtt ttagaagatg atttttccca acagactaga attgaaacga cgattgagaa
     4021 actcttgaag gaacatcata tcactctgag ttcttttgaa gtttttggta agccagatca
     4081 attgctggca gaggtgcatg agaagggggc ccatcagcta ttctttttgg atattgagat
     4141 tcgaaatgag gagatgaagg gtctggaagt ggctagaaag attcgggatc gggatccgta
     4201 tgccctgatt gtctttgtga cgactcactc ggagtttatg cccctgtcct ttcgctacca
     4261 agtgtctgct ctggattata ttgataaggc cctttcggca gaggagtttg aatctcgtat
     4321 cgagacagcc ctcctctatg ccaatggtca agacagtaaa agtctagcgg aagattgctt
     4381 ttactttaaa tcaaaatttg ctcaattcca gtatcctttt aaagaggttt actatctcga
     4441 aacgtccaca agaccccatc gtgttattct ctataccaag acagacaggc tggaatttac
     4501 agcgagtcta gaggaggttc tcaagcagga gcctcgtctc ttgcagtgcc atcgctcttt
     4561 tctcatcaat cctgccaatg tggtgcattt agataagaaa gaaaaactgc ttttctttcc
     4621 caatggtgga agttgtctaa tcgcgcgtta taaggtcagg gaagtgtctg aggctattaa
     4681 taacttacac tgagctagga gagtttatga atgttgcttg gatattgttg tatacacttg
     4741 ttactcacgg attaaaaatt gtcatattct ttaaggtaga tggaattagt ctcacttttg
     4801 agaggatttt taaggccttt ctttttaaga tactgttggc cgttgttttt ggaatgcttg
     4861 gctatatggt aggaaatgtt tacctatctt attttatgga acccttgtac ggcataggct
     4921 tatctttctt attgttaaga gaacttccta aaaaactcct tctcttttat ggtctctttc
     4981 caatgatatt agtgaatctc ttttatagag gtgtttccta ttttgtgctt ccatttttgg
     5041 gacaagggca agtatatgat gactactcat ttatttggtt atgtataata attttcaatt
     5101 tcttcatttc tctagctttt ttgaaatggt tggactatga tttcactagc ttgagaaagg
     5161 ggattctcga taaagatttt caaaagtccc tgactcagat taactggata atgggggctt
     5221 actatttggt gatacaaaat ctgtcttact ttgaatatga acaggggatt caatcaacga
     5281 ctgttcgcca tctcatccta gtcttttacc tgctcttttt tatggggatt atcaagaaat
     5341 tggataccta tttgaaggac aaactccatg agagactgaa ccaagagcag gacttgcgct
     5401 acagagagat ggagcggtat agtcggcata tagaggagct ttataaggaa gtacggagtt
     5461 ttcgccatga ctacaccaac ctcttgacta gcttacgtct gggcattgaa gaggaggata
     5521 tggagcagat aaaagagatc tacgactcgg tcttaaagga ttctagtgaa aaattgcagg
     5581 acaataaata tgaccttggc cgattggtga atgttcggga tcgtgccctc aaaagtctcc
     5641 tagctggaaa atttataaaa gctagagata agaacattgt ctttaatgtc gaagttccag
     5701 aggagattca ggtagagggg gtgagtctac ttgattttct aaccgttgtg tctatccttt
     5761 gtgacaacgc tattgaagct agtgtagaag cctgtcaacc tcatgtttca attgcctttt
     5821 ttaaaaatgg agcacaggag acctttatca ttgaaaattc catcaaagaa gagggaatcg
     5881 atatttctga aatcttctcc tttggagcaa gttctaaagg ggaggagaga ggagttggtc
     5941 tctataccgt tatgaaaatt gtggaaagtc atcccaatac cagtctcaat accacctgcc
     6001 aagatcacgt ttttcgtcag gtacttactg taatacatat agaatgaaga aaaaataaga
     6061 ccgagagtgc gttctcttgg tcttgttttt ttatagttgt attggctgat aaaatccttt
     6121 tgtatttttt tgttcaatta tattaaatct atataagaaa tcttcccacc atcctccacc
     6181 tataatttgg ttgagttcgg tagttgttag ttcttgaaat gaagttaggt tttgtttctt
     6241 atccatgtta tgattctcct ttttgataag ataataaata gttatagagt gttatctgaa
     6301 aattaatcag aatgggttaa aattttatct ttgaaataat caaaatatgt tttctttgta
     6361 gttacactag tgacgcgacc ttgtaagcca tattggatga gtttactatc ctcgttagat
     6421 agttttgcaa gagcggttaa tttaaagaga ttgccttgct ctgttctggt aggagtttga
     6481 tcaatactct gaagttggcc gatgatggtg gtgccgtgat ttccaatctt ctccagtttt
     6541 aatcttacag tttgtccttt atctagtaag gggagatagt cagatgatac gtagtaagtg
     6601 attagtactt ctcttgtatc tgtgatgaca gggaatattt gagcaatttc tgtaccagtt
     6661 ggaattctat ttttaccttc aaattcgctg ttcagatgaa cgataccttt acttggagcg
     6721 gttaaggtat tattttctaa gcgctgtgtc gcttgatcta gttgtacttt taattctgtt
     6781 aattgattct ccacggttag ttgttgctgt gaggctgttt gtaaaaactg agtgcggagt
     6841 acttcaattt tggttgctaa actattatca taagttgcta cacttccgat accagcttgc
     6901 tgaattttga tgcttgcgat agatgattca agacttgcaa tactttgatt aatttgagat
     6961 aaaaatggct cctctgccgt tccttgtgtt tgtccttgag aggctataag ataacgattt
     7021 aaaattgact ggtgcggatt gccagttggt aagcgtgctc tgttatttat gatagcatct
     7081 ctcaactctt gatattctcc aatttgttgt tgaacttttg taatttcttg ttcgatggct
     7141 gatgaactgc tattggtaag attagcttga tttgaaactt cagtgttagt ctttgagata
     7201 cccagttcaa tatcatggga ttgtttagta aaattcataa aggtattatg gtagccaaac
     7261 tcatcctcgc tagaaaaaag atcagtcgct ttttctaagc tttgtttcaa gattccaagt
     7321 ccttcttttt gcttctcaag tctttgtaat tgagttgcta aggcagtttt ctgactttct
     7381 tccattgttt cagagtattt gatgagtaag tcacctttct caactacttg atttgccact
     7441 aaatgattag caaggatagg attatcactg gtcgactgaa tagatgcaat gacacttgta
     7501 ggggcgattt ctccttggga agtaacagta atttcttttg tggcaacaag ggagaaaatc
     7561 aagatgaaag taaatagtaa tgaaagaggt ataatgaaca ctgtcgcata gttatggtaa
     7621 cgtctctgat aaaactcgac acttctaaaa agattaggat tcatgacatt ctccttattt
     7681 attgaataga tgatggtaga agccttgcgc ctgcattaac tcttggtgac taccaacttc
     7741 aatgattttc ccctggtcaa gaacaatgac acggttagtt cgttcggcta tactgagacg
     7801 atgggctaca aagagaatgg ttttatcagt tagggatata agattatcta taaccttttt
     7861 ctcagtcaag acatcaagac cgctagtagc ttcatctagt attaaaacag gagctttagt
     7921 taaaagagca cgagcgagag cgattcgttg cttttgtcct cctgatagac cagctccatc
     7981 agagagctga gtttgatagc ccataggcat tctttcaatg tcttgacgga tttcagctaa
     8041 ttcacaagct cttagaatat cttcttggct aatcatatga ttaccgccca aggttaaatt
     8101 ttccaagata gagccattaa agatataggc ttgttggggt aggtaattaa tatgacggcg
     8161 caagactttt ttatcaatgt ttttaatatc ctgataattg atggaaatat gccctttgta
     8221 gggttcaaag aaattgacaa tcattttggc taaagttgtt ttaccagaac cactaactcc
     8281 aactaggcta accttatctc cttgtttaat cgtgagatta atatctgtta aggtatctcg
     8341 tccaaaacca tacttataag aaaggtcatc aaattcaata tcgcccatca aaaaatgtga
     8401 atgaacaggg ttttcttgaa cttgaaattc agattcgact agatagactt cgttcaaacg
     8461 gttattagcg accttcgcag attggagttt ggtttggagg ttgataatat tttccatagg
     8521 agttgtaaag taagaaaaaa gtgtgttaaa ggtaatcagc tgaccgatag aaattttact
     8581 cgacatgact aattgagcgc caaaccatag gataaggata ttcagaacta attttgttcc
     8641 ctgctttaaa ctcgtttgta aaatagaata tttactgagc ttaaaggatt tttccaaata
     8701 atctacaaat tcgctgtcta tattttgata gcgattttct tcactcgtga gcgactttat
     8761 agtttcaatc ccgttgatat cttcgataat ggcagagcta accatagaat tactttgcat
     8821 gacatcatgg ttcatttttt cgaaaggttt cataaaagaa aagatgatga acatgtatat
     8881 aggaatggaa agaagagaaa ggaggaagag attagggttt tgtgccagta agacgccccc
     8941 tacaagaatc agaatagaaa catccagaaa aagagaaaga atggtagaag ccaaggcatc
     9001 tataatagag ttagcatctg tgaaccgtga aatgatttct cctgtacgac gtgtcgcaaa
     9061 gaaagacatg ggaagttcaa aaatatggcg aatataggat aaaatcacat caatgcttaa
     9121 tctctggctc agaacggtta ggagataatc tctggaaaag ctcatgactt gttggaggat
     9181 ataggtgata accagaccaa ctgagatgat tcctaaagtt gatttcatct gatttgggat
     9241 gtattcatcc aagattcctt ggagataata agaaccaccg atattgataa tagtgaccaa
     9301 taagcttgag agaacaatgt aagcaatgag agatttttgt ttgaaaatca gaggaaggaa
     9361 gcttagtaga ccattctttt tatctttatg gggttgatag ctgggtttgg gagctagaaa
     9421 aatagctact ccagtccatt cagagaaaaa gcgttctttt gacattttag tgatttttac
     9481 agaagggtca ggatcaccaa taatcagata gtctttcttt gtttgataga caacatagta
     9541 atgttggagt tttccttctt tgttaacgtg aacgataaat ggatagggga catcactcat
     9601 gtcaaagaga gttttatctg cttgaacagg ccttgtttca aagcccattt catcagcggc
     9661 ttttacaatg ccaagagcag tcgtcccttc tttattggtc tttgcaagtt ctctcaagtg
     9721 agctagagaa aaatctgaac catagaattt agcaatcgag gctaaggcag caacaccgca
     9781 gtctctagca tctatttgag gaacaaatgt acgtttataa gaagtcattg gcaattcctt
     9841 tcatatagtg gatagctcta ttatgacata aaaacaattt cgtgctttat aaaatcttga
     9901 atagtcattg aaatttcctg aatggtaaaa aagtgattag aaattatctt ttaaaaaaaa
     9961 tttagaggta gttttaaata aaaaagctaa tttaagacgt ttcgatgaca attcaagatt
    10021 tggatgaaaa actttaacaa atagtgctat actaaacttg tcaaagttgc aacaagacaa
    10081 aaattaaaaa taaaaaagga gtatttgtta tgaatacaaa aatgatggaa caatttcatg
    10141 aaatggatat agctatgtta tctagtattg aaggaggcaa gaataattgg caaactaatg
    10201 ttttcgaagg tggtagtgct gcttttggtg gctgggggtt agggacagct atttgtgctg
    10261 cgagtggtgt tggagcgcca tttatgggag catgtggata cataggagct aaatttggtg
    10321 tggctctttg ggcaggagta acaggggcaa cgggtggatt ttaacaaaag gagacttgta
    10381 tgaatactta ttgtaatata aatgaaacaa tgctgagtga ggtttacgga ggtaattccg
    10441 gaggagcagc tgtagttgct gctttaggtt gtgcagcggg tggagtgaaa tatgggaaaa
    10501 ttctaggacc atggggcgct gcaataggag gaattggagg agcagtggtt tgtggatatt
    10561 tagcctatac cgctacatca taaaaatgaa agctaaattt tatgaaggct atattcttta
    10621 ttattctctt cgcttttcaa acctatctta tttatctatc cataagtatc tctgataaaa
    10681 aacaaaagac tattgaatta acatcattga attgttttgt catattattt ctaatctatg
    10741 ataaattaat ttttctcttt attgcctatg tttttttgat aatttttata ttaaacttgt
    10801 tccgtaactg aaaagtgaca tactatatga atacaaaaat gatgtcacaa ttttctgtta
    10861 tggataatga aatgcttgct tgcgttgaag gtggagatat tgattgggga agaaaaatta
    10921 gttgtgcagc aggggttgca tatggcgcaa ttgatgggtg tgcaacaacg gtttgacatt
    10981 tctattggga ccatttgcta taggaatagg tgtaactggt gctgcaggtg gagctatact
    11041 tggaggtgta gcctatgcag caacatgttg gtggtaatta tggattttaa aagttttatt
    11101 attggtttag tagttggtat atttggtcct tatatggatg acttaattag aaaaatattt
    11161 tcaaaatctt ccaaaaagga tacggatagt actctctaaa aaataaattt ctcccctgta
    11221 tttgctagct taatttacag gggagtttct ttaatattgt ttcgcctgtc aaaatgatat
    11281 gtgatagcag gatgaaaagt ctacaaacaa gttggtatca atacaatata aagaggaaag
    11341 tatgtttttc atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta
    11401 tgatttgagt gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc
    11461 aactaagata aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt
    11521 tcgttctgta tctgatcatg tccatctttc tttatccgct tagggagagt atttggtata
    11581 atctatttta taccatagcc tatatgattg cggttatgat ctatttttct ttaattaaaa
    11641 agaaagaaaa gaaatgaaag attttcttga ttaaaaagaa tcatattctt tgtgagattg
    11701 ttcctgggtc agttgccttt gcttgtttct acttatctat ttctatttcg tcagttttcc
    11761 aatttctttt agtggttatt aacttagctt ctattttggt cactgtttac ctcactaggg
    11821 aaatgcggat aaaagagttt gaagatgatg atttggttag tcctagaacc aatcaactta
    11881 tgttcatcgg cttgacaggc tttatgtcta ttatttgttt gtatagaggg atcacagcag
    11941 gagaatccta ccaacaaata atcgcttata ttggcgctat tctctgcttg accatcatgc
    12001 ttctgctcat ttggggattg aagtattata aaaagtagag gctaatgcag tttttgcaat
    12061 ttaagatgtc ttgatgacaa ttcaagattt ggatgaaaaa ctttgacaaa tagtgctata
    12121 ctgaaattgt caaagttgca acgggtgctg ctacattatg ttaaaaatcg ctcttgattg
    12181 ataagttgga tttgttagga aaggagtaaa taattatgga taagaaaaag atagtttcga
    12241 ctataatatg tatagtattt cttgtagtgt cagtagataa tttttttaga gacttaaccc
    12301 cgttactgtt cattttaaat attattggcc tgtcttgctt ttcagtgcta acatacatta
    12361 acataaaaga gatactctta aatataagta aatgatgatt tggttagtcc tagaaccaat
    12421 caacttatgt ttatcggctt ggcagatttt atgtttgtca tttgtttgta tagaggtatt
    12481 tcagaaacag aattctatca acaactaatc gcttatatag gtgtattctc tgcttgttta
    12541 tcacgcttct gctcatgtgg ggcttgaagt attataaaaa gtagctttct atccttttct
    12601 gacaggatat ttgagtagaa ggctctatta aattgttagt gaaataaatg aatggaggta
    12661 tttaatatga aatacagatt attttttgtt attttcttga gtagtgtgtt ggatattctt
    12721 ttagggacat ttttacaaat ctctatcgta tctattgggt ggcttgttct ttacagtggt
    12781 ttgtttgaag caggagtttt ccttcttgct aataaagggg tggcggtaaa aatcaaggaa
    12841 gtagatattc gaaatcgctt taaatttatt tttggaaaaa ccttatggtt tcaaattctt
    12901 ttgctcatct ttttgataat caaactttat cttggtttgg atgcgaggtt gattttattc
    12961 tatggacata ttttcattgt ctttaatgcc ttaatgtatc tattatctag tagtcaggtt
    13021 agccttaaaa aaaacaaact gtcttcttaa tcttacagca gtagagcctg acaaggtgag
    13081 gtcatagtag ggaggatttc tatgaaaaag tatcaacttc tattcaaaat aagtgcagtt
    13141 ttctcttact tatttttcgt atttggtctt tctcagatga cgcttattat tcaaaattat
    13201 tggcaatttt cttcccagat tggcaatttc gtctggattc aaaatttctt gagtttgcta
    13261 tttagcggag tcatgatttg gattctggtt aagacaggtc atggttatct ctttcacatt
    13321 ccaagaaaaa aatggctttg gtattcgatt ttgacagtat tagtggtagt gctccagatc
    13381 tcttttaacg ttcagacagc taaacatgtt cagtcaactg ctgaaggttg ggctgtattg
    13441 atcggttata gtgggaccaa ctttgctgag ctaggtatct atataacttt gttctttctg
    13501 actccactta tggaagagct aatctataga ggattactgc aacacgcctt ttttaagcat
    13561 tcgagatttg gccttgattt gcttcttccg tcaattttat ttgctcttcc tcatttttca
    13621 agcctgccta gtttgttaga tatcttcatc tttgcaacat ctggcatcat ctttgctagt
    13681 ttgacccgct ataccaagag catttatcct tcctatgcgg tgcatgtgat caataatatt
    13741 ttcgcaacat taccattttt gctgactttt ttacataggg tcttggggta aaaaaacaaa
    13801 aggcttgctt ttcagccata gaggagatta tcatgtataa acacttattt ttcctagatt
    13861 ccaaaacttt agatcggttg acaccctata ttctagtctt ggcttctgac accattgctt
    13921 ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt taatttccta aattccatgc
    13981 tagctttaat ggctatattc ataggggctg gctatgtggt cggattttgg ttactaatac
    14041 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa
    14101 ggcgacgttg acgtggtttg aatttgattt tcgaagagta taaaatggtt tgttttggaa
    14161 aggctagaac taaagaatga cgcgtaggaa gtctgtttgg tgaggaggat agttttatgg
    14221 agttttttga taaatttcat gccttgtgtt ttggattttt agtactaata attgtcatta
    14281 cagttcctta tacgattaac catggggttt tttttcaaaa tgaatctgca ttgattcttg
    14341 taagtcttct tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa atgatttctt
    14401 ttgggatgtt aagcaagaaa caacttttgc ttttcattgc aatctttctt ctaagtgtac
    14461 ttgagacgct ggtttatatt catttcttcg ctgtttcttc tggctcaggg gtccaacact
    14521 tggcggaagt cagcagagga atttccctgt ctttgatttt gactacctca gtttttggcc
    14581 ccatccagga ggaactcatt ttcagaggac ttcttcaagg tgcggttttt gacaattctt
    14641 ggttagggct tgtgctaact tcctctctct tttctttcat gcatggacct tctaatgtcc
    14701 cttcgtttat tttttatcta cttgggggtt tgttgctggg ctttgcttat aaaaagagtc
    14761 aaaacctatg ggtttctact ctagtccaca tgttttacaa cagttggcca ctcctatatt
    14821 atttataaaa attatgaaaa ggtaagcaga agatggtgct tacctttttc aagctataat
    14881 gatacccaag ccaatccaga ggcttttctt tgagaatcgg gttagagtgg ttgacgaata
    14941 ggccaaaaac tagtagaata gtaaggaaac tttatacgga ggaaagaaat ggatttgggt
    15001 gataatgagc taacactgac tcccatacct gggaaaagtg gcaaggctta tatgggtagc
    15061 tatcctgacg ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct acctggtcta
    15121 gctagagaac aaattgctcc acaattatta tggagtcgtc gtttggcaga tgggcgtgat
    15181 atgtgtgctc aagaatggtt gacaggcaag atattgaccc cctatgatat gaatcgtaag
    15241 caaatcgtca atattttaac ccgtcttcat cgctcacgtc cgttgatgac acaattgagt
    15301 cgtttgggct atgccatgga aacacctgta gatttactac agtcttggca ggaaacggct
    15361 ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga tggctgattt acgtcagact
    15421 attccaggat ttagagagga ccatgcgacc attgtccatg gagatgtacg acatagtaat
    15481 tggattgaga cagatagtgg cttgatttat ttagtagatt gggattcggt tcgcttgacc
    15541 gatcgcatgt ttgatgtggc ccatatgctc tgccattata tttcagaaca tcagtggaag
    15601 gaatggttga cctactacgg ttacaagtac aatcaaacgg tattaagtaa attgtattgg
    15661 tatggtcaat tgtcttattt gagtcagatt tccaagtatt atatgaacca agatttagaa
    15721 aatgtcaatc gggagattca tggtttgcgt catttccgag acaagtatgg aaagagaaga
    15781 tgagagttag aaatcgtaaa ggggcaacag aattactaga ggcaaatccc cagtatgtgg
    15841 tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt gtttggcaat gataatccca
    15901 ttcatgtgga agttggaagt ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc
    15961 ctgacatcaa ctatatcggg attgatattc aaaagtctgt tttgagctac gctttggaca
    16021 aggtgcttga agttggagtg cctaacatca agctcttgtg ggtagatggt tctgacttaa
    16081 ctgactactt tgaagacggt gagattgatc gcttgtatct gaacttttca gatccatggc
    16141 cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac cttcttggat accttcaaac
    16201 gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga taaccgtggc ttgtttgagt
    16261 acagtttagt gagcttttct caatatggca tgaaactcaa tggtgtctgg ttagatttgc
    16321 atgccagtga ttttgaaggc aatgtcatga cagaatacga gcaaaaattc tcaaacaagg
    16381 ggcaagttat ctaccgagtt gaggcagaat tttaagagat agcctaaaat taggctgtac
    16441 aagtgctttt gctttacata agttggcaaa cgtgctatac tgatagtaag aatatgaaaa
    16501 gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat
    16561 cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa gctccttttg aactcgtgga
    16621 tatcgagtat ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacccga
    16681 aggaattacc ttgaacgaca cggcagactt gacagaaatg atcagtcctg tcctagacac
    16741 catcaagcca gatcccttcc cagaacaata tttcctagaa attaccagtc caggtttgga
    16801 acgtcctttg aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca tccatgtcgg
    16861 gctctaccaa gccatcgata agcaaaaggt ctttgaagga accttgttgg ccttcgaaga
    16921 ggacgagttg actatggaat atatggacaa gacgcgtaag aaaaccgtcc aaattccata
    16981 cagtttagta tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt
    17041 gaggattcaa aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg
    17101 aagaagacaa gggaatcaaa aaagaagata tcatcgacgc agtagtagag tcgcttcgtt
    17161 ccgcttatcg cagacgctat ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa
    17221 caggtgactt tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt
    17281 tggaaatcag cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa
    17341 tcaagtttga agaagcacca gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa
    17401 ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac
    17461 atgagcaaga aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca
    17521 accttggtag catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg
    17581 cttctcatga tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga
    17641 acgtctttgt tagccgtagc catccagaaa tgatcaaacg tttgatggag caagaaattc
    17701 cagaagttta tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta
    17761 cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac
    17821 gtggtggtgc taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta
    17881 aaaatgaccg catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc
    17941 cagctgaatt tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg
    18001 aaaacgacag caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg
    18061 gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca
    18121 agtctgctag cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa
    18181 acgatactgt agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc
    18241 ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg
    18301 tcaagaacaa ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg
    18361 cttatatcaa actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc
    18421 gcagttttag catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc
    18481 acaaagtgaa aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg
    18541 cttgctcagc gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa
    18601 gacggcaagg ccaagttggt ctttctagct catgatgctg gacccaatct gaccaagaag
    18661 attcaagata aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa
    18721 ttaagcatag cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca
    18781 aagaaaatga ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt
    18841 gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga
    18901 gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat
    18961 tgctgccagc tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa
    19021 agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga
    19081 agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa aaagtagcag cgaaaccgca
    19141 aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa
    19201 gcaaaataag ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg
    19261 ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc
    19321 taagaagcag caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggacaaacg
    19381 ttcaaatcaa gtggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga
    19441 gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa
    19501 agaagccttg gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc
    19561 taagttagct gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa
    19621 agaacctgca gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga
    19681 ttatgatcat gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca
    19741 agtgagaaat caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa
    19801 caagaacaac cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc
    19861 aacagaattt gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg
    19921 tgaaccagct gaaatcgtta agaaactttt catgatgggt gtcatggcca cacaaaacca
    19981 atccttggat ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca
    20041 aaaggttgaa gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa
    20101 tgaagatgaa ttggttgagc gtccaccagt tgttactatc atgggacacg ttgaccacgg
    20161 taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg
    20221 tattactcag catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct
    20281 tgatacacca ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga
    20341 tattacgatc ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat
    20401 caaccactca aaagcagcta acgttccaat catcgtagcc attaacaaga ttgataaacc
    20461 aggtgctaac ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc
    20521 ttggggtgga gattctgaat ttgttgaaat ctcagctaaa ttcaaccaaa atatcgaaga
    20581 attgttggaa acagtccttc ttgtagctga aatccaagaa ctcaaggcag acccaacagt
    20641 gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac
    20701 ccttcttgta caacaaggta ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt
    20761 cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc
    20821 aacaccagtc tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt
    20881 ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat
    20941 gaaacaacgt caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc
    21001 tggggaactc aaatctgtta atgttatcat caaggctgat gtacaaggtt ctgttgaagc
    21061 cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc
    21121 agcggtcggt gctatcaacg aatcagacgt gacccttgcc gaagcttcaa atgcctttat
    21181 cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt
    21241 ggaaatccgt cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa
    21301 agggatgctt gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac
    21361 cttcaaggtg tctaaagtgg gaactatcgg tggatttatg gttatcaacg gtaaggttgc
    21421 ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc
    21481 aagcttgaaa cactataaag acgacgttaa ggaagttaca aacggccgtg aaggtggatt
    21541 gatgatcgac tgctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga
    21601 agaaatcaag agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc
    21661 gatggtttca ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga
    21721 taaatcagtt ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc
    21781 gtttcaattt aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt
    21841 tggttcaaag tagagaaagg aatatcatgg caaatcattt ccgtacagat cgtgtgggca
    21901 tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc
    21961 aaggtgtgac catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt
    22021 acaccatttt gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag
    22081 caactggtac catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt
    22141 tgaccttcgt caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca
    22201 atctggataa gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt
    22261 gaatttgaaa tggaaaaata ttctttta
//
LOCUS       DAVBOH010000032        22095 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOH010000032 DAVBOH010000000
VERSION     DAVBOH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.032"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..245)
                     /locus_tag="VQ873_001412"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQ873_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ873_001413"
     CDS             complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ873_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3107663.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2701..3570)
                     /locus_tag="VQ873_001414"
     CDS             complement(2701..3570)
                     /locus_tag="VQ873_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3107664.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3793..4473)
                     /locus_tag="VQ873_001415"
     CDS             complement(3793..4473)
                     /locus_tag="VQ873_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3107665.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4431..5537)
                     /locus_tag="VQ873_001416"
     CDS             complement(4431..5537)
                     /locus_tag="VQ873_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3107666.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5648..5902)
                     /locus_tag="VQ873_001417"
     CDS             complement(5648..5902)
                     /locus_tag="VQ873_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107667.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6260..6793)
                     /locus_tag="VQ873_001418"
     CDS             complement(6260..6793)
                     /locus_tag="VQ873_001418"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3107668.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6780..6995)
                     /locus_tag="VQ873_001419"
     CDS             complement(6780..6995)
                     /locus_tag="VQ873_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107669.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6962..7105)
                     /locus_tag="VQ873_001420"
     CDS             complement(6962..7105)
                     /locus_tag="VQ873_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3107670.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7339..9057
                     /locus_tag="VQ873_001421"
     CDS             7339..9057
                     /locus_tag="VQ873_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3107671.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9168..9515
                     /locus_tag="VQ873_001422"
     CDS             9168..9515
                     /locus_tag="VQ873_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3107672.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9793..10629)
                     /locus_tag="VQ873_001423"
     CDS             complement(9793..10629)
                     /locus_tag="VQ873_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107673.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10642..11271)
                     /locus_tag="VQ873_001424"
     CDS             complement(10642..11271)
                     /locus_tag="VQ873_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3107674.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11281..11922)
                     /locus_tag="VQ873_001425"
     CDS             complement(11281..11922)
                     /locus_tag="VQ873_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3107675.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12068..13297)
                     /locus_tag="VQ873_001426"
     CDS             complement(12068..13297)
                     /locus_tag="VQ873_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3107676.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13287..14453)
                     /locus_tag="VQ873_001427"
     CDS             complement(13287..14453)
                     /locus_tag="VQ873_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3107677.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14597..15610
                     /locus_tag="VQ873_001428"
     CDS             14597..15610
                     /locus_tag="VQ873_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3107678.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15655..16074)
                     /locus_tag="VQ873_001429"
     CDS             complement(15655..16074)
                     /locus_tag="VQ873_001429"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3107679.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ873_001430"
     CDS             complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ873_001430"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3107680.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17577..18455)
                     /locus_tag="VQ873_001431"
     CDS             complement(17577..18455)
                     /locus_tag="VQ873_001431"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3107681.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18471..19976)
                     /locus_tag="VQ873_001432"
     CDS             complement(18471..19976)
                     /locus_tag="VQ873_001432"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3107682.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19991..20527)
                     /locus_tag="VQ873_001433"
     CDS             complement(19991..20527)
                     /locus_tag="VQ873_001433"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3107683.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ873_001434"
     CDS             complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ873_001434"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3107684.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ873_001435"
     CDS             complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ873_001435"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3107685.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21786..21986)
                     /locus_tag="VQ873_001436"
     CDS             complement(21786..21986)
                     /locus_tag="VQ873_001436"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3107686.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6570 a         4739 c         4033 g         6753 t
ORIGIN      
        1 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
       61 tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagctctata
      121 atctcttaat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
      181 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt tgatttcttc tttagttgat
      241 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
      301 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
      361 tctacaacct aaaaacagtg ttttgaacag tctgcagcta actttctata acaaaatgaa
      421 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
      481 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
      541 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctaacttaaa
      601 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
      661 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
      721 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
      781 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
      841 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
      901 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
      961 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
     1021 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
     1081 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
     1141 taccacgtcc agtaattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
     1201 cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata acgatgtctt
     1261 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
     1321 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
     1381 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
     1441 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
     1501 ctacaaggat agctccgtcc atttgagcag caccagtgat catattttta acgtagtccg
     1561 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
     1621 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
     1681 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
     1741 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
     1801 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
     1861 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
     1921 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
     1981 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
     2041 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
     2101 caggacaatc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttt
     2161 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
     2221 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
     2281 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
     2341 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
     2401 agggaggact attccaactt caacccacta ttaatatata atagaatgaa aactgcacaa
     2461 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     2521 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     2581 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     2641 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     2701 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     2761 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     2821 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcgggtcc
     2881 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     2941 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     3001 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     3061 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     3121 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     3181 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     3241 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     3301 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     3361 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     3421 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     3481 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     3541 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     3601 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     3661 aaaataggat tcatagtttc ctagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     3721 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga
     3781 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     3841 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     3901 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     3961 ttcagttttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     4021 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     4081 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     4141 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4201 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4261 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4321 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4381 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4441 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4501 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4561 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4621 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4681 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4741 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4801 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4861 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4921 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4981 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctaagattag ttctgccaat
     5041 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     5101 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     5161 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5221 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5281 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5341 cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5401 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5461 acccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa aagtttggcg
     5521 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5581 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5641 attatcctta acatgatagg taattttcac ctggtataag agtcttcagt agtttatata
     5701 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5761 tatctttatc aacctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc
     5821 tcactgtgaa agttttcttc cagtctgaac cacttttatt aggcttagat atgctcatga
     5881 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5941 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     6001 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     6061 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     6121 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6181 attgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6241 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6301 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6361 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6421 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6481 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6541 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6601 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6661 gtgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6721 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctggc tcttgttcct
     6781 taaagctcgt catctttttt taaagtgacc ttaatatact ttaaagctgc ccatacggag
     6841 ggcagagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6901 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6961 tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg acgccaacac
     7021 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatggaatct aatgctcgct
     7081 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagca
     7141 actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg aatttttcct
     7201 aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     7261 cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa
     7321 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7381 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7441 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7501 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7561 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7621 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7681 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7741 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7801 gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat
     7861 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7921 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7981 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     8041 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     8101 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     8161 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     8221 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     8281 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     8341 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8401 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8461 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8521 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8581 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8641 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8701 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8761 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8821 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8881 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8941 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     9001 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     9061 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     9121 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     9181 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     9241 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttt
     9301 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9361 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9421 taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9481 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9541 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9601 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
     9661 aacaatgttt tagaaatcac agtgggctat tccatattca attatccaga ttcaatcgct
     9721 attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg cagtttcagc
     9781 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
     9841 tttttgactg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
     9901 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
     9961 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aataatttgc
    10021 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
    10081 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
    10141 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
    10201 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
    10261 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
    10321 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
    10381 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
    10441 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
    10501 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
    10561 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
    10621 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
    10681 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
    10741 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
    10801 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
    10861 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
    10921 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
    10981 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
    11041 tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat tataaaagat
    11101 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
    11161 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaatcaga
    11221 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tagctgcccc
    11281 ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca caatcccaat
    11341 taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat cgcggttagc
    11401 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
    11461 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
    11521 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cagcctcata
    11581 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
    11641 gttgagaaca aaggcaataa tagctgcagg aaggcgatct aaacgaatcc caatacttgg
    11701 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
    11761 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
    11821 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
    11881 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
    11941 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
    12001 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
    12061 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
    12121 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
    12181 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct tgataatgct
    12241 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
    12301 aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca
    12361 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
    12421 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
    12481 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
    12541 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
    12601 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
    12661 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
    12721 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
    12781 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
    12841 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
    12901 tcaagagaga atcctctgag taggtcaggg cctccaataa tttctcacgt gccacatctg
    12961 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
    13021 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
    13081 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
    13141 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat
    13201 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
    13261 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
    13321 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
    13381 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
    13441 aacaaaacaa agagaacatt aataggatgg atgtttaatt gacttcccaa aatcaatgga
    13501 gagacaaaac ggccttcaat agtttgttct acaataaaga caatcactac tttcaaaagc
    13561 atgactggac cagcaatcaa acccaatact agggcaggaa gcatggctag aaagctacca
    13621 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
    13681 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
    13741 cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc aacaggttcc
    13801 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
    13861 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta
    13921 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
    13981 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
    14041 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
    14101 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
    14161 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
    14221 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
    14281 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
    14341 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
    14401 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
    14461 tcctttctat tgtcctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
    14521 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
    14581 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
    14641 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
    14701 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
    14761 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
    14821 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
    14881 tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
    14941 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
    15001 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
    15061 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
    15121 ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc ataaccacta
    15181 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
    15241 cgttggcgaa tttgtacgta tgcaggttat ttcaacttta ccagaagctt acgaaggctt
    15301 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
    15361 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
    15421 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacaccca accaaaaatt
    15481 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
    15541 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
    15601 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
    15661 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
    15721 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
    15781 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
    15841 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
    15901 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
    15961 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
    16021 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccataggtca
    16081 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
    16141 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
    16201 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
    16261 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
    16321 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
    16381 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
    16441 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
    16501 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
    16561 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
    16621 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
    16681 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
    16741 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
    16801 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
    16861 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
    16921 cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct tgggcaatgt
    16981 tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg aaaagtccaa
    17041 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
    17101 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
    17161 ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg ttgaagacac
    17221 gtcccaaagt ttctttacct actggtacag agattggacg acccgtgtcc aatacttcca
    17281 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
    17341 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
    17401 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
    17461 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
    17521 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
    17581 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
    17641 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
    17701 tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
    17761 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
    17821 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
    17881 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
    17941 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
    18001 acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg
    18061 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
    18121 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
    18181 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
    18241 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
    18301 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
    18361 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
    18421 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
    18481 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
    18541 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggtatggaac
    18601 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
    18661 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
    18721 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
    18781 ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
    18841 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
    18901 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
    18961 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
    19021 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
    19081 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
    19141 cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag atcatcgtat
    19201 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagtataa
    19261 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
    19321 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
    19381 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
    19441 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
    19501 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
    19561 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
    19621 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    19681 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    19741 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    19801 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc atgagcacgc
    19861 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    19921 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    19981 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    20041 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    20101 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    20161 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    20221 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    20281 aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa
    20341 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    20401 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    20461 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    20521 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    20581 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    20641 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    20701 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    20761 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    20821 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    20881 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    20941 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    21001 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    21061 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    21121 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    21181 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    21241 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    21301 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    21361 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    21421 gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat
    21481 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    21541 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    21601 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    21661 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    21721 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    21781 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    21841 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    21901 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    21961 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    22021 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    22081 aaattatttc cattt
//
LOCUS       DAVBOH010000033        21565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOH010000033 DAVBOH010000000
VERSION     DAVBOH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.033"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ873_001437"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ873_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ873_001438"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ873_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3107687.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ873_001439"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ873_001439"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3107688.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ873_001440"
     CDS             complement(5187..5750)
                     /locus_tag="VQ873_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3107689.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ873_001441"
     CDS             complement(5835..6389)
                     /locus_tag="VQ873_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3107690.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ873_001442"
     CDS             complement(6400..7623)
                     /locus_tag="VQ873_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3107691.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ873_001443"
     CDS             complement(7660..10110)
                     /locus_tag="VQ873_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3107692.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ873_001444"
     CDS             complement(10310..11239)
                     /locus_tag="VQ873_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3107693.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ873_001445"
     CDS             11379..11666
                     /locus_tag="VQ873_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3107694.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ873_001446"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ873_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3107695.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ873_001447"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ873_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3107696.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ873_001448"
     CDS             complement(13807..16353)
                     /locus_tag="VQ873_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3107697.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ873_001449"
     CDS             complement(16476..16916)
                     /locus_tag="VQ873_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3107698.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ873_001450"
     CDS             complement(16891..17760)
                     /locus_tag="VQ873_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3107699.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ873_001451"
     CDS             complement(17738..18238)
                     /locus_tag="VQ873_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3107700.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ873_001452"
     CDS             complement(18249..18947)
                     /locus_tag="VQ873_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3107701.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ873_001453"
     CDS             complement(18940..19176)
                     /locus_tag="VQ873_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3107702.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ873_001454"
     CDS             complement(19276..20202)
                     /locus_tag="VQ873_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3107703.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ873_001455"
     CDS             complement(20277..21092)
                     /locus_tag="VQ873_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107704.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ873_001456"
     CDS             complement(21096..21416)
                     /locus_tag="VQ873_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3107705.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6504 a         4720 c         3807 g         6534 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga atatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt tttccccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggtt
//
LOCUS       DAVBOH010000034        20943 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOH010000034 DAVBOH010000000
VERSION     DAVBOH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.034"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..183
                     /locus_tag="VQ873_001457"
     CDS             <1..183
                     /locus_tag="VQ873_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107706.1"
                     /translation="IEFKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRY
                     KEGKLLFVKKEASDVL"
     gene            173..661
                     /locus_tag="VQ873_001458"
     CDS             173..661
                     /locus_tag="VQ873_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107707.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            661..2538
                     /locus_tag="VQ873_001459"
     CDS             661..2538
                     /locus_tag="VQ873_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3107708.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            2559..2801
                     /locus_tag="VQ873_001460"
     CDS             2559..2801
                     /locus_tag="VQ873_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107709.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2818..3672
                     /locus_tag="VQ873_001461"
     CDS             2818..3672
                     /locus_tag="VQ873_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3107710.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            3726..4085
                     /locus_tag="VQ873_001462"
     CDS             3726..4085
                     /locus_tag="VQ873_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3107711.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            4036..6393
                     /locus_tag="VQ873_001463"
     CDS             4036..6393
                     /locus_tag="VQ873_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3107712.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            6405..9218
                     /locus_tag="VQ873_001464"
     CDS             6405..9218
                     /locus_tag="VQ873_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3107713.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(9249..9437)
                     /locus_tag="VQ873_001465"
     CDS             complement(9249..9437)
                     /locus_tag="VQ873_001465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107714.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            9456..10022
                     /locus_tag="VQ873_001466"
     CDS             9456..10022
                     /locus_tag="VQ873_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107715.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            10174..10584
                     /locus_tag="VQ873_001467"
     CDS             10174..10584
                     /locus_tag="VQ873_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3107716.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            10632..16862
                     /locus_tag="VQ873_001468"
     CDS             10632..16862
                     /locus_tag="VQ873_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3107717.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            16937..17221
                     /locus_tag="VQ873_001469"
     CDS             16937..17221
                     /locus_tag="VQ873_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107718.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            17235..17531
                     /locus_tag="VQ873_001470"
     CDS             17235..17531
                     /locus_tag="VQ873_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107719.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(17545..17742)
                     /locus_tag="VQ873_001471"
     CDS             complement(17545..17742)
                     /locus_tag="VQ873_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107720.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            17902..18543
                     /locus_tag="VQ873_001472"
     CDS             17902..18543
                     /locus_tag="VQ873_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3107721.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            18553..19638
                     /locus_tag="VQ873_001473"
     CDS             18553..19638
                     /locus_tag="VQ873_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3107722.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            19689..19922
                     /locus_tag="VQ873_001474"
     CDS             19689..19922
                     /locus_tag="VQ873_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107723.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            19919..20302
                     /locus_tag="VQ873_001475"
     CDS             19919..20302
                     /locus_tag="VQ873_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3107724.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            20340..20612
                     /locus_tag="VQ873_001476"
     CDS             20340..20612
                     /locus_tag="VQ873_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107725.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            20682..>20943
                     /locus_tag="VQ873_001477"
     CDS             20682..>20943
                     /locus_tag="VQ873_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107726.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGA"
BASE COUNT         7184 a         3318 c         4303 g         6138 t
ORIGIN      
        1 attgaattta aacgtgttgg tatcgttgat gggaaggcag tagaagtcac tcttcgagaa
       61 ccttattcga gagatctact gaaggttgtc aagtcgatta agcaacgtca gaaattgata
      121 gcttatcgtt ataaagaagg aaagctgcta tttgtgaaga aggaggcatc agatgtcctc
      181 tgaacaacag gaacgaatgg cagttcaata tgcagagcgt agtcttttat ttactgtaaa
      241 aagtctttta aagattctag aatggtctag acgtcaggct ttagcacagg attccgccta
      301 taagatagga gtgcagaaat tagaagaatt gctacaatct ccctatgcga ttgatacgat
      361 taatctgaaa aaagattttt tagacaaacc aattgatata gagaaattta aagctttttt
      421 agaaaaagaa gagattcctt tagccatcgc ttggcaaggg gattctctac atttctacgc
      481 gaaagaccgt tcgattttag acaatcattt agaccatctt ttagaaaaaa tggttaatga
      541 tccggagaaa ttagctgatt ttaccatgga taagtcatta gatgatgcta ttgatgaagc
      601 taaatcccaa attaccttta gacaagaagg agccgtcaaa cagaaagaga tggtgagatg
      661 atgtacagtg gaaaaaaatt cctactattc tcactgttag gtatcttact aggctatctt
      721 tttcatcgtt tgacgctttt gtatgattcc tatactggaa ataccttaga taaatggact
      781 catcttctga tggaaggtca agatgaagtt cttcagtcgc catggaatgt ttcttttact
      841 ggaaaatcaa gtgctttttt tctactaggt tttgtgatga tgttactggt ttatctctat
      901 ctagagactg gtaaaaaaca ataccgagaa ggggtagaat acgggagcgc ccgttttgga
      961 actctaaaag aaaagaagct cttttacggt aaggaatttt ctcatgatac gatcttagca
     1021 caagatgttc gtttgacatt attagataaa aaaccacccc aatatgatag aaataagaat
     1081 attgcggtga ttggaggttc aggaagtggg aagacatttc gctttgtgaa acccaatctg
     1141 attcagatga atagttctaa tattgtagtg gatcctaaag atcacttggc cgagaaaaca
     1201 ggcaaactct ttttagaaca tggctaccaa gtaaaggtgt tagatttagt caatatgaag
     1261 aactcagatg gctttaatcc ttttcgctat atagaaacag aaaacgattt gaatcgcatg
     1321 ctgactgttt attttaataa caccaaaggc tctggctccc gaagtgatcc attttgggat
     1381 gaagcttcta tgactttggt tcgagcttta gcctcttact tagtcgattt ctataatcca
     1441 cctaaaacaa gagaacagct catagaagaa agtcgtttaa gtcaaaagga atatcaaaac
     1501 ttgttgaaac gtcaaaaaaa agaagtggaa gagcgaaaaa aacgaggtcg ttatccaagt
     1561 tttgctgaaa tctcaaaact cattaaacac ttatctaagg gtgaaaacca ggaaaaaagt
     1621 gtcttagaaa ttctatttga aaattatgct aaaaagtatg ggactgaaaa ttttaccatg
     1681 cgaaattggg cagattttca aaattataag gataagactc tggattctgt tatagctgta
     1741 accactgcta aatttgccct cttcaatatt caaagtgtca tggacttgac caaaagagat
     1801 acccttgata tgaagacatg gggcaaggaa aaatcaatgg tttacttagt tatcccagat
     1861 aacgatagta cctttcgctt tctttcagcc ctcttttttt caaccgtatt tcaaacccta
     1921 acaagacaag cagatattga ttttaagggt caattgcctc ttcatgtgag agtttactta
     1981 gatgagttcg caaatatcgg agaaattcca gattttgctg aacaaacctc aacagtccgt
     2041 tctcgaaata tgagtctcgt tcctattctt caaaatattg cccaacttca agggctctat
     2101 aaagaaaaag aagcttggaa aaccattttg gggaactgtg atagcttagt ctacttaggt
     2161 ggtaatgatg aagatacctt taaatttatg agtggcttac tcggtaaaca aaccattgat
     2221 gttcgaaata ctagtcgttc ctttggccaa acaggttcag gatccctttc tcatcaaaag
     2281 attgctcgtg acttaatgac acccgatgag gtcggaaata tgaaacggca tgaatgcttg
     2341 gttcgaattg ccaatatgcc tgtctttaaa agcaaaaaat acaattccac taagcatcca
     2401 aactggaagt acctagctaa tcaagaaagc gatgaacggt ggtggaacta tcaaatcaat
     2461 cctttgaatc aaagacaaga aaattatctt gacgacctta gaattcgtga tttaactttt
     2521 gaatctagtt taaaataaaa atagaaaaga ggaaatagat gattacgcat tttaaaggtt
     2581 ttgtttatgg agtagacgca agtgctatgt ttgcacaagc tatgtctttg ttacagaagg
     2641 gattgattgc agttggtgcc tttctcgttg ttgtggggat tgtcaacctt gcaaccaaca
     2701 ttaaagatgg tggaccaggt gttcggaatg ccattcttga aattgtcggt ggtgttatgg
     2761 taggggctgc tggagccttt gtaacccaga tttcaattta ggaggataaa caatgacatg
     2821 aatcttagtt tagtctcacc ctttgtttac cttgcatctg aaaaaatatc agctgaaaat
     2881 ttatttgaag gatttaatgt ggatttacaa tctacggtag atctgattaa atccctatct
     2941 agctacaatc caacagtttg gacttatatg tctagtatta ctaaaagtgt catgcagcct
     3001 cttggagttg cgattttatc agttgttctc atcttagaat tttcgaagat ggcaaagaag
     3061 attgctaact ctggtggagc gatgaccttt gaagcattag cgccgatgtt gattagttat
     3121 attatggtcg cagtggtcat taccaatact accgttatag tagaagctat catcgggatt
     3181 gcgagtcacg ccatcgaaca agtggcctcg attgtggctc acggtggggc gaagtatgat
     3241 acactctctg gattaaaagg ttcaggattt attggccgga tgattgtggg ctttttcgct
     3301 ctccttatct ggcttgttcg gatagtaagt gcagccatgg ttaatctttt ggtatctatt
     3361 cgatttattc aactctacct tatgatccca tttgcccctc ttacgattcc aacattttta
     3421 agtgatgaat ggaagtctat tggtattggc tatttaaaaa atattatggt ctatgcggta
     3481 caaggggttc tcatttttct gattgtttct cttgttcctt tgtttgaatc tgctgggaaa
     3541 atagctgttt caaatggtgc aggagtcttg caatcacttg cgattatgtt tggtagttta
     3601 gtacaagcta tcttactgat tattgccctc gttggttctc aacgtacggc tcgctcaatc
     3661 ttaggtatgt aattagataa aggctaggaa gtgattgctt cttagccttt ttagaaagga
     3721 aagtcatgaa tacacgtgtc tttaaagaca tctcaaaata ccaacacagg gcttggttag
     3781 gtttcaccac aagacaaatc atctttgttt taccagcctt tattgtcaca attattgttt
     3841 tgggcttgaa tctctttttc tggcaatttg gagattggtt tgtttacggt tttgtgtttg
     3901 cttttaccat ccccctaatg ctttttggag tctataaacc caatgattta tattttgaac
     3961 attatttgaa ataccgtctt cattttgaat taacggttcc cctacgcaca attacaggaa
     4021 agaaaggacc tgaacatgaa aagaaaatca aatacattaa agaaacaaaa aacttcaatg
     4081 actaataaaa aggaagaagt taaagggaaa aaagaggaag tgttaccctc aacggctaat
     4141 actctttcct atcaagccct gtatcaaaat ggtctgatgc aggtaaaaga agattatttc
     4201 tcacaaagct atttacttgg tgatgtcaat taccagaccg ttggtttaga agataagggc
     4261 gcaatcattg agaagtattc tgatttgatt aactcactag atgaccaaac caacttccaa
     4321 ttgactatct ttaataaaag attgaattta gaaaagttta gacaaagtgt tttgtatgag
     4381 gaaaaagaag atggatatga tacctatcgt aaagaattga atcggatgat gaatcagaat
     4441 ttagatagtg gtgaaaataa cttttcggct gtaaaactga ttagctttgg aagaaaggat
     4501 tctaatccca aacaagccta tcgttccttg tctcaaatag gagaatattt caagagtggt
     4561 ttctcagaaa ttgatgctcg atttgaatcc ttggctggag aagatcgtgt gaacttgttg
     4621 gccgacatgc ttagaggaga acaccatctt cctttttctt accgtgattt aacgagatct
     4681 ggtcagacaa ctcgtcactt catagcccct aatctcttgg attttaaaaa caagaattac
     4741 ctacaaatca atgaccgctt attacagatt gtctatgtca gagactacgg catggaatta
     4801 ggggatcagt ttattcgaga ccttatgcaa ggagatttgg aattgattgt aagccttcat
     4861 gctcaaagtt cgaccaaggc agatgccatg aagaaactac gaacaaagaa gaccttgatg
     4921 gaatcccaaa agattgggga acaacaaaaa ctagctcgta caggtatcta tttggaaaaa
     4981 gtaggtcatg tattagaaag taatatcgat gaagctgaag aacttttaaa aaccatgacc
     5041 gagacaggtg ataaactgtt tcaaacggtc ttcttgattg ggatctttgg tcaggatgaa
     5101 gaagaactca aacaagctct agatacgatt caacaagtgg ccggctcaaa tgacctaatg
     5161 attgataaac ttccatatat gcaagaagca gcctttaata gtttgctgcc atttggttgt
     5221 gattttttag agggagtatc acggagttta ttaacatcta atgtagcagt gaactcacct
     5281 tggacttcag tagacttaca agaccgcagt gggaaatatt acggtatcaa tcaaatctca
     5341 agcaatatta ttactattga tcgaagctta ttaaatacac cgtctggtct gattttaggg
     5401 acatctggag ctgggaaagg gatggcaact aagcatgaga ttatcacgac caaaatcaag
     5461 gaatctggtg aaaatactga aattatcatc gtggatccag aagcagaata cagtgtcatt
     5521 ggacgagctt ttgggggaga aatgattgat attgcgccag attcccaaac ctatctcaat
     5581 gtacttgact tgtctgatga aaatatggat gaggatcctg ttaaggtaaa atcagaattt
     5641 cttttatcct ttatcggcaa gttattggat aggaaaatgg atggaagaga aaaatcgatt
     5701 atcgaccgag tcaccagact cacctatcag tcatttaaag agccttcttt ggaagaatgg
     5761 gtctttgtct tgagtcaaca accagaagaa gaagcgcaga atttggcact tgatatggaa
     5821 ctgtatgtcg aaggttctct tgatattttt tctcataaga ccaatattca gacaggatct
     5881 aacttcttaa tctataacgt taaaaagtta ggagatgagc tgaaacaaat cgctcttatg
     5941 gtagtgtttg atcagatatg gaatcgtgtt gttcggaacc aaaaattagg gaagaagacc
     6001 tggatttatt ttgatgaaat gcagcttctc ttattagata aatatgccag tgatttcttc
     6061 tttaaattgt ggagtcgtgt cagaaaatat ggagctagtc cgactgggat aactcaaaac
     6121 gtcgaaacct tattgttaga tccaaatggt agacggatta ttgcaaatag tgaatttatg
     6181 attctcctca agcaagcaaa aaatgaccga gaagaactgg ttcaactctt aggcttgtca
     6241 aaagaactcg aaaaatacct tgtcaatcca gaaaaagggg caggactgat aaaagctggt
     6301 tcagttgtcg taccctttaa aaataagatt cctcaaggta ctcaattgtt tgatatcatg
     6361 agtacggatc ctgataaaat ggcttctaat taaggggaag tagaatgaag gataaaagaa
     6421 aaatcatacg tgcccgaaag gcatttagaa gaagcctaaa agatgagaaa aaattcttga
     6481 aaaaaggaaa gaaggaggta aggaaacaga aaaaagattc cgctgtactg gatgaaaaag
     6541 catggaaaaa agagataaaa gaaaagctag aggagatgag agaggcttca aaggagagag
     6601 taaaacaagc aaatgaagac tacaatcata ttcttcaaaa tagtcctcca tctcttttga
     6661 atcgcaaaga attaagagac agacggttgc ctcatgctag gaaacgattg aaaatagcca
     6721 agaagcaatt tagagaagcc aaggtagaag caaaagaaga aagaaaagag ggtcgtaaag
     6781 aaagaaaaac caatcaaaaa tttctctacg gtcaggaatc gaaagcaaaa tcaaattttt
     6841 tctttcaagg gaagagttta gaagaattaa aagctaagaa agaagtcaag gacgccaaag
     6901 aaaatttaaa atctactaaa caagcctata aatccaaaaa ggttagtagg aaagccaaaa
     6961 ctttccttta tgtccttgga cgtgaaggtg gagagttagc ttcagaaaat gaagatttag
     7021 aaggctatcg cacacttcaa gagaccatta gaaaagggaa acgctacagt cggctttctt
     7081 ataatcttgg aaaagctagt gtcaaaacag gacaagcaac aggtcgtttt accaagaaaa
     7141 gactgaccaa cacaaaagag cgataccatc attttaagga tggaaaagga tggaaactag
     7201 cgaaagataa tccaagttcc tttaaaaatc ggtatcgaaa attaaagaaa caaggcctta
     7261 caagtgtacg aaatatctat caaaaactaa aagcagcctt ttccttcttt acatttgcgg
     7321 ctgggaatcc tgcaacctgg atagttggag gaatagtctt tcttctttta cttatgatga
     7381 gcttcttttt aggattttca tctgctagtt taattcaaca agatgaattt gaattaacaa
     7441 aagcttatac ccacctaact tgggaagacg cagaacatac ccgaaccaat gacaaaggaa
     7501 ttacctatta cacaaaagtt gatgatgtga tggggtatat gaactttaaa ttccatgact
     7561 atgagttaca caaaccagtt cacttattta gttcagaaac ttacaaggat tatctatcta
     7621 ctttgtggca tgatttaaac gatggggaag atttgaaatc catgcaagac ctttatgaaa
     7681 ctcctaagta taaactatcg aaagacgatc aagaggaaat gaaggaacta aaagaagaag
     7741 gtgtgtatgc ttccatgcag gaattggaca atccatttga agggaaaagt aacgaagata
     7801 gtttaaccat gacttatcgt tatggatact atgatttaga cggaaaacct actcttcagg
     7861 agtacattct actagaagct aaagctcacc aagcaattgt cgcaccaatg gatggagttg
     7921 tatctctaga tggcgacaat gttattctca ctaacggaaa aggagaaaac gagagtcgct
     7981 taaccttata ttccattcat aatggccgtg cgattgaggg gacaagagtc ctaacgggtg
     8041 atgttattgg tgagacacca gatgatacag gtttgaaagt ttcctatcaa aagtataaga
     8101 acaagaaaga aaaattggtg tatgttaatc cgcaatttta ttttccaaaa gtcattcaac
     8161 ttcagacaac tatcttacct gccattggtc agtttggtgg ggatgagttt gaacgagcga
     8221 aacatattta tgagtttttg aaatctcaag gggcaagtcc ccaagccatt gcagctattt
     8281 taggaaattg gtcggtagag tcttctatca atcctaaacg agctgaggga gattatttat
     8341 ctcctccagt tggcgctacc gcttcctcat gggatgatga aacctggtta gcgattggag
     8401 gtccagccat ttatagtggt gcttatccta atatccttca tagaggtttg gggttaggtc
     8461 aatggacgga tactgcagat ggttcaacac gtcatacagc tttattgaat tatgcacata
     8521 gcaaaaataa gaagtggtat gatttagacc tccaacttga ttttatgctt catggggata
     8581 gtccttacta tcaaagttgg ttaaaagatt tctttaaaaa tacgggcagt gcagccaatc
     8641 tcgcccaact cttcctcacc tattgggagg gaaattctgg tgacaaacta ctggaaagac
     8701 aaaccagagc aacggaatgg tattaccaaa ttgaaaaagg cttcagccaa acaaatggag
     8761 gacaggcaaa aagtgaccca caatcccttg aaggggttcg tggggacttg tatgatcatt
     8821 ctgttcctgg tggtggagat ggtatggcct atgcctatgg acaatgtaca tggggcgttg
     8881 cggctcgtat gaaccaatta ggcttaaaat taaaaggaag taatggagag aagatttcaa
     8941 ttattaatac catgggaaat ggtcaggact gggttgcgac agcttcaagt cttggtgggg
     9001 aaactggctc tacaccaaga gcaggtgcca ttgtttcttt tgtgggaggt acacatggta
     9061 caccagccat ctacggtcat gtggcttttg tcgagaaagt atatgatgac ggttctttcc
     9121 ttgtgtctga aaccaactat ggtggcaacc ctaactatac ctttagaaaa atctctcaag
     9181 cagatagtgc aataagtttt gcctatacta cgaaatagaa gagtttacac ttgaaatttt
     9241 aaccattttc aggtagaata aatagtgtag atgagtagtc ggctcatggt caatctgata
     9301 gtaatcttgg acataagggc caagcggtgg cggacaccag aacgaaatcc gatagcaatc
     9361 ttggacgtaa gggccaagcg gtggcagaca ccagaataaa ccgactgact aggtggctta
     9421 cagactctgt aaaccacctt ttttgtgagg aaaatatggc aaattctaga gattatcgta
     9481 atccaaatta caccgaaaaa ataaaacttc agcgtttttt tactcagtta caaattgcgg
     9541 cttctttttt taaagaacac ttcgttggca aaatcatgta ttatgaaaca gaaatagaaa
     9601 gtgttgaact tcatttttca cctactaatt tcatgcacct atgtggtgtt gattaccaaa
     9661 aaggtgcagg tagtttcttt gacgattgtt taaatagaca tgtcataatt gatgagttga
     9721 aaataaaaaa agatggaacc acgatgcaaa agttacaagt tttaggatcc attgaggagt
     9781 tattgggaaa gcatgttcat ctaactggtt caggacgtta tttgtatttg gagtttgatt
     9841 atgctctacg tacaagaaaa cagatactag cattaacatt gaaagagaca tcaaggaaaa
     9901 ttgttcctca atctttatta gatttgaaga gaaagacagt atttccaaaa ggtcaaaaag
     9961 taatttcaat ttactcaaaa catttacaaa cgtcggaact tttttattat ttaaaagatt
    10021 agtttacata tcttttgtgg cataaaatat atttttatca ttttcaggag aacgcagttt
    10081 tggctcgttc tctttttttg ttgtgatact tctttcaagg aatatttggt aggattggag
    10141 tgaaaaaaga ttaactagga aagaaggaag tatatggaag gcatttatca acgtgattcg
    10201 gatcaagatg gattaactga tgctcaagaa ttggcgctag gaaccaatcc tcttagcgca
    10261 gattctgatg gtgatggacg ttcagattta gtggaagtag aagaaggaac caatccctta
    10321 gaaaaggatt tacaagacat agaccaaaca agtataactg aaccgtcttc agtatttatg
    10381 gaaatgaaac aaaagatttc agatatgatg gagagtcact acaaggaatt tatacaggct
    10441 cttattagta ttgaaacagg gattgaaaac gaacaagacc tagaagactt atatacttac
    10501 tacatgagaa cagattctat ttctcttttg tctagtgatt tagaaaccag tcctcaaaag
    10561 gttgaaatgg agatagagtt gtaggggaat catgtgattc tcctattttc gtatagatga
    10621 aaggagcgag tatggaagta atgaaattat tggctatgtt tcgtggaaca attccaaaag
    10681 atagggagaa aatggaccta tttcttcgct atcaggcgca acattttgat gagaaatggc
    10741 aggacttggt agagagtttt ttggttgaag agggcaagat agaagagata cctcatgtgt
    10801 attcgtttca tcaagatatt atttctttcc tagaggctag ttctgaaaat aatgaccaag
    10861 atttagaaag ttacacaaga aattttggac aagcaggtct aagtaaatta tctcaattaa
    10921 gtaattttga gaaaaacttg gtgctagaag tcgcaaccta taacctttcc actcgatttt
    10981 atatccaatc tgaaaaagag aaactaacac cattaagtga gcttgtatgt catcagaaac
    11041 aggatgtcaa tttagtcaat gtctatcggg ttgcgaataa tctatctgac cgcattagta
    11101 gagatataga ggagtttctt ctaatggttg actcaaaaga gcttaaaaaa gaagttcttg
    11161 agattcattt tgaagaaaaa gagggagatg ttctagctta tttgggttca gaattgatgg
    11221 ctactttaga tactgttacg gatcttgtcc atcatgaaga aaactaccaa caacttccac
    11281 tgacacaaaa gctgaagatt attactcatt ttgatgaagt aaaggctata agagaaaagt
    11341 ctaagcaagt agcggaatcc ttatctcctt caagtgatat tgaacaggaa acggaagaaa
    11401 cgaactcctt ttctaatatc gataaaattg tagaagaagc tttgagggaa tatccaatcg
    11461 gttcacaagt aagttataaa ggacaagtat ttcagttggt ttcgattgaa aatgcacagt
    11521 taaatgactt agttcgccta gagctattca aagattccaa ccagttattt gaagagaatc
    11581 ctatcttata cttgaacagt ttggaagaga ttgaacaagt attgtctcat gtagaacttg
    11641 aaaaagaaga ttcagagatt gagattgatt catcaagtga aagtcaggaa atagatttgt
    11701 tttcctacct ggaagaagaa aatgaaaatg aaaaggaaaa ggaaaaggat aaagaaacag
    11761 aaacgcttat tgtaggcata gaagagacgg atgtccctgt tcaagatttt gtttttccag
    11821 atgatttaga ggacttttat cctaagacaa atcgagaaaa aattgaaacg aatatcgccg
    11881 caattgaact tgttaaaaga ttagaaaaag agggacgaca agcgaatcca gaagaacaag
    11941 agctactagc caagtatgtc ggctggggtg gtcttgccaa tgaatttttc gatgaactca
    12001 atccaaagta tgaaacagaa cgtttaactc ttaagagttt agtaagtaaa tcagagtact
    12061 ccactatgaa acaaagttct ctcacagcct attatacaga cccaatgatt attcgccaga
    12121 tttggcaaaa attactggat gatggttttg agggaggaag gatattagat ccttctatgg
    12181 ggactgggaa cttctttgcg gcgatgccta gaagtatacg agataaatca gaactctatg
    12241 gagttgaatt agacagtgtg acaggcgcaa tcgcaaaaca actccacccc aatacccata
    12301 ttgaagtgcg aggatttgaa gaagttccct atcaaaataa tagttttgat ttagtcttaa
    12361 cgaatgttcc ttttggaaat tttcgcattg ccgataaaaa ctatgataaa ccttacatga
    12421 ttcatgatta ctttgtcaaa cactcacttg atttagtaag agacggagga caagtgtcga
    12481 ttatctcatc tatagggaca atggataagc ggacagataa tgtcttacaa gagattaaat
    12541 ctaacactca ttttttaggg ggagttcgtt tgccggatac ggcttttaaa aagattgcag
    12601 gtactcgagt gaccacagat cttctcttct ttcaaaagga tcaagcaaag aatcttaatg
    12661 aggaggaact tgtctttagt ggctctattc cctttgaaga ggataagcgt gtctggatca
    12721 atccttattt tgatgggaaa tacaatacac aagttttggg tcaatatgag gtgcgtaatt
    12781 ttaatggagg aactctcaat gttaaggggg tatcagaaac attagttact gaaataatga
    12841 aagcattcga gaatgtggaa gcacctaaac aaattgacaa ttctttgaaa gcacctgttt
    12901 ttatccaaga agaagtagat aattctatcc caagtcgtat atgtgaggac ttagcgctct
    12961 attcttttgg atatgaggga aatcaaattt attaccgaga tacgcatggc attcggaaaa
    13021 gttcaaaagt agacgaaatt agttattatg tagacgagaa gggagaattt aaagcctggg
    13081 acagttcttt gtctgaacat aaaatagatc gattcgtgca acttcatttg acagatgagg
    13141 aagcactaga tgtatacaag tcagaagaag cgagtaaaag agggaaatat aagggactgt
    13201 tcaaaaaaac tgtcttttat gaaagtccct tatcggataa ggatattagt cgcattaagg
    13261 gtatggttga tttgagagag acctatcaag ccttaattga aattcaacgt catccagatt
    13321 atagtcggtc tgattttcag atattactta gtaaactcaa tcgtgattat gaccgttttg
    13381 taagtcaatt tggatacttg aatgcctcag ttaatcggaa cttatttgat agtgacgata
    13441 agtattcttt actagcaagt ttagaagatg aatacattga ttctaaagat cagaaagtaa
    13501 aatataaaaa atctttagcc tttgagaaag cattggttag gccggagaga gtgattacaa
    13561 gagtatcaac ggctttagat gccttaaact ctagtttatc ggatggtaga ggggttgatt
    13621 tagactatat ggtatcaatt taccctgaac atagtcaagc tgctatttta gatgagttag
    13681 gtgaccagat tttaatggat ccagaaagct atttaagagg tgaaagaaaa tatctttcta
    13741 agaaccagtt tttatcagga gatattctca acaagataga agtagttcaa ctattagtag
    13801 aggaaaacaa ccaagaatat gattggaacc atgctttaga tttgttagaa tctgttcgcc
    13861 ctccaaggat tcatctggca gatattgagt ttaaaatagg gtcacgttgg attcctcaat
    13921 ccgtttacgg taaatttgcc tttgaatgtt ttaccaatcg tgaatttgaa ttgtcttcac
    13981 ctgatgttga acaagttatt gaagtgaatc ctgtcgatgg gcaggttcat ttaaggacat
    14041 catttgctta tcgctatcca agtgccaaag atagtagtct tggagttagt gggtcacgtt
    14101 atgatacagg aagaaagatt tttgagaatt tacttaattc gaaccaaccg acgattacta
    14161 tgactgttac ggaaggagaa aagaaaaaga ccatcacaga tttggaaaaa acctctgttc
    14221 taagagcaaa agagcagcat ttacaagagc tctttcaaga atttgtctca cggtatccag
    14281 aagtccaaca agttattgag gaaagctata atcgtcttta taatcgaacg gtaagtcgag
    14341 agtatgacgg tagccatcta gtcattgatg gattggcaca aaacatcagt cttcgtcctc
    14401 atcaagagaa tgccattcaa agaatcgtag aagaaaaaag agccttgtta gctcatgagg
    14461 taggttcagg aaagaccttg accatgcttg gtgctgggtt taaattaaag gagttgggga
    14521 tggttcataa gcccttgtat gtagtacctt ctagtttgtc tgctcaattt ggccaagaaa
    14581 tcatgaaatt tttccctact aaaaaagtct ttgtgactac taagaaagat ttcgttaagg
    14641 caagaagaaa acaatttgtg tcacgtatta ttacaggaga ttacgatgcc attgtcattg
    14701 gggattctca atttgaaaaa atccctgtca gtaaggaaag acagatgaat tatatcgagg
    14761 ataaactcaa tgaattacga gagattaaaa cacattctga aaataagtat actgttaaag
    14821 aagcagagca atcaataagt ggtctagaga aacaattgga agaactccaa cgctttaatc
    14881 gtgatagttt tattgatttt gagaacttag gaattgattt tctctttgtg gatgaagcac
    14941 atcactttaa aaatattcgt ccaattacgg gacttgggaa tgtagcaggg attaccaata
    15001 caacctctaa gaagaacgtg gatatggaaa tgaaggttcg acagattcag gaagagcatg
    15061 attttaaaaa cattgtcttt gcgacaggaa cacctgtttc caattctatt agtgagttat
    15121 atactatgat gaactatatt caaccagata tcttaaaacg ctatcaagtt gattattttg
    15181 actcttgggt aggtgctttt ggagaaattc aaaactctat ggaattagct cctacagggg
    15241 ataagtatca gcctaagaaa cgatttaaaa agtttgtcaa tctacctgag ttgatgaaaa
    15301 tctataaaga aacagccgac attcaaacac aagatatgtt ggatttacct gtaccagaag
    15361 cccatattat ccctattgag agtgagttaa ctgaaaacca gaaactctat ttagaagaat
    15421 tggttatgag gtcagatgcg gtcaaatgtg gaacagttga tccgagccag gataacatgt
    15481 taaagattac gggtgaggca cggaaactag ctattgatat gcgtttattg gactctagct
    15541 atagtctagc agacaatcat aaactgcttc aggtagttga taatgttgaa agaatttatc
    15601 gtgagggaat gggaaataag gctactcaga tgattttttc agatattgga acacctaaga
    15661 aaaaagataa tggctttgat gtttattctg aaataaaggc tttattggtt gatagaggaa
    15721 tccctagtaa ggaaattgcc tttgtacatg atgccaatag tgatgaaaag aagaatagtt
    15781 tgtctcgaaa ggtcaatgca ggagaagtgc ggattcttct tgcatcaact gaaaaaggag
    15841 gaacaggttt aaatgttcag agcaagatga aagcagttca tcacctggat gttccgtgga
    15901 gaccaagtga cattcagcaa cgcaatggac ggattatccg acagggaaat gaaaacaagg
    15961 aagtggatat ttaccactat attaccaaag gttcgtttga taattatcta tgggcaactc
    16021 aggagaacaa actccgttat attaagcaga ttatgacttc taaggagccg attcgtgctg
    16081 cagaagacat tgatgagcag accatgacag cttctgattt taaggcacta gcaacaggta
    16141 atccttatct caaatataag atggaactag agaatgatct aactctatta gaaaatcaaa
    16201 gacgcgcctt tcaacgcagc aaggatcact atcgtcatac aatctcttac tgtgaagaaa
    16261 atatgcccat tcttgagaaa cgattaagca agtatgaagg cgatattcaa cagtctgaaa
    16321 tatcgaaaga ccaggcattt tctatgacgg taggtaagca agcttttgat caacgagctg
    16381 aagcaggtga atctctacac cgtcttatcc gtcataatca agctgacagc aaagaatttc
    16441 gtaccctagc aagctatcga ggatttgaca ttaaaatgct tagtcttcca ataaatcaac
    16501 ctcttcctga aaccttctct gttaagattg taggagaaaa tcagtattct gtcagtttag
    16561 atttgtattc tcctttgggg acaattcaaa ggcttcagca tacaattgat cacattaaag
    16621 aggaccaagt gaaaactcag aacttattgg atgaattaaa ggataaatgg actactgcta
    16681 aagttgaaat tgagaaaaat tttccaaagg aagaggatta tcaaactaaa aaggccgaat
    16741 acgatgtact cgcgccattg attgaaacag aaacggattt agatattata gatcaggcct
    16801 taagacaatt ccacgaaaaa ggaaaagaaa agcaagaaca actttctttt gaattagatt
    16861 aaaaaatata tataaatagc ggacaagaaa agaaaagcgc ggtagaataa agatagaaag
    16921 aaacgaggta acgattatga tggaagatac ctattatcaa ttagaagagg ccttggtaca
    16981 gggatttcaa acgcctgaag aataccaagc ctacaaggag ctaaaggaac attatgagga
    17041 agtgacaggc gattacagtt tttctaaacg agaactcact agtcaattgg aaatctctct
    17101 tcagaatcat cgaggtgtgg actttgaaga acatgaaaaa gaggagtatt tggacttagt
    17161 tcaaaaatta gaagagtttg attcctctct tgccacccat tatcgtcaat tgattgacta
    17221 gaaaggagaa agtcatgaat gatttactcc ttatcccagt aattttttta gcagtaggag
    17281 ggattctcat tcttttatgg agactctttc ttattgccag tagacttttc ctgattggtt
    17341 ttgtcagttt tcttattttc gtagaagtct atggaattta tctgttcttt actgaaccta
    17401 ctttatattt tgatgatatc agacaacatg gtttaactag ttttacggct gtgtaccttt
    17461 tcatcaatct gatgttggtt ctaggattca gttggcgctt cattaactcc atgaataagg
    17521 aaaaaatgtg aactttttag atagttaaaa gactttatct gaatctaaat tcggataagg
    17581 ttttttattt gccttgattc tttcatatac ttcatagcta aattggagta ataatttatg
    17641 aaaatcatta tcctcactat tattagttgt atttatggct tgtttatgtc gttcaatatg
    17701 agaaagagct cttctcaaat tttcttcttt taatttgttc atatttatat tataaactga
    17761 agacagctgg ttttgacatt tttctctgaa ctgtacgatt ttgcgccaga aatgtaggaa
    17821 ttacctttcg ttgtgatgtg ataaaactta caagttcttt ttgttattct tgacctagtt
    17881 tttatagaaa gaaggtctaa gatgttaaat aaagtcaaaa ctaaagcctt aattagtgtt
    17941 ggagcagtgg ctgcaactag ctttattctc atgatgggat atactgctgg tcaacactca
    18001 actgctaaac aaagtcgcaa agaaatcgaa ttggctgcag ctaaacttgt agaggataaa
    18061 caagcagaag ataaagccag cattttgtca tcggatactg taaaagaatt tttgactcag
    18121 tactatacga aagaaaagct cggagaaaat aatacacgta ttcaacctta tatgactgaa
    18181 tcggcatatt ctcaagaatt gaccagtcaa aacgatgcca tgaaccaagt gtataaggac
    18241 tatattttgg attatcattt tgaaaaagct gatatctttg ttaatcagac tacgaatcaa
    18301 gctattgcca tggtctctta taatgtaacc tatgtatctg atttaaagaa tgccaaccaa
    18361 tcaaagacta atcagacaga aacaagaaca gttaagttat cctattctaa actaccaggt
    18421 aagttattgg tcaatcaagt gcaggtttgg aaatctgggt tagatgattt agataaggta
    18481 actcctaaaa ctttagaaga atcatcatca ataccatcac tgccaaatac tacgacaaaa
    18541 tgatgatatt gcatggaaat agaagaatgt aagcaaattt caattcttga tgtagccaat
    18601 cgtttaggta tctcctttaa acaagtttct agccgtgtct atgaacatcc tgaacacgat
    18661 tcatttcgga ttttttcaac taccaatact tttaaatggt tttcaagaga tattcaaggt
    18721 gatgttattg attttgttcg acttgttaag ggaatctctt ttaaagatgc tctagctttt
    18781 ctttctgaag aaccttttca aaaagaagct gttcaagaaa aaagagagag accattttat
    18841 tatcctttaa agagagtaga agattctaac tgtagtctgg caagatatta cttaacaaaa
    18901 tgtagaggaa tctcagaaga aatcgtacaa aagatgattc aacaaggttt gatggcacaa
    18961 gccagttgga aaacaaatga aactgttgaa cttgttattg tttttaaaag ctttgatcat
    19021 cgtcacaagc tgcaggcagc aagcttacaa gggatttata agaatcccgc tctttctaga
    19081 gagaggttaa aaacgattct aaaaggaagc catggacata ttggaatatc ctttgacatt
    19141 ggtaaaccaa atagactggt cttttgtgaa tcgttcgtcg acttgatgag ctattacgaa
    19201 cttcatcaac aaagtctaac tgatgttcgt ttggtatcta tggagggatt aaaaaggtct
    19261 gttgtcgctt atcaaacttt acgactgata gctgaagaaa atcagaagtt ggaattttta
    19321 gatacagtaa taccttcaaa gttattgcct ttgatgaata caattcgaga tacaactact
    19381 tattttgata atcatcccga tttattaaca cttgcggtag attgtgatga tgcaggaaaa
    19441 gatttttccg ataagttatt tcaagctgga ttgcctgttt tactggattt acctgataac
    19501 gaatctggga aagaaaaaat agattggaat gatatcctta gagaaaagaa atcagattta
    19561 caattgatac ttgagtctgc aaaagagaca ttgaggaatc aaccagtaag acaaacctct
    19621 caatgtttag aattgtgata acaaaatcaa gatgttttag ctaatattag aatgaaggag
    19681 gatagtatat gaccattatt gaacgcttag aagaaaaggt cactaggcaa gaaagtaagg
    19741 tagcaagaga gacagaaaaa ctagctgctt acaaagagca actggagaca gcgatgtttg
    19801 cgacgttcaa aaggcgtcaa agcattagtc acatgagttt tgaagaagct cttgaccatg
    19861 cctttggtaa agaaagacaa ttcgatgatt ctgaatttag aaaggatgaa atgagtgaat
    19921 gacaaaagat tggaatttta atcaaccatt agaaagtaaa tcagaaaatc aagaagatcc
    19981 agataaaatt gcggctttat ttagaaatca tcaaggaggt aatgatgtaa attatgaagc
    20041 agcttttcaa aagcgtaaac aagcacctgt gacggaatca aattctagtt ctaaacccaa
    20101 agttacagag gttagaacag gaaaagagac agatatcact acaagttatc agcaacatct
    20161 taaaagactg attgcggata acaatagcga tattgaaagt agtcaaaaga aaattgaaga
    20221 gctacatacg ttgattgaca caaagaataa agacaataag aaattgcagt ccatttatga
    20281 tgcgatttcg gaattacact aagcagtcta aagaggctgc tttttttgag aggttataga
    20341 tgtttacaaa aatttttaag aaaaatcaag acaatagtga tatatttaag aagttgattc
    20401 atagactatc tgatatgtct gtccaagatc ttgaaaaaat tgacagattg ttagatatca
    20461 ttttcactcc agaacaagaa tcagaacaac taaaaacaga aacaacttat agggaagaaa
    20521 ctttggacga cacattaaaa aaagctaaaa atcaacttca taaggaacaa ttggagaaga
    20581 atttagagag atttaggaaa aatagtcaat aacgcaccaa aaatggtgca tttgcttttt
    20641 ctaaatgtta taatggtggt atcaaataaa aggagtttgc catgattgga aagaacataa
    20701 aatccttacg taaaacacat gacttaacac aacacgactt tgcacggatt gtaggtattt
    20761 cacgaaatag tctgagtcgt tatgaaaatg gaacgagttc agtctctacc gaattaatag
    20821 acatcatttg tcagaagttt aatgtatctt atgtcgatat tgtaggagaa gataaaatgc
    20881 tcaatcctgt tgaagattat gaattgactt tgaaaattga aattgtgaaa gaaagaggtg
    20941 cta
//
LOCUS       DAVBOH010000035        20670 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOH010000035 DAVBOH010000000
VERSION     DAVBOH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.035"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(2..1681)
                     /locus_tag="VQ873_001478"
     CDS             complement(2..1681)
                     /locus_tag="VQ873_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3107727.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1683..1916)
                     /locus_tag="VQ873_001479"
     CDS             complement(1683..1916)
                     /locus_tag="VQ873_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3107728.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ873_001480"
     CDS             complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ873_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3107729.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ873_001481"
     CDS             complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ873_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3107730.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ873_001482"
     CDS             3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ873_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3107731.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3919..4356
                     /gene="rimI"
                     /locus_tag="VQ873_001483"
     CDS             3919..4356
                     /gene="rimI"
                     /locus_tag="VQ873_001483"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3107732.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ873_001484"
     CDS             4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ873_001484"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3107733.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5396..6702)
                     /locus_tag="VQ873_001485"
                     /pseudo
     CDS             complement(5396..6702)
                     /locus_tag="VQ873_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7036..7330)
                     /locus_tag="VQ873_001486"
                     /pseudo
     CDS             complement(7036..7330)
                     /locus_tag="VQ873_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7437..7730)
                     /locus_tag="VQ873_001487"
                     /pseudo
     CDS             complement(7437..7730)
                     /locus_tag="VQ873_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7973..9177
                     /locus_tag="VQ873_001488"
                     /pseudo
     CDS             7973..9177
                     /locus_tag="VQ873_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9170..10046
                     /locus_tag="VQ873_001489"
                     /pseudo
     CDS             9170..10046
                     /locus_tag="VQ873_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10133..11749
                     /locus_tag="VQ873_001490"
     CDS             10133..11749
                     /locus_tag="VQ873_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107734.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11769..12612
                     /locus_tag="VQ873_001491"
                     /pseudo
     CDS             11769..12612
                     /locus_tag="VQ873_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12680..14181
                     /locus_tag="VQ873_001492"
                     /pseudo
     CDS             12680..14181
                     /locus_tag="VQ873_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14193..14942
                     /locus_tag="VQ873_001493"
     CDS             14193..14942
                     /locus_tag="VQ873_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3107735.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14955..16127
                     /locus_tag="VQ873_001494"
     CDS             14955..16127
                     /locus_tag="VQ873_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3107736.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16522..17385
                     /locus_tag="VQ873_001495"
     CDS             16522..17385
                     /locus_tag="VQ873_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3107737.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17671..17904
                     /locus_tag="VQ873_001496"
     CDS             17671..17904
                     /locus_tag="VQ873_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107738.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17926..18603
                     /locus_tag="VQ873_001497"
     CDS             17926..18603
                     /locus_tag="VQ873_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107739.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18615..19280
                     /locus_tag="VQ873_001498"
     CDS             18615..19280
                     /locus_tag="VQ873_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107740.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19352..20578
                     /locus_tag="VQ873_001499"
     CDS             19352..20578
                     /locus_tag="VQ873_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3107741.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6467 a         3224 c         4172 g         6807 t
ORIGIN      
        1 attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt
       61 catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat
      121 ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca
      181 agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa
      241 tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat
      301 cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga
      361 tatcttgggc gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat
      421 cgccattgct catgataaag atattgtcct tctcaacacc agtatccact gctagtccag
      481 cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca
      541 agcggagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca
      601 ctttaccgtg gataacttcg acaccagctt cagaaataat gttaatcagc ttgttgacgc
      661 tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcgcct ggttggagtt
      721 gtacctgacg gtgggttccg ttggcgatac gagagagggc tgccataggt tcaccttgac
      781 tacctgtaca gaggatcaga atctcacctg caggatagtc tttgatttca tttggctcaa
      841 taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca atggcctttt
      901 ccatagagcg accaaagacc gcaatcttgc gcccagtctt aacagcagct tccgttgctt
      961 gttggagacg gaagatattt gaggcgaagg atgcaaagat gatacgtccc tcgatacctt
     1021 ggataatctt catgatggac tggccgacaa ccttttcaga gttggtaaag gttggaacct
     1081 cagcattggt cgagtcagag agcaagcaaa gcactccatc ttcacctagg gctgccatac
     1141 ggtgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca cctgtacaga
     1201 tgattttccc ttgaggagta tggatgacaa ttcccaaagg ttctggaata gagtgagtcg
     1261 ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt
     1321 aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg
     1381 caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga atcccaccaa
     1441 tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtctacga
     1501 tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa
     1561 tcccagcatc gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga
     1621 tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca
     1681 tattagaact ccgtaatttt gaaggcgcca gtttcttttt cgtaatcgag caatttgtca
     1741 gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga
     1801 gcagcgatac gaccctcaag ttctgagctg gcatcgatgt ctaggtaaag cgcgcgtgtt
     1861 gtttcacgac gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag
     1921 ttcctttcta tttacaggtc agcttattcc aaacttttag cagagatttg cttgatttca
     1981 ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa
     2041 tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaagcgtt
     2101 tgcaaaaaca aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata
     2161 attccatata gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta
     2221 tcggagttcg tttgctagct tttatcgttt ttgttgcttg cgtttatgga ggaaatcttc
     2281 tatttgccaa actggaacga tgacaaacca agttcttgag gaaaattacc tttgtgactc
     2341 tctactcgct ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttggat
     2401 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     2461 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     2521 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     2581 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     2641 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     2701 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     2761 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     2821 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     2881 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     2941 tagctttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     3001 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     3061 ttgaattttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     3121 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     3181 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     3241 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctcgctattt tagaggataa
     3301 gcagattctt gccgagatga cgattaatat taagaaaaat cacagtatta ccctcatgcc
     3361 tgccatcgat tttttgatgg caagtttgga ctggacaccc aaggatttgg accgaatcgt
     3421 ggtggctgaa gggccaggta gctacacagg cttgcgaatt gcggtagcca ctgccaagac
     3481 tttggctcat actctgaaca tcgagttagt tggtatgtct agcctcttgg ctctggtacc
     3541 ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg cgtcgcaaca atgtttatgc
     3601 aggattttat gaaaatgcta aacccgtcat gccagaagct cacttaccct ttgagcgagt
     3661 gattgagtta atcaagggtg ctagtcaggt tacctttgtc ggagaagttg gcccctttgt
     3721 tgagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
     3781 taatctagct ctatgggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     3841 ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag aatcacaccg agtctggcga
     3901 gtcttacatt aaacgcttat gatagaaatc aaacgaatcc aaaaacatcc tgacttggct
     3961 caagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     4021 atccaagcag acctgtccca agaccagact tggtatgctt tggcttatga tggggcagaa
     4081 gtgattggat ttctagctgt gcaggagaat ctttttgaag cagaagtcct gcaaatcgct
     4141 gtcaaaggag cttatcagag tcaggggatt gcgtcagcct tgtttgctca attgccgaca
     4201 gacaaggaaa ttttcctcga agtcagacag tcaaatcaac gagcgcaagc attttacaag
     4261 aaagaaaaga tggcagttat cgctgagcga aaggcctact accatgaccc agtcgaggac
     4321 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     4381 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     4441 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     4501 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     4561 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     4621 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     4681 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     4741 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
     4801 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     4861 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgatctgg ctcatcaggg
     4921 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     4981 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     5041 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     5101 aaaaactaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     5161 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
     5221 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
     5281 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
     5341 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
     5401 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
     5461 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
     5521 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
     5581 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
     5641 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
     5701 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
     5761 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
     5821 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
     5881 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
     5941 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
     6001 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
     6061 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
     6121 gaaatggttt cgaatcaccg catgagttcg tccgtctaaa attgcgagga tggatttgga
     6181 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
     6241 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
     6301 gacggtggaa gttgagcccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
     6361 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
     6421 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
     6481 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
     6541 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
     6601 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
     6661 ttccaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
     6721 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
     6781 tataattcct ggggtgggat tacccactac agaaattata gagccaaagc attccaaagt
     6841 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
     6901 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
     6961 aaaactggag gattttttta tgtccccccc atcgtcccat cgactgttcc gtagctgccc
     7021 aataacggag tataatcagc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc
     7081 gtaatttgac aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga
     7141 ttatactcgg gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt
     7201 tcattctgtg aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta
     7261 gtaagaattt ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca
     7321 tcggagccat agtatattga aacaaaaaag ggcattagta cttctataac agtatcgcaa
     7381 tctctggtgt gcgttgtctc gatcttaatt caaataatta tatcttcttc cagagagact
     7441 aactgcctgc tcaaggctcg atcatattcg agataaaaat aggtctcaac ccctgtctca
     7501 taaatataaa taggagtcag gtagcttaag tgattcaatt ctttaaggaa ccgatttact
     7561 ttttctgggt cttgttcgca gtaggtacgg ctctttttta gactatatcc catagccttt
     7621 agagcgtaat gaatagttgt tggaggacag ttgaattcag cagctatttc agtcaaataa
     7681 gcatcgggat gagtttcaat atagattttt aatttatctc tatcaatttt ttcaattaat
     7741 agtggaagtt tttttgaagt tagtgtattg aaacgttttt atacagtgct aaaatttgaa
     7801 gtgtagtgca gatgtatttg taatagtatt atagcaattc tttggagaag gtcgagacaa
     7861 gataaaatag gtatctttga gatataagca tgatttacta taaaattatt gagttattca
     7921 taaaaatttc tctatcaaat atcataatgc gtcgtttaag gagatggtta caatgcaata
     7981 tagttgtgga aaaataaata ttaatatccc tgatggatat ggagacatta aggatatagt
     8041 gttttcggct catattatag ttaggtataa taatggacat tgtggaggta tagatccgca
     8101 tataattgga ctttgtaaaa agcagatcag aaggatgtct ctatatccta ttttgataat
     8161 cgtatctaga gattcaaagg ttattgatga ttataaaaat ttagatattg cctatgttga
     8221 ttgtactcaa tgttcaaata attttgaaac tgccttacac gttaaaaata ttttaaaatt
     8281 attaaaaatc caacttatac actgtcatgg ctactcaact aattattttt tatatatgtt
     8341 aaaaaaactt gacaagaatg gatttggaaa ggttaagaca gtgataacat gccatggatg
     8401 ggttgaatat aacttaaaaa agaaattctt gacttatttt gatttttgga catattctat
     8461 gggagatgct tttatttgtg tatctgaaac tatgaaaaaa agattggaga gtataataaa
     8521 aaaataagaa gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg
     8581 tagtaggtgt tcaagacttt aaaaaagaat tttgtattcc aaataacaaa aaatcatttg
     8641 ttatgttgga aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
     8701 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
     8761 tgctttgaaa gaaaaaattt gctatttgaa atgtagagat aatttcaggt tacttggtga
     8821 aatctatcca gtactatagt ttaccaaata tcggatttat tgtatattcc ttctgataca
     8881 gaaggaatat ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt
     8941 aatgttggcg ggttaagtga aattattgaa catagggttg atggattttt atttgagaag
     9001 gaagatgttg agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg
     9061 aaatatgtag gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg
     9121 tttgtagaaa ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa
     9181 tatagatcaa gaattagtaa gtattataat accaacacat aataggtatg aatctctgat
     9241 tagagctgtg aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taattattga
     9301 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
     9361 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
     9421 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
     9481 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
     9541 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
     9601 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
     9661 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
     9721 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
     9781 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
     9841 aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt
     9901 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
     9961 actatttaat aggagacaaa tgcaaggctt taaaagtaat caagaaggca agagaagaaa
    10021 aaatttttaa cgaatttctt ttttaaaata tatgttatta tatcattttg gttttttcta
    10081 ttgtatatat gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac
    10141 tattataaaa tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca
    10201 attattgcta atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat
    10261 gaatttagag cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat
    10321 attccttgac tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga
    10381 gattcgaaat agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa
    10441 atcatcagga acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc
    10501 ttttaaacaa ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac
    10561 tcttaatcac tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct
    10621 acttgtacca aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactaacca
    10681 aaatgaagct tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc
    10741 cttgaatctt ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat
    10801 ggttatacaa agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa
    10861 tatttttttt cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt
    10921 gaaaattggt actattgaag caataggagc actaacaggt gttattttta cagcgctagg
    10981 tgaattagga ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta
    11041 ttcaattaat ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag
    11101 agattttccg ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt
    11161 aaaaaactta aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg
    11221 aagcgggaaa tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga
    11281 attgcgattc tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt
    11341 tctatatgta gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt
    11401 ggaagaaaat tatactgatg aagaaatact acagtcttta gagcaagttg gtttgagtgt
    11461 aaaagatttt cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc
    11521 aggagggcag aaacaaaaaa ttactttagc tagagggcta attagaaata agaaaatagt
    11581 attaattgac gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa
    11641 gatattagat agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact
    11701 taaacaatat tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg
    11761 agggaaacat gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat
    11821 actttaatga tattgagtta gaagttaagt attcctctgt cgaagaattg tttataatat
    11881 gtgagaaatt attagataag aaaaaagtat cattttttta tgtatatgag aaacccttaa
    11941 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaata tcccaatctt
    12001 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    12061 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    12121 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    12181 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    12241 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    12301 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    12361 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    12421 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    12481 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    12541 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    12601 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    12661 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    12721 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    12781 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    12841 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    12901 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    12961 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    13021 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    13081 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    13141 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    13201 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    13261 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    13321 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    13381 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    13441 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    13501 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    13561 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    13621 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    13681 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    13741 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    13801 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    13861 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    13921 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    13981 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    14041 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    14101 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    14161 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    14221 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    14281 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    14341 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    14401 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    14461 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    14521 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    14581 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    14641 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    14701 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    14761 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    14821 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    14881 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    14941 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    15001 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    15061 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    15121 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    15181 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    15241 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    15301 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    15361 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    15421 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    15481 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    15541 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    15601 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    15661 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    15721 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    15781 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    15841 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    15901 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    15961 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    16021 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg gaccttgaag
    16081 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    16141 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    16201 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    16261 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    16321 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    16381 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    16441 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    16501 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    16561 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    16621 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    16681 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    16741 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    16801 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    16861 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    16921 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    16981 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    17041 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    17101 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    17161 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    17221 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    17281 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    17341 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    17401 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    17461 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    17521 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    17581 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    17641 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    17701 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    17761 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    17821 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    17881 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    17941 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    18001 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    18061 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    18121 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    18181 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    18241 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    18301 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    18361 atgacaagtt tatctaaagt taatagatac tatcttgatg ttcttgtttc cgctgccata
    18421 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    18481 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    18541 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    18601 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    18661 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    18721 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    18781 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    18841 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    18901 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    18961 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    19021 ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga aagaaatggg
    19081 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    19141 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    19201 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggtattggtc
    19261 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt cttggggaaa
    19321 gattcccatt tgaatttaaa aaggagttgt aatgaaagta tttcttcaaa atagagattt
    19381 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    19441 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    19501 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    19561 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    19621 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgat
    19681 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    19741 tagaattatt gggcaagatc atctggcaga agctattgga tttaaacagt caactgttag
    19801 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggtattc tatccatcca
    19861 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    19921 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    19981 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    20041 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    20101 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    20161 gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg gctatctgca
    20221 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    20281 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    20341 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    20401 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    20461 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    20521 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    20581 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    20641 caacagactt ttttctcttt tctgaatgtg
//
LOCUS       DAVBOH010000036        20661 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOH010000036 DAVBOH010000000
VERSION     DAVBOH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.036"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            165..2147
                     /locus_tag="VQ873_001500"
     CDS             165..2147
                     /locus_tag="VQ873_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107742.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2448..7751
                     /locus_tag="VQ873_001501"
     CDS             2448..7751
                     /locus_tag="VQ873_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3107743.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7918..10077)
                     /locus_tag="VQ873_001502"
     CDS             complement(7918..10077)
                     /locus_tag="VQ873_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3107744.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10074..10670)
                     /gene="recU"
                     /locus_tag="VQ873_001503"
     CDS             complement(10074..10670)
                     /gene="recU"
                     /locus_tag="VQ873_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3107745.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10736..11263
                     /locus_tag="VQ873_001504"
     CDS             10736..11263
                     /locus_tag="VQ873_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3107746.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11333..11662
                     /gene="gpsB"
                     /locus_tag="VQ873_001505"
     CDS             11333..11662
                     /gene="gpsB"
                     /locus_tag="VQ873_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3107747.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11683..12063
                     /gene="rnpB"
                     /locus_tag="VQ873_001506"
     ncRNA           11683..12063
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ873_001506"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12148..13305
                     /locus_tag="VQ873_001507"
     CDS             12148..13305
                     /locus_tag="VQ873_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3107748.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13318..14712
                     /gene="mapZ"
                     /locus_tag="VQ873_001508"
     CDS             13318..14712
                     /gene="mapZ"
                     /locus_tag="VQ873_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3107749.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14788..16212
                     /gene="gndA"
                     /locus_tag="VQ873_001509"
     CDS             14788..16212
                     /gene="gndA"
                     /locus_tag="VQ873_001509"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3107750.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16224..16913
                     /locus_tag="VQ873_001510"
     CDS             16224..16913
                     /locus_tag="VQ873_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107751.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17011..18030
                     /gene="cbpC"
                     /locus_tag="VQ873_001511"
     CDS             17011..18030
                     /gene="cbpC"
                     /locus_tag="VQ873_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3107752.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18148..19380)
                     /locus_tag="VQ873_001512"
     CDS             complement(18148..19380)
                     /locus_tag="VQ873_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3107753.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19540..20010)
                     /locus_tag="VQ873_001513"
     CDS             complement(19540..20010)
                     /locus_tag="VQ873_001513"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107754.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20177..20587)
                     /locus_tag="VQ873_001514"
     CDS             complement(20177..20587)
                     /locus_tag="VQ873_001514"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107755.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6424 a         3741 c         4633 g         5863 t
ORIGIN      
        1 ctagtctgga gatttttcaa tagacttcgt tattgggcgg ttacgatatt catatttttt
       61 gcaaagatgt tgtttgaaaa ataattttca aaaattctga aaattctgtt gacatctttc
      121 tgaaaagagt ctataatgga gagaaagttt taaaggagaa aatgatgaaa agttcaaaac
      181 tatttgccct tgcgggcgtg acattattgg cggcgactac tttagctgca tgctctggat
      241 caggttcaag tactaaaggt gagaagacat tctcatacat ttatgagaca gaccctgata
      301 acctcaacta tttgacaact gctaaggctg cgacagcaaa tattaccagt aacgtggttg
      361 atggtttgct agaaaatgat cgctacggga actttgtgcc gtctatggct gaggattggt
      421 ctgtatccaa ggatggattg acttacactt atactatccg taaggatgca aaatggtata
      481 cttctgaagg tgaagaatac gcggcagtca aagctcaaga ctttgtaaca ggactaaaat
      541 atgctgctga taaaaaatca gatgctcttt accttgttca agaatcaatc aaagggttgg
      601 atgcctatgt aaaaggggaa atcaaagatt tctcacaagt aggaattaag gctctggatg
      661 aacagacagt tcagtacact ttgaacaaac cagaaagctt ctggaattct aagacaacca
      721 tgggtgtgct tgcgccagtt aatgaagagt ttttgaattc aaaaggagat gattttgcca
      781 aagctacgga tccaagtagt ctcttgtata acggtcctta tttgttgaaa tccattgtga
      841 ccaaatcctc tgttgaattt gcgaaaaatc cgaactactg ggataaggac aatgtgcatg
      901 ttgacaaagt taaattgtca ttctgggatg gtcaagatac cagcaaacct gcagaaaact
      961 ttaaagatgg tagccttaca gcagctcgtc tctatccaac aagtgcaagt ttcgcagagc
     1021 ttgagaagag tatgaaggac aatattgtct atactcaaca agactctatt acgtatctag
     1081 ttggtacaaa tattgaccgt cagtcctata aatacacatc taagaccagc gacgaacaaa
     1141 aggcatcgac taaaaaggct ctcttaaaca aggatttccg tcaggctatt gcctttggat
     1201 ttgaccgtac agcctatgcc tctcagttga atggacaaac tggagcaagt aaaatcttgc
     1261 gtaatctctt tgtgccacca acatttgttc aagcagatgg taaaaacttt ggcgatatgg
     1321 tcaaagagaa attggtcact tatggggatg aatggaagga tgttaatctt gcagattctc
     1381 aggatggtct ttacaatcca gaaaaagcca aggctgaatt tgctaaagct aaatcagcct
     1441 tacaagcaga aggagtccaa ttcccaattc atttggatat gccagttgac cagacagcaa
     1501 ctacaaaagt tcagcgcgtc caatctatga aacaatcctt ggaagcaact ttaggagctg
     1561 ataatgtcat tattgatatc caacaactac aaaaagacga agtaaacaat attacatatt
     1621 ttgctgaaaa tgctgctggc gaagattggg atttatcaga taatgtcggt tggggtccag
     1681 actttgccga tccatcaacc taccttgata tcatcaaacc atctgtagga gaaagtacta
     1741 aaacatattt agggtttgac tcaggggaag ataatgtagc tgctaaaaaa gtaggtctat
     1801 atgactacga aaaattggtt actgaggctg gtgatgaggc tacagatgtt gctaaacgct
     1861 atgataaata cgctgcagcc caagcttggt tgacagatag tgctttgatt attccaacta
     1921 catctcgtac agggcgtcca atcttgtcta agatggtacc atttacaata ccatttgcat
     1981 tgtcaggaaa taaaggtaca agtgaaccag tcttgtataa atacttggaa cttcaagaca
     2041 aggcagtcac tgtagatgaa taccaaaaag ctcaggaaaa atggatgaaa gaaaaagaag
     2101 agtctaataa aaaggctcaa gaagatctcg caaaacatgt gaaataactg ttgcaaaata
     2161 taagaaagga tttagtattt ctcttgaatg ctgaatcctt ttttacattt gtaaagaaag
     2221 cttctaaatg tactgacccc caaaagttgg agcctctttt tgtcagaata gagaaaattt
     2281 ttgttaattt tacttgtttc ctattgcttt ctcagttatt atttgttata ttaaaagtat
     2341 aattattttt tatttatcag ggttaagcat tgcactttca gaggaaggag tattttttaa
     2401 aaaggaaatg taaacgcttg ctaaaaaatg aaaggattta gaagtttatg aataaaggat
     2461 tatttgaaaa acgttgtaaa tatagtattc ggaaattttc attaggtgtt gcttctgtta
     2521 tgattggagc tgcattcttt gggacaagtc cggttcttgc agatagcgtg cagtctggtt
     2581 ccacggcgaa cttaccagct gatttagcta ctgctcttgc aacagcaaaa gagaatgatg
     2641 gacgtgattt tgaagcgcct aaggtgggag aagaccaagg ttctccagaa gttacagatg
     2701 gacctaagac agaagaagaa ctattagcac ttgaaaaaga aaaaccggct gaagaaaaac
     2761 caaaagagga taaacctgca gctgctaaac ctgaaacacc taagacggta acccctgaat
     2821 ggaaaacggt agagaaaaaa gaacaaaagg gaacagtcac tatccgagaa gaaaaaggtg
     2881 tccgctacaa ccaactatcc tcaactgctc aaaatgataa cgcaggtaaa ccagccctgt
     2941 ttgaaaagaa gggcttgacc gttgatgcca atggaaatgc aactgttgat ttaaccttca
     3001 aagatgattc tgaaaagggc aaatcacgct ttggtgtctt cttgaaattt aaagatacca
     3061 ataataatgt ttttgtcggt tatgacaagg atggctggtt ctgggagtat aaatctccaa
     3121 caactagcac ttggtataga ggtagtcgtg ttgctgctcc tgaaacagga tcaacaaacc
     3181 gtctctctat cactctcaag tcagacggtc agctaaatgc cagcaataac gatgtcaatc
     3241 tctttgacac agtgactcta ccagctgcgg tcaatgacca tcttaaaaat gagaagaaga
     3301 tccttctcaa ggcgggctct tatgacgatg agcgaacagt tgttagcgtt aaaacggata
     3361 accaagaggg ggtaaaaaca gaggataccc ctgctgaaaa agaaacaggt cctgaagttg
     3421 atgatagcaa ggtgacttat gacacgattc agtctaaggt cctcaaagca gtgattgacc
     3481 aagccttccc tcgtgtcaag gaatacacct tgaatggaca tactttgcca ggacaggtgc
     3541 aacagttcaa ccaagtcttt atcaataacc accgaatcac ccctgaagtc acttataaga
     3601 aaatcaatga gacaacagca gagtacttga tgaagcttcg cgatgatgct cacttaatca
     3661 atgcggaaat gacagtacgc ttgcaagttg tggacaatca attgcacttt gatgtgacca
     3721 agattgtcaa ccacaatcaa gtcactccag gtcaaaagat tgatgacgaa agaaaactac
     3781 tttcttctat tagtttcctc ggcaatgctt tagtctctgt ttctagtgat caaactggtg
     3841 ctaagtttga tggggcaacc atgtcaaaca atacgcatgt cagcggagat gatcatatcg
     3901 atgtaaccaa tccaatgaag gatttggcta agggttacat gtatggattt gtttctacag
     3961 ataagcttgc tgctggtgtt tggagtaact ctcaaaacag ctatggtggt ggttcgaatg
     4021 actggactcg tttgacagct tataaagaaa cagtcggaaa tgccaactat gtaggaatcc
     4081 acagctctga atggcaatgg gaaaaagctt ataagggcat tgttttccca gaatacacga
     4141 aggaacttcc aagtgctaag gttgttatca ctgaagatgc caatgcagac aagaacgttg
     4201 attggcaaga tggtgccatt gcttatcgta gcattatgaa caatcctcaa ggttgggaaa
     4261 aagttaagga tatcacagct taccgtatcg cgatgaactt tggttctcaa gcacaaaacc
     4321 cattccttat gaccttggat ggtatcaaga aaatcaatct ccatacagat ggtcttgggc
     4381 aaggtgttct ccttaaagga tatggtagcg aaggccatga ctctggtcac ttgaactatg
     4441 ctgatattgg taagcgtatc ggtggtgtcg aagacttcaa gaccctaatt gagaaggcta
     4501 agaaatatgg agctcatcta ggtatccacg ttaacgcttc agaaacttat cctgagtcta
     4561 aatacttcaa tgaaaaaatt ctccgtaaga atccagatgg aagctatagc tatggttgga
     4621 actggctaga tcaaggtatc aacattgatg ctgcctatga cctagctcat ggtcgtttgg
     4681 cacgttggga agatttgaag aaaaaacttg gtgacggtct cgactttatc tatgtggacg
     4741 tttggggtaa tggtcaatca ggtgataacg gtgcctgggc tacccacgtt cttgctaaag
     4801 aaattaacaa acaaggctgg cgctttgcga tcgagtgggg ccatggtggt gagtacgact
     4861 ctaccttcca tcactgggca gctgacttga cctacggtgg ctacaccaat aaaggtatca
     4921 acagtgccat cacccgcttt atccgtaacc accaaaaaga tgcttgggta ggggactaca
     4981 gaagttatgg tggtgcagcc aactatccac tgctaggtgg ctacagcatg aaagactttg
     5041 aaggctggca aggaagaagt gactacaatg gctatgtgac taacctcttt gctcatgacg
     5101 tcatgactaa gtacttccaa cacttcactg taagtaaatg ggaaaatggt acaccggtga
     5161 ctatgaccga taacggtagc acctataaat ggactccaga aatgcgagtg gagttggtag
     5221 atgctgacaa taataaagta gttgtaactc gtaagtcaaa tgatgtcaat agcccacaat
     5281 atcgcgaacg tacagtaacg ctcaacggac gtgtcatcca agatggttca gcttacttga
     5341 ctccttggaa ctgggatgca aatggtaaga aactttctac tgagaaggaa aagatgtact
     5401 acttcaatac gcaggccggt acaacaactt ggacccttcc aagcgattgg gcaaagagca
     5461 aggtttacct ttacaagcta actgaccaag gtaagacaga agagcaagaa ctaactgtaa
     5521 aagatggtaa aattacccta gatcttctag caaatcaacc atacgttctc tatcgttcga
     5581 aacaaaccaa tcctgaaatg tcatggagtg aaggcatgca catctatgac caaggattta
     5641 atagcggtac cttgaaacat tggaccattt caggcgatgc ttctaaggca gaaattgtca
     5701 agtctcaagg ggcaaacgat atgcttcgta ttcaaggaaa caaagaaaaa gttagtctca
     5761 ctcagaaatt aactggcttg aaaccaaata ccaagtatgc cgtttatgtc ggtgtcgata
     5821 accgtagtaa tgccaaggcg atcatcactg taaacactgg tgaaaaagaa gtgactactt
     5881 ataccaataa gtctctcgct ctcaactatg ttaaggccta cgcccacaat acacgtcgtg
     5941 acaatgctac agttgacgat acaagttact tccaaaacat gtacgccttc tttacaactg
     6001 gatcggacgt ctcaaatgtt actctgacat tgagtcgtga agctggtgat gaagcaactt
     6061 actttgatga aattcgtacc tttgaaaaca attcaagcat gtacggagac aagcatgata
     6121 caggtcaagg aaccttcaag caagactttg aaaatgttgc tcagggtatc ttcccatttg
     6181 tagtgggtgg tgtcgaaggt gtcgaagaca accgcactca cttgtctgaa aaacacgatc
     6241 catatacaca acgtggttgg aacggtaaga aagttgatga tgttatcgaa ggaaattggt
     6301 cactcaagac aaatggacta gtgagccgtc gtaacttggt ttaccaaact attccgcaaa
     6361 acttccgttt tgaagcaggt aagacctacc gtgtaacctt tgaatacgaa gcaggttcag
     6421 acaataccta tgcttttgta gtcggtaagg gagaattcca gtcaggtcgt cgtggtactc
     6481 aagcaagcaa cttggaaatg catgaattgc caaatacttg gacagattct aagaaagcca
     6541 agaaggcaac cttcctcgtg acaggtgcag aaacagggga tacttgggta ggtatctact
     6601 caactggaaa tgcaagtaat actcgtggtg attctggtgg aaatgccaac ttccgtggtt
     6661 ataacgactt catgatggat aatcttcaaa tcgaagaaat taccctaaca ggtaatatgt
     6721 tgacagaaaa tgctctgaag aactacttgc caacggttgc catgactaac tacaccaaag
     6781 agtctatgga tgctttgaaa gaggcggtct ttaaccttag tcaggccgat gatgatatca
     6841 gtgtggaaga agcgcgtgca gagattgcca agattgaaac cttgaagaat gctttggttc
     6901 agaagaaaac ggctttggta gcagatgact ttgcaagtct tacagctcct gctcaggctc
     6961 aagaaggtct tgcaaatgcc tttgatggaa acttatctag tctatggcat acatcttgga
     7021 atggtggaga tgtaggcaag cctgcaacca tggtcttgaa agaaccaact gaaatcactg
     7081 gacttcgtta tgttccacgt ggatcaggtt caaatggtaa cttgcgtgat gtgaaacttg
     7141 ttgtgacaga tgagtctggc aaggagcata cctttactgc aactgattgg ccagataaca
     7201 ataagccaaa agacattgat tttggtaaga caattaaggc taagaaaatt gtccttacag
     7261 gtactaagac ttacggagat ggtggcgata aataccaatc tgcagcggaa ctcatcttta
     7321 ctcgtccaca ggtagcagaa acacctcttg acttgtcagg ctatgaagca gctttgacta
     7381 aggctcagaa attaacagac aaagacaatc aagaggaagt agctagcgtt caggcaagca
     7441 tgaaatatgc gacggataac catctcttga cggaaagaat ggtggaatac tttgcagatt
     7501 atctcaacca attaaaagat tctgctacga aaccagatgc tccaactgta gagaaacctg
     7561 agtttaaact tagctcttta gcttccgagc aaggtaagac gccagattat aagcaagaaa
     7621 tagctagacc agaaacacct gaacaaatct tgccagcaac aggtgagagt caatctgaca
     7681 cagccctctt cctagcaggt gttagcctag ccctatctgc tctctttgta gtaaaaacga
     7741 agaaagacta gtatttagta aaacctctta acaagattac ggaagcagtc tctatctttt
     7801 ccaatgaggt ttatagtaca gaaaaagcct gagaagatgt cttctcaggc ttttgttaag
     7861 cacataaata caatagtgct atgaaaaaat cacccagaaa aatctgggtg ataaatgtta
     7921 tggttgtgct gattgaggat tctgattttg ttgatcaggg gttgtatttg attgttgcgt
     7981 attattgtta ggattggtag tcgtactatt atttgtgctt ggagtggttg agctagactg
     8041 tgaagttgaa ctatctgatg atgagcttga actttcagtt gatgggggtt gttgtggagc
     8101 aggtgagctc cacgtagaac gagcaccatt tttaaatacg aattctccat ttctgtagag
     8161 cccctctggt atattccaat cctctggatt gcttccttca gacaggtagg tcatcataga
     8221 gcggtaaact ttggcagcga ccgtaaggcc attgcctaca agtggtgtca gacggttaga
     8281 atagcctgtc catacagcca ttgaatattt acgcgtatag ccagcaaata gttcatcagg
     8341 tgctacaaat tgagaggtct tgatgtggtt ttcaatttcc tcgtctgtat agttagaggt
     8401 tcctgtttta ccagcctgag ggagccaagc aagataggca tttcgtccag ttccataact
     8461 caagactgtt ttcatcatgt cggtcatcat ataggctgtc gtttccttca tggcacgagt
     8521 tccgacatta gagaactctt tttcactccc atcactaaag acgactttat ggatatacat
     8581 tggtttatag taagttccac catttgcaaa ggcagcgtaa gcagcagcca tcttttcact
     8641 acttgctcca tattttttgt ctgattcggt tgtgttactt gaaatggcat ttgagtagtg
     8701 aatacttggg tagtcgattc cgagaccatt taggaaagtc ttggcgcggt tgagtccgac
     8761 cttgtttaga gtttccacgg ctgggacgtt tcgcgattgt tgcagggcgt attgcaaggt
     8821 gatgttgcca aagtagcccc tatcccagtt ataaacagga gtatttgtcc cagggtagtt
     8881 atagggctca tcgtgaacga tagtagcagt tgaatcgtag acaccgtact ccaaggcagg
     8941 agcatagtct gtgatcggtt tcatagttga tccccagtcg cggtttgttt ctactgcttg
     9001 gttaattccg aaggaaacat tacttgactg atggcgtgct cctagctggg caatgacttt
     9061 accgttagaa acatcaacaa tggtagaagc gacttgcaat tcatcgtctg gataggcaac
     9121 gtattcgtct gtattgtaaa tatcccacag atgtttttga gcttcttggt ctacatttgt
     9181 gtagacatcc atcccagttg tgagcaggtt atagcctgtt tcttcttcaa cttgattgat
     9241 gacttccttg aggtaattat ccatgtaagc agggtaatta cttgctgatt tgagactttg
     9301 tagtccatca gtaattggtg tattgactgc tttctcatac tgttcagcag agatgtagcc
     9361 ttgatttttc atttcagata agaccaagtt tcggcggtct tgggctgctt ctggatgtga
     9421 ataggggtca tattggtttg gtgcctgagg cattccagcc agcaaggcta actgaggtaa
     9481 acttaaatta ttgaggtctt taccatagta gttttgagct gctgtctgca ttccatagtt
     9541 cccattagac atgtagacct tatttatata gtaggtcaag atttcttgct tggttgcttt
     9601 ttgttctaac tgaatcgcta accaagcttc ctgagcctta cgagaaatag tctggtcgga
     9661 agtcgaagtt gaaaagtaag tcaacttaat caactgttga gtgagagttg atccaccttg
     9721 gagggaattg ctttgcagat tgcgcaagaa agctcccagg atacggatgg tatcaatccc
     9781 cctgtggtcg aagaagcgat ggtcttcgat agaaacgatt gccttaacca aatctgtggg
     9841 aatatcatta gcttgggcat tgacgcggcg ttcagaaccc aagtcagcaa tgagttgatt
     9901 tttattgtcg tagattttac tagaagttgt tgcaactagt ttactctcgg ataggctagg
     9961 agccttgcta acgtagtaga aaaaaactcc tccgcctaag acaatggctg cgataaccaa
    10021 gcttaagaag ctaatgctca gatacttgat taggcgcaga atcgttggtt tgttcatctt
    10081 gttttaccac ctaataaatg ttctttgata acattgagat aaggaatttg agggaaggca
    10141 ccagccttga tttcatatcc atattctcga atatattcaa gtggcattga tttttgtctc
    10201 ttatcttgat gatagaagcg aatcaaatcg aatgccggca ataagtaggt ttcttgctga
    10261 gaagaaaagt gaagaaggac aaagcagatt ccttgttggg caaggacttg ttccatatgc
    10321 tgaatctgat gtggatgaaa atttttcatc ggaatcgcac gtttttgttt tgtttccttg
    10381 acttcaaagt cgatgtaata tccattataa acgccagaat agtccgtcgt tgaagcttgt
    10441 cgaaaatagg cttcaacaat cttggcacga cttcgttgtg gatagtccac ttgtacgatt
    10501 tgaataggag ttggtttctt atgtataaca gccaagccct gagacaaata gtagtcgttg
    10561 gtagcattga tcatcttttc aaaagacatt cctcgatttg cgaaattttt gggttgagaa
    10621 agagatgttt gtcttttttg tgatgaaact ttatgtggat agttgaccat aattctcctt
    10681 attggtacaa taacatcact ttattatacc ataatttgca cagaaagggt taaaaatggc
    10741 tacagctttg gttttaggct attctgcttt tgatttgggt ttattttctg ataaggatcc
    10801 tcgtcttaaa ttgattaaaa aagcgatacg taaagattta gaggctatgg cagcagatgg
    10861 ggtgtcttgg cttgtgttta cagggagttt gggttttgaa tattgggttt tagaggttgc
    10921 tcaggagatg aaaaccgaat acggtttcca gttggccacc atttttgctt ttgaaaccca
    10981 tggggaaaat tggaatgaag gcaatcagat gaaactgagt cgctttaagc aggtagactt
    11041 tgtcaaatat gcttatcctc gctatgaaca caaggggcag ttaagagatt accagcagtt
    11101 tttgctggaa aacacgacta gttcctatct tttttatgat gaagaaaatg aaacaaaact
    11161 agcttatttt taccaaaaga tgaaaaatca agaggactat tttataaaga gattaacatt
    11221 tgatgaatta aatgaacttg ctgaaaattt ttccgaaaat tgaagctttg accttgattt
    11281 ttgtttgcct ttttttatat aataatacta gcaagcgaga atggagagag acatggcaag
    11341 tattattttt tcagcgaaag atatttttga acaagagttt ggacgtgaag tccgtggcta
    11401 taataaagta gaagttgacg agtttttaga cgatgtcatc aaggactatg aaacctatgc
    11461 tgccttggtc aagtcacttc gtcaggaaat tgcggatttg aaggaagaat taactcgtaa
    11521 accgaaacct tcaccagttc aagcagaacc ccttgaagcg gcaattacaa gttctatgac
    11581 gaattttgat attttgaaac gcctgaatag attggaaaaa gaagtttttg gtaaacaaat
    11641 tttagataac tcagattttt aagtagttat ttgagatgtg caatttttgg ataatcgcgt
    11701 gaggagaatt gcttctcatg aggaaagtcc atgctagcac aggctgtgat gcctgtagtg
    11761 tttgtgctag gcgaaaccat aagcctaggg acgagaaatc gttacggcag ttgaaatggc
    11821 taagtccttg gataggccag agtaggcttg aaagtgccac agtgacggag tctttctgga
    11881 aacagagaga gtggaacgcg gtaaacccct caagctagca acccaaattt tggtcggggc
    11941 atggagtacg cggaaacgaa cgtagtattc tgactgctat cagctagagc tgttagtggt
    12001 agacagatga ttatcgaagg aagtggtcct agtcacttct ggaacaaaac atggcttata
    12061 gaaaattgca tataggttgg ggctgagaaa ttttctcaac ctcatttttt aaagtggaca
    12121 tatagaaagg tcttgcaaga ctgtaacatg aaaaaagaat ttaatttaat tgcaactgtg
    12181 gcagcagggc ttgaggctgt cgttggtcgt gaagtgcgag agttgggcta cgattgtcag
    12241 gttgaaaatg gacgtgttcg ttttcaagga gacgtgagag ctattatcga aaccaacctt
    12301 tggcttcggg cagcagatcg tatcaaaatt atcgtaggaa cgttcccagc taagactttt
    12361 gaagagctat ttcagggagt tttcgcttta gattgggaaa attatttacc acttggagct
    12421 cggttcccga tttcaaaagc taaatgtgtt aagtccaaac ttcacaatga gcccagtgtt
    12481 caggctattt ctaagaaagc tgttgtcaag aaattgcaga aacactatgc tcgcccagaa
    12541 ggggttcctc tgatggagaa tggcccagag tttaagattg aggtctctat tctcaaagat
    12601 gtggcaactg tcatgattga tacgaccggg tctagcctct ttaaacgtgg ttatcgtacc
    12661 gaaaaaggtg gcgctcctat caaggaaaat atggcagcag ccattttaca actttctaac
    12721 tggtatccag acaagccttt gattgatccg acctgtggtt cggggacttt ctgtattgag
    12781 gcagttatga ttgctagaaa gatggcgcca ggtcttcgtc gctcttttgc atttgaggaa
    12841 tggaactgga tcagcgatcg cttgattcaa gaagtgcgca cagaagcggc taaaaaagta
    12901 gaacgtgagc ttgagttgga tatcatgggc tgtgatattg atgctcgcat ggtggaaatt
    12961 gctaaggcca atgctcaggc agctggtgtt gcaggagaca ttacttttaa gcagatgcgc
    13021 gtgcaggatt tacgttccga taaaatcaat ggagtaatca tttccaatcc gccttatggt
    13081 gaacgtttgt cagatgatgc aggggtgacc aagctctatg ctgagatggg gcaagtattt
    13141 gcaccgctga aaacttggag caaatttatc ctgactagtg atgaagcttt tgaaagcaag
    13201 tatggtagcc aagcagataa gaagcgtaag ttatacaacg gaaccttgaa agtggatcta
    13261 tatcaatatt ttggtcagcg tgtcaaacgg caagaggtaa aatagaaagg gatactcatg
    13321 agtaaaaaaa gacgaaatcg tcataaaaaa gaaggtcaag aaccgcaatt tgattttgat
    13381 gaagcaaaag agctaacagt tggtcaagct attcgtaaaa atgaagaagt ggaagcagga
    13441 gtcttgcctg aggattccat tttggacaag tatgttaagc aacacagaga tgaaattgag
    13501 gcggataagt ttgcgactcg tcaatacaaa aaagaggagt tcgttgaaac tcagagtctg
    13561 gatgatttaa ttcaagagat gcgtgaggct gtagagaagt cagaagcttc ttcggaggaa
    13621 gttccatctt ctgaagacat cttactaccc ttgcctctgg acgatgagga gcaaggcttg
    13681 gatcctctat tgctagatga tgaaaatcca acagaaatga ctgaagaagt ggaagaggag
    13741 caaaaccttt ctcgtctgga tcaagaggac tcagaaaaga aaagtaaaaa aggctttatt
    13801 ttgaccgttt tggcgcttgt atcagtaatt atttgtgtca gtgcttatta tgtctaccgt
    13861 caagtggctc gttcgaccaa ggaaattgaa acttctcaat caactacagc caatcaatca
    13921 gatgtggatg attttaatac actttatgac gccttttaca cagatagcaa taaaacggct
    13981 ttgaaaaata gccagtttga taaactgagt caactcaaaa ccttgcttga taaactggaa
    14041 ggtagtcgtg aacatacgct tgccaaatct aaatatgata gtctagcaac gcaaatcaag
    14101 gctattcaag atgtcaatgc acaatttgaa aaaccagcta ttgtggatgg tgtgttggat
    14161 accaatgcca aagccaaatc ggatgctaaa tttacggata ttaaaactgg aaatacggag
    14221 cttgataaag tgctagataa ggctatcagt cttggtaaga gccagcaaac aagtacttct
    14281 agctcaagtt caagtcaaac tagcagctca agctctagtc aagcaagttc aaatacgact
    14341 agtgagccaa aaccaagtag ttcaaatgag actagaagta gtcgcagtga agtcaatatg
    14401 ggtctctcga gtgcaggggt tgctgttcaa agaagtgcca gtcgtgttgc ctataatcag
    14461 tctgctattg atgatagtaa taactctgcc tgggattttg cggatggtgt cttggaacaa
    14521 attctagcga cttcacgttc acgtggctat atcactggag accaatatat ccttgaacgt
    14581 gtcaatatcg ttaacggcaa tggttattac aacctctata agccagatgg aacctatctc
    14641 tttaccctta actgtaagac aggctacttt gtcggaaatg gcgctggtca tgcggatgac
    14701 ttggactact aagcagtcgt tacaaaattc tttcttttca aaagtaaaaa tgataaaata
    14761 aaacaaatga aacaagagga gtgtcaaatg acaaaagcta actttggtgt cgtaggtatg
    14821 gccgtaatgg gtcgtaacct tgcccttaat attgaatcac gtggttacac agttgctatc
    14881 tacaaccgta gtaaagaaaa aacggaagat gtgattgctt gccatcctga aaagaacttt
    14941 gtaccaagct atgacgttga aagttttgta aactcaatcg aaaaacctcg tcgtatcatg
    15001 ctgatggttc aagctggacc tggtacagat gctactatcc aagcccttct tccacacctt
    15061 gacaagggtg atatcttgat tgacggtgga aatactttct acaaagatac catccgtcgt
    15121 aatgaagaat tggcaaactc aggtatcaac tttatcggta ctggagtttc tggtggtgaa
    15181 aaaggtgccc ttgaaggtcc ttctatcatg cctggtggac aaaaagaggc ctacgaattg
    15241 gttgcggatg ttcttgaaga aatctcagct aaagcaccag aagatggcaa gccatgtgtg
    15301 acttacatcg gtcctgatgg agctggtcac tatgtgaaaa tggttcacaa tggtattgag
    15361 tacggtgata tgcaattgat cgcagaaagc tatgacttga tgcaacactt gctaggcctt
    15421 tctgcagagg atatggctga aatctttact gagtggaaca agggtgaatt agacagctac
    15481 ttgatcgaaa tcacagctga tatcttgagc cgtaaagacg atgaaggcca agatggacca
    15541 atcgtagact acatccttga tgctgcaggt aacaagggaa ctggtaaatg gacgagccaa
    15601 tcatctcttg accttggtgt accattgtca ctgattactg agtcagtgtt tgcacgctac
    15661 atttcaactt acaaggaaga acgtgtacat gctagcaagg tgcttccaaa accagctgcc
    15721 ttcaactttg aaggagacaa ggctgaattg attgaaaaaa tccgtcaagc cctttacttc
    15781 tcaaaaatca tttcatacgc acaaggattt gctcaattgc gtgtagcctc taaagaaaac
    15841 aactggaact tgccatttgc agatatcgca tctatctggc gtgatggctg tatcatccgt
    15901 tctcgtttct tgcaaaagat tacagatgct tacaaccgcg atgcagatct tgccaacctt
    15961 cttttggacg agtacttctt ggatgttact gctaagtatc aacaagcagt gcgtgatatc
    16021 gtagctcttg cggttcaagc tggtgtgcca gtgccaactt tctcagcagc tattacttac
    16081 tttgatagct accgttcagc tgaccttcca gctaacttga tccaagcaca acgtgactac
    16141 tttggtgctc acacttacca acgtaaagac aaagaaggaa ccttccacta ctcttggtat
    16201 gacgaaaaat aagtaggtca gccatgggga aacggatttt attacttgag aaagaacgaa
    16261 atctagctca ttttttaagt ttggaactcc agaaagagca gtatcgggtt gatctggtag
    16321 aggaggggca aaaagccctc tccatggctc ttcagacaga ctatgatttg atgttattga
    16381 acgttaatct gggagatatg atggctcagg attttgcaga aaaattgagt cgaactaaac
    16441 ctgcctcagt catcatgatt ttagatcatt gggaagactt gcaagaagag ctggaagttg
    16501 ttcagcgttt tgcagtttca tacatttata agccagtcct tatcgaaaat ctggtagcgc
    16561 gtatttcggc gatcttccga ggtcgggact tcattgatca acactgcagt ctgatgaaag
    16621 ttccaaggac ctaccgcaat cttaggatag atgttgaaca tcacacggtt tatcgtggtg
    16681 aagagatgat tgctctgacc cgccgtgagt atgacctttt ggcgacactt atgggaagca
    16741 agaaagtatt gactcgtgag caattgttgg aaagtgtttg gaagtatgaa agtgcgaccg
    16801 agacaaatat cgtagatgtc tatatccgct atctacggag caagcttgat gttaaaggcc
    16861 aaaaaagcta cattaaaacc gtgcgtggtg ttggatatac catgcaagaa tagataagca
    16921 gttgcagttg tgtaactgct tttttgagga gtttttatat attgacatgc agtcgggtct
    16981 ttgctacaat cgttttagga ggatatatag atgaaacttt tgaaaaaaat gatgcaagtt
    17041 ctactagcag tctttttctt tggtttgcta gctacaaata cggtatttgc gaataccaca
    17101 ggtggccgat ttgttgataa ggataataga aaatattatg taaaagatga tcataaagca
    17161 atctattggc ataaaataga cggtaaaact tactattttg gtgatattgg agagatggtt
    17221 gtcggttggc aatacttaga aattcctgga acaggttatc gtgataattt attcgataac
    17281 caaccagtta atgaaattgg ccttcaggag aagtggtact attttggaca agatggtgct
    17341 ttgctagaac aaacagataa acaagtacta gaggcaaaaa cgtctgaaaa tacaggaaaa
    17401 gtatacggtg aacaatatcc tctatctgct gaaaagagaa cttattattt tgataataat
    17461 tatgctgtaa agacaggctg gatttatgaa gacggcaatt ggtattattt aaataagcta
    17521 ggaaattttg gcgatgattc ttacaatcca ctaccaatta gtgaagttgc taagggttgg
    17581 actcaagatt ttcatgttac tattgacatt gatagaagca aacctgctcc atggtactac
    17641 ctagacccag aaactggcat tatgcgaaca ggatggcaat atctaggtaa taactggtac
    17701 tacctccgtt catcaggagc aatggccact ggctggtatc aggaaggtac cacttggtat
    17761 tatttagacc agccaaatgg cgatatgaaa acaggttggc aaaaccttgg gaacaaatgg
    17821 tactatctcc gttcatcagg agctatggca actggttggt atcaagatgg ttcaacttgg
    17881 tactacctaa atgcaggtaa tggagacatg aagacaggtt ggttccaggt caatggcaac
    17941 tggtactatg cttatagctc aggtgctttg gcagtgaata cgaccgtaga tggctattct
    18001 gtcaactata atggcgaatg ggttcggtaa tgacagggcg cttataatta tattagaaca
    18061 ctcgcttaat caaagaagtg actttgttgt acttgacctg acgattgggg agattaaaag
    18121 catgtgaaat ctacacatgc tttttcgtta gttatgagtg ttgaacttga ctaaccattg
    18181 acaaaagata agagcaatta aaataagata caaaaatatc aatgctaact gcaccgaaac
    18241 gcccgatgct atggataggg ctaataggga gagcagggac ggggcgagaa tgtccactgt
    18301 gctcagagca gagcccaccg tccccatctt gtcactgggg atataggcaa agacagctgc
    18361 ttgtaggcga gggctgagaa tgccgataat cgtagaactg atgaaactgg tcatgaaaat
    18421 tacgatatag gcttgacaaa ggatactagt tattagagcc aatagggaaa tctcacagaa
    18481 aaccaagagg tgcgtgaaac ggatattttt aaatagatta ctgctggtca tattgccaag
    18541 gatagctcca caagacatga tgatggagag cagggcgagg agttgcccaa tgctcagttg
    18601 tgctagtgtc tgttggatga agcggagggc aatcagccga ggggacacat ccaagatggc
    18661 aatcatactg gtcgtcagaa acagtagtat gacggtatct tttaacttca gtagcacagc
    18721 cagcgactgt ttaagatgtt gaaaatattt cttaaaactc agtgctgtat gtgacatttc
    18781 aatccttttt tcaacctcat acaaggtatg tcgaataaca tacaggccca aaaaggcaat
    18841 gacaaaagtc agagtgttga taagggaaat agtttgaata cttataacat tgataaggaa
    18901 tgcgccagcc agattggcga caatgcggac aaccctcatc agagactgcc tgaaccccat
    18961 ggcatcatgc aggtcgtcct taattacact gatgtagagg gcgttcatca tgtaggcaga
    19021 caggtagctc aaggtgtcag agatgaggtt gatgatgaca atcataatga ctgaaactaa
    19081 tgaaaagggc gacaagacga gaaatactgt caaaatagcg tagagcagga ttttgatttt
    19141 ggcaatacag agtgcgtgtt tgactctatt ttcttgaaaa tctcctagaa tcccgagaaa
    19201 gagttgcgat agtaggggaa ccatctctga aatggaaatc agtaaaatcg ctagcggagc
    19261 gaaattgtac tgagccacat aattgataat ggcgaggtag aaaatactgt cgccgaatga
    19321 tgaaaaacag ctgtttagca gcaactgtct atatatgttg tttgtccaaa ataatttcat
    19381 acatttctcc ttatgtctgc acatcgaatg ggaatttatt atttaataga caccaatata
    19441 cccccatgct tcctattccg aagtcaaaca aatctgcttt accactatct ccttgaaaca
    19501 tcagtaaacc gtgatcatct cgttcagaac atgctaaaat tacctgttgg attttttcat
    19561 cagtaatttg ttttgattgt agacagtggt ttgtagtaag ctagttattc cgtggcaata
    19621 tcctgtcatc atttttagat gatggttaaa aacaaattct tgatatttac taataatatc
    19681 tttgtttccg tcacaatcgt acatacaaag atataagatt attccggaaa ttcctttgca
    19741 ccaagaaagt tgtaaatttc ctaaattttc agtattagaa gtaacttttt ctaataattt
    19801 ttttaattca gtatggaatg tatggagatc attatagaac atagaaggtt ctaagacttt
    19861 agaataggca aataaagcat atgcaattcc acaatatcca tgagcaaagc tatagtctaa
    19921 aatgctttct ttggctgtat ctctttgtag gaaataatga taaatttccc catatactat
    19981 tgtggatgaa agttttaaga gtattgtcat tggtaacttg atagtatttt attaatgata
    20041 ataggacacc agattttccc aatgcaaagt ctatttcctc tagagtatca taattctcta
    20101 ttaatttctt agcggtgacg tttgctaatt gtagatagta ttgattttta ctgatagaaa
    20161 ataaatgtag gagtaactat agatagcctg caccaccaaa tagcagtgag tattgatatt
    20221 catatgtgtg tgacgttcta attgtcactg ccttcttgat gatagagagt attttagaat
    20281 ccagttctgg gtggtacaat ttatttagag gaaacagtag tccagctatt ccgtgttgga
    20341 atgataaatt acttacgaaa tttccaaatt ctgttgaaga agtgatcctt ccttcagaat
    20401 ttacagtttt atctagtaaa aatcgtagaa cactattaca ttctgttttg taatcatatt
    20461 tatgttcctc tattttttta attttgacta aattatttgt ttgacttaaa tttagtagac
    20521 attgtaacca aaatagttgc tcatctgtga gctgaccttg agtatgtgat agttctagta
    20581 attgaatagg atcctttagt tagattcaat caatctataa cacaacaaca taataatact
    20641 tttaggataa cttgtcaaat a
//
LOCUS       DAVBOH010000037        20110 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOH010000037 DAVBOH010000000
VERSION     DAVBOH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20110
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.037"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ873_001515"
     CDS             638..952
                     /locus_tag="VQ873_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3107756.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ873_001516"
     CDS             968..1354
                     /locus_tag="VQ873_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3107757.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ873_001517"
     CDS             1383..2768
                     /locus_tag="VQ873_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3107758.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ873_001518"
     CDS             2771..2923
                     /locus_tag="VQ873_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3107759.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ873_001519"
     CDS             2946..4151
                     /locus_tag="VQ873_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3107760.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ873_001520"
     CDS             4194..4415
                     /locus_tag="VQ873_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107761.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ873_001521"
     CDS             4532..5029
                     /locus_tag="VQ873_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3107762.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ873_001522"
     CDS             5004..5510
                     /locus_tag="VQ873_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3107763.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ873_001523"
     CDS             5494..7941
                     /locus_tag="VQ873_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3107764.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10121
                     /locus_tag="VQ873_001524"
     CDS             7944..10121
                     /locus_tag="VQ873_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3107765.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10118..11119
                     /locus_tag="VQ873_001525"
     CDS             10118..11119
                     /locus_tag="VQ873_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3107766.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11116..12051
                     /locus_tag="VQ873_001526"
     CDS             11116..12051
                     /locus_tag="VQ873_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3107767.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12296..12412
                     /locus_tag="VQ873_001527"
     CDS             12296..12412
                     /locus_tag="VQ873_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3107768.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ873_001528"
     CDS             12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ873_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3107769.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14466..14633
                     /locus_tag="VQ873_001529"
     CDS             14466..14633
                     /locus_tag="VQ873_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3107770.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14693..15046)
                     /locus_tag="VQ873_001530"
     CDS             complement(14693..15046)
                     /locus_tag="VQ873_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3107771.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15551..15973
                     /locus_tag="VQ873_001531"
     CDS             15551..15973
                     /locus_tag="VQ873_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3107772.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15970..16200
                     /locus_tag="VQ873_001532"
     CDS             15970..16200
                     /locus_tag="VQ873_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3107773.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16661..16864
                     /locus_tag="VQ873_001533"
     CDS             16661..16864
                     /locus_tag="VQ873_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3107774.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16946..18163
                     /locus_tag="VQ873_001534"
     CDS             16946..18163
                     /locus_tag="VQ873_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3107775.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18325..18927)
                     /locus_tag="VQ873_001535"
     CDS             complement(18325..18927)
                     /locus_tag="VQ873_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107776.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18930..19163)
                     /locus_tag="VQ873_001536"
     CDS             complement(18930..19163)
                     /locus_tag="VQ873_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3107777.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19176..19556)
                     /locus_tag="VQ873_001537"
     CDS             complement(19176..19556)
                     /locus_tag="VQ873_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107778.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19549..19998)
                     /locus_tag="VQ873_001538"
     CDS             complement(19549..19998)
                     /locus_tag="VQ873_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107779.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19982..>20110)
                     /locus_tag="VQ873_001539"
     CDS             complement(19982..>20110)
                     /locus_tag="VQ873_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3107780.1"
                     /translation="AARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESAK"
BASE COUNT         6584 a         3640 c         4064 g         5822 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
     8881 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
     8941 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
     9001 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
     9061 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
     9121 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
     9181 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
     9241 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
     9301 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
     9361 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
     9421 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
     9481 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
     9541 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
     9601 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
     9661 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
     9721 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
     9781 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
     9841 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
     9901 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
     9961 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    10021 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    10081 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    10141 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    10201 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    10261 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    10321 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    10381 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    10441 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    10501 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    10561 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    10621 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    10681 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    10741 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    10801 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    10861 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    10921 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    10981 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    11041 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    11101 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    11161 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    11221 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    11281 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    11341 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    11401 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    11461 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    11521 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    11581 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    11641 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    11701 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    11761 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    11821 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    11881 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    11941 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    12001 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    12061 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    12121 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    12181 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
    12241 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
    12301 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
    12361 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
    12421 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
    12481 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
    12541 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
    12601 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
    12661 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
    12721 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
    12781 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
    12841 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
    12901 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
    12961 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
    13021 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
    13081 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
    13141 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
    13201 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
    13261 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
    13321 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
    13381 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
    13441 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
    13501 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
    13561 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
    13621 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
    13681 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
    13741 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
    13801 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
    13861 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
    13921 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
    13981 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
    14041 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
    14101 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
    14161 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
    14221 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
    14281 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
    14341 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
    14401 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
    14461 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
    14521 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
    14581 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
    14641 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
    14701 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
    14761 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
    14821 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    14881 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    14941 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    15001 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    15061 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    15121 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    15181 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    15241 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    15301 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    15361 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    15421 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    15481 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    15541 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    15601 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    15661 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    15721 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    15781 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    15841 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    15901 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    15961 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    16021 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    16081 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    16141 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    16201 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    16261 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    16321 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    16381 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    16441 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    16501 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    16561 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    16621 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    16681 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    16741 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    16801 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    16861 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    16921 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    16981 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    17041 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    17101 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    17161 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    17221 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    17281 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    17341 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    17401 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    17461 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    17521 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    17581 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    17641 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    17701 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    17761 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    17821 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    17881 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    17941 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    18001 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    18061 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    18121 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    18181 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    18241 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    18301 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
    18361 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
    18421 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
    18481 atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
    18541 caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat tgattaagaa
    18601 caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg cttgatttgt
    18661 gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc taacgaatcc
    18721 aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt ttcgttgacc
    18781 atacatccat aaaaaagaaa tgagcgacgc tccatagata atctgtagta tagttaactc
    18841 accgatacaa agaaatttca gtaagtataa ggataccaat aggacattta cttgttggaa
    18901 tatataaact ggaattattc ttttcatagt tacctccgaa ataaatcttc ataatctaaa
    18961 tctaatacct gcacaatcct ctctacccat ggactttgag gcattcgttg ttccatcttg
    19021 tagtgacgaa tcttttgata caaacgattc aattcacttg gatagtgaaa ctctcccgca
    19081 aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat aatggacaag
    19141 ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata atgtgtttgt
    19201 gccatgtaaa tcaattgttt cgtatctctt ggtaataaag ccctagcttc ctccaaattt
    19261 agatttggat aaactcgctt atttgaaacc gcaagaggaa gtctgatggt tagttcagga
    19321 ttttttaata tcatttcaat gaaatccgtt agtcttaaat tgtcacggtt cttaaatcgt
    19381 aataaattag gagataaaaa ctcaaaacaa tctgaagaat agctcatcat ctcaattaat
    19441 ttatcccttg tcatttcaga aatcgaatga caggatacct caatgccata gttttggaag
    19501 aattctaaaa gaagttgatt tctatggtta tttttactta gatagagatc aatcatgtga
    19561 gacctcccaa agattcggtt ccatttgata ttctgagacg attaaggaat ctaataaatt
    19621 ggagaagtta attgatttct tgtcttcatc ataagctttt acagttactt gggttgtaag
    19681 tattccctct tttccctcgg ctcgatagcc ttgcccatat aaaacaaaaa caagattatg
    19741 attatcatct ataaaggcat cagctccgtt ctttatatcc tgactttcaa ggaattccat
    19801 aatgttttga agataggatt cgtaaaatag ggggtaattg tgttttttat ggtaataatc
    19861 taaaaatgtc acctcaaact cacatggata attgggcatc aaaaatattt gttcatccaa
    19921 ctgcatcatt tctgcatcat gtaattctgt ttctaattca tcacaatata gtattgactc
    19981 tttatttagc gctttcatct ttttcctcta tttcttttaa tttttttgcg attgcggcaa
    20041 tcacaggaac agttacacta ttaccagctt gtttatagag ctgactatta ctagagactt
    20101 ttctagcagc
//
LOCUS       DAVBOH010000038        18498 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOH010000038 DAVBOH010000000
VERSION     DAVBOH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.038"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..353)
                     /locus_tag="VQ873_001540"
                     /pseudo
     CDS             complement(1..353)
                     /locus_tag="VQ873_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(429..863)
                     /locus_tag="VQ873_001541"
     CDS             complement(429..863)
                     /locus_tag="VQ873_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107781.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(939..1789)
                     /gene="rfbD"
                     /locus_tag="VQ873_001542"
                     /pseudo
     CDS             complement(939..1789)
                     /gene="rfbD"
                     /locus_tag="VQ873_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1855..2904)
                     /gene="rfbB"
                     /locus_tag="VQ873_001543"
     CDS             complement(1855..2904)
                     /gene="rfbB"
                     /locus_tag="VQ873_001543"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3107782.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2914..3510)
                     /locus_tag="VQ873_001544"
     CDS             complement(2914..3510)
                     /locus_tag="VQ873_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3107783.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3511..4368)
                     /gene="rfbA"
                     /locus_tag="VQ873_001545"
     CDS             complement(3511..4368)
                     /gene="rfbA"
                     /locus_tag="VQ873_001545"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3107784.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
     gene            4582..5888
                     /locus_tag="VQ873_001546"
                     /pseudo
     CDS             4582..5888
                     /locus_tag="VQ873_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6176..6358)
                     /locus_tag="VQ873_001547"
     CDS             complement(6176..6358)
                     /locus_tag="VQ873_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107785.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(6574..7806)
                     /locus_tag="VQ873_001548"
     CDS             complement(6574..7806)
                     /locus_tag="VQ873_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3107786.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(7835..8905)
                     /gene="gla"
                     /locus_tag="VQ873_001549"
     CDS             complement(7835..8905)
                     /gene="gla"
                     /locus_tag="VQ873_001549"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3107787.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(8973..10142)
                     /locus_tag="VQ873_001550"
     CDS             complement(8973..10142)
                     /locus_tag="VQ873_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3107788.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(10328..11632)
                     /locus_tag="VQ873_001551"
     CDS             complement(10328..11632)
                     /locus_tag="VQ873_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3107789.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNSFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(11749..12903)
                     /locus_tag="VQ873_001552"
     CDS             complement(11749..12903)
                     /locus_tag="VQ873_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3107790.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(12900..13451)
                     /locus_tag="VQ873_001553"
     CDS             complement(12900..13451)
                     /locus_tag="VQ873_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3107791.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(13444..14580)
                     /locus_tag="VQ873_001554"
     CDS             complement(13444..14580)
                     /locus_tag="VQ873_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3107792.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(14721..15386)
                     /gene="cpsD"
                     /locus_tag="VQ873_001555"
     CDS             complement(14721..15386)
                     /gene="cpsD"
                     /locus_tag="VQ873_001555"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3107793.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(15396..16088)
                     /gene="cpsC"
                     /locus_tag="VQ873_001556"
     CDS             complement(15396..16088)
                     /gene="cpsC"
                     /locus_tag="VQ873_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3107794.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(16097..16828)
                     /locus_tag="VQ873_001557"
     CDS             complement(16097..16828)
                     /locus_tag="VQ873_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3107795.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(16830..18275)
                     /locus_tag="VQ873_001558"
     CDS             complement(16830..18275)
                     /locus_tag="VQ873_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3107796.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         5958 a         3779 c         2704 g         6057 t
ORIGIN      
        1 ccgtctttca aaatagtctt aaaggtttct tcatacttga ggctgtattc aattgccctt
       61 cctagttttg aacctgctaa aactgactga cgccggcacc aagcaaagaa gtcttccatt
      121 aggggctgga gatgttcttg acgtttctgt agtcgttcat cagctggcaa agcctcccag
      181 tctctttcca aggaaaataa ctgatcacaa taagctaaac ctttagctcc taaggatgat
      241 ttatccgttt gcttgggggg cgcttcaaaa aacttccttc tcacatgtgc ccaacatcca
      301 acaagttcag cttcttccag ttgacgataa gcttctagcg gttcgcagtt taccaagctt
      361 agcgtcgcct tgctcctaaa ccttggactg ctatcgcata ggcagaacta gaggactaaa
      421 gtcctaagtt actgccgcaa catatcacaa tgcacatagc cagaataatc tcctaggaat
      481 tcttgtacta ctaaaccact ccgacgctga tcatggtggt acagcgtgat tgcttgattc
      541 tcagctttcc cagacaaaaa agtccaatag taggtcagat ggctatcact ctctagaacc
      601 cgataagagg tttcatccgc atgaagaaga ggttgttcta acaacttttc tcgtaaaagg
      661 ttataaaggg actctaaata gtattgactt gccttgatat gccaattaga gatttcctta
      721 cgtgtgattg gtaaacccat cctagcccaa tcttcttctt ggcgataatt gggtaccttc
      781 agattaaact tctgatggat ggtgtgagcg ataatagaaa ctgagccaaa gctatgcacc
      841 aaagagacca gcaccaacaa caagataatt gtacatctta agctcctttg gagttcatta
      901 tctgcctctt ttattagact agaaaatcat tctactactt atctcacttc ttgtttgtaa
      961 aattcttgca atgcatcttg ccaagttgga ataacaaatc cagtagcttt ggctttggcc
     1021 aggctcatcg ttgagtttag cggacgttga gctttggctg gaaattgact ggatctactg
     1081 gcttgacttc gacatctgta tctttcaaaa tttcaactgc aaaatcatac catgttgtgt
     1141 cttctgtcgc atcatttgac aaatgataat aaccaaattc cttacgattt tcagctaggt
     1201 agatcatgaa ttcagccaag gtacgagtcc aagtcggacg accgtactgg tcatttacaa
     1261 ctgttaaagt cttatgagtt ttcgcaagat tttgcatggt aaaaacgaag tttttgccat
     1321 aatttccaaa tacccaggca gtacggataa tatagaaatt agacacatgc ttctcaacta
     1381 actcttcccc catacgctta gtgcgtccat attctgtctg tggatctggt cggtcatcaa
     1441 cttcccactc ttgtccaact ggtttcttac cgtcaaagac ctagtccgta gaaatataaa
     1501 ctagagttgc accatgcttt tcagatgctt ttgcgacatt ttttgtcccc atcacattga
     1561 tggcgaagtc caactctttt ccttcatcct ctgctgcatc aacagcggtg taggctgcac
     1621 aatggtagac taaagtcggt ttcacctctt caaaaacttt ctcaaccatt tcttcattgg
     1681 taatgtccat ctcagccaca tctactgcca cgtattcttc attacgttca tccaataaat
     1741 agcgaagttc cgttcctaat tggccatttg cccctgtaat taaaatcatc tctagacctt
     1801 tctaatatgt aactcttccc aatatagcaa taaaaagcag cgatttcctg ctttttatac
     1861 tgtaataatc tcctgagtct tagcataatt ggcttcaaca gcttcttttt ctgctttcca
     1921 ccattcttgg ttatctgtat accacttgat tgttgccttg agcccagctt caaagttggt
     1981 aaattcaggt ttccacccca actcatcacg gagcttgctg gcatcaatcg catagcgaag
     2041 gtcatgtcct gcacggtcag tcacatgatc ataggcatcc gtagcttgtc ccatttcctt
     2101 aaggataagt tccaaaactt ccttattgtt cttctcacca tcagccccaa tcaagtaggt
     2161 ttcaccgatt tgcccttttg tcaagattgt ccaaactcct gaagaatggt cattggtatg
     2221 aatccagtca cgaacgttct taccttcacc gtaaagtttt ggcttaattc cacttaggat
     2281 gttagtaatc tgacgtggga tgaatttttc gatatgttga taaggaccgt agttatttga
     2341 acagttggaa atcgttgcct tgactccaaa agaacgcacc caggctttga caatcaagtc
     2401 tgatgcggcc ttggttgatg agtacggaga gcttgggttg tattttgttt cagcagtaaa
     2461 tttctcacct ggtccttcac catgacctgg caaatcttct cgtaaaggga gatccccata
     2521 aacttcatct gtcgatacat ggtggaagcg aatatcatac ttacgagcag cttctaaaag
     2581 agtatagatt ccaatgaagt tagtatgaat aaatggcgat ggatcattga gcgaattatc
     2641 attgtggctt tccgctgcat aatgaacgat agcatctgct tgagcaacca acttgtctac
     2701 caactccgca tcagcaatgt caccaacaac taactcaaca cgattgccta aaatttcctc
     2761 aatattcgcg cggtttccag cataagtcaa cttatctagg actgtcacgt gaacatctgg
     2821 aaagttctcg taaacataat ggacaaagtt agaaccgata aagccagctc cacctgtcac
     2881 gataatattt ttgtattcag tcatattctt tccttattcc aaatcttctt ttttcaaagg
     2941 cttcacgtcc ttaagtaggg gatgatgttt gtctgcttca gatacgtctg cttcttccag
     3001 attttcccat tcaataccaa ggcttggatc agcgtagttc acaaaggcat acttgggttt
     3061 gagttcaaga gcccagtaat cattgaccag atagctatat gacactgtat ctgataaaac
     3121 ttggaagcca ttagctacgc ctcgaggaac aaagattccc ttgcttgcat caattactgt
     3181 ctgataggta ttcccaaagg tttcaccctc gcgtagatca acccaagaac ccagaacttt
     3241 ccctccatct gctacagaga tgtacttatc ccaaggctct gcgtggaggc ctcgaaggac
     3301 atttttacgt gagaaggata cattgttttg caattttcct tctgcaaaga aagactctgg
     3361 aaatccaagt ggaagcactt tttccttttg gaaattttct ttaaaccagc cacgattatc
     3421 tccatgaacg gggatatcaa actccaacat gcctggaata gcttcaacct tgcgtgccgc
     3481 aagcgtctta ccgaaaaaat tatctgtcat ctatgcttct ccaatcaaac ggagcagata
     3541 ctgtccgtat tcatttttct taagtggttg ggctaaggcc aatacatctt ctcgactgat
     3601 atagcccata cggtaagcaa tttcttctaa gtttgctacc tgaacatttt gcatccgttg
     3661 cactgtttcg atgtactgtg aagcctctag taaactttca tgagttccag tattcagcca
     3721 agcaaagcca cgtcccataa gctcaacaga caaatcacca cgatctaggt aaaccttgtt
     3781 tacatctgta atttccagtt caccacgagg gcttggttta atactcttgg caatttcgac
     3841 aacatcgtta tcatagaaat acagtcctgt cactgcatag ttggagcgag gatactccgg
     3901 tttttcttct atggaaatag cattcatgtc tgtatcaaac tcaaccacac caaaacgctc
     3961 tggatccttc acttggtagc caaaaacagt cgcacctttc tctttcttgg ctgctttttg
     4021 aagcattgtg ctcagaccag gaccatggta gatattgtcg cctaaaatca aggcaacgct
     4081 atcgtcagaa ataaactctt ccccaattgc caaaccatct gtacttggtt gctctgcata
     4141 agaaagtttg atcccaaact cagatccgtc ttgaagaagc tcttgaaatc gatgtaaatc
     4201 ctgtggagtg gaaataatca aaatatccct aatcccagcc aacatcaatg ttgaaagtgg
     4261 gtagtaaatc atcggtttat cataaaccgg cataagttgt tttgacgcag cgcgagtcaa
     4321 aggatataaa cgtgtccccg aaccacctgc tagaataata cctttcatag tagggtacct
     4381 ttctttgtta ttttagagtc aattactatt aattgtgtac tgctctaaaa agaaaacaat
     4441 catcccatgt tttatatggc tctataatat ttgtagtggg taaatccctt atagatatta
     4501 tggagcctat tttgttgtag aaaaaaagtc ccatatgacc tataatgaaa agcgaccaaa
     4561 caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaact gctcgatatt
     4621 aaagacccaa acatcaagat tctagatatc atcaatatgg atacccacaa agaaattatc
     4681 gctaagctgg attatgaggc tccatcttgc cctgattgtg gaagtctaat gaagaaatat
     4741 gactttcaaa aaccgtctaa gatcccttat cttgaaacga ctggtatgcc tactagaatt
     4801 ctccttagaa agcgtcgatt caagtgctat cactgttcaa aaatgatggt cgctgaaact
     4861 tctatcgtca agaagaatca ccaaatccct cgtatcatca accaaaagat tgctcaaaag
     4921 ttaattgaaa agatttctat gactgatatt gcccatcagc tttccatctc aacttcaact
     4981 gttattcgta agctcaatga ttttcacttt aaacatgatt tttcttgtct tcctgagatt
     5041 atgtcttggg atgagtatgc ttttacaaag ggaaagatga gcttcattgc gcaagatttt
     5101 gaaaagctca atatcatcac tgttcttgag ggtagaacac aagctatcat tcgaaatcac
     5161 tttcttcgct acgatagagt tgtccgatgt cgcgtcaaaa tcattactat ggatatgttt
     5221 agcccttact atgacttggc taaacagttt cgctttcaaa tttctaggct caggctgaaa
     5281 cagtctccca gactgtttca ctcccgaatg ctaaaatcgt gttggatcgc tttcacattg
     5341 tacaacatct tagccgtgct atgagtcgtg tgcgtgttca aatcataaat cagtttcatc
     5401 gaaaatccca tgaatacaag gctatcaagc gctactggaa actcattcaa taggatagtc
     5461 gtaaactgag tgataaacat ttttatcgtc ctacttttcg tatgcattga accaataaag
     5521 agattttaaa caagcttttg agttattcgg aagacttgaa acaccactat caactctatc
     5581 agctcttgct ttttcatttc cagaataagg aaccagagaa atttttcgga cttattgagg
     5641 acaatcttaa gcaggttcat cctatttttc agaccgtctt taaaaccttc ctcaaagata
     5701 aagaaaagat tgtcaacgcc cttcaactac actattctaa cgccaaactg gaagcgacca
     5761 ataatctcat caaacttatc aagcgcaatg cctttggttt tcgaaacttt gaaaacttca
     5821 aaaaacggat tttcatcgct ctgaacatca aaaaagaaag gacgaaattt gtcctttctc
     5881 gagcttagct gacttcaacc cactacagtt gacaaagagc ctaaaaattc acttacttca
     5941 tattacattt agcatgaaat gaaataagcg aattctactt tgtttgcata caattaaaaa
     6001 tcaattccta aggatgtttt aaataactgt gtaaaaggca taatttcacc atttcttagt
     6061 ttttcaatgc taaattacat agtaactgga gagctattag aaatctctaa cttcctcata
     6121 gttaaaaaat gacaatgaga tacttattga tttcaattca ttaacagaat acgaactaga
     6181 caagtgagtt cgtctcctta acaaacactt ccaagcgttt actttcctca ttcagtcgtc
     6241 gtaatctaca acttacatca tcagataagt catactcacc atttagaata gatagaatat
     6301 gttgtttttc ttcttcagtc ttctcttcaa taagcacatt tttaaaaatt actgccatta
     6361 tcagcacctc acttcgaagg aatatatgca actatatcct attaagtcaa tctctactga
     6421 caaaagaagt atatttactt cactaagtgc gagcgagaat atagaaatat ctttattgtt
     6481 ttagatgagt tgtcgctatc ctccagctag tttttaacta ttctatcatt caaatgatat
     6541 agattattag ggactagaaa tatacaaatt gatttaatct ctcttaaaaa tatccctagt
     6601 ataaacttta cccctcacat cttctaaagt ctcatcaaaa cgatttgcaa caatcacttg
     6661 actagatttc ttaaatattt caaaatcatt aactacttga ctaccataga aagtagtacc
     6721 actttcaaga gttggttcgt aaataataat agtaacacct tttgctttca aacgcttcat
     6781 aataccttga atagaagatt gtctaaaatt atctgaatta cttttcattg ttaaacgata
     6841 aattcctaca acaatctctt tttctttatc tggtttatag aaatcattgc ctacataaga
     6901 tccagcaaga tctaaaatac gatctgcaat ataatctttt cttgtccgat tactttgtac
     6961 tatagctgtt atcatttctt gtggaacgtc agaataattt gcaagaagtt gcttggtatc
     7021 tttaggaaga cagtaacccc cataaccaaa agaaggatta ttgtagtgag aacctattct
     7081 cggatctaaa caaactccat caataatcgc ttgagtatct agtcctttca tctcagaata
     7141 agtatctaac tcgttaaaat aggaaacccg gagggcaaga taggtattag caaaaagttt
     7201 tactgcttca gcttctgtaa aatccatata caatgtttca atattttctt tcactgcacc
     7261 ttcctgaagc atttttacaa aaatttcagc agactttacc aaatctttat catctttatc
     7321 tgtacctata ataattcgac tcggatatag gttatcatat aacgcttttg actcccgtaa
     7381 aaactcagga ctaaacataa tattgtctgt aagaaatttc ctccgtactg actttgtata
     7441 tccaacagga acagtacttt taattattat aattgcatca ggattatatt tcataactgc
     7501 ttcaatgaca gcctcgactg aagatgtatc gaaaaaattt tttttcggat cataattagt
     7561 tggagccgca ataactataa aatccgcatt ctcatatgct tcctctgcat tcaatgtagc
     7621 tacgagattc aattcttttt ccgcgagata tttttctata taatcgtctt ggatagggga
     7681 cttcttttta ttgattaact caactttctc aggaatgata tctacggcaa caacttgatg
     7741 atgttgagcc agtaagattg caatagataa tccaacatat cctgtacctg ctactgctat
     7801 tttcataatt ttttcctttc tcaaaacact ctcgttatac attatagtag tctttatacc
     7861 actctgcaaa ctttctcaaa ccttctcgta aagaagtttt tggtttaaaa ccaaaatctc
     7921 tctctaaatc acttgtatct gcataagtaa caggaacatc gcctggttgc ataggaacta
     7981 attttttatg actatcaaaa tcataatttt ccggcaaaac tcctgccttg attagctcct
     8041 gttgaagaac atccacaaaa tctaacaaat tttcgggttt actattccca atattgtaca
     8101 ctttatatgg ggctaacggt aaattatcag atcccactag tttcttcgga gctgattgca
     8161 tgacccttac tatcccctca acgatatcat ctatataagt aaaatctcgt ttacaattac
     8221 catgattata aatctcaata tcggaaccac ttcgcaattt atctgtaaat ccaaaatagg
     8281 ccatatctgg gcgcccagca ggaccataaa ctgtaaaaaa gcgtaagcct gtcgaaggaa
     8341 tattgtaaat ctttgaataa gcatacgctt gaagttcatt tgttttttta gtcgcagcat
     8401 atagtgaaat aggattgtct accttatctt ctgttgcaaa cgggattttt ttatttccac
     8461 catataccga tgaggacgat gcataaacta agtgttccac accaccatca tatatctcat
     8521 acgaatgacg acaagcttcc aacacattat gaaagccaac gatattactt tctatatata
     8581 catctggatt tgtaatggag tagcgtactc ctgcctgggc agctagatta acaacaatct
     8641 gaggatgata actcttaaaa atcttattaa taagcatttt atctgcaata tcacccttga
     8701 taaatatcca gtttttttct ggataatcct gaattagctt attaagttga agcaatcgat
     8761 aatctttaag tgcaatatca tagtaatcat tcaaattgtc caaaccaatg attgtcatcg
     8821 ttccttctaa ttccaataat ttcctaacca gatttgatcc aataaaacca gctactcctg
     8881 taattagaat tgtttttcct ctcatatcat aatacctctt gttattttta tattttcatc
     8941 cactaataca cattctttaa caactattat aatcaatttc taagataatc tataataaaa
     9001 aacaaaccac atacagtata agagattgct gatgctatcg cagctcctgt aatttggtag
     9061 ttaggaatta agtaccagtt taaacttata tttatcaaag ccgacacaga taaaattttt
     9121 atagctacac tctgtttacc ctgagatata taaattggtt gtaaaatttt aaagaaaatc
     9181 atcgataagc ttcctaaaaa aatgactaat gttataggaa atgcctttat ataactggaa
     9241 ccataaagga gcgtaatcgc aaattctcca aaagaaagaa atccaataat taataaaatc
     9301 ataaatagaa atgatacttt tattgcattt attgctttat ttttctcaaa agttctttta
     9361 gccgaatcac caaataaaat ctctttaaat gagtctggaa ccatcaaaaa catattagaa
     9421 aacgtaactg cgacactgta tatacctaca ttataactac tagacatttg cttcaacatt
     9481 atgatatcaa tactataatt aaatgtaatt aatagagtaa gaatcataga aagaaatcca
     9541 aacttatata tagtgaaaaa ttctttaata ctaatatgtt caaaaactgg gaacatattg
     9601 taatagtata aaaataaaat gatacgtaaa aattcattaa tagcatatac caaaaatacc
     9661 atctctatag aaactaaatg aaatagtaac aacaatacta gcataacgga atatactacg
     9721 cttactccta atacaatctt attcctcttt atactatttt ctattactgc aatcatagta
     9781 agatttgttc tcataataga tagactggac aaaactatta ttaccccacc ataatctatc
     9841 ggaacatcag ctaaaactat tattaaacct attattccaa acaataatcc ttgaataaaa
     9901 gttaaaaaaa caaatttatt ctgatactca ttagaatgat tccttttaaa ggtcgagtaa
     9961 gcctgaccta aaccaactcc acctaaaata taaaaaattt ctactaagtt cattacatag
    10021 gcataatctc cttttttttc aacacctaat cccctattaa ttataattga ggataaaagt
    10081 gttaataaga ttaacaaaaa tttactcgtt aaagcaaacc aatatttctt agatagtctc
    10141 acttattttc tccgtatgtt aaattttata acagtaaatt taaaattata gtatattgaa
    10201 atagaatatg aacaaaacga ttagggaatt taaagtaatt tataaaaatt ctttagaagc
    10261 tgcattgtac tactccaact tcaaaccact atagtatcaa aaagtatacc ccaccttttt
    10321 aaataaacta ctcaccaccc atttcatcca atggtgatat caacaccatt ctattgataa
    10381 aaacaataac caatgttccc aatatagcat atttaagtaa tggagataat atgttagcaa
    10441 aatcagcacg agtagaataa ataaaaatag gtatcatata cagatatatc agcatcccgt
    10501 atatatttct ttgagcgttt atataaagaa atctcatcaa aaagcctgtt agcataaaaa
    10561 tcattacaat tccaaagtat cctccattca catatccctc tcccacaaga gtaaaaccat
    10621 atttggttga atgtacgttt ggaaaaaagg tgtccataaa ccaagtttga ttagaatacc
    10681 ccgtattata aaaaattctt actatgtcat taaaaaaaga acgaccttcg aaataattgc
    10741 ccatattatg taatatcaga atctgtaaat tacgactagc tgatacaaac tcaccatcta
    10801 gcaaatcaaa ccaaatatta tttgtattta tagatgaaac ttgcccactt aataaagtat
    10861 atttaaaaac tgcagataac ggaatcagta gtgccgcaag cggaactaac attacaagat
    10921 aaaaacgttt tattttgtga aagtaaaata atataatcac atcaaggatg aataaagtaa
    10981 acatataatc tctttcccct gtaacgatag agaagagaca gataactatc gctgtgttag
    11041 tattacaatt tagtagtctc cattttttag tactcaactg tataaatagc tgatatgtat
    11101 gaatgagaat cataaaataa accaaagaaa atactaacat tatcacaata ttggcacctg
    11161 aatatatttc ccctttattt ctaaaaccac ttcctaatag atatataatt gctactgttg
    11221 tgataaacga attcatatta ttgagaaata ataaatagtt attgttattt aggtttattt
    11281 tcctttcgct taacacaatg gctttagaag gtagagttaa caacaaagtt gccaaagcca
    11341 gccattgcat gaaaatcaaa tcttttgtat aaccatagtt tatatactcc attctataga
    11401 gtagcgggta agaaatagaa taaatagtaa agaagctact ataccacaca tagggatgaa
    11461 aaatattaaa tttcacaatt atcattgcca taaaacttaa aaaaatcatt gaaaataatg
    11521 gaattgtaac atcattattt tcactgcata aaattaaagt ccctgaaaaa actacaccta
    11581 ctagaagtat tattttattt tttatatcat ttgattgtag actaaacttc atttactttt
    11641 ttcctttaac taataattta aacgtaatgc gtattcaaaa atttgattgg ctatgtagtc
    11701 agtttttata gcatatttaa tatatcgaaa cggattttcc atcgcatttt aatctaaacc
    11761 atcagaatta tttaattctc ttctaatttg agcaaaatag tcacttctgc gtttatttaa
    11821 tacactcgaa agaaattttt ttgagaattc aaactgtttt atcaccatct tttccttatc
    11881 catactaata aaatctataa tagatcccgc aatcgcttgt gaagaggatg gagtaaatag
    11941 acaatgtggc cccagcaact ctggaattcc tgctttatta gaccctatac aagggcaagc
    12001 acggctcata gcttcaatta ccgcacgagg taacccttct tgtaaacttg gttgtatata
    12061 taaatcaact ttatccaaat actcataaat ttgtgatgta gtcaattccc ctaaaaaatg
    12121 gattctattc gctactccca attcctctgc tttctttttt aagaaacttt gatcaccatc
    12181 acctgctaaa taataatcca acaaaatacc ttgtatttct aatctcttca ttgcttccaa
    12241 tacaaatcta tggcccttgg ctcgtacatt cacagatgct gttgtcatta ttgaaatttt
    12301 ttgaggatta aattttttca acttataaag acggctcttc aaagatctat tctctacaga
    12361 ggtaatatta acatttgaag caacgatatt agatttaata ttaggatatc tatcttgtaa
    12421 atatttttct gtcacgtata tgcaataatt agcgtttttt acaattgatt tagttttggc
    12481 gtatatatat ggagctaata attttccctt taaactatga taccagtaag aatcccaagc
    12541 atcccccatt atttctgtca gatacggctt acctatcttc aatgcgtagt ctgcagtttt
    12601 tgatccaatt atagacggaa tacgaacaac tattaagtcg ctatcaatca ttccttcaat
    12661 aatcttattt ttattttgac caaatagaac ctgatgtaga ccttctatag ggataaattt
    12721 attaataaag ttcgctttat gatatccttc agggtatgat tccaccttct cataacgact
    12781 acatagtaca atctctccaa atgctttagc atagcgctca taaataaaat aagctttcgg
    12841 ttttaaatat atttcatttt tatagattgt acatctaaat tcagtcgcta taaatacttt
    12901 cataatttca tctcccttga taaacgtttc tgaataaata tagtatcagc tggaatatcc
    12961 tttgttacaa cacttcctgc tgcaaccaca ctattctcac caatactcac tcccttcaag
    13021 acaatgctgt tagctccaat ccaaacattt tctccaatca taactggggc cgtcttaaat
    13081 ttttttgctt tcaatccacc tggaacacta acatcatagt catgatcata tataagtact
    13141 ccaggaccac attttactcc agatttaata tctatgtatt tacgacaagc tatcatacaa
    13201 ttattactca aaaatacatc atcagaaatc ttgagttttg ctccttttct aactttcaat
    13261 actcccccgg cgtttactct aatctttttt cctaagatta atttagcatt agattcctgt
    13321 tcgacagtta cattctttcc aaattttaaa aaataatgaa aagtaagatc cttgtttcga
    13381 cacactttta ataatatcaa gcaaatattt gcacgaagta aaccaacaat attttttata
    13441 atcctattca tctaaagctc cttttatttt atctaaataa gcatctataa taatttgacg
    13501 agaaaaatat tgctctatat acattctccc ttgaagtccc atctcttttc gtttttcatt
    13561 ttctagacct aaaaaaactt ccaatataga gactagttcc tcaacatttc ccccttgaaa
    13621 tatatagcct gtctctctat ctttaacaat ttctttgcaa cctggattat ctgtcgtaat
    13681 taaaacacgt cctgaactag cgttttctag taatacattg ctcattcctt caccatacac
    13741 actgggatgg ataattgcat gggaacgggt aatatgaggt atcacatctt tttgttgtcc
    13801 caaataataa acgattcctt ttttttctaa gtcacaaatt ttaagttcat aattactctc
    13861 tgtcggttct ataaagccaa taatattaaa ctctgttttg ggatatcgac tcttaataat
    13921 ttgggcagca gccagataag tatctatacc tttttctttt aatatcctac caataaaatt
    13981 aaaaacgatt gtttctcctt gaattccatt tccaccattt ggatactgtt gcacaggata
    14041 cttttcaatg ttcactcctg acccaggtat cagcttagag tcacccaaaa tcaagccaag
    14101 agtttttaac attttcatat tatattcatt ttgaaaaaaa acacaatttg atttcctaaa
    14161 agaaattcta aacagtaata acaccaggct tcttacacaa gaacccattg ttaagacact
    14221 acctaaacct gttacgttat ttatatattt tattcctaaa attgttgcag ctaggctagc
    14281 atatacattt ggtttcacgg tatatgtcaa gactacatcc ggtctatatt ttctcaataa
    14341 tcttatataa ctaagaaata gacgaatatc ttttaaaggg tttattcctc ttctatcaat
    14401 agtaatatct tcatactcaa attgaataga cttcatcaac tctatcttat ctccataagg
    14461 acatgacact agcacttcat acccatactc aactagtgac tctataactt cttttcgaaa
    14521 acaatagata tcatcgtcat gattagttat taacataatt tttttctttt gtaaattcat
    14581 caaaataatc ttcctaaaat ataattaacc gctactccat tatcctttac aactatcatt
    14641 ttaaaaatag taattttcta taagtaattg tttccaaatt gtgacacttt aaaattctat
    14701 acacatatag aacttacaaa ctatttacga ccgtaaactc catacttatc aaccgagata
    14761 tccaatttat ttaaaacaac tcccaggaac agtttccctg tttgttctaa ttgttgtttc
    14821 gctttttgga catcacgttt attcgcctca cctgttgctg ttatcaagat ggacgcatca
    14881 cacttttgag tgataattgc cgcatcaata acaattccaa taggtggtgt atcaacaatg
    14941 atataatcaa aatatttacg caatgtttca atcatatcat taaaattttt actttgtaac
    15001 aaggctgtag ggtttggtga tacagatccc gattgaacta caaataaatt ttcaatattt
    15061 gtatcacata aaccgtgaga taaatcagct gtcccagata aaaattctgt tagccctgta
    15121 attttttcac gagatttaaa aaatcctgac ataactgaat ttcgaatatc gccatcgaac
    15181 aaaagagttt tatagcctgc acgcgcaaat gacattgcta tatttacgga agtagttgtt
    15241 tttccttccc ccggattaac agaagtaacg gaaattactt ttagtttatc tccgctcaac
    15301 tgtatatttg tacacaaggt attgtaatat tcttctgcct tcttaatgaa ctccagtttt
    15361 ttttgtgcta tttctaatgt cggcatctct ctctcctatt tcaacttacc caagtttggt
    15421 acaactccca aaagtgtcat ctgcagtgca ttttcgatat cttccggacg tttcacacga
    15481 gtgtccaaaa gttcaagaag aagaactata acactagttc caatcacccc tgccaaaaaa
    15541 ccaattagtg tattgcgttt aatatttggc gaagacggtg atatcgccgg tcttgcctcc
    15601 tccagtgttg tcacatcaga aacacgagta atactgataa ttttttgagc agctacttct
    15661 cttaaagagt tagcgatacg gcttgcctct tcaggaactc gatcactaac tgaaacagag
    15721 acaatacggg tatcaactgg tactgttact ttaattttat tagccaaacc ttttggcatc
    15781 aaatctagtt tcaaatcaga aataacttcc tccaaaacat cctgcgatag gacaatttca
    15841 cgatagtctt taaccaagta tgctcctgcc tgcaagtctt gattggttaa accaggcttc
    15901 tctccctgat tacggttaac tacataaatc cgagtcgtac tagtaaactc aggtttgata
    15961 acaaaagtac tgtaggcaaa agcaactgaa gaagttataa ttgccactaa taaaatgacc
    16021 aactttcttt tccataaagc tctgaatagt tgcaatacat cgatttccaa agtgttttgt
    16081 tccttcatat tttctcctaa attaattgat ccattataat ttttctggga ttatctacaa
    16141 aaagttcttt cgcttttttc gctccatatt tcttagcaat gatatcatat gcctgttgca
    16201 tatatggagg tctactgtct aaattgtgca tgtcacttgc aactacatga actaaatcac
    16261 gttccaaaaa ataccgagct ctctttttca tgaatttata tttttcacca aagaacttag
    16321 gttttgaaac atgataacta tttatctgag tatagcaccc catatcaatc agttcacgaa
    16381 cacgtttttc gttattctct aaagcatcat aacgttcaat atgagcaatt actggcgtga
    16441 ttcccaacat caaaatattg ctcaatcccg tatgaatctg acgataggaa gtatgcatgc
    16501 taaactcaat caaggcataa cgactatcat taagggtagg aatttctttt ttttctagct
    16561 tttctagagc atccagagta tagtatatct ctgcgccata agcaatgact aaatcatctg
    16621 ctacttcttt tgcaatttcc cgaacctgaa gaaagttttc tgctatcttc tcttccggag
    16681 tttcaaacat gcccttgcga cggtgagagg tagagacaat ggttctcacc ccctgcctgt
    16741 aggattctgc caagagagcc ttgctttcct ctcttgactt gggaccatca tctacatcaa
    16801 agacgatgtg cgaatggatg tctatcattt tatctaccct ccatcacatc ctgtatagct
    16861 gctttaacta cagttaaact actatcatct atttccatca catagaggtt actgtctggc
    16921 attgcataag aaggaagatc catccgacct gtccctttta aatcttgaga atttacttta
    16981 taattccctc cactttccaa ctgagtattc actaaatcta tcatagtctc aatcggtata
    17041 tttgtttgaa gagaatcctg caatccttga agaatactac tatagttttt caaaacctct
    17101 gtagaagtta acttctgaat aattgctaca atgacctttt gttggttgcg accacggtca
    17161 cggtctccat cggttagtga gtagcgttca cgtacaaaac ctaaagcttg ctcagagtct
    17221 agatggacat tccctactgg gaaatggaac ttcccatgta gagctgaaaa ctcttgatca
    17281 ttatgaacat ctacccctcc caataagtca atcattttca agaaagaagt gaagttcaat
    17341 cgcacatagt aattgatatc cactccatag agattttcta aggtgtgaat ggacgaatca
    17401 actccataaa tgcccgcatg ggttaattta tctttttgat tatttccact atctgcgatt
    17461 ggtacatagg catcacgtgg cgttgtggtc aagaggattt tcttggtatc tcgattgaca
    17521 gtcattagga tattgacatc tgatcgcgac accgaactaa taggaccata ggtgtcaatt
    17581 ccactaacat agatattgaa agactgattc ttagacgtct taggagcctc tactttttta
    17641 gtgaatccct tggtataaat cttttttatc ttcgatgcgt agtctggata ctctgactcg
    17701 atgatatttt caaagacact atttaggaca atggccttag tctcccctgc aatcaaactc
    17761 ttgtaagctg ccaagtaaga cgaactctgg ttgaccgtca aatcggtatt ctgacttgac
    17821 ttgatatcag ctagtagttt ttgaatattt tcattatcag tcccagtcgg tgctgtcaca
    17881 ctcgtcagtt gcgtaacatt ttcgatctta ctatctgcta aaacagcgac actgattgaa
    17941 tattctgagt aattagaagt cgcatttaaa cgattggtca gtccaacaaa ctgctgtact
    18001 gcaaagagcg acactgagct gacaaggata gagaacagca acagaaaaat agtaaacttt
    18061 tcagcttttt tatagataat caagagtagc cctaccaagg caactagtag gactaacgca
    18121 gttaccacta ggttaagata tctaaaagca aggatattgt acttaaagat taagaacaat
    18181 aaaaaacaaa ttaacaataa ataaatagtc agcaaaacga tattaacact tcgcttcact
    18241 ttctgtgaac gtgatttttt aaaacgtcta ctcatgatta acacctatac cttgaacatc
    18301 atacaattat atcacttttt tacggtaatg tctacacctt tattttcact atctgcatct
    18361 ttaagtatct tagtagactt cccgcgaacc aaaaatatag taaaatgaaa taagaatagg
    18421 acaaatcaat caggacagtc aaatcgattt ctaacaatgt tttagaatca gatgtgtact
    18481 attctagttt caatataa
//
LOCUS       DAVBOH010000039        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOH010000039 DAVBOH010000000
VERSION     DAVBOH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.039"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ873_001559"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ873_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ873_001560"
     CDS             657..1316
                     /locus_tag="VQ873_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3107797.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ873_001561"
     CDS             1341..2408
                     /locus_tag="VQ873_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3107798.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ873_001562"
     CDS             2511..3521
                     /locus_tag="VQ873_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107799.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ873_001563"
     CDS             3533..5224
                     /locus_tag="VQ873_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3107800.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLLFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ873_001564"
     CDS             5227..5937
                     /locus_tag="VQ873_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3107801.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ873_001565"
     CDS             6033..6224
                     /locus_tag="VQ873_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107802.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ873_001566"
     CDS             6509..7510
                     /locus_tag="VQ873_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3107803.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8118..8192
                     /locus_tag="VQ873_001567"
                     /pseudo
     CDS             8118..8192
                     /locus_tag="VQ873_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ873_001568"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ873_001568"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3107804.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ873_001569"
     CDS             10009..10575
                     /locus_tag="VQ873_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3107805.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ873_001570"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ873_001570"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3107806.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ873_001571"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ873_001571"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3107807.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ873_001572"
     CDS             12341..12940
                     /locus_tag="VQ873_001572"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3107808.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ873_001573"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ873_001573"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3107809.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ873_001574"
     CDS             14134..14910
                     /locus_tag="VQ873_001574"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3107810.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ873_001575"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ873_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ873_001576"
     CDS             15212..15352
                     /locus_tag="VQ873_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107811.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ873_001577"
     CDS             15389..15943
                     /locus_tag="VQ873_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107812.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ873_001578"
     CDS             15958..17109
                     /locus_tag="VQ873_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3107813.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ873_001579"
     CDS             complement(17161..17820)
                     /locus_tag="VQ873_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3107814.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ873_001580"
     CDS             17890..>18308
                     /locus_tag="VQ873_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107815.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2958 c         3938 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattgttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBOH010000040        18177 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOH010000040 DAVBOH010000000
VERSION     DAVBOH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.040"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ873_001581"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ873_001581"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3107816.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ873_001582"
     CDS             complement(863..2125)
                     /locus_tag="VQ873_001582"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3107817.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ873_001583"
     CDS             complement(2135..3265)
                     /locus_tag="VQ873_001583"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3107818.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ873_001584"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ873_001584"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3107819.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ873_001585"
     CDS             complement(5231..6118)
                     /locus_tag="VQ873_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3107820.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ873_001586"
     CDS             complement(6108..6569)
                     /locus_tag="VQ873_001586"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3107821.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ873_001587"
     CDS             complement(6566..7474)
                     /locus_tag="VQ873_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3107822.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ873_001588"
     CDS             7467..7664
                     /locus_tag="VQ873_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3107823.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ873_001589"
     CDS             complement(7716..8387)
                     /locus_tag="VQ873_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3107824.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ873_001590"
     CDS             complement(8441..8662)
                     /locus_tag="VQ873_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3107825.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ873_001591"
     CDS             8934..9743
                     /locus_tag="VQ873_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3107826.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ873_001592"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ873_001592"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3107827.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ873_001593"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ873_001593"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3107828.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ873_001594"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ873_001594"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3107829.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ873_001595"
     CDS             complement(13018..14277)
                     /locus_tag="VQ873_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3107830.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ873_001596"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ873_001596"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3107831.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ873_001597"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ873_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ873_001598"
     CDS             complement(16071..17546)
                     /locus_tag="VQ873_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3107832.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5331 a         4168 c         3325 g         5353 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctga
//
LOCUS       DAVBOH010000041        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOH010000041 DAVBOH010000000
VERSION     DAVBOH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.041"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ873_001599"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ873_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3107833.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ873_001600"
     CDS             complement(881..1867)
                     /locus_tag="VQ873_001600"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3107834.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ873_001601"
     CDS             complement(1830..2630)
                     /locus_tag="VQ873_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3107835.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ873_001602"
     CDS             complement(2880..3260)
                     /locus_tag="VQ873_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3107836.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ873_001603"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ873_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3107837.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ873_001604"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ873_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3107838.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ873_001605"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ873_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3107839.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ873_001606"
     CDS             complement(4805..5989)
                     /locus_tag="VQ873_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107840.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ873_001607"
     CDS             complement(5993..6580)
                     /locus_tag="VQ873_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3107841.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ873_001608"
     CDS             complement(6613..6801)
                     /locus_tag="VQ873_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107842.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ873_001609"
     CDS             complement(6980..9220)
                     /locus_tag="VQ873_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3107843.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ873_001610"
     CDS             complement(9204..9854)
                     /locus_tag="VQ873_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3107844.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ873_001611"
     CDS             complement(9922..10491)
                     /locus_tag="VQ873_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107845.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ873_001612"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ873_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ873_001613"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ873_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ873_001614"
     CDS             complement(12409..12909)
                     /locus_tag="VQ873_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107846.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ873_001615"
     CDS             complement(13089..14057)
                     /locus_tag="VQ873_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3107847.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ873_001616"
     CDS             complement(14143..14358)
                     /locus_tag="VQ873_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3107848.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ873_001617"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ873_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3107849.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ873_001618"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ873_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3107850.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ873_001619"
     CDS             complement(15847..16584)
                     /locus_tag="VQ873_001619"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3107851.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ873_001620"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ873_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3107852.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5188 a         4137 c         3375 g         5438 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactc
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOH010000042        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOH010000042 DAVBOH010000000
VERSION     DAVBOH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.042"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ873_001621"
     CDS             3..308
                     /locus_tag="VQ873_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3107853.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ873_001622"
     CDS             356..1831
                     /locus_tag="VQ873_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3107854.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1854..1931
                     /locus_tag="VQ873_001623"
                     /pseudo
     CDS             1854..1931
                     /locus_tag="VQ873_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2091..8792
                     /locus_tag="VQ873_001624"
     CDS             2091..8792
                     /locus_tag="VQ873_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3107855.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYEFITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ873_001625"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ873_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ873_001626"
     CDS             complement(10107..10466)
                     /locus_tag="VQ873_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3107856.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ873_001627"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ873_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ873_001628"
     CDS             11498..12055
                     /locus_tag="VQ873_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3107857.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ873_001629"
     CDS             12048..12302
                     /locus_tag="VQ873_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107858.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ873_001630"
     CDS             12314..14368
                     /locus_tag="VQ873_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3107859.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ873_001631"
     CDS             14547..15407
                     /locus_tag="VQ873_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3107860.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ873_001632"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ873_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3107861.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ873_001633"
     CDS             16356..16922
                     /locus_tag="VQ873_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3107862.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ873_001634"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ873_001634"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3107863.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3451 c         3978 g         5227 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tcattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagcaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOH010000043        17892 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOH010000043 DAVBOH010000000
VERSION     DAVBOH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.043"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..777
                     /locus_tag="VQ873_001635"
                     /pseudo
     CDS             1..777
                     /locus_tag="VQ873_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1093..2067)
                     /gene="pta"
                     /locus_tag="VQ873_001636"
     CDS             complement(1093..2067)
                     /gene="pta"
                     /locus_tag="VQ873_001636"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3107864.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(2111..3007)
                     /locus_tag="VQ873_001637"
     CDS             complement(2111..3007)
                     /locus_tag="VQ873_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3107865.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(3004..3822)
                     /locus_tag="VQ873_001638"
     CDS             complement(3004..3822)
                     /locus_tag="VQ873_001638"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3107866.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3806..4477)
                     /locus_tag="VQ873_001639"
     CDS             complement(3806..4477)
                     /locus_tag="VQ873_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3107867.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            4605..5174
                     /locus_tag="VQ873_001640"
     CDS             4605..5174
                     /locus_tag="VQ873_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3107868.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            5287..6246
                     /locus_tag="VQ873_001641"
     CDS             5287..6246
                     /locus_tag="VQ873_001641"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3107869.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            6256..7371
                     /locus_tag="VQ873_001642"
     CDS             6256..7371
                     /locus_tag="VQ873_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3107870.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            7376..7723
                     /locus_tag="VQ873_001643"
     CDS             7376..7723
                     /locus_tag="VQ873_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3107871.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            7731..7946
                     /locus_tag="VQ873_001644"
     CDS             7731..7946
                     /locus_tag="VQ873_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3107872.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            8029..8670
                     /locus_tag="VQ873_001645"
     CDS             8029..8670
                     /locus_tag="VQ873_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3107873.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            8688..9377
                     /locus_tag="VQ873_001646"
     CDS             8688..9377
                     /locus_tag="VQ873_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3107874.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9374..10054)
                     /gene="radC"
                     /locus_tag="VQ873_001647"
     CDS             complement(9374..10054)
                     /gene="radC"
                     /locus_tag="VQ873_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3107875.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(10097..12388)
                     /gene="pcrA"
                     /locus_tag="VQ873_001648"
     CDS             complement(10097..12388)
                     /gene="pcrA"
                     /locus_tag="VQ873_001648"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3107876.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(12579..13384)
                     /locus_tag="VQ873_001649"
     CDS             complement(join(12579..13007,13010..13384))
                     /locus_tag="VQ873_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3107877.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(13764..14624)
                     /locus_tag="VQ873_001650"
     CDS             complement(13764..14624)
                     /locus_tag="VQ873_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3107878.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(14640..15917)
                     /locus_tag="VQ873_001651"
     CDS             complement(14640..15917)
                     /locus_tag="VQ873_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3107879.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(15910..16461)
                     /locus_tag="VQ873_001652"
     CDS             complement(15910..16461)
                     /locus_tag="VQ873_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3107880.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(16477..17736)
                     /locus_tag="VQ873_001653"
     CDS             complement(16477..17736)
                     /locus_tag="VQ873_001653"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3107881.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         5434 a         3902 c         3262 g         5294 t
ORIGIN      
        1 aaatccctcg tatcatcaac caaaagattg ctcaaaagtt aattgaaaag atttctatga
       61 ctgatattgc ccatcagctt tccatctcaa cttcaactgt tattcgtaag ctcaatgatt
      121 ttcactttga gcatgatttt tcgcgtcttc ctgagattat gtcttgggac gttgaaacag
      181 tccggggagt gactgtttca atcgggagat ggagatgagc tttattgctc aggactttga
      241 taagctcaat atcataactg ttcttgagag cagaacacaa gccatcatcc gaaatcccat
      301 gaatacaagg ctatcaagcg ctactggaaa ctcattcaac aggatagccg taaactgagt
      361 gataagcgat tttatcgtcc tacttttcgt atgcatttaa ccaataaaga gattttagac
      421 aagcttttga gctattcaca agacttgaaa catcactatc agctctatca actcttgctg
      481 tttcactttc agaataagga accggagaaa tttttcggac tcattgagga caatctaaag
      541 caggttcatc ctctttttca gactgtcttt aaaacctttc taaaggacaa agagaaaatc
      601 gtcaacgccc ttcaactacc ctattcaaac gccaaattgg aagcgaccaa taatctcatc
      661 aaacttatca agcgcaatgc ctttggtttt cggaactttg aaaacttcaa aaaacggatt
      721 tttaccgctc tgaatatcaa aaaagaaagg acaaaatttg tcctttctcg agcttagctt
      781 ttcttcaacc cactacagtt gacaaagagc cagaaaacgc ataatagcag gtgtcaagac
      841 acttaatatt atgcgttttc tcatgaaaaa attctctttt catactcatt taaaatcaaa
      901 aagggaaatt atcgttttac ggacatacat attacagatt tctataggtc gtgtatagac
      961 aggatatcat cgcttggaag ttttcctttt tgacaccaat cagtaattta gttctcagga
     1021 attaatggca gtgcttttcg tacatagttt cataactaca gtatagcata gtatatcgct
     1081 ttatagtttt cactattgat gaactgcttg agctgctgtg atgagggtca acttgtaaac
     1141 atcatctgca ttacatccac gagaaagatc attaactggc ttgtttaaac cttgcaaaac
     1201 aggtcctaca gccgcaaagc cacccaggcg ttcagccatc ttgtaaccga tatttccggc
     1261 ctcgatacct gggaagatga agacatttgc ttgaccagct accgtacttc caggagcttt
     1321 cagagctgca gtttcaggaa caaaggctgc atcaaattgc aactcaccat cgatttcaag
     1381 gtcaggacgc aagtcgtgag caattttagt tgcttcaacg accttatcaa cgctttcacc
     1441 aaaccctgaa cctttagtag aatagctcaa catggcaatt ttaggttcga tgccaaacat
     1501 cttagctgtg attgctgagt tgatggcaat ttcagccaag gcttctgcat ctggattgat
     1561 gttaatggca cagtctccaa ataggtaacg ttccgtacca cgaaccatga ggaaggctcc
     1621 tgaagtacga gttacatttg gacgagtttt gatgatttgt agagctggac gaactgttga
     1681 agctgttgag tgaatcgctc ctgacaccat tccatcaacc aagcccaagt aaaccaacat
     1741 cacaccaaag tagttgacat cttcaaccaa aaccttgcgt acatcttctt cagtcatttt
     1801 gcccttgcga cgctccacca aggcagaaac catttcttca aattgaggat aatgttgagg
     1861 gtcgatgacc tcataaccat ccatgattcc ttcaatttca agataaattt taattttttc
     1921 aggatttcca agcaaaacag gaatcacttc tgtttctttt actaagcgtt ttgttgcttg
     1981 aagaatacga ggctcttccc cttcagggag aacgatacga gcatttttac caacaaggtt
     2041 ggctttgaga ctttcaaaaa cttccatgag ttttctcctt taagataata attatactct
     2101 gagacagttt ttatagagta ttagttgata actgggtaat aaggttactg aaatcatccg
     2161 gcaagggact ttctaactgc aagtcttgct ctaaaaatgg atgataaaag gataggtaat
     2221 ggcaatgcag agcctgacgt tgaataccat cttccagact accaccatac aaatcatctc
     2281 ccagcaaagg aaaaccgata tgagaaaaat ggactcggat ttgatgggtt cgaccagtgt
     2341 gcaggtgaat atagaccaag tgaatatttc cataagaagc tacaatcttg tatgaagtat
     2401 gggcatactt tccgccttta gccactcgtc tggtaataat ggaatcttca tcacgcgcaa
     2461 tcggagcaat aatttcccct tctggctcca aatgtccatc tcccttaacc aaagcaaagt
     2521 agcgtttctc gatagatttc ttctgcaact gcttgtctaa tcgtgcatgg gcataaccgt
     2581 gcttggcaaa gagcatcaag ccagaagtgt ccctatctag tctggtaaca atgtgaacct
     2641 gctgattttc ataattttgc ttgacatagt aacccttgat aaaattggca atggtgttag
     2701 agtgattgac actaggaata gaagccactc catagggttt attcaagact agaaagtggt
     2761 catcctcata gagaatatct aatggatgct caatagcctc caaggtttca aagccttcct
     2821 cagcgggaat gtaaatggta acgtagtctc caacgtccaa tagatacgtt gcattttgcg
     2881 gttgattatt gaccagaata gctccacctc gaaacttaat cttagccagc aatcccttag
     2941 aaacctcgtg cttttttaaa aaggtcttaa ccttgacatg ttcatctgcg ataaattcaa
     3001 acctcattca tccacctcac cgataaaggc atccttaaca cggttccaga aactggtatg
     3061 gctaggagtc gcgacaaagt gaatcttatg atggtcgatt tgatactcaa tacgctcaat
     3121 attacggaaa gaataaacgc tattgtcaac cgaaatagta tgataatcgt ttcttgttgg
     3181 aataagttca atcttatcct tcttaggcac aataatggaa gagcccagtg ttcgataaac
     3241 acgattatta aggctggcaa tttccgttaa ttgcaaagct tcaatggtag ggtgtaaaac
     3301 agcaccgcca agagacttgt tataggcagt actaccagtc ggtgtcgaaa ctgttagccc
     3361 gtctccacga aaacgttcaa agggaacacc atttattaca atatctgcca ccatggttcg
     3421 atcagacctg cggatgctgg cttcgttgag tgctctgaaa atcttaactt caccattttc
     3481 aagaaagacc ttcacattca gaacagggta agaaaccctt gccccagtat ctagctgcaa
     3541 attagtcact agcttgtcca actcaaaatc acgataatct gtatagaagc ccaaatgtcc
     3601 agtatgaaga ccgataaagc ggaccttgtc aagctgattt tcgtacttat gaaaggccga
     3661 caagagcata ccatccccgc caatggaaat gacaatatcc ggattggtat cattgagtat
     3721 aaactgattt ctcttcaaac gatctcgcaa ttcatacaaa accctttgac tctgcggttt
     3781 tctattggct atcagatcaa ttcgtttacc tgtattcttc atctgtatcg tcactgtttc
     3841 ctacaccgtc atttaatttt ctactcaaag gatcaaaaag tgcctgggct tcttggatat
     3901 catcacgaat ttcacccatt tcttcatcca actgatgggc gattctagct gtaatttcca
     3961 gtcgcttctt aatctcatct gggaaatccc cttggtactt gtagttgaga gaatgttcta
     4021 tcgttgccca gaaattcatg gccaaagtac gaatttgaat ttctgccaaa atagtcttag
     4081 ctccattgat ggtatcaacc gtatattcta ctaccacatg ataggaacga tagcctgatg
     4141 cttttctatg agtaatgtaa tctcgctcct gtatgattcg catatcctga cgcttgtgca
     4201 aaatatccac tacttccttg acgtcatcta caaactgaac catcacacgt aagccagcaa
     4261 tatcctgcaa atcgtgttcc aaggtcgcat aagtaatgcc acgacgagcc attttttctt
     4321 tgatgctctc aattggcttg actcgaccgg tcacaaactc aattggagaa tgcttatttt
     4381 gcttacgata ttgcttacga ataccacgaa gtttaatctt taactcacca acagcttgaa
     4441 tgtaaggatc tagaaattct tcccattcta aggtcatata ttctcccttg ttctcatatt
     4501 atccgtcaaa aatatctttg attttttctc cagattcata tacaataaat acaatgctta
     4561 ttataccata aatccgcttt caacgataaa aaaaggtaag aaaaatgaaa catttagaaa
     4621 ttgaattgaa aacactattg aaaaaagatg aatacaatcg tctaaaagac cagttcacag
     4681 gtgtcactcc tgttcttcaa acaaattact acatcgacac gcctgatttt gaactgcgag
     4741 aaaagaaagt cgctatgcgc attcgaacct ttgaagactg ggctgagttg acactcaaag
     4801 tcccgcagag tgttggaaac atggaataca accaaaaatt gcaactaaaa gatgctgagg
     4861 actatctgag taaggaagaa cttcctcaag gactagtact ggatgaattg gcgaaacatg
     4921 gtatccaaag taagaactgg caggttcttg gttgtctaac aacgcttcgc tatgaaatga
     4981 aaacagctat tggtctcatg gcactggatc agagccgata ctttgatata acagattacg
     5041 aattggagct tgaagtggaa aatcatgagc aaggcaaaca ggatttccga caatttttag
     5101 agaaaaatca gatttcctac caaaaagctc cttcaaaatt ggttcgattt gtcaaaagta
     5161 tgaaaaatag ctgaaataat ctccattttt tggtaaaata gaaaagataa aaatacacaa
     5221 atcccagttc atatatgtaa ggtaaatata actaggattt ataaagttta cagaggacgg
     5281 tctataatgt cagatagaaa aaacatgaaa cttttcgcac tcaactctaa ccaagagatt
     5341 gcacaaaaaa ttgcccaagc tgttggtgtc ccacttggaa aactatcatc acgtcaattt
     5401 tcagacggag aaatccaagt aaatatcgaa gaaagtgtcc gtggttatga tgtttacatc
     5461 atccaatcaa caagtttccc tgtcaacaac cacctaatgg aattgttaat catggtcgat
     5521 gcttgtgtgc gtgcaagtgc ccacagtatc aacgttgtcc ttccatattt tggctatgca
     5581 cgtcaagacc gcattgcttg tcctcgtgag ccacttacag caaaactagt tgccaatatg
     5641 ctggttaagg ctggagttga tcgtatcctg actcttgatt tgcatgccgt tcaggttcaa
     5701 ggtttctttg atattccagt ggataatctt ttcactgttc ccctattcgc aaaacattac
     5761 tgcgataaag gattgcttgg ttcagatgtt gttgtcgtta gccctaaaaa ttcaggtgtc
     5821 aaacgtgcgc gtagcctggc tgaatatctt gatgctccta tcgccattat cgactaccct
     5881 caagacgatg caactcgtaa cgaaggttat attattggtg atgttgaagg taagaaagct
     5941 atcttgattg atgatatttt aaatacagga cgtaccttct ctgaagcttc taaaatcgtt
     6001 gaacgtgaag gagctacaga aatttatgct gtttctagcc acggtctctt cgtcgaggga
     6061 gctgctgagc ttcttgacaa tactaatatt aaagaaattc ttgtgactga ttcagtagca
     6121 acaaaagaaa aaactcctaa aaatgtatgc tatatcactg ctagtgagtt aattggtgat
     6181 gctatcgtac gtattcacga aagaaaacca gtcagcccac tctttgccta caataaaaag
     6241 aaataaggtg attctttgat ttatttggac aatgctgcaa cgactcctat gtcagcagtt
     6301 gctatttcag ctatgaccaa ggttatgcaa gaaacccacg gaaatccttc tagtattcat
     6361 ggtcatggtc gtcaagctgg caaactcttg cgagaagccc gtcaggaact agcccagtta
     6421 ctaaggacaa aacctcaaca tatctttttc acttctggtg ggactgaagg caataatact
     6481 accatcattg gctactgtct tcgtcaccaa gaacaaggaa aacatatcat cacaactgcc
     6541 atcgagcacc atgctgtcct tgaaacaatt gattacttgg ttcaacactt tgggtttgaa
     6601 gcaaccatta tccagccaga aaatcaagaa atcacagccc agcaaattca aaaggcttta
     6661 cgtgacgata cgattttggt ttctaccatg tttaccaata atgagacagg aaacctactg
     6721 cccatcgctg aaattggcca aatactcaag caacaccctg ctgcctatca tgttgatgca
     6781 gttcaggcta ttggtaaaat cccaattcat tcagaagaat tgggcattga ttttctcact
     6841 gcttctgccc acaaattcca tggtcctaag ggaatcggtt ttctctacgc atctagcatg
     6901 gactttgatt cctatctaca tggcggagac caggaacaga aaaaacgtgc aggaactgaa
     6961 aatctgcctg ctatcgtagg catggttgca gccctaaaag aagacctaga aaaacaagaa
     7021 gaacattttc aacatgtaca aaatctagaa actgcctttc tggcagagct ggagggcatt
     7081 cagtattact tgaatagagg aaaacatcat ctcccttatg ttctcaatat tggatttcct
     7141 ggtcagaaaa atgacctctt actccttcgg ctagatttag ctggaatttc aatctctact
     7201 ggctcagcct gtactgcagg cgttgtccaa tccagccatg ttcttgaagc catgtatggc
     7261 gcaaattcag aacgcttgaa ggaatccctt cgcatcagtt tgtcgccaca aaataccgtt
     7321 gaagacctac aaaccctcgc aaaaacctta aaagaaatta tcggaggtta gccatatggc
     7381 atttgaaaaa atcattcagt taaaaaattg tcgttacgat tacactctta gcccttctgt
     7441 taaaaaattc accctcaaag ataacacctt ttttgaaact aaggttggta actatgaact
     7501 gactcgcctt ttggaaaaag tgccaaacag cggtgaaggc ttccaactca aaatcatcat
     7561 taacaaggaa gttacagggg ctaaaatcaa tatcactgat aagtttggcc ttcgtctagt
     7621 tgatattttc aaatcagaag accaccatat tcatcaggaa aaattctact tcctcatgga
     7681 tagcttggta gaacgtggtg tctttacaaa atcggaaaga tagagccaaa atgtttgaac
     7741 tgacctataa ggactgctat catgtagagc gtactctcaa gtatgaggat catgaggctc
     7801 tcatgttgac tttgtcagga tgtgtaacct taccagatac actttatgtg acttctctga
     7861 cttttagggg ccaaaaagtt tatcagggtc tggtcggaga cctctaccgt tttctatctc
     7921 atgcagattt tttacatcaa aactaagatt tttcttagtt ttttcttatt tttgttgatt
     7981 ttttcacaat gtttctataa aatagaagaa tagaaaggtt gtgattttgt gaaagataaa
     8041 cagtttgcta ttccaaaagc tacagcaaaa agactctctc tctactatcg aatttttaag
     8101 agatttcatg cagaaaagat tgaacgtgcc aactctaagc aaattgcaga ggctatcggt
     8161 attgattcag cgaccgtacg tcgtgatttt tcctattttg gtgaacttgg tcgtcgtggt
     8221 tttggatatg atgtcaaaaa actaatgaca ttttttgccg atttgctcaa tgacaactct
     8281 attaccaatg tcatgctggt tggtattgga aatatgggcc atgcccttct ccactaccgc
     8341 ttccacgaac gtaacaagat gaagattatc atggcctttg acctagatga ccatcctgaa
     8401 gtcggtaccc aaactcctga cgggattccc atttacggaa tttctcagat caaggataaa
     8461 atcaaggatg ctgatgtgaa gactgctatc ctaactgttc ccagcgtcaa gtcacaagag
     8521 gttgctaatc tcttggttga tgctggtgtg aaaggaattc tcagtttttc accagtccat
     8581 ctgcatttac caaaagacgt ggtcgttcag tatgtcgatt tgacaagtga actccaaacc
     8641 ctcctctact tcatgcgaaa agaggattag aaagcgaaaa tcattttatg aaaaaaccag
     8701 ttattgggat tacaggaaac gaaaaaactc atccagatga tgacatcatg atgagctacg
     8761 cagcaaaagg ctttgttgaa ggcgttaaag atgctggagg gattcccatc atcctaccga
     8821 ttggtgatca agaaatggcc tgccactata tcagtttgat tgacaagctc atcttgacag
     8881 gtgggcaaaa tgtcgatcca aaattctatg gcgaacccaa aaccattgat agcgatgact
     8941 atcaccttca aagagatatc ttcgaactgg ccctcatcaa ggaagctatt aaacagaaaa
     9001 agcccatttt ctctgtctgc cgtggtaccc aactctttaa cgttgccatg ggtggaactt
     9061 tgtaccaaga tatcgaagac cattggcagg attcttctgt tgagtacaca actcaacgct
     9121 tggtgacaga accagatacc gttctccaag aaatctatgg agaaatctct catatcaact
     9181 ccttccacca ccagagcatc aaggacttag caccaaattt aaaagttgtg gctcatgatc
     9241 ctaaagatgg tatcattgag gctgtcatga gtacggatga tgtcgccttt ctcggtgtcc
     9301 aatggcatcc agaacttctt tttgaaaatc gtcccaaaga taaaaaactc tttgactatg
     9361 tcgttaatga actttagatt aaatctgtct tttcacgata actaaagtaa ttagaatgag
     9421 agacaatcaa atggtccaag agaacaatcc ccatcagttc gcaggcttct ttaacaagtt
     9481 tagtgacatg atcatcattt tggctaggcg ctaccgctcc tgaaggatga ttgtggacca
     9541 agataagaga agtcgccata tgcttgattg catagtgcag aatctctcgc ggttcagcga
     9601 tactacgagt tacagaaccg ataaaaatgg tctgctgatg gatgatttga ttttgagtat
     9661 tgagatagag tgccaccagg tgctcttgtt ttttatcccc taattcctgc tgcatcttct
     9721 tggccaactt ttgactgctg agaatacttt ccatttcaag agtctcgtgt ttgtgaatac
     9781 gatgccccag ttcaatcata gcttgtaatt ctatggcctt aacacgccca ataccagaca
     9841 aactctgcaa ttcctgcagg gtcatttttt tcaaatccgt taggcttgaa agattgttca
     9901 agactttttg ggcaatttca aaaacgctag cttgacgtgt tcctgtcctg agtaaaatag
     9961 ctagcaactc ttggttacta agcgcttcaa ctccttcctt ggccagcctt tctcttggta
    10021 atagtgaatc ttcttggaat gaaatactgt acataaaaat cctcctcact ttattattcg
    10081 tgagaaggat ggaaaattag atttttttct caattggagc cacactggct aaaagttttt
    10141 tcaaacctac ttctgggaaa ttgattttca attcctgcct agcaccgcta cctgaaactt
    10201 ccagaacagt tccctctccc catttcttgt ggagagcaat gtcaccaatg gaccaatttg
    10261 cctcgctaga tgctgatttt gcgccagctg taaattgacc aaatggaaga ccgcttgact
    10321 ggattgattt tggggcagca ccgcgtttac ggtcttgaag agcctgagcc aaactcatac
    10381 cttgaccaaa ggaaatacta ccactgctat atgatgcctt aaagcttgta tttgcaggac
    10441 gagccagacc ttgatactca agcaagtctg aactgatttc gttaataaaa cgagtcggac
    10501 ggttataatt ggtacgacca aaaagcaagc gtgagttggc attggtcaga tagagaattt
    10561 tctctgcacg cgtgatacct acataggcta gacggcgctc ttcttctaat tcatctgtat
    10621 cttcagtcgc acgactaagt ggaaagacat tttcttccat cccaatcaaa aagacaactg
    10681 gaaattcgag acctttggca gcatgcaggg tcatcaaggt cacttctgat gtctcctgac
    10741 tacctgaatc tgtgtcggca atcaaagcca agtcatttaa gaaacgactc agtttgtcca
    10801 gaccagtttc ctcttctgtc acatcagtgg tgtcatcaaa gttcttcgta acagaaagaa
    10861 actcttcgat attttcaacc cgtgccttgc tttctagagt cgcttgggcg ttaagaatat
    10921 cgacataacc tgttttttct aggacggact caaccaactc tgtaatgctt aagtggtcta
    10981 gctgctcccg caaatcaagc atcatattgg caaaatccca gatagattgg gctgccttac
    11041 ccttgatacc agacaacata atattagcag aagcatccag catagacata ttttgcaaat
    11101 ttgcaaaatc acggattttc tcaactgtac ctggaccaat tccacgttta ggctcgttga
    11161 taatacgctc aaaactaata ttgtcactca aattagcaat aaggttgaga taagcaataa
    11221 tatcgcgaat ttccttacgg ctgtagaatt tggttccgcc aaccatggta taaggaatgt
    11281 tagacttgag cagggcttcc tcaattgtac gggactgggc attagtccga tagagaactg
    11341 caaaatcctt atgaaggaag ttttgactgc gactaagttc atcgatggtt ctggctacaa
    11401 atacagcctc atccagctca tcatcggcac gatagtaaac gatttgctcc ccatcagcgt
    11461 tttgagtcca gagattttta ggacggcgat ttttattgtt tttaataacc tcgttggccg
    11521 cttggagaat ggttttggtt gagcggtaat tttcctccaa caaaacaacc ttggctttgg
    11581 ggtaatcctt ttcaaagtcc aagatattct gcatatcagc accacgccaa ccgtagatag
    11641 actggtccgc atccccaacc acacagatat ttttaaaacg ggaagccaag agtttgacca
    11701 attggtactg agcgtggttg gtatcttggt actcatcaac gtggatgtat tggaattttt
    11761 gctggtagta ggttaaaaca tcaggatttt gatcaaagag acgcaaggtc agcataatca
    11821 aatcatcaaa gtcaacggat tcagactgac gaagttcttt ttgataggct gtataacact
    11881 gggccacaat ttgcgtatac atatcgccag cttgggcagc ataagcaaca tcatcaatca
    11941 aatcattctt agcattggaa atggtcccca aaatagttcg ttcattccat tttttaggat
    12001 ccaagttcaa ctgtttgaga atacgtttca tgagcgttcg ctgttcacca ggatccacaa
    12061 ttgtaaaatt acgattgtag ccaatatggt ccgcatcgcg acgcaaaata cgcacacaca
    12121 tggagtggaa ggtcgcaatc agacagttct gagtagctgg attgagacta taagcacgct
    12181 ctttcatctc acgcgcagcc ttgttggtaa aggtaatggc caagatattc caaggattga
    12241 ccagcttttc atcaatcaaa taagcgatac ggtgggttaa aacacgagtc tttccagaac
    12301 cagcccctgc catgattagc aagggacctt ctgtcgtttg caccgcctca gcctgacggt
    12361 cattcattcc atttaataat gcgttcatct tctcttcctt actcttgaag tcaatatttc
    12421 tattatatca gaaatcaggg aaaatagaaa ctttacgggg agtagcaaaa tatagtggat
    12481 tgaaactaga atactacact gtgggtttct aaaacactcg acttttcacc caattttttc
    12541 ataaactagc tcaatacctc aatagacttc ctgcaaaact agaatcctag ttcatgattg
    12601 ataataccag caataaaatt cattcgtaat ccgaagcgtt tacgatgatt tcgataagtt
    12661 gttgaaaaca ttttaaacgt ttttactttg gcaaagatgt tctcaacctt gcttctctcc
    12721 ttagatagcg catggttata agccttatct tcaactgtta gcggcttgag tttgctggat
    12781 ttacgtggag tttgtgcttg aggatatatt ttcatgagcc cttgataacc actgtcagcc
    12841 aagattttac cagcttgtcc gatatttctg cgactcattt tgaacaactt catatcatga
    12901 caatagttca cagtgatatc caaagaaaca attcttcctt gacttgtgac aatcgcttga
    12961 gccttcatag cgtgaaattt ctttttacca gaataattgg ctagttgatt tttttagggc
    13021 gattggtttt tacttccgtc gcatcaatca ttaccgtgtc ctcagaactg agaggagttc
    13081 ttgaaatcgt aaaaccactt tgaacaagag ttacttcaac ccattggctc cgacggatta
    13141 agttgctttc gtgaatacca agatcagccg caatttgttc ataagttcga tattctcgca
    13201 catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt cttccacctt
    13261 ttgcatgttt aagttgataa gctgttttta atacagctaa catctcttca aaagtggtac
    13321 gctgaacatc aacaagacgc ttaaatcgtg catcagttag ttgtttactt gcttcatcat
    13381 tcatagaact actataccat gttttgtttc gcaggaagta taatataaaa aaataaattt
    13441 aagattggca atacgaacgt taaacagaat tccatttctc tttttagaat caaaacgaca
    13501 atattgtgga atctctacag gaacaataga ctgcgacact aaaatatcct cccttagttt
    13561 tactttacta atagtatata ggaggagagc cctgaatcct agaccctttg ttatgatgcg
    13621 cttacaaaca gagttggaaa aaatcttaaa agcagaaaaa cgcatgatat cagcccctaa
    13681 cacttgatac aatgcgtttt attatgaaaa gatctactgg attttttatc aaaataaact
    13741 tccagtagtc ttttcacttt ttattaataa gttccttctt caccttggct agtcaagata
    13801 acaggtccat ctttcgtaat gacaaattgg tgttcatact gacatgacaa tccaccgtca
    13861 atggtcttat gcgcccaacc agttttcata tctgtatcaa tttcccaatc gcctgtattg
    13921 atcattggtt caatggttaa gaccattcct tcacgaagac ggagtccacg acctgcaata
    13981 ccatagttag gaaccattgg ttcttcgtgc atagttgggc caacaccatg accaaccaaa
    14041 tcacgcacta caccgtaacc acgactttca gcgtattctt gaatagccgc accgatatca
    14101 ccgatacgat ttccaacaac agcttgctca atacccttgt acatagcttc tttggttaca
    14161 tccatcaagt ttttgacttc ttcggacggt gtaccaacag cataagccca acatgagtct
    14221 gctaaaccac cagaatagct ctgagtatat tttttcattt gttcaacatt gttgaagttt
    14281 aattttgaga cattcaggtc agatttagca atgggacctc ccaaaaccat atcaactttg
    14341 agcaaatcac catctttcaa gatataatga cgagggaaag cgtgagccac ttcatcgtta
    14401 agagagcaac aggtagcata aggatagtcc atcatggcac cgtcaacccc aatctgaagt
    14461 ggaaggaaat tttcttcttt acaacgacgg cggacatatt cttcaacttc ccacatatct
    14521 acgcctggct taatcaaatc acgtaagcct atatgaatac ttgctagaaa atcaccagcc
    14581 ttgtccatag cttcgatttc acgagctgat tttaatgtta tcatcttttc tcctagtttc
    14641 taattaattt taacagtcac atttgctttt gaaacaatct ggtgaccatg ataaatatcg
    14701 taatcaatta tagctgaccg tctcgtatga tgaataatcc gtgcctgaat gcgcaatata
    14761 tcatctatct gaacagcctg caaaaagtag atcagcatct gctcgataat gagattgcga
    14821 ccactattaa caactaaatc ttgggtcatg tgggtcagaa tttctgccaa tacaccatta
    14881 gccaaaactc catttttttc tagcataaag ggttccactg taatgactac ttcatcatgg
    14941 tgataagaga gcttttgtcc aatctgctca gaaaaagttg gtagagccga aacttgggaa
    15001 cggctcatct tctccatgac atctcgtcgc gtcacaacgc caagcaaagt ttgattgctt
    15061 cgaacaactg gtaccatttc aaagtcttct gcgatcatcc gttgactcac attggcaata
    15121 tttgtcgata atccaaccaa aaatagacta cgagacataa ccttatcaat tgtcgtgctt
    15181 ggtgatttat caccagcgtc tctcatggtt acaacgccaa caacgacctg atgttgattg
    15241 ataacaggga aacggctgct acgattctta cgaaccaagt ccaaataatc tttaactgta
    15301 tctgtctctc tcagaaaacc atactcatga ctagggcgat aaagtttctc aactgtcaga
    15361 atatcagtct tgatttggac atttgacaag gctttattga tcatggtcgc gacggtaaag
    15421 gtatcatgct tacttcttag aacaggaatc cctttttgat tggccagttt aagcacatca
    15481 tcatgaacct gaaatccccc tgtaaccaga actgcatttt cattttccaa ggctagcaac
    15541 tgaatacggg ttcggtctcc gacaatcaag agccccccat catgaaggta agacaagata
    15601 ttttgttcag tcatggcacc aattgaaaac ttactaaatt ctctctctaa accttcttgc
    15661 ccagccagaa cctcagaaga agtcacttct gcaatttcag caaacgttaa tctctctata
    15721 gcaactttct gggatttaac acgaattgtt ccacttctag gacgggtctc cacaattcca
    15781 cggttttcag cttctttaat agcccgatag gctgttccat cactaactcc tagatgattc
    15841 gaaatgctac gaacactgac ccttttacct actggtaatt cctccaaata gcttagaatt
    15901 tcctgatgct tactcattga actctccttt tacataccga aattcaagat aatcccgcat
    15961 ttttcttgtg taacgatcac ttcccttaaa ctgacggaac aaactaaatc cagacttaag
    16021 agcaactctt tggctagctt cattttcaag gtgggtaatg atagataatt gttttaagcc
    16081 aaattcctca aaagaaagct gacaaatttt tctaacaacc tctgtcataa atccttgcga
    16141 ccaagcatct tttctcaaaa aatagccaag ctcagcttct tttttgattt catctaactt
    16201 ctcaaattta atagaaccaa tcatttgttg atttttctgg tcacaaattg cccacactcc
    16261 caaaggggac ttcataaagt aattggccag tgcatattga ctttcttcca gacttgcctg
    16321 cgttgggaaa ataaattgaa gattttctgg atttgaagct atctcgcgga agtcctgact
    16381 atcactaaaa aagaaaggac gcaaatacaa gcgatccgtt tcaaaaaaag aaaacattgc
    16441 taatttggtc caaatattca taaacacctc tacggtttaa tcctcaacaa gtctaatatc
    16501 cgctcctaaa ttacgtaatt tttcgataat atcagaataa ccacgtaaga taaactcgat
    16561 attggtaatt tcagttttac cttcagccat aagcccagca atgactagtg cagccccagc
    16621 tcttaagtcg gtcgctttaa cactggcccc acgtaaatca cgtccacccg tgtacaaaat
    16681 atgaccattt gttgtcgaaa tatccgcatc catctttgct agttcaaaaa catgatttac
    16741 acgtttttcg taaatcgtat cgacaattgt accacgacca ttcgctctta gtaaaagagg
    16801 ggtaagcggt tgttgcaaat cagttgcaaa gcctgggtaa ggagctgtct taatattgat
    16861 tgctttcaaa ttagactgtt cctcgacaaa aatgctgtct tcagatacag tcattctcac
    16921 tcccatttct tccaacttag caataaaccc ttccaggtgt tcgtaaagaa cattatttat
    16981 acgaattcct ttaccaactg cagcagctaa agatatatat gttccagctt caatgcggtc
    17041 tggaatcacc tgatgacgtg tcccatgtaa tctttcaaca ccatcaataa tgatgatatt
    17101 agttcctgcc ccacggatat gggcacccat attattcaag agagtagcta catcaataat
    17161 ctcaggttca cgggctgcat tttcaataat agtacgacca tttgctttaa ccgcagcaat
    17221 catcgtatta atcgttgctc ccacactaac cgtatccatg taaatacttg caccatgaag
    17281 tcctgtatct ttagcagata acttcatgtt atctccctcg tagctagcag tggcacccat
    17341 agcttcaaac gccttaaggt gtaagtcaat cggacgagga ccaagatcac atcctcccgg
    17401 tagaccaact gtcgcttcac caaaacggcc taagaggctc ccataaaaat agtaagatgc
    17461 acgaagactg ttaattttac cataaggcat tggaatattt tgaacacctc ttggatcaat
    17521 ctccaagaca tcgtcataac gcttaacagt agctcccatc aattccatga tttcgacaag
    17581 actggctaca tccgaaatat ctggaacaca atccaaagtc accacatcat cagccaagat
    17641 aatagctgga attaaggcca caacactatt tttagcacca ctaatagtaa tttcaccttg
    17701 cagtggtaat ccaccattga taacaatttt tctcattcta agttttcaat actctttcaa
    17761 gatttctaat aaggtcttca aaataaagta tatcataaat ttatcctttt ttccatcctt
    17821 ttcaatttta ttggataaat cagagttgac gagttagtaa ctgaattact aatactcaat
    17881 aaaaatcaaa ga
//
LOCUS       DAVBOH010000044        16933 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOH010000044 DAVBOH010000000
VERSION     DAVBOH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.044"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ873_001654"
     CDS             <1..211
                     /locus_tag="VQ873_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107882.1"
                     /translation="PRKSSKLKPLIAEDKAYNHALSKDRSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLSAGIINHELGF"
     gene            260..724
                     /locus_tag="VQ873_001655"
     CDS             260..724
                     /locus_tag="VQ873_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3107883.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            882..1307
                     /gene="lacA"
                     /locus_tag="VQ873_001656"
     CDS             882..1307
                     /gene="lacA"
                     /locus_tag="VQ873_001656"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3107884.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1338..1853
                     /gene="lacB"
                     /locus_tag="VQ873_001657"
     CDS             1338..1853
                     /gene="lacB"
                     /locus_tag="VQ873_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3107885.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1864..2793
                     /locus_tag="VQ873_001658"
     CDS             1864..2793
                     /locus_tag="VQ873_001658"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3107886.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2795..3775
                     /gene="lacD"
                     /locus_tag="VQ873_001659"
     CDS             2795..3775
                     /gene="lacD"
                     /locus_tag="VQ873_001659"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3107887.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4009..4845
                     /locus_tag="VQ873_001660"
     CDS             4009..4845
                     /locus_tag="VQ873_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3107888.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4881..5198
                     /locus_tag="VQ873_001661"
     CDS             4881..5198
                     /locus_tag="VQ873_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3107889.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5198..6889
                     /locus_tag="VQ873_001662"
     CDS             5198..6889
                     /locus_tag="VQ873_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3107890.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7104..8510
                     /gene="lacG"
                     /locus_tag="VQ873_001663"
     CDS             7104..8510
                     /gene="lacG"
                     /locus_tag="VQ873_001663"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3107891.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8600..8812
                     /locus_tag="VQ873_001664"
     CDS             8600..8812
                     /locus_tag="VQ873_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3107892.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9091..9852)
                     /locus_tag="VQ873_001665"
     CDS             complement(9091..9852)
                     /locus_tag="VQ873_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3107893.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ873_001666"
     CDS             complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ873_001666"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3107894.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ873_001667"
     CDS             complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ873_001667"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3107895.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ873_001668"
     CDS             complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ873_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3107896.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13993..14256
                     /locus_tag="VQ873_001669"
     CDS             13993..14256
                     /locus_tag="VQ873_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3107897.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ873_001670"
     CDS             14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ873_001670"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3107898.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ873_001671"
     CDS             16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ873_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3107899.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5282 a         3057 c         3509 g         5085 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc
       61 gctatctaag gatagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgagtgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata aagaaactag
      241 caaggtcagg ccttacttta ttggtggaca tccaggattt aattgtcttc tacttgatga
      301 tgaagtctat gaagattatt atctagagtt tgagaaagaa gagatttgct ctgttccacg
      361 tcctttccca gaaacaggta tgttggattt ccaagataga agtccatggc tagagggaca
      421 aaaagaaata gatcttagtt atgatctttt cagcacagat gcagtgactt tggatgaatt
      481 gcaatctcga acaattgccc ttcgttctct taaacatgat aagggattga aagtgcattt
      541 tgcagaattt ccaaacctca tcatctggtc aactttgaac aagggacctt tcattacctt
      601 tgaaccatgg tctggcttgt caacattcct tgaagaagga gatcatttag aagataagaa
      661 gaatgtttgt ctcttagaag ccaatcaggt tgaagaatta gggtttgaga tagaagtttt
      721 ataaaaaaag taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa
      781 tagtagtata ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact
      841 gctggaatcc agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg
      901 cagatgctgc aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact
      961 tccaccttgt ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg
     1021 ctgcagaagt aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg
     1081 gtccatttat ggttgcaact aagatcaaag gaatggttgc tgcagaagta tctgacgaac
     1141 gttcagctta tatgactcgt ggccacaaca actcacgtat gatcactatg ggggcacaac
     1201 ttgttggtga tgaattggct aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg
     1261 gtggtcgtca ccaaatccgg gttgacatgt tgaacaaaat gtgctaatta gattatagta
     1321 agaaaggtaa gttaaaaatg agaattgcaa ttggatgtga ccacatcgta acagatgaaa
     1381 aaatggcggt ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacct
     1441 atgaccatac acgtactcac tacccaatct ttggtaaaaa agtaggggaa gcagtaacta
     1501 gtggtcaagc tgatctcggg gtatgtatct gtggtactgg tgttggtatc aacaacgctg
     1561 taaataaagt tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg
     1621 ctaaagaaca attgaacgcc aacgttatcg gttttggtgg taagattact ggtgaattgc
     1681 ttatgtgtga tatcatcgaa gctttcattc atgctgaata caaaccatct gaagaaaaca
     1741 aaaaattgat tgcgaaaatt gaacaccttg aaagtcacaa tgctcaacaa acagacgcaa
     1801 acttcttcac tgaattcctt gaaaaatggg atcgtggaga ataccacgac taagaggtaa
     1861 cctatgattt taacagttac aatgaaccca tccattgata tttcctatcc cttggatgag
     1921 ttgaagattg atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga
     1981 ctcaatgtta cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg
     2041 ggtggcaaac ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc
     2101 ttctcaattc agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca
     2161 gaagttcttg aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat
     2221 ttcaaaaaac tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc
     2281 cttccagttg attactgtgc gagcttggta gaacttgcta atcaagctgg caagcctgta
     2341 gtcttggact gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca
     2401 gtcatcaaac caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat
     2461 ttggatgaat taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc
     2521 gtttcacttg gtgccaacgg tacttttacc aaacatggtg acactttcta caaggtagat
     2581 attcctagaa ttcaggcggt aaatcctgtt ggatctggag actctactgt ggcaggaatt
     2641 tcttcaggac ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt
     2701 ggtatgctca atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagct
     2761 ctatatgatc aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt
     2821 acgcttagaa aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg
     2881 tggtgctttg aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat
     2941 ggaagaactt aaagttttgg tagcagatga attgactaaa tacgcttcat ctatgcttct
     3001 tgaccctgag tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct
     3061 tgcttatgaa aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga
     3121 tgtttggtct gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta
     3181 ctatgatgta gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat
     3241 cggttctgag tgtgtggctg aagatatccc attcttcctt gaaatccttg cttacgatga
     3301 aaaaattgca gacgcaggtt ctgtagaata cgctaaagta aaaccacaca aagttatcgg
     3361 tgctatgaaa gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc
     3421 tgttaacatt aaatatgttg aaggcttcgc tgagggtgaa gtggtttaca cacgtgaaga
     3481 agcagcagcc ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag
     3541 tgctggtgta tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc
     3601 aaactttaac ggagttcttt gtggccgtgc tacatgggca gggtcagttg aagcttacat
     3661 caaagatggt gaagcagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga
     3721 tgagctcaat aaagttcttc aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag
     3781 tcctcctagt ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt
     3841 acaaaataac ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta
     3901 agtaatatta ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt
     3961 ggtcattttt tgtactcata tacctttaaa atataaaagg aggttgacat gtatcgaatt
     4021 ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt
     4081 gtaattggta aggggattgc attcggaaag aagaaggggg atttgattgc tgaaaatcag
     4141 gttgagaaaa tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc
     4201 aaagatgttc cgcttgattt tatcacagtg acctatgaaa ttattgataa gctatcaaag
     4261 aaatatcatt atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt
     4321 tcttatcaag ctctaactca aggaaggtac aaggatagta atctgccaga tatttccgct
     4381 aagtatcctg tcgcttttca aatcgcaaat gaagcttttg aaatttaccg tcagaagcta
     4441 gcagatcatt ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa
     4501 ggtgaaaatg aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat
     4561 gttgaagaag ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat
     4621 gatcgcttta tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat
     4681 aaccaatcac ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag
     4741 attggttcca agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt
     4801 gaacgagttt atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac
     4861 tatataagga gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg
     4921 tagcctatgc tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg
     4981 gtgattttga aaaagcggac gctctggtag aggaagctgg tagctgtatt gcagaggctc
     5041 accacgcgca aacaagtcta ttgactaagg aagcttctgg tgaggactta gcgtatagtg
     5101 tgaccatgat gcatggtcaa gatcacttga tgacaactat cttgttaaaa gacctaatgc
     5161 accatttaat tgaactttac aagagaggag ttaaataatg aataaactaa ttgcatttat
     5221 cgagaaagga aagcctttct ttgaaaaact atctcgtaat atctatcttc gtgctattcg
     5281 tgatggtttc attgcaggta tgcctgttat tctcttctca agtatcttta tcttgattgc
     5341 ctttgtacca aactcatggg gctttaaatg gtctgatgaa gttgtagcct ttctgatgaa
     5401 accttatagc tattctatgg gtattctggc tctcttggta gctggtacaa cagctaagtc
     5461 attgactgac tcagtaaacc ggagcatgga aaaaaccaat caaatcaact atatgtcaac
     5521 attgttggca gcaattgttg gtttgttgat gttggcagct gatcctatcg aaagtggtct
     5581 agctactgga ttcttgggaa caaaaggttt gctttcagcc ttccttgctg ccttcgttac
     5641 tgtagccatc tataaggtct gtgttaagaa caacgtcact attcgtatgc ctgacgaagt
     5701 tccaccaaat atctcacaag tctttaaaga tgtgattcca ttcactctat cagtggtttc
     5761 tctttatgct cttgatttac tagctcgtca ttttgttggt tctagtgtgg cagaatcaat
     5821 cggtaaattc ttcgcaccac tcttctcagc agcagacgga taccttggta ttaccattat
     5881 ctttggtgcc tttgccttct tctggtttgt tgggattcat ggtccatcta tcgttgaacc
     5941 tgctatcgca gcgattacct atgcaaatgc tgaagtcaac ttgaaccttc tccaacaagg
     6001 gatgcatgca gacaagattc ttacttctgg tacacaaatg tttatcgtta ccatgggtgg
     6061 tacaggtgcg acattggtcg ttccatttat gttcatgtgg ttgacaaaat cgaaacgtaa
     6121 ccgtgcaatc ggacgtgctt cagtagttcc taccttcttc ggtgtaaatg aaccaatctt
     6181 gtttggtgca cctcttgttt tgaatccaat cttcttcatt ccatttatct ttgctccaat
     6241 tgcaaacgta tggattttca aattctttat tgaaactctt ggaatgaact cattcactgc
     6301 taatctacca tggacaactc cagctccact aggtctagtt cttggaacta acttccaagt
     6361 gctatcattc attcttgctg cccttctaat tgtggttgac gtagttattt attacccatt
     6421 ccttaaagtc tatgatgaac aaattcttga agaagaacgt tcaggtaagt ctaatgatga
     6481 attgaaagaa aaagttgctg caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa
     6541 agcgggtgtc gatgcagcac aaaataccat cactgaagaa acaaatgtcc tcgttctctg
     6601 tgctggtgga ggtacaagtg gactccttgc aaatgctttg aataaggcag cagcagaata
     6661 caatgtccct gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa tgttgccaga
     6721 gtttgatttg gttatccttg ctcctcaagt tgcttcaaac tttgaagata tgaaggcaga
     6781 aacagataag ctcggtatta aacttgctaa gacagaaggc gctcaataca tcaaattaac
     6841 tcgtgatgga aaaggtgccc tagcattcgt acaagagcaa ttcgattaag gctaggaact
     6901 gtgaaacagt ctcccatcgt tacggaaatc gctatggcga atttcctaat cgccttatta
     6961 attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcagt gacttggtac
     7021 aagaagtgag atggagaagc atggctcact gactcctctc ctctcacttt tactttattt
     7081 aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt attttcggtg
     7141 gcgcaacagc tgcttatcaa gcagaaggtg ctacacatac tgatggaaaa ggaccagttg
     7201 cttgggataa atatcttgag gataactact ggtacactgc cgaaccagct agtgattttt
     7261 acaatcgata tccagttgac ctcaagctag cagaagagta tggtgtcaat ggtattcgaa
     7321 tttctattgc ctggtcacgt attttcccga ctggttacgg ccaagtaaat gttaaaggtg
     7381 ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgag ccctttgtaa
     7441 ctcttcatca ctttgacacg ccagaagctc tccattcaaa tggagacttc ttaaaccgtg
     7501 aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt ccagaagtaa
     7561 actattggac aacctttaat gaaattggac caatcggtga tggtcaatat ttggttggga
     7621 aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac cacaatatga
     7681 tggtgtctca tgcgcgtgca gtcaagctat ataaagataa aggctataaa ggggaaattg
     7741 gtgttgttca cgctctgcca accaagtatc ctttggatcc taaaaatcca gcagatgttc
     7801 gtgcagctga gttggaagat atcatccaca ataaattcat cttagacgca acttatctag
     7861 gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc aatggtggta
     7921 gtttggatct tcgtgaagaa gattttacaa cattagaagc tgcaaaagac ttgaatgatt
     7981 tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga gaaactgaaa
     8041 ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa ggtgttggtc
     8101 gtcgtgtagc tcctgactat gtaccacgca cggattggga ttggattatc taccctcaag
     8161 gtttgtatga ccaaatcata cgtgtgaaga aagattatcc taactacaag aagatttaca
     8221 tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt tacgatgatg
     8281 gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcgatt gcagatggag
     8341 ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg tcaaacggtt
     8401 atgaaaaacg ttacggtctc ttctacgtag attttgaaac tcaagaacgt tatcctaaga
     8461 aatcagctca ctggtataag aaagtagcgg aaactcagat tatagactag tagaattagt
     8521 cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc caatctattt
     8581 atgaaaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     8641 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat ggatttgtca
     8701 ttcagatgat gagctggaag aatttaaaaa tctattttta aattttatca atcctgaaga
     8761 atgggatact atctcctttg attcagattt tatgccgttt caacaatcgt aaccaatttc
     8821 tcaaaaaagt taaatcttat atttagtact ctgtaaaact cttatctaat cacgttgctt
     8881 atactcaatg aaaatcaaag agcaacttta aactaggaag cgagtcgcag atttctcaat
     8941 gcatagcttt gaggaattgg gcaaaaagtc tttgatatag aaaaacgcat agtatcaggt
     9001 gtttcaacac ctgatattat gcgttttatt gtgggaagat ttactttttt tcttctgaaa
     9061 ttgagttgtt acccaggctc tttcagttta ttaaggcttg atgactttaa tgtgtttaga
     9121 tagcttaaaa aggattgaat cacttagttt agaatctgaa acaatagtat caagatttga
     9181 tacattataa aaagtataaa aatcaaactt attgaacttg ctatgatctg cgagtaaata
     9241 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
     9301 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
     9361 agagagattt tgtagggtca atgtaccaac aaaagcacct gtaatatcgc gataatttcc
     9421 acctattaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
     9481 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
     9541 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
     9601 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
     9661 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
     9721 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
     9781 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
     9841 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac aaactcatca
     9901 ttcaaataca aaaacaacaa aatgaaacaa aaacaaaaat atcgaagttt gttttcaaaa
     9961 ctttcgatat ttttgttggg ttataacttt gatgtttcta gtttactttt tgatgattga
    10021 gagtgatgga gaattagtct aaaccgtagt tatagtcatc gtcttgcatg gcttcaactt
    10081 cgccaagaag gtaaccattt ccgacttgag agaagaagtc atggttggaa gttcctgttg
    10141 aaataccgtt cataacgatt gggttgacat cttcagctga atctgggaaa agtggatctt
    10201 gtcccatgtt catgagagct ttattggcat tgtagcgaag gaaggtttta acctcttcag
    10261 tccaaccaac accgtcataa agactctctg tgtagccttc ttcattttca taaagagtat
    10321 agagtaggtc gtacatccat tctttgagtt tttcttgctc ttcttcaggc aattcattga
    10381 aaccaagttg gaatttgtaa ccaatgtagg ttccgtgaac agactcgtca cgaataatca
    10441 atttaatgat ttctgcaacg ttggctagtt tgttgttacc gagatagtag aggggagtga
    10501 agaaaccaga gtagaagagg aaggtttcga ggaagacgct ggcaactttc ttttcaagtg
    10561 ggctgccgtt taggtagatt tcgttgacaa tctcagcctt cttttgtagg taaggattgg
    10621 tattggtcca ttcgaaaatt tcttcaatct cagccttagt attcaaggta gaaaagattg
    10681 atgagtaaga tttagcgtgg acagattcca taaattggat gttattgaaa acagcttcct
    10741 catgtggtgt acggatgtct gcgcgaaggg cttgaacccc agtttcagat tgcatagtgt
    10801 caagaagggt taaaccacca aaaacttttc cgaccaagtc tttctctttg ttagatagct
    10861 ttctccagtc atccaagtcg tttgataagg gaatacgtgt atcgagccaa aattgctccg
    10921 tcagtttttc ccaagttgat ttgtcgatga catcttcgat ggcattccag ttaatggctt
    10981 tgtagtaagt ttccatttaa aatctctttc tgtgtttagt attgcgaact cacaattatt
    11041 tctactttac cataattcta taggagtatc gcacaaaaag tcggaagccc gacttttaaa
    11101 atgttacata aattatgtta tgacatagta gatttgattt tatcagtgct gcttagggaa
    11161 aaataatgtt tctatgctag aaactaaatc acacagcttt cacattggtt ggcgccgact
    11221 tctccaccgt catctgtaaa ggtacggacg tagtagatag acttgattcc cttgttaaag
    11281 gcatagttac gaaggatgga caaatcacgt gtcgtttgtt tattttccct cttccattcg
    11341 taaaggcctt ttggaatgtc actgcgcatg aagagggtga gtgaaagtcc ttgatccacg
    11401 tgttcagtcg cagcagcgta aacatcgatg actttacgca tatccatatc gtaggcagaa
    11461 gtgtagtaag gaatggtttc tgtagacaag ccagcagcag ggtagtagat tttaccaatt
    11521 ttcttctctt ggcgttcttc gatacgttgc gtaatcgggt ggatagaagc agaaacgtcg
    11581 ttgatatagc tgatagaacc atttggcgct acagcaaggc gattttggtg gtaaagacca
    11641 tcttcttgaa ccttgtcgcg aagttcagcc caatcagcaa caccagggat aaaaacattt
    11701 ttgaagagtt ctttaacacg gtctgatgtt ggaacaaatt caccagttac atacttgtca
    11761 aagtaacttc cgttagcata gtctgatttt tcaaagttgt ggaaggtaat accacgttca
    11821 cgcgcaatat tgtttgactc taccaaggtc cagtagttca taagcataaa gtagatgctt
    11881 gtaaattcaa cagactcagg tgaaccatat tcaatgagtt gttgggcaag gtagctgtgc
    11941 agtcccatgg caccgagacc aaaggtgtgg gcttggctat ttccatggtc aatcgttggt
    12001 acagctacga tatgtgaact atctgtaacg aaagtaaggg cacgaaccat agcacggata
    12061 gaacgaccaa aatcaggtga agtcatcatg ttaaccacgt tggttgaacc cagattacat
    12121 gaaacatctg ttcccatttg aaggaattct tgagcatcgt tgatcaagct tggttcttga
    12181 acttgaagaa tctcagaaca caagttactc atgataatct ttccatcaac aggatttgca
    12241 cggttagccg tatcgatgtt gactacataa ggatagccag actcttgttg caatttagag
    12301 atttcagttt ccaaatcccg cgccttgatt tttgtcttgc gaatatttgg atttgcgacc
    12361 aattcatcgt atttttcagt aatgtcgatg taattgaatg gcacaccgta ttctttttct
    12421 acagagtaag ggctgaagag gtacatttct tcatttttac gagccaattc gtagaattta
    12481 tcaggtacta caacaccaag tgatagagtc ttgacacgta ctttttcatc agcgttttct
    12541 ttcttagttg aaaggaaagc gatgatatct gggtgaaaga cgttgaggta gacaacacca
    12601 gcaccttgac gttgccccaa ttggttggag taagagaagc tgtcttcaaa aagcttcata
    12661 acaggaacga cacctgaagc agctccttca tagcctttga taggtgcacc agcttcacga
    12721 aggttgctga gggtaattcc cacaccacca ccaatacgtg aaagttgaag agctgagttg
    12781 atagaacgtc cgatagagtt catatcatcc gtcacttgga ttaggaaaca agataccaac
    12841 tccccacgac gagcacgtcc agcattcaag aaggaaggag tagcaggttg gtagcgttgg
    12901 tggatgattt cattggcaat atcgattgca acagcttcat tcccatcagc gaaataaagg
    12961 gcgttgaaga agacacggtc ttccatattt tcaagatagt attcaccgtc attagtcttt
    13021 aaggcatatt gattgtaaaa tttataagct gccatgaatg acttgaattg gaagttttgg
    13081 tctttgataa attgagccaa ttcttccaag aactctggac ggtatttctt gataaaggct
    13141 gtttcgatgt agttgtgttc aatgaggtaa ttgattttgt ctttgattga atcaaaaacc
    13201 atagtgtttg gaactacatt ttctttaaag aaagcatcca aggcttcctt atctttatga
    13261 agcatgattt gtccattaac aggacggtta atttcgttat taagacggaa gtaagtcacg
    13321 tcttcaagat gttttaatcc cataaaattt cccttatcta attacaaaag aaaggcttct
    13381 aagttagccc taaaagcagt ttcttctgga tgatgtacta agattatgct aattgtttca
    13441 gttttcctgg ttggaaacct gaaaagactt cagttggtgt ttggataaca ggagctgcgc
    13501 taaaaccgag ctctttaact tgatcgacgt actcaggttg ctcatcaaga ttgatttcac
    13561 gataagagac attattactg tccaagaaac gcttggtcat tttacattgg acacaattgt
    13621 ttttagaata aacggttacc attgtgtaac tcctcttcaa aatttaatac tatcttagta
    13681 tatcagaaaa taaaattttg tcaatgattt gaactaaata tagtggtgtt cttttgttgt
    13741 ttttatatat aaacacaata tatagtgttt gtattgtgaa atagcaatga ttatcctata
    13801 aattgttttt aaagaaacta tatcctgtgt tttgttatct aggatagaag attttcagca
    13861 agttatctga aaggaaattg aaggaaaatc cagaaaatgc ttgaaaaaaa tcctagaaga
    13921 tggtataata ctaaattgta agggttatca catataactc aaaaaaagaa agaacaaaag
    13981 gagagtcaaa ctatggcttc taaagatttc cacgtagtgg cagaaacagg tattcacgca
    14041 cgtccagcaa cattgttggt acaaactgct agcaaatttg cttcagatat cactcttgag
    14101 tacaaaggta aatcagttaa ccttaaatca attatgggtg ttatgagtct tggtgttggt
    14161 caaggtgctg acgtaactat ctcagctgaa ggtgcagatg cagatgacgc tatcgctgca
    14221 atctcagaaa caatggaaaa agaaggattg gcataaggga aatgacagaa atgcttaaag
    14281 gaatcgcagc atctgacggt gttgcagttg caaaagcata tctactcgtt cagccggatt
    14341 tgtcatttga gactattaca gtcgaagata caaacgcaga agaagctcgc cttgatgccg
    14401 ctctacaggc atcacaagac gagctttctg ttattcgcga gaaagcagta ggtacgctcg
    14461 gtgaagaagc agctcaagtt tttgatgctc acttaatggt tcttgctgac ccagaaatga
    14521 tcagccaaat caaggaaact atccgtgcga agaaagtgaa tgcagaagca ggtctgaaag
    14581 aagttacaga tatgtttatc actatctttg aaggcatgga agacaaccca tacatgcaag
    14641 aacgcgcagc ggatatccgc gacgtgacaa aacgtgtatt ggcaaacctt cttggtaaaa
    14701 aattgccaaa cccagcttct atcaatgaag aagtgattgt gattgcgcat gacttgactc
    14761 cttcagatac agctcaattg gacaaaaact ttgtaaaagc ttttgtaacc aacattggtg
    14821 gacgtacaag ccactcagct atcatggcac gtacacttga aattgctgct gtattaggta
    14881 caaacaacat cactgaaatc gttaaagacg gtgacatcct tgctgttaac gggatcactg
    14941 gagaagtgat tatcaaccca acagatgaac aagcggcaga atttaaagca gctggtgaag
    15001 cctatgcgaa acaaaaagct gaatgggcac ttttgaaaga tgctcaaaca gtgactgctg
    15061 acggtaaaca cttcgagttg gctgccaata ttggtactcc aaaagacgtt gaaggtgtta
    15121 acaacaacgg tgcagaagct gttggacttt accgtacaga gttcttgtac atggattctc
    15181 aagacttccc aactgaagat gagcagtatg aagcatacaa ggctgttctt gaaggaatga
    15241 acggtaaacc tgttgtcgtt cgtacaatgg atatcggtgg agataaggaa cttccttact
    15301 tcgatatgcc tcacgaaatg aacccattcc ttggattccg tgctcttcgt atctctatct
    15361 ctgagactgg agatgctatg ttccgcacac aaatccgtgc tcttcttcgt gcgtctgttc
    15421 acggtcaatt gcgtatcatg ttcccaatgg ttgcgctctt gaaagaattc cgtgcagcga
    15481 aagcagtctt tgatgaagaa aaagcaaacc ttcttgctga aggtgttgca gttgcggata
    15541 acattcaagt tggtatcatg atcgagattc ctgcagcggc tatgcttgca gaccaatttg
    15601 ctaaagaagt tgacttcttc tcaattggta caaatgactt gatccaatat acaatggcag
    15661 cagaccgtat gaacgaacaa gtttcatacc tttaccaacc atacaaccca tcaatcctac
    15721 gcttgattaa caatgtgatc aaagcagctc acgctgaagg taaatgggct ggtatgtgtg
    15781 gtgagatggc tggtgaccaa caagctgttc cacttcttgt cggaatgggc ttggatgagt
    15841 tctctatgtc agcaacatct gtacttcgta cacgcagctt gatgaagaaa ctcgacacag
    15901 ctaagatgga agagtacgca aaccgtgccc ttacagaatg ctcaacaatg gaagaagttc
    15961 ttgaacttca aaaagaatac gttaattttg attaatcgaa aagtccctgc aactcagtta
    16021 cagggacttt ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt ataaaaagtc
    16081 caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa atggttcata aaattcttga
    16141 caagttggag atttaggagt aaactattaa ccagttaagt aatagagagg agtttctgca
    16201 atttagaaat gaattgcaac tagaaatatc aaatagaaag agagtttcga tgaaaattaa
    16261 taagaaatac cttgttggtt ctgcggcagc tttgatttta agtgtttgtt cttacgagtt
    16321 gggactgtat caagctagaa cggttaagga aaataatcgt gtttcctata tagatggaaa
    16381 acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat
    16441 caatgctgag caaatcgtca tcaagataac agaccaaggc tatgtcactt cacatggcga
    16501 ccactatcat tattacaatg gtaaggttcc ttatgatgcg attttcagtg aagaattact
    16561 catgaaagat ccaaactata agctaaaaga tgaggatatt gttaatgagg tcaagggtgg
    16621 atatgttatc aaggtagatg gaaaatacta tgtttacctt aaggatgctg cccacgcgga
    16681 taacgtccgt acaaaagagg aaatcaatcg acaaaaacaa gaacatagtc aacatcgtga
    16741 aggtgggact ccaagaaacg atggtgctgt tgccttggca cgttcgcaag gacgctatac
    16801 tacagatgat ggttatatct ttaatgcttc tgatatcata gaggatactg gtgatgctta
    16861 tatcgttcct catggagatc attaccatta cattcctaag aatgagttat cagctagcga
    16921 gttggctgct gca
//
LOCUS       DAVBOH010000045        16447 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOH010000045 DAVBOH010000000
VERSION     DAVBOH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.045"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ873_001672"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ873_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3107900.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ873_001673"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ873_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3107901.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ873_001674"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ873_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3107902.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ873_001675"
     CDS             3205..3600
                     /locus_tag="VQ873_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3107903.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ873_001676"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ873_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3107904.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ873_001677"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ873_001677"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3107905.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ873_001678"
     CDS             5389..5994
                     /locus_tag="VQ873_001678"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3107906.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ873_001679"
     CDS             5981..7180
                     /locus_tag="VQ873_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3107907.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ873_001680"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ873_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3107908.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ873_001681"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ873_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3107909.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ873_001682"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ873_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3107910.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ873_001683"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ873_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3107911.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ873_001684"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ873_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3107912.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ873_001685"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ873_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3107913.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ873_001686"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ873_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3107914.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ873_001687"
     CDS             14213..14926
                     /locus_tag="VQ873_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3107915.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ873_001688"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ873_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3107916.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ873_001689"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ873_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4947 a         3074 c         3686 g         4740 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatt
//
LOCUS       DAVBOH010000046        15832 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOH010000046 DAVBOH010000000
VERSION     DAVBOH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15832
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.046"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ873_001690"
     CDS             complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ873_001690"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3107917.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRL"
     gene            complement(1304..2083)
                     /locus_tag="VQ873_001691"
     CDS             complement(1304..2083)
                     /locus_tag="VQ873_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3107918.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(2080..2253)
                     /locus_tag="VQ873_001692"
     CDS             complement(2080..2253)
                     /locus_tag="VQ873_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107919.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(2771..7984)
                     /locus_tag="VQ873_001693"
     CDS             complement(2771..7984)
                     /locus_tag="VQ873_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3107920.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(8028..14387)
                     /locus_tag="VQ873_001694"
     CDS             complement(8028..14387)
                     /locus_tag="VQ873_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3107921.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVSGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAIMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTG
                     VGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIH
                     FYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLK
                     DATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPT
                     QLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGN
                     KYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLI
                     QHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELP
                     DGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDT
                     ATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVAS
                     YQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGN
                     LNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGT
                     YSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSS
                     RYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVP
                     MKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPN
                     TLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDS
                     LTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLV
                     MYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKY
                     RKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKY
                     PSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRF
                     RDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFG
                     PVGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNG
                     LGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYM
                     HNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPE
                     ELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMG
                     RRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNN
                     QYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVK
                     FDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(14596..15774)
                     /locus_tag="VQ873_001695"
     CDS             complement(14596..15774)
                     /locus_tag="VQ873_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107922.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         4478 a         3212 c         2365 g         5777 t
ORIGIN      
        1 tgcagtcgaa aacactcttt aggagtgatt cgtcgtattc tcaaacggta aaattgtcca
       61 tctattaaaa caccagctac atggtaaact tgtttatctt ctccttcata gctagccact
      121 actactccca tttgaccact agttgttaat gtattcgcta taccttttcc aactctacca
      181 cgacgatact gagaacttgg tctttctaaa ttgattgaat ctccaatctc tgcttgagca
      241 tacccttttt tagttgcttc ccggactttt agaaattgga ttggttctgg aatcagtatt
      301 ttgggaattt tatctcctcc ttgcatcgta gtcagtgttg gagataagcc ctcgcttcca
      361 tagactcgac ctgtctcctt aaagctagtc ggtaaatctc caacaacgac aataccatga
      421 cgatcctgag tatttaaagt aaacatcggc tcttggtttt ccttaaagcg tctcccattt
      481 tgtctcttgt ctaatctgtc tggtgtcata caaggaatcg caaccttgaa tccttctcct
      541 tttccacgaa ctaaggttgg tgcaagacct tctgaataat agactttacc gctcattcca
      601 ctttttgatg gattcaaatt ccctagtgtt tttaaagtct cagagttagt tgtttgacct
      661 tctcgtctga aaggaaataa gagtctggta cctctctttc tagaatgtcc gataataaac
      721 accctctctc tgttttgggg aacgccaaaa tccttactgt taagcaactg ccactcaaca
      781 tcaaacccca actcatcaag tgtggtaagg attgtggtga acgtccgtcc cttatcgtga
      841 ttgagtaggc ctttaacatt ttcaagaaaa agaaaacgtg gttggatttg tttggccgcc
      901 cgagcaattt caaagaacaa agttcctcta gtatcttcaa atcccaatcg tcttcctgcg
      961 attgaaaatg cttgacaagg gaatccccca cagatgatat cgactttccc tctaagtttt
     1021 ttaaattctg catctgaaac atctcgtatg tcatgaaatt ctatttctcc ttccgtttga
     1081 aaaatggact tataagattt cctagcaaat ttatcaatct cacaaaatcc aatacactcg
     1141 tgtccaacac tttccattcc aagtcgaaat ccacctatac ctgaaaataa atcaataaat
     1201 ctcatttctt gatcacctct ttcttatcga ctaccattgt cataactgtc actccacttg
     1261 aaatgacaat aagcataact aatatccact cgattgacga catttaacca cctccttttc
     1321 taacacggtt attccaaaca gaatacaggc cattaaacac aaattcagca agtacttccg
     1381 ctcgtctaac aaagcgaaca ttgtcaagag catactgata gattctttca aaatcagtca
     1441 tagcaatttc actggctgtt tcagaaaaac cttctcgtct aaattgatct tgtaccaatc
     1501 cccaaatata atctcgatca tattttgtga ccttttctac ttttcttttc aaaataggtt
     1561 gagtattcct atcctcctca tcctcaataa ataaagaatc agtctcacta tatttagtct
     1621 cactaacttc agtctctcta ggggctgaat gtgagactgg ggccgtttca ttttcaacct
     1681 gccctagtct ttttttaaca ctaggcctgt ttgaattacc tactggggta gaagataatt
     1741 cccctaaata aatcttatta gctagtcttc ctttctcact tgaagactgt tgaacttcat
     1801 caattaagtc atattcttta agaatttttt tgatagacag taattttgac ttcgagcaac
     1861 ctaacagctt catcagttta gaattagaaa atactaaata aaccgctcct tcttcatcta
     1921 tccaaccacg actgagagat aattctaaac gatcttttaa aatagaataa gccaccttta
     1981 cttctagttt catatccata tatttctcat cctcaaaaag aattttaggt aatttgtaat
     2041 accgttctga agtttggtat tgatttgcgg taattcgttt catagcgcac ctccaagttc
     2101 tttgagtgtt aaatctccgc ttgattccaa ttgaaccaag ccactttttt ccaattcagc
     2161 cataagagag atggcttcaa caatgtcaat tcccatttca cgtactaaaa atgaaatgac
     2221 aatatagcgt gatgattgta attcttttgt cattttccct cctgaaaata aaaaaaacgg
     2281 aaagattgtg aaattccttt ccgtaacata ataaatattt gaacaccaaa ctcaacacca
     2341 aaaaaatgtt tttattgata attattgctc aatcaagcac ttataacaat gtaaaaaata
     2401 aaaatctgta ctcacaaaaa cccttgaaat tcaagggttt taagcattta ttctacttca
     2461 caatgtttta ttattttaaa tcttctagac caaccattga atagtagcca ttgagttttt
     2521 tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg aacatagaga
     2581 gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat ctactttata
     2641 ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct tttaccctat
     2701 atagaaaaaa gccatcaaat gatgactttt cagagggagc aaaaaactgt tccttctata
     2761 ttctaaacat ttaaatgtct tctttaaaca gtttattaaa gaaaccgtct gtgtttttaa
     2821 gaagggcttt gaagacctta gatttaagag caacagtgtg agagaagtca tctggtttct
     2881 tcaaatcttc ttcaactgct ttatcaaata aaggccttaa ctcatcatag ttactgatat
     2941 ggacgccatc aatatcgata gcctcaaaac ctttcttagc tttagcaaga acttccccgt
     3001 accaatgtct cttccactct tcaagagtat taaagtttcc tttcgatact ttattaatta
     3061 ttagcttatc gcttagtaaa ccgtggttgt ttttatctgc ttctgctttg tatttatttg
     3121 atacataact aataaagcca ttttcataac cataatagcc ccacatacgg aaagcattgt
     3181 gcttaaatga taatgaacca ggagcacctt gactcgtatt cccaccgtaa attcctgcca
     3241 tcatattgac atttacgtaa gctgagtttg gtgtaaaatc ttctggtcta taacgtccat
     3301 tacctggatt tccatgtttt gtcatgaagt tattatccac taaatcattg acgctagata
     3361 aagtcattac cttttcttca tctttcaaat cacggatact atcccattgg tttggaccta
     3421 aaagatcatt atactgaatc ttagagcgca tttctttgtc aatcttcttg aaccacttac
     3481 tattgtctcc tttaatttta ggaagtacag catcagcttc tacatgatca agcaacatca
     3541 tagcttcatt gtagtttctc atgtagcggt caatgtcatc acgtgtcttt aatttgtcag
     3601 gatctgggtt gtaccattgg ttaccatcat ttggacgatg gtaagccatg ttaattccaa
     3661 gtgcgccgta ttcaccatta gtcgttgagc tgtcaggtgt ttgcaacata ccttgagcat
     3721 aggcttcaac gtctgtacct tgacgatgct tatgaccacc gaagtaaagc attctatcgt
     3781 ttacgtgtgt tgtttcgtga gtaaaggctg aaataccaaa tgggctaatc atatccgtca
     3841 ccataaacaa gaccttgtca tcattatttg gattagggaa tattgatgcc atagcgccca
     3901 tacgccagtc tctatcatgg tgtcgccatg ttggaccata taattcacga attggagcta
     3961 tagggttacc tttactgtca aatcctcgac gacctacagg agaaccattg taggtctggt
     4021 tatcccaaac tggtgtcggt accatatttt gactcttaag aagtctatca cgaacattag
     4081 gcagagctaa tctggaccag aaatctaaat aagtttgttg agcatgtgca acttcatcaa
     4141 tcttagtttt gaactcatta cgagcttctt ctgtatgttt tccatatttc tcaaatgaac
     4201 tgtacgccat cgtgttatat gttgaaatta agaacatatg ggcatcttta agcgttagaa
     4261 gtggtaaaat catacgacca tgaacaccgt tatctaaacc atcgaacaca cgatgacgtt
     4321 tatctttcaa ctctgtattt gttgtcttag gttctgaaac ataaacattc ttagctgagt
     4381 ggataaacca atcattgatg tctttatcct ctgtaaacag acgcatgttg tattctaaga
     4441 agttacgcaa attactttta ccagtattac ctgcgatgat ttcacggtaa gcatcctgag
     4501 tccgatcccc tttcaagttc ttttcacttg aaccgatgtt gatgagtctg tcaataacac
     4561 ttggtgtttt accataaaaa tcaggtttga acatcatgat gttttttata cttatgtcac
     4621 cgtatttgat atcatagtaa cgattgagat aagtcagagc catcatgatt ttagctttat
     4681 tggtttccac tttcttgaga agtgatttta tcgcagcttc atcaccattc aattgatggt
     4741 cttcattttc gaccaaggat ttgactaact tatctagatt ttgcttcact tcggcaaagc
     4801 tttcttctaa gtatagatct ttaatataac cattcttacg ttcatccgta ttctctgcag
     4861 gtttatcacg tctactcatt aaatctctta cttcttgtga aatcaattcc acacttgata
     4921 attgagattt aacatcagca atcaatttat cacgattttt aacaaccata ttcggtgtat
     4981 aaacaacatc accaagacca gatacactat attcacgcac ttgttggact ttagaatcag
     5041 tattcttagt aacatccatt tcttccttag taccatcagc atagtgaacc ataatcttat
     5101 caatatctga taaatcggtc acgaattgac catccttcat ccccgtaaca gaaaggactt
     5161 ctttcttagc taagtttgaa tcttctgcaa gtttgttacc ttggttgaca atccattctt
     5221 tattataaaa tggttgaagt ttctcaatat tacgataagc taaatcacgt tcggatttgt
     5281 agtcttgagt tgacttatat tcatcttctc ttctggttaa acgatttaag cgattgacca
     5341 caggttcgtt gatttcgtat ttatcagcag taagtccaaa atttgcaatt ctcttattag
     5401 cttcatcttg actaatttct ttaattttgt cacgagaacg tttgtatgaa tgcttacctg
     5461 aactgacacc tttgacaaca aagttacgct ctaaccagcc atttgtgaaa taaccaccat
     5521 cgtagtccaa atcggaagaa ccaaagaact cttcaccatt ttcaactctc atcattgaaa
     5581 tattatcttc aagtttacca aaaggaagat tgctattgat aaatccacct gtttcaaaca
     5641 aaactttagt cttaatggtt cctttggtga ctgatttacg aattgaaccg tatttaccaa
     5701 ttcccataga gtcgttacca ttatctgttt tagcaactaa accacctata cgggctctgt
     5761 tagcaacaat atcagcctcg acatatgctt ttgcaagatt acctctccaa atctcaccgg
     5821 caatgccagc catatattga cctttatcac caacacctgt aagattaccg atgaaggcta
     5881 catttgtcaa ctgaccacca ctatcgattt tattgacgat acccgcaata ttgttattag
     5941 caactacatt accagttacc ttaacatctt caacagttgc atttttcacc atattggcaa
     6001 caggtgctat tccgtcagcc caaggcatat tgatatccac attacctaaa ttaatatttt
     6061 tcacagaacc attttcaaca cggtcaaata agggacgggc aatgttatga attgtatatt
     6121 gtttaccatc aacacttgat agatgtccct taaacgtacc tggaacatat tgtttgttag
     6181 gtgttggtac attcgttgca ttcaaatctg ctccgatttt aaatgtacca tttttatcag
     6241 cattcatggc atctactaac tctttaaagt tataataaac gtcatcaact tttggaactg
     6301 gtttttcaat ataatgaaca tacttgttac gaaccttcgt tgggtctgta tgttgaatca
     6361 aatcttgagc ttcggcagtg attttataaa gtttcttacc ttcttcagtc acttcttcaa
     6421 ttttatcaac tgctaaacgt gttactttat tatcacgact agtaattttt aagtacattt
     6481 tcttcacatc ttcatctgaa ggtttttcag tcataaaatc actaggtgtt tcagtaccat
     6541 cgtcatttac cttcactaaa ttagtagatg cgatattttt aatttcaact tttttcaaat
     6601 ccaagcgaag tggtttctct tctaatgttg cagtttcttc tcccttgcca cggtcatagg
     6661 tcatagtggt ctctatctta tagtccttgt agaattttaa atcttctacc tgcttatcta
     6721 attgctctga agtcaaatct actgttttga caatttcatt tccatcttta attgtcgcag
     6781 taattttatt gattgtgact ccatctgtat taactaaatg ataagaaaga gttgcggatc
     6841 ggtttaatac atttgtattt gttctatcta aggtcaaaac aggagccgtt ttttctttag
     6901 gtttttcttt ggtacctttt acaagaattt taggcttcat ttctttcaaa atagttactg
     6961 tttcaactgg gtcactgatt tttttgccat gtaactcttc atagctagta acaatttgac
     7021 gttcgccatc ctcaccaact tgtctaacag aatcatcgcc tataaatttg ctaggatcag
     7081 attcttctat agtggtttta ggaatagtct ctgtccgaat atcggtatgt aaagaaggca
     7141 actcttctct ttctgatgca acttctgaaa ctgtagatat tggttcagta tactctggaa
     7201 tgtcgctaac aggtggctca atcaagtttc cattttcatc cactcctgtt gtacctactg
     7261 gctcagtata ttctgggatg tcgttaacag gtggttcaat caagtttcca ttttcatcta
     7321 ctcctgttgt ccctactggt tcagtgtatg ctagtttctc atgaacttca ggctcaacaa
     7381 ggtttgcacc tattggttgc gtatagtcag gcttctcatg aacttccggt tcgcctttct
     7441 ctgttacaac tttgggttgc tcaactggcg aaacagttga tgctggagaa accgacgaaa
     7501 cagttttatc atcaagctcc aagtaaccaa catatctgta accagaaatt tgcaacacac
     7561 catcacgtcc agactcatgg atgttagcat tcaaattaag tgctgaagca gttgatagtg
     7621 taactaaacc tgtcgcccct acaatcaaaa atgtagctat ttttttattt ctattatctt
     7681 ttgtgataat cacaataaga ctcccgatag ctaacaaacc caatgcagtc ataatagatt
     7741 gagaacttcc tgtgtttggt agtgcgtctt tttcataatc caaagcatat gactctttgg
     7801 attcatcagg tctaccttgt ttgagttgat cacgttcagt ttgtgtcaaa ctactataat
     7861 ctaagtaatg ataagtcgat gcaccaacaa ctgacggtgc aaataaaaga ctccccaaga
     7921 ataccgaacc aacaataccc tttattttcc gaatggaaaa tttatctttt tttaataatg
     7981 acaattctaa tcctccacct tcacttttta tttcctaata gtaaacacta ttttttattc
     8041 tcaaaaattg aacttctaaa atcaccggtt tggtcaagat aagctttaaa gattgctttt
     8101 ttcagtttaa gaactctact atttgtctca ggatataatt tggcaacttc atcctcagca
     8161 tcaaatttta ctgcatcttc aatcattttt tcaagtctat taatattatc aatagtcact
     8221 ttctgttgtc gagcccaaga accgtttgga tcgataaaac taactttatt taactttcca
     8281 aatttatctt ctctttcttt atacatatct ttcttgaaat ctatccaaga attatactgg
     8341 ttattaaata cttttgaaag aacaatttca tcagtaacta aacctatttg tttaccatat
     8401 gatgtaataa cttttccttg agctttcgct tctttttcat actgattaga aatatatgga
     8461 accataccgt ctttgtaccc cttggctgcc aataactcaa atgcaatacg tcgtcccatt
     8521 aaatctcctg gtgttcctat tttactgctc aatgctgaat aaattggtga gaatagatta
     8581 attgtatagt agccattccg cttataagtt gcttcatcta cataacctct tcttgttata
     8641 atatcatgtt ctatcaaact gttaaatgta gttaatttag taagttcttc tggttttaat
     8701 ctacgtacaa cattcgttgc ataaacagaa tttccatcag gatcaggttt atattcattt
     8761 tctatttttc ttaataaatc atatttttga tttgtatcta atttagctac agctttacct
     8821 tctagtattt caagcatgta tattacatca aacatattat gcatatactt atttagatca
     8881 tcaacacttc caaatcgttg agttggatct gctacttgaa gccttgttga ttcttctgat
     8941 tgatcatatt ttaatatgga attaatagtg actgttggat cattaggatg atcaggagct
     9001 tgtagcagtc ctttagcata aaactctggt ccaagtccat ttcgtcttcc atagcctcca
     9061 agataaattt ctctatctga gttatgtgtc atttcgtgtg tataagttac cgcaccatct
     9121 ttatcaagca tgcgatatgc catataatag aatgcatccc ctgtagcata tgctccatta
     9181 gaattatgaa caacattatt tcccactgga ccgaagaaat gttttatagc tggatgatta
     9241 gtttcaaaag ttgcttgata tgtatcttta tcttcttttt catctgtacc aaatctaaat
     9301 gcatcataga ctagaacact tctatataat ttttctttat ttttatcatc tagtattcta
     9361 taccaataat catagtgatc tctaaatcta acagccgctt ctttagcttt tttctcaaca
     9421 tagtcattta aatcagttcc tgctggatgt tctttacttc tatatctatc ataagcaccg
     9481 aaacctatag tcgaaatgtt ggctataata aacaccgatt tttcaggtaa tgttaatagc
     9541 ggcaacacca tacttggata tttccaagat gggctagtta atctatcata tactccaatt
     9601 gaatatggac taccagctat tgattgctta tcacttacct ctttaatagt agatttttct
     9661 tctacaatat atgctttagt ttgttcttta aaccactcat tatttgtttt atctggtaca
     9721 aatgcttttc tatatttctc taatgcatca aataaattat tagtcttata atttttcgct
     9781 aataaaacat tataagttat aacattattt tttgctagta agttattata tcccgattta
     9841 cctagttcga taacattatc taacgctgaa ctatttgatt taccgaagaa atccaagtgg
     9901 tacatgacta aatctttcgc ttttgtatca cgatatttga agtcgtacca acgctctaag
     9961 tatgttaatc ctagaagtaa agcttcttta ttatttttaa ttttctcgat tacataatta
    10021 tctattacct tattgttatt ttcagctatt gcagcatctg cagtaagaag ttttgtcaaa
    10081 ctatctttca aattagtttt tgtggtattg aattgttctt ctaaatataa ctccgttaaa
    10141 ctaacatcct tagaaacatc taatactttt ctaattgcct ctgatttata ttctacacta
    10201 tttaatgctg gtaatacttc atctaaaata ttttgataat tgcgaagtaa tgtattcggt
    10261 gtataaatta agtttgtacc gcctattcta tactctgcta catttgaaaa atcagtttga
    10321 taatttacat taagtgtctc tgatgtatta tccgcgtaat atagtaatag tttatttata
    10381 cttgatttat ttttgttaat atcactaatt acttctttat ctttcatagg gactactgac
    10441 aataattctt tattataaag attactactt gtctctacta aatttccgta cttaacaatt
    10501 gtttctctat tataaaacgg taatagtttt tcaatatttt tatatacttt ttcttttgat
    10561 gaatcagcat tctcaagatt tttatagtca gttacatatc tagaagagaa attaaaatct
    10621 tctgttttaa tagtattttt agatacaaaa gtagcttttt tctcttttat ttgtgcatct
    10681 tctaatactt ctcctctttg aacagtagaa tccttagtta agatttcatc atcttcttgt
    10741 actacgttca caaccttatt atttttatta ctgtatgtgc catttgcttt tataccatta
    10801 aaattataac ctgcaatagc attaccattc gttacattaa catcgcttag tacattagaa
    10861 agtcgaccgg atttttctaa tcctccaacc ggatcccaaa gattaccaac tactccacca
    10921 acgtttgcaa aacgttgaac attatttaga tttccttcag cataactatt actaataagc
    10981 gcactatttt ctactgcacc aactattcca ccaatagact ggtctccttg tgttgcattt
    11041 gaagataaat cgattgatgc gaacgactta tctattaatc ccctcggacc agaaagtttg
    11101 cctactaaac ctccgatttg ataactagca actgttttat atgtattagt tattctacct
    11161 gtatagctac tgttagaaat agtagaatta ttaacttgtg atactaatcc tcctatgcta
    11221 cgttccccag ctatcgctcc atcagcatga acgttatcaa tatgagtatt gttatttgct
    11281 tctttcgcaa gtgttgcagt atcgtccttt gcggaaatat taacatcttt tagtgaaagt
    11341 ttttctactg tagcaccatt taattcccca aataatggtt ttttcaaatt ataaatagca
    11401 taatatttct cattatttgt tcctactaat attccatgga atacattatt cacataactt
    11461 tcttgaccat ctggaagttc aacttcacga gcatccatag ttgctcctaa acggaatgtg
    11521 ccattaggat tgctattcat tgcatctact aaatttttaa atgatgtata taccccagtt
    11581 tcactttgct gagtttttgg taaatagtat gtataatttt ctagtacatt attattttca
    11641 tgttgtatca gactatttgc acttgctact atcttataaa catctctatt atctttagta
    11701 tcattagtaa tgcttgtaac tggtagcatc acatctttaa agttctctga tttaactttc
    11761 ataaagtaat tttctgcatt acttggtaaa gaagcaagtg aagttacatg tcgatactta
    11821 ttaccatctt ttgaatatag ttctacagaa gatatatttc taagttctaa tttcttaata
    11881 acttcttttt catctttagc gtcatctttt ttctcatctt tatgacgata aagttcatcg
    11941 tatactggtg gaatttcatt acctgctata atactcttaa tccaagctaa ttgtgtagga
    12001 gataaaatta atccgcctga gcgattttgt gctccatttt gatgcacacc aataacttca
    12061 ccattagcat taaatattcc tccaccactc ataccaggat ttccaccttg atattgaaca
    12121 ccgtaggtgt tattcgcata ttcttgttcc atttctaccg tagcatcttt taagtgcgta
    12181 tatttcccag ctggatatcc atgaacattt agtttgtcat taagatttac tttcgaataa
    12241 tttttaacta attctacatg ttctctgcca gttgtttcag gtagcttaat cactgctaaa
    12301 tcatagataa atccttttgg ataatctttt ttattataaa aatgaatatt gttagcagta
    12361 aatgttcctt tttgtccatc aggagtcacc cactcatata cgtttttaga tttatcacct
    12421 ctaaattcgc cagtagtatt atcagtagaa ttattaatga aattatgtgc tactgttaaa
    12481 agtacatttg gtgcaataaa agtagctgat cctactccag taaccttcga cgaatctgta
    12541 ataaagttca tattaattaa tgcactagat tttttctgaa tactcatttc ttctggtgta
    12601 ttagtatttt cattatttgg tttagtatct tctgcactag gttgttcgat tttaccagta
    12661 tattctttca gtgcttctac tttttctggt tctactattg ctccggcttg cactcctgtg
    12721 tattccttcg gtgcttctac cttctctggt tcgactatcg ctccagcctg cactcctgtg
    12781 tattccttcg gtgcttctac tttctctggc tcgactatcg ctccggcttg cacccctgtg
    12841 tattctggta gtggtgctac ctgctctggt tcaacaatag cgccagcttg tactccagca
    12901 tattccggtt caactttttc aggttcaaca atagctccag cttgtactcc tgtatattct
    12961 ggtagcggtt ctacctgctc tggatcaccc ttgtcagtca tgattgcctc tggtaacgct
    13021 ggttgaactt ctggtacgcc tttatcactt actacagctt ctggcaactc tggttggact
    13081 gctgactcac ctttgtcggt taatacagct gctggtagtt caggctgaat tgcgggttca
    13141 acaatagctc cagactgtac ttccttatgt tctgcaccag tctcagcttg ttcctttata
    13201 acttgagctt ttttagtacc tttttcgact attcttgaaa caggcgcagt cgttgaagtt
    13261 gaaataattt ctcgtgaaac ttcttcattg tttacagaaa atattctgac gatttcaact
    13321 ttcttaccta atgcaccttc ttgttttact cttacagttc cttctgctaa atcaggattt
    13381 tcttgaattt cttcttgaaa atctattttt gtttctatag tttcgtcacg atataagagt
    13441 tccggtttgt tcaactgacc tgatagcact tcatcctgtg gatttaatgt atttacccca
    13501 gtcttttcct ttggagaaat cttctcctct ttcttcgttt ctagattctt atgttcggct
    13561 aattgttctt gagaatctga agattgtttc tcttcttttc ttggattgat taattcagta
    13621 gagaaaggtt tttcaactac ttgaacttct gtcggcttag ttgaagaaac aggtgtttgt
    13681 tcctgaatag cttgtactgt tgatggatgg tctacaaaat ttggtgtaac attataatcc
    13741 accttttgtt gttttgtagg agtggctgct gatttttctt gattacttac ttcaaaatca
    13801 gaagtcgttt ttccctcttt gatatatcca atataagtgt aacctgaaat ctctttagga
    13861 agaggtaatt tttctccaga ggtcaattca tagtccgtat tgtaatttag caaaagatga
    13921 ttttctaaag catggactga aactaagaca ccatttccca ttcccgcaac caatactaaa
    13981 tgtaataccg ttttattctt aacctttttc ttggaaacag caaaaattaa aattcccaga
    14041 gcagctaagc tagcaccaga aactagggct tgcctctcat tcttgcttcc agtatttggt
    14101 aattccgcca gttgattttg agaatttaac ttataaacaa gataataagt ttcatcatca
    14161 ttctccacgt atgtcggaat atcatagaca agctgcttct tttcttctga tgatagctct
    14221 gaatctgcca catatttata gtgaactccc gcagtttctt gagcatccac agatgaacta
    14281 gctaatacag acataaaaaa taaacttgaa atcgttgcag atacaagtcc tactgataat
    14341 tttctaaatg aaaaacgctc ttgtttttca ccaaaatact tttccattat tcctccttga
    14401 aataaaattt atatatgtta caaagacctt tattatatta gtgtattatc tattatctat
    14461 agaaaaggca gtatacctta attatactct taatttacaa aaaagtctta aaattgagat
    14521 gcgctttcat actttgtttt atattatttg ggggtacaat aacacctacc atgaaattta
    14581 cacggtaggt gttactcata tcactaatcg ttctaaaaat ggtttgaggc agttgaggag
    14641 aattccttct atccagcttc cttgtgctga tgagcgatgg tcttcctgca ggcttttttt
    14701 tagaaaatct cggacttgtt ctggtgcgat ttcaaattca aaggctttca ttttatagaa
    14761 aaagtcgatg agatgatcgg acaggtattc agttgaaaag ggtacttcac cactttttcg
    14821 atattctaat aagagcctag aaaatcgagc tttttcttca ggaagctcac gaaaatagga
    14881 attgaggagc caagtctgct tctgttttct ttcaattgga tcctgactgg caattcgttg
    14941 gtctttttcc agctcttttt ggtattgttt ggccttgata gcccgttctg ctctattttt
    15001 accaaaaaga attttttccc acttgcgttc ttcttgagtc agggtctctg taaagccaaa
    15061 gtaatcttga taagcacgct ctgcgggtcc catggctaga accagattgt ctgcatattg
    15121 cttggcgatt ttatccctct tcttgcgttc tttctctgcc tggatacgga gttcttgttc
    15181 gtagtcaatt ttctccttgc ctagcttgac aaggtagagt tggtcatccg atttcccaag
    15241 taaaaagggt ttgatacact tttcaaggac ttcttccatc cgagcctttt tctttggttc
    15301 cgccttggtc caacttcctc cctgaaagac ttctaggaaa agctggtagt ctctctcagg
    15361 cgcaaattga ttgccacgat tgggtttgaa aacacctttt tcccagagcc attttagaag
    15421 tcgctcgtca aagtcacttt tattgacctt gattttttct tttttctgag cttttctggt
    15481 tagattttca acctttctga gcagtttttc ttcctcttcc aattgctggt caagggacaa
    15541 tcgatgaaaa tgacgaacac agtcgctacc aattggaaag aggcgttggc ctgtgacacc
    15601 gttaaagagt tcataagcgt atttgatggc atttccacag acacaattgc tacggccgat
    15661 accgttaaaa atcaaggaaa cttcattcca ttccttggta gcttgttccc aagtatccgc
    15721 tttcgaagcc tgtaaaactg catcgtgcag ggattttcta actggaagtg tcatgaggtc
    15781 tcctttctaa tactcaataa aaatcaaaga gcaaactaga aagctagccg ca
//
LOCUS       DAVBOH010000047        14749 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOH010000047 DAVBOH010000000
VERSION     DAVBOH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.047"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ873_001696"
     CDS             83..880
                     /locus_tag="VQ873_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3107923.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ873_001697"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ873_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ873_001698"
     CDS             2383..3657
                     /locus_tag="VQ873_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3107924.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ873_001699"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ873_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3107925.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ873_001700"
     CDS             4786..5088
                     /locus_tag="VQ873_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3107926.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ873_001701"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ873_001701"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3107927.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ873_001702"
     CDS             5962..7302
                     /locus_tag="VQ873_001702"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3107928.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ873_001703"
     CDS             7280..7492
                     /locus_tag="VQ873_001703"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3107929.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ873_001704"
     CDS             7489..8364
                     /locus_tag="VQ873_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3107930.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ873_001705"
     CDS             8357..9172
                     /locus_tag="VQ873_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3107931.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ873_001706"
     CDS             9165..9596
                     /locus_tag="VQ873_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3107932.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ873_001707"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ873_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3107933.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ873_001708"
     CDS             11272..12000
                     /locus_tag="VQ873_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3107934.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNCGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ873_001709"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ873_001709"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3107935.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ873_001710"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ873_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14360..>14749
                     /locus_tag="VQ873_001711"
     CDS             14360..>14749
                     /locus_tag="VQ873_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3107936.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDF"
BASE COUNT         4390 a         2670 c         3481 g         4208 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgaa attgtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aacaactctt tgatcaggta gcaagcttgt tggaagaacg
    14461 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcacacaga
    14581 tattgttcat aatctagctg aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt
    14641 tcacaatatg attgcgccag gtaaggaagt agaagtatcc ctactcttct ttatcattaa
    14701 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggacttt
//
LOCUS       DAVBOH010000048        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOH010000048 DAVBOH010000000
VERSION     DAVBOH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.048"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ873_001712"
     CDS             complement(83..646)
                     /locus_tag="VQ873_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3107937.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ873_001713"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ873_001713"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3107938.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ873_001714"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ873_001714"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3107939.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ873_001715"
     CDS             2112..3782
                     /locus_tag="VQ873_001715"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3107940.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ873_001716"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ873_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3107941.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ873_001717"
     CDS             5341..6045
                     /locus_tag="VQ873_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107942.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ873_001718"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ873_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3107943.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ873_001719"
     CDS             7389..8198
                     /locus_tag="VQ873_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3107944.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ873_001720"
     CDS             8289..8531
                     /locus_tag="VQ873_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3107945.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ873_001721"
     CDS             8533..8787
                     /locus_tag="VQ873_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3107946.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ873_001722"
     CDS             8834..9577
                     /locus_tag="VQ873_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3107947.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ873_001723"
     CDS             complement(9867..10853)
                     /locus_tag="VQ873_001723"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3107948.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ873_001724"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ873_001724"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3107949.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ873_001725"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ873_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3107950.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4393 a         2477 c         3188 g         4286 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 caatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBOH010000049        14208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOH010000049 DAVBOH010000000
VERSION     DAVBOH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.049"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ873_001726"
     CDS             <1..211
                     /locus_tag="VQ873_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3107951.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(526..2217)
                     /locus_tag="VQ873_001727"
     CDS             complement(526..2217)
                     /locus_tag="VQ873_001727"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3107952.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2353..2799
                     /gene="argR"
                     /locus_tag="VQ873_001728"
     CDS             2353..2799
                     /gene="argR"
                     /locus_tag="VQ873_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3107953.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2850..5384
                     /gene="mutS"
                     /locus_tag="VQ873_001729"
     CDS             2850..5384
                     /gene="mutS"
                     /locus_tag="VQ873_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3107954.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5531..7225
                     /gene="patA"
                     /locus_tag="VQ873_001730"
     CDS             5531..7225
                     /gene="patA"
                     /locus_tag="VQ873_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3107955.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7555..7818)
                     /locus_tag="VQ873_001731"
                     /pseudo
     CDS             complement(7555..7818)
                     /locus_tag="VQ873_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8016..9782
                     /gene="patB"
                     /locus_tag="VQ873_001732"
     CDS             8016..9782
                     /gene="patB"
                     /locus_tag="VQ873_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3107956.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMCNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9921..10610
                     /locus_tag="VQ873_001733"
     CDS             9921..10610
                     /locus_tag="VQ873_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3107957.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10614..10793
                     /locus_tag="VQ873_001734"
     CDS             10614..10793
                     /locus_tag="VQ873_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107958.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10780..12129
                     /locus_tag="VQ873_001735"
     CDS             10780..12129
                     /locus_tag="VQ873_001735"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3107959.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12253..13713
                     /locus_tag="VQ873_001736"
     CDS             12253..13713
                     /locus_tag="VQ873_001736"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3107960.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13727..14161
                     /locus_tag="VQ873_001737"
     CDS             13727..14161
                     /locus_tag="VQ873_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3107961.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4160 a         2749 c         3194 g         4105 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccact aacagttgaa gatcaagcct ataaccatgc
       61 gctatccaag gagagaagca aggtcgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg
      241 tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga
      301 ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg
      361 tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa
      421 tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg
      481 gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg
      541 cgcttctact ccaagcaagc gaagggcttc ttttagaacg actgcggttg cgtagctgag
      601 ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt
      661 gttaaaggat tgagctaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc
      721 tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc
      781 agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat
      841 agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac
      901 catagcttct aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt
      961 aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt
     1021 agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct ctagcaagat
     1081 gacattccct ttacgagtag agagcttctt cccttccttt gtaaccaaac caaaaggaac
     1141 gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc aagacagctt tgagctgttt
     1201 aaagtgggca gattgttctt gaccaacgac atagatagat ttagcaaatt ggtattcgtt
     1261 tttacggtaa agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt
     1321 cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt gggcaccttc
     1381 tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt
     1441 gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt
     1501 aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc
     1561 attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc
     1621 ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc
     1681 ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc
     1741 tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct
     1801 atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact
     1861 agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat agtgttcttt
     1921 ttcagttgta acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt
     1981 aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag
     2041 ttcagccgca atcatttgtg gtgctttacg ttcgactttg gcaagagaaa aagcagggaa
     2101 agcgatgtca cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg
     2161 gtccaggcta tcaatgatgc tagccaattc gctagcaatc aattcttttg tattcattaa
     2221 gagctccttt ttggactttt ctactatttt aacacaattt taaagaaaga agaaaaaatt
     2281 tttgaaatct cttgtttttt tggtataata tggttataaa tatagttata aatatgcacg
     2341 caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag
     2401 gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg
     2461 acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat
     2521 gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg
     2581 tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg
     2641 ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggataaatg gattttagga
     2701 acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc
     2761 atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa
     2821 gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc
     2881 aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg
     2941 atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct
     3001 taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt
     3061 ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc
     3121 agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta
     3181 cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca
     3241 tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt
     3301 atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc
     3361 gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga
     3421 tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc
     3481 gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc
     3541 agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc
     3601 agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga
     3661 aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct
     3721 tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag
     3781 tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg
     3841 gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg
     3901 atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag
     3961 ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg
     4021 agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa
     4081 ttatccggac tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga
     4141 ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca
     4201 agattgacta caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa
     4261 atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg
     4321 aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg
     4381 aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag
     4441 ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa
     4501 cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc
     4561 gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga
     4621 tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct
     4681 atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg
     4741 aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact
     4801 tggtttcggg tcagtcaacc ttcatggtgg agatgatgga ggccaataat gccatttcgc
     4861 atgcgaccaa gaactctctc attctctttg atgaattggg gcgtggaact gcaacttatg
     4921 acgggatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga
     4981 ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta caacacttgg
     5041 tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg
     5101 aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag
     5161 cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga
     5221 gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg
     5281 cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta
     5341 tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag
     5401 ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac
     5461 atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta
     5521 aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct
     5581 cctgatgaca ggtttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt
     5641 cttaggcgcc ctccttactg ggaaatatga agctatttat agtatcgggg cttggttgat
     5701 tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat
     5761 tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc
     5821 ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat
     5881 caaccagatt cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt
     5941 gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt
     6001 tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg
     6061 ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg
     6121 tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga
     6181 ggtctcagac gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga
     6241 accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg
     6301 aatggttcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag
     6361 ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat
     6421 gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga
     6481 tatcccagat gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc
     6541 aatggacaat gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt
     6601 tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct
     6661 ctttgatcca cagaacgggg ccattaaaat cggtggcaag gatattcgag aagtgagtga
     6721 aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac
     6781 gattgcagat aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc
     6841 agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc
     6901 agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg
     6961 tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag ccttggatgc
     7021 caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat
     7081 tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca
     7141 aggacgattg attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg
     7201 tgaaatctat gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct
     7261 aaattatttc ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc
     7321 cttgaaaaag tccatttttt caaaggtaat cctgtgttga tttcagaaat tacatcactt
     7381 tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt
     7441 tgtaaggtgg atgatggcta cattgtaatg ttttccttat tctaacttag tcttaagata
     7501 ggccttaaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtgcctaccg
     7561 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgat ctgactgata
     7621 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
     7681 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
     7741 gatgatcgag ttgaactcag ccatcaagtc attgacacat gtttccgcct tgtcaatgag
     7801 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtttatgcg ttatcaaact
     7861 catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg
     7921 aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag
     7981 ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc
     8041 attattttaa ggtttacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga
     8101 cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt
     8161 tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca
     8221 tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc
     8281 tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc
     8341 ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt
     8401 ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt caggtcatgt
     8461 gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg
     8521 ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa
     8581 tggcacgcaa atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg
     8641 atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg
     8701 caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct
     8761 caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct
     8821 ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt
     8881 tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag
     8941 cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg
     9001 atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg
     9061 ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca
     9121 gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt tcaggaaaaa
     9181 cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg
     9241 atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat
     9301 tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag
     9361 atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg
     9421 aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag
     9481 ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc
     9541 tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag catgccatgg
     9601 aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca
     9661 atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg
     9721 aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat
     9781 gagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag
     9841 ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag
     9901 cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc
     9961 ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca
    10021 ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg
    10081 attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt
    10141 tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt gacgaatttg
    10201 aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg
    10261 gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact
    10321 ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg
    10381 ctaagctatt tgggaaagaa agtcaggtca attcagtcca tcgtcaaagc attaaagatt
    10441 tggcacccaa tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg
    10501 agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg
    10561 aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac
    10621 atctggtcgt tctttctttt attttttcaa aatttttaga atgtggtatt ttacgcaaac
    10681 gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta
    10741 agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat
    10801 tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa
    10861 gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga
    10921 tggttggacc ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct
    10981 gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt
    11041 ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa
    11101 gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct
    11161 gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt
    11221 acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac
    11281 ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt
    11341 aaggttgaag cagacgctaa cggttgggaa acatttgttg ttccagatga tatcggtgga
    11401 cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc
    11461 aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct
    11521 gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca
    11581 actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa
    11641 ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc
    11701 tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa
    11761 acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac
    11821 cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact
    11881 gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca
    11941 gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc aattgccctt
    12001 tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt
    12061 aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca
    12121 cgtctataat agaagaaaag agtggtttac ccactctttt tactctcttt atccatagaa
    12181 attggactca gtcaagactt gtgatataat atagaaagca aaaaggcaga tgcctagata
    12241 ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta
    12301 ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg ccatcatggt
    12361 ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa
    12421 cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca
    12481 catgagaatt atcgccagtc tgagcgttta gacttgtatc aaaaatacat tgaccaacta
    12541 ttagctgaag gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgc
    12601 gaacgccaag aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt
    12661 gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat cccaactgtt
    12721 cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggcgatatc
    12781 gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga cggttaccca
    12841 acttacaact ttgccgttgc catcgatgac cacgatatgc aaatctctca tgttatccgt
    12901 ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaatc tcttggttgg
    12961 gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg taagaagtta
    13021 tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt
    13081 ccagaagcag tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag
    13141 attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca
    13201 gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa gaatgcagac
    13261 cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac
    13321 aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc
    13381 ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc
    13441 atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg
    13501 acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt tcaaaaagaa
    13561 acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg
    13621 catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat
    13681 atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga
    13741 aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag actttgttta
    13801 tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta caggattctg
    13861 tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc tcttcaatat
    13921 gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc
    13981 ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa
    14041 tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt
    14101 cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta atgagcgata
    14161 gaagagtcag tataattttg gctcttttta ctataagttg aaaaaata
//
LOCUS       DAVBOH010000050        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOH010000050 DAVBOH010000000
VERSION     DAVBOH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.050"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ873_001738"
     CDS             276..890
                     /locus_tag="VQ873_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3107962.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ873_001739"
     CDS             994..1824
                     /locus_tag="VQ873_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3107963.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ873_001740"
     CDS             1978..2832
                     /locus_tag="VQ873_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3107964.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ873_001741"
     CDS             2932..4305
                     /locus_tag="VQ873_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3107965.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ873_001742"
     CDS             4298..5359
                     /locus_tag="VQ873_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3107966.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ873_001743"
     CDS             5361..6053
                     /locus_tag="VQ873_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107967.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ873_001744"
     CDS             complement(6083..6652)
                     /locus_tag="VQ873_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3107968.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ873_001745"
     CDS             6787..7401
                     /locus_tag="VQ873_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3107969.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ873_001746"
     CDS             7403..9049
                     /locus_tag="VQ873_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3107970.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ873_001747"
     CDS             9061..10347
                     /locus_tag="VQ873_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3107971.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ873_001748"
     CDS             10399..10932
                     /locus_tag="VQ873_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3107972.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ873_001749"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ873_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3107973.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ873_001750"
     CDS             complement(11773..13035)
                     /locus_tag="VQ873_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3107974.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2452 c         3007 g         3816 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggtccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBOH010000051        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOH010000051 DAVBOH010000000
VERSION     DAVBOH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.051"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ873_001751"
     CDS             <1..367
                     /locus_tag="VQ873_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3107975.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ873_001752"
     CDS             complement(442..972)
                     /locus_tag="VQ873_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3107976.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ873_001753"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ873_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ873_001754"
     CDS             1984..2661
                     /locus_tag="VQ873_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3107977.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ873_001755"
     CDS             2648..3445
                     /locus_tag="VQ873_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3107978.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ873_001756"
     CDS             3462..4565
                     /locus_tag="VQ873_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3107979.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4572..4763
                     /locus_tag="VQ873_001757"
     CDS             4572..4763
                     /locus_tag="VQ873_001757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3107980.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSSKHCFEVVYRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ873_001758"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ873_001758"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3107981.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ873_001759"
     CDS             5887..6840
                     /locus_tag="VQ873_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3107982.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ873_001760"
     CDS             complement(6902..7108)
                     /locus_tag="VQ873_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3107983.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ873_001761"
     CDS             7160..7636
                     /locus_tag="VQ873_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3107984.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ873_001762"
     CDS             7645..8316
                     /locus_tag="VQ873_001762"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3107985.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ873_001763"
     CDS             8447..8785
                     /locus_tag="VQ873_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3107986.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ873_001764"
     CDS             8788..9417
                     /locus_tag="VQ873_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3107987.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ873_001765"
     CDS             9657..10808
                     /locus_tag="VQ873_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3107988.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ873_001766"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ873_001766"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3107989.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ873_001767"
     CDS             11865..12638
                     /locus_tag="VQ873_001767"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3107990.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ873_001768"
     CDS             12616..13077
                     /locus_tag="VQ873_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3107991.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOH010000052        13150 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOH010000052 DAVBOH010000000
VERSION     DAVBOH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.052"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(278..1501)
                     /locus_tag="VQ873_001769"
     CDS             complement(278..1501)
                     /locus_tag="VQ873_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3107992.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1669..2991
                     /locus_tag="VQ873_001770"
     CDS             1669..2991
                     /locus_tag="VQ873_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3107993.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2993..4879
                     /locus_tag="VQ873_001771"
     CDS             2993..4879
                     /locus_tag="VQ873_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3107994.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5047..5391
                     /locus_tag="VQ873_001772"
     CDS             5047..5391
                     /locus_tag="VQ873_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3107995.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5401..6813
                     /gene="lacG"
                     /locus_tag="VQ873_001773"
     CDS             5401..6813
                     /gene="lacG"
                     /locus_tag="VQ873_001773"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3107996.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6883..8562
                     /locus_tag="VQ873_001774"
     CDS             6883..8562
                     /locus_tag="VQ873_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3107997.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8688..10127)
                     /locus_tag="VQ873_001775"
     CDS             complement(8688..10127)
                     /locus_tag="VQ873_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3107998.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ873_001776"
     CDS             complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ873_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3107999.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11668..12516
                     /locus_tag="VQ873_001777"
     CDS             11668..12516
                     /locus_tag="VQ873_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3108000.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12531..13079
                     /locus_tag="VQ873_001778"
     CDS             12531..13079
                     /locus_tag="VQ873_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3108001.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         4027 a         2106 c         2807 g         4210 t
ORIGIN      
        1 gagaattgta aaaacaaaaa tggggatttc atataaagtt tattctagga gtatgtatct
       61 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttat aataataaaa
      121 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      181 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      241 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      301 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      361 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacgaagt
      421 ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      481 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      541 ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct aaattataag
      601 ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt tttagtacag
      661 ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca tccgaaatat
      721 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      781 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      841 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      901 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      961 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
     1021 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1081 ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1141 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1201 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1261 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1321 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1381 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1441 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1501 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1561 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1621 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1681 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1741 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1801 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1861 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1921 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1981 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     2041 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2101 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2161 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2221 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2281 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgg aattgttgga
     2341 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2401 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2461 gtttggttac aatttactat agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2521 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2581 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2641 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2701 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgccttg
     2761 attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt aatccttccg
     2821 tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg gcgaggagct
     2881 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2941 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     3001 cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3061 ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg aagcggatat
     3121 ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct cattagacaa
     3181 gggtaaggga agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3241 gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact ttgttccaga
     3301 gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag ccagttacta
     3361 tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag atttcattga
     3421 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cttactcttt
     3481 tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac aattttcaaa
     3541 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3601 tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt caaaatttgg
     3661 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3721 gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt caaatccaga
     3781 tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3841 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3901 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3961 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc tatgggcgcc
     4021 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4081 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4141 ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4201 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4261 tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag atgtatctta
     4321 tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg ccggattccc
     4381 tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa gaagttatga
     4441 agaattgatt gaagaatact tttctgcttt gtatgggtca aattggcagt ctgttgttga
     4501 atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa ttggcagtcg
     4561 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4621 gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4681 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4741 cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata tccgtgggca
     4801 cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4861 cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt cagagaagat
     4921 tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga ctttctattt
     4981 atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga ttgaggagga
     5041 agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt cgcttacgca
     5101 ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg atattttgaa
     5161 caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca tcgagaacag
     5221 actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt tatcatgatt
     5281 catggtcaag ataccttgat gacaacgatg ctattgtatg atcaggtcaa gttttttatt
     5341 gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg aggattagtc
     5401 atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggagc tgctaccgct
     5461 gcttatcaag tagagggtgc aactagggta gatggcaaag gaacaaatat gtgggatgtt
     5521 tatttgcaag aaaacagtcc gtttttacca gatccggcta gtgattttta ttatcgttac
     5581 gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt atctatttct
     5641 tgggttcgta tatttcctga tatagatggg gagcctaata tattagctgt tcgttattac
     5701 catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc tttacatcat
     5761 tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga gaatattgat
     5821 cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa gcattggttt
     5881 acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca gtttcctcca
     5941 aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt gttggcgcat
     6001 gctcttgcag tccgcgaatt tcatcaatta gggattgagg gaaagatagg ttgtattcat
     6061 gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc agctaaacgg
     6121 tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta ctacagtgag
     6181 gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt tattattgaa
     6241 gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt tgggatgaat
     6301 tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga atttaattca
     6361 acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt tgtaaaaaaa
     6421 cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt atttgatatg
     6481 ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac tgaaaatggt
     6541 acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga cagtaagaga
     6601 atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag aggagtcaat
     6661 attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa tggctacaat
     6721 aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat taagaaaagt
     6781 gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg atgtttaata
     6841 tattttaact atgagcttaa attttttaca ggaggagttt ttatggataa gttagtcgct
     6901 gccattgaaa agcaacaagg gaaatttgaa aaaatttcta ctaataatta tatgatggct
     6961 attaaagatg gatttattgc tactatgcct ttaattatgt tttcaagctt tttgatgatt
     7021 attattatga ttcctaaaaa tttcggagta gagttaccga gtccagctat tgcctggatg
     7081 aggaaagtgt atatgctaac catgggagtt ttgggtatta ttgtttcagg gacagttgca
     7141 aagtcattgg ctggaaatgt taatagaaaa atgcctcctg gaaaggtaat aaatgatact
     7201 tctgcaatgt tggcggccat atgtggctat cttgtattaa ctgtaacgct tgtagttgat
     7261 gagaaaacgg gatctacaag tttgtcgaca aactatttag gatctcaagg attgataact
     7321 tcgtttgtca gtgcctttat tactgtaaat gtttaccgat tctgtattaa gcgagacatt
     7381 actattcatt tacctaagga agttcctggg gctatatcac aagcttttag agatattttt
     7441 cctttttctt ttgttttact tattagtggt ttgttagata ttgtatctcg ttttagttta
     7501 gatgttcctt ttgcccaagt atttcaacaa ctattgactc ctatttttaa gggggcagaa
     7561 tcatatcctg ctatgatgtt gatttggttt atgtgtgctt tgctttggtt tgttggaatt
     7621 catggaccat ctattgtctt acctgctgtt acagctttac aactgagcaa tatggaagag
     7681 aatgctcaac ttcttgcaaa tgggcagttc ccttatcatt ctttaacacc taatttcggg
     7741 aattatatcg ctgctattgg aggaacgggg gctacctttg ttgtaccatt tattttgatt
     7801 ttctttatgc ggtctaaaca attaaaatcg gtaggtaaag ctacaattac tcctgtttta
     7861 tttgcggtaa atgaacctct tctatttggt atgcctgtta ttttgaatcc ctatcttttt
     7921 gtaccttttt tgatgactcc accagtgaat gtatttctag gaaaggtatt tattgatttc
     7981 tttggaatga atggatttta tatccagtta ccttgggcct ttcctggtcc cttgggattg
     8041 ttaattggaa cgaattttca acttatctcc tttgtatttt tatctttgat gttagttgtc
     8101 gacatattga tttatttgcc attctgtaga gcgtatgata gacagttact ggtgaaagaa
     8161 gatattgcaa gctcaaatga tattatttta gaggaggata caagtgaaat aatgccttgt
     8221 gagatagatg taataaaaag taaggagttg aaagtactgg ttctttgtgc agggtctgga
     8281 acaagtgcgc aattagccaa tgcaattaac gagggcgctc aattagcaga agttagagtg
     8341 attgcgaatt caggagcgta cggagctcat tatgatatta tgggtgttta tgatttaatt
     8401 attctggccc cacaagttcg gagttattat agagagatga aggtggatgc agaaagatta
     8461 ggtattcaga tagttgctac cagaggaatg gaatatattc atttaacaaa gagtccaagt
     8521 aaagccttac aatttgtatt ggagcattac caagctgtgt agtaagtttt tccatctttt
     8581 atttgagtaa agattttgct tacagatagg cttggattta aaaacgttcc ccctttttta
     8641 atataagaat ccctctttca caattgtaaa aagagggatt ttgtatttta tctcttagac
     8701 caagttctct tcataaagag aaggaggatt gggtaaatct ccaagcgccc tgcaatcatt
     8761 gcaaaggata ggagaatttt tgagatggga ctaaagattg agaaactaga agtggttcct
     8821 agaataggcc cgatattatt gaaacagcta aagacagcgc tggtcacgac cagaaaatca
     8881 ttgctatcta ggctgacaat aaagataagc gctagcaaaa tcatagcata gatgacaaag
     8941 tacttgagaa tcttatgctg ggtatctttg tcaatcaccg ttttattaac atggagggtc
     9001 aaaacacggt ggggcgatag gattgacaaa atttggtttt tggcaatttt tgaaaggatg
     9061 aggcctcgaa taatcttgag tccacctgca gttgatccag cagagccacc gattgccatg
     9121 aggaaaagga ggataaactg ggagaagagg ggccagttgg taatatctcc atatccaaaa
     9181 ccagttgttg taatgatgtt ggaaacctgg aagaaggtca tttcaaagct ctttgaaaac
     9241 cctgggtaga ggtagagggt gttgaggcta atcaagcctg tagaaaccag tacaatgacc
     9301 aagtaagccc gaagttcttc gtcaccaaag aaggccttga tgcgacggag catgaggtag
     9361 tagtagaggt tgaaatttac cccaaaaacc agaactccga tactgaccag ataggtaatc
     9421 agtgagctgc catagtgggc aattccgtcg ttatagacgg taaagcctcc agttcccgct
     9481 gtccccatag caatgacaaa actatcgtag agaggcatac cagctagata atagatgatg
     9541 acaaagaggg agaagagagc tagataaagg agatagagaa tctgggcagt gttttttagt
     9601 ttggatacaa ccttgccaaa aacaggacct ggaacctcag ccttcatcac ctctaggtgg
     9661 ctatttttgg cattgtccat aatagcaagt gcaaaaacaa gcactcccat ccctccaatc
     9721 aagtgggtaa aacttcgcca gaagaggagg gaacggctga gaaccgaaat gtcgttcaaa
     9781 atacttgctc cagtagttgt aaacccagaa ctaatttcaa aaaaggcatc aataacgcta
     9841 gggatttgcc cagaaaagac aaaggggaga ccaccaaaga aagaccaaag gatccaacag
     9901 agggcaacga tcaagactcc ctccttggca taaatccgtt gattttttgg cttctgtaaa
     9961 ctccctgaac cgcctaacaa tacgagaatc cctatggtcg aaaagagggc tgtaaagact
    10021 tggctcgatt cacggtaata gacagcgata gccacaggaa ccaagaggag aacagcttca
    10081 atcaaaagta actttgaaag gaggtaacga atcatacttt tattcatttc ttacctcgca
    10141 atcaagtcat aaatcttggt gatgtttggc aacaaggttg ttactaggag cttgtctcca
    10201 acttccaaca tatcctcccc agttgggaaa atagtcttgc cctttcgaat aatggctgca
    10261 ataagaaccc cttttttcaa tttcagttga gaaagaggtt tggcagtcat tttattggct
    10321 tccttgatat ggaattgcag ggtttcaatt tggccattgg ctagatggtg catggcttga
    10381 aggtctgaat actgggcatt aactcgacca cgaataaagt gcataatcgt atctacagcg
    10441 atgcttttag gtgtgatgat acttgaaaaa tcaggcgcat tgataatctc gaggagactg
    10501 gtacgattga ccttagtaat atttttctgt acacctaccc tgtcaaggaa catagatgta
    10561 atcagatttt cctcatcgac acctgttaga gtcgcaacgg catcatagtg ttgagcactt
    10621 tcttccagca ggatatcttt tgcggttcca tctccttgaa cgatgtagag atttgggaat
    10681 ttctcgctaa agaagctggc gatttcagga ttgatttcaa tgacttttgt atcgatacga
    10741 ctatctttga gaataccaag tagataatag gcaattctac ctgccccaac gatgagaagg
    10801 ctcttcacgg cgcgtgattt aaaataatta tggaagagta tcatatcgac acggttacca
    10861 gtgacaaaga ttctatcttt atcctgtaca gtcatgtcac cgcttggaat gataatttga
    10921 tgatccctct ctatcgcaca gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg
    10981 ggcatttggc aaagaccgct ggtggacttg acgacaaatt ccatgaggct aacgcgtcca
    11041 ccagcaaagc gttcgacaga cagggcgttg gggaagtcaa tgatattcgc gatagcgcgg
    11101 gcagccaaga gctcaggatt aacgataaga gaaaaaccga gaatattctt ttccttgaaa
    11161 taagagttag aatattcagg gttccgcacc cgaacgatag tttctttagc tcccattttc
    11221 ttggctagaa ctgctgcaat catgttgact tcatcgtgct cagtcagggc gataaagata
    11281 tcacaatctt ggacgctggc ttgctcaaga atggcaaaat cggccccgtt accaaggata
    11341 ccaatgatat caaagcgatt gacaatatga ttgagaacag cttcgtcttg ctcaatcagc
    11401 aaaacatcat gcttttctgc aaccaaggag cgacagaggg caaaaccaac ttttccccct
    11461 ccgacaagga taattttcat aataaaacct actttttcat gatgtaacta tcataccctt
    11521 tttcaagaaa aaatgcacct actagctaat aacaagagct tttagtgaaa attcgctata
    11581 aggtaaaact ataccctaac caattgaaat agctattagc gactttctct gaaatatggt
    11641 atgataaagg atatacaagg agataaaatg aataataatt tactggtatt acaatcagac
    11701 tttggtctgg ttgatggtgc ggtatcggct atgattggag tggctttaga agagtctcca
    11761 accttaaaaa tccatcactt gacgcacgat atcacgcctt ataatatttt tgaggggagc
    11821 tatcgtctct ttcagacggt ggattactgg cctgagggaa cgacgtttgt atcggttgtc
    11881 gatccaggtg tcggttcgaa acgtaagagt gtagttgcca agactgcaaa aaatcaatac
    11941 attgtcacgc cagataatgg gacgctttcc tttatcaaga aacacgttgg cattgtagcc
    12001 attcgtgaga tttctgaggt ggccaatagg cgtcaaaaca cagagcattc ttataccttc
    12061 cacggtcgtg atgtctatgc ctatactggt gctaaactgg ccagtggtca cattactttt
    12121 gaggaagtag ggccagagct cagtgtggaa cagattgtag agcttccagt cgtagcgacc
    12181 atcatagaag atcatctggt gaagggagcc attgatattc tggatgtgcg tttcggttcg
    12241 ctttggacct ctatcacacg ggaagaattt tacaagctgg aaccagaatt tggtgatcgt
    12301 tttgaagtga ccatctatca tgctgatatg ctggtctatc aaaatcaggt tgtctatggc
    12361 aaatcatttg cagatgtgag aattgggcaa cccatccttt acatcaactc tctctatcgt
    12421 ttaggtttgg ctatcaacca aggttccttt gccaaggcct ataatgtagg tgtcggttca
    12481 tcttggacca ttgaaataaa gaaaatagaa ggataaaata ggagaatagt atggaaatca
    12541 aatttacaat taaacaagtt gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg
    12601 ggatgatcaa cattccaacc cctgttccaa atacaagcat ccagcttcag tatgcggtac
    12661 aagcgctact ttctattatt tttggaccga ttatcggttt gcttgtcggg ttgattggtc
    12721 atgcaatcaa ggactctctt gctggttatg gtctatggtg gacttggatt atcgctagcg
    12781 gactttttgg tctagttgtg ggacttttta gaaagtacgt tcgagtgatc aatggtgttt
    12841 ttgactggaa agatattctt atttttaacc tcattcaact acttgcaaat gcccttgttt
    12901 ggggtgtctt ggcaccactt ggagatgttg tgatttatca agaagcggca gaaaaagtat
    12961 ttgcacaagg gattgttgcg ggaattgcca atggtgtatc tgtagctatt gcaggaactc
    13021 ttctcttact tgcctatgca ggaacccaaa ctcgtgcagg aagtttgaaa aaggactaat
    13081 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacagtgtt
    13141 ttgagattgt
//
LOCUS       DAVBOH010000053        12976 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOH010000053 DAVBOH010000000
VERSION     DAVBOH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.053"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ873_001779"
     CDS             87..3437
                     /locus_tag="VQ873_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3108002.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ873_001780"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ873_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ873_001781"
     CDS             complement(4023..4493)
                     /locus_tag="VQ873_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3108003.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ873_001782"
     CDS             complement(4510..6783)
                     /locus_tag="VQ873_001782"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3108004.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7132..10233
                     /locus_tag="VQ873_001783"
     CDS             7132..10233
                     /locus_tag="VQ873_001783"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3108005.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YKLSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10316..11323
                     /gene="pfkA"
                     /locus_tag="VQ873_001784"
     CDS             10316..11323
                     /gene="pfkA"
                     /locus_tag="VQ873_001784"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3108006.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11382..12887
                     /gene="pyk"
                     /locus_tag="VQ873_001785"
     CDS             11382..12887
                     /gene="pyk"
                     /locus_tag="VQ873_001785"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3108007.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4022 a         2204 c         2850 g         3900 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccattttt
     7081 tataggtgaa aatggtataa tatagtgaga aggatagagg agaagtgtaa attgatcgca
     7141 caactagata caaaaacagt ctatagtttt atggaaagcg tcatttcgat cgaaaagtat
     7201 gtgagagcag ctaaagaata cggctacact catttggcta tgatggatat tgacaatctt
     7261 tatggcgctt tcgactttct agagattaca aaaaaatacg gcattcatcc tttgctaggg
     7321 cttgaaatga cagtgtttgt agatgaacag gaagtgaatt tgcgcttttt atctctatct
     7381 agtgtgggct atcagcagtt gatgaagctt tcgacagcca agatgcaggg ggagaaaact
     7441 tggtcagtcc tgtcccagta cctggaggat atcgcggtca ttgtgcctta ttttgataga
     7501 gttgagtcgt tagaactagg ctgtgattac tatatagggg tttatccaga aacactagca
     7561 agcgaatttc atcatcctat cttacctctt tatcgggtca acgcttttga aagcagggat
     7621 agagaagttc ttcaagtttt aacagcgatt aaagaaaatc taccgctcag agaagttccc
     7681 ttgcgttcga gacaagatgt ctttatatca gcaagttctt tagagaaact attccaagag
     7741 tgttttccgc aagctttgga caatttagaa aagcttattt caggcatttc ttacgacttg
     7801 gatactagtc tgaaactgcc tcgttttaat ccagctagac cagcagtaga ggagttgaga
     7861 gagcgtgctg aactggggct tgttcagaag gggttgacta gtaaagaata tcaagataga
     7921 ctagaccaag aattgtctgt tattcatgat atgggctttg atgattattt cttggttgtt
     7981 tgggatttgt tgcgttttgg acgatcgaat ggctattata tgggaatggg aaggggttct
     8041 gcagtaggca gtttggtttc ttatgcctta gacatcacgg ggattgaccc agtagagaaa
     8101 aatctgattt ttgaacgctt tcttaatcgt gaacgctata ccatgcctga tattgatatt
     8161 gatatcccag atatttatcg tccagatttt atcagatatg ttggtaataa atatggtagt
     8221 aaacatgcgg cacaaatcgt tactttttca acctttggag ccaagcaagc tcttcgagat
     8281 gtcttgaaac gctttggtgt gccagagtat aaattatctg caattactaa gaaaatcagt
     8341 tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc agtttcgtca gcaaatcaat
     8401 agtaagttag aataccaaaa agcttttgag attgcttgca agatagaggg ctatccaagg
     8461 caaacctctg tccatgcggc tggtgttgta attagtgacc aagatttaac caactacatt
     8521 cctctaaagt atggtgatga aattccactg actcagtatg atgctcatgg agttgaggct
     8581 agcggacttt tgaagatgga ctttctggga ctacgaaatt tgacctttgt ccagaagatg
     8641 caagagttgc ttgctgaaac agaaggtatt caccttaaaa ttgaagaaat agatttggaa
     8701 gacaaagaaa cgttagattt atttgcctct ggaaatacaa aaggtatctt tcaatttgag
     8761 caacctggtg ccattcgctt gctcaaacgt gttcaaccag tctgttttga agatgtcgta
     8821 gcaactactt ctctaaatcg accaggtgca agtgactaca tcaataattt tgtggcaagg
     8881 aagcatgggc aggaagaagt gactgttcta gattcagctc tggaggatat tttggctcca
     8941 acttatggca ttatgctcta tcaggagcag gttatgcagg ttgctcagcg atttgctgga
     9001 tttagtcttg ggaaggccga tattttgcgt cgagctatgg gtaaaaagga tgcctctgct
     9061 atgcatgaga tgagggcttc ctttattcaa ggctccatag aagcaggcca tactgcggaa
     9121 aaagcagagc aggtttttga tgttatggag aagtttgcag gttatggatt taatagatct
     9181 catgcctacg cctactcagc cttggccttc cagttggctt atttcaaaac gcattatcca
     9241 gccatttttt atcaggtcat gttaaattat tccaacagtg attacttaat agatgcactt
     9301 gaagcaggtt ttgaagtagc ctctctatcc atcaatacta ttccctatca cgataaaatt
     9361 gccaacaagt ctatctatat aggtttgaaa tcgattaagg ggctcagcaa ggacttggcg
     9421 ctttggatta ttgaacatag accttattct aacattgaag attttatagc taaattacct
     9481 gagaattatc tgaaacttcc tctgctagaa cctttggtaa aagttggtct tttcgattca
     9541 tttgaaaaaa atcgtcaaaa agtatttaat aacttagcta atctatttga atttgtgaaa
     9601 gagttgggaa gtttgtttgg agatgctatt tatagttggc aggaatcgga agattggacg
     9661 gaacaagaaa aattttatat ggaacaagag cttttaggga taggtgtcag caaacatcca
     9721 ctacaagcta ttgcaagtaa ggctatttac ccgattaccc caatcggaaa tttgtcagaa
     9781 aatagctatg ctattatttt ggttgaagtt cagaaaataa aagtgattcg taccaaaaag
     9841 ggtgaaaata tggccttctt acaggcagat gatagtaaga aaaaattgga tgtcactctc
     9901 ttttcagact tatatcgtca ggttggacag gaaataaaag agggagcctt ctactatgta
     9961 aaaggaaaaa tacaatcacg tgatggccgt ttgcaaatga ttgcacaaga aataagagaa
    10021 gcagttgctg aacgcttttg gatacaggtg aaaaatcatg aatcggatca agaaatttca
    10081 cgtattttag aacaatttaa aggcccaatc ccagtcatca tccggtatga agaggaacag
    10141 aaaaccatcg tttctcccca tcattttgta gctaaatcca atgaattaga ggagaaattg
    10201 aatgaaatcg ttatgaaaac gatttatcgc taaaaatacg gaaaatagaa gaattttaaa
    10261 atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa ggagcataaa ccaatatgaa
    10321 acgtattgct gttttgacta gtggcggaga cgcacctggt atgaacgctg ctatccgtgc
    10381 agttgttcgt caagcaattt cagaaggaat ggaagtgttt ggtatctatg acggatatgc
    10441 tggtatggtt gccggtgaaa ttcatcccct agatgcagct tcagtaggag acatcatttc
    10501 tcgtggtggt acttttcttc actcagctcg ttacccagag ttcgctcaac ttgaagggca
    10561 acttaaaggg attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg ttatcggtgg
    10621 tgacggatct taccacggcg ctatgcgttt gactgaacat ggcttcccag ctattggtct
    10681 tccaggtaca atcgataacg atatcgttgg tactgacttt acaatcggtt ttgacacagc
    10741 ggttactact gccatggacg ctatcgataa gattcgtgat acatcatcaa gtcaccgtcg
    10801 tacttttgta atcgaagtta tgggacgtaa cgctggtgat atcgctcttt gggctggtat
    10861 tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg aagatatcgt
    10921 agcaagcatc aaagctggtt atgaatgtgg taaaaaacac aatatcatcg tcttagctga
    10981 aggtgtgatg tcagcggctg aatttggtca aaaacttaaa gaagctggag atacaagcga
    11041 ccttcgtgta acagaacttg gacatattca acgtggtggt tctccaactg cgcgtgaccg
    11101 tgttttagcg tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag gtatcggtgg
    11161 tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg gtactgcaga
    11221 agaaggggca ttgtttagcc ttactgcaga aggtaagatt gtggttaaca acccgcacaa
    11281 agccgatatt gagctatcta gcttgaataa gagcttgtca taatttacaa tttagttaat
    11341 aagaccaaaa aggtcatata tataaaggag tcacaaaaat catgaacaaa cgtgtaaaaa
    11401 tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc ggtgaggacg
    11461 gatactgggg tgaaaaactt gatgttgaag cttcagctaa aaacattgct aaattgattg
    11521 aagctggtgc taacacattc cgattcaact tctcacacgg cgaccaccaa gaacaaggtg
    11581 agcgtatggc aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt ggtttccttc
    11641 ttgatacaaa aggacctgaa atccgtacag aattgttcga aggtgaagct aaagaatatt
    11701 catacaaaac tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa tcaactcgtg
    11761 aagtgattgc gttgaacgtt gctggtgctc ttgatatcta tgatgatgtt gaagttggtc
    11821 gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa gatgatgcaa
    11881 ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa aaaggtgtga
    11941 acatccctaa cactaaaatt cctttcccag ctcttgctga acgcgataac gacgatatcc
    12001 gtttcggtct tgaacaaggt atcaacttca tcgcaatttc attcgtacgt actgcaaaag
    12061 atgtgaacga agttcgtgca atctgtgaag aaactggaaa cggacatgtt caattgttcg
    12121 ctaaaatcga aaaccaacaa ggtatcgata acttagacga aatcatcgaa gcagctgatg
    12181 gtattatgat tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg gttccagttt
    12241 atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa agttgttatc actgcaacaa
    12301 acatgcttga aacaatgact gaaaaaccac gtgcaactcg ttcagaagta tcagacgtat
    12361 tcaacgctgt tatcgacgga actgacgcta caatgctgtc aggcgagtct gcaaacggta
    12421 aatacccact cgagtcagta actacaatgg ctacaatcga caagaacgct caagctcttc
    12481 ttaatgaata cggacgtctt gattcagatt catttgagcg taactctaag acagaagtaa
    12541 tggcttctgc tgttaaagat gctactaact caatggatat caaattggtt gtaactctta
    12601 ctaagacagg tcatactgca cgtttgattt ctaaataccg tccaaatgct gacatcttag
    12661 cattgacatt tgacgaattg acagaacgtg gcttgatgtt gaactggggt gttatcccaa
    12721 tgttgacaga tgctccatct tcaactgacg atatgttcga aatcgctgaa cgtaaagcgg
    12781 tagaagcagg tctcgttgag tcaggcgatg atatcgttat cgttgctggt gtgccagtag
    12841 gagaagctgt tcgcacaaac acaatgcgta tccgcacagt acgttaagaa aaatataaaa
    12901 acctatcata tccagctttc tagcctgtat gatgggctct ttttttgtcc agggggcaaa
    12961 actttcataa tggatt
//
LOCUS       DAVBOH010000054        12081 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOH010000054 DAVBOH010000000
VERSION     DAVBOH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.054"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            409..636
                     /locus_tag="VQ873_001786"
     CDS             409..636
                     /locus_tag="VQ873_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108008.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            924..4061
                     /gene="nanA"
                     /locus_tag="VQ873_001787"
     CDS             924..4061
                     /gene="nanA"
                     /locus_tag="VQ873_001787"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3108009.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEG
                     AIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPL
                     GTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTG
                     GVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLT
                     AFFLGLFTLGKKREQ"
     gene            5076..5528
                     /locus_tag="VQ873_001788"
     CDS             5076..5528
                     /locus_tag="VQ873_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3108010.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5547..6884
                     /locus_tag="VQ873_001789"
     CDS             5547..6884
                     /locus_tag="VQ873_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3108011.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6963..7847
                     /locus_tag="VQ873_001790"
     CDS             6963..7847
                     /locus_tag="VQ873_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3108012.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7847..8680
                     /locus_tag="VQ873_001791"
     CDS             7847..8680
                     /locus_tag="VQ873_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3108013.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8698..10791
                     /gene="nanB"
                     /locus_tag="VQ873_001792"
     CDS             8698..10791
                     /gene="nanB"
                     /locus_tag="VQ873_001792"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3108014.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10803..11906
                     /locus_tag="VQ873_001793"
     CDS             10803..11906
                     /locus_tag="VQ873_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3108015.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         4063 a         1928 c         2531 g         3559 t
ORIGIN      
        1 ctatctgcca cctcaaaacg gtgttttgag ctgactttgt cagtcttatc tacaacctca
       61 aaacagtgtt ttgagcatca tgcggctagc ttcttagttt gctctttgat tttcattgag
      121 tataaaaaca gatgagtttc tgttttcttt ttatggacta taaatgttca gctgaaacta
      181 ctttcaagga cattattata taaaagaatt ttttgaaact aaaatctact atattacact
      241 atattgaaag cgttttaaaa atgaggtata ataaatttac taacgcttat aaaaagtgat
      301 agaatctatc tttatgtata tttaaagata gattgctgta aaaatagtag tagctatgcg
      361 aaataacaga tagagagaag ggattgaagc ttagaaaagg ggaataatat gatatttaag
      421 gcattcaaga caaaaaagca gagaaaaaga caagttgaac tacttttgac agtttttttc
      481 gacagttttc tgattgattt atttcttcac ttatttggga ttgtcccctt taagctggat
      541 aagattctga ttgtgagctt gattatattt cccattattt ctacaagtat ttatgcttat
      601 gaaaagctat ttgaaaaagt gttcgataag gattgagcag gaagtatggt ataaatagca
      661 taagctgatg tccatcattt gcttataaag agatatttta gtttaattgc agcggtgccc
      721 tggtagataa actagattgg caggagtctg attggagaaa ggagagggga aaattggcac
      781 caatttgaga tagtttgttt agttcatttt tgtcatttaa atgaactgta gtaaaagaaa
      841 gttaataaaa gacaaactaa gtgcattttc tggagtaaat gtcttatttc agaaatcggg
      901 atatagatat agagaggatc agtatgaatc ggagtattca agaacgtaag tgtcgttata
      961 gcattaggaa actatcggta ggagcggttt ctatgattgt aggagcagtg gtatttggaa
     1021 cgtctcctgt tttagctcaa gaaggggcaa gtgagcaacc tctggcaaat gaaactcaac
     1081 tttcgggggg gagctcaacc ctaactgata cagaaaagag ccagccttct tcagagactg
     1141 aactttctgg caataagcaa gaacaagaaa ggaaagataa gcaagaagaa aaaattccaa
     1201 gagattacta tgcacgagat ttggaaaatg tcgaaacagt gatagaaaaa gaagatgttg
     1261 aaaccaatgc ttcaaatggt cagagagttg atttatcaag tgaactagat aaactaaaga
     1321 aacttgaaaa cgcaacagtt cacatggagt ttaagccaga tgcatcagct ccacgctttt
     1381 acaatctctt ctctgtatcc agtgacacca aggaaaatga gtactttact atgtcggtcc
     1441 ttgataatac agctcttatt gaagggcgtg gcgctaacgg agagcagttc tatgataagt
     1501 atacagatgc tcctttgaaa gttcgcccag gacaatggaa ttccgtgacc tttactgtcg
     1561 aacaaccgac agcggagtta cctcatggac gagttcgtct ctatgtgaac ggtgtcttat
     1621 ctcgaacaag tctcaaatct ggtaacttta tcaaagatat gccagatgtt aatcaagctc
     1681 aacttggagc aaccaaacgg ggcaataaga cagtttgggg aagcaatcta caagttcgaa
     1741 acctaaccgt ctatgatcgt gccttaagcc cagaagaagt tcagacgaga agccaactat
     1801 ttgaaagagg tgatttggag aagaaacttc cagaaggtgc gaaaatctca gagaaagaag
     1861 acgtctttga agggggaatg aacaacaaac caaataaaga tggaattaag agttatcgta
     1921 ttccagctct tctcaagaca gataaaggaa ctttgatcgc aggtgcagat gaacgccgtc
     1981 tccattcgag tgactggggt gatatcggta tggtcatcag acgtagtgaa gataatggta
     2041 aaacttgggg tgaccgagta accattacca acttacgtga caatccaaaa gcttctgacc
     2101 catcgatcgg ttcaccagtg aatatcgata tggtgttggt tcaagatcct gaaaccaaac
     2161 gaatcttttc tatctatgac atgttcccag aagggaaggg aatctttgga atgtcttcac
     2221 aaaaagaaga agcctacaaa aaaatcgatg gaaaaaccta tcaaatcctc taccgtgaag
     2281 gagaaaaggg agcttatacc attcgagaaa atggtactgt ctatacacca gatggtaagg
     2341 cgacagacta tcgcgttgtt gtagatcctg ttaaaccagc ctatagcgac aagggtgatc
     2401 tatacaaggg tgaccaatta ctaggaaata tctacttcac aacaaacaaa acttctccat
     2461 ttagaattgc caaggatagc tatctatgga tgtcctacag tgatgacgac gggaagacat
     2521 ggtcagctcc tcaagatatt actccgatgg tcaaagccga ttggatgaaa ttcttgggtg
     2581 taggtcctgg aacaggaatt gtacttcgga atgggcctca caagggacgg attttgatac
     2641 cggtttatac gactaataat gtatctcact tagatggctc gcaatcttct cgtgtcatct
     2701 attcagatga tcatggaaaa acttggcatg ctggagaagc ggtcaacgat aaccgtcagg
     2761 tagacggtca aaagatccac tcttctacga tgaacaatag acgtgcgcaa aatacagaat
     2821 caacggtggt acaactaaac aatggagatg ttaaactctt tatgcgtggt ttgactggag
     2881 atcttcaggt tgctacaagt aaagacggag gagtgacttg ggagaaggat atcaaacgtt
     2941 atccacaggt taaagatgtc tatgttcaaa tgtctgctat ccatacgatg cacgaaggaa
     3001 aagaatacat catcctcagt aatgcaggtg gaccgaaacg tgaaaatggg atggtccact
     3061 tggcacgtgt cgaagaaaat ggtgagttga cttggctcaa acacaatcca attcaaaaag
     3121 gagagtttgc ctataattcg ctccaagaat taggaaatgg ggagtatggc atcttgtatg
     3181 aacatactga aaaaggacaa aatgcctata ccctatcatt tagaaaattt aattgggaat
     3241 ttttgagcaa aaatctgatt tctcctaccg aagcgaaagt gaagcgaact agagagatgg
     3301 gcaaaggaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa gtattggtca
     3361 acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc acgcttcatg acccagtatg
     3421 atacaaaaac cctcctattt acagtggatt cagaggatat gggtcaaaaa gttacaggtt
     3481 tggcagaagg tgcaattgaa agtatgcata atttaccagt ctctgtggcg ggcactaagc
     3541 tttcgaatgg aatgaacgga agtgaagctg ctgttcatga agtgccagaa tacacaggcc
     3601 cattagggac atccggcgaa gagccagccc cgacagtcga gaagccagaa tatacaggtc
     3661 cattagggac atccggtgaa gagccagctc caacagtcga gaagccagaa tacacaggcc
     3721 cactagggac atccggcgaa gagccagccc cgacagtcga gaagccagaa tacacaggcc
     3781 cactagggac agctggtgaa gaagcagctc caacagtcga gaagccagaa tttacagggg
     3841 gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga tctgattcgc
     3901 ttgtaactct tactacaaaa aaagattata cttacaaagc tcctcttgct cagcaggcac
     3961 ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta acagctttct
     4021 tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat tctaaacatt
     4081 tgattttgta aaaatagaag gagatagcag gttttcaagc ctgctatctt tttttgatga
     4141 cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta gtctgttcta
     4201 taaaatatag tagattgaaa taagatgtga acaactctat caggaaagtc aaattaattt
     4261 atagaaaaat tttagcagtc aaggtgtact gttatagatt caatatatta tgcgactatt
     4321 aaccttgtct tctcctaaaa ttgactttct tgttttctta tcttgtccac tcgaaacaag
     4381 tattgtaaga atttgattat ttttgaaagt acttttaata tacttgatat agttaaaaaa
     4441 gatttgaaac taaattccaa attagaaaaa gacttgaaat actaaaaaaa aaaagtatac
     4501 tctaatcgaa aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt
     4561 aaaagttttt ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct
     4621 agaataatag attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc
     4681 ccaaatagat tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata
     4741 tcaatttcat ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct
     4801 agaaaaatca gacctccttg tgaagattga ggagatactg aatgaaaatc aaagaagaaa
     4861 ctagcaagct agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg
     4921 tatataatcc aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt ataggctaga
     4981 gagtagtgtt tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga
     5041 taggaaaaat agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt
     5101 taggaactta tgtgggagtc aatccacatt ttgcaacatt aatagatttt ctagaaaaaa
     5161 caggactaga aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga
     5221 attgctttat ttatctagca gatggtcaag caggggcttt ctttgaaaca caccaaaaat
     5281 atttggatat tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa
     5341 atgtaagcgt tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag
     5401 tggaacagtt ggttcatttg agagctggtg aatgcctcat cacttttcca gaagatttac
     5461 atcaacccaa ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga
     5521 tttcttaatg tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg
     5581 gaattgcgct agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta
     5641 gtactgaacc accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag
     5701 gaccccgttt agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa
     5761 cgaaaatcaa gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt
     5821 tagcaaatgg aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg
     5881 tcaactcaga tgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat
     5941 ttaacgaaac tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt
     6001 attcacatgc acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg
     6061 ttcctaaaac ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt
     6121 atggcttgtc tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct
     6181 acgtacgtag tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc
     6241 aacttgctca agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag
     6301 attctttgaa ttttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat
     6361 ttgactttaa ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg
     6421 attcgattga tgcttatcct attccaaaaa tcaaagagtc tgataaagac caaggaattg
     6481 aaacctcaaa cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag
     6541 cattcttaga agcactttat aatgaagaag actacgttaa attccttgat tcaactccag
     6601 taggtatgtt gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa
     6661 ctcgtaagaa gtttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg
     6721 ctattggtta tgaaaatgga ccaagtgtac aagctggtat gttgactaac caacacatta
     6781 ttgaacaaat gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag
     6841 aagcagaaaa acaattaaac gatttatttg aggctgttca gtagatgtaa aagactagaa
     6901 aataggtggg ctagtgatct gaaaagctct agcccaattt tgtaaaagaa gggagaagga
     6961 gaatggttaa agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg
     7021 taggattact ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc
     7081 atttgattat gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctatcag
     7141 atcccaactt ctttaatgcg ttctttaatt caattaagtg gaccgttttc tcattagttg
     7201 gtcaagtttt agtagggttt gtgttggctt tagctcttca cagagtacgc cacttcaaga
     7261 aattatatag gaccttattg attgttcctt gggcatttcc taccatcgtt attgccttct
     7321 cttggcagtg gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag
     7381 gtttaatgga acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg
     7441 tgtttatcaa catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc
     7501 aaacagtacc agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg
     7561 tgttcaagtt tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga
     7621 gaactgtatg gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag
     7681 ccaatgctac aacgacgctt ccaatttttg cttacaacct gggttgggga actaaattgt
     7741 tgggtcgtgc ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta
     7801 tctactttgc tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc
     7861 cagtatttat ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcagt
     7921 tttcccattg gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta
     7981 tccaacacga ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga
     8041 tttgcacttc attgataaca ttcgaaacag tttaatcatt gccttggcta caaccctcat
     8101 tgcgattatt atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg
     8161 agcaatcatg tcgagactac tcgtcattac ctatattttc ccaccaattt tgttagcaat
     8221 tccctattca attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat
     8281 ggtttatcta tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac
     8341 agttccaatt ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt
     8401 ttataaagtt gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt
     8461 tatcaatgct tggaatgaat tcctgtatgc cttgattttg attaacaata caggaaagat
     8521 gacagtagca gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat
     8581 gatggcagcg tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa
     8641 taagattgca agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg
     8701 aataaaagag gtctttattc aaaactagga atttctgttg taggcattag tcttttaatg
     8761 ggagttccca ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct
     8821 atttttcaag gaggttcata tcaactgaac aataagagta tagatatcag ctctttgtta
     8881 ttagataaat tgtctggaga gagtcagaca gtagtaatga aatttaaagc agatgaacca
     8941 aactctcttc aagctttgtt tggcctatct aatagtaaag cagactttaa aaataattac
     9001 ttttcaattt tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag
     9061 ggaataaatt atttattttc cagaccagct tcattatggg gaaaacataa aggacaggca
     9121 gttgaaaata cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt
     9181 aatggaatag aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat
     9241 ggtatagata aggcaacact aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca
     9301 aaaggaagta ttgatgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca
     9361 actattccct tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct
     9421 aactatttta gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt
     9481 gatgcacgtt atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat
     9541 agtgatgata atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat
     9601 gaggagcagt tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga
     9661 agtgcttcat tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta
     9721 ctagctgatg ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt
     9781 tttaaagaaa taaatggtca ttattattta aaactaaaga agaatggaga taacgatttc
     9841 cgttatacag ttagagaaaa tggtgtcgtt tataatgaaa caactaataa acctacaaat
     9901 tatactataa atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa
     9961 tattcggttg attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct
    10021 atgaatgttt tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg
    10081 acaactagtc agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta
    10141 ggagaaaaac ataatggaac ttacttatgt cccggacaag gtttagcatt aaaatcaagt
    10201 aacagattga tttttgcaac atatactagt ggagaactaa cctatctcat ttctgatgat
    10261 agtggtcaaa catggaagaa atcctcagct tcaattccgt ttaaaaatgc aacagcagaa
    10321 gcacaaatgg ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt
    10381 aagatagctt atatgactag tagagattct ggagaaacat ggtcgaaagt ttcgtatatt
    10441 gatggaatcc aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta
    10501 attgatggaa aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga
    10561 ggtcaattag ttgtcggttt agtcaataaa gaagatgata gtattgattg gaaataccac
    10621 tatgatattg atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat
    10681 catcacatag gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta
    10741 agcaatgtag ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa
    10801 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
    10861 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
    10921 ttgcagaaga attgggggca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
    10981 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
    11041 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
    11101 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
    11161 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
    11221 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
    11281 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
    11341 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
    11401 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
    11461 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
    11521 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
    11581 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
    11641 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
    11701 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
    11761 agattatgga aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
    11821 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
    11881 taaaattgtc agaaattgta aaataaattt tggtattctc ctattatagg tcgacttgct
    11941 cctctgaaag tacttttaga ggagctgttt gactttgcta gtttttgaaa ctgaaatcta
    12001 ttatactaca aactattgaa agcgttttaa ttttaaggta taataatctc atagaaataa
    12061 agaaaaggag gaaagaggat g
//
LOCUS       DAVBOH010000055        12052 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOH010000055 DAVBOH010000000
VERSION     DAVBOH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.055"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ873_001794"
     CDS             complement(<1..207)
                     /locus_tag="VQ873_001794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108016.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ873_001795"
     CDS             complement(275..916)
                     /locus_tag="VQ873_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108017.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ873_001796"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ873_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ873_001797"
     CDS             complement(3216..4115)
                     /locus_tag="VQ873_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3108018.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ873_001798"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ873_001798"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3108019.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ873_001799"
     CDS             complement(4747..5520)
                     /locus_tag="VQ873_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3108020.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ873_001800"
     CDS             complement(5825..6718)
                     /locus_tag="VQ873_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3108021.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ873_001801"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ873_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3108022.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ873_001802"
     CDS             complement(7281..8495)
                     /locus_tag="VQ873_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3108023.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ873_001803"
     CDS             complement(8651..8944)
                     /locus_tag="VQ873_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108024.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ873_001804"
     CDS             9106..9558
                     /locus_tag="VQ873_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3108025.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ873_001805"
     CDS             complement(9593..10981)
                     /locus_tag="VQ873_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3108026.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ873_001806"
     CDS             11047..12009
                     /locus_tag="VQ873_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3108027.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3441 a         2833 c         2198 g         3580 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctctgca aaccacgtca gcgtcgcctt ac
//
LOCUS       DAVBOH010000056        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOH010000056 DAVBOH010000000
VERSION     DAVBOH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.056"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ873_001807"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ873_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3108028.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ873_001808"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ873_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3108029.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ873_001809"
     CDS             complement(2411..2905)
                     /locus_tag="VQ873_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108030.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ873_001810"
     CDS             complement(2902..3366)
                     /locus_tag="VQ873_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108031.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ873_001811"
     CDS             complement(3376..4710)
                     /locus_tag="VQ873_001811"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3108032.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ873_001812"
     CDS             complement(4721..5338)
                     /locus_tag="VQ873_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3108033.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ873_001813"
     CDS             complement(5386..8484)
                     /locus_tag="VQ873_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3108034.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ873_001814"
     CDS             complement(8577..9743)
                     /locus_tag="VQ873_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3108035.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ873_001815"
     CDS             complement(9751..10845)
                     /locus_tag="VQ873_001815"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3108036.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ873_001816"
     CDS             complement(11003..11656)
                     /locus_tag="VQ873_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3108037.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOH010000057        11434 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOH010000057 DAVBOH010000000
VERSION     DAVBOH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.057"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ873_001817"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ873_001817"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3108038.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ873_001818"
     CDS             complement(2224..3483)
                     /locus_tag="VQ873_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108039.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ873_001819"
     CDS             complement(3485..4186)
                     /locus_tag="VQ873_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108040.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ873_001820"
     CDS             complement(4170..5369)
                     /locus_tag="VQ873_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3108041.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ873_001821"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ873_001821"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3108042.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ873_001822"
     CDS             7176..7712
                     /locus_tag="VQ873_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3108043.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ873_001823"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ873_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ873_001824"
     CDS             complement(7918..8133)
                     /locus_tag="VQ873_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3108044.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ873_001825"
     CDS             8231..8551
                     /locus_tag="VQ873_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108045.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ873_001826"
     CDS             complement(8582..8920)
                     /locus_tag="VQ873_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108046.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ873_001827"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ873_001827"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3108047.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ873_001828"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ873_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3108048.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ873_001829"
     CDS             complement(10190..10978)
                     /locus_tag="VQ873_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3108049.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ873_001830"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ873_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3284 a         2512 c         2080 g         3558 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta tattgaaact agaatagtac acct
//
LOCUS       DAVBOH010000058        11265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOH010000058 DAVBOH010000000
VERSION     DAVBOH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.058"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ873_001831"
     CDS             complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ873_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3108050.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1732..2085)
                     /locus_tag="VQ873_001832"
     CDS             complement(1732..2085)
                     /locus_tag="VQ873_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108051.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ873_001833"
     CDS             complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ873_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3108052.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ873_001834"
     CDS             complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ873_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3108053.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ873_001835"
     CDS             complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ873_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3108054.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6150..6659)
                     /locus_tag="VQ873_001836"
     CDS             complement(6150..6659)
                     /locus_tag="VQ873_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3108055.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7267..7567
                     /locus_tag="VQ873_001837"
                     /pseudo
     CDS             7267..7567
                     /locus_tag="VQ873_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7762..9600
                     /locus_tag="VQ873_001838"
     CDS             7762..9600
                     /locus_tag="VQ873_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3108056.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9613..11076
                     /locus_tag="VQ873_001839"
     CDS             9613..11076
                     /locus_tag="VQ873_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3108057.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11076..>11265
                     /locus_tag="VQ873_001840"
     CDS             11076..>11265
                     /locus_tag="VQ873_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3108058.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2206 c         2212 g         3412 t
ORIGIN      
        1 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
       61 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
      121 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
      181 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
      241 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaacta gccacgggct
      301 gctcaaaaca ctgttttgag gttgtagata cgactcacat atatacggca aggcaacgct
      361 gacgtggttt gaagagattt tcgaagagta ttattctcca tcaaaggcat cttttatatg
      421 gtcaaagaag ccttttttct ttggatttac tttcaagtca ccagcagtcg cgaattcttt
      481 caaggctact ttttggcggt cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta
      541 ttggtcacca actgcaccgc cacgaaggct cggtgccccc ttactacgta ggcggaattt
      601 cttaccagtc tgagttccct ctggaataac caattcaaca tcaccgtgaa cagttggaat
      661 atctactgta tcaccaagag ccgcttggac aaagttgagg ttgagattgt agaagatagt
      721 cgttccttca cgttcaaact tgtcgctagc ttctacagaa actactacat acaagtcacc
      781 ataaggtcca ccgttaaagc ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt
      841 ttccacacca gcagggattt tcacatgtac gctatgagct tgtttctcat gacctgttcc
      901 atgacaggtt gtacatggat atttgatttc ttttcctcga ccgtgacaga catcacaggt
      961 tacttggcga cgcatcatac caagaggagt ctgcgtatcg acgttaatga caccagcgcc
     1021 atgacagcgt ccacaagtga ctggacttgt ccctggctta gcaccagagc cattacatgt
     1081 acgacagcca gcttcacgat gatacttaac ttccttctca gttccgaaga tagcttcttc
     1141 aaatgtcaaa ttgacacgat actggagatc atctccttgg cgaggagcgt ttggattgcg
     1201 cgaagaaccg cctccgccga agaaacttga gaaaatatcc tcaaaaccac cgaagccacc
     1261 tgccccattg aaaccaccga aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc
     1321 accatactgg tcataggcag cacgtttttg gtcgtcactc aaagtctcat aggcttcttg
     1381 aacttccttg tacttgtcct cagcaccagg ctccttgttg atatctgggt gatatttttt
     1441 ggaaagctta cgataagcct ttttgatctc gtctgccgaa gcgttttttg acacccccag
     1501 acgatcataa aattcagtat tgttcataca agataccaag accgtaaaat tcgactgaaa
     1561 aataggaaat ctgacgctgg agcgacgctc ctagacagat ttctcttttt tccgagaatt
     1621 taggtcgggt tcaattcctt tcttttatat tgatgagata atactccagc cactcggccc
     1681 tatccctttt taccgaaaaa cagaggctgg gttgcaacct ctgtggttag attattcatt
     1741 tgaaataaaa atggttgtat tatctctagt agtaatcttc aaagaccttt tagctaaatc
     1801 aaactcaaat ttattatagt gtgggtcttg tgttttatat aggtgtaact cctgacatat
     1861 atgatccgaa aagtaaatca taacatcttt aaacacagaa gtgtagtcat atttactctt
     1921 accaacagct acttctgtaa attctttata aatgacattt ccatttcttt ccacagtcac
     1981 cagcatttct gttggattat aatccaaatt aaataattct tcaaaaaact ttatcttttc
     2041 atgataatct gcaatgtcag aaagattatt tttattaaca ctcataacac tagcccctta
     2101 tttttccgta aactctccgt ctacgacgtc atcgcctgcg tttcctgttg cttgtgcgcc
     2161 ttctgctcct tcttgagctt gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag
     2221 tccttgagct ttttcgttca atgcttcaag tttcgctttc atgtcgtcca agttgttgtc
     2281 ttcttgagct ttcttaaggt catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa
     2341 gcctttacct tcagtttcct tgattgtctt ttcagtcgca aagattgctt ggtctacttc
     2401 attacgaagg tctacttctt ctttacgttt cttatcggct tcagcgtttg cttctgcatc
     2461 tttcatcatg cggtcgattt cttcgtcagt caaacctgag ttcgattgga tgacaatagt
     2521 ttgttctttt tgagttccaa ggtctttggc cttaacagac acgataccgt tcttgtcgat
     2581 gtcaaatgtt acttcgattt gaggaattcc acgaggtgca gctgggatat cagtcaattg
     2641 gaagcgtcca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa gaacgtggat
     2701 atcaacggct ggttggttgt ctgctgctgt tgagaagact tgtgatttag atgttgggat
     2761 tgtagtgttg cgatcgataa gttttgtaaa tactccaccc attgtttcga taccaagtga
     2821 caatggcgtt acatcaagaa ggacaacgtc cttgacatca ccagtaatca caccaccttg
     2881 gatagccgca cccatagcaa ctacttcatc agggtttact gatttgtttg gttctttacc
     2941 agtttcagct ttaacagctt caacaacggc agggatacga gttgaaccac caacaaggat
     3001 aacttcgtcg atttctgaca agctcaaacc tgcatctgaa agggcttgac gaactggaac
     3061 ttttgtacgt tcaacaaggt cacgagtcaa atcatcaaat ttcgcacgag tcaaagtcat
     3121 ttccaagtga agaggtccag cctcacctgc agtgataaat ggcaagctga tttgtgttga
     3181 agttacacca gaaaggtctt tcttcgcttt ttcagccgca tctttcaaac gttgcattgc
     3241 catcttgtca gtagacaagt cgataccgtt ttctttcttg aattctgcta ccaagtggtc
     3301 aatgattttt tggtcaaagt cgtcaccacc aagtttgttg tcccctgcag ttgacaatac
     3361 gtcgaagaca ccgtcaccca attcaaggat agagacgtcg aatgtaccac caccaaggtc
     3421 aaataccaag attttttctt ctttatcagt cttgtccaaa ccataagcaa gagctgctgc
     3481 agttggttcg ttaacaatac gttctacttc aagaccagca attttaccag cgtcttttgt
     3541 tgcttgacgt tgagcgtcgt tgaagtaagc cggaactgtg ataacagctt tggttacttt
     3601 ctcaccaagg tagtcttcag cgtagccttt caagtattga aggatcatag ctgagatttc
     3661 ttgtggagtg tattcttttc catttgcaga aactttttca gaagttccca tcttagattt
     3721 gatagagata actgtatctg ggtttgtgac tgcttgacgt tttgcagcat caccaacgat
     3781 gatttctccg tttttgaatg agactacaga tggagttgtg cggtttcctt ctgggtttgc
     3841 gatgattttg ctttcagttc cttcaagaac tgcaactgct gagtttgttg tacctaagtc
     3901 aataccgata attttagaca tgtgtttttc tccttgttag ttaattttct atttttcttt
     3961 ttgatactct tcttaagtgg cgacgccgtc agagcttgac ttcgtcaatc tctttgacta
     4021 aactttgagc ctaaggtctc aaaatttgcg caaatagcgc cacggcgaag agtatcgtgt
     4081 ttggttcgct tcgctcacta ttacaaagcc aaacatattt tatctttctt catagtttat
     4141 tgtcgtttcg gacaagtttt ctattatgta aattgcgaca cgaagagtcg aaatcgattt
     4201 tatttcgacg acgagttagt aaggaagcta ggcaaacgcc atagcgattg ccgttttctg
     4261 acgagttgct ttagctaccg tcagaattgc cgaatcgaac acgccctaag ctctgagtaa
     4321 aaaagataga ttttcttgtg ttcatcgaac acttcgttaa tctcctattt ttactgcgag
     4381 ctttttacgg gctttgtatc ttagttatac accactacca ttgctgggcg taggatgcgg
     4441 tcatggagtt tgtagccttt ttgaaagact tgagcgatgg tatctactgg gtgttcatcg
     4501 tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc atctgctgcg
     4561 atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac catccccaag
     4621 cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag gttgtcaaga
     4681 gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt ttgacgttct
     4741 tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata tttgttttcg
     4801 aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt tgtttcttca
     4861 gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt tatatcttgg
     4921 gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga ttactgctga
     4981 ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca ttgatttgat
     5041 tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt ccaactcccc
     5101 gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag gactcttgac
     5161 cgtctgcaat acgaacattt tgcatctgat cctcacgcaa cccctcacga atctccaagg
     5221 ccaccttttg cggttggtca aagaactgat aggctgctag attggcaaaa ttcaagagat
     5281 tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg tgttcaaaga
     5341 gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga atctccgtcc
     5401 gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga atgatgctct
     5461 tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga ctagtaaccg
     5521 ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa acaacgatat
     5581 caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc gtacagccac
     5641 tcaggtctgt tagcaagtta gcagcctctt gcagaatatc ctccaatttg aagaattcct
     5701 gatcaaaggc tttgacaatc tcatatacct cattttcagc cagccggtga aaatccagtg
     5761 agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt gaagtatgag
     5821 ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg gttgcactgc
     5881 tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga
     5941 tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca tcactcctct
     6001 ctgtctgatc aattagcact caatgcatcc aagtgctaac ttatgattct attatacacc
     6061 cttagaagag aatgtcaaga caaaaactca aaaaattagc actcttttat caagagtgct
     6121 aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcggtattt cctttttagt
     6181 ctgaaataac catgaattag ataagaaatc agaaaagcat ataaaacaaa aataagaaag
     6241 aaagacatag aaagatcctc tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa
     6301 gtagctgtac aggaacgaag tctagatcgc ataacttccc atttgagccc cttactcata
     6361 tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga acaagaacct
     6421 gctcctatca attcccaacc tctatctcta aaatcttgca gttcatgctt atatttttta
     6481 agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg gtcaaaatag
     6541 aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc atgtaaatat
     6601 tcttctttct tgtccaaatc aacaatggtg aaaatccgaa attctactct gctattcatt
     6661 gtcttacccc aaaattagaa aacatgccta gcgttattta ttagataatt ctttccactt
     6721 ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca ataaaaccca
     6781 atctattatg aaaatcaaaa acacttccca actgaaagaa ctacctccag tgacaaactt
     6841 tgagaaaaac ggtagtagag ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa
     6901 aatccgtttg gcataaaaaa atctttattt aaacgaaaat attatggcaa aatttacgcc
     6961 agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat gtgattattt
     7021 atttttgaaa aatagctcac cagcccgact gaaagtgctt atagaatgat aataagtcgc
     7081 ctgccgaaaa cagcggaaaa tagcggtgtt atgcggagat aatctgacgc gatgcgaaag
     7141 tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt gatataatag
     7201 aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga atgcggaggg
     7261 ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga tattaaagca
     7321 aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca tatcgcttac
     7381 gaagaatact tcactgatgg tcgaattgag gttagaggag ataaggctcg tcgtaaagaa
     7441 ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc aattgttgag
     7501 gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga atatggagag
     7561 attttagatg ttccatttgt ttattcttca aatggtgatg gctttattga acacgaccgt
     7621 atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga agaattattt
     7681 tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat ctaaactcca
     7741 tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat agctatcaac
     7801 cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga
     7861 acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct
     7921 aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat ggctgaagac
     7981 tttaagccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac tgctcctgaa
     8041 aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg tgaagatgga
     8101 actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt aattgatgaa
     8161 gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga ttatttcagt
     8221 tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc ttccaatacg
     8281 gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga ggatggtttt
     8341 ttggctccat atcgtgttat gagggttaat ttagatgtgg atgtggatgg ttatcgtcca
     8401 gaaactggaa aagttgatac taacggacaa ttaatagaag ataggtacta cggcaggaaa
     8461 gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa gtttgtttct
     8521 gattatatga agcaaagcaa tgcacgattt gataaaacaa ttgttttttg tgttgatatt
     8581 gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt agtccaagaa
     8641 gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc tcaactggat
     8701 aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa attattaacg
     8761 acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat ccaatccatg
     8821 actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa
     8881 ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc tgattttgat
     8941 ggtgagccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc cacgcccggt
     9001 ttcgtagatg aggaaggtga cccagtagaa aaatatatcg ttacagacaa gcaggttacc
     9061 attcttaatt ctactgttca agtattggat gaaaacggga aactgattac cgaaagcctg
     9121 accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga ttttatcaca
     9181 gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa aaaaggagtt
     9241 tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga tgattttgat
     9301 ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg tatcaataaa
     9361 ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt tttggaaatt
     9421 ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga aacattaaaa
     9481 cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta ttttggagat
     9541 aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac agtagcttaa
     9601 tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat cactcgaaac
     9661 gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt attattctta
     9721 aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta tgagtcaatt
     9781 atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga acgggtattg
     9841 acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt gaaagagctt
     9901 gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt tgaagatgcg
     9961 aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt
    10021 gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa aattcttaaa
    10081 gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc gactgatttt
    10141 attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca
    10201 ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat
    10261 accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc tcatctttta
    10321 gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca tggaaatact
    10381 ttggagaaaa atgttcgtga atatacggat gatgaaaaat ttgacattat tatgatgaat
    10441 ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc agaattacgg
    10501 agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa agaaaatggt
    10561 cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg
    10621 aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc tcatagtgtc
    10681 tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac aaagaaaaca
    10741 gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt ctcgaaaact
    10801 aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag
    10861 attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt ggctgagttg
    10921 aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt aaatcccttt
    10981 gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat tgataatgta
    11041 ttagctgata ttttgcagtt gttggaggac aaataatgac accagaacaa cttaaagcaa
    11101 gtattctcca aagagcgatg gaagggaaat tagtgccgca aaatcccaat gacgaacctg
    11161 caagtgaatt attaaagaga attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa
    11221 tcaaacgaga taaaaaggaa actgagatat ttcgtggtga tgatg
//
LOCUS       DAVBOH010000059        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOH010000059 DAVBOH010000000
VERSION     DAVBOH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.059"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ873_001841"
     CDS             <1..116
                     /locus_tag="VQ873_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3108059.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ873_001842"
     CDS             140..1063
                     /locus_tag="VQ873_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3108060.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ873_001843"
     CDS             1145..2773
                     /locus_tag="VQ873_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3108061.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ873_001844"
     CDS             2882..3832
                     /locus_tag="VQ873_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108062.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ873_001845"
     CDS             3849..4700
                     /locus_tag="VQ873_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108063.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ873_001846"
     CDS             4713..6695
                     /locus_tag="VQ873_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108064.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ873_001847"
     CDS             6705..8114
                     /locus_tag="VQ873_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108065.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ873_001848"
     CDS             8119..8607
                     /locus_tag="VQ873_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3108066.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ873_001849"
     CDS             8895..9302
                     /locus_tag="VQ873_001849"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3108067.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ873_001850"
     CDS             9334..10251
                     /locus_tag="VQ873_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3108068.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ873_001851"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ873_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ873_001852"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ873_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3108069.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3693 a         1665 c         2115 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOH010000060        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOH010000060 DAVBOH010000000
VERSION     DAVBOH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.060"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ873_001853"
     CDS             complement(128..1759)
                     /locus_tag="VQ873_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3108070.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ873_001854"
     CDS             2052..6992
                     /locus_tag="VQ873_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3108071.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ873_001855"
     CDS             7082..8278
                     /locus_tag="VQ873_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3108072.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ873_001856"
     CDS             8414..8941
                     /locus_tag="VQ873_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3108073.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ873_001857"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ873_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3108074.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ873_001858"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ873_001858"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3108075.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ873_001859"
     CDS             complement(10847..10966)
                     /locus_tag="VQ873_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3108076.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOH010000061        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOH010000061 DAVBOH010000000
VERSION     DAVBOH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.061"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ873_001860"
     CDS             complement(117..1541)
                     /locus_tag="VQ873_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3108077.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ873_001861"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ873_001861"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3108078.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ873_001862"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ873_001862"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3108079.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ873_001863"
     CDS             complement(6527..7705)
                     /locus_tag="VQ873_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3108080.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ873_001864"
     CDS             complement(7785..8648)
                     /locus_tag="VQ873_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3108081.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ873_001865"
     CDS             complement(8651..10552)
                     /locus_tag="VQ873_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3108082.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3220 a         2371 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBOH010000062        10657 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOH010000062 DAVBOH010000000
VERSION     DAVBOH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.062"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(182..985)
                     /locus_tag="VQ873_001866"
     CDS             complement(182..985)
                     /locus_tag="VQ873_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3108083.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1260..2015)
                     /locus_tag="VQ873_001867"
     CDS             complement(1260..2015)
                     /locus_tag="VQ873_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3108084.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2085..4736)
                     /locus_tag="VQ873_001868"
     CDS             complement(2085..4736)
                     /locus_tag="VQ873_001868"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3108085.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4729..5307)
                     /locus_tag="VQ873_001869"
     CDS             complement(4729..5307)
                     /locus_tag="VQ873_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3108086.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5307..5867)
                     /locus_tag="VQ873_001870"
     CDS             complement(5307..5867)
                     /locus_tag="VQ873_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108087.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(5854..6303)
                     /locus_tag="VQ873_001871"
     CDS             complement(5854..6303)
                     /locus_tag="VQ873_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3108088.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6716..7111)
                     /locus_tag="VQ873_001872"
     CDS             complement(6716..7111)
                     /locus_tag="VQ873_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3108089.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7207..7461)
                     /locus_tag="VQ873_001873"
     CDS             complement(7207..7461)
                     /locus_tag="VQ873_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3108090.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7471..8805)
                     /locus_tag="VQ873_001874"
     CDS             complement(7471..8805)
                     /locus_tag="VQ873_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3108091.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8805..9038)
                     /locus_tag="VQ873_001875"
     CDS             complement(8805..9038)
                     /locus_tag="VQ873_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3108092.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9351..9491)
                     /locus_tag="VQ873_001876"
     CDS             complement(9351..9491)
                     /locus_tag="VQ873_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108093.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9488..9670)
                     /locus_tag="VQ873_001877"
     CDS             complement(9488..9670)
                     /locus_tag="VQ873_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108094.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9672..10451)
                     /locus_tag="VQ873_001878"
     CDS             complement(9672..10451)
                     /locus_tag="VQ873_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108095.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3118 a         2370 c         1974 g         3195 t
ORIGIN      
        1 aaacgaatta aggtaaaact aaaaggactt agccctgtgc aatacagaac taaatccttc
       61 ggataaatta attgtctaac tgtttggggt cagtacattt taacacttga tactatgcgt
      121 tttattgtgg gaatgtttac ttcatttttt cctaaaattc aatgtttact cagtatttgg
      181 attatgaaaa atcgaggtct aaatctagat acattttttc tgaagacaaa tcattttgac
      241 caccgagcaa gagattttca aaaaaagctg ttaaaaactc aggacgtcgc tgtaaaatct
      301 ttgcattatc taataccaag gcatcacgaa aatacttgga atgttgctga aatggtatat
      361 tatcaatatc aaaaccaaac tcacgaagat actgaatcaa aaagaccgtt actgtccgag
      421 tgtttccttc gcgaaatgga tgaatctgcc agattcctga aataaaatgc tggatttgtt
      481 taaccacatc cgcctgagtt agtgtcgcat atgcaacttg tttttcctga ttaaaatcat
      541 aatctaaggt catttgaatc atggagtaat cagagtacac aacactttca ccattcaaaa
      601 caggttcatt ctttgtgata ttggtctgac gaaattgccc caccggaata gagggttcaa
      661 atatatcttg aaacaactcc ttatgaatag caagtaaggt cgcaggacta aagctaaagc
      721 ctcttcgaga caatagttct acaatacgta gagaaaccaa gtctgcctct tccgtacttg
      781 catcaatagt atggtgataa gccgttgcat cctcataaac ctgctcataa gtcagttctc
      841 cccgggactg tttctcagcc aaagattcca tatacgctga tggcactaga ttgtcaactt
      901 tctgcagacc aaaacctatc cgccataaat cacgcttcgc ttcataagac aagtttggat
      961 tgtcaatgtt gtaagttgat tgcatagaaa tatcctttca attgtttttc ttcattacca
     1021 gtaaatcacg aaattggttg gaaactggct taaactataa aaagtcctca caataggttc
     1081 tatgatatat atatacttca tgtaaataat aaaagagtta taatcagcac tactgataaa
     1141 ttcaataccg atttcgccat cttaaaactt agtcaaacga ataccgttga tttccagttc
     1201 attaagtcgt tgacctgtca agacttctcg ttccttcaac tggaaaagtt aagggggaac
     1261 taatacaaat cctctacgct tctatattca atgatttcat tttttataat attcttttta
     1321 aactcaaaat gttttagagg attatcaact aatactaact ttggaatatc atctaggttg
     1381 gtgaccagag ataaaataaa atctgattga aactctttag ctttctcaaa ttcgtaggca
     1441 gttaaacgga cacgaccctt aggttttcga atccctttaa cttcggcaag gtaggaatgt
     1501 tcttgaatat ctacttggaa atcatatcca tcaccataaa gacatgcatc ggttaactgt
     1561 ccaccttgaa atttttcttc tttatcaaaa tgaaggataa aataattctc tgcctccatc
     1621 cccgtttcct gtagacgttt gaatttagtt cgaataattg gtttttcaat tatagtaatg
     1681 cctgtttgct ttccttcact agcaagtaac attttaacaa tttcaacata actatgaaca
     1741 tcttcatttc caaacatcat atcaattaaa tctttacgaa aacggtaaac ttcagctttc
     1801 tgccaccaac cttttcgact attgtcaaaa taaggatcaa ataaatccat tctatttttt
     1861 acaactccag ttgtttcagc aattcccaaa gaaaccacat agcgataaaa ctccgactta
     1921 ctagaatatt gaaattcttt tataaaaagc ttggcaaact tggcaagacc gtagccaatt
     1981 aaatttaaca attcataatg cgggtgttta gacatcactt tctccatcaa tagatagtaa
     2041 tttcattatc ccaaaaaaca cggcattaca ccatgtttct gtgtttattt caccaacttc
     2101 ttcatctcat caatacgtgc tacggtcgca tcatacttgg cttggtagtc agcttgtttg
     2161 tcgcgttctt tttggacgac ttctggtttg gcgttggcta cgaagcgttc gttagagagc
     2221 ttcttaccga ccatgtccag ttctttttgc catttagcaa gttccttgtc aagacgagcc
     2281 agttcttctt cgacattgag gaggtcagcc aatggcaggt agatttctgc tcctgtaatg
     2341 acgcttgaca tagccagttc aggtgcaggg atggttgatg cgatttccaa gtgttctgga
     2401 tttgtaaagc gtttgatata gttgacattg ctgttaaaga aggcttccaa gtcgctatcg
     2461 cttgtcttaa caaggatggt gataggcttg cttggtgcta cgtttacttc cgcacgcgca
     2521 ttacgaacgg cacggatcaa gtctttgaga ctttctacac cagtatgagc cgcaaggtct
     2581 tcaaaggcta gattaacagt tgggtatgca gctgtcacga tagaaccttc tgagatttgt
     2641 ccaaagattt cctctgtcac gaatggcatg attgggtgaa ggagacgaag gatcttgtcc
     2701 agagtgtaaa ggagaacaga tcgagtaatg accttatcgt cttcattgtc gctgtaaagg
     2761 acttccttgg tcaattcaac ataccagttg gcaaattctt cccaaatgaa gttgtaaagg
     2821 atatgaccag ccacaccaaa ctcgaactta tcaaagtttt cagtaacttt tgcaatggtt
     2881 tcgttgagat tgtggagaat ccagcggtcc gtcacattac cagcctcacc tgttgcaact
     2941 tttgtgacat tgtcatgcgc cacatccagc gtcaaacctt cattgttcat gaggatatag
     3001 cgagaaatgt tccaaatttt gttaataaag ttccatgaag catccatttt ctcgtaagag
     3061 aaacgaacgt cttgaccagg agctgagccg tttgacaaga accaacgaag actatctgta
     3121 ccatatttat caataacatc cattgggtca atgccatttc caagagattt agacatctta
     3181 cgtccttctt catcacgaat tagaccatgg ataaggacgt tttggaatgg ttgacggcct
     3241 gtgaattcca atgactggaa gatcatacga gacacccaga agaagatgat gtcgtaacct
     3301 gttaccaagg ttgaagttgg gaaataacgt ttaaagtctt ctgagtcaac ttcaggccag
     3361 cccatggttg aaaatggcca gagggcagaa ctgaaccaag tatccaagac gtcttcgtcc
     3421 tgagtccatc cgtcaccttc tggagcttct tcgccgacat acatttcacc atcagcattg
     3481 taccaggcag ggatttggtg accccaccaa agctgacgag agataaccca gtcgtggaca
     3541 ttttccatcc attgaaggaa ggtatcgttg aaacgaggtg ggtagaattc gaccttgtcc
     3601 tctgtgtctt ggttggcaat ggcgttctta gccaattggt ccatcttgac gaaccattga
     3661 gtagacaagc gtggctcaac tacgacacct gtccgttctg agtgaccgac tgaatggaca
     3721 cgtttttcga ttttgacaag ggcaccgatt tcttccaact tagcaacgac tgccttacga
     3781 gcttcaaaac gatccatgcc tgaaaattca aaggcaagct cattcatagt tccgtcgtcg
     3841 ttcatgacgt tgacttgtgg caagttatga cgttggccaa ccaagaagtc atttggatcg
     3901 tgggcaggtg tgattttcac gacaccagta ccaaactcag gatctgcgtg ctcatctcca
     3961 acgattggga tgagtttatt agcgattgga aggatgacgt ttttaccaat caagtccttg
     4021 tagcgcgggt cttctggatt aaccgcaacc gcaacgtccc caaacatagt ctcaggacga
     4081 gttgtagcaa cttcaagggc gcgtgaacca tcttccagca tgtagttcat gtggtagaag
     4141 gcaccttcga catccttgtg aatcacctca atatcagaaa gggctgtgcg agctgctggg
     4201 tcccagttga tgataaactc accacggtag atccagcctt tcttgtaaag gtccacaaag
     4261 accttacgaa cagcttttga caaaccttcg tcaagagtga aacgctcacg agagtagtct
     4321 acagagagcc ccatcttgcc ccattgttcc ttgatagtag tggcatattc gtctttccat
     4381 tcccagactt tcgtcaagaa agactcacga ccaaggtcat agcgggaaat gccctcacca
     4441 cgcaagcgct cctctacctt agcctgagtg gcaatccctg cgtggtccat cccaggaagc
     4501 caaagggtat caaaaccttg catgcgtttt tgacggatga taatatcttg caaagttgta
     4561 tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg gtggtggaat aacgattgaa
     4621 taaggcttag ccttttgatc gcctgaaggc ttgaaaacat cagcatcaag ccatttttgg
     4681 taacgaccag cctcaacctc ggctggattg tatttagatg aaagttcttt agacatgtgt
     4741 gtgtcctttc tctattttgt ttattttatt ttgaatttgc ttagcagctt cttctgcaga
     4801 caaattcgta ttatttattt taaagtagtg gtgcaactca ttcggttgat attgggaatt
     4861 taattgaagt gtttcagcgg tctctaaaat ttctctttca gatacctcaa tatgtcgttt
     4921 taagggtttg tgctttaatc gattctccgt tcgatttcga cgtatgcact cttcaagact
     4981 tgtttccaac tcaacaaaaa gaatctcttg atgataatca tccaacaaat tctgaatttg
     5041 ctttaaatat atcagatgat actgatttga aaaatcaatt acatctgtta aaattactga
     5101 tcgctgattt cttgcacttg ctccaaggaa tgaaaaagtg attccacgaa caaattccca
     5161 catttcctct gtatagtcct gatagatttc tagtgcaaaa tcaatggctt gatggttata
     5221 aaatagggta gcatccgtca gtcgagataa ttcttgacca atggtcattt ttcctgatgc
     5281 tggagcacca atgatgaaaa gatgcatcaa atcacccccc actcactctt cagcaaggca
     5341 tatctcaaat catcacagca gttgccttga gcatctttac ggtctcttat gcgagcttcg
     5401 agggtaaagc caagcttttc cgcgactcgt tgactttgaa ggttatatcc aaagcaagtt
     5461 agttcaatct tgtgaagacc caaatcttta aaggctaagt caatcaaggc acgcgcagct
     5521 tctggcacat aacctcgccc ccaatagtct gagtgtaagg tatagccgat ttccatcaca
     5581 tcatcttcat ggcgatggtt gaaatagata gagccaacga tcttatccgt tcctttgacg
     5641 acaatcccgt agcctgctgg gagattttcc ttttgattac gctccggaag aatgtgctcc
     5701 agataataaa tctcatcttc caaggtcttg actggaggaa aacctgctgg ataggcgacc
     5761 tctggcaaac tagcatagtc aaagatatcc tcagcatccg ccacagtacg gactcgtaaa
     5821 acgagacgtt ctgtttcgat tttatctggc agctcagttc ttgccatcct tcttcctcgc
     5881 ttttttgatg aaactgccct tcatatctac acgcttgtcc agatagcgat aaacgcgctg
     5941 atatccatct cccatgaaat aggttggggc aaacagttga tttttaaaat gtcccttttc
     6001 atccaggagt tctggggcaa caagtcgctc aagaatcttg gcaaagatgt ggcaaatacc
     6061 gtcttcctca acaatcctat ctacccgaca atctaaaaca agtggacagg cgtctaaaat
     6121 aggagtctga gttcgttcag aaatttcata atgcactccc aaacgttcca atttctcctg
     6181 atgactgata aaaccagcct gctccatcgc aagcatagaa gtttcatcag aaatattcac
     6241 agtaaatttt tgatactgtt tgatctgctc tgcggcattc tctctcgcaa cgactccaat
     6301 cacaacccaa tctcctagac tataagagga actacaggtc gtgatgttat agccaaaatt
     6361 ctaatcttga tatcctaaaa taaaaacagg aaaaccataa tatagtttac ttgtgttaaa
     6421 agattgcttc ataacaaccc cctttgacta agacgtaaaa gaaaagccct gccatctaca
     6481 tgacagggac gaatgtgttt atccgcggta ccacccaatt tcgggcagtt gcccgcaact
     6541 ctcgtcttta aagcaaaaag acacttttat ttcaattttt catccattag caaccagttt
     6601 tgacacattt gtggacttct cagcgccgcc actttctgta aaatgtggga ttcaaaacac
     6661 ctctaatggc tctattgtag caagattttt tcggaaatgc aaggctcaag aaaaattact
     6721 tgaacttgat gccattttct ttcaatttct tgatggtagc tgggccgatt cctttcaagt
     6781 caaggagttc tttttcagtc cagtttttga aatgtgaagc agacttgatt ccttcatcat
     6841 agaaagtctt ggcacgatca agtggaagtc cacccaaatt tgctgcaaaa tcttctacag
     6901 aattagctac tttttgagct tgctctttgg tagcttctac tgcttgttca acttttttag
     6961 aaacagcctt accagctgcg cttgctgtct gttctgcacg cttcacgact ttttttgtct
     7021 catctacaac cttagtcaca gtacttgaaa aggcacctgc gcgacggagg ccatttcgta
     7081 attgtttttt acgattgagt ttctttgaca tgataaaatc ctttcaataa aaaatccctg
     7141 ctctgacaag gatttaacat aaacattcta tcaagatttt agtgaaaaat caagaatctt
     7201 tctcgtttaa taatttcgct caccaaacaa gccttctggc aaatcatgga atcccttgcc
     7261 tactttgaag ttttcaaact taccaagcaa gaactgataa gcatccaagc gactctcgta
     7321 gcgaatcatg gcatctttgg cacgctcgtc ctggtcttct tcgtaaactt tttgactttc
     7381 cttgtgcgcc atatcgttaa tcatgatttg ggtattgacc caagcttcaa attccttcat
     7441 aaattcttgt tcgtaactca ttttttctcc ttattctaat ccacgaaaat agtccgtatc
     7501 aatctcacgg tagggctgga tatcctgaac atactccaac actccttgga attctccgtc
     7561 ttcatcgtgt actgcagcat aggtgatgtg gacaaactta cctcgcgact cagacttgaa
     7621 ccacatttca tacttgtcct tggtcccctc acgaagtccc ttcatgatag ccttgacctt
     7681 gtccaaatac ttaggcggat gacagagttc gacattgcgc ccgacttggg acggcgtccg
     7741 tttgaaaatc atctcatcag ctggcgtatt gtcattgtaa tactggaaaa tatcttcttt
     7801 attgacaaag gtaatctcca tagggagatg attgaggatg agattggcct gctcgactga
     7861 aagatagcca ttaccaaaag cctgttgact atggcggtcc agcacagctt ccttttcctt
     7921 aggggtaaag gtaatggtaa aatggccttc tggcgtatct atgacttgtt gaacttgacc
     7981 ttctgccgta tctagttgta caggctcctc tgcaatcttt tcctcaataa agatctgtcg
     8041 ttctggcacc catttctctg acggacggat gatggcatag ccataggcat cactctcctc
     8101 cgcaatctga agccagtcat cctgagtaaa agactcaagg agaatcatga gcaggatgga
     8161 ctcttccttg aaaatcatac tttcaaactc tgtcgcaaaa gcttcaaaag cttcctttac
     8221 actgctaatt gacacttctg gtagtgactt ggctgtcgtt agagctgttt gaaagagttc
     8281 cctaatctga tcatccactc cccacataac tttgggaggt gaatcgtgtc catagcgctc
     8341 catgatagga aagaagagtt cttccttacg ttggtaatgg atgtcaaatt gacccacaag
     8401 tcccatctga cgcaccaaac ccttacgcat ctccgccagc atttcctcgt cttccataga
     8461 ctcataggta tctaacaatc tacgaatgcg aatcaaggcc gcacggagag ccagattttc
     8521 ttctttgaag acacgaactg ggtgacctgg atgctcagta tctgaaactt cgacaccttt
     8581 gatagcattt ttaaaaagat tggcatggac atcacagagt tccataacat cttcaaaagt
     8641 gacgcccgaa tccgagttca tcagctcgtg ctccataagg gaaatctcaa tggctgagac
     8701 acccgcaaag gtcgcatcaa aacgctcctg aaccgactca ggagaggcgc cattatgcaa
     8761 ttctaataaa atatcccgta ggacatgaat ccgttcatct gccattagtc taatccaatc
     8821 acttcgtagc cattcgcttc cagtgtgcgt acaatcttgt ccataggagt tcctgctagc
     8881 ttagaaccct gtttaagtga tactttacga ccaactgtat tgcgcattaa gggattggca
     8941 aggggtttaa aacccaactc cactagaatt tccaagactt ctggatgctt gtccaccact
     9001 tctgcaacag gaattgacac atcgatgata ttgtccatga cgacctccat tatatgttct
     9061 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacagt
     9121 gctttgagat tgtagataga actgacgaag tcagctcaaa acaccgtttt gaggttgcgg
     9181 atagaactga cgaagtcagt aacatatata cagcaaggtg aagctgacgt ggtttgaaga
     9241 gattttcgaa gagtataaaa tgattttact gcttatatta taccatatgg aaagagaata
     9301 aaaaactagc agtggagttc ctgctagttc tctgcgactt ggattaccat ctagataagt
     9361 ttaaagaacc aatccaatat cttgtaaaac agcaattgga ctgcaaaaga gatgatcatc
     9421 caaaagaatt tcacaatccc aataatcggt ttgataaaaa taatggcaag aagtccccag
     9481 aaaaatttca ttttttatcc tctggcttaa tgagccaccg agccgtatcc attaacttgt
     9541 cggcaataaa aagtttcccc agaccgacaa cggcattatc atctttcttt atcgttttca
     9601 ttacttttac accttgcacg gtcaaaaagt aattaccata aattttagca aaagctttga
     9661 taggattcat attactctcc tttgatgatt tcagcctctt ttcggattgt ttcaacatct
     9721 tcttgatatt gaacttcact atagttgact agcttggata attctttctg caagctttcc
     9781 cccattggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc caagatagga
     9841 ataaatttcc ccattccttt ggccagccct cccttggtaa gattcacacc aaatattctt
     9901 aagactttct tcaaaatagg ataccaaagc gtctttgtta aagctttatt aggtactgtt
     9961 ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaagcagc agttccattc
    10021 acccccaaca tgacgcctag ataaagcaaa agggtatttt gagcatcttc actcaactca
    10081 tcgcgtgaag cccaaagatc ctcataacca taaatataac ctaattcttg ggccaatttc
    10141 agagagaaac cataaaattg agccacatca gctggaatgg taattgccat agcaagccct
    10201 ccaggtaatc ctgccaaaac agaagtccca ctcgctaata aaacattatc cctaatacag
    10261 gcattagcca ctcgatctaa gatttcttga gataagagag acgttggacc ttgttccaat
    10321 aaggtaggaa tgtcctgtgg acccaattct ttggaaaact tatccactaa aaatttcgaa
    10381 cgatcaacct taacaacagg tagtttcacc acttgttgca atacttgcat agctaagtct
    10441 tgttcagcca tatacaaact ccttatttct tttttgcacc ttatcatatt atatttccta
    10501 caaaaaaagc attttctaat tagataacat taaaaaatac agaacccctt ttttatagta
    10561 aaatgaaaca agaacaggac aaatcgatca ggacagtcaa atcgatttct aacaatattt
    10621 tagaagtaga ggcgtactat tctagtttca aactatt
//
LOCUS       DAVBOH010000063        10628 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOH010000063 DAVBOH010000000
VERSION     DAVBOH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.063"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            393..1571
                     /locus_tag="VQ873_001879"
     CDS             393..1571
                     /locus_tag="VQ873_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3108096.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1885..2016
                     /locus_tag="VQ873_001880"
     CDS             1885..2016
                     /locus_tag="VQ873_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3108097.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2037..3587
                     /gene="dltA"
                     /locus_tag="VQ873_001881"
     CDS             2037..3587
                     /gene="dltA"
                     /locus_tag="VQ873_001881"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3108098.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3584..4828
                     /gene="dltB"
                     /locus_tag="VQ873_001882"
     CDS             3584..4828
                     /gene="dltB"
                     /locus_tag="VQ873_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3108099.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4842..5081
                     /gene="dltC"
                     /locus_tag="VQ873_001883"
     CDS             4842..5081
                     /gene="dltC"
                     /locus_tag="VQ873_001883"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3108100.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5074..6342
                     /gene="dltD"
                     /locus_tag="VQ873_001884"
     CDS             5074..6342
                     /gene="dltD"
                     /locus_tag="VQ873_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3108101.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6497..6937
                     /gene="adcR"
                     /locus_tag="VQ873_001885"
     CDS             6497..6937
                     /gene="adcR"
                     /locus_tag="VQ873_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3108102.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6937..7641
                     /locus_tag="VQ873_001886"
     CDS             6937..7641
                     /locus_tag="VQ873_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3108103.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7634..8440
                     /locus_tag="VQ873_001887"
     CDS             7634..8440
                     /locus_tag="VQ873_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3108104.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8450..9955
                     /gene="adcA"
                     /locus_tag="VQ873_001888"
     CDS             8450..9955
                     /gene="adcA"
                     /locus_tag="VQ873_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3108105.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMANWPTYYPDNLSGQEIAQEMLAH"
BASE COUNT         3057 a         2004 c         2251 g         3316 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aactaacttc ttagtactag ccaacaacga
      241 taatcataat tcctcctaaa attaggaata ataaaggcaa tagtttttgt tttttcatgt
      301 aaaaaacctc acttttgttt tctgctattt tatgctaaaa tattaaaaat caaatttaat
      361 tccaaagttt gtaactaaag ggggagcgct acatgtctaa ttcatttgtc aagttgttag
      421 tctctcaatt atttgcaaat ttagcagata ttttctttag agtaacaatc attgctaaca
      481 tatacattat ttcaaaatca gtaattgcca catcactagt tcctatctta ataggaatat
      541 cctcttttgt tgcgagtctt ttagttccgt tggttactaa aaggttagcg ctaaataggg
      601 ttttatcttt atctcaattt ggaaagacta tattattggc gatactggta ggaatgttta
      661 ccgtaatgca atccgtagcg cctttggtga cctatctatt tgttgttgca atttccatac
      721 tagatggttt tgcagcaccc gtttcctatg ctattgtgcc acgctatgcg accgatttgg
      781 gtaaggctaa ttcagcctta tcaatgactg gtgaagctgt tcaattgata ggttggggat
      841 taggtggact cttgtttgca acaattggtc tgttacctac cacgtttatc attttagtct
      901 tgtatatcat ttctagcttt ctgatgttat ttcttcctaa cgctgaagtg gaggtgttag
      961 agtcagaaac taatcttgaa attttgctca aaggttggaa gttagttgct agaaatccta
     1021 gattaagact ttttgtatca gcaaatttat tggaaatttt ttcaaatacg atttgggttt
     1081 cttccattat acttgttttt gtaacggagt tattaaataa aacggaaagt tactggggat
     1141 attctaatac agcatactct attggtatta taattagtgg cttaattgct tttaggctat
     1201 ctgaaaagtt ccttgctgct aaatgggaaa gtattctttt tcctcttgta gctatggcaa
     1261 tagtgacact gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt
     1321 tagttggtat gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag
     1381 tagaggaaaa tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat
     1441 tttcagtatt tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt
     1501 tttggctatc agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt
     1561 attttaaatg agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg
     1621 tgttgaaaaa acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg
     1681 aaatggagtt ttgaggcagg atcactctat ttgaaaatat acatagaaaa actgtataat
     1741 ccttaaaata agctgaaatc tattggaaac atacggtaaa caattgaaaa gatactatat
     1801 aaagtggtac aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat
     1861 tacagaaatg aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt
     1921 cggacagcct tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt
     1981 cagggtcaag gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt
     2041 caaataaacc aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta
     2101 gctatcctgt ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt
     2161 cggatagttt ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg
     2221 tttttggtgg ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc
     2281 atgcctacat tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag
     2341 tagcagagcc aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac
     2401 caatgataaa tctagctcag gttcaagaag cctttgccca agggaataac tatgaaatca
     2461 cgcatccagt caagggagat gataattact acattatctt tacttctggt acgactggta
     2521 agcctaaggg agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta
     2581 cggataagga atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt
     2641 ttgacttgtc tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc
     2701 ttccttcagt catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa
     2761 tcgctatctg gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca
     2821 acagtgagaa aatgcctgga atcacgcatt tctactttga tggtgaagaa ttgacggtca
     2881 aaacagctca aaaactgcgc gagcgtttcc caaatgcccg tatcatcaat gcttacggcc
     2941 caacagaagc gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc
     3001 tcaaacgcct accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg
     3061 aaggaaataa actgccaaat ggtgagcagg gagaaatcat tgtttctggg ccagctgttt
     3121 caaaaggtta tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaagatc
     3181 tgccagccta tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg
     3241 gcggacgcat ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct
     3301 ctcaaaacct caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca
     3361 aggaccacaa ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc
     3421 agtttgagcg agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga
     3481 tgtcctatat gatgccatct aaattccttt accgagacag tttgccacta actccaaatg
     3541 gaaagattga catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca
     3601 acagcttcct catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc
     3661 aaccttgccc atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt
     3721 ggtaagtctc ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc
     3781 cttgggtatt tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa
     3841 aagcaaggat ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat
     3901 ctttgtcaag gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat
     3961 ttcttacctt acctttcgtt cggttgggat tgtcatcgag ctgagagatg gagtgattaa
     4021 ggattttacc ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg
     4081 tccaatcgat cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga
     4141 gttgatggat atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt
     4201 tatcctagct catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca
     4261 gtcaggtggc ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggaact
     4321 cttctttgac tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat
     4381 ccgtagccct atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa
     4441 tcgctggcat atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat
     4501 ggtgttaacc agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat
     4561 tgtaaatatg ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg
     4621 actctttcat ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct
     4681 caataaggaa cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt
     4741 gcttggcatg gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt
     4801 cttgaataat ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag
     4861 ttattgaaat tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc
     4921 tttttgatgc aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga
     4981 accgttttga cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta
     5041 ataaaatcat agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc
     5101 ggaccggtct tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag
     5161 atgcatcata atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt
     5221 aaggagcgaa gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc
     5281 tttggctcta gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa
     5341 tacaatcgtt cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa
     5401 tattttggaa tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc
     5461 tcacctcagt ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat
     5521 ggagaccagt tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca
     5581 gcgactcgct tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg
     5641 gcaagtaaag aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt
     5701 aatgaacgcc aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat
     5761 aagcatgtag ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa
     5821 gatgttgtca aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat
     5881 tatttctata atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc
     5941 tttacctatc tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct
     6001 aaatctaagg taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat
     6061 gctggtctac gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttggaa
     6121 agtcaaggtt ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg
     6181 aaggacacca ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct
     6241 ttcctatcca atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa
     6301 gattgggcga cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga
     6361 gttcaagaat gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa
     6421 ttaactggta aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa
     6481 aggaaaggag tcagatatga gacagctagc aaaggatatc gatgcttttt tgaatgaggt
     6541 gattttgcag gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc
     6601 cctgaccaat actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc
     6661 agaattggcc cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt
     6721 ggtcaaggaa gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta
     6781 tcagttgact gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac
     6841 acttttaacc tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca
     6901 gcggtttttg actgctttag taggagaaat caaataatga gatatattac ggtagaggat
     6961 ttgtccttct attatgataa ggagcctgtt cttgaacata tcaattattg tgttgatagt
     7021 ggggaatttg ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggct
     7081 agtcttggaa ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa
     7141 ggtaagaaat tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt
     7201 ccaagtacgg tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt
     7261 cgtttgaatg ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg
     7321 gaacatcgag acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtgatt
     7381 gcgcgtatgt ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg
     7441 gatgcaggaa gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc
     7501 aaggctgttt tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat
     7561 attcatctag tccgtaacca agactcgcca tggcgttgtt tcaatgttca tgagaatggc
     7621 caggaggtgg gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc
     7681 ggttattgct atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca
     7741 gagtttgatg agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt
     7801 tttggggatt tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct
     7861 ggagtatctc cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc
     7921 aacaggtctg gctgtttctc tgattgtcat gagcaagggt aaaagctcga gttcaatgag
     7981 tttggaccaa tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct
     8041 ctttgtcatt gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat
     8101 cttaactttt gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat
     8161 tctttttaac atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct
     8221 tctggtatcg accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt
     8281 taaatcggtt atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta
     8341 catttcctac tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt
     8401 ctttatacta atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat
     8461 tagcttatta ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca
     8521 ggcagatggt aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca
     8581 agtcgcagga gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga
     8641 atacgaacca tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga
     8701 aaatgaaaac atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt
     8761 gaaaaccatc aaggcgacag gcgatatgtt gctcttgcca ggtggcaagg aagaagaggg
     8821 agaccatgac catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc
     8881 accagttcgt gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc
     8941 tgataaaaaa gagacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt
     9001 ggataaggct tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca
     9061 cgcagccttt aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact
     9121 ttctccagat gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa
     9181 aaataaaatc gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact
     9241 ttcaaaagaa gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga
     9301 ggacaccaag gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa
     9361 acaaacaaca gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac
     9421 agtccaaaat ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc
     9481 aggtaactgg caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga
     9541 ctacaaggct aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa
     9601 aggctatcag acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca
     9661 aggtggacaa agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa
     9721 gaaaggcaat cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt
     9781 caagtatgtt cagtttagtg accacaatgt tgccccagtt aaggcagaac atttccatat
     9841 cttctttgga ggcacaagcc aagaagccct ctttgaagaa atggccaact ggccaaccta
     9901 ctacccagat aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga
     9961 aatcgactag ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata
    10021 gacctttcag aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag
    10081 aatgtagtta gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta
    10141 agggcttttt tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct
    10201 acttcttacc atctagccat ttgcagacga aatacaagat aattccagct ataacatctg
    10261 ctataatagt aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac
    10321 ccataggaac gtaatcggta accgatgaca aaagtattat atcacactaa atttagatca
    10381 tcaacctcac ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata
    10441 aggttcatta gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta
    10501 tcttagcgat ttaacgggtg tttataggct agtcactcgg tctacttctt actatctagc
    10561 catctgcaga cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg
    10621 agctctat
//
LOCUS       DAVBOH010000064        10492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBOH010000064 DAVBOH010000000
VERSION     DAVBOH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.064"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(26..628)
                     /locus_tag="VQ873_001889"
                     /pseudo
     CDS             complement(26..628)
                     /locus_tag="VQ873_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(1214..1990)
                     /locus_tag="VQ873_001890"
     CDS             complement(1214..1990)
                     /locus_tag="VQ873_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3108106.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2112..2858
                     /locus_tag="VQ873_001891"
     CDS             2112..2858
                     /locus_tag="VQ873_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3108107.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2871..3851
                     /locus_tag="VQ873_001892"
     CDS             2871..3851
                     /locus_tag="VQ873_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3108108.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4046..4366
                     /locus_tag="VQ873_001893"
     CDS             4046..4366
                     /locus_tag="VQ873_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3108109.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4412..4720
                     /locus_tag="VQ873_001894"
     CDS             4412..4720
                     /locus_tag="VQ873_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3108110.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4737..6035
                     /locus_tag="VQ873_001895"
     CDS             4737..6035
                     /locus_tag="VQ873_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3108111.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6186..8624
                     /locus_tag="VQ873_001896"
     CDS             6186..8624
                     /locus_tag="VQ873_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3108112.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8643..9311
                     /locus_tag="VQ873_001897"
     CDS             8643..9311
                     /locus_tag="VQ873_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3108113.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9329..10417
                     /locus_tag="VQ873_001898"
     CDS             9329..10417
                     /locus_tag="VQ873_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3108114.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3437 a         1487 c         2087 g         3481 t
ORIGIN      
        1 aatttgtcct gttcttattt cattttacta taccatcaat aagtgtgaaa agatctttta
       61 cataagacca agccttatta tctttgtaac caccttgagc ttgtagcata tttgttaatt
      121 gagcaaaggc gctagaagag tttgctgggt cagcagttgc gatttttcct tttagttcag
      181 gtttgagaag gtcgctatat ccttcgatgt tcatgccttt agttaaatca gggtggacga
      241 ttaaaacact accatctagt gtataaggag tagagaagcc agttgtgttt tgatattctt
      301 tgataacatt atcattttct tttgaaatat agttttcaaa gagttctccg tgggtagcat
      361 attgtgtata agaaccacca aagataacat cagctacagg aacttctttt tctgactcta
      421 gttttttgaa aagttctcca gtaccagctt gaatcagttc tattttgata ccatattttt
      481 cttcaaaggc aggaatagtt gctccaatta agccttctga gtttggtgaa taaacgacta
      541 gcgaaccacc gtctccttta tcagatgaac tgtcatcggc agattcatta gaagaacaag
      601 cagcataata catccatttc tttttcatga tggatacctc cgttgtgtta tttaagttta
      661 ttttaaaaca atgtaagcgt ttttaaaacc tacaattcta ttctatagtg tattgaatct
      721 ataacagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
      781 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaaaaagaa
      841 tagcctattt tactattttt ccgagtgatt tcaattcctt tggggaaata tggagatact
      901 ttttaaatcc tgacaaatgg ttgtttcttt ttctaaatcg gtgatactgt atcggagaat
      961 gcgcgtgagg tcacaaaggc tgcgatagag cttctatgga gaatttcttt ttggagagat
     1021 tttttaaagg aatgagacat ccgctacctc cttggaaggt tttttgtgat aagtatagca
     1081 gtttaaaaat tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa
     1141 ccttttgaaa agttaagtat gtattataga tgcttgttat ctgcaaatat ctagagcatt
     1201 tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat
     1261 caataagatc ttcaggatga agtgcgttga ctccatccat ttcatatttc cgatttaata
     1321 aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta
     1381 atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa
     1441 taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa
     1501 taatcatttg attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta
     1561 ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa
     1621 aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt
     1681 tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt
     1741 cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt
     1801 caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt
     1861 gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg
     1921 tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag
     1981 atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa
     2041 acaattacga acgaaaggtt aatttgttgt tttttgcttt ttattttggt agaataaaac
     2101 ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga
     2161 tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt
     2221 tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata
     2281 gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc
     2341 aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct
     2401 gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt
     2461 cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg
     2521 gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga
     2581 cttttcatgt gcgtcaagct tttgttggga cagatggcta cgataaagag atgggcttta
     2641 caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag
     2701 tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt
     2761 taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat
     2821 tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaagtgt atgaatcaag
     2881 ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt
     2941 cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag
     3001 caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt
     3061 tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat
     3121 ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtgtcctta
     3181 ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt
     3241 tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg
     3301 gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa
     3361 aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag
     3421 cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag
     3481 atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca
     3541 tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt
     3601 gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag
     3661 caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata
     3721 cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag
     3781 acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc
     3841 taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac
     3901 atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta
     3961 tgtagttgta ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt
     4021 tacatagtga aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg
     4081 tttaatttta tatgctggcg atgcgaaaca acatatttat aaagcattag attacataaa
     4141 gaacggtaca tgtgaacgat gtgaagaaga aatccagtta gctgatgccg ccttattaga
     4201 agctcataat ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat
     4261 tacagctctc tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt
     4321 aatcaaagaa attattagtt tgagaaaaga acttcataaa aaataatact agagtattat
     4381 cattgttatt aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc
     4441 aggtttttct actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt
     4501 tgaggcagaa atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga
     4561 tgttgcacta ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga
     4621 taagtgtgat gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa
     4681 aaaagtatta gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt
     4741 caaagatgga tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca
     4801 ttatagctct aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttgt
     4861 tcttgattat gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg
     4921 gagctaattg gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc
     4981 taatttcttg tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac
     5041 cagctggagt tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta
     5101 aacaaggtga ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta
     5161 tcggtgctat cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa
     5221 aaattgttat taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa
     5281 tgattccagc atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat
     5341 tgactaatgg cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag
     5401 gtttaactgg atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt
     5461 ggtttggtgt tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta
     5521 atcttgacgc taataaagct atgttagcct ctgctaatct atcattagaa aatggtgcac
     5581 atattgttac tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt
     5641 ttggtcttgt agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa
     5701 aagttgcagc ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga
     5761 ttgtcatgaa tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga
     5821 tagtatatgg agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt
     5881 ggagtacacc agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc
     5941 agttattagt attggtgata tctacagtgg tttactttcc attctttaag atacaagatc
     6001 gtttagctta ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac
     6061 tcacacattt gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt
     6121 tctataaaaa tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc
     6181 ttacgatggt aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc
     6241 ttactgaaag gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg
     6301 ctgagagagc agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc
     6361 taaaacgtgc atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag
     6421 aatctatgat tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat
     6481 atacgctaga atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt
     6541 tctatattac agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata
     6601 ataatttacg tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa
     6661 caggattctt cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact
     6721 atcagaaact tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag
     6781 tagctctaga tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat
     6841 ttattgtaat cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt
     6901 tagccgaaaa tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct
     6961 ctagagtccc atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta
     7021 ttcaatgtat tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc
     7081 aatatatgta tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca
     7141 ttgttgaacg tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc
     7201 aatcacatac attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac
     7261 agactcgaga taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg
     7321 cacaaaccca tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc
     7381 gtttcatgaa tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata
     7441 atgatgagat tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg
     7501 attacagtgc cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca
     7561 caggtatgag ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg
     7621 atccggcttc gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact
     7681 tttctgaatt agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta
     7741 ttgttgaaaa ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag
     7801 cattgactga tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg
     7861 attatatatc aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta
     7921 aaaaattggt gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa
     7981 cagattatgc cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta
     8041 agtatggtaa tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg
     8101 ttgatgaaat tgctaaatat cctaatacac gttatggaag agggcctatt ggaggaattc
     8161 gttattcagg aacatcttct atatcagcca acgtagggca gggacgtgga acattagcaa
     8221 ctccagatgg acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata
     8281 tggatcaaca cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa
     8341 tcgtaggtgg ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag
     8401 ataaattaaa actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata
     8461 ttcaatacaa tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac
     8521 acagagactt aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg
     8581 caacccaaga tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt
     8641 ttatggaatt tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt
     8701 tgccgctagc tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt
     8761 tttttgaacg aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc
     8821 aggtgatttc tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag
     8881 caggagatga tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg
     8941 tgctaaaaaa agagggctac catatcactg caacagctat ttatacagtt attcagggat
     9001 tattagctat cgaagtagga gcggattacc tagctccata ttataataga atggaaaatc
     9061 tgaacattga ttcaaattct gtcattcgtc aattagctct tgctattgat agacagaact
     9121 ctcctagtaa gattttagct gcatccttta aaaatgtagc acaagtaaat aatgctttag
     9181 ctgcaggtgc gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc
     9241 catctatcca aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc
     9301 gttccattta gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat
     9361 tcagggggaa aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc
     9421 gattctatta tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct
     9481 acataggtat ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga
     9541 aatcaatcga gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg
     9601 tgggggaaag acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat
     9661 tattgctcca acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac
     9721 agatgaaggt gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt
     9781 tgatacaaaa gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg
     9841 tttagcaact tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg
     9901 acaacagcaa acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc
     9961 agatggttta caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa
    10021 tattgttgaa gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc
    10081 ggcgcatgca attcataatg gttttactgc attgacaggt gacattcatc atttaacaca
    10141 tggtgaaaaa gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga
    10201 agaacttgat aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga
    10261 aatgcatttg gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat
    10321 ggagggtgag acaattcatc agatgccgtt taagatttcg ccctcagatg ttgctcaagc
    10381 tattatcgct gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca
    10441 aatggtagtc ttttattgat ccctgtattg aattctatag cagattgaaa ta
//
LOCUS       DAVBOH010000065        10491 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOH010000065 DAVBOH010000000
VERSION     DAVBOH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.065"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            156..368
                     /locus_tag="VQ873_001899"
                     /pseudo
     CDS             156..368
                     /locus_tag="VQ873_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            268..714
                     /locus_tag="VQ873_001900"
     CDS             268..714
                     /locus_tag="VQ873_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3108115.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(852..2156)
                     /gene="eno"
                     /locus_tag="VQ873_001901"
     CDS             complement(852..2156)
                     /gene="eno"
                     /locus_tag="VQ873_001901"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3108116.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2320..2766
                     /locus_tag="VQ873_001902"
     CDS             2320..2766
                     /locus_tag="VQ873_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3108117.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2763..3878)
                     /locus_tag="VQ873_001903"
     CDS             complement(2763..3878)
                     /locus_tag="VQ873_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3108118.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3992..4216)
                     /locus_tag="VQ873_001904"
     CDS             complement(3992..4216)
                     /locus_tag="VQ873_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3108119.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4161..4532)
                     /locus_tag="VQ873_001905"
     CDS             complement(4161..4532)
                     /locus_tag="VQ873_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3108120.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4591..6024)
                     /gene="glgA"
                     /locus_tag="VQ873_001906"
     CDS             complement(4591..6024)
                     /gene="glgA"
                     /locus_tag="VQ873_001906"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3108121.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6021..7160)
                     /gene="glgD"
                     /locus_tag="VQ873_001907"
     CDS             complement(6021..7160)
                     /gene="glgD"
                     /locus_tag="VQ873_001907"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3108122.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7150..8292)
                     /locus_tag="VQ873_001908"
     CDS             complement(7150..8292)
                     /locus_tag="VQ873_001908"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3108123.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8282..10210)
                     /gene="glgB"
                     /locus_tag="VQ873_001909"
     CDS             complement(8282..10210)
                     /gene="glgB"
                     /locus_tag="VQ873_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3108124.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3195 a         2299 c         1846 g         3151 t
ORIGIN      
        1 agcttggttt cagaaatttc tcttaccaac attaaccgca ccattggtta ttatattaaa
       61 acgaagtaag aataggacaa atcgatcagg acagtaaaat ctaattctaa caatgtttta
      121 gaagtagagg tgtactattc tagtttcaat ctactatatt aatggacaat gcaagattcc
      181 atagaatggg gaagctagaa ctcttgtgtg aagagtttgg gcataaactt ttacctcttc
      241 ctccctactc gcctgagtac aatcttattg agaaaacatg ggctcatatc aaaaagcacc
      301 tcaaaagggt attaccaagt tgcaatacct tttatgaggc tcttttgtct tgttcttgtt
      361 tcaattgact atataaattg tctaagcgaa acaaccgata agaattggca caaaagcgac
      421 cgtatttttg ttaccaatac aggaaaacca gttcatagtt ctatcttgag caagtctctc
      481 cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgtcccc tcacatcttc
      541 agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac aatcacggac
      601 agggttggtc attccgactc tgaagtcact acttccatct acacccacgt cacaaagaac
      661 atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt ttaaaaagtt
      721 ttgtcccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc cgaggggcta
      781 gaaacgttgt taaatcaacg gccgaacttt tgaatttcat ggttcgggat aaaatagttc
      841 actgaactat tttatttttt aaggttgtag aatgatttca atccacgata ttcagctact
      901 tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatgcg gtctgtacgt
      961 gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcaatatc agcgattgtt
     1021 gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc ttctttagcc
     1081 atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt gataaggatt
     1141 gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt tacgaagaag
     1201 tcgtcaccaa caagttgtac tttcttacca agacgttcag taagagcttt ccaaccatcc
     1261 cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttgtt aaccaattct
     1321 tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc ttcaaattta
     1381 gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca gtcaaatccg
     1441 ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag gatagtttca
     1501 acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc tacggcagtt
     1561 tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc accgtaacga
     1621 agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg gaaagcgatt
     1681 ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg aagaacttta
     1741 gtgttgaatc caccaaggta gctgtaaagt gggatttcaa ggtagtcagc agcagcacga
     1801 gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt gttaggagta
     1861 ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc gtagccaatg
     1921 atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc aagaccaccg
     1981 taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt agaagctcct
     2041 gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac ttcaagtgtt
     2101 gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat tgacattttt
     2161 tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc cctccttttt
     2221 caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa tcgctttctt
     2281 ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt atcaaaacaa
     2341 ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgagcaaag acgctatctt
     2401 ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa tagccctcag
     2461 ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaga gccactattt
     2521 gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa agaagcaaaa
     2581 gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc tttgggcctg
     2641 gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact tgcttttcca
     2701 aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa gaaatggttt
     2761 agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg ctccagatag
     2821 agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat agaaaagaca
     2881 gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc gcaaatagca
     2941 ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt cccagcaaag
     3001 ctttgactat caagtcttcc ttctccaaca acaaccaagt cagcatctga aactttctta
     3061 tcaaagttga ttaagtccaa gcaggtatca attccagaca cgatacttgc ctgagcaaag
     3121 gcacacaaac caccagcaag gcctccacct gctcctgctc ctttaatttc taatgttgca
     3181 ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa catagtcgga
     3241 tgtagacctt tttgattgcc aaaagtgtaa gtcgcacctt gatgaccaca taagggactc
     3301 acgacatctg ctagaatatg aatttgaaca ccttcaggaa ttttatagca attttctgtt
     3361 gaaacagaag ctaagtttaa taaggattga tcggaagcag gcaagacatt tccatcccta
     3421 tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt actggccgtg
     3481 ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag aatcaactct
     3541 ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat ttttccaaga
     3601 ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata gcgcatggct
     3661 tctttttgtc cagaagggtc tgtcacttgg atccattttt cttttaggtc aagagaatgt
     3721 cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag acattctaca
     3781 tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg agctgtcaag
     3841 ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat tctaaacagt
     3901 caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt atttcttttt
     3961 tgagcatttc tttggaacaa aaggcgattc ctcactccgc cgacttcaac attaatagat
     4021 tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt ttctttctcc
     4081 atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact aattttcctg
     4141 ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata ccaagggatt
     4201 ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac taggatgcca
     4261 ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat tgagttgaag
     4321 acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt tcttaaactg
     4381 ctttcaaaga ccaactctcc tcgcattgct cgacttgtaa tctgcgaaat ttccgcctca
     4441 tgacctgcct ctctccctaa aagatcaatc acttcttcta ggattaaggt tccatctaca
     4501 tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac agcctaaaaa
     4561 tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt acaagtcaag
     4621 gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt tttgtaggtt
     4681 tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag tccaatttaa
     4741 ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga ttggattgaa
     4801 agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg ttccataacg
     4861 catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga ggaagaggtc
     4921 acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg ttgatagctt
     4981 gtctgggtaa atctgagcaa accatgagaa agctccttca aaggctggat cgccagttcc
     5041 caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga ccaccacatc
     5101 aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt ctgctctaac
     5161 aggcaagcca actctttctt gcaattttgc cttatttttg gctttcccag acaaatcttc
     5221 ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat cagcatcaat
     5281 cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat ccaaattaca
     5341 tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacagttg aaacacggtt
     5401 cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa gggtgccatc
     5461 agcgtaacgt tcaaagccaa ctccaaacaa atcacccaac attccttctg aaaattgtcc
     5521 ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg cttgaatcca
     5581 acggtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat gaacatggag
     5641 aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt ggaaaaaggc
     5701 aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat aatattgatt
     5761 gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac aatactgtct
     5821 gcgccaacca acgctcacct caaaatgaag cacatcttca atctgacttc caaatttagc
     5881 ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt ttaccagtga
     5941 ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaagg gtgcaccctc
     6001 tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc acctttctta
     6061 accacaactg gatgttctgc agttcctcga atcacaacac caggctcaac ttcaacccct
     6121 ttgtccaaga tagcatattc gacctgagcc ccttctccaa taacaacacg agggaagagc
     6181 aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag aacagaatta
     6241 gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac cttagatgta
     6301 ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg gtttggtgag
     6361 aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata ataagattta
     6421 acagagtgaa tattggctag atagcccgtg tactcgtagg cgaaagctcc ctcttttaca
     6481 gccaaatccc gtaaaacata gcgcaatttc tctggatgtt cttttttagc ttcttcttcc
     6541 aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat attgaacgtt
     6601 tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt ttcatctaca
     6661 tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata aactacagtg
     6721 ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat gttaataaga
     6781 acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata agtaagaagc
     6841 tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta aattcctaga
     6901 tagtaatggc taagaagggt tgataagccc cactcgcgtc ctgaacgaat atggtcaaat
     6961 actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc tgcattagca
     7021 aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa acttgctact
     7081 ggacggtggt ccgtcaatgt cgacatattg tgaaaaccaa ctgtatttcc taaaatggca
     7141 gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc ctacaacttg
     7201 tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt caccaataat
     7261 ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa ctgaatcaag
     7321 gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt taacagttcc
     7381 atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg ccccgaggaa
     7441 gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac gactatccaa
     7501 ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa tagtaccaac
     7561 atctttccaa taaccactaa attcataagc ataaacactt tcacctgact caaggtaatt
     7621 tggaatgaca tttttaccaa agtctgacat gccaaccttg ctcttttcag cagcgactaa
     7681 catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt ttgtagattt
     7741 aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg tgttcatgat
     7801 accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca agctggcatt
     7861 attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt ggtccccaga
     7921 caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt ggtaaatagc
     7981 gtgactagtc ccctcaaacc aacgatttcc ttcacttgca gaataaggtt gaagaataga
     8041 gacacctgaa ttaataccgt ctagtcccca gcttgaacca ttcccaatat ggttgttgag
     8101 agcaagtggt tgatactgtg taacgacccc aacattatga atccctgagt tggcacagtt
     8161 tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg gttttgcgat
     8221 gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca aagctaacat
     8281 ttcatttttc attttctact cctttttggt ttttatttgt gacggtttta gtagatttca
     8341 agcgacgttt gattttccat acacttgctc ccatagccgg tagagtaaag gttaaggtct
     8401 gctcataatc tttccatagt ccttcttgcg tttgaacagt ttgattatgt tctttccaaa
     8461 cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct gcaacgggta
     8521 gtccgattgt aaaatctttc cgctcaacag gtaccatatt aaagatacag actaacattt
     8581 ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta tccgcatcaa
     8641 tgatttcaat accatcatag ctggtatcaa tttcccacag acagcgatga tctttgtaaa
     8701 actggtttag ctgagaagcg aaatacttca tcttagcatt cattgggtct tctaggttag
     8761 accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg ctacccatga
     8821 agagcaattt cttaccaggg tgacaaattt ggtacgtata gagattgcgc aagcctgcga
     8881 attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca tgaaccactt
     8941 catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag ctgaaagtca
     9001 ccaggttaaa gtcatattta cgataaatcg gatcttcttc gtagaaacgg aggatatcat
     9061 tcatccagcc catgttccat ttgtagtcaa atcctagact accaatctct ttcattcccg
     9121 taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatctgga tattctaact
     9181 taataacttc attcaagcgt tgaagaaaat aataaccttc atagttgaga tttccgccat
     9241 ctttattagg tgtccatgga gcattatcat agtccaaata gagcatgttg ctaacagcat
     9301 ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa gaaattaaga
     9361 aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca tggttatgag
     9421 ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct aaggcatcat
     9481 cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta tgggtatgac
     9541 actcctcgac aaaatcttga aactcctctg gtctgccata agcatgctct aaagcgaagt
     9601 aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag ggcataaact
     9661 caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg agctgggcaa
     9721 aactataagg actgccatca gaatttcttt tccatgatcc agcgtgaact tcataaatat
     9781 tgacaggacg ctcttcaaag ccccaacgtt ttcttcgtgc cagccaaagt ccatccttcc
     9841 atttcttctc aggaagctct gttaagattg cccctgttcc tggacgagcc tcatacctga
     9901 cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca tgatatttgt
     9961 aaatatgccc ttcttgagcc atattggtaa agacttccca gaccccaaaa tcatttctta
    10021 ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga acagcctgag
    10081 cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct tccctatgtg
    10141 ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt aatgcttctc
    10201 tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt atactacctt
    10261 tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa tctacaacaa
    10321 gttcacttac tcgttcaatt gtaaatcaat attttttcaa aaaattgcga aaacgccttt
    10381 ctttttctac tatagtgaaa tgaaataaaa catgcgcaag tcgattaagg aatttaatct
    10441 aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg t
//
LOCUS       DAVBOH010000066         9777 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBOH010000066 DAVBOH010000000
VERSION     DAVBOH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.066"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ873_001910"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ873_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ873_001911"
     CDS             complement(546..1166)
                     /locus_tag="VQ873_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3108125.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ873_001912"
     CDS             complement(1166..1648)
                     /locus_tag="VQ873_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3108126.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ873_001913"
     CDS             complement(1648..2490)
                     /locus_tag="VQ873_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3108127.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ873_001914"
     CDS             complement(2585..3385)
                     /locus_tag="VQ873_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3108128.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ873_001915"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ873_001915"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3108129.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ873_001916"
     CDS             4918..5463
                     /locus_tag="VQ873_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3108130.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ873_001917"
     CDS             5475..5789
                     /locus_tag="VQ873_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3108131.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ873_001918"
     CDS             5806..6498
                     /locus_tag="VQ873_001918"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3108132.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ873_001919"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ873_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3108133.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ873_001920"
     CDS             7140..7730
                     /locus_tag="VQ873_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3108134.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ873_001921"
     CDS             7739..9502
                     /locus_tag="VQ873_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3108135.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3027 a         1695 c         2080 g         2975 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
     9721 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtat
//
LOCUS       DAVBOH010000067         9740 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBOH010000067 DAVBOH010000000
VERSION     DAVBOH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.067"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ873_001922"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ873_001922"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3108136.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ873_001923"
     CDS             1085..2809
                     /locus_tag="VQ873_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108137.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ873_001924"
     CDS             2811..4559
                     /locus_tag="VQ873_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108138.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ873_001925"
     CDS             4816..6075
                     /locus_tag="VQ873_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3108139.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ873_001926"
     CDS             6325..6825
                     /locus_tag="VQ873_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3108140.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ873_001927"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ873_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3108141.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ873_001928"
     CDS             7456..7629
                     /locus_tag="VQ873_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108142.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ873_001929"
     CDS             7626..8222
                     /locus_tag="VQ873_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3108143.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ873_001930"
     CDS             8259..8396
                     /locus_tag="VQ873_001930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108144.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9740
                     /gene="dcm"
                     /locus_tag="VQ873_001931"
                     /pseudo
     CDS             8495..9740
                     /gene="dcm"
                     /locus_tag="VQ873_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
BASE COUNT         2900 a         1839 c         2179 g         2822 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg tcgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca
//
LOCUS       DAVBOH010000068         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOH010000068 DAVBOH010000000
VERSION     DAVBOH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.068"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ873_001932"
     CDS             complement(358..1965)
                     /locus_tag="VQ873_001932"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3108145.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ873_001933"
     CDS             complement(2355..2942)
                     /locus_tag="VQ873_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3108146.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ873_001934"
     CDS             complement(3070..3519)
                     /locus_tag="VQ873_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108147.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ873_001935"
     CDS             complement(3524..3913)
                     /locus_tag="VQ873_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3108148.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ873_001936"
     CDS             complement(3941..4567)
                     /locus_tag="VQ873_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3108149.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ873_001937"
     CDS             complement(4581..5144)
                     /locus_tag="VQ873_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3108150.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ873_001938"
     CDS             complement(5597..6100)
                     /locus_tag="VQ873_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3108151.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ873_001939"
     CDS             complement(6293..7123)
                     /locus_tag="VQ873_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3108152.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ873_001940"
     CDS             complement(7108..8790)
                     /locus_tag="VQ873_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108153.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOH010000069         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBOH010000069 DAVBOH010000000
VERSION     DAVBOH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.069"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ873_001941"
     CDS             complement(549..857)
                     /locus_tag="VQ873_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3108154.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ873_001942"
     CDS             complement(854..1162)
                     /locus_tag="VQ873_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3108155.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ873_001943"
     CDS             complement(1167..2462)
                     /locus_tag="VQ873_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3108156.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ873_001944"
     CDS             complement(2480..3889)
                     /locus_tag="VQ873_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3108157.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ873_001945"
     CDS             4047..4775
                     /locus_tag="VQ873_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3108158.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ873_001946"
     CDS             5234..5428
                     /locus_tag="VQ873_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3108159.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ873_001947"
     CDS             complement(5793..7103)
                     /locus_tag="VQ873_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3108160.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ873_001948"
     CDS             7340..8212
                     /locus_tag="VQ873_001948"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3108161.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBOH010000070         8266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOH010000070 DAVBOH010000000
VERSION     DAVBOH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.070"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ873_001949"
     CDS             226..6657
                     /locus_tag="VQ873_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3108162.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ873_001950"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ873_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7394..7579)
                     /locus_tag="VQ873_001951"
                     /pseudo
     CDS             complement(7394..7579)
                     /locus_tag="VQ873_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7607..7834
                     /locus_tag="VQ873_001952"
     CDS             7607..7834
                     /locus_tag="VQ873_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3108163.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7910..8266
                     /locus_tag="VQ873_001953"
                     /pseudo
     CDS             7910..8266
                     /locus_tag="VQ873_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3140 a         1164 c         1625 g         2337 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact ataaatccac gtttacgaat ctctttccac acttgttcaa
     7441 tggggttcat ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct
     7501 ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga taatcatctg
     7561 gataagcttg tgaaagctcc tattcctaaa gcccctttat aacctcttgc gagagagact
     7621 attgactcag cccttacttc atgcggatga aacttcttat cgggttctag agagtcatag
     7681 ccatctgacc tactattgga cctttttgtc tgggaaagtt gagaatcaag caatcacgct
     7741 gtaccatcat gatcagagtc ggagtggttc ggtagtacaa gaattcctag gagattattc
     7801 tggctatgtt cattgtgata tgttgcggca gtaacttagg actttagtcc tctagttctg
     7861 cctatgcgat agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaactgcga
     7921 accgctagaa gcttatcgtc aactggcaga agctgaactt gttggatgtt gggcgcatgt
     7981 gagaaggaaa ttttttgaag cgacccccaa gcaagcagat aaatcatcct taggagctaa
     8041 aggtttagct tattgtgatc agttattttc cttggaaaga gactgggagg ctttgccagc
     8101 tgatgaacga ctacagaaac gtcaagaaca tctccagccc ctaatggaag acttctttgc
     8161 ttggtgccgc cgtcagtcag ttttagcagg ttcaaaacta ggaagggcaa ttgaatacag
     8221 cctcaagtat aaagaaacct ttaagactat tttgaaagac ggacat
//
LOCUS       DAVBOH010000071         7482 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOH010000071 DAVBOH010000000
VERSION     DAVBOH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.072"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            155..310
                     /locus_tag="VQ873_001954"
                     /pseudo
     CDS             155..310
                     /locus_tag="VQ873_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            510..3785
                     /gene="rexB"
                     /locus_tag="VQ873_001955"
     CDS             510..3785
                     /gene="rexB"
                     /locus_tag="VQ873_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3108164.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3782..7432
                     /gene="addA"
                     /locus_tag="VQ873_001956"
     CDS             3782..7432
                     /gene="addA"
                     /locus_tag="VQ873_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3108165.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKNQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2278 a         1572 c         1593 g         2039 t
ORIGIN      
        1 attgtgtact atttttggtt cattttacta tagtagattg aaataagata cgaacagctt
       61 gattagggaa atcaaattaa tttctagaaa tattttagca tccacggtgt actattatag
      121 tttcaattta ctatagttca atcattctat caagaatatt gaatatataa aggcacgtaa
      181 tattaaaact tcttctgata tcgaattaga gtccgatgtt gatggcgata aatcagacaa
      241 tctaccagtc gacattaaga tactgggaca acacattgaa gtgtattccg tacctaagaa
      301 acaatcataa aactcaaagc cttgttaccg aggctttttt attatgtgat tttcagtagc
      361 cagacttatt ctatctaata caagtaaagc taagtattta agatttagca gatgatgaag
      421 aaaagaaagg atggcctaaa tattttaaca gatttacgag gctaatcatg gtataatata
      481 gggtgatgaa aaattccaac gaggctgaga tgaaattact ttatactgat attcggactt
      541 ctttgacaga aattctaaca agagaggcag aagagctagt tgcagctggc aagcgggtct
      601 tctacattgc ccccaactct ctttcttttg aaaaggaacg cgccgtgctg gaatgcttgt
      661 cccagcaggc ttctttttcg attaccgtca cgcgctttgc tcaaatggct cgttatctgg
      721 tcttgaatga tttaccagct aaaactactc ttgatgatat cggtcttggg ttggcctttt
      781 acaaatgcct tgccgaactc gatcccaagg acttgcgtgt ttatggcgct attaagcagg
      841 atcctcaatt gatccagcag ttaattgagc tttaccatga gatgaccaaa tcccagatga
      901 gttttttgga cttggagaat ttaacagatg aggataagag ggcggattta ctcttgattt
      961 ttgagaaagt aacagcctat cttaatcaag gtcagttagc ccagggaagt cagttgtccc
     1021 atttgattga ggctattgag aatgacaagg taagtagtga ttttaatcaa atcaccttgg
     1081 tcattgacgg ctttactcgt ttttctgctg aggaagagcg ggttgtggac ttacttcacg
     1141 gcaaaggtgt tgagattgtt atcggggctt atgctagtaa gaaagcctat accagtcctt
     1201 ttagcgaggg caatctctac caagccagcg taaaatttct ccatcatctg gcttctaaat
     1261 accaaacgcc tgctcaggac tgttctcaaa ctcatgagaa gatggatagt tttgacaagg
     1321 cctctcgttt gttggagtct tcttatgact tttcagaact cgctttggat gtcgatgaga
     1381 aagaccgtga aaatttacaa atctggtctt gtttgacgca aaaggaggag ttggagctag
     1441 tagcccgtag tattcgtcag aaattacatg agaactcaga cctgagctac aagcattttc
     1501 gtattctctt gggggatgta gcttcttacc agttatctct caaaaccatt tttgaccagt
     1561 atcagattcc tttttatctt ggtagaagcg aagccatggc tcatcatccc ttgactcagt
     1621 ttgtcgagtc tattttagct ttaaaacgtt accgttttcg tcaggaggat ttgattaatc
     1681 ttcttagaac tgatttgtat actgacctca gtcagtctga tattgatgct tttgagcaat
     1741 atatccgcta tcttggtatc aatggcttgc cagcctttca gcaaatcttc accaaatccc
     1801 accatggaaa atttaatctt gagcgtttga atgtcctccg cctgagaatt ttagcacctc
     1861 ttgaaaccct ctttgccagc cgaaaacaaa aggctgaaaa cctcctacaa aaatggagtg
     1921 tctttctaaa agaaggagct gtgaccaagc agttacaaga tttgacaacc actttggaag
     1981 ctgtagaaca ggaaagacaa gccgaagttt ggaaggcttt ctgccatgtt ttagaacaat
     2041 ttgcgactgt ttttgctggt tcacaggtta gtctggaaga cttcctagcc ttgctccatt
     2101 ctggaatgag tttgtcccaa taccgtacca ttccagcaac agtggacact gttctggtgc
     2161 agagttacga tttgattgca ccattgactg ctgactttgt ctatgctatt ggactaactc
     2221 aggacaattt accaaaaatt tctcaaaaca ccagtcttct gacagatgaa gaaaggcaaa
     2281 acctaaacca agcgaccgaa gaaggcgttc aattactgat tgccagcagt gaaaatctca
     2341 agaaaaatcg ctacactatg ctttccttgg tcaattctgc tcgtaagcag ttgttcttgt
     2401 cggctccaag cctttttaac gaaagtgaaa gtaaggaatc tgcctatctt caagagttga
     2461 tccattttgg atttaggcgg agagagaaga ggatgaatca caaaggactg tctaaggagg
     2521 atatggggtc ctatcacagt cttttgtcta gtctggttgc ctatcaccag cagggtgaga
     2581 tgagcgatac tgagcaagat ttgacttttg tcaaggttct gtcgcgtgtc ataggtaaaa
     2641 aactagatct gcaaggtctg gaaaatccag ctatcccaac cagtccaagc agcaagacct
     2701 tagccaagga caccttgcaa gctctctatc ctgccaaaca ggagttttac ctgtctacgt
     2761 cgggtttgac agagttttat cgcaatgaat acagttattt cctacgctac gttttaggct
     2821 tgcaggagga attacgtttg cgtcctgatg cccgtagtca cgggaatttc ttgcatcgta
     2881 tctttgaacg cgccttacag ttgcctaatg aagattcctt tgaccaacgt ctagaacaag
     2941 ctattcaaga aaccagtcaa gaacgcgaat ttgaagctat ttatcaagaa agtttggaag
     3001 cccagtttac caaggaagtt ttgcttgatg ttgcacggac gactggacat attctccgac
     3061 acaatccagc catcgaaacc atcaaagaag aagcaaattt tggtggaaaa gaccaagcct
     3121 ttattcaatt agacaatgga cgcagtgtct ttgtacgagg caaggtggac cggattgacc
     3181 gtttgaaagc taatggagcg ataggagtag tagactacaa atccagtctg actcagttcc
     3241 agtttcctca tttctttaat gggctcaatt ctcagttacc aacctatctt gctgccctaa
     3301 aaagagaagg gaagcagaac tttttcggcg ccatgtactt ggaaatggct gaacctgtcc
     3361 aatctctgat ggcggtaaaa agtctggcag gagcagtggt agaagccagc aaatctatga
     3421 aataccaagg gctcttcttg gaaaaagaaa gcagttattt aggcgaattt tataacaaaa
     3481 acaaggctaa tcaactgaca gatgaggaat ttcagctcct actggactac aatgcctatc
     3541 tttacaagaa agctgctgag aagattttag caggccggtt cgccatcaat ccttatactg
     3601 aaaatggcag aagcattgcc ccatacgtcc agcaacatca ggctattaca ggctttgaag
     3661 ccaattacca tctgggccaa gcccgtttcc tagaaaaatt ggacctagct gatggcaagc
     3721 gtctggtcgg agaaaaactc aagcaagctt ggtttgaaaa aataagagag gagttaaatc
     3781 gatgaagctt attccctttt taagtgagga ggagattcaa aaactgcaag aagcagaagc
     3841 aaattcgagc aaggaacaga agaaaactgc cgaacaaatc gaagctatct acacttctgg
     3901 tcagaatatc ctggtctcag catcggctgg ttctggaaag acctttgtca tggcagagcg
     3961 cattctggac caattggcgc gtggtgtcga aatttctcaa ctctttatct caacctttac
     4021 cgtcaaggct gcaactgaac ttaaagaacg tttagagaaa aaaatcagca agaaaatcca
     4081 agaaacagat gatgtcgatc tcaaacaaca cttgggacgc cagttggcag acctacccaa
     4141 cgctgccatc ggaaccatgg actctttcac acaaaaattc cttggcaaac atggttatct
     4201 gcttgatatt gcacctaatt tccgtatttt acaaaaccaa agcgagcaac ttcttctcga
     4261 aaacgaagtc tttcatgagg tctttgaagc gcattaccaa ggtaaacaga aagagagctt
     4321 tagtcatttg ctgaaaaact ttgctgggcg tggcaaggac gaacggggtc tgcggcagca
     4381 agtctataaa atctatgact tcctccaatc caccagtaat cctcaaaagt ggctgagtga
     4441 atctttcctc aaaggctttg agaaagctga ttttaccagt gaaaaagaaa aactgactga
     4501 gcaaatcaaa caagccctct gggatttgga aagatttttc cgttaccatc tggataacga
     4561 tgccaaggag tttgcaaagg ctgcctattt agaaaatgtt cagttaattc tggatgaaat
     4621 tggctcccta aatcaggagt tcgatagtca ggcttatcag gcagtacttg cgcgtgttgt
     4681 cgccatctct aaggagaaaa acggtcgtgc tctgactaat gccagccgta aggctgattt
     4741 gaagcccctg gctgatgcct acaacgaaga gagaaagaac cagtttacta aactaggaca
     4801 attatcagac cagatagcga ttctcgacta tcaagaacgt tatcatggag acacttggaa
     4861 actagctaaa accttccaat ctttcatgag cgattttgta gaggcttatc gtcagagaaa
     4921 acgacaggaa aatgcctttg aattcgctga tatcagccat tacaccattg agattttaga
     4981 aaatttccca caagttcgtg agtcttatca ggagcgcttc catgaagtca tggtcgatga
     5041 gtatcaggat accaaccata ttcaagaacg gatgctggaa ttgttgtcta atggccacaa
     5101 tcgctttatg gtgggagata tcaagcaatc catctatcgt ttccgtcagg cagacccgca
     5161 gattttcaat gagaaattcc aacgctatgc gcaaaatccc caagaaggca agctcattct
     5221 cctcaaggaa aatttccgta gtagttcaga agtgctgtca gcaaccaatg atgtctttga
     5281 acgtctcatg gaccaagagg tcggcgaaat caactatgat aacaagcacc agcttgtttt
     5341 tgccaatacc aaactgactc ccaatccaga caacaaggca gaatttctcc tctacgacaa
     5401 ggacgataca ggtgaggaag aagagagtca aacagaaacg aaactaacag gcgaaatgcg
     5461 cttagttatc aaggagattc tgaaacttca tcaagaaaaa ggtgttgcct ttaaggaaat
     5521 tgcccttctg acctccagcc gcagtcgtaa tgaccagatt ctcctcgccc tgtctgagta
     5581 cgggattcct gtcaaaactg acggagagca aaacaattat ctccaatccc tagaagtgca
     5641 agtcatgcta gacactcttc gtgtcattca caatcccctg caagactatg ccttggttgc
     5701 ccttatgaag tctccaatgt ttggttttga tgaggatgag ctagcacgtt tgtcccttca
     5761 gaaagcagag gataaagtcc acgaaaatct ctatgagaaa ctggtcaatg cacaaaaaat
     5821 ggcaagtagt caaaaaggct tgattcacac agctctagct gaaaaactaa agcaattcat
     5881 ggatatccta gcttcttggc gcttgtatgc caaaacccac tctctctatg acttgatttg
     5941 gaagatttac aacgaccgtt tttattatga ctatgttggg gctttgccga atggtcctgc
     6001 taggcaggcc aatctctatg ccctagcact gcgtgctgat caatttgaaa agagcaattt
     6061 caaaggtttg tcgcgtttta ttcgtatgat tgaccaagtc ttagaagccc agcacgattt
     6121 gtcaagcgtg gccgtcgcac cgccaaaaga tgcagtagag ctcatgacca tccacaagag
     6181 taaagggctg gagtttcctt acgtctttat cctcaatatg gatcaagatt tcaacaagca
     6241 agactctatg tcagaagtca ttctcagtcg tcagaatggt cttggtgtca aatatattgc
     6301 caagatggag acaggggcag tagaagacca ctatcctaaa accatcaaac tctccattcc
     6361 tagtctgacc tataggcaga acgaagagga attacagcta gcaagctatt ctgagcagat
     6421 gcgtttgctg tatgttgcta tgacgcgggc tgagaaaaag ctctatcttg tcggcaaggg
     6481 ttctcgtgaa aagctggaag tcaagcaata cccagcagcc aaaaatggga aactaaatag
     6541 caatactaga ctgcaagcac ggaatttcca agattggctt tgggctatca gtaaagtgtt
     6601 tactaaggac aagctcaact ttagttatcg ttttattggc gaagatcagt tgaccagaga
     6661 agctatcgga gagttggaaa ccaagagtcc tctccaagat agctcccaag cagacaatcg
     6721 tcagtcagat accatcaaag aagctctgga aatgctgaag gaggtggaag tttataatac
     6781 tcttcaccgc gcagctattg aacttcctag tgttcaaacc ccaagtcaaa tcaagaaatt
     6841 ctacgaacca gttatggata tggaaggtgt cgagattgct ggtcaaggtc agtcagtagg
     6901 caagaaaatc agcttcgatt tgccagattt ttcaaccaaa gaaaaggtaa ctggagctga
     6961 gattggtagt gctactcacg aactcatgca gagaattgac ctcagccagc aactaaccct
     7021 tgctagccta acagaaacac tcaaacaagt tcaaactagc caagctgtca gagacaagat
     7081 caatcttgat aaaattcttg ctttctttga cacagtactc ggtcaggaaa ttcttgctaa
     7141 taccgaccat ctctatcgcg agcaaccttt ctccatgctc aaacgagacc aaaagagtca
     7201 ggaagacttt gttgtccgtg gtatccttga tggctatctg ctttacgaaa acaaaattgt
     7261 tctgttcgac tacaagacag accgctatga tgaaccaagt caactcgtag accgctatcg
     7321 tggtcagtta gctctatacg aagaggcttt atcacgagcc tattcgattg aaaatattga
     7381 aaaatacttg attttactcg gtaaagacga ggttcaagtt gtaaaagtat aacttatact
     7441 ctttgaaaat ctcttcaaac cacgtcagct tcgccttgct gt
//
LOCUS       DAVBOH010000072         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBOH010000072 DAVBOH010000000
VERSION     DAVBOH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.073"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ873_001957"
     CDS             52..693
                     /locus_tag="VQ873_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3108166.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ873_001958"
     CDS             complement(735..2723)
                     /locus_tag="VQ873_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108167.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ873_001959"
     CDS             complement(2725..3483)
                     /locus_tag="VQ873_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108168.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ873_001960"
     CDS             3911..4102
                     /locus_tag="VQ873_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108169.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ873_001961"
     CDS             complement(4456..4728)
                     /locus_tag="VQ873_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3108170.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ873_001962"
     CDS             complement(4787..5236)
                     /locus_tag="VQ873_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3108171.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ873_001963"
     CDS             complement(5223..7352)
                     /locus_tag="VQ873_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3108172.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBOH010000073         7451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOH010000073 DAVBOH010000000
VERSION     DAVBOH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.074"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ873_001964"
     CDS             complement(173..1588)
                     /locus_tag="VQ873_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3108173.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ873_001965"
     CDS             complement(1601..3439)
                     /locus_tag="VQ873_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3108174.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ873_001966"
     CDS             complement(3457..4296)
                     /locus_tag="VQ873_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3108175.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ873_001967"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ873_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2443 a         1568 c         1026 g         2414 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacgaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca t
//
LOCUS       DAVBOH010000074         7292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOH010000074 DAVBOH010000000
VERSION     DAVBOH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.075"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ873_001968"
     CDS             complement(112..387)
                     /locus_tag="VQ873_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3108176.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ873_001969"
     CDS             complement(494..1333)
                     /locus_tag="VQ873_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3108177.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ873_001970"
     CDS             1475..2323
                     /locus_tag="VQ873_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3108178.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ873_001971"
     CDS             complement(2416..3333)
                     /locus_tag="VQ873_001971"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3108179.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ873_001972"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ873_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ873_001973"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ873_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3108180.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ873_001974"
     CDS             complement(4596..4940)
                     /locus_tag="VQ873_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3108181.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ873_001975"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ873_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3108182.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ873_001976"
     CDS             complement(5488..6087)
                     /locus_tag="VQ873_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3108183.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ873_001977"
     CDS             6557..6856
                     /locus_tag="VQ873_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3108184.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..>7292
                     /locus_tag="VQ873_001978"
     CDS             7075..>7292
                     /locus_tag="VQ873_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3108185.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         2335 a         1474 c         1193 g         2290 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga at
//
LOCUS       DAVBOH010000075         6938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOH010000075 DAVBOH010000000
VERSION     DAVBOH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.076"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ873_001979"
     CDS             complement(57..287)
                     /locus_tag="VQ873_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108186.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ873_001980"
     CDS             complement(305..946)
                     /locus_tag="VQ873_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3108187.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ873_001981"
     CDS             complement(958..1692)
                     /locus_tag="VQ873_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3108188.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ873_001982"
     CDS             complement(1695..1892)
                     /locus_tag="VQ873_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108189.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ873_001983"
     CDS             complement(1892..2098)
                     /locus_tag="VQ873_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3108190.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ873_001984"
     CDS             complement(2108..2422)
                     /locus_tag="VQ873_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108191.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ873_001985"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ873_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ873_001986"
     CDS             complement(2718..4007)
                     /locus_tag="VQ873_001986"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3108192.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ873_001987"
     CDS             complement(4104..5333)
                     /locus_tag="VQ873_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3108193.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ873_001988"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ873_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3108194.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ873_001989"
     CDS             6501..6842
                     /locus_tag="VQ873_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3108195.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTLTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2250 a         1440 c         1275 g         1973 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccaccg aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggacagct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt aaccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagcc
//
LOCUS       DAVBOH010000076         6843 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOH010000076 DAVBOH010000000
VERSION     DAVBOH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.077"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ873_001990"
     CDS             complement(58..384)
                     /locus_tag="VQ873_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3108196.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ873_001991"
     CDS             complement(351..635)
                     /locus_tag="VQ873_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3108197.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ873_001992"
     CDS             complement(908..1750)
                     /locus_tag="VQ873_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3108198.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ873_001993"
     CDS             complement(1864..3255)
                     /locus_tag="VQ873_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3108199.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ873_001994"
     CDS             complement(3490..3867)
                     /locus_tag="VQ873_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3108200.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ873_001995"
     CDS             4082..5059
                     /locus_tag="VQ873_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3108201.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ873_001996"
     CDS             5056..6138
                     /locus_tag="VQ873_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3108202.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6202..6843)
                     /locus_tag="VQ873_001997"
                     /pseudo
     CDS             complement(6202..6843)
                     /locus_tag="VQ873_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2058 a         1496 c         1159 g         2130 t
ORIGIN      
        1 tctaccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tataaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
     6301 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
     6361 cacttgttca atgggttcat ctctggtgtg tatggaggaa taaaggtaaa atcaatatta
     6421 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaaa
     6481 taatcatctg gataagcttg tgaaagctct tctaaaaagg cgttcatcca ctcagtatta
     6541 catccaccag ctattaagaa aaatgattcg cctgtatggg catcaacagc tccataacaa
     6601 tagcgaaatt ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa
     6661 caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat caagcgaacc
     6721 ttatgaaaag gtctactggt tttaaagcgc tttcttgtct tcttgaattg agattttatt
     6781 tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcgtaat
     6841 att
//
LOCUS       DAVBOH010000077         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOH010000077 DAVBOH010000000
VERSION     DAVBOH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.078"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ873_001998"
     CDS             138..860
                     /locus_tag="VQ873_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3108203.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ873_001999"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ873_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3108204.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ873_002000"
     CDS             complement(2467..3378)
                     /locus_tag="VQ873_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3108205.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ873_002001"
     CDS             complement(3402..4205)
                     /locus_tag="VQ873_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3108206.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ873_002002"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ873_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3108207.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ873_002003"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ873_002003"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3108208.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOH010000078         6710 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOH010000078 DAVBOH010000000
VERSION     DAVBOH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6710
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.079"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..282
                     /locus_tag="VQ873_002004"
     CDS             <1..282
                     /locus_tag="VQ873_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3108209.1"
                     /translation="MTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGKLELLCEEF
                     GHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            343..1305
                     /locus_tag="VQ873_002005"
     CDS             343..1305
                     /locus_tag="VQ873_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3108210.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1483..2490
                     /gene="gap"
                     /locus_tag="VQ873_002006"
     CDS             1483..2490
                     /gene="gap"
                     /locus_tag="VQ873_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3108211.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2557..3393)
                     /locus_tag="VQ873_002007"
     CDS             complement(2557..3393)
                     /locus_tag="VQ873_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3108212.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3519..5714
                     /locus_tag="VQ873_002008"
     CDS             3519..5714
                     /locus_tag="VQ873_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3108213.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEELVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5767..5919
                     /gene="rpmG"
                     /locus_tag="VQ873_002009"
     CDS             5767..5919
                     /gene="rpmG"
                     /locus_tag="VQ873_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3108214.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5929..6105
                     /gene="secE"
                     /locus_tag="VQ873_002010"
     CDS             5929..6105
                     /gene="secE"
                     /locus_tag="VQ873_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3108215.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6160..6696
                     /gene="nusG"
                     /locus_tag="VQ873_002011"
     CDS             6160..6696
                     /gene="nusG"
                     /locus_tag="VQ873_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3108216.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2083 a         1180 c         1445 g         2002 t
ORIGIN      
        1 atgacgagcg acttttttga agcttggttt cagaattttc tcttaccaac attaaccaca
       61 ccatcggtta ttattatgga taatgtaaga ttccatagaa tggggaagct agaactttta
      121 tgcgaagagt ttgggcataa actgttacct cttcctccct actcacctga gtacaatcct
      181 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
      241 accttttacg aggctttttt atcctgctct tgtttcaatt gactatatat cacggataca
      301 gttgggaaag aagctattaa atatttggag agtccttttg ggatgaacat gtcaaatatt
      361 actatagatg ggcaagaaat agatctgagt caaacgatgc cttcttatgc tcaagtagtg
      421 agtctttatg atgatacaag tatctctgtt agtagtaatg agacggacaa agtgttggct
      481 ggatccctct atactgatac aaatgaacag ggattaacga ttccaagcag tttactaaaa
      541 aattggaatg aacagacagg aaaaaatttg acagctaatg atcttattgg caaatcagtc
      601 tcagccagca ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag
      661 attgtacgtg taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct
      721 catcaaatgg aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc
      781 ttggaactca aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag
      841 aagtatactg tgctttctca acagagagtt cttgatattg tgattacctt tattcgtgtt
      901 attcagggat tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt
      961 ggtatcatta tttacatcaa tatcatgcaa cgttctaagg aaataggtgt catgaaggca
     1021 gttggttatc agaatcgtga tgtcaaagga atttttattt acgaggctat ctggattgta
     1081 ggcatcgcct tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg
     1141 attgtaagtc acttttaccc atccatcact aaggtttttg aattaaatct tttatctgtt
     1201 ttaggaactc tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt
     1261 aagattagta aaatggatcc tgtagaaccg ttacgctatg aatagtaagg gattccttga
     1321 tttacagtct taaaaaagaa actaacatag aaaaacaatg gccatacttg caattcaact
     1381 caaatagttg tataataggt ttgttgaaag gtgatttgta gtgattcaag ttactctttt
     1441 cacaataaaa atttcatgat tttcataagg aggaaatcac taatggtagt taaagttggt
     1501 attaacggtt tcggacgtat cggtcgtctt gctttccgtc gtatccaaaa cgtagaaggt
     1561 gttgaagtta cacgcatcaa cgaccttaca gatccagtta tgcttgcaca cttgttgaaa
     1621 tacgacacaa ctcaaggtcg tttcgacggt actgttgaag ttaaagaagg tggatttgaa
     1681 gttaacggta aattcgttaa agtttctgct gaacgtgatc cagagcaaat cgactgggct
     1741 actgacggtg tagaaatcgt tcttgaagct actggtttct ttgctaagaa agaagcagct
     1801 gaaaaacacc ttaaaggtgg agctaaaaaa gttgttatca ctgctcctgg tggaaacgac
     1861 gttaaaacag ttgtattcaa cactaaccac gacgttcttg acggtactga aacagttatc
     1921 tcaggtgctt catgtactac aaactgcttg gctccaatgg ctaaagctct tcaagataac
     1981 tttggtgttg ttgaaggatt gatgactact atccacgctt acactggtga ccaaatgatc
     2041 cttgacggac cacaccgtgg tggtgacctt cgccgtgctc gcgctggtgc tgcaaacatc
     2101 gttcctaact caactggtgc tgctaaagct atcggtcttg taatcccaga attgaacggt
     2161 aaacttgacg gatctgcaca acgcgttcca actccaactg gatcagttac tgaattggta
     2221 gcagttcttg aaaagaacgt tactgttgat gaagtgaacg cagctatgaa agcagcttca
     2281 aacgaatcat acggttacac agaagatcca atcgtatctt cagatatcgt aggtatgtct
     2341 tacggttcat tgtttgacgc aactcaaact aaagttcttg acgttgacgg taaacaattg
     2401 gttaaagttg tatcatggta cgacaacgaa atgtcataca ctgcacaact tgttcgtact
     2461 cttgaatact tcgcaaaaat tgctaaataa ttcttgagtt gatagaaagc aaggctttgt
     2521 ggtcttgctt tttatataga aaaatggatg acacgatcat ccattctttt ttaattcttt
     2581 ttcaaatgta tttgaaaggg tagtgaaagt tagcctctct aaagtaagtg ggtgggtaaa
     2641 ggaaagtcgg aaggcatgaa gcataagccg gcttgtcttt gatttactat tatagagagg
     2701 gtctcccagg ataggaagat tatgatgcaa aaggtgcaca cgaatctgat gggttcgccc
     2761 tgtctttagc ttgcaatgag ccaaggaagt cttgtttgag aattgcttta atctgcttac
     2821 atgcgtttca gcatattgcc cattttttgc atcaactatt ctttttctac gatcatggcg
     2881 atcacgtcca attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag
     2941 agcccaatat tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat
     3001 aaaaggattt ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac
     3061 atagcaggtt tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg
     3121 attaccatgc gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata
     3181 aacttcctgc actaagtctg ggttgcccca agggatcgtc ttttggggat aatcttcctc
     3241 gtcaaaagtc aactggcaaa catctccagg atttacgatt tcgttccagt ggacttcttc
     3301 ttgatttatc aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag
     3361 gagttgttcc tcaagtaatt gctttaccgt catttgaggt atagaggcgg gtaatgtaaa
     3421 tgtgaattgc atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa
     3481 ttcttgtctt cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg
     3541 agaaatttct ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta
     3601 tcttacgtcg ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat
     3661 tctggcgtcg ttatcatcta acaaagatta tccttatact aggtttgagt gcaggcttgc
     3721 tagttggaat ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg
     3781 ccttgaaaac tcggactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg
     3841 gtcaaaaggg aacctatgtt gatctgactg atatcagtaa aaacttgcag aatgctgtta
     3901 ttgcgacaga agaccgttct ttctataaaa atgacgggat taactatggc cgtttcttct
     3961 tggctattgt cactgctgga cgttcaggtg gtggctctac cattacccaa cagctggcta
     4021 aaaacgccta tttatcacag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg
     4081 ccttagaatt aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg
     4141 cttattttgg aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt
     4201 ctgcatcaga agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg
     4261 aactgtataa tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttgc
     4321 agaatatggt tgcagcagga tatattgata aaaaccaaga aaccgaagct gctgaagttg
     4381 atatgacttc gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct
     4441 cttattttga tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagagc
     4501 ttgtcaataa tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc
     4561 agattgttta tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat
     4621 caggaagtgt agctctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg
     4681 ctgacaatga taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc
     4741 ctggttctac aattaagcct ttagttgttt atacgccagc agttgaagca ggctgggctt
     4801 tgaataagca gttggataac cataccatgc agtatgacag ctataaggtt gataactatg
     4861 cagggatcaa aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc
     4921 tacctgctgt tgccactgtt aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa
     4981 aattcggact caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg
     5041 ttgaaaccaa ccctcttcaa atggctcaag catacgctgc ctttgcaaat gaaggtttaa
     5101 tgcctgaagc tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgaatc
     5161 ataaaaattc acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga
     5221 tgttggggac tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatgtcatgg
     5281 cagggaaaac tggaacaact gaagcagttt tcaatccgga gtacacaagt gaccagtggg
     5341 taattggtta tactccggat gtagtgatta gccactggct tggctttccg accactgatg
     5401 aaaatcacta tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg
     5461 ccaataccat tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc
     5521 aaaatggaat tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga
     5581 cagatgataa tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc
     5641 gggctatctc agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca
     5701 atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga
     5761 ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat
     5821 tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag
     5881 cattgtggca agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt
     5941 ggagatattt ttagacttct taaagacaca acatggccaa ctcgcaagga aagctggaga
     6001 gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta catttttgac
     6061 cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt
     6121 aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaagga
     6181 tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa
     6241 cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca
     6301 gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat
     6361 gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat
     6421 gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa
     6481 gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt
     6541 gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt
     6601 acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt
     6661 gcagaagtaa acctaaacca aatcgcagaa ttataatcct gagagaggct
//
LOCUS       DAVBOH010000079         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOH010000079 DAVBOH010000000
VERSION     DAVBOH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.080"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ873_002012"
     CDS             170..370
                     /locus_tag="VQ873_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108217.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ873_002013"
     CDS             412..816
                     /locus_tag="VQ873_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108218.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ873_002014"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ873_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3108219.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ873_002015"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ873_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3108220.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ873_002016"
     CDS             2697..4088
                     /locus_tag="VQ873_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3108221.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ873_002017"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ873_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3108222.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ873_002018"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ873_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3108223.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1215 c         1411 g         1969 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBOH010000080         6206 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOH010000080 DAVBOH010000000
VERSION     DAVBOH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.081"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ873_002019"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ873_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ873_002020"
     CDS             1555..2427
                     /locus_tag="VQ873_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3108224.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ873_002021"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ873_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ873_002022"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ873_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ873_002023"
     CDS             3376..4092
                     /locus_tag="VQ873_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3108225.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ873_002024"
     CDS             complement(4222..5037)
                     /locus_tag="VQ873_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3108226.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ873_002025"
     CDS             complement(5034..5939)
                     /locus_tag="VQ873_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3108227.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1961 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagta
//
LOCUS       DAVBOH010000081         5902 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOH010000081 DAVBOH010000000
VERSION     DAVBOH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.082"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            61..1887
                     /gene="glpO"
                     /locus_tag="VQ873_002026"
     CDS             61..1887
                     /gene="glpO"
                     /locus_tag="VQ873_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3108228.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1957..2661
                     /locus_tag="VQ873_002027"
     CDS             1957..2661
                     /locus_tag="VQ873_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3108229.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2958..3161
                     /locus_tag="VQ873_002028"
     CDS             2958..3161
                     /locus_tag="VQ873_002028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108230.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3248..3508)
                     /locus_tag="VQ873_002029"
     CDS             complement(3248..3508)
                     /locus_tag="VQ873_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108231.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(3563..3907)
                     /locus_tag="VQ873_002030"
     CDS             complement(3563..3907)
                     /locus_tag="VQ873_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108232.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            4944..>5902
                     /gene="ltrA"
                     /locus_tag="VQ873_002031"
     CDS             4944..>5902
                     /gene="ltrA"
                     /locus_tag="VQ873_002031"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3108233.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         1836 a         1141 c         1295 g         1630 t
ORIGIN      
        1 agattttcga agagtataat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat
       61 atggaatttt caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg
      121 gacctcttga ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct
      181 agcggtcttg agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt
      241 tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac aattcgacgt agaggtggtc
      301 tcagatacgg tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaacca
      361 gatccaatgc tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt
      421 aaagtagcca tggacttgta cgacctttta gcaggtgtga gcaacacacc aactgcgaac
      481 aaggttttga gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg
      541 gtaggaggtg gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac
      601 atcaaacgtg ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc
      661 ctctttgacg aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa
      721 gtatttgaaa tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta
      781 cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac
      841 ttggtagtgg attcaagcaa aatcaaggtt tcacagccag tttactttga cacaggtttg
      901 ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact
      961 gatacagact acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat
     1021 ctacttggca ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa
     1081 agcagctggg caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt
     1141 ggaaataacg gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct
     1201 tatctctcca aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt
     1261 agcacatctg agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt
     1321 gatgacaatg gtctcttgac tcttgctggt ggtaaaatca cagactaccg taagatggct
     1381 gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa
     1441 ttgatcaatt ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat
     1501 tcagaaatcg aagcctttgc gcaacttgga gtttcacgtg gtttggatag caaggaagct
     1561 cattacctag caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc
     1621 ttggaacaag cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc
     1681 aatgagttga ctcttagccc agttgacttc cttcttcgtc gtaccaatca catgctcttt
     1741 atgcgtgata gcttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat
     1801 gactggacag aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac
     1861 aacgatttag cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct
     1921 tgtcgcccgt cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa
     1981 tttctaggga ctttaattct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt
     2041 cctaaaacca agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca
     2101 gttgcggttg cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg
     2161 accatcggtg tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta
     2221 gcccagttcg caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac
     2281 tatgaggcag aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc
     2341 aaggatactg tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca
     2401 atctttgctt tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact
     2461 ttgattgtcg gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct
     2521 cgtgaccttg gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga
     2581 gactggtctt acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg
     2641 cttgtattct cacttttcta gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg
     2701 tcgccttacc gtactcaagt acagcttgcg gctagcttcc tagtttgctc tttgattttc
     2761 attgagtatt agaaaacaat tatgttgata gagcttgggc aagagcccaa tttcagcaaa
     2821 aaatgaagta aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg
     2881 tcaactacag tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc
     2941 aagcacctgc aagcaacgtg ccgaaatggt caaatcctga ttatgtcaac gaattagacc
     3001 caaaaatcgt tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg
     3061 aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg
     3121 aggataaaaa acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc
     3181 ttacaaatta cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt
     3241 ttatatttta gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt
     3301 ttctatagta ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg
     3361 ttatgtagta tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa
     3421 aatatgctcc accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa
     3481 tcatataact gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc
     3541 catgtattgt gttgacgtaa tttcaaacat taggatcgta tgatctaaaa gatatattta
     3601 ggtcgatttc attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag
     3661 cacgtcgttc aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc
     3721 ttaaaatatt tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct
     3781 caccagatac aactttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
     3841 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
     3901 tagacataac ggaaactctt ttgtattttt gatttttttc aacttttatt atacaataaa
     3961 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
     4021 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
     4081 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
     4141 tcattcgctt gggtctgctc tacaataaaa aacaataaaa aataaataga cgtattttca
     4201 aaaaaaaaaa atgcatattt atcttagcaa aatgacgatt taaatcgtcg tttttttgta
     4261 gtacgacggg catgtcgtat atctgaggtg taagtcctcg gtgggcacct gctaccggtg
     4321 aacccaatag cgattcccaa gcctgactat cgtgaggtag cagggagagg aagggatagc
     4381 gaaatcgtgg ctctacgaac aggaacgtga tagtaaggcg tatatagcgg ataaggaggc
     4441 ttcaaactct aaagtccaaa aaggtagtcg taacctatat gtgtaaatca cgagagtaat
     4501 tgaattcgga ctaaggtttg tgtgaaaaag ataaatcttt ctagagtcta aagactctgc
     4561 gtcagatttc ctattttcac tgtaaccttt taacgtcctc atatcttgta taaacgagga
     4621 aagatgtacg acttatcccg tgaggtttca tgagcgctga aagcgtagta acaacgaatc
     4681 atgagaagtc agccgagccc atagtagtga ggaaacttct gtagtggaag tggagcgacg
     4741 gggtgaatac tcaaacagtc tggggagaga ctgtttgagg tctgtcgcta gaaagagaaa
     4801 acgacagatc gaagtaatcc tacttcactt gtgtctgtaa aatgagtggt ctgatagaac
     4861 tggactttga cacgtaatga ctagatgaag gttcaccaat ataagatgtc cctcaggcac
     4921 caaaacaaga aaggaatagg cacatgtcaa aactgctaga taagatatta tcacgcgaaa
     4981 atatgctgga agcctacaat caagtaaaat ccaataaagg ctcagctggg attgatggaa
     5041 tgactatcga agagatggat aattatctca gacaaaactg gcgcttgact aaggaactga
     5101 taaaacagag aaaatataag cctcaaccag ttcttaaagt tgagatacct aaaccagacg
     5161 gaggcatccg tcaactagga attccaacag ttatggatag aatgattcaa caggccattg
     5221 tccaagtcat gagccccatt tgtgaacccc atttctcaga tacgagttat ggtttcagac
     5281 caaataggtc atgtgaaaaa gccatcatga agctcttaga atacttaaat gacggctatg
     5341 agtggatagt ggatatagac ctagagaaat ttttcgatac agttcctcaa gatagattga
     5401 tgtccttagt acataacatt atcgaagacg gagatacgga atccttgatt cgtaagtatc
     5461 ttcattcagg tgttatcatt aatggtcaac gttataaaac actagttggt acaccacagg
     5521 gaggaaattt atctcctctc ttatccaata tcatgcttaa tgaattggac aaggaattag
     5581 aaaagagggg acttcgattt gtgcgctacg cagatgattg tgtgattacg gtcggaagcg
     5641 aggcagcctc taagcgtgtg atgtattcag tcagtcgttt tattgagaaa cggctaggtt
     5701 tgaaagtaaa catgaccaag actaagatta ccagaccaag agagttgaaa tatctaggtt
     5761 ttgggttctg gaaatcatca gatggttgga aaagccgtcc acatcaagat agtgttcgga
     5821 gatttaagtt taaattgaag aaactaacac agaggaaatg gagtatagac ctaacaagac
     5881 gtattgagca actgaatttg tc
//
LOCUS       DAVBOH010000082         5468 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOH010000082 DAVBOH010000000
VERSION     DAVBOH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.083"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..1143
                     /locus_tag="VQ873_002032"
                     /pseudo
     CDS             1..1143
                     /locus_tag="VQ873_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            1167..1323
                     /locus_tag="VQ873_002033"
                     /pseudo
     CDS             1167..1323
                     /locus_tag="VQ873_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1316..1489)
                     /locus_tag="VQ873_002034"
     CDS             complement(1316..1489)
                     /locus_tag="VQ873_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3108234.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(1648..3255)
                     /locus_tag="VQ873_002035"
     CDS             complement(1648..3255)
                     /locus_tag="VQ873_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3108235.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            3408..4892
                     /locus_tag="VQ873_002036"
     CDS             3408..4892
                     /locus_tag="VQ873_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3108236.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4987..>5468
                     /locus_tag="VQ873_002037"
     CDS             4987..>5468
                     /locus_tag="VQ873_002037"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3108237.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1616 a         1238 c         1002 g         1612 t
ORIGIN      
        1 tcaaaaacct tctaaaattc cttatcttga aacaactggt atgcctacta gaattctcct
       61 tagaaagcgt cgctttaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat
      121 cgtcaagaaa aatcaccaaa ttcctcgtat tatcaaccaa aaaattgcgc aaaagttaat
      181 tgaaaagaat tctatgaccg atattgccca tcagctggcc atctcaactt caactgttat
      241 tcgtaagctc aatgattttc actttaaaca tgatttttct tgtcttcctg agattatgtc
      301 ttgggatgag tatgctttta caaagggaaa gatgagcttc attgcgcaag attttaacaa
      361 gctcaatatc atcactgttc ttgagggaag aacacaagct atcattcgaa atcactttct
      421 tcgctacgat agagctgtcc gatgtcgcgt caaaattatt actatggata tgtttagccc
      481 ttactatgac ttagctaaac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc
      541 tcctagactg tttcactccc gaatgctaaa atcgttcttg atcgctttca tattgtacaa
      601 catcttagcc gtgctatgag tcgtgtgcgt gttcaaatca tgaatcagtt tcatcgaaaa
      661 tcccatgaat acaaggctat caagcgctac tggaagctca tacaacagga tagtcgtaaa
      721 ctcagcgata aacattttta tcgccctact tttcgtatgc atttaaccaa taaagagatt
      781 ttaaacaagc ttttgagcta ttcacaagac ttgaaacatc actatcagct ctatcaactc
      841 ttgctgtttc actttcagaa taaggaaccg gagaaatttt tcggactcat tgaggacaat
      901 cttaagcagg ttcatcctat ttttcagact gtctttaaaa cctttctaaa ggacaaagag
      961 aaaatagtca acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat
     1021 ctcatcaaac ttatcaagcg caatgccttt ggttttcgga actttgaaaa cttcaaaaaa
     1081 cggattttca tcgctctgaa catcaaaaaa gaaaggacga aatttgtcct ttctcaagct
     1141 tagcttttct tcaacccact acagttgaca aagagcctaa gcttttacct cttcctccct
     1201 actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag cacctcataa
     1261 aaggtattac caagttgcaa taccttttat gaggctcttt tgtcttgttc ttgtttcaat
     1321 tgactatatt atcagtgtaa tagtctaata gatagttaaa tgtagttgga tttccactaa
     1381 aggttgatga gtaagttttt gtatctgaac ctgattggcc gcaagcagct aaaagcaaaa
     1441 cagatgcaaa agtcaggcct gcactaagga cacgcttctt tatgttcatc ttctttctcc
     1501 ttaatagtgg gaatttgtaa agttaattga atttcgagaa tgaaagttta taaaccttgg
     1561 ttataaaaaa caaaggattt ctgcttttta tacagtcctc ccttgttttt atatgatttc
     1621 aattttaaat ttttctgcaa aaaatattta tagtaattcc acacagaaag catcccatgg
     1681 aactaagatt tgtttttcaa agacttcttg agctagggtg ttttcaatca agacagattt
     1741 gacttttcct tctactgtca agtcttgctc ttcattggac aagttagcca caactaggaa
     1801 gcgacggtcg ccatccttac gtatataagc aaagacctta tcagccgtat caagcaattc
     1861 aaagtcagct cgaactagcc agctattctc cttgcgaatt tggaccagtt tctgataggt
     1921 atagaaaata gaatctggat ttgccagcgc ttcttggaca ttgatcatct cgtaatttgg
     1981 attaaccgcc aaccaaggtt gacctgttga gaaaccagcg tttttgctct cgtcccattg
     2041 cataggggta cgggcattgt cacgtccaat aacacggata ctgtccatga tttcttcaat
     2101 cggaacacct ttttcaagag cctcacgcgc atagttgaga gattcaatat cttctacttg
     2161 atccagcgtt tcaaagggat agttggtcat gccaatttcc tcaccttggt agatataagg
     2221 agttcctctc atgagatgaa gcaagatggc aaaggctttg gcagattttt cgcggtattc
     2281 ttggtcattt ccccagattg agacaatacg agggaggtca tggttgttcc agaagaggga
     2341 attccagccg tcctcaactc ctaactctgt ctgccatttg ttgaagattt cttttaactt
     2401 agcgatattc agctcttttt gatagtgcca tttaggctga ccttcctgat actgaagacc
     2461 gatatgttca aactggaaga ccatagacaa ttcttgcccc tttggatcag agtagagctt
     2521 ggcaatctct ggcgttgctc cccaagtctc ccctactgtc aagagatcct tatctccaaa
     2581 ggtcgcctga ttcatttcct tgagataggg atggagcata ggaccattat tgactacctt
     2641 ctcgtcagga attttgccaa tcatgtcaat aacatccata cggaaaccac caataccctt
     2701 atcaatccag aagttcatca tctcataaat tttctggcga agtttttcat tttcccagtt
     2761 gagatccggc tgtttcttgc tgaaaaagtg gagatagtat tgacctgact tttcatcgta
     2821 ttcccaagca gacccactaa agatagaatc taggtcattg ggttcatcgc gccagatata
     2881 gtagtctcgc tcagggctat taggattttc acaggcctct acaaaccagg catgctcatc
     2941 cgaggtatga ttgaccacca agtccatgat gatacggata tcacgcttct tagcttctgc
     3001 aatcagttga tccatatcct ccatggttcc aaaaatcgtt gcaatcgctt gataatcagc
     3061 aatatcgtag ccattatcat ccatagggct gtcataaacg ggagaaagcc aaattgctgt
     3121 gattcctagc ttggctagat agtccaactt actggtaatt cctggcaaat cgccaattcc
     3181 atctccatta ctatccataa aactctttgg atagacttga tagactacgg cattgtgcca
     3241 ccatttttct tgcatcttct tacctcatta ttttcataat ctatagtcta tgatagcact
     3301 ttttaaaatt ttgtgcaagc gtttgcttaa tctttttaat ttctttttta gctccgtagt
     3361 ttcctaactt ccaatttttt attataatag agtccagagg taaaaaaatg aaaaaacaag
     3421 cttttagttc tgaacaatat ttgaatttac aacgcgacca tattttggag cgcattaacc
     3481 aatttgacgg caagctctac ttagagtttg gcggtaaaat gttagaagat ttccacgctg
     3541 ctcgtgtcct tcctggttat gaacctgaca acaaaatcaa gctcttgcaa gaattgaaag
     3601 agcaggttga ggttgtgatt gccattaatg ctagcaacat tgaacattcc aaagcacgtg
     3661 gcgacttagg catttcttat gaccaagaag ttcttcgttt gattgacaaa ttcaatgaat
     3721 tagggatttt tgttggttcc gttgtcatta cacaatacgc tggccaaccc gctgcagatg
     3781 ccttccgcaa tcaacttgag aaaaacggaa ttgattctta tcttcattat ccaatcaaag
     3841 gatatccgac ggatatggat cacatcattt ccccagaagg catgggcaaa aacgactaca
     3901 tcaaaaccag tcgcaacttg attgtcgtaa ccgctcctgg acccggttct ggaaaattgg
     3961 caacgtgtat gtccaatatg taccacgacc aaatcaatgg catcaagtct ggctacgcta
     4021 aatttgaaac cttccctgtt tggaatcttc cccttcatca cccagttaac ttggcttatg
     4081 aagctgccac agctgacctt gatgatgtca acatgattga ccccttccat cttcaaacct
     4141 atggagaaac cactgtcaac tacaaccgtg atatcgaaat cttcccagtg ctcaagcgca
     4201 tgttggaacg tattctcgga aaatcaccat acgcttcacc gacagatatg ggtgtcaaca
     4261 tggttggttt cgctattaca gatgacgagg ctgctgtcga agcttctaaa caagaaatca
     4321 tccgccgtta ctatcaaaca gttcttgact tcaaagctga aaaagttggc gaagctgccg
     4381 tcaagaaaat tgagttactc atgaacgacc tcggtatcac acctgcagac cgtaaggttg
     4441 ctgtcgttgc gcgccaaaaa gcagaagaaa ctggtggacc agccctagcc tttgaattgc
     4501 caaatgggga aatcatcact ggtaagaact cagaactctt tggccctaca gccgctgcct
     4561 tgatcaatgc catcaaaaaa tcagctgaca tcgctaaaga agtaaaacta atcgagcctg
     4621 aagttgttaa gccaatccaa ggtcttaaaa tcgatcatct cggtagccgc aatccacgcc
     4681 ttcattcaaa tgaaatcctg attgcacttg ctatcacagc tacagaaaat cctgatgctg
     4741 cccgcgctat ggaagaactc ggcaacctca aaggaagcga agcccactca accatcatct
     4801 tgactgatga agacaagaat gtccttcgta aactgggtat caacgtaacc tttgacccat
     4861 actaccaata cgaccgctta tatcgtaagt aaagatttca acctctccag cctcggagag
     4921 gttttctctc tgtctcagga gcaaccttta tgatataatg agagaagaaa actgaaagga
     4981 tttaccatgt caaaagaagt tattgtcgaa agttttgaac ttgaccacac cattgtcaaa
     5041 gcaccctatg ttcgcttgat tggggaagaa acaggaccaa aaggagacat catctccaat
     5101 tatgatattc gcttggtgca accaaacgaa gactctatcc ctactgccgg ccttcacact
     5161 atcgagcacc tcttagccaa actcatccgt acccgcattg acggcatgat tgactgttca
     5221 ccatttggtt gccgcacagg cttccacatg attatgtggg gacgtcacac cagtgctaaa
     5281 atcgcagctg ttatcaagga ttcgctcaag gaaatcgctg aaactactac ttgggaagat
     5341 gtcccaggga caaccatcga atcttgcgga aactacaagg accacagcct cttctctgct
     5401 aaagaatggg caaaactcat cttggaacaa gggatttcag atgatgcctt tgaacgtcat
     5461 gtgattta
//
LOCUS       DAVBOH010000083         5440 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOH010000083 DAVBOH010000000
VERSION     DAVBOH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.084"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ873_002038"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ873_002038"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3108238.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="VQ873_002039"
     CDS             complement(1663..3090)
                     /locus_tag="VQ873_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3108239.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="VQ873_002040"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="VQ873_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3108240.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="VQ873_002041"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="VQ873_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3108241.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(5324..>5440)
                     /locus_tag="VQ873_002042"
     CDS             complement(5324..>5440)
                     /locus_tag="VQ873_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108242.1"
                     /translation="SQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         1572 a         1288 c         1066 g         1514 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaagttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc catttgcatg gtgtcgatga tgtcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgctt
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtgtttcc tctttacact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggtgtctg
     1741 ttccttctta tgaatagggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaagaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaagataga agatattgtc
     2401 aaaataccct cgcattttct cttctataac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccgcag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcactaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttatccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgatagcact gaaaccgtcc gcactgctca agaaaaacat caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgccag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggtgcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaata ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatagc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcggac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgaca tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc ttaatagttt
     5101 aaaacccgta actctcttaa agagcctctt gaatgccgcc attctttcct catcaaaaaa
     5161 actccgtagt ctctagcgct ataaatccgg ctagagatta cagagttatt ttttaatcta
     5221 aacttcctac aagggtatat tatctactga aaggatatgg tatttgtagg gaatacttta
     5281 aagagttctt acaggaagtc agtattaact agttatatta ggtttagttt acccattcac
     5341 cattggcatt gactccatag ccatctacag ttgtgttgac tgcaagggca cctgagccat
     5401 tgacatagta ccatttatct gatactttga accattggct
//
LOCUS       DAVBOH010000084         4996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOH010000084 DAVBOH010000000
VERSION     DAVBOH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.085"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            298..1843
                     /locus_tag="VQ873_002043"
     rRNA            298..1843
                     /locus_tag="VQ873_002043"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1895..1967
                     /locus_tag="VQ873_002044"
     tRNA            1895..1967
                     /locus_tag="VQ873_002044"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1928..1930,aa:Ala,seq:tgc)
     gene            2092..4993
                     /locus_tag="VQ873_002045"
     rRNA            2092..4993
                     /locus_tag="VQ873_002045"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1407 a         1017 c         1469 g         1103 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gcgaaagcgg ctgtgatata ctaatatagt tgtcgcttga gagaagcgag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      301 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      361 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      421 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      481 agatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      541 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      601 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
      661 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
      721 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
      781 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
      841 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
      901 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
      961 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1021 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1081 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1141 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1201 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1261 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgacga ctctagagat
     1321 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1381 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1441 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1501 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1561 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1621 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     1681 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     1741 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     1801 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     1861 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     1921 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     1981 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2041 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2101 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2161 gatatgcctt gggtagctgt aagtaagcga tgatccatgg atttccgaat gggggaaccc
     2221 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2281 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2341 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2401 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2461 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2521 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2581 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     2641 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     2701 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     2761 tctgaatagg gcgccttggt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     2821 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     2881 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     2941 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3001 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3061 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3121 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3181 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3241 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3301 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3361 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3421 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3481 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3541 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3601 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     3661 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     3721 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     3781 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gactttaagt
     3841 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     3901 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     3961 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4021 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4081 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4141 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4201 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4261 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4321 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4381 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4441 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4501 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4561 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4621 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     4681 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     4741 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     4801 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     4861 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     4921 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     4981 aggacttatc caaagt
//
LOCUS       DAVBOH010000085         4647 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOH010000085 DAVBOH010000000
VERSION     DAVBOH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.086"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(80..517)
                     /locus_tag="VQ873_002046"
     CDS             complement(80..517)
                     /locus_tag="VQ873_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3108243.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ873_002047"
     CDS             complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ873_002047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3108244.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3491..3841
                     /locus_tag="VQ873_002048"
     CDS             3491..3841
                     /locus_tag="VQ873_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3108245.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4056..4160
                     /locus_tag="VQ873_002049"
     CDS             4056..4160
                     /locus_tag="VQ873_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3108246.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4165..4398
                     /locus_tag="VQ873_002050"
     CDS             4165..4398
                     /locus_tag="VQ873_002050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108247.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
     gene            4525..>4647
                     /locus_tag="VQ873_002051"
     CDS             4525..>4647
                     /locus_tag="VQ873_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET3108248.1"
                     /translation="MEQLHFITKLLDIKDPNVQILNIINKDTHKEIIAKLDYDAP"
BASE COUNT         1424 a         1109 c          855 g         1259 t
ORIGIN      
        1 gcccgcggct agtttcctag tttgctcttt gattttcatt gagtataaca caaaaggtag
       61 cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct ctcttgatac
      121 agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc gcttttaaac
      181 tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca
      241 catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga aaaggaattt
      301 cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc ttgggattga
      361 ctgggatgat tttatagccc cgagcctgca tttcctttgt cactcgattg ctggttgttt
      421 cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga tactgacgaa
      481 tcacgccatc acttggattg ataaattctt gactcataga aaacctcctt tttcatcagt
      541 atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac tagccccctt
      601 tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga ggaacactga
      661 gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc aattcagatt
      721 taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc tgataaccac
      781 ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct gctgccgaac
      841 cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg
      901 aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag cccttatcac
      961 gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg
     1021 tatcaatgta ggctttggct tccttacgac taattcccaa attattagac aagccaaagt
     1081 ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacga tcatttgcag
     1141 tcacattatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta tggatatctg
     1201 ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc aaaacgcgca
     1261 attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct ggcacaaaag
     1321 ccttccgaat caagcgccct tgttccaatc gggcaggaat attttgcaag tttggatcca
     1381 cactagacaa acgcccggtc tgggtcaaat cctgcatata gcgagtatga atctttccat
     1441 cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta gcaatttgac
     1501 ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc aacacatcca
     1561 ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt cccaatttct
     1621 caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca ccagccagct
     1681 cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc atctcaagca
     1741 aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca aaagccagag
     1801 gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt tcaagtaaaa
     1861 taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag aatttctcac
     1921 gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca accaagtaag
     1981 tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt
     2041 atttagccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa
     2101 gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag aaatccttga
     2161 aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcttatcc ccacaagacc
     2221 aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca aagtggaaga
     2281 tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa tccaaactct
     2341 cagacacatc agctgacgac acatttaaag cctgctttag ctgtttgaag cccatctcat
     2401 cgtagaattt cccaagattt tcaacatctg gaccactata gaccaagtcc tctaaaccaa
     2461 tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agataaaaag gcctgttcct
     2521 tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata ttttcataaa
     2581 tcccctcaag cgaaccatgc tccagcaaga gcttaatacc cgtcttttca ccgactttgg
     2641 tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg ataaactgag
     2701 ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca aactcagcca
     2761 cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc aaatccttgt
     2821 ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa
     2881 tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata tgatccagca
     2941 actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc cgaccaccct
     3001 tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa
     3061 tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactgaaaa ccataaatcg
     3121 cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa
     3181 acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta tccatacacc
     3241 cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag tatttttcaa
     3301 actttttccg aataaataga tagagccaga gaatttagta aacctagatt taaaaatgtg
     3361 ctataatata gtatattgaa tctataatag tacaccttga ctgctaaaat atttctataa
     3421 attaatttga ctttcctgat agagttattc acatcttatt tcaactcact atagaaggag
     3481 gaataggagg attctcagac atccgggcat cagcccaact aatgatttga ttgctaagaa
     3541 aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg acttgccagc
     3601 aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca tgccttactc
     3661 ggtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg gtactcaagt
     3721 aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt gggcttacct
     3781 gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg atactcacta
     3841 gatctacaaa cacatcgctc ctgtttacgt cattgctatc gtggatagta attatttctc
     3901 agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg aggtattggc
     3961 gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg aattaaaaaa
     4021 tacagagaaa ccagcaaaga caaggttcgc aagccatggt tggagttttt cggcaacaag
     4081 ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct ggactacaag
     4141 agctggtccg aggaggatag gaaaatgttt agtcaactac gtatgcgaga agaacaagcc
     4201 ttgttagcgc aggactatgc cttggaaact gctagggcgg gaggtattga acaaggctta
     4261 gagcgtggga aagttgaagg aagggaagaa aggaaacttt ttgccttcct agacatagta
     4321 cgccaagatc ttctgacttc tgaggttgcc agccagcaat taggtatgtc agtatctgaa
     4381 tttgaggcac tgttgtaaaa tggctccata atatccatag tgggtaaatc ccctatggat
     4441 attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
     4501 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     4561 attaaagacc ctaatgtcca gattttaaac atcatcaata aggatacaca caaggaaatc
     4621 atcgccaaac tggactacga cgcccca
//
LOCUS       DAVBOH010000086         4609 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOH010000086 DAVBOH010000000
VERSION     DAVBOH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.087"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..273
                     /locus_tag="VQ873_002052"
     CDS             <1..273
                     /locus_tag="VQ873_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3108249.1"
                     /translation="SWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYY
                     LEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            674..1795
                     /gene="mnmA"
                     /locus_tag="VQ873_002053"
     CDS             674..1795
                     /gene="mnmA"
                     /locus_tag="VQ873_002053"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3108250.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1936..2391
                     /locus_tag="VQ873_002054"
     CDS             1936..2391
                     /locus_tag="VQ873_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3108251.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2401..4314
                     /gene="mnmG"
                     /locus_tag="VQ873_002055"
     CDS             2401..4314
                     /gene="mnmG"
                     /locus_tag="VQ873_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3108252.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1337 a          933 c         1125 g         1214 t
ORIGIN      
        1 tcatggtact acctaaacgc taacggtgct atggcaacag gttgggctaa agtcaacggt
       61 tcatggtact acctcaacgc taacggttca atggcaacag gttgggtgaa agatggagat
      121 acctggtact atcttgaagc atcaggtgct atgaaagcaa gccaatggtt caaagtatca
      181 gataaatggt actatgtcaa tggcttaggt gcccttgcag tcaacacaac tgtagatggc
      241 tatgaagtca atgccaatgg tgaatgggtt taagccgatt aaattaaatc atgttaagaa
      301 catttgacat tttaattttg aaacaaagat aaggttcgat tgaataaatt tatgttcgta
      361 ttctttaggt acctatctta tgatttcagg aaatgtcatt aaaaaaacga ctccttttct
      421 ctaacttgaa aaatagatta gagaaaatgg gttgttttat ttattatagt tatttgaatg
      481 aagataagaa gaaggtatac tcacatcatt cacataatct gtatattgac tataagtttt
      541 aaaaaacaat ttttaagctc ttccttgtct tctctaacca agcgtgttat aatgaatact
      601 gctcaagcga ccttcaatcg tgaagcacac acgaccttca atcgtgaata aacgaataga
      661 tgggagactt accatgagtg ataactctaa aacacgtgtt gtcgtgggga tgagtggtgg
      721 tgttgattcg tcggtgacgg ctcttttgct caaggagcag ggctacgatg tgatcggtat
      781 cttcatgaag aactgggatg acacagatga aaacggcgtc tgtacggcga ccgaagatta
      841 caaggatgtg gttgcggtgg cagaccagat tggcattccc tactactctg tcaattttga
      901 aaaagagtac tgggaccgcg tttttgagta tttcctagcg gaataccgtg cagggcgcac
      961 gccaaatccg gacgttatgt gcaacaagga aatcaagttc aaggcctttt tggactatgc
     1021 catgaccttg ggggcagact atgtagcgac tgggcattat gctcgagtgg cgcgtgatga
     1081 ggacggcact gttcacatgc ttcgtggcgt ggacaatggc aaggaccaga cctatttcct
     1141 cagccaactt tcgcaagaac aacttcaaaa aaccatgttc ccactaggac atttggaaaa
     1201 gcctgaagtt cgaaaactag cagaagaagc aggcctttcg actgctaaga agaaagactc
     1261 gacagggatt tgctttatcg gagaaaagaa ctttaaaaac ttcctcagca actacctgcc
     1321 agctcagcct ggtcgcatga tgactgtgga tggtcgcgat atgggcgagc atgcaggtct
     1381 gatgtattat acaatcggtc agcgtggcgg actcggtatc ggtgggcaac acggcggtga
     1441 caatgcccct tggttcgttg tcggaaaaga tctaagcaag aatattctct atgtaggaca
     1501 aggattctac catgattcgc tcatgtcaac tagcctagaa gccagtcaag tccactttac
     1561 tcgtgaaatg ccagaagagt ttacgctaga atgtacggct aaattccgtt accgtcagcc
     1621 tgactctaag gtgaccgtcc atgtcaaagg agacaaggca gaggtcatct ttgcggaacc
     1681 acaacgcgcg attacaccag gccaggcagt tgtcttttac gatggcgaag agtgtctagg
     1741 tggtggtttg attgacaatg cttaccgcga tggacaagtt tgtcagtaca tttagattga
     1801 caaattttct caatttgcta caataataac agcaatagaa atgatggtca aagctcatgg
     1861 atgttgcagg cttttttgtc ctgcacttct ttggagtttt gactgttttt gtgtcgttta
     1921 agggaaagga caagaatgac tcaacaagac tttcggacaa aagtagacaa tacggttttt
     1981 ggtgttcggg cgacagcttt gattcttcaa aatcacaagc ttctagtcac caaagacaag
     2041 ggcaagtatt acactatcgg cggtgcgatt caagtcaatg aaagcacgga agacgcggta
     2101 gtccgtgaag tgaaggaaga actgggtgtc aaagctcaag ctgggcagct agcttttgtg
     2161 gttgaaaatc gttttgaaca ggacggtgtt tcctatcaca atatcgagtt tcattatctg
     2221 gtggacttac ttgaggatgc cccattgacc atgcaggaag atgagaaaag gcagccctgt
     2281 gagtggattg acttggataa gcttgaggat atccagctag ttccagcctt tttaaaaacg
     2341 gccctaccag attgggaagg ccaactaaga cacattcatc ttgaggaata ggagagaaac
     2401 atgacttatc attttactga agaatacgat attattgtaa ttggtgcggg acacgctggg
     2461 gttgaggctt ccttggccgc tagccgtatg ggctgtaagg tcctgcttgc gaccatcaat
     2521 attgaaatgc tggctttcat gccttgtaat ccctctatcg gtggttctgc taaggggatt
     2581 gtcgtacgtg aagtcgatgc cctcggtggc gagatggcca agaccattga caagacttac
     2641 atccagatga agatgctcaa cacagggaag ggcccagccg ttcgtgccct tcgtgcgcag
     2701 gctgataagg aactttactc taaggaaatg cgcaagacag ttgaaaatca agaaaatctg
     2761 acccttcgtc aaaccatgat tgatgagatt ttggtggaag atggcaaggt tgtcggtgtg
     2821 cgtacagcca cccatcaaga atatgctgct aaggctgtta ttgtgacgac agggactgct
     2881 ctccgtgggg aaattatcat cggagacctc aagtactcat caggtcctaa ccacagcttg
     2941 gcttctatta acctagctga caatctcaag gaactgggtc tcgaaatcgg tcgtttcaag
     3001 acaggaaccc ctccacgtgt caaggcttct tctatcaatt acgatgtgac ggaaattcag
     3061 ccaggagacg aagtgcctaa tcatttctca tacacttcac gtgatgagga ttatgtcaaa
     3121 gatcaagtgc catgctggtt gacctatacc aatggtacca gtcatgagat tatccaaaac
     3181 aacctccacc gtgcgcctat gtttacaggt gtggtcaagg gagtggggcc tcgttactgt
     3241 ccgtcgattg aagacaagat tgtgcgcttt gcggacaagg aacgtcacca actcttcctt
     3301 gagccagaag ggcgcaatac tgaggaagtc tatgttcaag gactttcaac cagtctgcct
     3361 gaggatgtcc agcgtgactt ggttcattcc atcaaaggtt tggaaaatgc agagatgatg
     3421 cggacaggtt atgctattga gtatgatatg gtcttgcctc atcagttgcg tgcgactttg
     3481 gaaaccaaga aaatctcagg tctcttcact gctggtcaga caaatggaac atcaggttat
     3541 gaagaagctg ctggccaagg gattatcgcg ggtatcaatg cggctctgaa aatccaaggt
     3601 aaacctgagt tgattctaaa acgaagtgac ggttatatcg gggtgatgat cgacgacttg
     3661 gtgaccaagg gaaccattga accttaccgt ctcttgacca gtcgtgctga ataccgtctc
     3721 attcttcgtc atgacaatgc tgatatgcgc ttgactgaga tgggacgcga gattggcctt
     3781 gtggatgatg aacgctgggc tcgttttgaa atcaagaaaa atcaatttga taatgagatg
     3841 aaacgcctag acagtatcaa actcaagcca gtcaaggaaa ccaatgctaa ggttgaggaa
     3901 atgggcttca agccgttgac agatgcggtg acagccaaag aattccttcg ccgtccagaa
     3961 gtttcttacc aagatgtggt ggccttcatc ggaccagctg cagaagactt ggatgacaag
     4021 attatcgaat tgattgaaac agaaatcaag tacgaaggct atatttcaaa agccatggat
     4081 caggttgcca agatgaaacg tatggaagaa aaacgcattc cagccaatat tgactgggat
     4141 gacatcgatt ctattgcgac ggaagctcgt cagaagttca aactcatcaa tccagaaacc
     4201 atcggccaag ccagccgtat ttcgggagta aacccagcag atatttctat tttgatggtg
     4261 tatctggaag gtaaaaatcg tagtatttct aaaactcttc aaaaatcaaa atgatacgtc
     4321 gtcggcttct tacgaatgag ttcaaagctt ggctttgatt catctccagc ctcccatagt
     4381 tccccgaact atgggagcta actcaagtta tgcattttcc tagccttctg gtctgatttt
     4441 cattgagttt taatctcaaa agaaagcata gagaaaaaca gctccgaaga cggagctgtt
     4501 ttgttgactt gtactcaatg aaaatcaaag agcaaactag gaagctagcc gtaggttgct
     4561 caaagcactg ctttgaggtt gtagatagaa ctgacgaagt cagctcaaa
//
LOCUS       DAVBOH010000087         4414 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOH010000087 DAVBOH010000000
VERSION     DAVBOH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.088"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..91
                     /locus_tag="VQ873_002056"
     CDS             <1..91
                     /locus_tag="VQ873_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3108253.1"
                     /translation="FSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(80..727)
                     /locus_tag="VQ873_002057"
     CDS             complement(80..727)
                     /locus_tag="VQ873_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3108254.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(836..1354)
                     /locus_tag="VQ873_002058"
     CDS             complement(836..1354)
                     /locus_tag="VQ873_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3108255.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1581..2450)
                     /gene="rsmI"
                     /locus_tag="VQ873_002059"
     CDS             complement(1581..2450)
                     /gene="rsmI"
                     /locus_tag="VQ873_002059"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3108256.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2453..2770)
                     /gene="yabA"
                     /locus_tag="VQ873_002060"
     CDS             complement(2453..2770)
                     /gene="yabA"
                     /locus_tag="VQ873_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3108257.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2810..3700)
                     /locus_tag="VQ873_002061"
     CDS             complement(2810..3700)
                     /locus_tag="VQ873_002061"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3108258.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3697..4335)
                     /locus_tag="VQ873_002062"
     CDS             complement(3697..4335)
                     /locus_tag="VQ873_002062"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3108259.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1219 a         1003 c          714 g         1478 t
ORIGIN      
        1 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
       61 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
      121 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      181 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      241 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      301 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      361 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      421 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      481 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      541 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      601 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      661 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      721 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      781 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      841 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      901 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      961 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
     1021 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1081 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1141 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1201 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1261 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1321 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1381 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1441 ctgctccaac catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1501 taccaagtga tacatcttta tattaccatc actaattaag ttaaacagaa acagacagaa
     1561 ttattacatt ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1621 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1681 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1741 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1801 ctttccagca attcagaaat ggtacctctt tggtattctt catagatttt agtcaattcc
     1861 ctgaccaaga ctaccgagcg gtcaccgtag acttctagca tattttccaa tgtatctgcc
     1921 acacgatggg acgattcata aaaaatctga gtttcaggat agtctttttt cgagtcgaaa
     1981 aattgctttt gctgacctga ttttctcggt aaaaagccgt aaaagatatg tggctgcggc
     2041 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg cacctggaac agtcacaact
     2101 gcaatttctt cctcaatagc tgccttaacc aaatcatgac cagggtctga aatgctaggc
     2161 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2221 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2281 tgcttgagca aaagacctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2341 aaggtctgga tagcgcgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2401 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcctactccc
     2461 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2521 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2581 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2641 ccaagcgaag agctgtattt tcctctacca ggctcttgag atttttcttg atggcttcca
     2701 catcggccaa ggttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2761 ttttgtccat aaaacagctc tttcctttct ttatcattca tttttgagtt tatatttctt
     2821 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2881 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2941 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     3001 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3061 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3121 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3181 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgggtc cgacttcgga
     3241 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3301 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3361 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3421 ccctaatgcg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatcgggaa
     3481 attctccctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3541 tatccgtaca aaagaggctc ttagctaaaa attgcgctat ttccaagctt ccaaagaaac
     3601 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3661 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3721 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3781 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3841 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3901 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3961 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     4021 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4081 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4141 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4201 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4261 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4321 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4381 aggggtttgt gacaatcttt ttgtcttctc attt
//
LOCUS       DAVBOH010000088         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOH010000088 DAVBOH010000000
VERSION     DAVBOH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.089"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ873_002063"
     CDS             complement(60..659)
                     /locus_tag="VQ873_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3108260.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ873_002064"
     CDS             complement(661..1758)
                     /locus_tag="VQ873_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3108261.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ873_002065"
     CDS             complement(1758..2495)
                     /locus_tag="VQ873_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108262.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ873_002066"
     CDS             complement(2497..3381)
                     /locus_tag="VQ873_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3108263.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ873_002067"
     CDS             complement(3368..3562)
                     /locus_tag="VQ873_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108264.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ873_002068"
     CDS             complement(3559..3765)
                     /locus_tag="VQ873_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108265.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOH010000089         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOH010000089 DAVBOH010000000
VERSION     DAVBOH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.090"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ873_002069"
     CDS             720..1712
                     /locus_tag="VQ873_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3108266.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ873_002070"
     CDS             1714..2532
                     /locus_tag="VQ873_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3108267.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ873_002071"
     CDS             2534..3319
                     /locus_tag="VQ873_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3108268.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ873_002072"
     CDS             3358..3636
                     /locus_tag="VQ873_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3108269.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ873_002073"
     CDS             3621..3818
                     /locus_tag="VQ873_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108270.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBOH010000090         3613 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOH010000090 DAVBOH010000000
VERSION     DAVBOH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.091"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..142)
                     /locus_tag="VQ873_002074"
     CDS             complement(<1..142)
                     /locus_tag="VQ873_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3108271.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGE"
     gene            complement(327..938)
                     /gene="rpsD"
                     /locus_tag="VQ873_002075"
     CDS             complement(327..938)
                     /gene="rpsD"
                     /locus_tag="VQ873_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3108272.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1133..2185)
                     /locus_tag="VQ873_002076"
     CDS             complement(1133..2185)
                     /locus_tag="VQ873_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3108273.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2182..2880)
                     /locus_tag="VQ873_002077"
     CDS             complement(2182..2880)
                     /locus_tag="VQ873_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3108274.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3047..>3613)
                     /locus_tag="VQ873_002078"
     CDS             complement(3047..>3613)
                     /locus_tag="VQ873_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3108275.1"
                     /translation="DAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRA
                     NGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVT
                     PMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQT
                     SMASIGLLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          988 a          806 c          699 g         1120 t
ORIGIN      
        1 gctctcctgt tttctctttt agctttaacc agccataaat ggtattacgt gagatttgga
       61 aaacgtgtga tgcttctgtt atactacctg ttcgctcaca ataagagaga acttttttac
      121 gaaaatctat tgaatatgcc ataaaagatt ataccacatt gtgtactatt tttggttcat
      181 tttactatat cactttggac tatatcggtc tagttatgtc tcaacgatta tagctggata
      241 ctaagagaaa tcaaaaaagc actaagggag aacgtcccaa agtgcttaat atcaaggcct
      301 caaagcctgt cttattcaat aaaatattac aacatcttgt tgtagaattc aacgacaagt
      361 gcttcgttga tttctgggtt gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc
      421 aacttttcag cgtcgaatga tacgaatgct ggacgtccaa gagtagcttc tactgcttca
      481 aggattgctg gaactttcaa tgatttttca cgaactgaga tcacttgacc tggagttacg
      541 cggtatgatg ggatatcaac gcgtttcccg tcaacaagga tgtgaccgtg gtttacgaat
      601 tgacgagctt gacgacgagt agtcgcgaga ccaagacggt aaacaacatt atccaaacga
      661 cgttccaaaa gaagcataaa gttgaaacct aggattccac ctttgatttt tgtagcttgt
      721 acgaacaagt tacggaattg tttttcacct acaccgtaag tgaaacgaag tttttgtttt
      781 tcagccaatt gcaaaccgta ttctgacaat ttagaacggt tgtttggtcc gtgttgtcct
      841 ggtacgtagt tacgacgtgc caattcttta cctgtacctg taagtgaaag gccaaggcga
      901 cgagcttgtt tccaagatgg tcctgtataa cgtgacatat gaatgtcctc ctgatataaa
      961 taatatttcg gtggaaatag tcacttagaa agccctgatt cgtgcagatg cccttcgcct
     1021 aaacagccaa ggttacttat cataagacac ctgttgacga gcttcatgct ttcctgctga
     1081 tatttcacac aaaatccatt ctaccatgaa tagctggatt tgtaaagggg ttttaggctt
     1141 tattttcact accagagagg ttgagaacga gggtaaaggt acttcctaga ccgtactggc
     1201 tgctgactgt gatttcccca cccaattgat gggccaattc acgcgcaatc gcaagtccta
     1261 atccatgacc acctgtcttc atgttacgcg aagtttcgac acgataaagg cgtttgaaaa
     1321 tattttccaa atcctctggg gcaatgccct gcccttcatc ggtcacactg attgaaagct
     1381 ggtccttctc cagcttagcc accacttcca gcttggttcc tggagcagaa tatttaaaag
     1441 cgttatcgac cagattcacc aagatacgag aaagcttagc ataatctccc tcaatccggg
     1501 cagactctgg gattacctgc aagtggacat ctcttctctc ctgctcaatc aaaaactgaa
     1561 attcactcat gcactcaatt aagagcttgt ccagaaaaat actgtcttta ctggtagttt
     1621 ccacctgatt tctagctgtg tttagggtca aaaaattcaa ctcctcaacc agtttattga
     1681 gcctctccgt ctggcgtcca atggttgcta gataatgagc ttgctccgac tccttgataa
     1741 tcccatccaa aatcccttct accgtcgctt ggatcgaagt gataggagtc ttaatatcat
     1801 gcgacaactg agcaatcatc aagccctttt ctcgttcgct ttcttccaag gaatcaaagc
     1861 ttacctgcaa atcatgggac atctcattaa aagtttgccc taattgctga aattctacag
     1921 gaccttgaac ctccaaattt gaaggaaaat ccttggccgc tacccgcttg gcatgctcct
     1981 tgagtttgcc caacgacgta aagactggca ataggagaaa gagactaatc ccagcaccga
     2041 caaggctggc aacgatggtc atcccaagca aaaagtaaat ctcgcctttc gcaatcagca
     2101 ttttttgaac agcccaaaaa acaaccaaaa tggttaagag ggttgaaata atatatccaa
     2161 ccaaaatata actttttagt ttcatgtttg tcctctcggt ttctctatct tatatcccaa
     2221 cccccaaact gtcttaatag tgggcgtttg gtcactacta tattttgcca gctcctgtcg
     2281 aagagcatgg atatgcacat tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat
     2341 cttttcatag aggtctgtct tggagaaaac tcgctctgga ttgctagcta aaatccacag
     2401 caattcaaat gatttaacag ttaaatccag catttcttct cctatttgaa cttcatgact
     2461 actatgattc atttttagat tgccaaggga aatcagctct gtttcgcccc cacgatgaag
     2521 gcggcgcaaa atattgtgga cacgcaaaac cagttcacgt gggctaaaag gcttagcaat
     2581 aaaatcatct gctcccaagc tcaggccgta aatcttgtcc tgttcactgg tcttagcagt
     2641 aataaatagg aaaggctgct ctggtgataa gtattgaacc tcactgatta aatcataacc
     2701 atccatccga ggcatcatga catctgtgat aatcaaatca atcggttttt tcttgaacag
     2761 ctctagcgct tccagtccat catgggctac caagacctga taacctgcct gaattaagta
     2821 tctctgatga atatctgtga tttctacctc gtcgtcaacg agtaaaattg tctttcccat
     2881 ctgtctctcc tttgataaaa acagtgctat actgctttaa gtataacact atttttattg
     2941 ttttacgatg attttaatct gctattgaaa gaaagtcctg attgctgatt gagttgttaa
     3001 actaatctta gtcagcccac tatccatcat ttatttcctt agctgattag ttttcttctt
     3061 ttttgttttt caaacctaga ccaccgagta aacctgcaag cgcaagccca agtaaaccaa
     3121 tacttgccat tgatgtttga gtctcaccag tatttggtag catagcttta tcctctgaca
     3181 tcatcgtatc agacatcttg ttagcagaag cagccatgtt ttcacctgcc atcgtgttgg
     3241 tagaacttgt catggtgtca gcaggcatgc tatctgtagt acctgtagca tgattgtgat
     3301 tcatcggagt cacgccagaa ccagagttag aaggtgataa tgaaccattt gctgtgtctg
     3361 atgtttcttt aacatttatc ttaatagtga cttttttagt tgctacgatg ttgtccaagt
     3421 ctggtttacc gtctttgtta ccatagacat tgactgtagc gctgtaagtt tgagtgccgt
     3481 ttgctcggaa ctggtcaatg agcgcttgtt tttctttgcc agctacattt ccgtccaagg
     3541 ctacttgata gaagtattga cctttggtct tcacgttttc gcctagtgga gatagggctg
     3601 ggtttttagc gtc
//
LOCUS       DAVBOH010000091         3572 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOH010000091 DAVBOH010000000
VERSION     DAVBOH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.092"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..127
                     /locus_tag="VQ873_002079"
     CDS             <1..127
                     /locus_tag="VQ873_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3108276.1"
                     /translation="ARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESIK"
     gene            111..560
                     /locus_tag="VQ873_002080"
     CDS             111..560
                     /locus_tag="VQ873_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108277.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            553..933
                     /locus_tag="VQ873_002081"
     CDS             553..933
                     /locus_tag="VQ873_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108278.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            946..1179
                     /locus_tag="VQ873_002082"
     CDS             946..1179
                     /locus_tag="VQ873_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3108279.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            1182..1769
                     /locus_tag="VQ873_002083"
     CDS             1182..1769
                     /locus_tag="VQ873_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3108280.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            1899..2489
                     /locus_tag="VQ873_002084"
     CDS             1899..2489
                     /locus_tag="VQ873_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3108281.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            2489..3325
                     /locus_tag="VQ873_002085"
     CDS             2489..3325
                     /locus_tag="VQ873_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3108282.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
BASE COUNT         1240 a          521 c          653 g         1158 t
ORIGIN      
        1 tgctagaaaa gtctctagta atagtcagct ctataaacaa gctggtaata gtgtaaccgt
       61 tcctgtgatt gccgcaatcg caaagaaatt aaaagaaata gaggaaaaag atgaaagcat
      121 taaataaaga atcaatacta gattgtgatg aattagaaac agaattacat gatgcagaaa
      181 tcaaacagct ggatgaacaa ttatttttga tgcccaatta tccatgtgag tttgaagtaa
      241 catttttaga tgattaccat aaaaaacaca actacccact attttacgag tcctatcttc
      301 aaaacgttat ggaattcctt gaaagtcaag acataaagaa tggggttgat gcctttgtag
      361 atgatcatca aaatctcgtt tttgttttat atggacaagg ctatcgagca gagggaaaag
      421 agggaatact tacaactcaa gtaactgtaa aagcttatga tgaagacaag aaaccgatta
      481 acttcgcaaa tttattagat tccttaatcg tctcagaata tcaaatggaa ccgaatcttt
      541 ggaaggtctc ccatgattga tctctatcta agtaaaaata gccaaagaaa tcaacttctt
      601 ttggatttct ttcaaaagta tggcatagag gtcactcctc attctatttc tgaaatgaca
      661 aaggacaaat taattgaaat gatgagctat tcttcagatt gttttgagtt tctatctccc
      721 aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcat tgaaatgata
      781 ttaaaaaatc ctgaactatg catcaggctt cctcttgcgg tttcaaataa gagagtttat
      841 ccaaatctga atttggaaga ggctagagct ctattgccaa gagatacgaa acaattgatt
      901 tacatggcac aaacacatta tttatctagt taaaggagaa gcaatatggc tgaacgattt
      961 tgggagaact tgtccattat tttggctgaa agaaatatta gctggattga gttaaccaga
     1021 aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta tcaaaagata
     1081 cgccactaca agatggaaca acgaatgcct caaagtccat gggtagaaag gattgtgcag
     1141 gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga ataattccag
     1201 tttatatatt ccaacaagta aatgtcttat tggtatccct atacttactg aaattgcttt
     1261 gtattggtga gttaaccata ctacagattc tctattgtgc gtcgctcatt tcttttttat
     1321 ggatgtatgg tcaacgaaaa caagtggtca aggtcaatat gaaaactagg atgaaatggc
     1381 ttggtattgg attcgttagc ctactgatta taagcctatg ttttagtctg attcatgctc
     1441 aaggaaccac gaatcaagca aacttaattg gccttcaaca tcaggttcct tggttttcat
     1501 ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga gaaattttat
     1561 ggaacttggt cagaaaatta gatattcgag ttgctttgac aagtgtttta tttgccttag
     1621 tacatcatcc aggaaccatt ctagcttggt gtttatatgt ttcacttggg atctttttag
     1681 ggatggtgcg ctataaatcg gacttatggg gaagtatggg tctacatttg gtgtggaacc
     1741 tatcagtcta tgtcttattt tttctttaat aatagctggt ctgtcttacg tatggattaa
     1801 ttttgaaata aaaaaactaa atgaattgat tttaaagaaa taaaatgcta acatatatag
     1861 aagatgttag cattttattt ctaagaaagg agaatggtat ggttgataaa agagagaaac
     1921 tgatgaactc tttcaatcag tatggttttt taacttttaa acaagtaata gatgaaaatt
     1981 tacactacaa aaccttatta aaaatggtta cagaaggaaa aatcgatgct gaagaaaaag
     2041 ggttatatcg cttacctgat atttatttag atgagtggtt tgtcattcag tatcgatttc
     2101 caaaaggaat cttttctttg gagacagcac tttggttaca tggtttatct ttgactatcc
     2161 cttttaacat gacaatgagt tttccttatg gtacgaatac caaaaacatt aaggaagcag
     2221 atatatgtcc tattatctta cgctctcact atagtgaagg aattattgaa atagagcgtc
     2281 ttcctggtca atttattaaa gtttatgaaa ttgaacgagt tttggttgaa tgtctaagac
     2341 cagttcatca ggtggatctt caaattattg caccagcgtt taagaaatat tttcaacaga
     2401 atcaaattca tttacacaaa ttattttatt atgcccaact atttaaagta actgataagt
     2461 tacaatctta tacggaggtg ctatcttaat gttttcaaat gcgaatagct ttaaagcaaa
     2521 aatcaaaaat atttcaaaag ataagggaat tccagctcaa caagtacaac aacattattt
     2581 aattgagcaa gtgttaaagc tgatttctac tagttcttat agagattcct tcattgtaaa
     2641 aggagggtat ctaataggtc aaatgattgg actagataag cgaaccacaa tggatttaga
     2701 tgtcactctg aagggaaccg aaatgagcag agaaaatttg attgatatct ttgaagagat
     2761 tctttgttct aaaactgatg gtttttcatt ttcagtagat aagctagaac ctattcgcca
     2821 agatgatgaa tatggaggat tttcattaaa attaaatgca acttttgata cattaaagga
     2881 ggttgttttt attgatatta ctactggtga taagatcaca ccaagagaaa ttacttattc
     2941 aatgacttct atctttacta atgaaagcat caagatatgg acatataatc tagaaactgt
     3001 acttgctgaa aagttagaaa caatcattag taggggatta gcttcaacac gcccacgtga
     3061 tcgatatgat cttttcacct tgtataaact tagaaaagaa gagattaatc ttgaagtatt
     3121 aaaaaatgca cttgaaaata cagcaaaaaa acgtaaaagt aaagatacta tttataattg
     3181 ggaagaacaa gtgagaggaa ttgaaatttc tgattatcag aaagagctat ggattcgtta
     3241 tcaacgccaa tttaagtatg ctaaagatat ctcatttgat aactctgttc aggttattag
     3301 ggaaattatg caacaaatat tttagtacaa aagtaactca ttcgtaaagc agtgagttgc
     3361 tttttttatt ccaacaacct caaacatgtg ataaaaattt caactactct tatctataat
     3421 aaagctacct gttctttgaa aattgaatcc actccgtctt gattagcgtg cctgtgtaag
     3481 tagggaatga gagtatttcc ctgtgaaggg caactggcac aagacgtgtg tgagaatttt
     3541 ctaacagaca cggagtttat cgtttccaga ct
//
LOCUS       DAVBOH010000092         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOH010000092 DAVBOH010000000
VERSION     DAVBOH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.093"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ873_002086"
     CDS             complement(64..1005)
                     /locus_tag="VQ873_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3108283.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ873_002087"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ873_002087"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3108284.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          846 a          688 c          578 g          797 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtta cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBOH010000093         2853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOH010000093 DAVBOH010000000
VERSION     DAVBOH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.094"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            108..824
                     /locus_tag="VQ873_002088"
     CDS             108..824
                     /locus_tag="VQ873_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3108285.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1133..1558
                     /gene="rplK"
                     /locus_tag="VQ873_002089"
     CDS             1133..1558
                     /gene="rplK"
                     /locus_tag="VQ873_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3108286.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1766..2455
                     /gene="rplA"
                     /locus_tag="VQ873_002090"
     CDS             1766..2455
                     /gene="rplA"
                     /locus_tag="VQ873_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3108287.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          955 a          535 c          642 g          721 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattaaaag attagtcaaa
       61 cgtttatcat cagaagtaga taaactatta gaaataaagg agtagaaatg aagaaaagat
      121 accttgtcgt gacagccttg ctagccttga gtctagcagc ttgttcacaa gaaaaagcaa
      181 aaaatgaaga tggcacagct aagacagaac agacagccaa agctgatggg acagtcggca
      241 gtaagtctca aggggctgcc cagaaaaaag cagaagtggt caataaaggt gattactaca
      301 gcatccaagg aaaatacgac gaaatcatcg tagccaataa acattatcct ttgtcgaaag
      361 actataatcc gggggaaaat ccaacagcca aggctgagtt ggtcaaactc atcaaagcga
      421 tgcaagaggc aggtttccct attagtgatc attacagtgg ttttagaagt tatgaaactc
      481 agaccaagct ctatcaagat tatgtcaacc aagatggaaa ggcagcagct gaccgttact
      541 ctgcccgtcc tggctatagc gaacaccaga caggcttggc ctttgatgtg attgggactg
      601 atggtgattt ggtgacagaa gaaaaagcag cccaatggct cttggatcat gcagctgatt
      661 atggctttgt tgtccgttat ctcaaaggca aggaaaagga aacaggctat atggctgagg
      721 aatggcacct gcgttatgta ggaaaagaag ctaaagaaat tgctgcaagt ggtctcagtt
      781 tggaagaata ctatggcttt gaaggcggag actacgtcga ttaatactct tcgaaaatct
      841 cttcaaacca cgtcagcgtc gccttaccta ctgactgcgt cggttctatt cacaacctca
      901 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa tctcaaagct gtactttgag
      961 cagcctacag ctagcttcct agtttgctct ttgattttca ttgagtataa aaaataaact
     1021 tttctcttgc aattccagat aaatagtgta taatggatgg gtatgtgaaa aacatacttg
     1081 tgggaggtaa aaatctctaa ttaccgccaa aaccacaaag gaggatttaa aaatggctaa
     1141 aaaagtcgaa aaacttgtaa aattgcaaat ccctgctggt aaagctacac cagctccacc
     1201 ggttggacct gctcttggtc aagctggtat caacatcatg ggattcacaa aagagttcaa
     1261 cgctcgtaca gctgaccaag ctggtatgat cattccagtt gttatctcag tttacgaaga
     1321 taaatcattt actttcgtta cgaaaacacc accagctgct gttcttttga aaaaagctgc
     1381 aggtgttgaa aaaggatcag gtacacctaa taaaactaaa gttgctacag ttactcgtgc
     1441 acaagtacaa gaaattgcag aaactaagat gccagatttg aacgcagcaa acgtagagtc
     1501 tgcaatgcgt atgatcgaag gtactgctcg ttctatggga ttcactgttg ttgactaatc
     1561 aataacacag tagaaaatct cacagcagtc tattagttgc ttttcatact aggcaagtga
     1621 ctgaggcttg tacttgggta cagcaaggga gcttaaggcc gtaggaagag aaaaatagta
     1681 gactgaaaac ccgcaagact tcatcatttc gagaagtgac gtgggagatg aaaatcgatt
     1741 gaaccactta caaggagaat agaaaatggc taaaaaaagc aaacaacttc gtgctgctct
     1801 tgagaaaatc gacagcacaa aagcatacag cgtagaagaa gctgtagcac ttgcaaaaga
     1861 aactaacttt gcaaaatttg acgcaactgt agaagttgct tacaacttga acatcgacgt
     1921 taaaaaagct gaccaacaaa tccgtggagc aatggtattg ccaaacggta ctggtaaaac
     1981 ttcacgtgtt cttgttttcg cacgtggtgc aaaagctgaa gaagcaaaag ctgctggtgc
     2041 agactttgtt ggtgaagatg accttgttgc taaaatcaac gacggttggt tggatttcga
     2101 cgtagttatc gctacacctg atatgatggc tcttgttgga cgtcttggac gtgtccttgg
     2161 accacgtaac ttgatgccaa accctaaaac tggtactgta acaatggatg ttgctaaagc
     2221 agttgaagag tctaaaggtg gtaaaatcac ttaccgtgct gaccgtgcag gtaacgttca
     2281 agcaatcatc ggtaaagtat catttgaagc tgaaaaattg gttgaaaact ttaaagcttt
     2341 caacgaaaca atccaaaaag caaaaccagc tacagctaaa ggaacttacg taacaaactt
     2401 gactatcaca actactcaag gtgttggtat caaagttgac gtaaactcac tttaatcagt
     2461 agttaaagta atgtaaaaaa gttgaagacg ctatgtctca actttttttg atatacgacg
     2521 ggcatgtcgt atatctgagg tgtaaatcct cggtgggcac ctactactgg tgaacccaat
     2581 agcgattccc aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg
     2641 ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa atcgtggctc
     2701 tacgaacagg aacgtgataa taaggcctat atagcggata aggtatctgg ctggggcgac
     2761 cactatcaat tatagtaaaa tgaaataaga gtaggacgaa tcgatcaggg cagccaaatc
     2821 gatttctaac aatgttttag aagaagagat gta
//
LOCUS       DAVBOH010000094         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOH010000094 DAVBOH010000000
VERSION     DAVBOH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.095"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ873_002091"
     CDS             448..2553
                     /locus_tag="VQ873_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3108288.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBOH010000095         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOH010000095 DAVBOH010000000
VERSION     DAVBOH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.096"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ873_002092"
     CDS             complement(173..838)
                     /locus_tag="VQ873_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3108289.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ873_002093"
     CDS             complement(852..2231)
                     /locus_tag="VQ873_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3108290.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBOH010000096         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOH010000096 DAVBOH010000000
VERSION     DAVBOH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.097"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ873_002094"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ873_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3108291.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ873_002095"
     CDS             1681..>2364
                     /locus_tag="VQ873_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3108292.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          832 a          430 c          475 g          627 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgattct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOH010000097         2270 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOH010000097 DAVBOH010000000
VERSION     DAVBOH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.098"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            70..608
                     /locus_tag="VQ873_002096"
                     /pseudo
     CDS             70..608
                     /locus_tag="VQ873_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="VQ873_002097"
     CDS             675..1085
                     /locus_tag="VQ873_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3108293.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..>2270
                     /gene="pavB"
                     /locus_tag="VQ873_002098"
     CDS             1201..>2270
                     /gene="pavB"
                     /locus_tag="VQ873_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3108294.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKAS"
BASE COUNT          688 a          441 c          509 g          632 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag tcccctaaag
       61 gagcagatta tgaagttatt gtctatcgcc atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggatcagac tcagaaatcg ctgagtgttt agctagcaag tatcctaata
      241 tcgttagagc catctatcag gaaaataaag gccatggcgg tgcggtcaat cgtggcttgg
      301 cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa gaggtggatg
      421 tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccaa cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaaca
     2101 gttcaaaaag ccgttgcaga taacgttaag gacagtatcg atgttccagc agcctaccta
     2161 gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatatgaa
     2221 ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatctga
//
LOCUS       DAVBOH010000098         1863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOH010000098 DAVBOH010000000
VERSION     DAVBOH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.099"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..917)
                     /locus_tag="VQ873_002099"
     CDS             complement(<1..917)
                     /locus_tag="VQ873_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3108295.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCL"
     gene            complement(1362..1760)
                     /locus_tag="VQ873_002100"
     CDS             complement(1362..1760)
                     /locus_tag="VQ873_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3108296.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          502 a          380 c          325 g          656 t
ORIGIN      
        1 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
       61 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
      121 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
      181 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
      241 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
      301 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
      361 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
      421 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctggcctg tttcttaagc
      481 gcttttcctt ttctagggta aggcaaatcc tgcttgctta accccaattt tccatgatga
      541 atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac catcatttca
      601 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcaagctt
      661 gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcgta gtcggcagaa
      721 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
      781 gtgtggatag tttgaggagc ttttccaagt agagaggcaa cttctctatt tgattttcct
      841 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt accttttgta
      901 gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
      961 acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct tttggatttc
     1021 actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac ctgtaaattt
     1081 aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga gagtttttag
     1141 tttaaataaa ttgtttaaaa tatcaacaac atcacttctt ttcttaacct gataagtctt
     1201 gattcctaat tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt
     1261 tctaggttat aactggtatt tatcgatagt tactcatata catcagtcca cctccatact
     1321 tatgtgcgag cctctctttg tattatacct ccatactcac cttacagatt cttttggtaa
     1381 taatatcttt gcctaatgta gagatagtct tgcaaagaaa aaacttcctt gtagccatgt
     1441 ttctgataaa agtccggtgc ctggaactgg taagtattga caaaggcaaa acaacaattt
     1501 cgattcttag cttcactttc tgcctgttgc aatagttttg aaccgattcc ttgccctcgc
     1561 agttcctctt ttacaaacaa atactcgatt tctagccaat ttccaaaagt ctctgctatc
     1621 aaacctgcca ggagattgcc cttttcatct tcgacataaa gattaagtgg ctcactttca
     1681 gcctcttctc tttttgaacg gttataaaca cgaatcagat tccctatttc ttgcgattta
     1741 tgtgattcct tattttccaa tctaatgaaa tgaaataaaa catgcgcaaa tcgattaagg
     1801 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
     1861 cac
//
LOCUS       DAVBOH010000099         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOH010000099 DAVBOH010000000
VERSION     DAVBOH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.100"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ873_002101"
     CDS             complement(3..968)
                     /locus_tag="VQ873_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3108297.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ873_002102"
     CDS             complement(1086..1499)
                     /locus_tag="VQ873_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3108298.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ873_002103"
     CDS             complement(1496..1732)
                     /locus_tag="VQ873_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3108299.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOH010000100         1853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOH010000100 DAVBOH010000000
VERSION     DAVBOH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.101"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..606)
                     /locus_tag="VQ873_002104"
                     /pseudo
     CDS             complement(1..606)
                     /locus_tag="VQ873_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            848..1188
                     /gene="tnpB"
                     /locus_tag="VQ873_002105"
                     /pseudo
     CDS             848..1188
                     /gene="tnpB"
                     /locus_tag="VQ873_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1221..1853)
                     /locus_tag="VQ873_002106"
                     /pseudo
     CDS             complement(1221..1853)
                     /locus_tag="VQ873_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          539 a          363 c          312 g          639 t
ORIGIN      
        1 aatccgacga taaccataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg ttttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaatatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tttccgctct caggtactct ccctcttgtt ttctcaacaa tagtataccc
      301 gtttttcctg tattgtgcta gccagttaag aagtatcgta cgacttggga gacagtattc
      361 aagagaaact ctatctttag tccagccttc atgtcagact ttattaatca tttcttgttt
      421 taaatcagga gaatagtaac gattttttcc ttttttgacg aactctattc cgtaacgatc
      481 aatcaattta atcatatacc taagattaga attgtttatc ccaaatttat ttgaaagctt
      541 ctctaagcta tatccttgtt ttctaagttc atagatctga actttatcat cataactcaa
      601 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggggcagtt
      661 cattctacac ccactattat gcgtttttat cattttgaaa tctactgcta atcaatgaag
      721 aagcaaagat caaactaggc agctagttac aagttacgta agcgcgtcat aacaaggtat
      781 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
      841 ttgtactatg ataattcaac taagtgattt aggtcaagtt caccttgttt gtagcaagat
      901 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
      961 tcctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct ttaaagccct
     1021 ttactgggat ggtcaaggat tttggctact atataaacgc tttgagaacg gcagactgac
     1081 ttggcccagt acagaaaagg atgtcaaagc tctcacacct gaacaagtag actggcttat
     1141 gaagggcttt tctatcactc caaaaataaa tccatcagaa agtcgtgatt tctattgaaa
     1201 tgaggacttt ctttttatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta
     1261 acgatgggct ttatcacctc cttctccagt ccttgtatga tatcttaaag ttgattcatg
     1321 acatcttcca aagtttgaaa ggctttattt ttaaatccac gtttacgaat ctctttccac
     1381 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa gccaatatta
     1441 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gaataaaaga
     1501 taatcatctg gataagcttg tgaaagctct tctaaaaaga cgttcatcca ctcagtatta
     1561 catccaccag ctattaagaa aaatgattcg cctgtatggg tccataacaa tagcgaaatt
     1621 ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa caagatccca
     1681 gtttactgat tctaccgaag ccagcctcat cttggtacat caagcgaacc ttatgaaaac
     1741 gtctactggt tttaaagcgc tttcttttct tcttgaattg aaattttatt tttagacgcg
     1801 acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcataat att
//
LOCUS       DAVBOH010000101         1803 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOH010000101 DAVBOH010000000
VERSION     DAVBOH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.102"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(101..642)
                     /locus_tag="VQ873_002107"
                     /pseudo
     CDS             complement(101..642)
                     /locus_tag="VQ873_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(718..1494)
                     /locus_tag="VQ873_002108"
                     /pseudo
     CDS             complement(718..1494)
                     /locus_tag="VQ873_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1612)
                     /locus_tag="VQ873_002109"
     CDS             complement(1418..1612)
                     /locus_tag="VQ873_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3108300.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
BASE COUNT          509 a          381 c          331 g          582 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatat
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttta aaatggtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa
      481 ggcaaataac tggtcacgat aggctaaacc tttagctcct aaggatgatt tatctgcttg
      541 cttgggggtc gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc
      601 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      661 gctcctaaac cttagactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
      721 ctgccgcaac atatcacaat gcatatagcc agaataattt cctaggaatt cttgcactac
      781 cgaaccactc cgacgctgat catggtggta cagcgtaatc ccttgtttct cagctttccc
      841 agacaaaaaa gtccaatagt aagtcagctg actatcactt tctaagaccc gataagaggt
      901 ttcatctgca tgaagaagag cttgttctaa caacttttct cgtaaaaggt tataaaggga
      961 ctctaaatag tattgactcg ccttgatatg ccaattagca atttccttac gtgtgattgg
     1021 taaacccatc ttagcccaat cttcttctta gcgataattg ggtaccttca gaataaactt
     1081 ctgatggatg gtgtgagcga taatagaagc tgagccaagg ctatgcgcca aaggggcttt
     1141 aggaatagga gctttcacga ttttatcact tggattattc ttactgcatg tttggcattt
     1201 gtaagcgtgt tggatatgat tcactctttt taattgcgca agaataaaga ccaattcttg
     1261 tcgttgaagg ctcgctccaa tctcttttag ctctccctga cagtcagggc aaatgcagtt
     1321 ctctaagcga tgatgaactt cttctgaatc aaattgggca agaatagctt gacgtttccc
     1381 tttagctttc ttacgtttat aggtgatttc ttctctttca actgggtaag tcagagtctt
     1441 cttccatatt ttgttcctct tcaaaaagac tgagttgtcc agatgggcaa acacttttct
     1501 cagaggattt tccatagagc ttttgcgtta gataagccac ttgttcacga agaagggcaa
     1561 gttcattggt gagactatca attgtagcac tctgttgttg aatgattttc aatcttctcc
     1621 catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc tataacagta
     1681 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcat
     1741 atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa atcacgactt
     1801 tct
//
LOCUS       DAVBOH010000102         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOH010000102 DAVBOH010000000
VERSION     DAVBOH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.103"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ873_002110"
     CDS             complement(242..1006)
                     /locus_tag="VQ873_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3108301.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ873_002111"
     CDS             1228..1524
                     /locus_tag="VQ873_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3108302.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOH010000103         1555 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOH010000103 DAVBOH010000000
VERSION     DAVBOH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.104"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ873_002112"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ873_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1555)
                     /locus_tag="VQ873_002113"
     CDS             complement(1202..>1555)
                     /locus_tag="VQ873_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET3108303.1"
                     /translation="KPNEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEES
                     PEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDNNTI
                     MAEAEKLLALLKESK"
BASE COUNT          469 a          312 c          222 g          552 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggttt
//
LOCUS       DAVBOH010000104         1455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOH010000104 DAVBOH010000000
VERSION     DAVBOH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.105"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ873_002114"
     CDS             <1..559
                     /locus_tag="VQ873_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3108304.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ873_002115"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ873_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3108305.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          504 a          208 c          266 g          477 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAVBOH010000105         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOH010000105 DAVBOH010000000
VERSION     DAVBOH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.106"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ873_002116"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ873_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3108306.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBOH010000106         1056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOH010000106 DAVBOH010000000
VERSION     DAVBOH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.107"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            97..504
                     /locus_tag="VQ873_002117"
     CDS             97..504
                     /locus_tag="VQ873_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3108307.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            669..968
                     /locus_tag="VQ873_002118"
     CDS             669..968
                     /locus_tag="VQ873_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3108308.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          371 a          211 c          184 g          290 t
ORIGIN      
        1 tttggttcat ttcactataa taataacgat actagataat gaggaaaatg caatggcaaa
       61 cccaactttc ggagaaaaaa agcgaataca gactatattg ctcgctatgg cgtatatgca
      121 gttatcccta atcctgaaca aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg
      181 ttcctaccat gtggagaaat tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag
      241 ttgattgaag agcttggttt cacagcagaa attggtacct attacggaca agctgacgaa
      301 tatttctatt ctcgtcatcg tgatacctac tactacaatc ctgcctacct ctatgaagca
      361 acttctttca aagaagtaca aaagccacta gaaaacttta atcatattgc ctggttccct
      421 attgacgagg ctatccaaaa ccttaaacgt ggtagccata aatgggccat tgaatcttgg
      481 aaaaaacagc ataagattga ctaatactct tcgaaaataa aatttaaacc acgtcagcgt
      541 cgccttaccg tactcaagta tagcctgcgg ctagcttcct agtttgctct ttgattttca
      601 ttgagtataa atcaagcgac tttattcaaa aagtgctata atagaattag aaaatcggag
      661 gaaatattat gaagcttatc aatacgacaa actcacactc gcaacttgta aaaagtcagc
      721 tagaaagtac cgatgcaacc cttgttgagg tttattctgc agggaataca gatgttattt
      781 ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg
      841 agcctgaaat cgaaaccatt caagaatttt tcttgaaacg taaaattgat aagacctctg
      901 ttgatgaagc caatatcaag acactctact cagagaaatt aattggaatt tcaatcccaa
      961 tcaagtaaga aaattgagta aaaactcgat ttgagagaaa gtccaataag tctttccata
     1021 ataaaacgca tagtagcagg tgccgaaatg aactgc
//
LOCUS       DAVBOH010000107         1044 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOH010000107 DAVBOH010000000
VERSION     DAVBOH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.108"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VQ873_002119"
     CDS             <1..550
                     /locus_tag="VQ873_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3108309.1"
                     /translation="ETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..1043)
                     /locus_tag="VQ873_002120"
     CDS             complement(498..1043)
                     /locus_tag="VQ873_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3108310.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          375 a          167 c          149 g          353 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgctcagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagaaga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgttc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt
     1021 atttttataa caacccaatt cata
//
LOCUS       DAVBOH010000108         1000 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOH010000108 DAVBOH010000000
VERSION     DAVBOH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.109"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..105
                     /locus_tag="VQ873_002121"
     CDS             <1..105
                     /locus_tag="VQ873_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3108311.1"
                     /translation="IEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(402..689)
                     /locus_tag="VQ873_002122"
                     /pseudo
     CDS             complement(402..689)
                     /locus_tag="VQ873_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            688..951
                     /locus_tag="VQ873_002123"
                     /pseudo
     CDS             688..951
                     /locus_tag="VQ873_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          368 a          155 c          175 g          302 t
ORIGIN      
        1 attgaattta aacgtgttgg tatctttgat gggaaagcag tagaagttac tcttcgagaa
       61 ccttattcga gagatctact gcaggttgtc aagtcaataa agtaactgac accacgagta
      121 taattattag aaacgtggaa tcttattaaa ttttataata aatatattaa atgaaaaatt
      181 attagatata aacttatgta ataaaacatt gaggaaataa taaaaatcta tgggtaatgt
      241 tctgaaagta cttttaggtt aggagagaaa tataatgatt tttgaaaatt gattcaaaaa
      301 atagcgaatt gtagaaaacg cttaacaaat ggtgtataat agacttccag cgaaacaaaa
      361 tatgctacaa taaacctatg aattataaag taaccttata ctcatctgtc ttcacaaagc
      421 attctagtcc atctccgatt aacgatggac tttatcatct ccttctccag tccttgtatg
      481 acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac
      541 acttattcaa tggggttcat ttctggtgtg tatggaggaa taaatgcaaa gccaatatta
      601 gtcggaatct ttaaggcact tgatttatgc catatagcat tgtccataac gaataaaaga
      661 taatcatctg gataagcttg tgaaagcttg gctgacagtg gttatcaagg gctcatgaag
      721 atatatcttc aagcacaaac tccacgtaaa tccagcaaac tcaagccgct aacagctgaa
      781 gataaagcct ataaccatgc gctatctaag gagagaagca aggttgagaa tatttttgcc
      841 aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa acgcttcgga
      901 ttacgaatga atttgattgc tgatattatc aatcatgaac taggattcta gttttgcagg
      961 aagtctaata aatgtataag aaaaaggagg aaaaaggatg
//
LOCUS       DAVBOH010000109          765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOH010000109 DAVBOH010000000
VERSION     DAVBOH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.110"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ873_002124"
     tRNA            complement(74..147)
                     /locus_tag="VQ873_002124"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ873_002125"
     tRNA            complement(157..242)
                     /locus_tag="VQ873_002125"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ873_002126"
     tRNA            complement(250..321)
                     /locus_tag="VQ873_002126"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ873_002127"
     tRNA            complement(344..416)
                     /locus_tag="VQ873_002127"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ873_002128"
     tRNA            complement(435..516)
                     /locus_tag="VQ873_002128"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ873_002129"
     tRNA            complement(522..594)
                     /locus_tag="VQ873_002129"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ873_002130"
     tRNA            complement(619..691)
                     /locus_tag="VQ873_002130"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..765)
                     /locus_tag="VQ873_002131"
     tRNA            complement(694..765)
                     /locus_tag="VQ873_002131"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          195 a          225 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcc
//
LOCUS       DAVBOH010000110          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOH010000110 DAVBOH010000000
VERSION     DAVBOH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.111"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ873_002132"
     CDS             <1..>758
                     /locus_tag="VQ873_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3108312.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOH010000111          746 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOH010000111 DAVBOH010000000
VERSION     DAVBOH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.112"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ873_002133"
     CDS             3..305
                     /locus_tag="VQ873_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3108313.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..746
                     /locus_tag="VQ873_002134"
                     /pseudo
     CDS             313..746
                     /locus_tag="VQ873_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          246 a          138 c          153 g          209 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aagtctcaag cgattg
//
LOCUS       DAVBOH010000112          641 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOH010000112 DAVBOH010000000
VERSION     DAVBOH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.113"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..>641
                     /locus_tag="VQ873_002135"
     CDS             <1..>641
                     /locus_tag="VQ873_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET3108314.1"
                     /translation="ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD
                     LIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRR
                     VCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFF"
BASE COUNT          177 a          147 c          128 g          189 t
ORIGIN      
        1 tgaattggtc gaattctttt tacagtttca ccagctaaac caactcattg tagatatcga
       61 ttctacccat ttcacaactt atggcaagca agaaggtgtt gcttataacg cccactatcg
      121 tgctcatggc tatcatcctc tttatgcttt cgaggggaag acaggttatt gtttcaatgc
      181 ccagcttcgt cctggtaatc gttattgttc tgaagaggca gacagcttta tcacacctgt
      241 tttagaacgg tttaatcaac ttctctttcg aatggatagt ggctttgcga ccccaaaatt
      301 atacgattta attgaaaaaa cagggcaata ctacctcata aaactcaaga aaaatactgt
      361 tctgagccgt cttggagacc tttccctccc ttgcccacag gatgaggact taaccatctt
      421 gccccactcc gcctactcag aaactctcta tcaagcagga tcttggtcgc acaagcgtcg
      481 tgtctgccag ttctctgaac gaaaagaagg aaacttgttc tacgatgtta tttctctcgt
      541 tacaaatatg acgagtggaa caagccaaga ccagtttcag ctttatcgtg gacgtggtca
      601 agccgagaat ttcatcaagg agatgaagga gggatttttt g
//
LOCUS       DAVBOH010000113          630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOH010000113 DAVBOH010000000
VERSION     DAVBOH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.114"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ873_002136"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ873_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          228 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta
//
LOCUS       DAVBOH010000114          608 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOH010000114 DAVBOH010000000
VERSION     DAVBOH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.115"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..>608
                     /locus_tag="VQ873_002137"
     CDS             <1..>608
                     /locus_tag="VQ873_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3108315.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAP
                     KGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT          200 a          126 c          135 g          147 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag gtttgacccc tccttcgaca gaccatcagg attcaggaaa tactgaggca
      301 aaaggagcag aagctatcta caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt
      361 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
      421 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      481 aaggggtata gtcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      541 gaacgtccgc attcagataa tggttttggt aacgctagcg accatgttca aagaaacaaa
      601 aatggtca
//
LOCUS       DAVBOH010000115          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOH010000115 DAVBOH010000000
VERSION     DAVBOH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.116"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ873_002138"
     CDS             <1..>601
                     /locus_tag="VQ873_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3108316.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBOH010000116          598 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOH010000116 DAVBOH010000000
VERSION     DAVBOH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.117"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..555
                     /locus_tag="VQ873_002139"
                     /pseudo
     CDS             1..555
                     /locus_tag="VQ873_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          206 a          103 c          115 g          174 t
ORIGIN      
        1 aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt actgacaatc
       61 cagacgctta tttgactgaa atagcttctg actttggctg tcatccaact accatccact
      121 atgcgctcaa agctatgggc tacactcgaa aaaagaacca cacctactat gaacaagacc
      181 cagaaaaagt agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt
      241 agattgacga aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag
      301 gtcagttaag aagaggcaaa gtatctggaa gaagatatca gagaatttct ttggttgcag
      361 gtctaacaaa tgaatggtga gttaatcgct ccaatgactt acgaagagac gatgacgagc
      421 gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac accatcggtt
      481 attattatgg ataatgcaag attccataga atgggtaagt tagaactttt atgcgaggag
      541 tttgggtata aactttggct ctataatatt tgtagtgggt aaatccacta tagatatt
//
LOCUS       DAVBOH010000117          585 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOH010000117 DAVBOH010000000
VERSION     DAVBOH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.118"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ873_002140"
     CDS             complement(21..500)
                     /locus_tag="VQ873_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3108317.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          152 a          136 c           76 g          221 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaa
//
LOCUS       DAVBOH010000118          578 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOH010000118 DAVBOH010000000
VERSION     DAVBOH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.119"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..196)
                     /locus_tag="VQ873_002141"
     CDS             complement(<1..196)
                     /locus_tag="VQ873_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3108318.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKYAKGG
                     RKPKLSLEDLLMATLQYVREY"
     gene            191..445
                     /locus_tag="VQ873_002142"
     CDS             191..445
                     /locus_tag="VQ873_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3108319.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT          186 a           85 c          114 g          193 t
ORIGIN      
        1 gatattctcg cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt
       61 ttcgtccacc ttttgcgtat ttaagttgat aagctgtttt taatacagct aatatctctt
      121 caaaagtcgt gcgctgaaca ccaacaagac gcttaaatcg tgcatcagtt agttgtttac
      181 ttgcttcata attcatagaa ctactatacc atattttgtt tcgcaggaag tctattggaa
      241 agtaagaaat attggagctg aggcgattag aagaaattgt gagcgtggtg ctattttttc
      301 aggtaaaata aaacatcacg aagattctca gtttaaagga gagcactatg ttgaatgtta
      361 tgctgtttta gataatacgg ttatagcaag agatagaata acagtcccta tcgatccgtt
      421 atgtggaaaa gattttatag agtagcatat aattgattct taactggaat actctctatc
      481 tctttacatc aagaaaatga ctaaacaggg aagtttgcct tcttcccttt ttttgttata
      541 ctagtagaag aaaaaaatag aaagatttgt gggagtga
//
LOCUS       DAVBOH010000119          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOH010000119 DAVBOH010000000
VERSION     DAVBOH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.120"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ873_002143"
     CDS             complement(<1..534)
                     /locus_tag="VQ873_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3108320.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOH010000120          506 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOH010000120 DAVBOH010000000
VERSION     DAVBOH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.121"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..153)
                     /locus_tag="VQ873_002144"
     CDS             complement(<1..153)
                     /locus_tag="VQ873_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3108321.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQILRNTIYGWLKLKEK
                     TGELNHQ"
     gene            complement(261..334)
                     /locus_tag="VQ873_002145"
     tRNA            complement(261..334)
                     /locus_tag="VQ873_002145"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(298..300),aa:Asn,seq:gtt)
     gene            complement(340..455)
                     /gene="rrf"
                     /locus_tag="VQ873_002146"
     rRNA            complement(340..455)
                     /gene="rrf"
                     /locus_tag="VQ873_002146"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          153 a          111 c           84 g          158 t
ORIGIN      
        1 ttggtggttt agctctcccg ttttctcttt tagctttaac cagccataaa tggtattacg
       61 taagatttgg aaaacgtgtg acgcttctgt tatactacct gttcgctcac aataagagag
      121 aactttttta cgaaaatcta ttgaatatgc cataaaaaga ttataccaca ttgtgtacta
      181 tttttggttc attttactat aacacgaaat agattattat tacataacaa aaaagaggtc
      241 taaacctctt aactcaatta ctccgccagt aggactcgaa cctacgacat catgattaac
      301 agtcatgcgc tactaccaac tgagctatgg cggattaaag ctaagcgact tccctatctc
      361 acagggggca acccccaact acttccggcg ttctagggct taacttctgt gttcggtatg
      421 ggtacaggtg tatctcctag gctatcgtca cttaactctg agtaatacct actcaaaatt
      481 gaatatctat tcaattcaag aaaacc
//
LOCUS       DAVBOH010000121          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOH010000121 DAVBOH010000000
VERSION     DAVBOH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.122"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ873_002147"
     CDS             <1..>501
                     /locus_tag="VQ873_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3108322.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOH010000122          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOH010000122 DAVBOH010000000
VERSION     DAVBOH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.123"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ873_002148"
     CDS             complement(91..228)
                     /locus_tag="VQ873_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3108323.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ873_002149"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ873_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOH010000123          464 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOH010000123 DAVBOH010000000
VERSION     DAVBOH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.124"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            75..>464
                     /locus_tag="VQ873_002150"
     CDS             75..>464
                     /locus_tag="VQ873_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3108324.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDF"
BASE COUNT          157 a           71 c           88 g          148 t
ORIGIN      
        1 agaaagtaat tgacaacggt ttcatatagt gttatactta tggcataaag ttaatggaaa
       61 gaagggaaaa acttatggta ttagattatt tctttgacaa aaaccttgtg ttttgcttag
      121 aagcggataa tcaagaacat ctctttgatc aggttgcaac tttattggaa gaacgagaaa
      181 ttgtaactcc aacttatcgt gaagccttga tcacgcgtga aaagtcattt ccaactggtt
      241 tagatatgga atttctagga aagaacttgc caaatgtagc gattcctcac acagatattg
      301 ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta acttttcaca
      361 atatgatagc tcctgataag gaagtagaag tatccctact cttctttatt attaacaatt
      421 caagttcaag tcaaacaaat attctggctc agttgatgga cttt
//
LOCUS       DAVBOH010000124          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBOH010000124 DAVBOH010000000
VERSION     DAVBOH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.125"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ873_002151"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ873_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOH010000125          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBOH010000125 DAVBOH010000000
VERSION     DAVBOH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.126"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ873_002152"
     CDS             116..>297
                     /locus_tag="VQ873_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3108325.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOH010000126          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBOH010000126 DAVBOH010000000
VERSION     DAVBOH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.127"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBOH010000127          263 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBOH010000127 DAVBOH010000000
VERSION     DAVBOH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.denovo.128"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ873_002153"
     tRNA            1..73
                     /locus_tag="VQ873_002153"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ873_002154"
     tRNA            87..160
                     /locus_tag="VQ873_002154"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ873_002155"
     tRNA            171..260
                     /locus_tag="VQ873_002155"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
BASE COUNT           53 a           66 c           76 g           68 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct ttt
//
LOCUS       DAVBOH010000128         8233 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 353-05
            SAMEA1012565-rid20172613.guided.071, whole genome shotgun sequence.
ACCESSION   DAVBOH010000128 DAVBOH010000000
VERSION     DAVBOH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012565
            Sequence Read Archive: ERR046724
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979943.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979943.1
            Genome Coverage       :: 300x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:41:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,164
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 1,984
            CDSs (with protein)               :: 1,984
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 82 of 136
            Pseudo Genes (incomplete)         :: 56 of 136
            Pseudo Genes (internal stop)      :: 34 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012565-rid20172613.guided.071"
                     /strain="NIG 353-05"
                     /db_xref="taxon:1313"
     gene            <1..2002
                     /locus_tag="VQ873_002156"
     CDS             <1..2002
                     /locus_tag="VQ873_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3108326.1"
                     /translation="SRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNFI
                     WTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLLL
                     LILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDIS
                     NASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRVE
                     SLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFVF
                     LLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLIIT
                     TAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVM
                     RKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKE
                     KSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDL
                     TSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYH
                     DEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTA
                     DRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            1999..3000
                     /locus_tag="VQ873_002157"
     CDS             1999..3000
                     /locus_tag="VQ873_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3108327.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2997..3932
                     /locus_tag="VQ873_002158"
     CDS             2997..3932
                     /locus_tag="VQ873_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3108328.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            4177..4293
                     /locus_tag="VQ873_002159"
     CDS             4177..4293
                     /locus_tag="VQ873_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3108329.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ873_002160"
     CDS             4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ873_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3108330.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6347..6514
                     /locus_tag="VQ873_002161"
     CDS             6347..6514
                     /locus_tag="VQ873_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3108331.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(6574..6927)
                     /locus_tag="VQ873_002162"
     CDS             complement(6574..6927)
                     /locus_tag="VQ873_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3108332.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            7432..7854
                     /locus_tag="VQ873_002163"
     CDS             7432..7854
                     /locus_tag="VQ873_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3108333.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            7851..8081
                     /locus_tag="VQ873_002164"
     CDS             7851..8081
                     /locus_tag="VQ873_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3108334.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
BASE COUNT         2689 a         1471 c         1667 g         2406 t
ORIGIN      
        1 cagccgatac ccacttgaaa actatcaact ggatttttat gtggataata gctggggctg
       61 gcttccgtgg aactggtcgg acgggattgg aaaacaggtc atgtatggac tatatgccat
      121 taccaatttt atttggacaa tcagtttgta tgtttccaat gcgacaggtt acttagtaca
      181 ggaagcctat tccttagact tcatttccgc tacagcagat tccattggta agaatatgca
      241 gaccttagct ggtgtgagtg caaacggatt ttcaacagag ggtttctatg ttggattcct
      301 cttactcttg attttggttc ttggggttta tgttgcctat acgggactga taaagagaga
      361 aaccacaaag gcaattcatg ccattatgaa ttttgtgctg gtgtttatcc tatcggcttc
      421 ctttattgcc tacgctcccg actacattaa aaaaatcaat gacttttcat cagacatcag
      481 taatgccagt ttatcacttg gcacgaagat tgtcatgccc cattccgata gtcaaggcaa
      541 ggacagcgtg gacttaatca gagatagcct gttttccata caggttcagc aaccgtggct
      601 actgcttcaa tacaacagtt cagacattga aagtatcggt attgaccgtg tggaaagcct
      661 gctctccacc agcccagatt ccaacaatgg cgaagacaga gaaaaaattg ttgcggaaga
      721 aattgaagac agaagcaata ccaatctaac cattacaaag accattaacc gtttaggtac
      781 agtcttcttc ctatttgtct tcaatattgg gatttccata tttgtattcc tattaacagg
      841 aatcatgatt ttctcgcagg tactttttat catctatgct atgtttctgc ctgtgagctt
      901 tattttaagc atgattccat catttgatgg tatgtcaaaa cgagccataa caaagctctt
      961 taataccatt ttgacacgag ctggaatcac attgattatt acgacagcat ttagtatttc
     1021 aaccatgctc tataccttat cggctggtta tccgttcttt ttgattgctt ttctacagat
     1081 tgtgaccttt gcaggaatct acttcaagct gggcgattta atgagtatgt tttctctaca
     1141 gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga aaacctcgta tgcttatgca
     1201 cgctcacatg caccgtctac agcggaaact tggacgttcc atgactactc taggggctgg
     1261 gtctgccatt gttacaggta aaaaaggaca gtcgggttcg gggagttctg caaggacaca
     1321 agcagatcac tcccgaccag acggaaagga aaaatcaaca cttggaaaac gtatcggtca
     1381 aaccatcggt acagtagctg ataccaaaga cagaatggta gacactgcta gtggtttgaa
     1441 agaacaggtt aaagatttgc cgaccaatgc aagatatgca gtatatcaag gaaaatccaa
     1501 agtaaaagag aatgtccgtg atttaaccag tagtatttct caaaccaaag cggacagagc
     1561 cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc attgcgaagc gtcgctctga
     1621 aatggaacag gtcaaacaga aaaaacagcc tgcttcttct gttcatgaaa gaccgactac
     1681 aagacaagaa caatatcatg atgaacagac ctcaaaacag tctaatattc agacttcata
     1741 taaggaatct caacaagcca aacaagagcg tccagcagtt aagtccgatt tttcaagtcc
     1801 aaaagtggaa cgccaaggca ataccgttca agaaaaaacc gttcaaaagc cagcaacttc
     1861 aaccactaca gcagatagaa cttcacaacg tccaatcaca aaagaacgtc cgtctactgt
     1921 tcaaagagta ccactacaaa atacaagaag tagaccacca atcaaaaccg ccaccattaa
     1981 gaaagtcggt aagaaaccat gaagttgaaa actttagtga ttggtggttc tggattattc
     2041 ttgatggtct tctcactgct tctgtttgtt gccattttat tttcagatga acaggacagc
     2101 ggaatttcca atattcatta tggaggtgtg aatgtttccg cagaagtgct ggctcataag
     2161 cctatggtag aaaaatatgc caaagaatat ggcgttgaag aatatgtcaa catacttctt
     2221 gcgattatac aggtggaatc gggcggtact gcggaagatg ttatgcagtc ctcggaatcc
     2281 ctcggtcttc cacctaattc attgagtaca gaagaatcca ttaagcaagg tgtgaagtat
     2341 ttcagtgaat tattagccag tagcgaaagg ctcagtgtag atttagaatc ggttatccag
     2401 tcctacaatt atggtggtgg tttcttaggg tatgtggcta atcgtggaaa taaatatacc
     2461 tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg gcgaaaaagt gtcttacccc
     2521 aatcccatag ccatacctat caatgggggc tggcgataca actatggcaa tatgttttat
     2581 gtgcaactgg taacgcagta tcttgtcaca acagagtttg atgatgatac ggtacaagcc
     2641 atcatggacg aagcactgaa atatgagggc tggcgatacg tttacggtgg agcttccccg
     2701 actacttctt ttgattgtag cggactgaca caatggacgt atggaaaagc tggaattaac
     2761 ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc atatcccact atcggaagca
     2821 caagctggcg atttggtttt ctttcattct acctataacg ctggctctta tattactcat
     2881 gttgggatat accttggcaa taaccgtatg tttcatgcag gcgacccaat cggttatgcc
     2941 gacttaacaa gcccctactg gcaacagcat ttagtgggag caggacgaat caaacaatga
     3001 gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa taaagaaaaa cagataccaa
     3061 aggaaaagaa acctcgtgtc tactataagg tcaatcctca taaaaaggtt gtgattgcct
     3121 tgtgggtact tttagggctt agtttcagct ttgcgatatt caagcacttt acagctatag
     3181 atactcatac tattcacgaa acaactatca tagaaaagga atacgttgat actcatcatg
     3241 tagaaaattt tgtagagaac tttgcgaaag tctactattc atgggagcaa tccgataagt
     3301 ccattgataa tcgaatggaa agtctaaaag gctatctgac agatgaactt caagctctca
     3361 atgttgatac agtacgcaaa gatattcctg tatcgtcttc tgtaagagga tttcagatat
     3421 ggacggtaga gccaactggc gacaatgagt ttaatgtaac ctacagtgta gaccagctca
     3481 ttacagaggg agaaaataca aagaccgtcc actctgctta tatagtgagt gtctatgtag
     3541 atggttctgg aaatatggta ctggttaaga atccgaccat taccaacata cctaagaaat
     3601 caagttataa accaaaagcc attgaaagtg aggggacggt tgattccatt acaaccaatg
     3661 aaatcaatga gtttttaacg acgttcttca agctctatcc tacagcgaca gccagtgaac
     3721 tttcctacta tgtgaatgac gggatattaa aaccaatcgg aaaagagtac atctttcaag
     3781 aactggtaaa tcctattcac aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg
     3841 agtatatcga ccagcagacc aaagcaacgc aggtatctca atttgatttg gtacttgaaa
     3901 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     3961 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttat
     4021 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     4081 aataaactgt caatttgata gtggaaacaa ataattggat gtcctttttt aggagggctt
     4141 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     4201 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat
     4261 cactgggatt tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt
     4321 aatattggag ttttagctca tgttgatgcg ggaaaaacta ccttaacaga aagcttatta
     4381 tataacagtg gagcgattac agaattagga agcgtggaca gaggtacaac gaaaacggat
     4441 aatacgcttt tagaacgtca gagaggaatt acaattcaga cggcgataac ctcttttcag
     4501 tggaaaaata ctaagataaa catcatagac acgccaggac atatggattt tttagcagaa
     4561 gtatatcgtt cattatcagt attagatggg gcaattctac tgatttctgc aaaagatggc
     4621 gtacaagcac aaactcgtat attgtttcat gcacttagga aaataggtat tcccacaatc
     4681 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     4741 aaagagaaac tttctgcgga aattgtaatc aaacagaagg tagaactgca tcctaatatg
     4801 cgtgtaatga actttaccga atctgaacaa tgggatatgg taatagaagg aaatgattac
     4861 cttttggaga aatatacgtc tgggaaatta ttggaagcat tagaactcga acaagaggaa
     4921 agcataagat ttcataattg ttccctgttc cctgtttatc acggaagtgc aaaaaacaat
     4981 atagggattg ataaccttat agaagtgatt acgaataaat tttattcatc aacacatcga
     5041 ggtcagtctg aactttgcgg aaaagttttc aaaattgagt attcggaaaa aagacagcgt
     5101 cttgcatata tacgtcttta tagtggcgta ctgcatttgc gagattcggt tagaatatcg
     5161 gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa taaatggtga attatgtaaa
     5221 atcgataagg cttattccgg ggaaattgtt attttgcaga atgagttttt gaagttaaat
     5281 agtgttcttg gagatacaaa gctattgcca cagagagaga gaattgaaaa tcccctccct
     5341 ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa gggaaatgtt acttgatgca
     5401 cttttagaaa tctccgacag tgacccgctt ctgcgatatt atgtggattc tgcgacacat
     5461 gaaatcatac tttctttctt agggaaagta caaatggaag tgacttgtgc tctgctgcaa
     5521 gaaaagtatc atgtggagat agaaataaaa gagcctacag tcatttatat ggaaagaccg
     5581 ttaaaaaaag cagagtatac cattcacatc gaagttccac cgaatccttt ctgggcttcc
     5641 attggtctat ctgtagcacc gcttccatta gggagcggag tacagtatga gagctcggtt
     5701 tctcttggat acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc
     5761 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     5821 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     5881 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     5941 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     6001 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     6061 tgtattcaag aatatcgtag tgatttaact tcctttacaa atggacgtag tgtttgttta
     6121 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     6181 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     6241 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     6301 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     6361 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     6421 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     6481 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     6541 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     6601 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     6661 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     6721 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     6781 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     6841 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     6901 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     6961 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     7021 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     7081 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     7141 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     7201 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     7261 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     7321 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     7381 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca
     7441 tcttcttttc agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa
     7501 gacgagcgaa agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt
     7561 tcggatgttg gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac
     7621 tttcagattt ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa
     7681 gcattacgtg agttgccaga caagaaacgt gaaattctac tgctgtttta ctttatggac
     7741 atgagcgatt cagaaattgc agacctgttg aaattgaacc gttctactgt ctatcggcat
     7801 agaaccagtg gactagcctt aattaaaaag tttatggagg aatttgaaga atgaaaacac
     7861 aatatcctat gattcccttt cctctcattg taaaggcaac agatggcgat accgaagcga
     7921 ttaaccagat tctacatcat tacagagggt acataacgaa gcgttcccta cgacttatga
     7981 aagatgaata tggcaatcaa agtatggtcg ttgatgaagt cttacgtgga agaatggaaa
     8041 ccagactgat tacaaagatt ttgtcatttg aaattaagta atatcctctc tcctttcgtg
     8101 gaagcgtgct aaaccattcc acgcttcccg aacagggagg tttgttattc caccaaagca
     8161 tattgagctt tcaatgtgtt ttgataggct aacgagccat tgttctttga aaactgaata
     8221 aaagtaatcg aat
//
